LOCUS       NZ_CP148803             7119 bp    DNA     circular CON 05-APR-2024
DEFINITION  Salmonella enterica subsp. enterica serovar Infantis strain
            Z1323HSL0002 plasmid pZ1323HSL0002-3, complete sequence.
ACCESSION   NZ_CP148803
VERSION     NZ_CP148803.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN40424068
            Assembly: GCF_037774005.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Infantis
  ORGANISM  Salmonella enterica subsp. enterica serovar Infantis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7119)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Complete genome sequence of Salmonella enterica subsp. enterica
            serovar Infantis isolated from humans, companion and industrial
            animals
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7119)
  AUTHORS   Chae,J.-C., Oh,J.Y., Jeong,J.H. and Kwak,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2024) Division of biotechnology, Jeonbuk National
            University, kobongro, Iksan 54596, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 129X
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037774005.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 20:55:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,959
            CDSs (total)                      :: 4,840
            Genes (coding)                    :: 4,658
            CDSs (with protein)               :: 4,658
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 182
            CDSs (without protein)            :: 182
            Pseudo Genes (ambiguous residues) :: 0 of 182
            Pseudo Genes (frameshifted)       :: 81 of 182
            Pseudo Genes (incomplete)         :: 134 of 182
            Pseudo Genes (internal stop)      :: 41 of 182
            Pseudo Genes (multiple problems)  :: 65 of 182
            Pseudo Genes (short protein)      :: 1 of 182
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP148803.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7119
                     /organism="Salmonella enterica subsp. enterica serovar
                     Infantis"
                     /mol_type="genomic DNA"
                     /strain="Z1323HSL0002"
                     /serovar="Infantis"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:595"
                     /plasmid="pZ1323HSL0002-3"
                     /geo_loc_name="South Korea"
                     /collection_date="2023-04-01"
     gene            510..749
                     /locus_tag="WI220_RS24645"
                     /old_locus_tag="WI220_24645"
     CDS             510..749
                     /locus_tag="WI220_RS24645"
                     /old_locus_tag="WI220_24645"
                     /inference="COORDINATES: protein motif:HMM:NF020425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA family protein"
                     /protein_id="WP_023994229.1"
                     /translation="MTPFRYNSDLTSGSLQTRKCRIITGLLLQELDEAAWDKAMYEENV
                     LQKRTQSTVRRISSALRKRLEHLSSDFWAFAFLC"
                     /name="BrxA family protein"
     gene            complement(937..1914)
                     /gene="intI2"
                     /locus_tag="WI220_RS24650"
                     /old_locus_tag="WI220_24650"
     CDS             complement(937..1914)
                     /gene="intI2"
                     /locus_tag="WI220_RS24650"
                     /old_locus_tag="WI220_24650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023994230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 2 integron integrase IntI2"
                     /protein_id="WP_023994230.1"
                     /translation="MSNSPFLNSIRTDMRQKGYALKTEKTYLHWIKRFILFHKKRHPQT
                     MGSEEVRLFLSSLANSRHVAINTQKIALNALAFLYNRFLQQPLGDIDYIPASKPRRLPS
                     VISANEVQRILQVMDTRNQVIFALLYGAGLRINECLRLRVKDFDFDNGCITVHDGKGGK
                     SRNSLLPTRLIPVIKQLIEQARLIQQDDNLQGVGPSLPFALDRKYPSAYRQAAWMFVFP
                     SSTLCNHPYNGKLCRHHLHDSVARKALKAAVQKAGIVSKRVTCHTFRHSFATHLLQAGR
                     DIRTVQELLGHTDVKTTQIYTHVLGQHFAGTTSPADGLMLLINQ"
                     /name="intI2"
     gene            2245..2718
                     /gene="dfrA14"
                     /locus_tag="WI220_RS24655"
                     /old_locus_tag="WI220_24655"
     ARG             2246..2715
                     /name="dfrA14"
                     /gene="dfrA14"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA14"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2825..3322
                     /locus_tag="WI220_RS24660"
                     /old_locus_tag="WI220_24660"
     CDS             2825..3322
                     /locus_tag="WI220_RS24660"
                     /old_locus_tag="WI220_24660"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: protein motif:HMM:NF013421.4"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]; GO:0016787 - hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="WP_058649967.1"
                     /translation="MKIKALLILFIFLPLIGCDRYTKEKAIVSLKGQEPASFFNGIFTL
                     TYHENTGGMLSLGADLPENVRHIIFTLMVGAVLLSGLAYLLIKPMNKLSFSVGLLMLSG
                     GLGNLYDRVLNEGRVVDFMLLQIGPLRTGVFNVADVAIMAGLFGFIFISSKSGKQLTNQ
                     SN"
                     /name="signal peptidase II"
     gene            <3565..3780
                     /locus_tag="WI220_RS24665"
                     /old_locus_tag="WI220_24665"
                     /pseudo=""
     CDS             <3565..3780
                     /locus_tag="WI220_RS24665"
                     /old_locus_tag="WI220_24665"
                     /inference="COORDINATES: protein motif:HMM:NF025077.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /name="DUF4156 domain-containing protein"
     gene            3854..>4203
                     /locus_tag="WI220_RS24670"
                     /old_locus_tag="WI220_24670"
                     /pseudo=""
     CDS             3854..>4203
                     /locus_tag="WI220_RS24670"
                     /old_locus_tag="WI220_24670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611486.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(4236..5102)
                     /locus_tag="WI220_RS24675"
                     /old_locus_tag="WI220_24675"
     CDS             complement(4236..5102)
                     /locus_tag="WI220_RS24675"
                     /old_locus_tag="WI220_24675"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_049885070.1"
                     /translation="MPEILATCNSPEYQSLPPSQIVPRLADKGLYLASESTFYRVLREH
                     GQANRRGRAQPPRTAPKPHAWLASAPLKTWSWDITFLPTAVRGQFYRLYMVMDVYSRMI
                     VGWEIHEDERAEHAAMLITKACLRHRVRQDALVLHADNGSPMKGATMLATLQRLGVVPS
                     FSRPAVSDDNAYSEALFRTLKYTPAYPKKPFASIEQARQWVLRFVTWYNTEHRHSGIKF
                     VTPEQRHYGQEHAILERRRTVYEAAKQAMPQRWKGRHTRDWNPIGEVWLNPPKESAADD
                     HKLSRAA"
                     /name="IS3 family transposase"
     gene            5161..>5253
                     /locus_tag="WI220_RS24680"
                     /old_locus_tag="WI220_24680"
                     /pseudo=""
     CDS             5161..>5253
                     /locus_tag="WI220_RS24680"
                     /old_locus_tag="WI220_24680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042893601.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(5259..6065)
                     /locus_tag="WI220_RS24685"
                     /old_locus_tag="WI220_24685"
     CDS             complement(5259..6065)
                     /locus_tag="WI220_RS24685"
                     /old_locus_tag="WI220_24685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_039026397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_065311492.1"
                     /translation="MAQQGDVVSVVQACRWAGLSRRSYYYQPTKAKPRVNEHLATRVKR
                     IITDLPYAGYRTVAWLLGENKNTIQRLFQIKGWQVRKRRSGARPRVQALPSVASRPNER
                     WATDTARVWCGPIHRWCALTLVIDCHTREALGWRLSPSGNAKSAEAALEEALITRYGAL
                     GRAQDPITLRSDNGLVFTSRHYTRTVYQYGLKQEFIQPHTPQQNGMVERLIRTVKEQCL
                     WLHHFKSLDEARQTLRAWFKYYNEQRPHQALGMKTPNMVYQQQLVT"
                     /name="IS3 family transposase"
     gene            complement(6086..6394)
                     /locus_tag="WI220_RS24690"
                     /old_locus_tag="WI220_24690"
     CDS             complement(6086..6394)
                     /locus_tag="WI220_RS24690"
                     /old_locus_tag="WI220_24690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011479532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1153 domain-containing protein"
                     /protein_id="WP_023994235.1"
                     /translation="MTQEPTIKRWTAKRKAELIKQIYRGQTTISEAARQYDLTQQEIET
                     WLEDAEAGMENALKANPKDIAEQYEGQLRELKEAYGEAMLELKFRKKLQRHLDSTDD"
                     /name="DUF1153 domain-containing protein"
     gene            6425..7090
                     /locus_tag="WI220_RS24695"
                     /old_locus_tag="WI220_24695"
     CDS             6425..7090
                     /locus_tag="WI220_RS24695"
                     /old_locus_tag="WI220_24695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_075322288.1"
                     /translation="MCSFSLGHYKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEM
                     EKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDFYLSSRRNSKAAYR
                     FLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHRQIKYRNNVIECDH
                     GKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPLGEMRLVSRVFEM"
                     /name="IS6 family transposase"
ORIGIN
        1 tgtgggcgga caaaatagtt gggaactggg aggggtgaaa atggggtttt taaggattat
       61 ttaggggaga gtgacaaaat agatgggaac tgggtgtagc gtcgcaagct aatgcgaaaa
      121 ttaaaaatga caaaatagtt tggaactaga tttcacttat ctggttaact aatctagcta
      181 acctgccgct cagcttagta cgatcctata tccaactgat cataatcctt tcatcagtat
      241 cccaaattaa atccccctcc tagactgcct caccaacaca ttacagtgat cccgtatttc
      301 cggacaggtg attgattttt ttcgcttgta caggtgttaa gccacagtta tcttgatgta
      361 gacattatgc attgtaatag cccattaaca tgcgctaaga gcataaatta atatacagta
      421 acaagcatta cgatgtgcta atgtttggaa agcagcctct tccaactaca ataataagtt
      481 aactatcctc cacccacaaa taattacaaa tgaccccttt ccgctataac tccgatctca
      541 ccagcggctc gctacaaacc cgaaagtgtc gcattattac tggcttgtta ctccaagagc
      601 ttgatgaagc tgcctgggat aaagccatgt atgaggaaaa tgtgcttcag aaacgcacgc
      661 aatctacggt aagacgtatt tcttcagcgc ttagaaaacg cctagaacac ctaagctctg
      721 acttttgggc ttttgcgttt ttatgttagg cattgtctgg cagctggagg aagtgtaatg
      781 accatgaatg gtcactgtga ttaacagtat cttgcttaaa cttatctgaa caatggtaga
      841 actggctcat atttatcccc tctatgattg tttatctttt tcaccataaa aagtatcagg
      901 ggctactcag ggctacataa agatatttat ctacttttac tgattgataa gtagcatcag
      961 tccatccgca ggactggtgg tgccggcaaa atgctgaccc aacacatgcg tatagatttg
     1021 cgtggtctta acatcggtat gccctaagag ttcttgcaca gtgcgaatat cacgccccgc
     1081 ttgtaataga tgcgtagcaa acgagtgacg aaatgtatga caagtgacac gcttgctaac
     1141 gatgcctgct ttttgtacgg ctgccttcaa tgcctttcgc gcaacggagt catgcagatg
     1201 atggcggcat aatttgccgt tatacgggtg gttgcagagc gtgctggagg gaaagacaaa
     1261 catccacgcc gcttgtcgat aagcagaagg gtatttgcga tctaaagcaa aaggcagcga
     1321 tggccctacg ccttgtaagt tgtcgtcttg ctgaataagc cgcgcttgct caatgagttg
     1381 ttttattact gggattaggc gcgtgggcag taggctgttt ctgcttttcc cacccttacc
     1441 gtcatgcaca gtgatgcagc cattatcaaa atcaaaatct ttaacccgca aacgcaagca
     1501 ttcattaatg cgcaaacctg caccatacag cagcgcaaaa attacttggt tgcgagtatc
     1561 cataacctgc aaaatgcgtt gcacttcatt tgcagagata acagagggta gccgtctagg
     1621 cttgcttgca gggatataat caatatcgcc caacggctgt tgtaaaaacc tgttgtacaa
     1681 aaaagctagg gcatttaaag cgattttctg cgtgtttatg gctacatgtc tgctgtttgc
     1741 taagctggat aaaaacagcc tgacctcttc actgcccatg gtctgaggat gacgtttttt
     1801 gtgaaacaga ataaaacgct taatccagtg caggtaagtt ttttcagttt tcagcgcata
     1861 acctttttgc cgcatatccg tgcgtataga atttaaaaat ggactgttag acataaaacg
     1921 ctccttgtct tgcaactgtc tgcctataca gcctattcta gctgggattt aaaaaagtgc
     1981 ctgtttttta cgcctagaga tgcttgttta ccggtagagt tttaatttaa tgctaaataa
     2041 attaaagtgt tatgagttct ttgggtgaga taatgtgcat cgtgcaagca ggatagacgg
     2101 catgcacgat ttgtaataac agagtgtctt atatttttaa agaaagtcta tttaatacaa
     2161 gtgattatat taattaacgg taagcatcag cgggtgacaa aacgagcatg cttactaata
     2221 aaatgttaac ccaggatgag aaccttgaaa gtatcattga tagctgcgaa agcgaaaaac
     2281 ggcgtgattg gttgcggtcc agacataccc tggtccgcga aaggggagca gctacttttt
     2341 aaagcattga cctacaatca gtggcttctg gtgggtcgca agacgtttga atctatgggc
     2401 gcactcccca ataggaaata cgcggtcgtt acccgctcag gttggacatc aaatgatgac
     2461 aatgtagttg tatttcagtc aatcgaagag gccatggaca ggctagctga attcaccggt
     2521 cacgttatag tgtctggtgg cggagaaatt taccgagaaa cattacccat ggcctctacg
     2581 ctccacttat cgacgatcga catcgagcca gagggggatg ttttcttccc gagtattcca
     2641 aataccttcg aagttgtttt tgagcaacac tttacttcaa acattaacta ttgctatcaa
     2701 atttggaaaa agggttaaca aagctatgca atcgacggca aaaagcttcg ttcgcttcgc
     2761 gcactacgcc tttttccgcg attgatagcg acgttagttg tacgaactga aaatcgagct
     2821 ctatatgaaa attaaagcac tacttattct ttttattttt cttcccctga ttggatgcga
     2881 tcgctacacc aaagaaaaag ctatagtttc cctcaaaggc caagagcctg cttcgttttt
     2941 caacggaatc ttcactctta cttatcacga aaataccgga ggcatgctaa gcctcggcgc
     3001 cgatctgcct gaaaacgttc ggcatattat cttcacgctc atggtaggcg ctgtcttgct
     3061 aagcgggttg gcatatctgt tgatcaagcc aatgaacaag ctaagtttta gcgttggttt
     3121 actcatgctt tctggtggcc ttgggaattt atatgatcga gttttaaatg aaggtcgagt
     3181 agttgacttt atgctgttgc agatcggccc cttaagaact ggcgtattta acgtggctga
     3241 cgttgcaatt atggctgggc tgtttggctt catttttatt tctagcaagt cgggaaagca
     3301 actaacaaat caatcaaact gatggttttt aagtcgccaa tttgcgcatg gcttcgccat
     3361 tatcacgcaa acagtcaact taaaaaccac agtttatctc agcgttatgt ttcattaggg
     3421 gaaatcatga aaaacaagat taatactttc tttatcgtag cctttgttct aaccctgtcc
     3481 gcgtgtgctg ctaaacagac aatacctggg gctgagcgag ttgagttagt aaacgatctt
     3541 cctgattgag aaaagtgcga gttcgtcggc gaggttgtgg ggtctcaggg gaattggttt
     3601 actggtgacg taacatcaaa taaaaattta gttataggcg caagaaacga attaaggaat
     3661 gaagcctata aattaggggc taatgtcgtt tatgtgcaag acttaaaaaa cacgaatgca
     3721 tatggttcta tgggcacaac aaatacaact ggtgttggta aagcatataa atgtaagtga
     3781 cctttccccc taaattagaa ccataacttc gatgagattt ccattacact gacagcagtt
     3841 ggaggtctca aaaatgaaga aacgttatac cgaagaacaa attattaagg tcattaaaga
     3901 acacgaggca ggtgccaaag taagtgatat ttgccgcagg ctaggcatct ccaatggcac
     3961 tttttataac tggcgtagta aatatgcagg actggaggta aacgaggcta aacgcctgcg
     4021 tgaacttgag tcagaaaaca acaaactcaa aaaactgttg gcagagaagc tgcttgagaa
     4081 tgaggctttg aaggatgttg tctcaaaaaa gtggtaaccc ctgccagcaa aaaattagcc
     4141 gtacgccatc tcattgatgc ttttaggcta agtgaaagat tggcttgcag gcttttgggg
     4201 ttaacggtgt ttgtcaacaa tgatgtccgt tttcttcatg cggcgcggct gagtttgtga
     4261 tcgtcggcgg cactttcttt cggcgggttt aaccacacct cgccaattgg gttccagtca
     4321 cgcgtgtggc ggcccttcca acgctgaggc atggcttgtt tcgccgcttc gtagacggtg
     4381 cggcggcgtt caagaatggc gtgctcctgc ccataatgtc gctgctcggg tgttacgaac
     4441 ttgatgccgc tgtggcggtg ctccgtgttg taccaagtca cgaagcgcag cacccattgg
     4501 cgtgcctgct cgatcgaagc aaacggcttc ttcggatagg ctggggtgta tttcagcgtt
     4561 ctgaacaggg cttcagagta ggcgttgtcg tcactcaccg ccggccgact gaacgacggc
     4621 acaacgccca gacgctgcaa ggtcgccaac atggtggcgc ctttcatggg cgagccgttg
     4681 tcggcatgta gcaccagcgc gtcttggcga actcggtgac gcaggcatgc tttggtgatg
     4741 agcatggcag catgttctgc gcgttcgtcc tcgtggattt cccagcccac aatcatgcgg
     4801 ctgtacacat ccatcaccat gtacaggcgg tagaactggc cacgaacagc ggtgggcaaa
     4861 aacgtgatgt cccagctcca ggttttcagc ggcgcacttg ccaaccatgc atgcggcttg
     4921 ggggctgttc tgggcggttg ggcacgaccg cgccgattag cttgcccatg ctcgcgcaag
     4981 acccgataaa acgtcgattc gcttgccagg taaagcccct tgtcagccaa gcggggcaca
     5041 atctgtgaag gcggcaggct ctggtattcg gggctgttgc aggtggcaag aatttctggc
     5101 actgttgcaa atagtcggtg gtgataaact tatcatcccc ttttgctgat ggagctgcac
     5161 atgaacccat tcaaaggccg gcattttcag cgtgacatca ttctgtgggc cgtacgctgg
     5221 tactgcaaat atgtaatgac ccagcgtaat ttgcacactt aagtcactaa ttgttgttga
     5281 taaaccatgt taggtgtttt cattcctaac gcttggtgag ggcgttgttc attgtaatac
     5341 ttgaaccagg cccttaacgt ttgtctggcc tcatctaagg atttgaagtg atgaagccag
     5401 agacactgct ctttaaccgt tcggattaag cgttcaacca tcccgttttg ctgtggggta
     5461 tgcggctgaa taaactcttg ctttaaaccg tattggtata ccgtacgcgt gtaatgtcga
     5521 gaggtaaaga ctagaccgtt atcactgcgt agggtgatcg gatcctgtgc tcggcctaac
     5581 gcaccatatc gagtgattaa ggcttcctct aaggcggcct cagccgactt agcattacca
     5641 ctaggactta atcgccaacc cagagcctct cgcgtatggc aatctataac aagggttaaa
     5701 gcgcaccaac gatgtatagg accacaccaa acacgtgctg tatcggttgc ccagcgttcg
     5761 ttcgggcgtg atgctaccga cggcaaggct tgaactcgtg gacgagcccc actacgacgc
     5821 ttacgcacct gccagccctt aatctggaac agacgctgaa tggtgttctt gttctcaccc
     5881 agtagccaag caacggtgcg gtagcctgca tagggtaagt cagtaataat gcgcttcaca
     5941 cgtgtggcta aatgctcatt aacacgcggt ttggccttag tgggctggta gtaataacta
     6001 cgccgtgata aacctgccca acgacaagcc tgtactacac tgaccacatc accctgctgc
     6061 gccatctcgt taataatttg ttgaattaat cgtcggtcga gtcgagatgg cgctgtagct
     6121 tttttctaaa cttcaactcc aacatcgctt ccccatacgc ttcttttaac tcacgcagct
     6181 gaccttcata ttgctcggct atatccttag gattcgcttt taaggcgttt tccataccag
     6241 cttctgcatc ctctagccac gtttcaatct cttgttgagt taaatcgtac tgacgtgccg
     6301 cctcagagat agtcgtctga ccacgataaa tctgcttaat taactccgct ttacgtttag
     6361 ccgtccagcg tttgattgtg ggttcttgcg tcatgcctta ctccaatttt agagcgacta
     6421 tagcatgtgc agcttttcac tgggtcatta caaatacggc atcagttacc gtgagctgca
     6481 ggagatgctg gctgaacgcg gagtgaatgt cgatcactcc acgatttacc gctgggttca
     6541 gcgttatgcg cctgaaatgg aaaaacggct gcgctggtac tggcgtaacc cttccgatct
     6601 ttgcccgtgg cacatggatg aaacctacgt gaaggtcaat ggccgctggg cgtatctgta
     6661 ccgggccgtc gacagccggg gccgcactgt cgatttttat ctctcctccc gtcgtaacag
     6721 caaagctgca taccggtttc tgggtaaaat cctcaacaac gtgaagaagt ggcagatccc
     6781 gcgattcatc aacacggata aagcgcccgc ctatggtcgc gcgcttgctc tgctcaaacg
     6841 cgaaggccgg tgcccgtctg acgttgaaca ccgacagatt aagtaccgga acaacgtgat
     6901 tgaatgcgat catggcaaac tgaaacggat aatcggcgcc acgctgggat ttaaatccat
     6961 gaagacggct tacgccacca tcaaaggtat tgaggtgatg cgtgcactac gcaaaggcca
     7021 ggcctcagca ttttattatg gtgatcccct gggcgaaatg cgcctggtaa gcagagtttt
     7081 tgaaatgtaa ggcctttgaa taagacaaaa ggctgcctc
//
