LOCUS       NZ_CP148080            27068 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus aureus strain BSN155-2 plasmid pSa14640, complete
            sequence.
ACCESSION   NZ_CP148080
VERSION     NZ_CP148080.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38637735
            Assembly: GCF_037482265.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Pre-publication release of Staphylococcus aureus str BSN155-2 whole
            genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Berti,A.D., Gurdziel,K. and Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2024) Pharmacy Practice, Wayne State University,
            259 Mack Ave, Detroit, MI 48201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2024
            Assembly Method                   :: SPAdes v. FEB-2024
            Assembly Name                     :: BSN155-2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: CP043386, CP053637
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037482265.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 19:23:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,959
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 44 of 83
            Pseudo Genes (incomplete)         :: 42 of 83
            Pseudo Genes (internal stop)      :: 16 of 83
            Pseudo Genes (multiple problems)  :: 18 of 83
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP148080.1.
            Bacteria and source DNA available from Andrew D. Berti, Wayne State
            University, Detroit MI  USA.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BSN155-2"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSa14640"
                     /geo_loc_name="USA: Detroit, MI"
                     /lat_lon="42.33 N 83.05 W"
                     /collection_date="2022-01-07"
                     /collected_by="Andrew D. Berti"
     gene            complement(join(26749..27068,1..19))
                     /locus_tag="UXR46_RS14635"
                     /old_locus_tag="UXR46_14635"
     CDS             complement(join(26749..27068,1..19))
                     /locus_tag="UXR46_RS14635"
                     /old_locus_tag="UXR46_14635"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="WP_078072414.1"
                     /translation="MITAGKFLNCHGDESFIKDFDSAMYKIKSILKHGEKNYAQELENS
                     INVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQEPESRMIEPISLGFYEQN
                     WYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(528..1322)
                     /gene="aph(3')-IIIa"
                     /locus_tag="UXR46_RS14640"
                     /old_locus_tag="UXR46_14640"
     ARG             complement(532..1322)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(1415..1945)
                     /gene="sat4"
                     /locus_tag="UXR46_RS14645"
                     /old_locus_tag="UXR46_14645"
     ARG             complement(1419..1945)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(1942..>2577)
                     /locus_tag="UXR46_RS14650"
                     /old_locus_tag="UXR46_14650"
                     /pseudo=""
     CDS             complement(1942..>2577)
                     /locus_tag="UXR46_RS14650"
                     /old_locus_tag="UXR46_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(2718..3392)
                     /locus_tag="UXR46_RS14655"
                     /old_locus_tag="UXR46_14655"
     CDS             complement(2718..3392)
                     /locus_tag="UXR46_RS14655"
                     /old_locus_tag="UXR46_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(<3449..3625)
                     /locus_tag="UXR46_RS14660"
                     /old_locus_tag="UXR46_14660"
                     /pseudo=""
     CDS             complement(<3449..3625)
                     /locus_tag="UXR46_RS14660"
                     /old_locus_tag="UXR46_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(3639..4376)
                     /locus_tag="UXR46_RS14665"
                     /old_locus_tag="UXR46_14665"
     CDS             complement(3639..4376)
                     /locus_tag="UXR46_RS14665"
                     /old_locus_tag="UXR46_14665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(4369..5298)
                     /locus_tag="UXR46_RS14670"
                     /old_locus_tag="UXR46_14670"
     CDS             complement(4369..5298)
                     /locus_tag="UXR46_RS14670"
                     /old_locus_tag="UXR46_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(5414..6295)
                     /locus_tag="UXR46_RS14675"
                     /old_locus_tag="UXR46_14675"
                     /pseudo=""
     CDS             complement(5414..6295)
                     /locus_tag="UXR46_RS14675"
                     /old_locus_tag="UXR46_14675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(6292..>6669)
                     /locus_tag="UXR46_RS14680"
                     /old_locus_tag="UXR46_14680"
                     /pseudo=""
     CDS             complement(6292..>6669)
                     /locus_tag="UXR46_RS14680"
                     /old_locus_tag="UXR46_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(6727..7401)
                     /locus_tag="UXR46_RS14685"
                     /old_locus_tag="UXR46_14685"
     CDS             complement(6727..7401)
                     /locus_tag="UXR46_RS14685"
                     /old_locus_tag="UXR46_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            7875..9341
                     /gene="msr(A)"
                     /locus_tag="UXR46_RS14690"
                     /old_locus_tag="UXR46_14690"
     ARG             7876..9338
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.8"
                     /coverage="100.0"
     gene            9440..10339
                     /locus_tag="UXR46_RS14695"
                     /old_locus_tag="UXR46_14695"
     CDS             9440..10339
                     /locus_tag="UXR46_RS14695"
                     /old_locus_tag="UXR46_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            10825..11433
                     /locus_tag="UXR46_RS14700"
                     /old_locus_tag="UXR46_14700"
     CDS             10825..11433
                     /locus_tag="UXR46_RS14700"
                     /old_locus_tag="UXR46_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            11679..12017
                     /locus_tag="UXR46_RS14705"
                     /old_locus_tag="UXR46_14705"
     CDS             11679..12017
                     /locus_tag="UXR46_RS14705"
                     /old_locus_tag="UXR46_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            12022..12207
                     /locus_tag="UXR46_RS14710"
                     /old_locus_tag="UXR46_14710"
     CDS             12022..12207
                     /locus_tag="UXR46_RS14710"
                     /old_locus_tag="UXR46_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(12434..13177)
                     /locus_tag="UXR46_RS14715"
                     /old_locus_tag="UXR46_14715"
     CDS             complement(12434..13177)
                     /locus_tag="UXR46_RS14715"
                     /old_locus_tag="UXR46_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            13603..14586
                     /locus_tag="UXR46_RS14720"
                     /old_locus_tag="UXR46_14720"
     CDS             13603..14586
                     /locus_tag="UXR46_RS14720"
                     /old_locus_tag="UXR46_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <14606..14895
                     /locus_tag="UXR46_RS14725"
                     /old_locus_tag="UXR46_14725"
                     /pseudo=""
     CDS             <14606..14895
                     /locus_tag="UXR46_RS14725"
                     /old_locus_tag="UXR46_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            15442..15591
                     /locus_tag="UXR46_RS14730"
                     /old_locus_tag="UXR46_14730"
     CDS             15442..15591
                     /locus_tag="UXR46_RS14730"
                     /old_locus_tag="UXR46_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15759..16451)
                     /locus_tag="UXR46_RS14735"
                     /old_locus_tag="UXR46_14735"
     CDS             complement(15759..16451)
                     /locus_tag="UXR46_RS14735"
                     /old_locus_tag="UXR46_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            16561..16755
                     /locus_tag="UXR46_RS14740"
                     /old_locus_tag="UXR46_14740"
     CDS             16561..16755
                     /locus_tag="UXR46_RS14740"
                     /old_locus_tag="UXR46_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            17871..18488
                     /gene="cadD"
                     /locus_tag="UXR46_RS14745"
                     /old_locus_tag="UXR46_14745"
     ARG             17872..18485
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            18507..18854
                     /locus_tag="UXR46_RS14750"
                     /old_locus_tag="UXR46_14750"
     CDS             18507..18854
                     /locus_tag="UXR46_RS14750"
                     /old_locus_tag="UXR46_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            19011..19103
                     /locus_tag="UXR46_RS14755"
                     /old_locus_tag="UXR46_14755"
     CDS             19011..19103
                     /locus_tag="UXR46_RS14755"
                     /old_locus_tag="UXR46_14755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(19275..20246)
                     /locus_tag="UXR46_RS14760"
                     /old_locus_tag="UXR46_14760"
     CDS             complement(19275..20246)
                     /locus_tag="UXR46_RS14760"
                     /old_locus_tag="UXR46_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            20370..20789
                     /locus_tag="UXR46_RS14765"
                     /old_locus_tag="UXR46_14765"
     CDS             20370..20789
                     /locus_tag="UXR46_RS14765"
                     /old_locus_tag="UXR46_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(21315..22160)
                     /gene="blaZ"
                     /locus_tag="UXR46_RS14770"
                     /old_locus_tag="UXR46_14770"
     ARG             complement(21319..22160)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22267..24024
                     /gene="blaR1"
                     /locus_tag="UXR46_RS14775"
                     /old_locus_tag="UXR46_14775"
     ARG             22268..24021
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            24014..24394
                     /gene="blaI"
                     /locus_tag="UXR46_RS14780"
                     /old_locus_tag="UXR46_14780"
     ARG             24015..24391
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            24658..25236
                     /locus_tag="UXR46_RS14785"
                     /old_locus_tag="UXR46_14785"
     CDS             24658..25236
                     /locus_tag="UXR46_RS14785"
                     /old_locus_tag="UXR46_14785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(25459..25644)
                     /locus_tag="UXR46_RS14790"
                     /old_locus_tag="UXR46_14790"
     CDS             complement(25459..25644)
                     /locus_tag="UXR46_RS14790"
                     /old_locus_tag="UXR46_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            25906..26580
                     /locus_tag="UXR46_RS14795"
                     /old_locus_tag="UXR46_14795"
     CDS             25906..26580
                     /locus_tag="UXR46_RS14795"
                     /old_locus_tag="UXR46_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     ARG             9441..10336
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7876..9341
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.16"
                     /coverage="100.0"
     ARG             9441..10339
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(1416..1933)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(2240..2541)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(21316..22160)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          14952..15099
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(12435..13177)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13604..14586
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          14718..14887
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 atttccctgc tgtaatcaat gcacccactt ccgccgctgt aaacattacc ggcagaagta
       61 ggaagccctc tacaagaaaa tatccttttc cggcctcaga tccaattggt attccggctt
      121 cttcaagtgt ccggatatct ctgtaaactg tccttaagct tatattaaat cgctgtgcaa
      181 tttctttggc aggaattatt tttttgattg cagctgaata agaatagagg ttactctgtt
      241 aatcctgttc aaattttatt cctcctctgt gacttccata aaaagtatat cctatgcgtt
      301 cttaagctag ctgctgttag tgcttctcat tgcaccctgg ttataaaagc catactcaca
      361 aacctcttca ccaaaactct ttacatctct aatatagaac tctatctagc gaacttttag
      421 aaaagatata aaacatcaga gtatggacag ttgcggatgt acttcagaaa agattagatg
      481 tctaaaaagc ttgtagttaa agctttttag acatctaaat ctaggtacta aaacaattca
      541 tccagtaaaa tataatattt tattttctcc caatcaggct tgatccccag taagtcaaaa
      601 aatagctcga catactgttc ttccccgata tcctccctga tcgaccggac gcagaaggca
      661 atgtcatacc acttgtccgc cctgccgctt ctcccaagat caataaagcc acttactttg
      721 ccatctttca caaagatgtt gctgtctccc aggtcgccgt gggaaaagac aagttcctct
      781 tcgggctttt ccgtctttaa aaaatcatac agctcgcgcg gatctttaaa tggagtgtct
      841 tcttcccagt tttcgcaatc cacatcggcc agatcgttat tcagtaagta atccaattcg
      901 gctaagcggc tgtctaagct attcgtatag ggacaatccg atatgtcgat ggagtgaaag
      961 agcctgatgc actccgcata cagctcgata atcttttcag ggctttgttc atcttcatac
     1021 tcttccgagc aaaggacgcc atcggcctca ctcatgagca gattgctcca gccatcatgc
     1081 cgttcaaagt gcaggacctt tggaacaggc agctttcctt ccagccatag catcatgtcc
     1141 ttttcccgtt ccacatcata ggtggtccct ttataccggc tgtccgtcat ttttaaatat
     1201 aggttttcat tttctcccac cagcttatat accttagcag gagacattcc ttccgtatct
     1261 tttacgcagc ggtatttttc gatcagtttt ttcaattccg gtgatattct cattttagcc
     1321 atttattatt tccttcctct tttctacagt atttaaagat accccaagaa gctaattata
     1381 acaagacgaa ctccaattca ctgttccttg cattctaaaa ccttaaatac cagaaaacag
     1441 ctttttcaaa gttggcgtat aacatagtat cgacggagcc gattttgaaa ccacaattat
     1501 gatagaattt acaagctata aggttattgt cctgggtttc aagcattagt ccatgcaagt
     1561 ttttatgctt tgcccattct atagatatat tgataagcgc gctgcctatg ccttgccccc
     1621 tgaaatcctt acatacggcg atatcttcta tataagcgta ccggttccaa ttttttcgca
     1681 gtttaacttt tccgacgcat ttatcgtctt ggtagtaaag atatattatc ttatcagtat
     1741 tgtcaatata ttcaaggcaa tctgcctcct catcctcttc atcctcttcg tcttggtagc
     1801 tttttaaata tggcgcttca tagagtaatt ctgtaaaggt ccaattctcg ttttcatacc
     1861 tcggtataat cttacctatc acctcaaatg gttcgctggg tttatcgata tctttcaggt
     1921 gccctgcttt catttctgta atcactgttc ccgcctctct tctatatcag cggcatatgt
     1981 gctatccagg cagccggttt taccagtgta ttttttatac atgtccctgg tatattttgt
     2041 tatattccta tcatactccg gataggcata atgaagcctt tccgccacct caccggatac
     2101 cgccctgaac aattgatggc atagaaataa tgcttcccat atgttttcat aggaatccat
     2161 ccggtaggtg gacaaaagtt tctcccacaa atcctcggat atataccttt caataaactt
     2221 atagttcttg cctacacttc atttaaagcc tgtttcgatg ccgaccttcc atgatatcat
     2281 tctcagcagc tcatggcgaa caatctgatt aaaatgatca atagcaaata aaatttcctt
     2341 acggcacaat cctttaataa cataaggtgt tacattccaa aattcattgc agcaatcatc
     2401 atactccctt gcgcttggct ttcttacatg ataatctata tcagtcggaa ctatgtccct
     2461 tttaattcta caatctttat caattagaac ctttattaat ttatcgccct ttaggtaatt
     2521 atctaactct tccaagggca ataaggtaag atcaatttta ttgtaatcat caaatagcta
     2581 taatagattt agaggtaaag aaattaaata cattgaagag cagaaagatt ttacaaaaga
     2641 gtattttaat aaaaatgatg gttctgttgc aaagtaaaaa atatagctaa tcactaatat
     2701 atcatgtcag tgttcgttta acttgctagc atgatgctaa tttcgtggca tggcgaaaat
     2761 ccgtagatct gaagagacct gcggttcttt ttatatagag cgtaaataca ctcaatacct
     2821 tttaaagtat tctttgctgt attgatactt tgataccttg tctttcttac tttaatatga
     2881 cggtgatctt gctcaatgag gttattcaga tatttcgatg tacaatgaca gtcaggttta
     2941 agtttaaaag ctttaattat tttagccatt gctgccttcg ttgaaggtgc ctgatctgta
     3001 actacctttt gaggcttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa
     3061 tgattatctc gttgcttacg caaccaaata tctaatgtat gtccctctgt atcaatggca
     3121 cgatataaat agctccattt tccttttatt ttgatatacg tctcatcaat acgccatttg
     3181 taataagctt ttttatgctt tttcttccaa atttgatata aaattggggc atattcttga
     3241 acccaacggt agatcgttga atgatgaacg tttacaccac gttctcttaa tatttcagat
     3301 atatcacgat agctcaatgc atatcttaga tagtagccaa cggctacagt gataacatcc
     3361 ttgttaaatt gtttatatct gaaatagttc atacagaaga ctcctttttg ttaaaattat
     3421 attataaatt caactttgca acagaacctc ctaactgtat taccacctta aaagtagttg
     3481 cagacgcact tcctaaatcg tcagcagtgt ttaaccacat atcatcaaca ataatcatat
     3541 gacctgttga tgatactgga gcaaattctg tcaacccttc aactacacct aaaataaatg
     3601 ctttaatctg ctctataaaa cccatttttc tcctcctttt aacttatatc agttttttta
     3661 aagtatgaga ataatataat tacactgaat atagatgtaa caattatgat aattaaagat
     3721 aatagaaatg gataagtatt aggtaatgtt cctctagata tgtctccaac tgcagcccaa
     3781 ggaaataatc ctctatgttc agaattagca gtcattaaat ttatcaaagt aattattatg
     3841 gttaaaacaa ttgtgggaac ataattttta aaatatatcg acaaaataat tattggtgga
     3901 gataatatcc ataataacac tccgccaata acaaatgtaa agaatgaatc aattattaaa
     3961 ctctggctta acccttgaaa atgcaatagc atacctagca ttaaagttag caaccatgca
     4021 ataacagata gtgtttgaat ccacaagaat aataatatta ttttacttac taaaaaactt
     4081 tctctagata taggtataat taataagttt tttaaagtat cttctatata ttctcttcca
     4141 aacaaatagg ctattataac cccatataga ggaggtccaa taattagcat atgatataaa
     4201 ctgacttctt caaataactg tttaaataca atattaggag tcggtacttt cgtccgcata
     4261 ctaataaaag aagctacaac caccataaaa ggtgctacgc atgtacctaa aatacttatt
     4321 agaaacatat atgatctttt taacttaata aattctgtac ggagtagatt atccaattgt
     4381 gccacctcct actaagtctt cgaaataagt ttctagatta tcttctatca ctctcatctg
     4441 gaaaacatca atattgttta atactaataa tctattaatt tcttgttgtc tatcaatatg
     4501 tgaataaatt ttaaattcgc cattttcttt aattttatag tcataaattc cgaagttagt
     4561 ttccaacaaa catgcaactt tttcttcatc tgatactgat atacttataa attgtctgtt
     4621 cttttttttt aaatcttcat acataatttc ttctaacaaa actccgttat gaataatacc
     4681 caccttgtct actaactgct ctatttctga caatatatga cttgaaatta aaatggttat
     4741 atttctagat tgagccagat ccttaatcaa ctttctaatt tcttttatgc caataggatc
     4801 taatccattc gtcggctcat caagtatcaa taattcggga ttgtgcaata aagctctcgc
     4861 aatccctaaa cgttgcttca tacctaaaga ataattttta aacaatttta ctttttcaga
     4921 agctagtcct actatttcta acacttcttc aattgcattt tctttttgta tacctaatat
     4981 tttagcattt atagttaagt tctctttagc tgtcaaatta ctataaaaac ctggcgtttc
     5041 aaccatagca ccaatatttt ttaaaatttc agttttatta ctttcgaact ctttttcaaa
     5101 tattttaata ttacctttcg taggtttaat taagcctaaa agcattctta tagtagttgt
     5161 tttgcctgca ccatttcttc ctaaaaaacc ataaatttgt ccactttcaa cagttatact
     5221 caaattatta actgctatct gacttccata ttgctttgtt aagttattta tttcaattat
     5281 attattcaaa tttttcacct ctggcacctt tcttagtttg ttgttacctt tatcttacgc
     5341 gcgattagaa aaggctgcct ttatctattc ttacaaaaac agccgctaat cttacaaaaa
     5401 tgaaagattg gagttattta aattgaatgg tgaatattga accatcgttt aatgtagatg
     5461 tagcacttac tttatggcct aagcgctttg agattgtgct gacaatatat aaaccaatac
     5521 cgcttgattt ctcacttatt ctaccgttat agcccgagaa acctttatca aagattttcg
     5581 gtaaatcact cgcattaatg ccgataccgt tatctcggat tgataatttc tttgtatttt
     5641 cgtcaaacgt aatccacaca tctttgccac gtgcatattt taatgcattg tttaatattt
     5701 gctcaatcat aattgatgcc catttggcat ctgttaatat aaccgcttca cttttctcat
     5761 aatgcaactt tgtttgatga tgaataaact gtatcgcata acgtttaatc agtggtcgaa
     5821 ttaattcatc tacactcact tccataaaga ccatgtatgt cttttggttc atgagtttca
     5881 aatagttcag tgcaagattc gtgtaattat caatttgtaa gacttcatta cgcacgttag
     5941 aaatcacgtg ttcatcagga tcttcaagca gtaactttga tgctgtaatc ggtgtcttga
     6001 tttgatgcac ccacattaaa aaatatgact ctaactcact ttggtagtta ataaagtcat
     6061 tacgaagttt atggttttcg attcttaaat cttcgttctg ttcctgtagt gtttattctt
     6121 ttttaaagtt catgtaatgg ataccccagt aaatcattga aacaaacaat acaataccta
     6181 gaccaatcat atatgcttgc atcggcacat tatacatgaa taatataaag tagaataaag
     6241 cacaagtaag gatgacaata taaatttcac gttggattga tttcaagaaa ttcatacgtc
     6301 acctacacga tatccgacat ttttcttcgt ttcgataaaa tctgtaagtc ctagtttttg
     6361 tagctttttg cgtaaacgtg taatgttgac agcaagcgta ttgtcatcaa tgaagtgttc
     6421 tgattcccag catttttcga ttaacgcatt acgactgacg aatttgccct tgttctggaa
     6481 taagctatgc atgatttgca attcagtgtg tgtcaggtct atggtttctt cattaaattt
     6541 aagctttgct gcatcaagta gtaactcgca atcatctact gttaaattat taacttgagt
     6601 ggtgaaatca tacgtgcggc gtaatagtgc ttgaatctta gtaattgtaa cagtcatatt
     6661 aaatggctgg ttctgttgca aagtaaaaaa tatagctaat cactaatata tcatgtcagt
     6721 gttcgtttaa cttgctagca tgatgctaat ttcgtggcat ggggaaaatc cgtagatctg
     6781 aagagaccta cggttctttt tatatagagc gtaaatacat tcaatacctt ttaaagtatt
     6841 ctttgccgta ttgatacttt gatatcttgt ctttcttact ttaatatgac ggtgatcttg
     6901 ctcaatgagg ttattcagat atttcgatgt acaatgacag tcaggtttaa gtttaaaagc
     6961 tttaattatt ttagccattg ctgccttcgt tgaaggtgcc tgatctgtaa ctaccttttg
     7021 aggcttacca aattgtttaa tgagacgttt gataaacgca tatgctgaat gattatctcg
     7081 ttgcttacgc aaccaaatat ctaatgtatg tccctctgta tcaatggcac gatataaata
     7141 gctccatttt ccttttattt tgatatacgt ctcatcaata cgccatttgt aataagcttt
     7201 tttatgcttt ttcttccaaa tttgatataa aattggggca tattcttgaa cccaacggta
     7261 gatcgttgaa tgatgaacgt ttacaccacg ttctcttaat atttcagata tatcacgata
     7321 gctcaatgca tatcttagat agtagccaac ggctacagtg ataacatcct tgttaaattg
     7381 tttatatctg aaatagttca tacagaagac tcctttttgt taaaattata ttataaattc
     7441 aactttgcaa cagaaccgta ttttatgagt acactctaaa ttaaggagat gtataatcaa
     7501 tctaaaattg tatttttata cttttgttat ataatctttc tacttagaga tatattgtaa
     7561 aaaaaccaac aaaatgttat attaacatta ctattttatc gatgaaggag gattaaaatg
     7621 acagcttcta tgagactcaa ataaaccttt ttgaatacaa aactaaatta attcaaaaag
     7681 gcttgtccgc aatacacact cataggatga cttatgtcat tttttatcct tcgataggaa
     7741 taataaacgc tttcaaatac taaaacatca taataaattt ttaagtgttt gaaagtgtaa
     7801 tgtgaatgag acgggagtag cctgtctcat ttttttgcgt acacgtcctt taaatataca
     7861 aggagtgtat aaatatggaa caatatacaa ttaaatttaa ccaaatcaat cataaattga
     7921 cagatttacg atcacttaac atcggtcatc tttacgctta ccaatttgaa aaaatagcac
     7981 ttattggggg taatggtact ggcaaaacca cattactaaa tatgattgct caaaaaacaa
     8041 aaccagaatc tggaacagtt gaaacggttg gcgaaattca atattttgaa cagcttaaca
     8101 tggatgtgga aaatgatttt aacacgttag acggtagttt aatgagtgaa ctccatatac
     8161 ctatgcatac aaccgacagt atgagtggtg gtgaaaaagc aaaatataaa ttagctaatg
     8221 tcatatcaaa ttatagtccg atattacttt tagatgaacc tacaaatcac ttggataaaa
     8281 ttggtaaaga ttatctgaaa aatattttaa aatattacta tggtacttta attatagtaa
     8341 gtcatgatag agcacttata tcccaaattg ctgacacaat ttgggatata caagaagatg
     8401 gcacaataag agtgtttaaa ggtaattaca cacagtatca aaatcaatat gaacaagaac
     8461 agttagaaca acaacgtcaa tatgaacagt atataagtga aaaacaaaga ttgtcccaag
     8521 ccagtaaagc taaacgaaat caagcgcaac aaatggcaca agcatcatca aaacaaaaaa
     8581 acaaaagtat agcaccagat cgtttaagtg catcaaaaca aaaaggcacg gttgagaagg
     8641 ctgctcaaaa acaagctaag catattgaaa aaagaatgga acatttggaa gaagttgaaa
     8701 aaccacaaag ttatcatgaa ttcaatttcc cacaaaataa aatttatgat atccataata
     8761 attatccaat cattgcacaa aatctaacat tggttaaagg aagtcaaaaa ctgctaacac
     8821 aagtacgatt ccaaatacca tatggcaaaa atatagcgct cgtaggtgca aatggtgtag
     8881 gtaagacaac tttacttgaa gctatttacc accaaataga gggaattgat tgttctccta
     8941 aagtgcaaat ggcatactat cgtcaacttg cttatgaaga catgcgtgac gtttcattat
     9001 tgcaatattt aatggatgaa acggattcat cagaatcatt cagtagagct attttaaata
     9061 acttgggttt aaatgaagca cttgatcgtt cttgtaatgt tttgagtggt ggggaaagaa
     9121 cgaaattatc gttagcagta ttattttcaa cgaaagcgaa tatgttaatt ttggatgaac
     9181 caactaattt tttagatatt aaaacattag aagcattaga aatgtttatg aataaatatc
     9241 ctggaatcat tttgtttaca tcacatgata caaggtttgt taaacatgta tcagataaaa
     9301 aatgggaatt aacaggacaa tctcttcatg atataactta aaaactatac actaatttat
     9361 attgaatatt aggttcattt atatcaatat aaaaaatacg ttcacaagaa aaatataata
     9421 gaaataagga tccaataaaa tgactcgaca taatgaaatt attaaatgtg cagaaaaata
     9481 tcaattacac atccaacctc aaacaatctc attgaatgaa tcgggacttg attttcaagt
     9541 tgcatttgga aaagataaac atggagtaga atgggttttg agactaccaa gaagacctga
     9601 cgtttataaa cgaacaaaac ccgaaaaaca aacggtagac ttcttacaga agaatgtttc
     9661 atttgaaata ccgaagtgga aagtacatgc aaaagacctt attgcttacc caaaacttac
     9721 aggtaaaccc gcagccacaa tagatccaga aatacaaaat tatgtatggg aaattgaaca
     9781 caaaccatta ccagaaaact ttattaacac attagctgaa acactcgtag atttacacaa
     9841 cataccagaa gaaaacatta acgttcagca tataaatatc aaaaccatac aagaaataaa
     9901 aaatgacttt caaagaagaa tgaataaagt taaagaaact tatggcgtat cagatgaatt
     9961 atggaacaga tggaaacaat ggttagaaaa cgacgaacta tggcctcgac atgcgaccat
    10021 gatacatggg gacttacatc caggacatat aatggtagat aaccaagcaa acgtcacagg
    10081 tctcatagac tggactgaag caacccactc cgacccatca atggacttta taggacacca
    10141 tcgtgtattc gacgacgaag gattagagca acttataaca gcatacggta aagctggagg
    10201 tgaaatatgg ccacgaatga aagagcatat aatagaactc aatgcagtat tcccaatgtt
    10261 tatcgctgag tttgctatgg aatcaggaga atcggcgtat gaaacgatgg cattgaaaga
    10321 gttaggtatg aaagagtaga acttatatta aaagaggccc attttaaaga cgaaggcaat
    10381 cctgatgaaa ttttaaaact gcgtttaatt agtgatggtc tttggttttc tataatgtat
    10441 taaatatctg gacatggaac aaatgcaaca aatggaaaga atcgttttcg aaatttctaa
    10501 ctccttaaat caggaggata aataaacggt cattttcatt gaaagcactt atataaattt
    10561 catcaatttt aatacctacc gtaaatacat ttcataagta ttaaacagat gattaaaatt
    10621 tttagttaat ttaaatattt atgatagaga tgaccttcaa atgaacggtt ctgttacaaa
    10681 gaaaaaatct atatttattt ttagtaagtt ttaattatag atatgtacac tttgagtaca
    10741 ccctaaccat acaaaaagaa ttgttgaaat tataacaatt aaaacgtatg attagggtgt
    10801 atatttatta tggagtgaag atgaatgatt ataggttatg cgagagtatc atcgatagat
    10861 caaaatttag aaagacaatt ggataattta aagacgtttg gtgtggagaa aatctttaca
    10921 gagaaacagt cgggaaagtc agtggaaaat agacctgtat ttcaagaagc actcaatttt
    10981 gtcagaatgg gagatcgatt cgttgtggaa tctattgatc gtttaggacg taactatgat
    11041 gaaattattg aaactgtgaa ttatttaaaa gaaaaagacg ttcagttaat gattaccagc
    11101 ttacctatga tgaatgaagt aattggcaat ccattactgg ataagtttat gaaagattta
    11161 atcattcaaa tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa
    11221 gcgcaaggga ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc tttactttat
    11281 tcaccaaatg ctaaagaccc acagaaacgt gttatttatc atcgcgtggt ggaaatgtta
    11341 gaagaaggca aagcgattag taagattgcg aaagaagtta atatcacaag acaaacagtt
    11401 tatagaatta aacatgataa gggattatct tgataaattg attgtcaatg caaatgagcg
    11461 tctctcacag tgtctcaaat tccataacat attattgaat tgagatttta ataattatac
    11521 aagaaaaaag agtacgagtt cgcagctttc tatatagtaa ttgttttact aataaggtgt
    11581 tttaaaatat attataatgt aaaaagtatt tgacatttgt atcaaaaata tttacactca
    11641 taaatgtcaa atacttttta catttatgag gtgttataat gaatttaatt ccttttatta
    11701 ttattttaat tttttcttgt ttatggacgg ctataactaa caaatattta ccttcagaaa
    11761 cattagataa aaaaggacaa caagatcgat acgatgaaag acaacgtaaa atgtttattg
    11821 aaatactggc taaaagtttt atttggattg tatattgtat gttatttaca ctagtgctta
    11881 aatttacagg tttgtcacca agtattgaag gatcttggtt ttctcaatat ccagaaattt
    11941 tctttataat tgtagcacta tttcttatgc tgtttaatta ctatactaca aataaaaaat
    12001 atacatctaa aggttaaatt aatgaaaaat agaattagag aatatagaaa acaaaaagga
    12061 atttctcaag aaactttaag taaagaatta aaagtgtcta ggcaaactat taatgcaata
    12121 gaaaacaata aatatgatcc tacattgaca ttagcattta agttggcaag attgtttgat
    12181 acaactgtgg atgaattatt ttcttaacca ttcatttatc acaaaaagag agtgcgaatt
    12241 cgcactctct ttttgtgtag tagtactatt aaattttgtc tcaataacga acgtttataa
    12301 cgcaatcatg atgagagtat taatacagtt aattatttga aatactttag tttacataat
    12361 cgatgattac cagaagttct cactatataa aagacactaa aattttataa cttttagtgc
    12421 ctaatcaatt attttagcta ccaaacaaac gactccaaaa ccccttttta ggttccgttt
    12481 cttcactctt ttcttctata tcactatcat tgtcatttag attagctgga acgtcttctt
    12541 tttttgcttc ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt
    12601 gaatctctgt ttctttagtt tcttcctgat ctctgttaat atttacagga ttagtagtat
    12661 atgttttttc ttgtgcatca acgttttgtc tagtgttagt agatgtatca aagggataat
    12721 taaggtgttt ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta
    12781 atgccagaac ttgctgattt tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa
    12841 attcaattgt tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtatcaa
    12901 tctgattttt aaggatttct actatttgag catcgctttt cgattcaaaa ttaatattat
    12961 ccgacccttt tttttgtttg tcttcagtag tactttcaaa accatatttc tttttatttt
    13021 catttactct ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt
    13081 cctgttttat tgtctctata ttcaatcgct taatattatt aaaaatcgtt tgcttactaa
    13141 cccctaattc ttcactcaac tttttcacac ttttcatatc atcaaccctt tataaaatgt
    13201 ttataaaccc ttgataaaat attataagct tataatgctt aataataaag tgattaataa
    13261 ataaaaataa acatccatca acctttttac caagggttta tgaaaggttt atgatattta
    13321 tcaagggttt ataaaccctt gataaagcta tattttccct tttataagtt tatttaaagt
    13381 gctataataa acttaatata acaaaaaccc caactactgg taatagtcgg ggtttggtaa
    13441 taaaacgttt agaaactgtt tatttatata attttcgata cttgtattat ataatgaata
    13501 atatcttagt gcaagcacct aaatcattaa ataaatgtaa agctaaataa aaacgtttta
    13561 ttacctctta ccaaactaaa atatggaaag aggttttttg tcatgcaaaa tcaatatttt
    13621 acagtgcaag aaaattacaa agaaagattt tatcaaatcc ctaaagtatt ctttaccagt
    13681 gaaaattata aaaatctaac taatgatatg aaaatagcct atgctatctt acgtgatcgc
    13741 ttaaatttat ctattaaaaa tagctgggtt gatgaagatg gtaacattta ctttgtttat
    13801 tcaaatgaaa agctaatgga aatcttaaat tgtaaaaaag aaaagttaac aaaaataaaa
    13861 aaagggttag aaaacgatgg tctactcatt caaaaacgac gtggtttaaa taaaccaaat
    13921 attctatatt taatgaaacc tattgtcaca gaacgtgata tttacaaaat agaaaaagaa
    13981 gaaaacgatg ttgaacctta cggcgagaag gaagttcgaa aatcgaacgt ccagaagttc
    14041 gaaaatcgaa cgtccagaag ttcgaaaatc gaacgtccag aagttcgaaa atcgaacact
    14101 aatgatactg actttaatga cattgacttt aatgatactg agaataatga tatgaatgac
    14161 ttgaatgata taaagtacaa aaatgaaatt agtaatcatt caaatcattc aaatcaattt
    14221 acacataatt ttgatgataa agaaatgcta ttgcaagaat tcccagaaca actaactaat
    14281 tatttattaa aatatgatta tagagattta gaaatcataa aggctgttat tcttaaagca
    14341 aaaaaatcat ttaattcaag gcatgaagat atgcattaca tgttagagga cattgaggat
    14401 gaaatattaa cttctttaaa aagacttaaa aaagctatac atgatagggg agttaaaggc
    14461 caaaaggaaa caatcaagtc aatgcaagct tatttaatgc aaacaattct aactgaactt
    14521 gaagaaacac atgcccttta tatgcgccgt aaaaacatga aacaatataa tatctttaat
    14581 caataattca aatgatttta taacactcga agagacatca aaatattccg ttaaatcatc
    14641 tgacttttta actgatgacg acgaaaaaaa tcaagaaatt gtaagtgatt tagaaaaagg
    14701 tttgtatcga aaacgtatgt taagttatgg tggattgctt aaacaaaagc ataaaatttt
    14761 aaacttagac gatgccgaag atggtaattt gattaataca agtgatgaag ataaaacgac
    14821 agacgaagaa aaaaagcaca ttcaattacc gcaatttgga atttcgaaaa gcaaaattat
    14881 tatttaagac attagtgata actgatgtct ttttttattg tttttctgta aaaaagtgct
    14941 gtcttatttt tgtgacaaat gctgtatgta gtgtcacaaa agtgtgacac tacagctttg
    15001 tatgatatca ctttaaaata acttaaaacc cttggaatgt ctggccttgc cagatctatc
    15061 atttttgaat gatagcaaat ttcccttatg ctcttacgga gattttagag ttaaattaaa
    15121 atttctaagt ttttgataag aaaagccctg caggaattta gaaaaacatg gggaagtttt
    15181 aaagtatttt atgctaattt ttaaatttgc atgtaaatgg gcagtatcta aaaaattagt
    15241 cactgatttt gctgaaattt ttgtttgtga aattagcata tatttatttg gctcatattt
    15301 gcgttttaag agactgtata gatttttaag tacaaaacct atatgatttg cctctaagtc
    15361 ttcaaaatgc ctcttaaaat ccaaaataaa agtgtttaat attgtaataa ggattgctat
    15421 ttttataaaa ggagagatat catgaagatt aaaactttcg ctacttttac tcatcgtcaa
    15481 ttagataaac aagttaatag gtttttaaag aatgatattc atgtattaga aattcaaaca
    15541 cacagtaatt ggttatatat ttcagctatt gttttttatg aggataaata aggaacatcg
    15601 tatttatgcc gaaaaaattt attgatgttg agaagaaccc ttaactaaac ttgcagacga
    15661 atgtcggcat agcgtgagct attaagccga ccattcgaca agttttggga ttgttaaggg
    15721 ttccgaggct caacgtcaat aaaacaattg gaataaaatc aacctacaga gcatccagct
    15781 gcaaatgcag ttccgcaaac tgcttcacat acaccgccgg ctattggatt tacgattgcc
    15841 catactccac agtagtgagc acatgcataa agtccagcca tactacaagc gaatgctttg
    15901 ccgttccatt tgaatcctgc atatgttacc ggtctgtttt tatcaacttt ttcagcctta
    15961 tattcaacgt aatttttgtt aataagtatt tttccctctt tgttttcagt catacttctt
    16021 ttttcggcaa tgaattttgt gatttttttg ttgtagttat catatattgt ttcagaaact
    16081 acaatttctt ttgttttttc atttttataa gcgttattag ctatgtagcc atatgcattt
    16141 ttatcatttg cttctgtagc tagatatttt aatttagaat ttttgtcttc tagctttatt
    16201 tttttaaatc cttctttttt catttgcttt tcgaattttt gcatatcttc atttttattt
    16261 tgcaattgtt ctagaaaact tatttctttc ttggtcattt gtgatacttc gatgtttttg
    16321 cttttcaatt tttctttttg attttctagt aaagaacttt tttgttcttc atttgcgtaa
    16381 gcattagaaa aattcgcgct aaataccagt aggaacaagg aaattattga aaataatttt
    16441 ataattttca tttgatacct ccaagataat aagatatttt aattgtataa gtaagcgctt
    16501 tataaaatca atatttattt taatatattt ataaacatat ttttgaaagg agtctatttt
    16561 atgaatgaaa atttagaaaa atatataaaa agtttgccac ttttaggttt gttaattagt
    16621 attttgttaa ttgttttatt cttttttatt ttagatgttg atgaagattt attcgtggtt
    16681 tttttatact gtttattgcc tttgatagtt aatttgtcta tttatggttt ttatgttttt
    16741 gttaaaagaa agtaagatta tgaataattt tgtttttaat ttgtatgctt tgagggggtt
    16801 ggaaaacggt aggtgtatag attagatttc ttgttttttt gaaacgagtg tgaacgagtt
    16861 tcttcttgtc ttgatttttg ataaaaacgc cctacaggaa tttagaaaaa cgtggggaag
    16921 ttttaaagaa ttttatgcta atttttaatt tgcatgtaaa tgggcagtgt ctaaaaatag
    16981 ttattgtttt tgctcaaatt tttgtttttg aaaatagcat atatttattt ggctcatatt
    17041 tgcgttttaa aagcatatat aagttttaga tataaaacta tatgaatcac ccctaaatct
    17101 ttaaaatgcc ctcttaaaat tcaaaataag ggcataaaaa ataaaagcta ccccagataa
    17161 agtgaggtag ctttttcttt catacggtct atttattttt ctttcgacgc cgtatcgtcg
    17221 atgtaattca aaaaagttat gggctataaa tctacatcac tttttcaaga atgtagtagc
    17281 aatattcaac gcaaattaat ttttataact gctcggaata tctcaagccg tttctttaat
    17341 tttgaaataa aaaaatcgac gaaggtcgat tacgtttttg cacatgtcga tttatccgac
    17401 gtataagtgc gcccttacgg gatttaacta gattataacg acgaatttta gacctgtaaa
    17461 gcaataacaa ttaggtctac caggtagata aagtgtacaa agtagaaccg aaaaagttat
    17521 ttattttgaa gatttttcgt agatataatt tgctaataaa cttcctaaaa ctgaataaag
    17581 aaaaatagtt aaactcatgt aatcactcca taattctgaa gtgtctccat gtctacgcat
    17641 agacacgcat ttatgccgaa aaaatttatt gatgttgaga agaaccctta actaaacttg
    17701 cagacgaatg tcggcatagc gtgagctatt aagccgacca ttcgacaagt tttgggattg
    17761 ttaagggttc cgaggctcaa cgtcaataaa gcaattggaa taaagcacct atgattattt
    17821 aaaaatataa gttataatac attcaaaaat atttttgaat gaggtgtatt atgattcaaa
    17881 cggttgttgc tgctgctgtt ctttatattg ctacagcagt tgatttatta gtaattttat
    17941 taatattttt tgctagagca aagactagaa aagaatatag agatatttat gttggtcaat
    18001 atttagggtc tattatttta atattagtta gtttgttttt agcttttgta ttaaattatg
    18061 ttccagaaaa gtggatatta ggtttattgg gtttaatacc aatttatctt ggaattaaag
    18121 tggctattta tgatgattgt gaaggagaaa agagagctaa aaaagaattg aatgaaaaag
    18181 gattgtctaa attagttggt acggttgcaa ttgttacgat agcaagttgt ggcgccgata
    18241 atattggttt atttgttccg tattttgtga cattaagtgt tactaattta ttacttactc
    18301 tgtttgtctt tttaatttta attttcttct tggtgtttac tgcacaaaaa ttagctaata
    18361 ttccaggaat tggagaaatt gttgagaaat ttagtcgttg gattatggct attatttata
    18421 tagctttagg tttatttatt attattgaaa atgacactat tcaaacaatt ttaggattta
    18481 tattttaatt tagggtgtga ttttatatga gttatgaaaa tacttgtgat gtgatctgtg
    18541 tacatgagga taaagttaac aatgctttaa gttttttaga agatgataaa tctaagaaat
    18601 tacttaacat tttagaaaaa atttgtgatg agaagaaatt gaaaatcata ttatctttga
    18661 ttaaagaaga tgagttgtgt gtttgtgata tttctttgat attgaaaatg agtgttgctt
    18721 caacttcaca tcatttaagg cttttatata aaaatgaggt acttgatttt tataaagatg
    18781 gaaagatggc atattatttt attaaagacg atgaaataag agagtttttc tctaaaaatc
    18841 atgagggttt ttgaaacgag tttcttcttg tcttgatact ataaaaaaca aagttatata
    18901 acataagacg acttatcgga agtagatatg cttgtatatt cacagatggt ataataatag
    18961 agtcgcctat ctctcaggcg tcaattgacg aagagaggag gtgcattact ttgctaatca
    19021 ttttcgttca catcatagca ccagtcatca gtggctgtgc tgttgcgtat tatacttatt
    19081 ggcttagtaa acgcaacaaa taattaatag gcgactttat aagccagcat cgaaaaaatc
    19141 cccacactac tgcaatagtg tggggattgg tgcattaatt gttaatcatt ttcgttatat
    19201 aaattataac actggttagt agagaaatgc aaaatgattg aattaatagt aaatgtatta
    19261 atgaatactc acacttatac ttttaaaata gttcttccta aatgttgtcc ttttaaaagc
    19321 tgatctatcg ttttatagaa ttcttcaaat ccaatttcat tgtatagaag tgaatttcct
    19381 atattccatt catttgctaa cttactccat atatcttcac ggatattatg atcaacatat
    19441 acagaatcaa tgccaattaa tttaatacct ctaagaataa acggtaatat attagcgtta
    19501 agtgaatttc ctgctacatt tccacataca gtagcaacac cttgataatt tagacgtttt
    19561 aaaccgtata atgttacatt actccccact gtatctaaga aataatcaaa aatacctttt
    19621 ttaagcggtt tattatcatc ttcaattatt attacttgtt ttgcacctaa tttttttgcg
    19681 atttctattt gcttttcttt tcttacgata gcagtgatat tttcatatcc aattttatgt
    19741 aaaatttgta tagcaacact gcccacacca cctgtagccc cagacactaa aatttcaggt
    19801 tgtgatttga tattcattcc atatttttct agttcaaaaa ttgataatgc tgccgtaaaa
    19861 ccggctgtgc catataccat agactcttta atagacattt cttggggaat aggaacaatc
    19921 cactctccag gcacttgtgc atattctgaa aatccacctg tatgtgtcac gccaacatca
    19981 taaccagtaa ctaatacatt atcgccttct ttaaacttat cattcgaact tgattcaaca
    20041 atacctgcaa aatctatacc aggaatcata ggataatctc taattacacc gcctttatat
    20101 tgtaaagcta gcatatcctt ataatttatt gaagagtata ccacttttac taatacatca
    20161 cccttcgata aatgagattc atcaactttt tctactttat aactaacatt tgatgcactt
    20221 tttctcacta ctaccgcatt gaacatttat tagccttctt tcacaattgt tttgtagaag
    20281 tatgtttttg ttgcaaaact attttcctac aaaacttatc atgatatgat aagcgagtca
    20341 atactaatga tttaagagag gttttagttg tggaattaga taattgtata aattatttgt
    20401 tgagtacttc tcagaataga gtttttaaac attttaaaag tttattaagt ccctataata
    20461 ttactccagc agaatatggt gttttgaatt gcttgattaa tagtaatttg aatacaccta
    20521 aagcgattgg taatacttta aatttagaac cttcaacaat atctggaata ttagataaga
    20581 tgtccaaaaa ggatctaata acacgtcaaa ctgataatga aaatagaaga actgtgctaa
    20641 taaacagtac aaataaagca aaagacttat ggccaacatt agaaaagaaa gcctatcaac
    20701 ttaataatca ttacttcgct aatttaacta atgaagaaac tgtagtgttt aaaaagatat
    20761 tactaaagat aaataaaact acgttttaat ttttacgtta taaaaaagtt gaagtgcgaa
    20821 ttataatcga gtaaatataa atgatagctt agcttaatta tatattaaag ccaactatac
    20881 ttttattccc gaaaaaccta ctatccaaat ttctaagata ctttagcctc tataataaac
    20941 atattgtaat ataatttatg tattatttag gtttacccta atcgaacaat aaaaaatact
    21001 tgtaaaatgc tattgtcact ttgcttgata tatgagaatt atttaacctt ataaatgaga
    21061 aaaaagcaac gcactttaaa taagatacgt tgctttttcg attgatgaac acctataatt
    21121 aaactattca tctattattt atgatttttt gtatatacaa tatttctagt ttgttaaaga
    21181 gaattaagaa aataaatctc gaaaataata aagggaaaat cagtttttga tatcaaaatt
    21241 atacatgtca acgataatac aaaatataat acaaactata agatgttatc agtatttatt
    21301 atgcatttag aatattaaaa ttccttcatt acactcttgg cggtttcact tatcaactta
    21361 tcatttggct tatcactttt attgtcttta ttcgtaaaaa tgactaaaac aataggttca
    21421 gattggccct taggataaac aaaagcaaca tcatttctag aagcatatgt tattgcttga
    21481 ccacttttat cagcaacctt atagtctttt ggaacaccat ctttaattaa agtgtctccg
    21541 tttttattat taaacattaa atcaagtaag aaatttttat tttttttgct taattttcca
    21601 tttgcgataa gtttatttaa agtcttgccg aaagcagcag gcgttgaagt atcttttttg
    21661 ctctttggtg aatagtaatt taattctatc tcatatctaa ctggatttgt tactttatct
    21721 cctagttctt ttagacgttg tttaactttt ttgattccac cgatttcttt tataatttta
    21781 ttgtttgctg tattatcact atatgtcatt gaagcctcaa taagttcttt taaagtgata
    21841 tcttttccta catatttttc taaaatagga gaataagcaa ctatatcatc tttgttaata
    21901 tgtacttttt tatttaactt attataaggt acttgttcta acaaaatagc actatttatc
    21961 gcttttgaag tcgaagcata ggcaaatctc ttatctgaat taaattttac ttccttacca
    22021 cttttagtat ttaaagcata aacaccaata tgagcattat attttttttc taaatcattt
    22081 aactctttgg catgtgaact gtttgaatta catgcactta aaactaaagc aattacaatt
    22141 aaaaatatta actttttcaa aataaaccct ccgatattac agttgtaatt tttataaatc
    22201 aataatatta caattgtaat attgatgtca attgtttatt ataaatattt gaaagaaggt
    22261 gtcaaaatgg ctaaattact aataatgagc gtagtaagct tttgttttat atttctattg
    22321 ttagtatttt ttaggtacat attaaaacgc tattttaatt atagtttaaa ttataaagtt
    22381 tggtatctaa ctatgcttgc tggattaatt ccttttatcc caattaaatt ctcttttata
    22441 aaatttaata atgtgaataa tcaagcgccc acagttgaaa gtaagtcaca cgatttgaac
    22501 cataacataa ataccaccaa acctattcaa gagttcacaa cagatatcca taagtttaat
    22561 tgggattcaa ttgataatat ctgcacagtt atttggatag ttttagttat tattttaagt
    22621 tttaaatttt tgaaagcctt attatatctt aaatatttaa agaaacagtc actttatcta
    22681 aacgaaaatg aaaaaaataa aatagatacg atacttttca accatcaata taaaaaaaat
    22741 attgtgattc gaaaagcaga ggctattcaa tctccaataa ctttttggta tgggaaatat
    22801 attattttga ttcctagttc atattttaaa agtgtaattg ataaaagact aaaatatata
    22861 atactgcatg aatatgctca tgctaaaaat agagatactt tacatttaat tatctttaat
    22921 atcttctcta ttattatgag ttacaatcca ttagtacata ttgtaaaaag aaagataatt
    22981 catgacaatg aagtagaagc cgatagattt gtccttaata atattaacaa aaatgaattt
    23041 aaaacttatg cggaatctat tatggactcc gtattaaaaa ccccattttc caacaaaaat
    23101 atattaagcc attcatttaa tggtaaaaaa tcattactca aaagtagatt aattaatata
    23161 aaagaagccg atctgaaaaa gcagtcaaaa ttaattctaa tttttatttg tatttttact
    23221 ttttttatca tgataattca aagccagttt ttaatggggc aatccttaac tgattataat
    23281 tataaaaagc ccttacaaag cgattaccaa attttagatg aaagtaaaaa ttttggttca
    23341 aatagtggat ctttcgttat gtacagcatg aagaaagaca aatactatat ttataatgaa
    23401 aaagaaagta gaaaaagata ttctcctgat tcaacttaca aaatttattt agcactgttt
    23461 ggacttgacc gtcatattat aagtgataaa aattcacgta tgtcatggaa tcataaacat
    23521 tatcttttcg agtcttggaa taaggaacaa gatttaaata cagcaatgca aaattcagtt
    23581 aattggtact tcgaacgtat tagtaatcaa ataccaaaga actatactgc ggctcaactc
    23641 aagcaattaa attatggtaa tgaaaatttg ggaagttata aaagctattg gatggaagat
    23701 agtttgaaaa tatctaatct tgaacaagta atagttttta aaaatatgat ggaacaaaat
    23761 aaccatttta gtaaaaaagc aaagaatcaa ttatcttctt cattattgat taagaaaaat
    23821 gaaaagtatg aactgtatgg gaaaacaggt acaggtatag taaacgggaa gtataataat
    23881 gggtggtttg taggttacgt aattacaaat catgataagt attattttgc tacacattta
    23941 tcagatggaa acccgtctgg gaaaaatgct gaattaataa gtgaaaaaat attaaaagga
    24001 atgggtgttt taaatgacca ataagcaagt tgaaatatct atggctgaat gggatgttat
    24061 gaatataata tgggataaaa aatcagtatc agctaatgaa attgtagttg aaattcaaaa
    24121 atataaagaa gttagtgata aaacgattag aacattaatc acaagactat ataaaaaaga
    24181 gattataaaa cgatacaaat cagaaaatat ttatttttac tcatcaaata ttaaagaaga
    24241 cgatattaaa atgaaaactg ctaaaacctt tcttaataaa ctgtatggag gggatatgaa
    24301 aagtttagtg ctgaattttg cgaaaaatga agaattaaat aacaaagaaa ttgaagaatt
    24361 gcgagacatt ttaaatgata ttagtaaaaa gtaattagag gtatgtttca aacataatac
    24421 atatgtaaac catacttgac tcttattaaa ttagttttgt taatgacatt taaaatatat
    24481 tattaaagat gagagtgtcc agaaaataac cattttctgt acactcttgt tttttgtcta
    24541 aataagtaag tattacatag aattatgtgt tcaaaaaccc aacaaaaaat ctatgttcac
    24601 aaaagacctc gtaatcaagt tatggtacac taaaggtgta tataggaggt ctgtattttg
    24661 aaaataggtt atgcaagagt ttcaactgga ttacaaaatt tgaatttaca ggaggatcga
    24721 ttaaatacat atggttgtga aaagatattt aatgaccata tgagtggttc aaaaagtaag
    24781 cgacctggtt tagataaagc aattgaattt gcgaggtcag gagatacgat tgttgtttgg
    24841 agattagata gactaggacg gaacatggag gatttaatca cgttagttaa tgaacttaac
    24901 gaacgaggtg tgagttttca tagtttagaa gaaaatataa cgatggataa atcaagttct
    24961 acaggacaat tattatttca tttattcgca gcatttgcag agtttgaacg taatttaatt
    25021 ttagagcgat catcagccgg tcgaattgca gcacgtgcta gaggccgata tggaggtaga
    25081 cctgaaaaat taaataaaca agatttaaac ttacttaaga cactttatga taatggtacg
    25141 ccaattaaaa caattgcaga gcagtggcaa gtttcacgta caactattta tcgttatctc
    25201 aataaattag aggcaaaaga gaataaaaac aagtagagca actaatctag cttactataa
    25261 tgaatctact aaataatttt atatatcatt aacatacaaa gactttgatt caatgtcact
    25321 cgatgtaaaa gagacgttct gacagcgtct aaaatctcat aatattttcc tgttatgaga
    25381 ttttaataat aacacaagaa aaaagcgtac aaattcgtac gcttttttaa tataatacct
    25441 gtttcactaa tgaacgtttt aagtatcttc atcattaact gaaactacag taataatact
    25501 cgtcaacaat attagtatag ttaaaataga aagacttagg actggcataa ccgaactaaa
    25561 attatatttg aaatataaaa gtgctaatga agagagaaat gtaaaaataa taaataccaa
    25621 agaccatttt tctaatttat tcattggctt cacctctttg aacttttata taatcatagg
    25681 agatattttt actacgattt ataaaaaata agaagataat cattattaaa gaaacgatta
    25741 atataatgtt gaatcctata gtatcaccta attcgtttac acctttgcct aatatcggag
    25801 atacaaagct ttgtattaat aatgaaagag atgcccatat agtaaatgag gttctgttgc
    25861 aaagttgaat ttatagtata attttaacaa aaaggagtct tctgtatgaa ctatttcaga
    25921 tataaacaat ttaacaagga tgttatcact gtagctgttg gctactatct aagatatgca
    25981 ttgagttatc gtgatatatc tgaaatatta agggaacgtg gtgtaaacgt tcatcattca
    26041 acggtctacc gttgggttca agaatatgcc ccaattttat atcaaatttg gaagaaaaag
    26101 cataaaaaag cttattacaa atggcgtatt gatgagacgt acatcaaaat aaaaggaaaa
    26161 tggagctatt tatatcgtgc cattgatgca gagggacata cattagatat ttggttgcgt
    26221 aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa acaatttggt
    26281 aaacctcaaa aggtaattac agatcaggca ccttcaacga aggtagcaat ggttaaagta
    26341 attaaagctt ttaaacttaa acctgactgc cattgtacat cgaaatatct gaataacctc
    26401 attgagcaag atcaccgtca tattaaagta agaaagacaa ggtatcaaag tatcaataca
    26461 gcaaagaata ctttaaaagg tattgagtgt atttacgctc tatataaaaa gaaccgcagg
    26521 tctcttcaga tctacggatt ttcgccatgc cacgaaatta gcatcatgct agcaagttaa
    26581 gcgaacactg acatgataaa ttagtggtta gctatatttt tttactttgc aacagaacca
    26641 gcatttgttt taatatttgt tccaaagagc catcatggct ttgacagagc tcttcttcta
    26701 tgcaaatgct tttaatccga tccacacgaa aattcctata ttcatttctt agcctgcaaa
    26761 accgattaag taccagttct gttcataaaa ccccagtgat ataggctcta tcattctgct
    26821 ttccggttct tgccctcctg atgcaggata ttgaattgat attacccttt tattgcagat
    26881 tgcagtctga attgctgcaa taacgttatc cgccaatgta tttttctgtc cagatgtgct
    26941 gtacacgtta atactgttct ccaactcctg tgcatagttt ttttcaccat gcttcaaaat
    27001 agatttgatt ttatacatag ctgaatcaaa atcctttata aatgattcat ctccatggca
    27061 atttaaaa
//
