LOCUS       NZ_CP146216            27332 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus aureus strain KWT 2016-Z4326 plasmid unnamed1,
            complete sequence.
ACCESSION   NZ_CP146216
VERSION     NZ_CP146216.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN39984694
            Assembly: GCF_037039325.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27332)
  AUTHORS   Monecke,S., Braun,S.D., Diezel,C., Reinicke,M. and Udo,E.
  TITLE     Sequencing a CC239-MRSA-III with a novel composite SCCmec element
            from Kuwait
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27332)
  AUTHORS   Monecke,S., Braun,S.D., Diezel,C., Reinicke,M. and Udo,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2024) Optisch-Molekulare Diagnostik und
            Systemtechnologien, Leibniz Institute of Photonic Technology (IPHT),
            Philosophenweg 7, Jena 07743, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 17-FEB-2023
            Assembly Method                   :: Flye v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 118x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_037039325.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 17:12:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,143
            CDSs (total)                      :: 3,060
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 73 of 118
            Pseudo Genes (incomplete)         :: 40 of 118
            Pseudo Genes (internal stop)      :: 19 of 118
            Pseudo Genes (multiple problems)  :: 14 of 118
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP146216.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27332
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="KWT 2016-Z4326"
                     /isolation_source="Medical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kuwait"
                     /collection_date="2016"
                     /genotype="ST239-MRSA-III"
     gene            join(<27138..27332,1..558)
                     /locus_tag="V8H03_RS15555"
                     /old_locus_tag="V8H03_15555"
                     /pseudo=""
     CDS             join(<27138..27332,1..558)
                     /locus_tag="V8H03_RS15555"
                     /old_locus_tag="V8H03_15555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163428.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /name="FAD-dependent oxidoreductase"
     gene            858..1265
                     /gene="merR"
                     /locus_tag="V8H03_RS15560"
                     /old_locus_tag="V8H03_15560"
     CDS             858..1265
                     /gene="merR"
                     /locus_tag="V8H03_RS15560"
                     /old_locus_tag="V8H03_15560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator MerR"
                     /protein_id="WP_000525462.1"
                     /translation="MGMKISELAKACDVNKETVRYYERKGLIAGPPRNESGYRIYSEET
                     ADRVRFIKRMKELDFSLKEIHLLFGVVDQDGERCKDMYAFTVQKTKEIERKVQGLLRIQ
                     RLLEELKEKCPDEKAMYTCPIIETLMGGPDK"
                     /name="merR"
     gene            1282..1767
                     /locus_tag="V8H03_RS15565"
                     /old_locus_tag="V8H03_15565"
     CDS             1282..1767
                     /locus_tag="V8H03_RS15565"
                     /old_locus_tag="V8H03_15565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746200.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_000746202.1"
                     /translation="MKKRISFTAIMTVLLIGLTACGAESDTANESKVQDIQGNPVSLPN
                     EKPTLIYFMATWCPSCIYNEEIFKEMHQLNPNDVQLITVSLDPNTDTKESLAKFKQDYG
                     GDWPHVLKNGKEIADTYGVKQLEEIVLVNSENEVFYRSVRPSFDDLKEALTQIGVEL"
                     /name="TlpA disulfide reductase family protein"
     gene            1764..2444
                     /locus_tag="V8H03_RS15570"
                     /old_locus_tag="V8H03_15570"
     CDS             1764..2444
                     /locus_tag="V8H03_RS15570"
                     /old_locus_tag="V8H03_15570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010351.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="WP_000010352.1"
                     /translation="MSFSFLFILTAGMVAAFNPCGIALLPSYISYLIGGETKDHSFRYA
                     IFKGLGLGGAMTTGFLTIFVLAGLLIGGLGSALTGIFPILSLVMGILIALLGLGMLFGK
                     HLPIKIGSFQVKPGKWSIYFYGIAYAVTSLGCTLPAFMLVVSASLNDNSVTAVIIKFII
                     YSLGMGIVVTAITMVSLISRQLVQKFLHNYMGSIQKIAAVVIFLSVLYMAYYWYFGSGG
                     ICTF"
                     /name="cytochrome c biogenesis protein CcdA"
     gene            2581..2919
                     /locus_tag="V8H03_RS15575"
                     /old_locus_tag="V8H03_15575"
     CDS             2581..2919
                     /locus_tag="V8H03_RS15575"
                     /old_locus_tag="V8H03_15575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000968575.1"
                     /translation="MMDENRSKGNRWGVWAFFGILLVPLLVPLLCCAGPILLVALGSTG
                     IGALFAGATGNWWLTGIFAALAIVMIALILSKLLKNKYNSPEGNGKTKNKTDCCTPPES
                     VDRKHETR"
                     /name="hypothetical protein"
     gene            2977..4620
                     /gene="merA"
                     /locus_tag="V8H03_RS15580"
                     /old_locus_tag="V8H03_15580"
     ARG             2978..4617
                     /name="merA"
                     /gene="merA"
                     /gene_name="mercury(II) reductase"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4702..5352
                     /gene="merB"
                     /locus_tag="V8H03_RS15585"
                     /old_locus_tag="V8H03_15585"
     ARG             4703..5349
                     /name="merB"
                     /gene="merB"
                     /gene_name="organomercurial lyase MerB"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(5547..6062)
                     /locus_tag="V8H03_RS15590"
                     /old_locus_tag="V8H03_15590"
     CDS             complement(5547..6062)
                     /locus_tag="V8H03_RS15590"
                     /old_locus_tag="V8H03_15590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000377078.1"
                     /translation="MDSHLNHILSYWQGPPLEGAKTIISKYGYPQEATMSRLIWYNSGP
                     WKRTIVYKDPVPHNFPTPHLDFLKQTIDYKVPVHLYDAIAAFDGSVYLDRTTGEASAKC
                     HEEAMNFLSLNLLNDIVTGKRDVQGAKAFYAQTAEQFTKYHITSPYTEGFLFPMQYNTA
                     DLGVTYFK"
                     /name="hypothetical protein"
     gene            complement(6181..6855)
                     /locus_tag="V8H03_RS15595"
                     /old_locus_tag="V8H03_15595"
     CDS             complement(6181..6855)
                     /locus_tag="V8H03_RS15595"
                     /old_locus_tag="V8H03_15595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105988.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(7092..7187)
                     /locus_tag="V8H03_RS15600"
                     /old_locus_tag="V8H03_15600"
     CDS             complement(7092..7187)
                     /locus_tag="V8H03_RS15600"
                     /old_locus_tag="V8H03_15600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000889979.1"
                     /translation="MLEILVHITTTVISGCIVALFTHWLRNRNDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(7665..8273)
                     /locus_tag="V8H03_RS15605"
                     /old_locus_tag="V8H03_15605"
     CDS             complement(7665..8273)
                     /locus_tag="V8H03_RS15605"
                     /old_locus_tag="V8H03_15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017432088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000793183.1"
                     /translation="MKNLKSFFIKNTLVLTSTALLFSSFEPVVHAAENKEVVKTVENDN
                     VEFNELLEGQEYIWEVLSRDDEGFKMFLDEQRAFNPNFDNDVLLAKQEGALNSSVFANN
                     SMTLNSNKPTPRGPIGATLKAIKALSPSLRHGGTAISWIIKPLSRKHAVLVKKYSRKMS
                     NAIDRLDKSTKSAVENAFVKAGIPRSDAKTLTYIVFLVI"
                     /name="hypothetical protein"
     gene            complement(9773..>9877)
                     /locus_tag="V8H03_RS15610"
                     /old_locus_tag="V8H03_15610"
                     /pseudo=""
     CDS             complement(9773..>9877)
                     /locus_tag="V8H03_RS15610"
                     /old_locus_tag="V8H03_15610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(9937..10611)
                     /locus_tag="V8H03_RS15615"
                     /old_locus_tag="V8H03_15615"
     CDS             complement(9937..10611)
                     /locus_tag="V8H03_RS15615"
                     /old_locus_tag="V8H03_15615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISSau6 family transposase"
                     /protein_id="WP_001105943.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITNQAPSTKVAMSKVIKDFKLTPNCHCNSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRFLQIYGFSPCRVISIML
                     AS"
                     /name="IS6-like element ISSau6 family transposase"
     gene            10648..11559
                     /locus_tag="V8H03_RS15620"
                     /old_locus_tag="V8H03_15620"
     CDS             10648..11559
                     /locus_tag="V8H03_RS15620"
                     /old_locus_tag="V8H03_15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_078065292.1"
                     /translation="MSNFATEPNVSYADILEILKIKKAYNVKQCGNVLEFKPTDEGYLK
                     LHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLSTKNAIDGDTL
                     EQSLKHLTKAFDRLSRYKKVKQNLVGFMRSTEVTVNKNDGSYNQHMHVLLCVENAYFRK
                     KENYITQEEWVNLWQKALQVDYRPVVNIKAIKPNQKGDKDIESAIKETSKYSVKSSDFL
                     TDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGNLINTSDEDKITDE
                     EAKAHSITAIWNFEKQNYYLRH"
                     /name="protein rep"
     gene            <12441..12542
                     /locus_tag="V8H03_RS15625"
                     /old_locus_tag="V8H03_15625"
                     /pseudo=""
     CDS             <12441..12542
                     /locus_tag="V8H03_RS15625"
                     /old_locus_tag="V8H03_15625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(12908..13255)
                     /locus_tag="V8H03_RS15630"
                     /old_locus_tag="V8H03_15630"
     CDS             complement(12908..13255)
                     /locus_tag="V8H03_RS15630"
                     /old_locus_tag="V8H03_15630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119692.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDGI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(13274..13890)
                     /gene="cadD"
                     /locus_tag="V8H03_RS15635"
                     /old_locus_tag="V8H03_15635"
                     /pseudo=""
     CDS             complement(13274..13890)
                     /gene="cadD"
                     /locus_tag="V8H03_RS15635"
                     /old_locus_tag="V8H03_15635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            complement(14071..14193)
                     /locus_tag="V8H03_RS15640"
                     /old_locus_tag="V8H03_15640"
     CDS             complement(14071..14193)
                     /locus_tag="V8H03_RS15640"
                     /old_locus_tag="V8H03_15640"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466482.1"
                     /translation="MFFYEDDDFDEMEEKYDYHEDKKIDDAFMPRKFIDVEKNP"
                     /name="hypothetical protein"
     gene            complement(14274..14462)
                     /locus_tag="V8H03_RS15645"
                     /old_locus_tag="V8H03_15645"
     CDS             complement(14274..14462)
                     /locus_tag="V8H03_RS15645"
                     /old_locus_tag="V8H03_15645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001030803.1"
                     /translation="MNKDTMLDKGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            complement(15042..15188)
                     /locus_tag="V8H03_RS15650"
                     /old_locus_tag="V8H03_15650"
     CDS             complement(15042..15188)
                     /locus_tag="V8H03_RS15650"
                     /old_locus_tag="V8H03_15650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001092935.1"
                     /translation="MNTKILTGMTGSSLERKINNFINDNQIEVIDIKFSSSVFYFGVMI
                     IYK"
                     /name="hypothetical protein"
     gene            complement(15193..15381)
                     /locus_tag="V8H03_RS15655"
                     /old_locus_tag="V8H03_15655"
     CDS             complement(15193..15381)
                     /locus_tag="V8H03_RS15655"
                     /old_locus_tag="V8H03_15655"
                     /inference="COORDINATES: protein motif:HMM:NF013603.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001559000.1"
                     /translation="MLSYGGLLKEKHKILNLDDAEDGNLINTSDEDKTTDEEEKAHSIT
                     AIWNFEKQNYYLKNLRS"
                     /name="hypothetical protein"
     gene            complement(15511..16455)
                     /locus_tag="V8H03_RS15660"
                     /old_locus_tag="V8H03_15660"
     CDS             complement(15511..16455)
                     /locus_tag="V8H03_RS15660"
                     /old_locus_tag="V8H03_15660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001132442.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDRNNNIYFIFSNKHLCEYLGYGEQKIIKLKKELVNFNLLTQERVGLN
                     KPNRLYLLKPNYDIEASLTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTELNNTN
                     YIENEDNDTYDMNDIISNTLINNNHHSNHTNHQKTEFNNDALKFQVLEELPQQLQDYLS
                     KFEIREIRIIKSVLLKGKKSFNTSHDTYYRLEDVEFEIVSVLKRFKAMLLQKNETVEAM
                     QGYLMQSIKAELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            16899..17669
                     /locus_tag="V8H03_RS15665"
                     /old_locus_tag="V8H03_15665"
     CDS             16899..17669
                     /locus_tag="V8H03_RS15665"
                     /old_locus_tag="V8H03_15665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000848988.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKNLNISFKKENGINYINDNDCLK
                     IIEKITKKERTMQNKESIKKERFNENTAEFEKHIYNNSNGFESLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEERQLN
                     YSFDTATNDRQSINPQEATFTEEYQNSNQQQKKIQPIEAELNHKGITKAKKDDSSNEDV
                     LKRDDKLSEEIESGPEDREVETPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(17985..18545)
                     /locus_tag="V8H03_RS15670"
                     /old_locus_tag="V8H03_15670"
     CDS             complement(17985..18545)
                     /locus_tag="V8H03_RS15670"
                     /old_locus_tag="V8H03_15670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(18750..20294)
                     /locus_tag="V8H03_RS15675"
                     /old_locus_tag="V8H03_15675"
     CDS             complement(18750..20294)
                     /locus_tag="V8H03_RS15675"
                     /old_locus_tag="V8H03_15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /protein_id="WP_000622776.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="quaternary ammonium compound efflux MFS transporter
                     QacA"
     gene            20472..21038
                     /gene="qacR"
                     /locus_tag="V8H03_RS15680"
                     /old_locus_tag="V8H03_15680"
     ARG             20473..21035
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(21171..21356)
                     /locus_tag="V8H03_RS15685"
                     /old_locus_tag="V8H03_15685"
     CDS             complement(21171..21356)
                     /locus_tag="V8H03_RS15685"
                     /old_locus_tag="V8H03_15685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(21361..21699)
                     /locus_tag="V8H03_RS15690"
                     /old_locus_tag="V8H03_15690"
     CDS             complement(21361..21699)
                     /locus_tag="V8H03_RS15690"
                     /old_locus_tag="V8H03_15690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(21945..22553)
                     /locus_tag="V8H03_RS15695"
                     /old_locus_tag="V8H03_15695"
     CDS             complement(21945..22553)
                     /locus_tag="V8H03_RS15695"
                     /old_locus_tag="V8H03_15695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(22679..23257)
                     /locus_tag="V8H03_RS15700"
                     /old_locus_tag="V8H03_15700"
     CDS             complement(22679..23257)
                     /locus_tag="V8H03_RS15700"
                     /old_locus_tag="V8H03_15700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690625.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNRLNNQENKDK"
                     /name="recombinase family protein"
     gene            23629..23997
                     /gene="cadC"
                     /locus_tag="V8H03_RS15705"
                     /old_locus_tag="V8H03_15705"
     ARG             23630..23994
                     /name="cadC"
                     /gene="cadC"
                     /gene_name="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM/LEAD/ZINC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            23990..26173
                     /gene="cadA"
                     /locus_tag="V8H03_RS15710"
                     /old_locus_tag="V8H03_15710"
     CDS             23990..26173
                     /gene="cadA"
                     /locus_tag="V8H03_RS15710"
                     /old_locus_tag="V8H03_15710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase CadA"
                     /protein_id="WP_338614548.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAKV
                     NFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFYKK
                     HSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDFDMK
                     TLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEALVMR
                     NGQEIMIHVDDIAVGDIMIVKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEV
                     FAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYTPIIMVI
                     AALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKG
                     GVYLEELGAIKAIAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALEYRSQHPLA
                     SAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKELNVSDFSLGF
                     ENNVKILQNQGKTAMIIGTEKTIIGVIAVADEVRETSKNVIQKLHQLGIKQTIMLTGDN
                     QGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVNDAPALAASTVGI
                     AMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVI
                     PGWLTLWIAILSDMGATILVALNSLRLMRVKDK"
                     /name="cadA"
     gene            complement(26408..27082)
                     /locus_tag="V8H03_RS15715"
                     /old_locus_tag="V8H03_15715"
     CDS             complement(26408..27082)
                     /locus_tag="V8H03_RS15715"
                     /old_locus_tag="V8H03_15715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105968.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWHIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     ARG             complement(18754..20294)
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          11615..11762
                     /name="MOBV"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          10672..11559
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.738"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(15204..15381)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.179"
                     /coverage="95.0"
                     /evalue="3.73e-65"
     Typing          complement(15512..16455)
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.577"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggccctgcct tagatatgaa tcttgaaaaa gggaatatag aaaggaaaaa acatggtgtc
       61 catgttaatg agtatttgca aagtgtaagt aacccgaatg tctatgcagc tggagatgct
      121 gcagcaacgg atggcttgcc cctcacacct gtagccagtg cagattctca tgtcgtagca
      181 tctaatttat tgaaagggaa cagcaaaaaa attgaatatc ccgtgattcc atctgctgta
      241 tttaccgtac ctaaaatggc atcggtaggt atgagcgagg aggaagccaa aaactctggc
      301 cggaatatta aagtaaagca gaaaaacatc tccgactggt ttacgtataa acggacaaat
      361 gaggactttg ctgcgtttaa agtgctgatt gacgaagatc atgatcaaat tgttggtgct
      421 catttgatta gtaatgaagc cgatgaactg attaatcatt ttgcaacagc cattcgtttt
      481 gggatttcaa ccaaagaatt gaaacaaatg atatttgcct atccaacggc agcttcggac
      541 attgcacaca tgttgtaagt ttgcgttttg tgagatgttt ataaaccact ttatcgtcta
      601 atcttgttat atgatcttag aatcaaaaag aaaataactt ttttgacagc cgcatttttc
      661 aacggaagaa tgtggcttct tggcgtgaag agcagatatc tttattctta aacttctaaa
      721 aaagcttatg tgaacacttg ataaataagg ttttttatct gacctatttt ataagattat
      781 tctataaaag aaaaaataat gtatgacttg accgtgtact atggtacagg gtttatactt
      841 tttattgagg tgacaatatg gggatgaaaa tcagtgaatt ggctaaagcg tgtgatgtga
      901 ataaagaaac cgttcggtat tacgagcgga aaggattgat agccgggcct cccagaaacg
      961 aatcagggta tcgaatatat tcagaggaaa cagcagatcg ggtacggttt attaaacgaa
     1021 tgaaggaatt ggatttctcg ctaaaggaaa tccacctgtt gtttggtgtg gttgatcaag
     1081 atggggagag atgtaaagat atgtacgcct ttaccgttca aaaaaccaaa gaaatcgagc
     1141 ggaaagtgca gggtttgtta cgaatccaac ggttattaga ggaattaaaa gaaaagtgtc
     1201 cagatgaaaa ggcgatgtat acctgtccta ttattgaaac gttaatggga gggcctgata
     1261 aataaatggg ggaagatttg aatgaaaaaa cgcatttcct tcaccgctat aatgacggtg
     1321 ttgttaatcg gtttaacagc ttgtggagca gaatctgata ccgcgaatga atcaaaggtt
     1381 caagacattc aaggaaatcc agtcagccta cctaatgaga aacccacact catttatttt
     1441 atggcaacct ggtgtccatc ttgtatatac aatgaggaaa tctttaagga aatgcatcaa
     1501 ctaaacccga acgatgttca attgatcaca gttagtttag accctaacac agatacaaaa
     1561 gaaagccttg cgaaatttaa acaggattat ggcggggatt ggccccatgt tttaaagaat
     1621 ggtaaagaaa ttgcggatac ctatggcgtc aaacaattgg aagagatcgt actggtcaat
     1681 tctgaaaatg aggtattcta tcgttctgtt cgaccgtcct ttgatgattt aaaagaagcg
     1741 ttgactcaaa taggagtgga attatgagtt tttcgtttct cttcattctg accgctggaa
     1801 tggttgcggc ctttaatcct tgtggtatcg ccttgcttcc ttcttatatc tcctatttaa
     1861 ttggaggcga aacaaaggat cattcgttcc gctatgcaat ttttaaagga ttagggcttg
     1921 gtggagcgat gaccacgggg tttttaacga tttttgtatt ggctggttta ttgataggag
     1981 gattgggaag cgcactaaca gggatttttc cgattctttc attggttatg ggtatactca
     2041 ttgctttatt ggggttgggc atgctattcg ggaagcattt gccgattaaa ataggatctt
     2101 ttcaagtcaa gccagggaaa tggtctatct atttttacgg aatagcctat gccgtgacat
     2161 cacttggttg taccttgcca gcctttatgt tggtggtctc tgcatcgctg aatgacaata
     2221 gcgtaacggc cgtgatcatc aagttcatca tctactccct tggtatggga attgtggtga
     2281 cagcgatcac gatggtctca ttgatttcac gacaattggt acagaagttt ctgcacaact
     2341 atatgggttc tatccaaaaa atagcagctg ttgtgatttt cctctccgtt ttgtacatgg
     2401 cttattactg gtatttcggt tctggtggca tttgtacatt ttaaaatcca accgatcagg
     2461 tgtaacaaaa aatagatgaa agatgtaaaa aagctaaacg aacaaatttc aagttaggct
     2521 ataggccatg tatgtacctt aaccaaagaa taaaattttt ttttagaaag agtggtgaga
     2581 atgatggatg agaatcgctc gaaaggtaac cgctggggtg tttgggcctt tttcggaata
     2641 ttattggttc ctttattggt tcctttactt tgttgcgcag gaccgattct ccttgttgca
     2701 ttagggagca caggtattgg tgccctcttt gctggtgcga caggaaattg gtggttgacc
     2761 ggcatttttg cagcattggc cattgttatg attgctctga tcctcagcaa gttgttgaag
     2821 aacaaataca attctcctga aggcaatgga aaaacaaaaa ataaaacgga ttgctgtacg
     2881 cctccagaga gcgtggatcg gaaacatgag acaagataaa tatgagataa atgtacagaa
     2941 ctgtctatca aactttaaat agaaagaggg attcaaatga ctcaaaattc atataaaata
     3001 cccattcaag gcatgacatg cacaggctgt gaagaacatg taaccgaagc attggaacaa
     3061 gccggagcta aagatgtttc ggccgatttc cgacgcggtg aggccatttt tgaactcagc
     3121 gatgatcaga tcgaaaaggc taagcaaaat atttcggcag ccggctatca acccggagag
     3181 gaagaaagcc agccctctga aaacagtgta gatttcaatc gggatggcga ttacgatctt
     3241 ctgattattg gttccggcgg tgcggcgttt tctgcagcta tcaaggccaa tgaaaacggg
     3301 gcgaaagtgg ccatggtaga acggggaacc gtcgggggga cctgcgttaa catcggttgt
     3361 gtaccgtcaa aaaccatgct tcgtgccggt gaaataaacg gtctcgccca aaacaatccg
     3421 tttaccggac ttcaaacgag taccggtgct gcggaccttg cccaattgac cgaacaaaaa
     3481 gatggattag tcagtcaaat gcgtcaagaa aaatatatag acttgatcga agaatatgga
     3541 tttgatctca ttcgtggcga ggcctcgttt atcgacgata agacgataca agtgaatgga
     3601 caaaacatca cgtctaaaag ctttttaatc gcaacggggg cttctccggc tgttccggaa
     3661 atcccgggaa tgaatgaggt tgattattta acaagtacat ccgcactcga attaaaagag
     3721 gttccacaac gattggcagt gatcggttct ggctatatcg cagcggaatt aggtcaaatg
     3781 tttcacaacc tcggaacaga agtgactctc atgcaaagaa gcgagcgtct gtttaaaacc
     3841 tacgatcctg aaatttccga agccatcgat gaatccttaa ctgagcaagg acttaacctg
     3901 atcactgggg tcacttatca aaaggttgag caaaacggta agtcgacaag catttatatt
     3961 gaagtgaacg gtcaagaaca agtcatcgaa gccgatcaag tcctcgtggc aacaggaaga
     4021 aagccgaaca cagagacttt aaaccttgaa tcagcaggtg tgaaaacagg gaaaaaaggc
     4081 gaagtgctga ccaatgaata tttgcaaacg tcgaataacc gaatatatgc cgcgggcgat
     4141 gtgaccctcg gtccgcaatt cgtttatgtt gcagcttatg aaggcgggat tgtggcaaat
     4201 aatgcgttgg gtctagcgaa acgcaaaatc gatcttcgct ttgttcccgg cgtaaccttc
     4261 accaatccat cgatcgccac agtcggcttg actgaacaac aggcaaaaga aaaaggttac
     4321 gatgtcaaaa catcggtcct tccgttggac gctgtaccgc gggccttagt caatcacgaa
     4381 acaacagggg tctataaact tgtagtcaac gcccaaaccc agaaattgat cggagcgcac
     4441 attgtgagtg aaaatgctgg agatgtgatt tatgcggcaa cgttagcggt tcaatttgga
     4501 ttgaccattg aagaccttac ggatagcttt gcgccttatt taacgatggc tgaaggatta
     4561 aagcttgcag ccttgacgtt tgataaagac gtatcgaaat tatcttgttg tgcaggctaa
     4621 tggttccttt tgattctaat gctatgttgc aggaggcact taaaacaatg aagtggagaa
     4681 aatataagga ggaataagct tatgaaaaat atttcagaat tctcagccca acttgatcaa
     4741 acttttgatc aaggggaagc cgtctctatg gagtggttat tccgtccgtt gctaaaaatg
     4801 ctggcggagg gcgatccagt ccccgttgag gacatcgcgg cggagaccgg gaagcccgtc
     4861 gaggaagtta agcaagtcct acagactcta cctagtgtgg aacttgatga gcagggccgt
     4921 gtcgtcggtt atggcctcac actgttccct accccccatc gcttcgaggt tgatgggaag
     4981 caactatatg catggtgcgc ccttgacaca cttatgttcc cagcactcat cggccggacg
     5041 gtccacatcg cttcgccttg tcacggcacc ggtaagtccg tccggttgac ggtggaaccg
     5101 gaccgcgttg taagcgtcga gccttcaaca gccgttgtct cgattgttac accagatgaa
     5161 atggcctcgg ttcggtcggc cttctgtaac gacgttcact ttttcagttc accgagtgca
     5221 gcccaagact ggcttaacca acaccctgag tcgagcgttt tgcccgttga agatgccttt
     5281 gaactgggtc gccatttggg agcgcgttat gaggagtcag gacctactaa tgggtcctgt
     5341 tgtaacattt aatcttaggc aattacgcct gcgtcaatct tggccttacg atgatgtcct
     5401 gtaaccgaag ctctatctag tgaaaccaat tttatgggaa accaaataaa taaaaagatc
     5461 aattgcttgt gcctatatcg gggagttaat aaagcgagaa agtggattct tgaatatagg
     5521 agtaaataag gtgccaaaat ggcaccttat ttaaaatatg taacgccaag gtctgccgta
     5581 ttatattgca ttggaaaaag aaaaccttct gtataaggag atgttatatg atatttggta
     5641 aactgttcgg cagtttgggc gtagaaagct tttgctcctt gaacatcacg tttgccagtt
     5701 acaatgtcat ttaacaagtt taaagataaa aaattcatcg cttcctcatg acactttgct
     5761 gatgcctcac ctgtagttcg atctaagtag acacttccat caaaagcggc aatcgcatca
     5821 tataagtgta cgggcacttt ataatcgatg gtctgcttaa ggaaatcaag gtgaggggta
     5881 gggaagttat gagggactgg atccttatat actatcgtgc gtttccatgg cccgctattg
     5941 taccaaatta atcgactcat tgttgcttcc tggggatatc catacttact aattatggtt
     6001 tttgcccctt ccaacggtgg tccctgccaa taggacaaaa tgtgatttaa atgactatcc
     6061 attgccatac ctcctaaaca tttgcctaaa agcattgtat gcccaataaa tgaattttag
     6121 gggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt cagtgttcgc
     6181 ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga tctgaagaga
     6241 cctgcggttc tttttatata gagtgtaaat acattcaata ccttttaaag tattctttgc
     6301 tgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat cttgctcaat
     6361 gaggttattc agatatttcg atgtacaatg acagtcaggt ttaagtttaa aagctttaat
     6421 tactttagcc attgctacct tcgttgaagg tgcctgatct gtaattacct tttgaggttt
     6481 accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat ctcgttgctt
     6541 acgcaaccaa atatctaatg tatgtccctc tgcatcaatg gcacgatata aatagctcca
     6601 ttttcctttt attttgatgt acgtctcatc aatacgccat ttgtaataag cttttttatg
     6661 ctttttcttc caaatttgat acaaaattgg ggcatattct tgaacccaac ggtagaccgt
     6721 tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac gataactcaa
     6781 tgcatatctt agatagtagc caacggctac agtgataaca tccttgttaa attgtttata
     6841 tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa attcaacttt
     6901 gcaacagaat cttttatagt atcaaagaaa attaataatt ctaattatag agttacactt
     6961 acgtttctta tgtttttgca ttcctctact aaccagtgtt ataatatgat taacaagaat
     7021 tctagcgtga atacaccaat cccctcacta ttgccgtagt gaggggattt tttaggtgtg
     7081 actatagtcg cctatttatc gttgcgattg cgtagccaat gcgtaaataa cgcaacaata
     7141 caaccactga tgactgtggt cgtgatgtga acaagaattt ctagcatgaa taacacctcc
     7201 tctctgcgtc taaatttgac gcctgagaga taggcgactc tattattata ccatctgtga
     7261 atatacaagc atatctactt ccgataagtc gtcttatgtt atataacttc gttttttata
     7321 gtatcaagac aaaagaagaa acgcagttca aaatcatcac ctaaattcat taatctaaag
     7381 aaaaaacggt gtaataaata gtgaatatta tagtctatta aagaatagat ttaaaaacac
     7441 tctaaaaggt gcattaaaga tttgtaaaac tttaatatat cctttttagg tgaaaactta
     7501 tgataattgt aggttctctc attatctatg attattaatt ttaactgtat ctagaaaatc
     7561 atcaccccaa tcacaaattg aaaatactac tttatcaaga taagaaaaaa gaaaaaaact
     7621 tgccctaaga ttttataaaa tcttagggca agtcagctca atatctaaat aactaaaaat
     7681 acaatataag ttaaagtttt cgcatcactt cttggtatac ctgctttaac aaaagcattt
     7741 tcaacagctg atttcgtaga cttatctaac ctatcaattg cattagacat ctttcttgaa
     7801 tattttttta ctagaacagc atgttttcta cttaatggtt taatgatcca agatatagca
     7861 gttccaccat gtctcaaaga aggtgataga gccttaatag cttttaaagt tgcaccgata
     7921 ggacctctag gagtaggctt atttgagttt aaagtcatag aattattagc aaatactgaa
     7981 gaatttaaag caccttcttg ttttgctagt aaaacatcat tatcaaaatt aggattaaaa
     8041 gctctttgct catctagaaa cattttaaat ccttcatcat ctctagataa aacttcccaa
     8101 atatattctt gtccttctaa caattcattg aattctacat tatcattttc tactgtttta
     8161 acaacttcct tattttctgc agcatgaact acaggttcaa aactagaaaa taataatgca
     8221 gtagatgtta gtaccaaagt atttttaata aaaaaacttt ttaaattctt catatgactt
     8281 ttatcctcca attataaatg ttaaaatttt ttattattaa atattatata cataaaagga
     8341 attaaattat tatgaaaaaa gtaaacaaag agtacttatt gaactttata attgtaacgt
     8401 tcttactcgg aataataatc atacctatat ccgtattagt attctcaata ccatttttta
     8461 gcataatagg tttccaatca ttagcagata atttaaatat aagttcttta ataacaataa
     8521 attggtattc aaataatatg ttttataaca ttggctatat tgcattattc tttatagtaa
     8581 cttatctaat atttattttt cttgaacttt ttataatatt tttacatata aaatacaaaa
     8641 agaaatttaa taatattatc ttattcatat tctttataac tgctaatatg atcgtattaa
     8701 acttaataat tttgaagatt ttctacaaca ttcatataaa cttatatttt caaattttca
     8761 tttattcttt atgcttctat cttttattta ctcataaaga gatttacaaa atatttgaag
     8821 aaaataaaag taaaaaataa aaaaataaaa aaattaatct ctcaaaaagt tttctcggca
     8881 taaaagtacc tctaactttt atacataaag tcatgagcat aagggaaagt gccaccactt
     8941 ttatattttg gcagacccat aacgtggtga actcggcagt gccgagttat ttttcctaga
     9001 aaaaaagtga catcactttt ttaactcata tgtataaaaa ccataacgtt atgtatacat
     9061 acaggttacg tatacatata ctttatgtat ataaaacata cacaaaagac atgcatcata
     9121 cacatcaatt tttttaaaaa tacatgtctt tttgatatat attttttttt gcgttttaag
     9181 aggtcattta gagcattctc taattttgag tacaaaaata cgtaatataa aaaaatcgtc
     9241 cttttaaaac ctttttagga cattttaaac acatttttat gatttggatc aatgtagaat
     9301 aaatgtcata aacgtataga aaaaatacgt cgtcatttct aagtacagat aaatttctga
     9361 tgcagtacta aattatgggg aaacctacct gtaaaaaata aaaagattac tatattttaa
     9421 ttttattttt tctgttcgtt ttttcgacac caggacgggc gatttttacg tactgcccat
     9481 ttacatgcaa atttaaaaat tagcaataaa tcgttccgaa tttgcatttt aaatgggcaa
     9541 acgtgccgtt tgatcacata gttcgtgtag cgacaaaaag agtataacga aagtataata
     9601 agcgtataaa aaaagtgtaa tgatagaaaa tagcattata cttttttagt cgttcatcgc
     9661 tcatcagaac aacaaataaa tttttaagaa ataaattttg agagttgacc acccacgttc
     9721 tccgtaaact acaaatgtgg gtggtcaact ctcaaaatat ttttatattt ttttattgtt
     9781 cttcttcggt aagttcgtga agttcacttg ccaggtactc tttctgattc caaatataat
     9841 aaatttggta aaggtattca gttggatcga tttcttggtt ctgttgcaaa gttaaaaaat
     9901 aagtgtctaa ccttatgttt aaaataatac ttcgtattaa ctagctagca tgatgctaat
     9961 tacacggcat ggcgaaaacc cgtagatctg aagaaatctg cggttctttt tatatagtcc
    10021 ataaatacat tcaatgcctt tgatcgtatt ctttgccgta ttgatacttt gataacttat
    10081 tttccttact ttgatatgac gatgatcttg ttcaatgaga ttatttaaat atttagagtt
    10141 acaatgacag ttgggggtaa gtttaaaatc tttaatcact ttggacattg ccaccttcgt
    10201 tgaaggggct tggtttgtaa ttatcatttg aggtttgcca aattgtttaa taagacgttt
    10261 aataaacgta tatgctgagt gattatctcg tttcttacgt aacgaaatat ctagtgtatg
    10321 gccatctgca tcaatagcgc gatataaata attccattgc cctttaattt tgatatacgt
    10381 ctcatctata tgccatttat aataagcttg cttatttttt ttcttccaaa tttgatacaa
    10441 aataggagca tattcctgta cccatcgata aattgttgaa tgatgaacat agatgcctcg
    10501 ttctctcaat atttcagata tatcacgata acttaatgca tatcttagat agtagccaac
    10561 ggctacagta atgacatctt tgtcaaattg cttatatctg aaataattca tcctctgcac
    10621 ctcatttttt gttgactatt atactatatt tctaactttg caacagaacc taatgtaagc
    10681 tatgcagata tacttgaaat tttaaaaata aaaaaggctt ataacgtaaa acaatgtggt
    10741 aacgtcttag aattcaagcc gaccgatgaa ggttatttga aattacataa gacgtggttt
    10801 tgtaaatcaa agctatgtcc agtttgtaat tggaggcgtg ctatgaaaaa tagttatcaa
    10861 gctcaaaaag tgattgaaga agtaattaag gaaaagccaa aagcacgttg gttgttttta
    10921 acactttcaa caaaaaatgc gatagatgga gatactttag aacaaagttt gaagcatcta
    10981 actaaagcat ttgataggtt gagtagatat aaaaaggtta aacaaaatct tgttggattt
    11041 atgcgttcaa cagaagttac cgttaataaa aatgacggta gttataatca gcatatgcac
    11101 gttttgttat gtgttgaaaa tgcatatttt agaaaaaaag agaattatat aactcaagaa
    11161 gaatgggtta atttatggca aaaagcatta caagttgatt atcgacctgt tgtaaatatt
    11221 aaagcaatta aacctaatca aaaaggcgat aaagatattg aatcggcaat caaagagaca
    11281 tcaaaatatt cggttaagtc atctgatttt ttaactgacg atgacgaaaa aaatcaagaa
    11341 attgtaagtg atttagaaaa aggtttatat cgaaaacgta tgttaagtta tggtggattg
    11401 cttaaacaaa agcataaaat tttaaactta gacgatgccg aagatggtaa tttaattaat
    11461 acaagtgatg aagataaaat aacagatgaa gaagcaaaag cacattcaat tacggcaatt
    11521 tggaattttg aaaagcaaaa ttattattta agacattagt gatgactgat gtctttttta
    11581 ttgatttttt gtaaaaaagt actgtcttat ttttgtgaca aatgctgtat gtagtgtcac
    11641 aaaagtgtga cactacagct ttttatgata tcactttaaa attacttaaa acccttggaa
    11701 tgtctggctt tgccagacct attatttttg aatgatagca aattctcctt atgctcttac
    11761 ggagttctta gagaaaaatt gaaatttctt gatttttgat aaaaacgccc tgcaggaatt
    11821 tagaaaaaca tggggaagtt ttaaaagatt ttatgctcat ttttaatttg catttaaatg
    11881 ggcagtgtta aaaaattagt cactggtttt gctgaaattt ttgtttgtga aattaccata
    11941 tatttatttg actcatattt gcgttttaag agcttgtata gatttttaag tagaagacta
    12001 taagatttac ctctaaatct ttaaaatacc ctcttaaaat tcaaaataaa ggtgtttata
    12061 atttgaataa gtcctgagat aaagtttttt aaaaggagtg gttttttgaa gaggtcttta
    12121 tttattttac aaattattct tggtattttt ttattgtttt ttatttataa gcaaatgaat
    12181 caaaatcatt tagatacttg gtttattctt tatacagtct tttttatatt tttttcatcg
    12241 tggtttgata aacattataa aaaaagttag acgacgcatt tatgccgaga aaatttattg
    12301 atgttgagaa gaacccttaa ctaaacttgc agacgaatgt cggcatagcg tgagctatta
    12361 agccgaccat tcgacaagtt ttgggattgt taagggttcc gaggctcaac gacaataaag
    12421 caattggaat aaaatacaca ggcattgaat gtatttatgg actatataaa aagaaccgca
    12481 gatctcttca gatctacggg ttttcgccat gccgtgtaat tagcatcatg ctagctagtt
    12541 aatacaaagt attactttaa acataaggtt agacacttat tttttaactt tgcaacagaa
    12601 ccttacatta tctattttct tttctctcca tgggcgttgt tttccacttt tcgtcatatc
    12661 ttttaacgtt ttattatctt gattttcggt tatacttcta gtagtattat attgcatata
    12721 aaaagaactc cagtattgat ttagattaga caccttaatc atattactgg agttttttta
    12781 tgtcaaattt tattttcccc aagcaaaaca gtatgaaacg ccgtcatatc aacgcttcaa
    12841 aaggatttta gaaaagaacg ttatttctat atagtatcaa gacaagaaga aactcgtttc
    12901 actcgtttca aaaaccctca tgatttttag agaaaaactc tcttattcca tcgtctttaa
    12961 taaaataata tgccatcttt ccatctttat aaaaatcaag tacctcattt ttatataaaa
    13021 gccttaaatg atgtgaagtt gaagcaacac tcattttcaa tatcaaagaa atatcacaaa
    13081 cacacaactc atcttcttta atcaaagata atatgatttt caatttcttc tcatcacaaa
    13141 ttttttctaa aatgttaagt aatttcttag atttatcatc ttctaaaaaa cttaaagcat
    13201 tgttaacttt atcctcatgt acacagatca catcacaagt attttcataa ctcatataaa
    13261 atcacaccct aaattaaaat ataaatccta aaattgtttg aatagtgtca ttttcaataa
    13321 taataaataa acctaaagct atataaataa tagccataat ccaacgacta aatttctcaa
    13381 caatttctcc aattcctggg atattagcta atttttgtgc agtaaacacc aagaagaaaa
    13441 ttaaaattaa aaagacaaac agagtaagta ataaattagt aacacttaat gtcacaaaat
    13501 acggaacaaa taaaccaata ttatcggcgc cacaacttgc tatcgtaaca attgcaaccg
    13561 taccaactaa tttagacaat cctttttcat tcagttcttt tttagctctc ttttctcctt
    13621 cacaatcaca taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc
    13681 taatatccac ttctctgaaa cataatttaa tacaaaagct aaaaacaaac taactaatat
    13741 taaaataata gaccctaaat attgaccaat ataaatatct ctatattctt ttttagtctt
    13801 tgctctagca aaaaatatta ataaaattac taataaatca aatgctgtag caatataaag
    13861 aatagcagca gtgacaaccg tttgaatcat acatacacct cattcaaaaa tatttttgaa
    13921 tgtattataa ctaatatttt taaataatca taggtgcttt attccaattg ctttattgac
    13981 gttgagcctc ggaaccccta acaatcccaa aacttgtcga atggtcggct taatagctca
    14041 cgctatgccg acattcgtct tcaagtttag ttaagggttc ttctcaacat caataaattt
    14101 tctcggcata aatgcgtcgt ctattttttt atcttcatga taatcatatt tttcttccat
    14161 ctcgtcaaaa tcatcatctt catagaaaaa caaaaagtaa gcaacaacac caataggaat
    14221 aaaaaatagt gtgaaaacaa gaagaaactc gtttcaaaat cccctcaaat attctaatta
    14281 ttctttttga aattcataac tttaacaacc aaataaatag catttattcc catcaaaata
    14341 acatacggaa ttaatatata taaattttcc aaatgagata taaaaattaa tccaagtaaa
    14401 aagaaaacat ttaaaatagt tgctataacg taacctttat ctaacattgt gtctttattc
    14461 aaaataaaaa ctccttttta aaaaacttta tcacaagact tactcaaatt ataaatacct
    14521 ttattttgaa ttttaagggg gtattttaaa gatttagggg taaatcatat agttttctat
    14581 ctaaaaccta tataatctct taaaacgcaa atatgaacca aatacatata tgctattttc
    14641 aaaaacaaaa ttttaaataa aaccaatgac tattttttta aacactgccc atttacatgc
    14701 aaattaaaag ttagcataaa atcctttaaa acttccccca tgtttttcta aattcctgca
    14761 agacattttt tatcaaaatc gagaattttt attttttctc taagaactcc gtaactccgt
    14821 aagagcataa gggaaatttg accccatgta tacatggggt atctggcaaa gccagacaat
    14881 tcaaagcttc aacaatattt ttatgtgggg tcataaaaag cttaagtgtc acacttttgt
    14941 gacacaatat attgcatttg tcacaaaaat aagccagtac ttttttataa aaaaacagta
    15001 aaaaaagaca tcagtcatca ctaatgtctt aaactcttta attatttata aataatcatt
    15061 accccaaaat aaaatacaga acttgaaaac ttaatatcaa tgacttcgat ttggttatca
    15121 ttaataaaat tattgatttt tcgttctaaa gaacttccag tcattccagt taaaatttta
    15181 gtgttcatat ttttaactcc ttaaattttt taaataataa ttttgctttt cgaaattcca
    15241 aattgctgta atcgaatgtg ctttttcttc ttcgtctgtc gttttatctt catcacttgt
    15301 attaatcaaa ttaccatctt cggcatcgtc taagtttaaa attttatgct tttctttaag
    15361 taatccacca taacttaaca tacgttttcg atacaaacct tttctagatc acttaaaatt
    15421 tcttgatttt tttcgtcgtc atcagttaaa aagtcagatg atttaacgga atattttgat
    15481 gtctctttga ttgttataaa atcatttgaa ttattgatta aagatattat attgtttcat
    15541 gtttttacgg cgcatataaa gggcatgtgt ttcttcaagt tcagctttaa tggattgcat
    15601 taaataacct tgcatagctt caacggtttc attcttttgt agcaacatcg ctttaaaacg
    15661 tttcaataca cttacaattt caaactcaac atcttctaaa cgataataag tatcatgtga
    15721 agtattaaat gactttttcc ctttgagtaa tacgctttta ataatccgaa tttctctaat
    15781 ttcaaattta cttaaatagt cttgaagttg ttgtggcaat tcttcgagta cttggaactt
    15841 aagggcgtca ttattaaatt cagttttttg atgatttgta tgattcgaat gatgattatt
    15901 atttattaaa gtattagata taatatcatt catatcatac gtatcattat cctcattttc
    15961 tatataatta gtattattta actcagtatc attagactgt gaatttggaa gttcttgacc
    16021 acttaaattc acagttctag aacttccaaa ttcattgttc tggaactgtg aatttggaag
    16081 ttccttggta agacttgctt caatatcata atttggtttt aataaatata atctatttgg
    16141 tttattaagg ccaacacgct cttgagttaa taaattaaaa tttactaact cttttttcaa
    16201 ttttatgatt ttttgttctc cataacctaa gtactcgcac aaatgtttat tactgaaaat
    16261 aaagtaaatg ttattatttc tatctaccca ttcattttgg atggataatt cgaaacgatc
    16321 ttttaataat gcatacataa ttttggcttc tgctgacatt ttcttaaaat atgcatcttc
    16381 gaacaaatat ttaggaagtt ggtaaaatct ttcagttttt acttgtgata aattgtattt
    16441 ctcaaaattg ggcataataa aaacctcatt tccacttttt ggatagaggt aataaaacaa
    16501 tttttacgta ggttatatgt tttgtacttg cacttatatg attagatata tataatacaa
    16561 gtatcaaaaa attatataaa cagacgaatg cgaatcgttt tattaccgag agtcgatgct
    16621 acgccaatag tatcgactct tttaatattc acaaagtaat attaacactt ttaagattgt
    16681 atataaagct ttttaagttt agttgaaaga acattgtaac tttaaaatga taaaaattca
    16741 ccactttagt acctaattag tcacctatag aaggttttaa cggctaatta ggtactaaag
    16801 tagtgaaata ggtagtaaat ttagatgtcg aaagatgaaa aaatatttgt taggtggtaa
    16861 aatttaggta ccaatttatg tacctaagga tgaatgttat gaaaactatt aaaatggttg
    16921 ctgatgaatt gaatgtaact aaacaaacta ttgttaataa tgctaaaaac ttaaatatat
    16981 cttttaaaaa agaaaatgga attaattata ttaatgataa tgattgttta aaaattatag
    17041 aaaagatcac taagaaagaa aggacaatgc aaaataaaga atcaataaaa aaagaaagat
    17101 ttaatgaaaa tactgcagag tttgaaaagc atatatacaa taattcaaat ggttttgagt
    17161 cattaaaaac aaaagtaaat gaattagaaa agcaaataga aatctttgaa actagagcta
    17221 aaaatgacga aaaatatatt gagaatttaa ctaaacaact agatcaacaa aatagcaatg
    17281 ttaatacatt aaataaactg ttggagaatc aacaaatatt agctttagaa agtaataaaa
    17341 agattcaaaa actagaaaac caattagaag aagaaagaca gcttaattac tcttttgata
    17401 cagcgactaa tgatagacaa agcattaatc cgcaagaagc aacttttact gaagaatatc
    17461 aaaatagcaa ccaacaacaa aagaaaatac aaccaataga agcagaatta aatcataagg
    17521 gcataactaa agcgaaaaag gatgacagtt caaacgaaga cgtattaaag agagatgata
    17581 aactatctga agaaatagag agtggacctg aggacaggga agtagaaaca cctaaaaagg
    17641 ggttttggag tcgtttgttt ggtagctaaa ataattaatt aggcactaaa agtttataac
    17701 ttttagtgcc ttttatatag tgagaacttc tggtaatcat cagttatgtt aaactctaac
    17761 aaaaactaaa ttatcagaag aattatctag ggtattaaac ataggtaaat caattttcta
    17821 tcgccaatag tataaacatc atccatatta atctgaagat agctacataa ttctttaaca
    17881 gcatagcctt tatttgtata aggcgccata aactctatta aatatggttt gttttgaggt
    17941 ttctatgttt aatcatttaa tttttcatta tataaatcga ataattataa aaagtcatca
    18001 tactttttat tttttaaaaa tatttgaaaa tttaatagta atccaattat aagatcaaat
    18061 atcattatca ttataatcaa ggcaactata atcactgtga cactcgttac ataacaagct
    18121 agtaatctcc agataaaatt gacattttca ccaattccat aacttaacat attacaaagt
    18181 agtaaaagaa taataatacc tatactgtaa attaaaattg tcagtgtata ttttttaata
    18241 actctattag gaaacaatag ttcatctatt aggttctttt tcaccagtat ctctcgttca
    18301 attctatctt tgtcacagat tttgatttta ctatttttta ttttttcctc taataaaata
    18361 acctcgaacg atctgctaat ttttaataaa tatgcaggaa aagctaatgt taagcataat
    18421 gtaattaatt catttacatt gttcatgtaa cttataaaat agatgaaagt tgctactagt
    18481 gctcctaaaa atatagttat attaagttct acatcaaata ttttaaaaat atctgctcta
    18541 ttcatcagtt aatcatcctt tcaaggttta ttaatactaa taaattatta gatataggta
    18601 tatcatatta ttaatttaag aaattgtctt ttataatttt acttaataat aaaaaagtag
    18661 aaccatttaa aattaatggt tctacttttt aactattact aattttaaaa ataaactaat
    18721 ctacaatatc taaaaatata tgtttagtac tatttttgtt tagttatatc aagtgatttg
    18781 ggaattaaca aatagacaac tattgaaatg ataatcatga taatcccacc tactaaagca
    18841 gttgctacaa aagcatcatt aaatgatgtt acagcctcgt ttgcaagctg ttttatcccc
    18901 gtagctttag ctacttcgac agcgcccact acagattctt cagctacatg agctaaatct
    18961 ccaactatac cttttgatga aaaagatgaa atatctaaaa atacacgata aagcatagaa
    19021 gataggctac caagtactgc tacaccaaaa acatttccaa ggtcatacat agactcttca
    19081 acagcagctg cattacctgc ttttgatgta ggtgtttcta acattattag agcagatgca
    19141 actgctagtg aagccatacc agctccaact aaaattaatg ctaaagccat tgtagaatat
    19201 gataatggat gaccaaagaa atacataata aacatgccaa tggctgcaat tccaattccg
    19261 gaaggtaaca ctattttcgg tccaaatcgc gccgctaatc cgggtgcaat tggtgcaaac
    19321 accatatctc ctattgccat aggtaatagg tataagccag ctttaaaagg agaaagttct
    19381 tccacaacct gtaaccattg tgaagctaat aacaaaacag atgccattgc aaacattgtc
    19441 ataaatgcag caattgtacc agctgaaaat gatctctttt taaaaagtct tacgtctaac
    19501 attggatcag aacttgataa attacgttta acaaatatca ctatcatggt aattgctaat
    19561 actattacaa cccatggaat aatatctgct agtccttctt ttgaaaattc tttgatactc
    19621 cataccagtc caatcatgcc tgcaattgat aaaattgtag aaggaatatc ccacgagtga
    19681 gacttttctt ttgataactt agactctggt aataaaaata aacctgctac aactgctatt
    19741 atcgcaaacg gtacattaat taaaaatgcc gagtgccatg aaaattgctc aagtaaagct
    19801 cctccgataa ttggtccaaa aacagcacct atcgatgaag cgattgacca tacagctaat
    19861 gcagtggccc tttctttagg gttttcaaaa attactctta tcattgaaag agtagttggc
    19921 attattaaag cacctgcaat accaagtaaa aatcgaatag ctattacgaa ctctgcactt
    19981 tctgcgaaaa atatagctaa tgaaacgagg ccaaataaag caaatccagt taataatgct
    20041 ttttttcttc cccatttatc agcaaaggca ctcaatggaa ttataaagcc agctaaaaca
    20101 agagagtata tatcaactat ccataactgt tgggtaccag aaggctctaa ctctcttact
    20161 aattccggta aagccataat taatattgtc atatccattg taacaacaaa caaactaaca
    20221 gctaatacta ctagtgcagt ccatcttttt tttgatgtca tcatatcagt agtttttgta
    20281 aaaaatgaaa tcatttaagt tccctccaat ccttatagac cgtgcgatcg gtctataagg
    20341 attataatct atttttttac atattacaac aaaaaatctt gcgaaattta aatggctgta
    20401 ttgtgttata caattattct ttgaattttt tgtgctatca ttgatagtac ttaatactca
    20461 ttaaaggcgt gatgaacttg aaagataaaa tactaggtgt cgcaaaggaa ttatttataa
    20521 aaaatggata taatgccact actactggag aaattgttaa attatcagaa agtagtaaag
    20581 ggaatcttta ttatcacttt aaaacaaaag aaaatctatt tttagaaatt ttaaatatag
    20641 aagaatctaa atggcaagaa cagtggaaaa aggaacaaat caaatgtaaa actaatagag
    20701 aaaaatttta tttatataat gaactatctt taacaaccga atactattat ccacttcaaa
    20761 acgcaataat tgaattttac actgaatatt ataaaactaa tagcattaat gaaaaaatga
    20821 ataaattaga aaacaaatat atagatgctt atcatgtaat ttttaaggag ggtaatttaa
    20881 atggcgaatg gtgtattaat gatgttaatg ctgttagtaa aatagcagca aacgctgtta
    20941 atggaattgt tacctttaca catgaacaaa atattaatga aagaattaaa cttatgaaca
    21001 agttctctca aattttttta aatggactta gtaaataatt atatatatat tcttgaaata
    21061 ccaataaata ttatttctaa attacgttcg ttattgagac aaaatttaat agtactacta
    21121 cacaaaaaga gagtgcgaat tcgcactctc tttttgtgat aaatgaatgg ttaagaaaat
    21181 aattcatcca cagttgtatc aaacaatctt gccaacttaa atgctaatgt caatgtagga
    21241 tcatatttat tgttttctat tgcattaata gtttgcctag acacttttaa ttctttactt
    21301 aaagtttctt gagaaattcc tttttgtttt ctatattctc taattctatt tttcattaat
    21361 ttaaccttta gatgtatatt ttttatttgt agtatagtaa ttaaacagca taagaaatag
    21421 tgctacaatt ataaagaaaa tttctggata ttgagaaaac caagatcctt caatacttgg
    21481 tgacaaacct gtaaatttaa gcactagtgt aaataacata caatatacaa tccaaataaa
    21541 acttttagcc agtatttcaa taaacatttt acgttgtctt tcatcgtatc gatcttgttg
    21601 tcctttttta tctaatgttt ctgaaggtaa atatttgtta gttatagccg tccataaaca
    21661 agaaaaaatt aaaataataa taaaaggaat taaattcatt ataacacctc ataaatgtaa
    21721 aaagtatttg acatttatga gtgtaaatat ttttgataca aatgtcaaat actttttaca
    21781 ttataatata ttttaaaaca ccttattagt aaaacaatta ctatatagaa agctgcgaac
    21841 tcgtactctt ttttcttgta taattattaa aatctcaatt caataatatg ttatggaatt
    21901 tgagacactg tgagagacgc tcatttgcat tgacaatcaa tttatcaaga taatccctta
    21961 tcatgtttaa ttctataaac tgtttgtctt gtgatattaa cttctttcgc aatcttacta
    22021 atcgctttgc cttcttctaa catttccacc acgcgatgat aaataacacg tttctgtggg
    22081 tctttagcat ttggtgaata aagtaaaggg cgccctttat atacgccttt ttccttcgca
    22141 acttgaatcc cttgcgcttg tcgacgttta ctttcatttc tctcttgttc tgaaaccatt
    22201 gctaatattt gaatgattaa atctttcata aacttatcca gtaatggatt gccaattact
    22261 tcattcatca taggtaagct ggtaatcatt aactgaacgt ctttttcttt taaataattc
    22321 acagtttcaa taatttcatc atagttacgt cctaaacgat caatagattc cacaacgaat
    22381 cgatctccca ttctgacaaa attgagtgct tcttgaaata caggtctatt ttccactgac
    22441 tttcccgact gtttctctgt aaagattttc tccacaccaa acgtctttaa attatccaat
    22501 tgtctttcta aattttgatc tatcgatgat actctcgcat aacctataat cattcatctt
    22561 cactccataa taaatataca ccctaatcat acgttttaat tgttataatt tcaacaattc
    22621 tttttgtatg gttagggtgt gtcctgtcta tttttatctt tcttaaaact tagtaatatt
    22681 atttatcttt attttcttga ttatttaacc tattgagata acgatagatt gtggtacgtg
    22741 aaactttcca ttgttctgca atagttttaa ttggtgttcc attatcataa agtgttttga
    22801 gtaactttaa atcttgttta tttaattttt cgggacgacc tccatagcgt cctctagcac
    22861 gagcggcaat tcgtcctgct gaagaacgtt ctaaaattaa gttgcgttca aactctgcaa
    22921 atgctgcgaa taaatgaaat aacaattgtc ctgtagaact tgatttatcc attgttatat
    22981 tttcttctaa actatgaaaa ctcacgcctc gattattaag ttcattaact aatgtgatta
    23041 aatcttccat attacgccct agtctatcta gtctccaaac aacaatcgta tctcctgccc
    23101 tcgcaaattc aatggcttta tctaaaccag gacgtttact ttttgatcca cttatgtggt
    23161 cgctaaatat cttttcacaa ccatattgat ttaattgatc ttcctgcaaa tttaaatttt
    23221 gtaaaccagt tgaaactctt gcataaccta ttttcaaaat acaaacctcc tatatacatc
    23281 ttcattgtat cataacttaa ttctaaccat atttatgaac atagattttc tgttgggtta
    23341 ttgaacacta aaatatgtat actcgctata tatatagaca taaaaagaga gtgtatagaa
    23401 aatggttatt ttctgtacac agttttaaat atcaaaaaca ttatttacat tttacgttta
    23461 agaactaatg gttaaaaatt tcattttgtc aaaaacgttc gtttttgaga ctagaatttt
    23521 atgccctact tacttctttt attttcattc aaatatttgc ttgcatgatg agtcgaaaat
    23581 ggttataata cactcaaata aatatttgaa tgaagatggg atgataatat gaaaaagaaa
    23641 gatacttgtg aaattttttg ttatgacgaa gaaaaggtta atcgaataca aggggattta
    23701 caaacagttg atatttctgg tgttagccaa attttaaagg ctattgccga tgaaaataga
    23761 gcaaaaatta cttacgctct gtgtcaggat gaagagttgt gtgtttgtga tatagcaaat
    23821 atcttaggtg ttacgatagc aaatgcatct catcatttac gtacgcttta taagcaaggg
    23881 gtggtcaact ttagaaaaga aggaaaacta gctttatatt ctttaggtga tgagcatatc
    23941 aggcagataa tgatgatcgc cctagcacat aagaaagaag tgaaggtcaa tgtctgaaca
    24001 aaaggttaaa ctaatggaag aagaaatgaa cgtctatcgg gtccaaggat ttacatgtgc
    24061 aaattgtgca ggaaagtttg agaaaaatgt taaaaagatt ccaggcgttc aggacgcaaa
    24121 agtaaacttt ggcgcttcta aaattgatgt atatggaaat gcatcggttg aagaacttga
    24181 aaaagcaggt gcttttgaga atctaaaagt atctcctgaa aaactagcga atcaaacgat
    24241 acaaagggtt aaagatgaca ctaaggctca taaagaagag aaaacaccat tttataaaaa
    24301 acatagtaca ttgctgtttg ccacactact aattgctttt ggttaccttt ctcactttgt
    24361 aaatggagaa gataacctcg taacttccat gttatttgta ggttcgattg taattggcgg
    24421 atattcacta tttaaagttg gttttcaaaa tttgatacgc tttgatttcg acatgaaaac
    24481 cctgatgacc gtagcagtta ttggagctgc catcattggt gaatgggcag aggcatccat
    24541 tgttgtcgtt ctctttgcaa tcagtgaagc acttgaacgt ttttctatgg atagagcaag
    24601 acagtccatt cgttcattga tggatattgc cccaaaagaa gcacttgtta tgcggaatgg
    24661 tcaggaaata atgatccatg tggacgatat tgccgtgggt gatattatga tcgtcaaacc
    24721 aggggagaaa attgccatgg atgggatcat tataaatggt gtgtcggctg tcaaccaggc
    24781 tgctataaca ggagaatctg tccctgttgc caaaacggta gatgatgaag tatttgcagg
    24841 tacgcttaac gaagagggac tacttgaagt aaaaatcacc aaatacgtag aggatacaac
    24901 tatctccaag attattcatc tggttgagga agcacaaggg gagcgcgctc cagcgcaagc
    24961 attcgtagat aaatttgcga aatattatac gccgatcatt atggttattg cggcgctcgt
    25021 tgcagtcgtt ccacctttat tctttggtgg aagttgggat acttgggttt atcaaggatt
    25081 agcggtactt gtagttggat gtccgtgtgc attagttatt tctactccaa tctcgattgt
    25141 ctcggcaatt ggaaatgcag ctaaaaaagg tgtgttgatt aaaggcggtg tctatctaga
    25201 agaattagga gccattaagg caatcgcatt tgataaaaca ggaacactga caaaaggtgt
    25261 accagtggta acagattttg aagtattaaa tgaccaagtg gaagaaaaag agctattctc
    25321 tatcattaca gctttagaat atcgttcaca acatccactt gcttcagcaa taatgaaaaa
    25381 ggcagagcaa gataatatcc cttattctaa tgtacaagtg gaagaattca cttcgattac
    25441 tgggcgaggt ataaaaggga ttgtaaacgg aactacttac tatattggaa gcccaaaact
    25501 tttcaaggaa ttaaatgttt ccgattttag ccttgggttt gaaaacaatg tgaaaatcct
    25561 acaaaaccaa ggaaaaacag ccatgattat tggaacggaa aaaacaatta tcggcgtaat
    25621 tgccgttgca gatgaggttc gtgaaacaag taaaaatgtg attcaaaaac ttcatcagtt
    25681 aggtatcaag caaacaatta tgctgacagg tgataatcaa ggtactgcaa atgcaatcgg
    25741 tacacatgta ggcgtttctg atattcagtc tgaattgatg ccacaggata aattagatta
    25801 tattaaaaaa atgcaatcgg agtatgataa tgtagctatg attggcgatg gcgttaatga
    25861 tgctccagca cttgctgcat ctactgttgg aattgcaatg ggcggtgctg gaacggatac
    25921 tgcaattgaa acagctgata ttgcattaat gggagatgat ttaagtaagc ttccatttgc
    25981 agtaagactc agtcgaaaaa ctttaaatat cattaaagct aacatcactt ttgctatcgg
    26041 aattaaaata attgccttac tattagttat cccgggatgg ttaacccttt ggatagcgat
    26101 tctttccgat atgggagcta ctattttggt agcattaaat agtttacgac tgatgagagt
    26161 gaaggataaa taggtagaaa acagaatagt aaggtcacgc tgtgcgcaat tcaagggggg
    26221 cttttcaatt tgaagaaaag tcctacccct aaaatataaa atattggaga tggaaaaatg
    26281 atcgcaacga tacttacagc agctgcggta tatgtagcaa caggaattga tatctcgtta
    26341 tattaattct ggttctgttg caaagtaaaa atatagctaa ccactaattt atcatgtcag
    26401 tgttcgctta acttgctagc atgatgctaa tttcgtggca tggcgaaaat ccgtagatct
    26461 gaagagacct gcggttcttt ttatatagag tgtaaataca ttcaatacct tttaaagtat
    26521 tctttgctgt attgatactt tgataccttg tctttcttac tttaatatga cggtgatctt
    26581 gctcaatgag gttattcaga tatttcgatg tacaatgaca gtcaggttta agtttaaaag
    26641 ctttaattac tttagccatt gctaccttcg ttgaaggtgc ctgatctgta attacctttt
    26701 gaggtttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa tgattatctc
    26761 gttgcttacg caaccaaata tctaatgtat gtccctctgc atcaatggca cgatataaat
    26821 agctccattt tccttttatt ttgatgtacg tctcatcaat atgccatttg taataagctt
    26881 ttttatgctt tttcttccaa atttgataca aaattggggc atattcttga acccaacggt
    26941 agaccgttga atgatgaacg tttacaccac gttcccttaa tatttcagat atatcacgat
    27001 aactcaatgc atatcttaga tagtagccaa cggctacagt gataacatcc ttgttaaatt
    27061 gtttatatct gaaatagttc atacagaaga ttcctttttg ttaaaattat actataaatt
    27121 caactttgca acagaaccag aattttgata tagatcttgt agatatcctt ttagaaaagt
    27181 cgaaagagat tggcatacag gtacatcttc aacattccgt tgaatccatt gaaaaagaac
    27241 aaggaaagtt tcatgtgtac gctcgaaaaa aagaggatat aacgcggttt gaagcagaca
    27301 ttgttattca tggtgctgga cggggccctg cc
//
