LOCUS       NZ_CP145161             7823 bp    DNA     circular CON 05-APR-2024
DEFINITION  Raoultella ornithinolytica strain CAVp363 plasmid pCAVP363-7823,
            complete sequence.
ACCESSION   NZ_CP145161
VERSION     NZ_CP145161.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN22837213
            Assembly: GCF_036786065.1
KEYWORDS    RefSeq.
SOURCE      Raoultella ornithinolytica
  ORGANISM  Raoultella ornithinolytica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Raoultella.
REFERENCE   1  (bases 1 to 7823)
  AUTHORS   Sheppard,A.E., Barry,K.E., Parikh,H.I., Vegesana,K., Sebra,R.,
            George,S., Sanderson,N.D., Stoesser,N., Eyre,D.W., Crook,D.W.,
            Walker,A.S. and Mathers,A.J.
  TITLE     Tn5403 promotes plasmid rearrangements and degradation of the
            Klebsiella pneumoniae carbapenemase (KPC) transposon Tn4401
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7823)
  AUTHORS   Sheppard,A.E., Barry,K.E., Parikh,H.I., Vegesana,K., Sebra,R.,
            George,S., Sanderson,N.D., Stoesser,N., Eyre,D.W., Crook,D.W.,
            Walker,A.S. and Mathers,A.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2024) Biological Sciences, University of Adelaide,
            Victoria Drive, Adelaide 5005, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 18x and 84x
            Sequencing Technology             :: Oxford Nanopore and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_036786065.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 15:59:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,742
            CDSs (total)                      :: 5,620
            Genes (coding)                    :: 5,447
            CDSs (with protein)               :: 5,447
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 55 of 173
            Pseudo Genes (incomplete)         :: 129 of 173
            Pseudo Genes (internal stop)      :: 24 of 173
            Pseudo Genes (multiple problems)  :: 33 of 173
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP145161.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7823
                     /organism="Raoultella ornithinolytica"
                     /mol_type="genomic DNA"
                     /strain="CAVp363"
                     /host="Homo sapiens"
                     /db_xref="taxon:54291"
                     /plasmid="pCAVP363-7823"
                     /geo_loc_name="USA:Virginia"
                     /lat_lon="38.14 N 78.45 W"
                     /collection_date="2016-12-01"
                     /collected_by="Clinical Microbiology University of Virginia
                     Health System"
     gene            complement(181..315)
                     /locus_tag="LMH34_RS28650"
                     /old_locus_tag="LMH34_28650"
     CDS             complement(181..315)
                     /locus_tag="LMH34_RS28650"
                     /old_locus_tag="LMH34_28650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724569.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_071988542.1"
                     /translation="MNGGIILFLIAMPLLVSCQANYIRDVQGGSVAPSASTTISGTSS"
                     /name="colicin release lysis protein"
     gene            complement(340..846)
                     /locus_tag="LMH34_RS28655"
                     /old_locus_tag="LMH34_28655"
     CDS             complement(340..846)
                     /locus_tag="LMH34_RS28655"
                     /old_locus_tag="LMH34_28655"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032724462.1"
                     /translation="MMRFWAFGFLCFLCVGEASADVKVFFAPKSTTYETNTSAEIKKYL
                     EDLVGGKVVDLSDNPKAVNKSLGEYLKKIKGKTSVFFGRNEMSKYNGTVCKISITTGNT
                     APSDPILTQVFTLGTLADNNSEPCRELNNKLMSVVSRDDVFKYPAVVKDYGMLSMDMIF
                     YFNNN"
                     /name="hypothetical protein"
     gene            1690..2235
                     /locus_tag="LMH34_RS28660"
                     /old_locus_tag="LMH34_28660"
     CDS             1690..2235
                     /locus_tag="LMH34_RS28660"
                     /old_locus_tag="LMH34_28660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_049245975.1"
                     /translation="MPLPERMKPARVTRKQMKELISQLNGILDHIDNGMDENNEELKQM
                     MADWNAKVVMPCGFSDFRDFSSWTSALDFTRMALNQEKYLDDFTWTELNDVINFIRKAE
                     GSASDHSYALQLLEINFKANPLDLIYHPDCWFNDEALFHARLTTEEIGGYLMKKSGRWL
                     NDAPDIQLVYAIPQDVYD"
                     /name="hypothetical protein"
     gene            complement(2299..5196)
                     /locus_tag="LMH34_RS28665"
                     /old_locus_tag="LMH34_28665"
     CDS             complement(2299..5196)
                     /locus_tag="LMH34_RS28665"
                     /old_locus_tag="LMH34_28665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            5291..5896
                     /locus_tag="LMH34_RS28670"
                     /old_locus_tag="LMH34_28670"
     CDS             5291..5896
                     /locus_tag="LMH34_RS28670"
                     /old_locus_tag="LMH34_28670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            complement(6653..7075)
                     /locus_tag="LMH34_RS28675"
                     /old_locus_tag="LMH34_28675"
     CDS             complement(6653..7075)
                     /locus_tag="LMH34_RS28675"
                     /old_locus_tag="LMH34_28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_195711771.1"
                     /translation="MARVSISEAARLVKVSRPTIYKMLNSGKLSYTSVVKQGKDIKVID
                     TSELIRVFGSLDGVIDSVKYDVNIDAKSTEVNNQGLHDLQHRIALLEAENDGLKGAVKA
                     RDEHIDSLRQAMQLLEHKHGHSSQDHSPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(7075..7266)
                     /locus_tag="LMH34_RS28680"
                     /old_locus_tag="LMH34_28680"
     CDS             complement(7075..7266)
                     /locus_tag="LMH34_RS28680"
                     /old_locus_tag="LMH34_28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_195711769.1"
                     /translation="MTKQQTTALNMAKFIQNQSLLLLGKLNELDLDAEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     Typing          6..175
                     /name="rep_cluster_2358"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="85.057"
                     /coverage="88.0"
                     /evalue="1.1999999999999999e-39"
     Typing          7314..7793
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.909"
                     /coverage="92.0"
                     /evalue="0.0"
ORIGIN
        1 cggttaaggc taaactaaac gaacagtttt ggtgactgcg ctcctctaac tagccagtta
       61 cctcggttca gaaacttgcc ggtttccgat ccttcgaaaa aaccaccttg ccgggtggtt
      121 ttttcgttta cagagcaaga gattacgatg aacgataaag gatcacaaga agatccgtta
      181 ctaagagcta gtcccactta tcgtagtaga tgccgagggg gccaccgatc ccccttgaac
      241 atctctgata tagtttgctt gacatgagac tagcaatggc attgcaataa gaaataaaat
      301 tattccgccg ttcatgatac accaccaaaa taaaacaaat taattattat taaaataaaa
      361 tatcatgtcc atagatagca tcccataatc tttaactact gccggatatt taaagacatc
      421 atccctacta actacagaca ttagtttgtt atttaattca cgacaaggtt ctgagttatt
      481 atcagccaac gttccaagtg taaacacctg agttaagata ggatctgacg gggcagtatt
      541 tcctgtcgta atggatatct tacaaacggt cccattatac ttgctcattt cattgcgacc
      601 aaaaaaaaca gaagtctttc cctttatttt tttcagatac tcacccagag atttatttac
      661 cgctttaggg ttgtcactta aatccacaac tttaccacca actagatctt ctaaatattt
      721 tttaatctca gcagatgtgt tggtttcata tgttgtagat tttggagcaa aaaaaacttt
      781 aacgtcagca gatgcctcac caacacataa aaaacataaa aaaccaaaag cccaaaaccg
      841 catcataacc ttacctcata gaagacatta aatgcattat tgttaataag cttaaaaaaa
      901 atccttgctc ccatcttaaa tggatgggag caacaaattt ataccactac cgattatagc
      961 gcaactgaac gtaggtatct ttattccttt tgtcacctct ttgttttatt gttcgatgac
     1021 tctcatcagc tgcggcattc caatcaccac gatttactgc atcattaaac ttaacaaatt
     1081 ccttcttaag ctttggaaca ccaaggttaa accccatatc taccaatgca gttttccgtg
     1141 gatctgagaa atcattataa ccagggtaaa gactgcgtaa cccagtctct gttgtttgga
     1201 catctttaat acactgccca attacatctg catttgaaag atgaatgctt tgctgttctt
     1261 ttgggttttt cttataagca tcggcatggt tctagcgaac agatgtcacc gacagaatat
     1321 gaaaaccagt attatcaacg gctcggaagt gtctagatta tccgtggcga ttcaatccgg
     1381 cgtgcggttt attgcttcag gacagttatc cggaggctgt tattagttct ctgccacgcc
     1441 aaactagtgt atataaaaac atgtgtttat atacagtagt ttgatactac tcttgacatg
     1501 ccagctctgt caatatgcag acgtcaacaa tatttttatt tattttcaat cggttaaaag
     1561 ttacggcaga ggtaaatctg aggcagaatg cggatcatca gaaagaaaaa aaacgatttg
     1621 tgctctgatt catagcccga tagattactc agttcccccg agtgcacgat aaaaaagaga
     1681 gtatttctga tgccattacc tgagcgaatg aaacccgcac gggtcacccg taaacagatg
     1741 aaagaactga tcagtcagct gaatggcatt ctcgatcaca tcgataacgg gatggacgaa
     1801 aacaatgaag aactaaaaca gatgatggca gactggaatg caaaggtcgt catgccctgc
     1861 gggttctctg attttcgtga tttttcatcc tggacaagtg cactagattt caccaggatg
     1921 gcgcttaatc aggaaaaata cctcgatgac tttacatgga cagaactgaa cgacgttatc
     1981 aacttcatac gcaaagcaga aggtagtgca tctgaccaca gctatgcact ccagttactg
     2041 gagattaatt tcaaggcaaa cccactggat ctcatctatc accctgactg ctggttcaat
     2101 gatgaagcat tgtttcatgc ccggctgact accgaagaaa ttggtggcta cttaatgaaa
     2161 aaatcaggtc gatggctcaa cgatgcaccg gatatccaac tggtgtatgc catcccccag
     2221 gatgtttatg attaaccaag tcaccattta ccataatccc ttaatggggt cggttccggc
     2281 tgagggcgaa atgacaccct aagctttcgg ttccttgggc caaagatatt cgccagtcag
     2341 tagaatgtgc gcccagccca atggggatat gtggggaaga aattcagggg gaacatccaa
     2401 cccttcgttc cgccgctccg tgacggcatg accaagatgg acggtattcc agtaaatgat
     2461 caccgcagtc aataaattga gcccagcgat tcggtagtgc tgcccctctg tcgtgcgatc
     2521 gcgaatttcc ccctgcctcc cgatacggag cgcatttttg agcgcatggt gggcctctcc
     2581 cttgttaaga ccgatctgag cacgccgctg catgtccgta tccaggatcc actcaataat
     2641 gaaaagggtc cgttcaatac gaccaacttc acgaagcgca actgcaaggt tgttttgtcg
     2701 tgggtaagaa gcgagcttgc gcaggagttg gctgggcctg attttgccag cggtcatcgt
     2761 cgcggcacaa cggaaaatat caggccagtt cgcaacgata agatcctccc gggcttttcc
     2821 acctaccaac ttgcgtaact ccctgggggt cgtatcggga ttaaatacgt acaaccgctt
     2881 cgatggcaga tccctgattc gcagaacgag attgtagccg agcaggctac tggctccgaa
     2941 caaatggtcg gtgaatcctg ctgtatcggc atactgttcg cgaacatggc gaccgacctc
     3001 gttcatcagt agtccatcga gaatatacgg tgcctcgctc acggtcgccg ggatcgactg
     3061 acaagcgaat ggcgcgaact ggtcgcttac gtgagtatac gctttgaggc cgggaacaga
     3121 accatatttg gcattgacca tgttcatggc ttcgccatgc cgcgctgtcg ggaaaaactg
     3181 accatcgctc gatgctgacg tgcccatccc ccagacgcgt gacatcggca gtttaccctg
     3241 cgcggccacc acaattgcca atgcctggtt catggcttcg ctttcaacat gccagcgggc
     3301 aaggcgtgag agctgccagt aatcatgcgt gtttgtagct tccgccatct tacgcaggcc
     3361 cagattgagc ccttcagcga gcaggacgtt gagcagaccg atccggtcgc gacatggagc
     3421 cccggttctc agatgggtaa acgcatctgt gaaaccaagg gctgcatcaa cttcaagcag
     3481 catgtcggta atccgaacgg acggcattcg gcgatacaga tccagtatga gtgcctcggc
     3541 accatccggc acgtctgctg tcaacctgtc gatccgcaac gttccatctt ctatgctacc
     3601 gtgcggaata gtgccgttac gggcagcccg ggccagccgc ttaagagcga tcgtgagtcg
     3661 cgcctttctg tctgccagcc aatcctgtgg gttggaaggc acggccagtt ttgcattttc
     3721 ctgcgccgcg atcatcggca ccagtacctg cttgaggtca ccatagcggc gcgaatgagc
     3781 gagccagaca tctccggaac gaaaagcatc ccggaggtga aagagtacag ccacttccca
     3841 aagacgggta tctccttttt cctgagctcg taaatgacgg ttccatttgg agctgggccg
     3901 caggaaacgc ctttctggcg atgcaacacc tttcatctct ccgatcgaca aagctgctgc
     3961 taccaatggt ccggcgaccg gcgcggcttc gagcttcaga cagcgcaaca tgcggggcgc
     4021 ataacgacga aagcgatggt atccctgccc gacatatgca agaggctcat cggctagcgt
     4081 gttgctgagt tgagtccctg tcgctaccag ttgagcgagc cggtcccatg caaccgaact
     4141 ggcgacagcc atctccagcg gggttccgtc actgcgggcc tcaagcaacg aagctcccag
     4201 cgcggtgaag gtacggatcg tatccgtgag tgtggcttta gagccggaaa ttgtttcgtc
     4261 atgctggcgc ttcgcttccc gccaggtttt tcctacgatc ctgtcatggg tttcgactat
     4321 ggcatcagca atcgccgctt cccactccac aacacagacg gcaaggatcg cccagcggcg
     4381 gtccgaagtg atgtcacgca aaccgtcggt gaagtagcgt tcaccctgcc gacgcagccg
     4441 ggcaatgcga tgggcaggta tgctggccaa agcactatga ttgatattca gggtacgcag
     4501 aaattcgagc ctgtcgagca aacggttagc agcagccgag ttgttaccaa cctcgaagtt
     4561 gcgaagccag atgaaacgac tgatattgcc ggcgagcatt tcactcagaa gtttgtccag
     4621 gtgatcgcga acatccgctg ttaaattttc cgcaatccgc gtttcaatcc gccgctcagc
     4681 ggcgaccaga gcatccgcgc acaagcgctc gattgtcgat actgcgggca gaatggtgga
     4741 agtttcccga caccgcacaa taaaacgatg agcaagatcc tcgtttgatc tggcatcttc
     4801 ggcctggccg aaagtccact cccgcagatc acgggcacca cggcccgtga aggtcttgta
     4861 gccgtaaatt tcgcgcagcg tgtccatgtg ctgctgacgg gtttggcgcc gtgtggcata
     4921 agtgagaagc gcatcagccg gaactccaag ctgagcaccg acgaaggaaa ggacttcacg
     4981 cgggatcatc tcaccaggag ccagtgcacg gcccggatat cgtaaggcac aaagttgcag
     5041 ggcaaagcca atcctgtttt ccggtctgcg gcgctgccta atgttttcca ggtcatcatc
     5101 gcccagcgtg tagaacttca gtagcgacag ttcgtccgtg ggcagatcga acagcgctgc
     5161 tcgctgccgt tcggtgaaaa tatggcgtcg tgacatacaa attcgtccct tttgaagtat
     5221 agtctgtttt ggacaacagc cagcccatat aaatcagggc gttccgatac aaaaatccag
     5281 gagggttcaa ttgggacatc gtgccgccat ttactgccgg gtttcaacag cggatcagtc
     5341 ttgtgaacgc caggaatttg atctgcgagc cttcgccggc cgtgccggct acgacgtggt
     5401 gggaatattt aaggaaacag gttcaggaac taaactcgac cgggccgagc gaaagaaagt
     5461 cctggcgctt gcccagtcca gacaaattga tgcaatcctg gtcactgagc tttcccggtg
     5521 ggggcgctcg acgctcgatc tgctcaatac gctacgtgaa ctggagaact ggaaggtttc
     5581 cgtgatagcc atgaatggaa tggcgttcga tctttcgtcg ccgtatggac gaatgctggc
     5641 gacgtttctt tccggcattg cggagtttga gcgggatctc atcagcgagc gggtcaagtc
     5701 aggccttgct gttgcgaagg cacgtggtaa gaggcttggt cgtcaggccg gagtgcgacc
     5761 aaaatcagac cgacttttgc ctaaggtggt tgcgatgagg gccgagggac gcagctatcg
     5821 ctggatcgca cgcgagctcg gtatcagcaa gaataccgtc gctgacatcg tgcaacgaca
     5881 cagagctaac gcttagggtg tcatttcgcc ctcagccgga accgacccct taattgtacg
     5941 caccgctaaa acggcctcat ggcgtttctg gcaggaaacc ggcaaaacag gcaacaaacc
     6001 acccgaaaac ctgccagaaa cgcgctggct ctgtttttac gacatgcatg agtatgcgcg
     6061 caagtgcata gcgcggaaat tcacgccgtg cagccaggga aagtcctgtt tctgacgttc
     6121 ttctcctccg aaaacggtga acggggacgt aatttattgc gtggccgtga ggcgttgccg
     6181 gcgcagccgg aaaaccggtt ttcagcacgt tcaggaatcg ggttcgtcga cggccggcaa
     6241 tcacgttatg gcaagtcgcc ggacgactca ccacacgatt caccggcgac tcttcactag
     6301 agtcgtacct agagtcgcca cgactaaaaa acaaccaaac ggggagtcgg gtctagagtc
     6361 gggtcgttat taactcattg tttttatagt cctgagtcgt ccccgactct atgacgactc
     6421 gccggggact ctatgacgac tcgtcataga gtcggttcta tataaataaa atttaaaaaa
     6481 cgaaatctcc ttaacgtaac caactgatat taaatacaaa tcttcaaaat tttaattttg
     6541 cgtggggtgt gggtattttt agtggtgagg agcgttcaga aatctggcga tttttgggaa
     6601 ggttcaggaa ctccccggaa tggccggaga gcaaaactga agaatgccgc gatcaggatt
     6661 ttttccagaa tttccaccac ggagaatgat cctgtgaaga atgtccgtgc ttgtgctcca
     6721 gaagctgcat agcctggcga agggaatcga tatgttcatc gcgcgcttta acagcgcctt
     6781 taaggccatc gttttcagct tcaagcaaag caattctatg ctgtaagtca tgtaaaccct
     6841 ggttgttaac ctctgtagac ttagcgtcaa tatttacatc atattttaca ctgtcgatta
     6901 caccatcaag agaaccaaaa actctaataa gctctgatgt atcaataact ttaatatcct
     6961 taccttgctt tacaacagag gtgtaactta gcttcccact gttaagcatc ttgtaaattg
     7021 tggggcgact aaccttaaca agccgtgcag cttcactaat agacactctg gccatcagtt
     7081 accatcctgt aatgcatcca gtctcgagga cagtgtacgg aaaagatgct cggcatcatc
     7141 atggagtttc tcacaaaggt cagcctcagc atcgagatca agctcgttaa gcttccccag
     7201 caggagcagg gactgattct ggataaattt agccatgttc agcgcggtcg tctgttgttt
     7261 tgtcataaag gcctcagagc gtcagtactc gatgttaaac cggtctcttt tccgcttcct
     7321 cgctcactca gtcgctacgc tcctgccgtt cggctgcggc gagcggtgac aactcacgta
     7381 taagggcata agacgacagc acagatagcc agagcgaaca aaagaaagcc acggagttgc
     7441 cgtttttcca taggctccgc ccccctgaca agcatcacga aatatgacgc tcaaatcagc
     7501 ggtggcgaaa cccgacagga ctttaaagat accaggcgtt tccccctgat ggctccctcg
     7561 tgcgctctcc tgttcctgcc ttcggtttac cggtgtcatt ccgctgttat ggccgcgttt
     7621 atctcattcc acgccagaca ctcagttccg ggaaggcagt tcgctccaag ctggactgta
     7681 tgcacgaacc ccccgttcag tccgactgct gcgccttatc cggtaactat cgtcttgagt
     7741 ccaacccggt aagacatgca aaagcgccac tggcagcagc cattggtaac tgatttagag
     7801 gagttagtct tgaagttatg cgc
//
