LOCUS       NZ_CP145155            16906 bp    DNA     circular CON 05-APR-2024
DEFINITION  Citrobacter portucalensis strain CAVp365 plasmid pKPC_CAVP365,
            complete sequence.
ACCESSION   NZ_CP145155
VERSION     NZ_CP145155.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN22837217
            Assembly: GCF_036785855.1
KEYWORDS    RefSeq.
SOURCE      Citrobacter portucalensis
  ORGANISM  Citrobacter portucalensis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 16906)
  AUTHORS   Sheppard,A.E., Barry,K.E., Parikh,H.I., Vegesana,K., Sebra,R.,
            George,S., Sanderson,N.D., Stoesser,N., Eyre,D.W., Crook,D.W.,
            Walker,A.S. and Mathers,A.J.
  TITLE     Tn5403 promotes plasmid rearrangements and degradation of the
            Klebsiella pneumoniae carbapenemase (KPC) transposon Tn4401
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16906)
  AUTHORS   Sheppard,A.E., Barry,K.E., Parikh,H.I., Vegesana,K., Sebra,R.,
            George,S., Sanderson,N.D., Stoesser,N., Eyre,D.W., Crook,D.W.,
            Walker,A.S. and Mathers,A.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2024) Biological Sciences, University of Adelaide,
            Victoria Drive, Adelaide 5005, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye and Pilon v. 2.5 and 1.23
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 192x and 97x
            Sequencing Technology             :: Oxford Nanopore and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_036785855.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 15:44:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,724
            CDSs (total)                      :: 4,604
            Genes (coding)                    :: 4,540
            CDSs (with protein)               :: 4,540
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 26 of 64
            Pseudo Genes (incomplete)         :: 36 of 64
            Pseudo Genes (internal stop)      :: 12 of 64
            Pseudo Genes (multiple problems)  :: 10 of 64
            Pseudo Genes (short protein)      :: 1 of 64
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP145155.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..16906
                     /organism="Citrobacter portucalensis"
                     /mol_type="genomic DNA"
                     /strain="CAVp365"
                     /host="Homo sapiens"
                     /db_xref="taxon:1639133"
                     /plasmid="pKPC_CAVP365"
                     /geo_loc_name="USA:Virginia"
                     /lat_lon="38.14 N 78.45 W"
                     /collection_date="2016-12-01"
                     /collected_by="Clinical Microbiology University of Virginia
                     Health System"
     gene            join(16717..16906,1..134)
                     /locus_tag="LMH26_RS23545"
                     /old_locus_tag="LMH26_23545"
     CDS             join(16717..16906,1..134)
                     /locus_tag="LMH26_RS23545"
                     /old_locus_tag="LMH26_23545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_004193914.1"
                     /translation="MLTMWVTEDEHRRLLERCEGKQLAAWMRQTCLDEKPARAGKLPSI
                     SPALLRQLAGMGNNLNQIARQVNAGGGSGHDRVQIVAALMAIDAGLERLRHAVLEKGAD
                     DDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            343..>777
                     /locus_tag="LMH26_RS23550"
                     /old_locus_tag="LMH26_23550"
                     /pseudo=""
     CDS             343..>777
                     /locus_tag="LMH26_RS23550"
                     /old_locus_tag="LMH26_23550"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            812..1297
                     /locus_tag="LMH26_RS23555"
                     /old_locus_tag="LMH26_23555"
     CDS             812..1297
                     /locus_tag="LMH26_RS23555"
                     /old_locus_tag="LMH26_23555"
                     /inference="COORDINATES: protein motif:HMM:NF016710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_025367738.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQTTGEMLKAAFSEHEKSVRAELSESE
                     KRISAAILDHDRKLSSAMSQRTKGMLRMVSQTWLTIVLVSALLIASSAGILWWQGQQIL
                     ENYTTIREQKSTQAMLSERNSGVQLSTCGEQRRRCVRVNPEAGQFGEDSSWMILAGK"
                     /name="MbeB family mobilization protein"
     gene            1301..1516
                     /locus_tag="LMH26_RS23560"
                     /old_locus_tag="LMH26_23560"
     CDS             1301..1516
                     /locus_tag="LMH26_RS23560"
                     /old_locus_tag="LMH26_23560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_024195375.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWENAFAEWRTMSGLIQRENA
                     ALNERVTVLSRQVQSLSEQLRRLSKG"
                     /name="MbeD family mobilization/exclusion protein"
     gene            1684..>1896
                     /locus_tag="LMH26_RS23565"
                     /old_locus_tag="LMH26_23565"
                     /pseudo=""
     CDS             1684..>1896
                     /locus_tag="LMH26_RS23565"
                     /old_locus_tag="LMH26_23565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309641.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA];
                     GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family transporter"
                     /name="SMR family transporter"
     gene            complement(1950..3665)
                     /gene="tnpR"
                     /locus_tag="LMH26_RS23570"
                     /old_locus_tag="LMH26_23570"
     CDS             complement(1950..3665)
                     /gene="tnpR"
                     /locus_tag="LMH26_RS23570"
                     /old_locus_tag="LMH26_23570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="WP_004152391.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            3775..6807
                     /gene="tnpA"
                     /locus_tag="LMH26_RS23575"
                     /old_locus_tag="LMH26_23575"
     CDS             3775..6807
                     /gene="tnpA"
                     /locus_tag="LMH26_RS23575"
                     /old_locus_tag="LMH26_23575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="WP_338457576.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFESPKAITKHE
                     RYTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPG
                     YTTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFG
                     WRQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQ
                     LYLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLL
                     SLYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRM
                     RRHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPY
                     LLTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDV
                     LAKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKS
                     ENEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIA
                     QAMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLE
                     TLYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHH
                     VFDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDP
                     AQYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRA
                     IFEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIE
                     IEISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHY
                     TFQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     gene            6914..7939
                     /gene="istA"
                     /locus_tag="LMH26_RS23580"
                     /old_locus_tag="LMH26_23580"
     CDS             6914..7939
                     /gene="istA"
                     /locus_tag="LMH26_RS23580"
                     /old_locus_tag="LMH26_23580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_004199214.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            7936..8715
                     /gene="istB"
                     /locus_tag="LMH26_RS23585"
                     /old_locus_tag="LMH26_23585"
     CDS             7936..8715
                     /gene="istB"
                     /locus_tag="LMH26_RS23585"
                     /old_locus_tag="LMH26_23585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="WP_004152394.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            9102..9983
                     /locus_tag="LMH26_RS23590"
                     /old_locus_tag="LMH26_23590"
     CDS             9102..9983
                     /locus_tag="LMH26_RS23590"
                     /old_locus_tag="LMH26_23590"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /protein_id="WP_004152396.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKYSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-3"
     gene            complement(10233..>11198)
                     /locus_tag="LMH26_RS23595"
                     /old_locus_tag="LMH26_23595"
                     /pseudo=""
     CDS             complement(10233..>11198)
                     /locus_tag="LMH26_RS23595"
                     /old_locus_tag="LMH26_23595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(11232..14129)
                     /locus_tag="LMH26_RS23600"
                     /old_locus_tag="LMH26_23600"
     CDS             complement(11232..14129)
                     /locus_tag="LMH26_RS23600"
                     /old_locus_tag="LMH26_23600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            14224..14829
                     /locus_tag="LMH26_RS23605"
                     /old_locus_tag="LMH26_23605"
     CDS             14224..14829
                     /locus_tag="LMH26_RS23605"
                     /old_locus_tag="LMH26_23605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            complement(<14862..15221)
                     /locus_tag="LMH26_RS23610"
                     /old_locus_tag="LMH26_23610"
                     /pseudo=""
     CDS             complement(<14862..15221)
                     /locus_tag="LMH26_RS23610"
                     /old_locus_tag="LMH26_23610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            <15577..15699
                     /locus_tag="LMH26_RS23615"
                     /old_locus_tag="LMH26_23615"
                     /pseudo=""
     CDS             <15577..15699
                     /locus_tag="LMH26_RS23615"
                     /old_locus_tag="LMH26_23615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784643.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="QacE family quaternary ammonium compound efflux
                     SMR transporter"
                     /name="QacE family quaternary ammonium compound efflux SMR
                     transporter"
     gene            complement(15908..16078)
                     /locus_tag="LMH26_RS23620"
                     /old_locus_tag="LMH26_23620"
     CDS             complement(15908..16078)
                     /locus_tag="LMH26_RS23620"
                     /old_locus_tag="LMH26_23620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004193911.1"
                     /translation="MHEPPVQSDYHARSGNYQLESNPERHDKSPVAVAIGNWVHGAEIV
                     ENAYRVLEVKA"
                     /name="hypothetical protein"
     ARG             9103..9980
                     /name="blaKPC-3"
                     /gene="blaKPC-3"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1685..1974
                     /name="qacJ"
                     /gene="qacJ"
                     /gene_name="small multidrug resistance (SMR) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="disinfecting agents and antiseptics"
                     /identity="50.75"
                     /coverage="89.72"
     Typing          16430..16621
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="92.821"
                     /coverage="89.0"
                     /evalue="7.28e-73"
     Typing          complement(15967..16447)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="84.867"
                     /coverage="93.0"
                     /evalue="1.73e-132"
     Typing          125..1614
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.784"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16718..16905
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.825"
                     /coverage="99.0"
                     /evalue="1.61e-34"
ORIGIN
        1 cccgccaggt taacgccggt ggtggaagcg gacacgaccg cgtgcagatt gtcgccgcgc
       61 tgatggccat cgatgccgga ctcgagcggt tgcggcatgc cgtactggaa aagggtgctg
      121 atgatgatcg ttaagtttca tcctcggggg cgcggcggcg gcggcgggcc ggtcgattat
      181 ctgctgggta aagatcgcca gcgcgacggc gccagcgttc tgcaggggaa gccggatgaa
      241 gtccgggagc ttatcgacgc ctcgccctac gccaaaaagt acacttccgg cgttctgtct
      301 tttgccgaac aggatttacc gcccggccag cgcgaaaagc tgatggcgag tttcgagcgg
      361 gttctgatgc ccggactcga taaagaccag tacagcgtgc tgtgggttga gcaccgggac
      421 aaggggcggc tggagctgaa cttcctgatc ccgaacacgg agcttctgac cggcaagcgg
      481 ctacagccgt attacgaccg cgccgaccgt ccgcgcatcg atgcctggca gaccatagtg
      541 aacggcaggc tggggctgca tgacccgaac gcgccggaga accggcgggt gctggtctcg
      601 ccttccgcgc tgccggaagc gaagcaggaa gccgcccagg cgattacgag cggcctgctt
      661 gcccttgcct catccgggga gctgaaaacg cgtcaggacg tcactgaggc gctggaaagc
      721 gcaggttttg aggtggtgcg caccacaaaa agcagcatca gcattgccga cccggacggg
      781 gggcgaaaca tccgactgaa gggagccatc tatgaacagt cttttaacgc tggcgaagga
      841 cttagagcag aaatcgaaag cgcagcagca gactaccggc gagatgctga aagccgcatt
      901 cagcgagcac gagaagtctg tcagagcgga actgagcgaa agcgagaaga gaatcagcgc
      961 cgccatcctc gaccacgacc ggaagctgtc ctcagccatg agccagcgca cgaaagggat
     1021 gctgcgcatg gtcagccaga cgtggctgac catcgttctg gtctccgcgc tgctgatagc
     1081 gtcgagcgcg ggcattctgt ggtggcaggg gcagcagata ctcgagaact atacgaccat
     1141 ccgggagcag aagagcacgc aggccatgct gtcagagagg aacagcggcg tacagctctc
     1201 gacctgcggc gagcagagac gccgctgcgt gagggtgaac ccggaagcgg gacagttcgg
     1261 agaggactcg agctggatga tactggcggg gaaatagcac atgacggagc tggaaaaaca
     1321 gttgctgagc gcattagagc agctacagca ggactactcg aaaaggctgg acgagtggga
     1381 gaacgccttc gcggaatggc ggacgatgtc tggtcttatt caacgggaga acgcggcgct
     1441 gaacgagcgc gtcacggtct tgagcaggca ggtgcagagt ttgagcgagc agctgcgccg
     1501 gttgtcgaaa ggctgaacgc gatagaaact caccggcagc aggagcgggc ggtgcagcac
     1561 cagaaagcgc tggagctgga acgatcgcag tggcagcatc atggtccttc gctatgataa
     1621 gccgggttct attaattagt tgttatgtaa agatatttaa atttttcaac atgaggtatt
     1681 tttatgaata catatatttt cctgggaggg gctattgtgg ctgaagtcat aggcaccacc
     1741 tttatgaaat attcagaagg atttacacgc ctgtggccgt ctgtaggaac tgcaataagt
     1801 tattgcgctg ccttttatct gctttcccaa acattggaaa atatacctac cggtattgct
     1861 tacgcaattt ggtctggtgc gggaattgta ctaataaggg gttctaagcg ggaatcccag
     1921 aaaattccgt cattccgtat gatgaaaatt cagtcgactc ctcgcttgac gtgacgagcg
     1981 ccaaaagcct gccgcatctg cctggcgcgc tcgagctcat cgccatgcaa atacatcgac
     2041 gtcgtggcga tcgacgcatg gcgtaggttg tcgcgcaccg cggtgagctg agctccccgg
     2101 gccaacgcat ggctggcatg actgtgacgc atccaatgag gcgtggcacg gcgcagcttt
     2161 tcggcggcga ccggatgatc ggcctcaatg gcctcagcgg cttgcgtaaa gaatcttcgc
     2221 aacacgcacc aaaggtgagg gccggtgatg ccggcattac cgtcttcccc aagactgccc
     2281 accaggggcg ttttcggatt ccaccgttcc cggctgactg gcagttgacg ctgtgccaag
     2341 tattggtcca gcgccgtata cgcgagcggc ggcaaggcca ccttacctgg tttgccacct
     2401 ttgccaacca aatgcagcca gtggtcaccg tgctcgtcga ggcggacatt acccaggacg
     2461 gcgccgacca gttcgctagc gcgcaggccc gtggcatagc cgaagtcgag catgaagcgc
     2521 aggcgttgtg ctgccggctc ggaccagccg taggaccatt ccaggccgtc tgcaatggcg
     2581 cgcagcagta gccattctcc ctcggtaaag cctcgcgccg tatccagtgc gggccgcaag
     2641 gcgtgaccgc gtaccttgac gccggcgaaa gggttggcca gcacatagcg ctgctcgatg
     2701 agccaccgga acagcgccga gagcaccgtc agcgcatacg ctgccgagcg tgcggacaag
     2761 ccgcccgaga aggggcgcca ttccaccgaa tcgcgtggtc gaggtggccc cacccaacgc
     2821 tcgcgcgggg tcgggtgccg gacaaaggcc cggtacgcga ttgcatcgtc cgtggtcagg
     2881 gatgatagcg cccgtccgcg ttcgacgatg gcccacagga ttagccgcgc agcctccttg
     2941 cgataggcgc gctgtgtggc gacagtctcg tgcagcgcca gccaggcctg cacggcctcg
     3001 tagtcgttgg tcgcattcag cgtgcaagcg ttgcgcgggg cccggaaatt gccctgcgag
     3061 ccgtcgactt cgttcggcag acgcaactgc tcccacggca cgatgccgct gggctgaata
     3121 atcgggatca gggcccgggc gcgctcggtg agctgcggat gtgcggcaaa gaaagcctcg
     3181 acctgccggg cgcctgtcat gccgagtccc tcgatggctt tccaccagcc acgccggcgg
     3241 ggaatgcgca cggtcagcgc cgagagggtg tggataccgt acgcctgcag tgccctgacg
     3301 gtcctcggag acagccactg gtcgatgctg tcgctgatct ggggcttcgg cgccggcagc
     3361 gtgggcaaga gccggatcgc gcgttcgacg gcacccgcgc gcccctgtcg ctcttcgggg
     3421 gcgtgctgga acacgtcggc cagatccggc cggtggcggc tgttggcgaa aacgatgagc
     3481 tggcggcgga tatgccccag catccctcgc gctgattgac cggcggcctt gcgtgccgcc
     3541 aggtagtgtt caacggccgc gcgagagctg agtcccgcgt accagccgcg caaggcagcc
     3601 agcgaatccg catcgggaaa gccgactggg gtagaactcg aagccgtagt ctggcccgtt
     3661 ttcatatgga caggttgcga ttcgaaaagc gagtaacgcg ataataacga ttatttcagt
     3721 agaatcgaaa atgccccatg tttctacgaa acctcaagat agcaagaacg ggccatgagc
     3781 aagaagaaca agctactcag cgtcctatcc gacgccgaac aggaggcctt gtatggcctg
     3841 ccggagttcg atgatgcgca gcagctggaa tatctggctg tgacagaaac cgagttggcg
     3901 cttgccaaca gccggcccag tcttcatgcc aaggtctatt gcctcttgca gatcggctac
     3961 ttcaaggcca agcatgcctt cttcagtttc gactgggacg aagtcgagga cgattgcgct
     4021 ttcgtgctga gccgctattt ccacggcgag gtgttcgaaa gccccaaggc gatcaccaag
     4081 catgaacgct acacccagcg cgagcagatc gccaaactat tcggctactg gccgtggtcg
     4141 gccgccttcc tgccgcagct cgagcagcag gccgcacgga ccgtgcggcg tgacgtaacg
     4201 ccggggttcg tcgccgccga gctgatcgtc tggctcaatg agcacaagat tatccggccc
     4261 ggctatacga ccttgcaaga gttggtcagc gaaacgctat ccgccgagcg ccggcgcctg
     4321 ggcaatctgc tggagcaagc gttggacgaa tctgccaagg ccgcgctgag ccagcttctg
     4381 gtccgtgatg acaccctgtc gcaactggcg gcgctcaagc aggacgccaa gaatttcggc
     4441 tggcgccaga tggtccgcga gcgcgaaaag cgcgccacgc tggagccgct gcacgcaatc
     4501 gccaagacac tgctgcctaa actcgacgtc tcgcagcaga acctgctgta ctacgcgagc
     4561 ctggcaaact tctacaccgt ccacgacctg cgcaatctga aggccgatca gacccaactc
     4621 tacctgctgt gctatgcctg ggtacgctac cggcagctct ccgacaacct ggtcgatgcg
     4681 atggcgtacc acatgaagca gttggaggac gaaagcagcg ctggtgccaa acaatccttt
     4741 gccgacgagc aggtgcgccg tcagcaggaa acgccgcggg taggccgcct gctgtcactc
     4801 tacgttgatg atagcgtggc cgatcccacg cccttcggcg aggtgcggca gcgcgcctac
     4861 aagatcatgc ctcgcgatac gctgcaaacc acggcgcagc gtatgagcgt gaagccggcg
     4921 agcaagctgg ccttgcagtg gcaggcggtg gacgggctgg ccgaccgcat gcgccgccat
     4981 cttcgtccac tgtacgttgc gctcgacctc tccggctcca atccagacag tccatggctt
     5041 gccgcgctgg cctgggccaa aggtgttttt gccaagcagc agcggctgtc gcaacggcca
     5101 ctcgacgagt ggcccgcggc gacacttccg aaacgcttgc ggccgtacct gctgaccttc
     5161 gacgccgacg gtaaaccaac cggcctgcac gctgaccgct acgagttctg gctgtaccgc
     5221 cagatcagga agcgtctcca atcgggtgaa ctctacctcg acgacagcct gcaacaccgg
     5281 cacttctcag atgaactggt tgagatggac aggaagatcg atgtgctcgc aaaaatggag
     5341 atccccttcc tgcagcaacc cgtccatgcc caactcgatg cgctgactgc cgaactgcgc
     5401 acgcagtggc tggcgttcaa ccgcgagctg aaacagggca agctgacgca cctcgaatac
     5461 aacaaggaca cgcagaaact gacctggcgc aagcccaaga gcgagaatga gaaagcgcgc
     5521 gaaaaggcat tctacgagaa gcttccgttc tgcgacgtgg ccgacgtgtt tcgcttcgtc
     5581 aacgacgagt gcaagtttct gtcggcgttc acgcccatgc agccgcgcta cgcgaagaag
     5641 gtcgccgacg ctgacagcct gatggcggtc atcatcgcgc aagcgatgaa ccacggcaac
     5701 cacgtcatgg cgcgcaccag cgacatcccg taccacgtgc tggatagcgg ctaccagcag
     5761 tacctgcgcc aggcaacgct gcacgcggcc aacgactgca tcagcaacgc catcgccacg
     5821 ctaccgatct tcccatacta ctcgttcgac ctcgaaacgc tgtacggtgc cgtcgacggg
     5881 cagaaattca gcgtcgaacg gccgaccgtg aaggcgcgct attcgcgcaa gtacttcggg
     5941 cgcggcaagg gcgtggtcgc ctacacgctg ctgtgcaacc acatcccgct caacggctac
     6001 ctgatcggcg cgcacgacta cgaggcccac cacgtgttcg acatctggta tcgcaacacg
     6061 tcggacatca tgccgaccgc gatcaccggc gacatgcaca gcgtcaacaa ggccaacttc
     6121 gccatcctgc attggtttgg ccggcggttc gagccgcgct tcaccgacct caacgcgcaa
     6181 ttgaaagaac tctactgcgc tgacgatcca gcacagtatc aggcgtgcct gattcggcca
     6241 gtcgggaaaa tcgactgcga tctcatccat cgcgagaagc cgaacatcga ccggatcgtc
     6301 gccacactcg ggctgaagga aatgacgcag ggcacgctga tccgcaagct gtgcacctac
     6361 accacgacga acccgacgcg gcgcgcgatc ttcgagttcg acaagctcat ccgcagcatc
     6421 tacacgcttc gctacctgcg cgatccgcaa ctggaacgca acgtgcaccg ctcgcaaaat
     6481 cgcctcgagt cctaccatca gctacgctcg gccattgccc aggtcggcgg taagaaggaa
     6541 ctgaccggtc gcaccgacat tgaaatcgag atcagcaacc agtgcgcacg gctgatcgcc
     6601 aacacgatca ttttctacaa ctcggcaatc ttgtcgcggc tggtgaccaa gtacgaggcg
     6661 gccggcaaca gcaaggcgct ggcactcatc acaaaaattt cgcctgcggc atggcggcac
     6721 atcctgctca acgggcacta cacctttcaa agcagcggca agacgatcga tctcgatgcg
     6781 atcgtcgcag gcctggaact ggagtgacgg aattttcagc ggttccgtgt tagcagcagt
     6841 gtaaaactga cccaccccag cgaagtaaaa ctgatccacc tgggctagtt tggcggcctt
     6901 ttcgaggccg tcgatgttga cccaggagca aaccgtggaa atcagagttc ttgcccgaca
     6961 gggccactcc atccggcaca tcgcccgcac gttgggggtc tcgcgcaata ccgtgcgccg
     7021 ctacctccgc gatccgtcgg tagcgcgata ccagccccgt gaaccacgcc ccaccaaact
     7081 ggggccattt gaatcttatc tgcggcaacg ggtcgagcag gcccacccca tctggctgcc
     7141 tgccaccgtc ctgaatcggg aaatccgcgc tcaagggtat ggcggcggtc tctcgttatt
     7201 gcgcgccttc ctcgccacgc tcaagcccgc ccgccgcgaa gcaggtccgg ccgtccgttt
     7261 cgagaccgag cccggacggc agttgcaggc tgatttcgtg gtcttgcgcc gggccagatc
     7321 ccccatgtcg gccttcgtcg ccacgctggg atacagccgc atgacgtttg tcaccttcgt
     7381 accggacgaa tccttcgagt ccgtgcggga ctccctgttg ctggcttttg actatctggg
     7441 cggtgtgccc cgcgaggtgt tgttcgacaa catgaagacc gtggtgctgg aacgcgatgc
     7501 ctacggtgac ggcaagcacc gttttcaccc cggcttgctt caactggccg atgacctggg
     7561 gttccggatc cggctgtgtc gcccgtatcg ggcccagacc aaaggcaagg tcgagcgctt
     7621 caatcgctac ttccgcgaga gcttctacaa cccgttgctg acccggatga agggcacggg
     7681 gctgctgctc gattgtgctg ctgccaaccg acgcgtccgt gactggttgg cagacgaggc
     7741 gaatgtgcgg gtccacgcca ccctgaacga gcgccccatc gaccgttggc ggcaggagcg
     7801 ggaacacctg caacccttgc catcccgtgt gcggcgcgac gaggcccccc tgctggataa
     7861 cagtctccgc ccggtaccac tggaatctct ccagcaccca ctgtctgtct atgacgcaat
     7921 tggggaggcc tgccgatgaa cctccagcat gagcggatcg acgccctgtg ccagcaactc
     7981 aaactcgaac gggtggcaac gcattacccc gtcctggcgc agcaggcggt gcgcgaggac
     8041 ttcagcttca ccgacttcct ggaacacctg ttgcggcatg aagcggggtg tcgccagcag
     8101 cgcagccgcg aactgctgac gcggatggct tgcttcccgg gcatcaagac cctggaggac
     8161 tatgacttca gcttcaaccc cggcgtgccc aaggcactgg tgcaggagct gggcagtctg
     8221 gcgtttgtcg aacgggccga gaacgtggtg ctgatcggac cctctggcat cggcaagacc
     8281 cacctcgcca tcgccttggg ttacaaggcc gcgcaagccg gggtcaagac acgcttcatc
     8341 acggcagccg acctgatgct gcaactgagc acggcgcagc gacaagggcg gctgaaggaa
     8401 tacttcaacc gcgccatcct cggtccacgg ctgctggtga tcgatgagat cggctacctg
     8461 cctttcggac gcgaggaagc gaacctgttc tttcaggtgg tggcgaagcg ctatgagaaa
     8521 ggggcgatga tcctgacctc gaacctgccg ttcagccagt gggccgacgc gtttgccggc
     8581 gataccaccc tgacagccgc gatgctggat cggctgctgc accatgccca tatcctgacc
     8641 ctgagcggcg aaagctaccg cttgaaggac aagaggaagg cgggagtggt caggaaaaat
     8701 tccaaacccg aatgatccag gtgggtcagt attactttgg tgattcaggg gtaaagtggg
     8761 tcagttttca gttggtgttg acaccggcgt accctcggtg ctatcttcgc gccccaatag
     8821 tcggggcttg gccaggactt cctgaggccg tccgtaacgt ggatgccgag gtcaggcgag
     8881 gtggccgacc catgaacgcc gacctgattc gtttttcaat agcgctggac gttgtggtgc
     8941 cagggactta ccaacccgat gtgtgcccat ccggggcagt tacagccgtt acagcctctg
     9001 gagagggagc ggcttgccgc tcggtgataa tcccagctgt agcggcctga ttacatccgg
     9061 ccgctacacc tagctccacc ttcaaacaag gaatatcgtt gatgtcactg tatcgccgtc
     9121 tagttctgct gtcttgtctc tcatggccgc tggctggctt ttctgccacc gcgctgacca
     9181 acctcgtcgc ggaaccattc gctaaactcg aacaggactt tggcggctcc atcggtgtgt
     9241 acgcgatgga taccggctca ggcgcaactg taagttaccg cgctgaggag cgcttcccac
     9301 tgtgcagctc attcaagggc tttcttgctg ccgctgtgct ggctcgcagc cagcagcagg
     9361 ccggcttgct ggacacaccc atccgttacg gcaaaaatgc gctggttccg tggtcaccca
     9421 tctcggaaaa atatctgaca acaggcatga cggtggcgga gctgtccgcg gccgccgtgc
     9481 aatacagtga taacgccgcc gccaatttgt tgctgaagga gttgggcggc ccggccgggc
     9541 tgacggcctt catgcgctct atcggcgata ccacgttccg tctggaccgc tgggagctgg
     9601 agctgaactc cgccatccca ggcgatgcgc gcgatacctc atcgccgcgc gccgtgacgg
     9661 aaagcttaca aaaactgaca ctgggctctg cactggctgc gccgcagcgg cagcagtttg
     9721 ttgattggct aaagggaaac acgaccggca accaccgcat ccgcgcggcg gtgccggcag
     9781 actgggcagt cggagacaaa accggaacct gcggagtgta tggcacggca aatgactatg
     9841 ccgtcgtctg gcccactggg cgcgcaccta ttgtgttggc cgtctacacc cgggcgccta
     9901 acaaggatga caagtacagc gaggccgtca tcgccgctgc ggctagactc gcgctcgagg
     9961 gattgggcgt caacgggcag taaggctctg aaaatcatct attggcccac caccgccgcc
    10021 cttgcgggcg gcatggatta ccaaccactg tcacatttag gctaggagtc tgcgcggcag
    10081 agccgtgtga ccggttttct gtagagcact gacgatggcg gcggcgctct ctgcaattgg
    10141 caaggcgtcg gcgccaagga taccaatctt gcggcgcgcg gcgtgttatg acgactgggg
    10201 tgcatttgag ccgccccatt taaccttcgc cctcacagat acgccattcg cctcagattt
    10261 agcgccatgc agacgagctt ccactcggct tgcaccttgt ccaggcccct catgctgaac
    10321 tgacgcaatc ccatcaccgc cttgatccaa ccattcggag cctccacgat cgacttgcgc
    10381 cggcggtaag ctgcatcgcc ttgctccgtt ttcaatttcg ccgcaatcgc cgccgtatgc
    10441 ggatgggtct tggcattgac cttggcatct tcacgtccct cgcggccgag ggcaacgatg
    10501 acatcgccgt ggtgatcggc gacctttgcc agaacagcct cactacggaa tcccgcatcc
    10561 gccagcgtct gggccggcat ttctccggtg ttggcctgaa ctgctgccag catgcccagc
    10621 agcgcctgac tgtccgcggc gcagttggtc aactccgccg ccacgatgat ctggtgctcg
    10681 gcatcgaccg ctgtgtaccc gttgtagctc tgctcggagc caccaccggc gtgtttcatg
    10741 atccggctgt ccggatcggt gaagctttcc tgatcacggt catccggcac accaaactcg
    10801 cgtttgtacg agccaccgcc cttgtccgag ccatccggat ggcgaggccg gcggccatcg
    10861 tcttcgctgc gcccccgggc ctggtccgct tcacgctggc gcgcttccag gcgcgccttt
    10921 gccgcctgga tcgcctccag gcgcttctcg cggcgagaaa tctcggcagg aatgtccagc
    10981 tccggctcgt tacgctcctg gtcgtcggta gccttggcgc gatcaagcag cgccttgatc
    11041 tcgcaatgca attcgtcctc ggccggcttc atgcgcttat agctcatcgc cttgtggcgg
    11101 ctggcgttgg cttttacctt ggtgccgtcg accgcgatcg tgccaagctt caccagccca
    11161 cattcgcgcg ccagttgcac cacctgaacg aacaaattgg ggtcggttcc ggctgagggc
    11221 gaaatgacac cctaagcttt cggttccttg ggccaaagat attcgccagt cagtagaatg
    11281 tgcgcccagc ccaatgggga tatgtgggga agaaattcag ggggaacatc caacccttcg
    11341 ttccgccgct ccgtgacggc atgaccaaga tggacggtat tccagtaaat gatcaccgca
    11401 gtcaataaat tgagcccagc gattcggtag tgctgcccct ctgtcgtgcg atcgcgaatt
    11461 tccccctgcc tcccgatacg gagcgcattt ttgagcgcat ggtgggcctc tcccttgtta
    11521 agaccgatct gagcacgccg ctgcatgtcc gtatccagga tccactcaat aatgaaaagg
    11581 gtccgttcaa tacgaccaac ttcacgaagc gcaactgcaa ggttgttttg tcgtgggtaa
    11641 gaagcgagct tgcgcaggag ttggctgggc ctgattttgc cagcggtcat cgtcgcggca
    11701 caacggaaaa tatcaggcca gttcgcaacg ataagatcct cccgggcttt tccacctacc
    11761 aacttgcgta actccctggg ggtcgtatcg ggattaaata cgtacaaccg cttcgatggc
    11821 agatccctga ttcgcagaac gagattgtag ccgagcaggc tactggctcc gaacaaatgg
    11881 tcggtgaatc ctgctgtatc ggcatactgt tcgcgaacat ggcgaccgac ctcgttcatc
    11941 agtagtccat cgagaatata cggtgcctcg ctcacggtcg ccgggatcga ctgacaagcg
    12001 aatggcgcga actggtcgct tacgtgagta tacgctttga ggccgggaac agaaccatat
    12061 ttggcattga ccatgttcat ggcttcgcca tgccgcgctg tcgggaaaaa ctgaccatcg
    12121 ctcgatgctg acgtgcccat cccccagacg cgtgacatcg gcagtttacc ctgcgcggcc
    12181 accacaattg ccaatgcctg gttcatggct tcgctttcaa catgccagcg ggcaaggcgt
    12241 gagagctgcc agtaatcatg cgtgtttgta gcttccgcca tcttacgcag gcccagattg
    12301 agcccttcag cgagcaggac gttgagcaga ccgatccggt cgcgacatgg agccccggtt
    12361 ctcagatggg taaacgcatc tgtgaaacca agggctgcat caacttcaag cagcatgtcg
    12421 gtaatccgaa cggacggcat tcggcgatac agatccagta tgagtgcctc ggcaccatcc
    12481 ggcacgtctg ctgtcaacct gtcgatccgc aacgttccat cttctatgct accgtgcgga
    12541 atagtgccgt tacgggcagc ccgggccagc cgcttaagag cgatcgtgag tcgcgccttt
    12601 ctgtctgcca gccaatcctg tgggttggaa ggcacggcca gttttgcatt ttcctgcgcc
    12661 gcgatcatcg gcaccagtac ctgcttgagg tcaccatagc ggcgcgaatg agcgagccag
    12721 acatctccgg aacgaaaagc atcccggagg tgaaagagta cagccacttc ccaaagacgg
    12781 gtatctcctt tttcctgagc tcgtaaatga cggttccatt tggagctggg ccgcaggaaa
    12841 cgcctttctg gcgatgcaac acctttcatc tctccgatcg acaaagctgc tgctaccaat
    12901 ggtccggcga ccggcgcggc ttcgagcttc agacagcgca acatgcgggg cgcataacga
    12961 cgaaagcgat ggtatccctg cccgacatat gcaagaggct catcggctag cgtgttgctg
    13021 agttgagtcc ctgtcgctac cagttgagcg agccggtccc atgcaaccga actggcgaca
    13081 gccatctcca gcggggttcc gtcactgcgg gcctcaagca acgaagctcc cagcgcggtg
    13141 aaggtacgga tcgtatccgt gagtgtggct ttagagccgg aaattgtttc gtcatgctgg
    13201 cgcttcgctt cccgccaggt ttttcctacg atcctgtcat gggtttcgac tatggcatca
    13261 gcaatcgccg cttcccactc cacaacacag acggcaagga tcgcccagcg gcggtccgaa
    13321 gtgatgtcac gcaaaccgtc ggtgaagtag cgttcaccct gccgacgcag ccgggcaatg
    13381 cgatgggcag gtatgctggc caaagcacta tgattgatat tcagggtacg cagaaattcg
    13441 agcctgtcga gcaaacggtt agcagcagcc gagttgttac caacctcgaa gttgcgaagc
    13501 cagatgaaac gactgatatt gccggcgagc atttcactca gaagtttgtc caggtgatcg
    13561 cgaacatccg ctgttaaatt ttccgcaatc cgcgtttcaa tccgccgctc agcggcgacc
    13621 agagcatccg cgcacaagcg ctcgattgtc gatactgcgg gcagaatggt ggaagtttcc
    13681 cgacaccgca caataaaacg atgagcaaga tcctcgtttg atctggcatc ttcggcctgg
    13741 ccgaaagtcc actcccgcag atcacgggca ccacggcccg tgaaggtctt gtagccgtaa
    13801 atttcgcgca gcgtgtccat gtgctgctga cgggtttggc gccgtgtggc ataagtgaga
    13861 agcgcatcag ccggaactcc aagctgagca ccgacgaagg aaaggacttc acgcgggatc
    13921 atctcaccag gagccagtgc acggcccgga tatcgtaagg cacaaagttg cagggcaaag
    13981 ccaatcctgt tttccggtct gcggcgctgc ctaatgtttt ccaggtcatc atcgcccagc
    14041 gtgtagaact tcagtagcga cagttcgtcc gtgggcagat cgaacagcgc tgctcgctgc
    14101 cgttcggtga aaatatggcg tcgtgacata caaattcgtc ccttttgaag tatagtctgt
    14161 tttggacaac agccagccca tataaatcag ggcgttccga tacaaaaatc caggagggtt
    14221 caattgggac atcgtgccgc catttactgc cgggtttcaa cagcggatca gtcttgtgaa
    14281 cgccaggaat ttgatctgcg agccttcgcc ggccgtgccg gctacgacgt ggtgggaata
    14341 tttaaggaaa caggttcagg aactaaactc gaccgggccg agcgaaagaa agtcctggcg
    14401 cttgcccagt ccagacaaat tgatgcaatc ctggtcactg agctttcccg gtgggggcgc
    14461 tcgacgctcg atctgctcaa tacgctacgt gaactggaga actggaaggt ttccgtgata
    14521 gccatgaatg gaatggcgtt cgatctttcg tcgccgtatg gacgaatgct ggcgacgttt
    14581 ctttccggca ttgcggagtt tgagcgggat ctcatcagcg agcgggtcaa gtcaggcctt
    14641 gctgttgcga aggcacgtgg taagaggctt ggtcgtcagg ccggagtgcg accaaaatca
    14701 gaccgacttt tgcctaaggt ggttgcgatg agggccgagg gacgcagcta tcgctggatc
    14761 gcacgcgagc tcggtatcag caagaatacc gtcgctgaca tcgtgcaacg acacagagct
    14821 aacgcttagg gtgtcatttc gccctcagcc ggaaccgacc ccaaattctc aagctcggtc
    14881 aggtgtaggg cacggaagtc actcagcgtg cggtgggccg ggaagtttcc agcggccagc
    14941 acacgcaacg cgacatcctc gtacagcttc ctggctagtt tgcgcgaaga gaagacgccg
    15001 ctcgcgtaac catagatcag cactttgacc atcatcgccg gatgaaacgg ctgattgccc
    15061 ggaccaccgc cggcataccg ggcgtggaat gcgctcaagt ccagcgtatc gacagtctcg
    15121 ctgatgaagt aggcaagatg cccttcaggt agccactctc ccagagaagg gggcagcaga
    15181 taggattggt cgggtcggta aggaaggtaa ctggcagcca tccccgtatc gtcctcgatc
    15241 ttccgccgat ttggcttctg ccgcgcaggc tcctaggcca ccgtagctaa acatacgaga
    15301 aaaaccgctt cttgagcgct ctctgagacc accttgccga caacgcagaa acggttgcgg
    15361 aaaaatcggc gtttccggcg tacgccaccc gacctggacg aactattgcg gacctggaac
    15421 tggagtagcg gaattccccg gggtttcagc gtcgcgccac agcgcctcag atagatgcgg
    15481 tagcctttgg cgggtcgtca tgccgcggac caccccccca aaaaattcca caatgcggaa
    15541 tggcggaatt ttctggggtt cccgcttacc cccccaataa gcctagctgg ttggttggtt
    15601 agcggtcaaa aacttgattg gcccgcaatt gcaggaatgt tccttatttg cgttggagtt
    15661 ttggttatta atattttttc aaaatcttct gcgcattaac tttttaccga agcatattgg
    15721 ccaaagcaaa aggatttcct tgagatcctt tctttctgcg cgtaatcttt ttccctgtaa
    15781 acaaaaaaac caccgctacc aacggtggtt cgtttgccgg aattcagagc taccaactct
    15841 ttgttccgat ggtaactggc tttcacggag cgcagatacc taaactgtcc tttcagtgta
    15901 gccgcactca ggctttcact tcaagaactc tgtaggcatt ctctacaatc tctgctccgt
    15961 gaacccagtt accaatggct accgccactg gcgatttgtc gtgtctttcc gggttggact
    16021 caagttgata gttaccggaa cgggcgtggt agtcggactg aacggggggt tcgtgcatac
    16081 agtccatcct ggagcgaact gcctacccgg aaccgagttt caggcgtgga atgagaaacc
    16141 gcggccataa cagcggaatg acaccggtaa accgaaaggc aggaatgcgg gggagcacga
    16201 gggagccacc agggggaaac gcctggtatc tttaagccgc atcgggtttc gccaccgctg
    16261 atttgagcgt cattttcgtg atactcgtca ggggggcgga gcctatggaa aaacggcaac
    16321 tccgcatcct tttcttggcc tttcctgctt cgagcggcat ttgcttatcc cgtaatctgt
    16381 gagctggtaa cgcccgccgc agtctcacgg caggagcgta gcgaccgagt gagcgaggag
    16441 gcgtcatttc atcaccacct gcattttgca cttacgcccg gcagccgcat ttttcccctg
    16501 tcacatgaag cactttcata aattaccact ccgtcataac atgtttagcc agtatacact
    16561 ccgctagcgc tacgtgactg gttcagggct gcgccccgaa acccgctaaa accactgccg
    16621 cgtctgcggc ttgtccaaca ccgtgccgac cgggaaaaga tttcccgtcc gtcccggcgt
    16681 tatcaggagg ccggattggc agacaaacgc agcaaaatgc tcaccatgtg ggtgactgag
    16741 gacgagcacc ggcgtctgct ggagcgctgc gagggtaagc aactcgcggc ctggatgcgg
    16801 cagacgtgcc tggacgagaa gcccgcacgc gccggcaaac ttccgtcgat ctcgccggcg
    16861 ctgcttcgtc agcttgccgg catggggaac aaccttaacc agattg
//
