LOCUS       NZ_CP140478            10688 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Klebsiella pneumoniae subsp. pneumoniae strain FF29-001BS plasmid
            Col440, complete sequence.
ACCESSION   NZ_CP140478
VERSION     NZ_CP140478.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38451788
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 10688)
  AUTHORS   Manyahi,J.
  TITLE     bla NDM5 Klebsiella pneumoniae Tanzania
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10688)
  AUTHORS   Manyahi,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-NOV-2023) Clinical Science, University of Bergen,
            Haukelands veien 208, Bergen 5020, Norway
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method              :: SPAdes v. May-2022
            Genome Representation        :: Full
            Expected Final Version       :: Yes
            Genome Coverage              :: 12.0x
            Sequencing Technology        :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI RefSeq
            Annotation Date              :: 01/08/2024 10:29:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision :: 6.6
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 18
            CDSs (total)                 :: 18
            Genes (coding)               :: 18
            CDSs (with protein)          :: 18
            Genes (RNA)                  :: 0
            tRNAs                        :: 0
            ncRNAs                       :: 0
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP140478.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10688
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="FF29-001BS"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /plasmid="Col440"
                     /geo_loc_name="Tanzania: Dar es Salaam"
                     /lat_lon="6.8165 S 39.2894 E"
                     /collection_date="2022-03-03"
                     /collected_by="Joel Manyahi"
                     /genotype="ST437"
     gene            13..237
                     /locus_tag="SNM26_RS00005"
                     /old_locus_tag="SNM26_28630"
     CDS             13..237
                     /locus_tag="SNM26_RS00005"
                     /old_locus_tag="SNM26_28630"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071653266.1"
                     /translation="MSNKDSLERKVTPRKNEPVFPMALRVGIAEDICFLELVDFPEKES
                     GRVFYSIALTKKHAKNLIDGLNKFVESGD"
                     /name="hypothetical protein"
     gene            239..883
                     /locus_tag="SNM26_RS00010"
                     /old_locus_tag="SNM26_28635"
     CDS             239..883
                     /locus_tag="SNM26_RS00010"
                     /old_locus_tag="SNM26_28635"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044816498.1"
                     /translation="MKYINHCDSEDYYITNDSIDLGVRYDVSDYNKLELNDLRDPDLFK
                     VLGRAFVVVENSVWESWNDDVKTLDCSGDGYESILKHYESLELSGEFLLFFKKIRSAIS
                     VYNREYEFCTGDLEPSLQAIVQLIRYAPELAAKKDAQIYFDKKSECFGLIYKQTKKSKG
                     TLNLIVKTNNEIIFSFVRKVSGVVKVTGRAYIGDSLDNSIAIKSLFKMMEW"
                     /name="hypothetical protein"
     gene            883..1359
                     /locus_tag="SNM26_RS00015"
                     /old_locus_tag="SNM26_28640"
     CDS             883..1359
                     /locus_tag="SNM26_RS00015"
                     /old_locus_tag="SNM26_28640"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_077861907.1"
                     /translation="MTVLSTLNNLKSIPCINAFTGRANNSYLWRYVMEDHKDEFGATTI
                     KCFYLREEISEDYVSIYHSNKDYYEGMVRDVHKRIPVGKTKPAIYLSFDAAEVIEQVNK
                     PDKCIDIKDEGYPHLGLWYLFDINDEFTLIEVTTTILELSSFFQRNEGGVVVPL"
                     /name="hypothetical protein"
     gene            complement(1566..1679)
                     /locus_tag="SNM26_RS00020"
                     /old_locus_tag="SNM26_28645"
     CDS             complement(1566..1679)
                     /locus_tag="SNM26_RS00020"
                     /old_locus_tag="SNM26_28645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071653267.1"
                     /translation="MHEPPVQSDCCAFSGNYQLESNPERHDEAPLAAATGN"
                     /name="replication initiation protein"
     gene            2095..2286
                     /locus_tag="SNM26_RS00025"
                     /old_locus_tag="SNM26_28650"
     CDS             2095..2286
                     /locus_tag="SNM26_RS00025"
                     /old_locus_tag="SNM26_28650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_044816495.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSGLDELQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            2286..2708
                     /locus_tag="SNM26_RS00030"
                     /old_locus_tag="SNM26_28655"
     CDS             2286..2708
                     /locus_tag="SNM26_RS00030"
                     /old_locus_tag="SNM26_28655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_044816494.1"
                     /translation="MARVSISEAARLVKVSRPTIYKMINSGKLSYTSVVKHGKNTKVVD
                     TSELIRVFGSLYGGGDTVKHDVKGDAGATGVNISGLHDLQHKIALLEAENDGLKGAVKA
                     RDEHIDSLRQAMQLLEHKLEPSPQVHSPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            3572..3796
                     /locus_tag="SNM26_RS00035"
                     /old_locus_tag="SNM26_28660"
     CDS             3572..3796
                     /locus_tag="SNM26_RS00035"
                     /old_locus_tag="SNM26_28660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071653266.1"
                     /translation="MSNKDSLERKVTPRKNEPVFPMALRVGIAEDICFLELVDFPEKES
                     GRVFYSIALTKKHAKNLIDGLNKFVESGD"
                     /name="hypothetical protein"
     gene            3798..4442
                     /locus_tag="SNM26_RS00040"
                     /old_locus_tag="SNM26_28665"
     CDS             3798..4442
                     /locus_tag="SNM26_RS00040"
                     /old_locus_tag="SNM26_28665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044816498.1"
                     /translation="MKYINHCDSEDYYITNDSIDLGVRYDVSDYNKLELNDLRDPDLFK
                     VLGRAFVVVENSVWESWNDDVKTLDCSGDGYESILKHYESLELSGEFLLFFKKIRSAIS
                     VYNREYEFCTGDLEPSLQAIVQLIRYAPELAAKKDAQIYFDKKSECFGLIYKQTKKSKG
                     TLNLIVKTNNEIIFSFVRKVSGVVKVTGRAYIGDSLDNSIAIKSLFKMMEW"
                     /name="hypothetical protein"
     gene            4442..4918
                     /locus_tag="SNM26_RS00045"
                     /old_locus_tag="SNM26_28670"
     CDS             4442..4918
                     /locus_tag="SNM26_RS00045"
                     /old_locus_tag="SNM26_28670"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_077861907.1"
                     /translation="MTVLSTLNNLKSIPCINAFTGRANNSYLWRYVMEDHKDEFGATTI
                     KCFYLREEISEDYVSIYHSNKDYYEGMVRDVHKRIPVGKTKPAIYLSFDAAEVIEQVNK
                     PDKCIDIKDEGYPHLGLWYLFDINDEFTLIEVTTTILELSSFFQRNEGGVVVPL"
                     /name="hypothetical protein"
     gene            complement(5125..5238)
                     /locus_tag="SNM26_RS00050"
                     /old_locus_tag="SNM26_28675"
     CDS             complement(5125..5238)
                     /locus_tag="SNM26_RS00050"
                     /old_locus_tag="SNM26_28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071653267.1"
                     /translation="MHEPPVQSDCCAFSGNYQLESNPERHDEAPLAAATGN"
                     /name="replication initiation protein"
     gene            5654..5845
                     /locus_tag="SNM26_RS00055"
                     /old_locus_tag="SNM26_28680"
     CDS             5654..5845
                     /locus_tag="SNM26_RS00055"
                     /old_locus_tag="SNM26_28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_044816495.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSGLDELQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            5845..6267
                     /locus_tag="SNM26_RS00060"
                     /old_locus_tag="SNM26_28685"
     CDS             5845..6267
                     /locus_tag="SNM26_RS00060"
                     /old_locus_tag="SNM26_28685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_044816494.1"
                     /translation="MARVSISEAARLVKVSRPTIYKMINSGKLSYTSVVKHGKNTKVVD
                     TSELIRVFGSLYGGGDTVKHDVKGDAGATGVNISGLHDLQHKIALLEAENDGLKGAVKA
                     RDEHIDSLRQAMQLLEHKLEPSPQVHSPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            7131..7355
                     /locus_tag="SNM26_RS00065"
                     /old_locus_tag="SNM26_28690"
     CDS             7131..7355
                     /locus_tag="SNM26_RS00065"
                     /old_locus_tag="SNM26_28690"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071653266.1"
                     /translation="MSNKDSLERKVTPRKNEPVFPMALRVGIAEDICFLELVDFPEKES
                     GRVFYSIALTKKHAKNLIDGLNKFVESGD"
                     /name="hypothetical protein"
     gene            7357..8001
                     /locus_tag="SNM26_RS00070"
                     /old_locus_tag="SNM26_28695"
     CDS             7357..8001
                     /locus_tag="SNM26_RS00070"
                     /old_locus_tag="SNM26_28695"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044816498.1"
                     /translation="MKYINHCDSEDYYITNDSIDLGVRYDVSDYNKLELNDLRDPDLFK
                     VLGRAFVVVENSVWESWNDDVKTLDCSGDGYESILKHYESLELSGEFLLFFKKIRSAIS
                     VYNREYEFCTGDLEPSLQAIVQLIRYAPELAAKKDAQIYFDKKSECFGLIYKQTKKSKG
                     TLNLIVKTNNEIIFSFVRKVSGVVKVTGRAYIGDSLDNSIAIKSLFKMMEW"
                     /name="hypothetical protein"
     gene            8001..8477
                     /locus_tag="SNM26_RS00075"
                     /old_locus_tag="SNM26_28700"
     CDS             8001..8477
                     /locus_tag="SNM26_RS00075"
                     /old_locus_tag="SNM26_28700"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_077861907.1"
                     /translation="MTVLSTLNNLKSIPCINAFTGRANNSYLWRYVMEDHKDEFGATTI
                     KCFYLREEISEDYVSIYHSNKDYYEGMVRDVHKRIPVGKTKPAIYLSFDAAEVIEQVNK
                     PDKCIDIKDEGYPHLGLWYLFDINDEFTLIEVTTTILELSSFFQRNEGGVVVPL"
                     /name="hypothetical protein"
     gene            complement(8684..8797)
                     /locus_tag="SNM26_RS00080"
                     /old_locus_tag="SNM26_28705"
     CDS             complement(8684..8797)
                     /locus_tag="SNM26_RS00080"
                     /old_locus_tag="SNM26_28705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045907702.1"
                     /translation="MHEPPVQSDCCALSGNYQLESNPERHDKAPLAAATGN"
                     /name="hypothetical protein"
     gene            9213..9404
                     /locus_tag="SNM26_RS00085"
                     /old_locus_tag="SNM26_28710"
     CDS             9213..9404
                     /locus_tag="SNM26_RS00085"
                     /old_locus_tag="SNM26_28710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_055314556.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSLRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            9533..9886
                     /locus_tag="SNM26_RS00090"
                     /old_locus_tag="SNM26_28715"
     CDS             9533..9886
                     /locus_tag="SNM26_RS00090"
                     /old_locus_tag="SNM26_28715"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_323811637.1"
                     /translation="MVDTSELFRVFGSLYGGGDTVKHAVKGDAGATGVNISGLHDLQHK
                     IALLEAENDGLKGAVKARDEHIDSLRQAMQLLENHQAKSNPLHRFIRRGGNSGKNPDPV
                     MLQFSSPAIPGSS"
                     /name="hypothetical protein"
     Typing          complement(1567..1974)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.39"
                     /coverage="99.0"
                     /evalue="1.26e-177"
     Typing          complement(5126..5533)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.39"
                     /coverage="99.0"
                     /evalue="1.26e-177"
     Typing          complement(8685..9092)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.154"
                     /coverage="99.0"
                     /evalue="2.76e-169"
ORIGIN
        1 cggggtatta taatgagcaa taaagattct ttagaaagaa aagtaacacc aagaaaaaat
       61 gaacctgtat tcccgatggc tctaagagtt gggatagctg aagatatttg ttttttagag
      121 ttagtggact ttcctgaaaa agaatcagga agggtttttt attccatagc tctaaccaaa
      181 aaacatgcaa agaaccttat cgatggattg aataaattcg ttgagtcagg tgattagtat
      241 gaaatacatt aaccactgcg atagtgaaga ttattatatt actaatgata gcattgatct
      301 cggtgttcgt tatgatgttt ctgattataa taagttagag ctaaatgatt taagagatcc
      361 ggatttgttt aaagttttgg gtcgagcatt tgttgttgtt gagaattctg tttgggagtc
      421 ttggaatgat gatgttaaaa cattagattg ctctggtgac ggttatgagt caattttaaa
      481 acattacgaa tcattagaat tatcaggtga attcttattg ttttttaaaa aaataagaag
      541 tgccatttct gtttataata gagaatacga gttctgcact ggtgacctag aaccatcttt
      601 gcaggctatt gttcagttga ttaggtatgc ccctgaactt gctgcaaaaa aagacgctca
      661 gatttacttt gataaaaaat cagagtgttt tgggcttata tataaacaaa ctaagaaaag
      721 caaaggcacg ctaaatttaa tagtgaaaac aaataacgag attatttttt cctttgttag
      781 aaaagtttct ggagtggtta aggttacagg tagggcatat attggcgata gccttgataa
      841 ctccattgct atcaaatcat tatttaaaat gatggagtgg tgatgactgt gttatcaact
      901 ttaaataacc tcaaatcaat cccttgtatt aatgcattta cgggcagagc aaataattca
      961 tatttatggc gttatgttat ggaagatcat aaagatgagt ttggcgctac aactattaag
     1021 tgtttttatc ttagggagga aatttcagag gattatgtgt ctatttatca ttcaaataaa
     1081 gattattatg aaggaatggt aagggatgta cataaaagaa tccctgtagg gaaaaccaaa
     1141 cctgccatat atctctcatt tgatgcagcg gaagtgatcg agcaagttaa caaaccagat
     1201 aaatgtattg atataaagga cgaaggttac cctcacttgg gtttgtggta tttatttgat
     1261 attaatgatg aatttacttt gattgaggtg actacaacta ttttggaatt atcctctttt
     1321 tttcaaagaa atgaaggtgg cgtggttgtt cctctttagc gaaaaccgtc ttgacgtcat
     1381 caagtgtgac ctagtactct tcttgaaaaa gaaaaaccgc ctttgcgggg cggtttttct
     1441 taggttctaa gagtttgcgg ctctatgaac caaggtaact ggctagttag aggagcgcag
     1501 taaccaaaat cgttctttca gtttagcctt aactggcaca taacttcaag actaactcct
     1561 ctaaatcagt taccagtggc tgctgccagt ggcgcttcgt cgtgtctttc cgggttggac
     1621 tcaagttgat agttaccgga aaaggcgcag cagtcggact gaacgggggg ttcgtgcata
     1681 cagtccagct tggagcgaac tgcctacccg gaactgagtg tcaggcgtgg aatgagataa
     1741 acgcggccat aacagcggaa tgacaccggt aaaccgaaag gcaggaacag gagagcgcac
     1801 gagggagcca ccagggggaa acgcctggta tctttatagt cctgtcgggt ttcgccacca
     1861 ctgatttgag cgtcagattt cgtgatgctt gtcagggggg cggagcctat ggaaaaacgg
     1921 ccgctgtgcg gcctctcctt ctccccatca cgcgatcgct cggttttctc gagcttttat
     1981 acgcatgctc ctgccgctcg ccgcagccga acggcaggag cgtagcgact gagtgagcga
     2041 ggaagcggaa aagagaacat ccctacactg agcactgacg ctctgaggcc tcttatgacg
     2101 aaacaacaga aaacagcgct gaacatggct aaattcatcc agaatcagtc tctgctcctg
     2161 ctggagaagc ttaacgagct tgatcttgat gtagaggccg acctttgtga gaaactccac
     2221 gatgatgcgg agcatctttt ccgtacactg tcttcgggac tggatgaatt acaggatgga
     2281 aactgatggc cagagtgtct attagtgaag cggctcggct tgttaaggtt agtcgcccca
     2341 caatttacaa gatgattaac agtgggaaac taagttacac ctctgttgta aagcatggga
     2401 aaaatactaa agttgttgat acatcagagc ttattagggt ttttggctcg ctttatggtg
     2461 ggggcgacac tgtaaaacat gatgtaaaag gtgacgcagg cgctacaggg gttaacatct
     2521 ctggtttaca tgatttacag cataaaattg ctttgcttga agctgaaaac gatggtctta
     2581 aaggggctgt taaagctcgt gatgaacata tcgattctct tcgccaggct atgcagcttc
     2641 tggaacacaa gctcgaaccc tctccacagg ttcattctcc gtggtggaaa ttctggaaga
     2701 aatcctgacc ccgtcatgct tcagttttcc tctccggcca ttccggggag ttcctgaacc
     2761 ttcccaaaaa tcgccagatc gctgaacgct cctcaccact aaaaatatcc acaccccacg
     2821 caaaattaaa attttgcaga tttgtatttt atatcagtag tttacgttct ataaatttcg
     2881 tttttttaat tttatttata cagatccgac tctatgacga ctcgtcatag agtccccggc
     2941 gagtcgtcat agagtcggta acgactcagg actataaaaa caataagtta acaacgaccc
     3001 gactctagac ccgactcccc gtttggttgt tttttagacg tgacgactct gggtacgact
     3061 ctagtgaaga gtcgccggtg aatcgtgtgg tgagtcgtcc ggcgacttgc cataacgtga
     3121 ttgccggccg tcgacgaacc cgattcctga acgtgctgaa aaccggtttt ccggctgcgc
     3181 cggcaacgct tcacggccac gcaataaatt gcgtccccgt tcaccgtttt cggatgggaa
     3241 gaacgccgga aacaggactt accctggctg aatagcgtga attttcgcgc tatgcacttg
     3301 cgtgcatact catgcatgcc gtaaaaacag agcctgcgcg tttctggcgg gttttcgggt
     3361 ggtttgttgc ctattttacc ggtttcccgt cagaaacgcc ctgaggccgt tttagcggtg
     3421 cgtacaattt tggtgttatg ttaaatcatg gccacaaaat tccataaagt gaccaatgta
     3481 atgttaaatg agcattgtgg atgaaagatg ttgttttatg gtattatttt ttatgttcta
     3541 aacttaaatt tatttctatc ggggtattat aatgagcaat aaagattctt tagaaagaaa
     3601 agtaacacca agaaaaaatg aacctgtatt cccgatggct ctaagagttg ggatagctga
     3661 agatatttgt tttttagagt tagtggactt tcctgaaaaa gaatcaggaa gggtttttta
     3721 ttccatagct ctaaccaaaa aacatgcaaa gaaccttatc gatggattga ataaattcgt
     3781 tgagtcaggt gattagtatg aaatacatta accactgcga tagtgaagat tattatatta
     3841 ctaatgatag cattgatctc ggtgttcgtt atgatgtttc tgattataat aagttagagc
     3901 taaatgattt aagagatccg gatttgttta aagttttggg tcgagcattt gttgttgttg
     3961 agaattctgt ttgggagtct tggaatgatg atgttaaaac attagattgc tctggtgacg
     4021 gttatgagtc aattttaaaa cattacgaat cattagaatt atcaggtgaa ttcttattgt
     4081 tttttaaaaa aataagaagt gccatttctg tttataatag agaatacgag ttctgcactg
     4141 gtgacctaga accatctttg caggctattg ttcagttgat taggtatgcc cctgaacttg
     4201 ctgcaaaaaa agacgctcag atttactttg ataaaaaatc agagtgtttt gggcttatat
     4261 ataaacaaac taagaaaagc aaaggcacgc taaatttaat agtgaaaaca aataacgaga
     4321 ttattttttc ctttgttaga aaagtttctg gagtggttaa ggttacaggt agggcatata
     4381 ttggcgatag ccttgataac tccattgcta tcaaatcatt atttaaaatg atggagtggt
     4441 gatgactgtg ttatcaactt taaataacct caaatcaatc ccttgtatta atgcatttac
     4501 gggcagagca aataattcat atttatggcg ttatgttatg gaagatcata aagatgagtt
     4561 tggcgctaca actattaagt gtttttatct tagggaggaa atttcagagg attatgtgtc
     4621 tatttatcat tcaaataaag attattatga aggaatggta agggatgtac ataaaagaat
     4681 ccctgtaggg aaaaccaaac ctgccatata tctctcattt gatgcagcgg aagtgatcga
     4741 gcaagttaac aaaccagata aatgtattga tataaaggac gaaggttacc ctcacttggg
     4801 tttgtggtat ttatttgata ttaatgatga atttactttg attgaggtga ctacaactat
     4861 tttggaatta tcctcttttt ttcaaagaaa tgaaggtggc gtggttgttc ctctttagcg
     4921 aaaaccgtct tgacgtcatc aagtgtgacc tagtactctt cttgaaaaag aaaaaccgcc
     4981 tttgcggggc ggtttttctt aggttctaag agtttgcggc tctatgaacc aaggtaactg
     5041 gctagttaga ggagcgcagt aaccaaaatc gttctttcag tttagcctta actggcacat
     5101 aacttcaaga ctaactcctc taaatcagtt accagtggct gctgccagtg gcgcttcgtc
     5161 gtgtctttcc gggttggact caagttgata gttaccggaa aaggcgcagc agtcggactg
     5221 aacggggggt tcgtgcatac agtccagctt ggagcgaact gcctacccgg aactgagtgt
     5281 caggcgtgga atgagataaa cgcggccata acagcggaat gacaccggta aaccgaaagg
     5341 caggaacagg agagcgcacg agggagccac cagggggaaa cgcctggtat ctttatagtc
     5401 ctgtcgggtt tcgccaccac tgatttgagc gtcagatttc gtgatgcttg tcaggggggc
     5461 ggagcctatg gaaaaacggc cgctgtgcgg cctctccttc tccccatcac gcgatcgctc
     5521 ggttttctcg agcttttata cgcatgctcc tgccgctcgc cgcagccgaa cggcaggagc
     5581 gtagcgactg agtgagcgag gaagcggaaa agagaacatc cctacactga gcactgacgc
     5641 tctgaggcct cttatgacga aacaacagaa aacagcgctg aacatggcta aattcatcca
     5701 gaatcagtct ctgctcctgc tggagaagct taacgagctt gatcttgatg tagaggccga
     5761 cctttgtgag aaactccacg atgatgcgga gcatcttttc cgtacactgt cttcgggact
     5821 ggatgaatta caggatggaa actgatggcc agagtgtcta ttagtgaagc ggctcggctt
     5881 gttaaggtta gtcgccccac aatttacaag atgattaaca gtgggaaact aagttacacc
     5941 tctgttgtaa agcatgggaa aaatactaaa gttgttgata catcagagct tattagggtt
     6001 tttggctcgc tttatggtgg gggcgacact gtaaaacatg atgtaaaagg tgacgcaggc
     6061 gctacagggg ttaacatctc tggtttacat gatttacagc ataaaattgc tttgcttgaa
     6121 gctgaaaacg atggtcttaa aggggctgtt aaagctcgtg atgaacatat cgattctctt
     6181 cgccaggcta tgcagcttct ggaacacaag ctcgaaccct ctccacaggt tcattctccg
     6241 tggtggaaat tctggaagaa atcctgaccc cgtcatgctt cagttttcct ctccggccat
     6301 tccggggagt tcctgaacct tcccaaaaat cgccagatcg ctgaacgctc ctcaccacta
     6361 aaaatatcca caccccacgc aaaattaaaa ttttgcagat ttgtatttta tatcagtagt
     6421 ttacgttcta taaatttcgt ttttttaatt ttatttatac agatccgact ctatgacgac
     6481 tcgtcataga gtccccggcg agtcgtcata gagtcggtaa cgactcagga ctataaaaac
     6541 aataagttaa caacgacccg actctagacc cgactccccg tttggttgtt ttttagacgt
     6601 gacgactctg ggtacgactc tagtgaagag tcgccggtga atcgtgtggt gagtcgtccg
     6661 gcgacttgcc ataacgtgat tgccggccgt cgacgaaccc gattcctgaa cgtgctgaaa
     6721 accggttttc cggctgcgcc ggcaacgctt cacggccacg caataaattg cgtccccgtt
     6781 caccgttttc ggatgggaag aacgccggaa acaggactta ccctggctga atagcgtgaa
     6841 ttttcgcgct atgcacttgc gtgcatactc atgcatgccg taaaaacaga gcctgcgcgt
     6901 ttctggcggg ttttcgggtg gtttgttgcc tattttaccg gtttcccgtc agaaacgccc
     6961 tgaggccgtt ttagcggtgc gtacaatttt ggtgttatgt taaatcatgg ccacaaaatt
     7021 ccataaagtg accaatgtaa tgttaaatga gcattgtgga tgaaagatgt tgttttatgg
     7081 tattattttt tatgttctaa acttaaattt atttctatcg gggtattata atgagcaata
     7141 aagattcttt agaaagaaaa gtaacaccaa gaaaaaatga acctgtattc ccgatggctc
     7201 taagagttgg gatagctgaa gatatttgtt ttttagagtt agtggacttt cctgaaaaag
     7261 aatcaggaag ggttttttat tccatagctc taaccaaaaa acatgcaaag aaccttatcg
     7321 atggattgaa taaattcgtt gagtcaggtg attagtatga aatacattaa ccactgcgat
     7381 agtgaagatt attatattac taatgatagc attgatctcg gtgttcgtta tgatgtttct
     7441 gattataata agttagagct aaatgattta agagatccgg atttgtttaa agttttgggt
     7501 cgagcatttg ttgttgttga gaattctgtt tgggagtctt ggaatgatga tgttaaaaca
     7561 ttagattgct ctggtgacgg ttatgagtca attttaaaac attacgaatc attagaatta
     7621 tcaggtgaat tcttattgtt ttttaaaaaa ataagaagtg ccatttctgt ttataataga
     7681 gaatacgagt tctgcactgg tgacctagaa ccatctttgc aggctattgt tcagttgatt
     7741 aggtatgccc ctgaacttgc tgcaaaaaaa gacgctcaga tttactttga taaaaaatca
     7801 gagtgttttg ggcttatata taaacaaact aagaaaagca aaggcacgct aaatttaata
     7861 gtgaaaacaa ataacgagat tattttttcc tttgttagaa aagtttctgg agtggttaag
     7921 gttacaggta gggcatatat tggcgatagc cttgataact ccattgctat caaatcatta
     7981 tttaaaatga tggagtggtg atgactgtgt tatcaacttt aaataacctc aaatcaatcc
     8041 cttgtattaa tgcatttacg ggcagagcaa ataattcata tttatggcgt tatgttatgg
     8101 aagatcataa agatgagttt ggcgctacaa ctattaagtg tttttatctt agggaggaaa
     8161 tttcagagga ttatgtgtct atttatcatt caaataaaga ttattatgaa ggaatggtaa
     8221 gggatgtaca taaaagaatc cctgtaggga aaaccaaacc tgccatatat ctctcatttg
     8281 atgcagcgga agtgatcgag caagttaaca aaccagataa atgtattgat ataaaggacg
     8341 aaggttaccc tcacttgggt ttgtggtatt tatttgatat taatgatgaa tttactttga
     8401 ttgaggtgac tacaactatt ttggaattat cctctttttt tcaaagaaat gaaggtggcg
     8461 tggttgttcc tctttagcga aaaccgtctt gacgtcatca agtgtgacct agtactcttc
     8521 ttgaaaaaga aaaaccgcct tgcagggcgg ttttttctaa ggttctaaaa acttgcaggt
     8581 ctttgaaccg aggtagctgg ctagttggag gagcgcagtc accaaaactg ttcttttagt
     8641 ttagcctcaa ctggcgcata acttcaagac taactcctct aaatcagtta ccagtggctg
     8701 ctgccagtgg cgctttgtcg tgtctttccg ggttggactc aagttgatag ttaccggaca
     8761 aggcgcagca gtcggactga acggggggtt cgtgcataca gtccagcttg gagcgaactg
     8821 cctacccgga actgagtgtc aggcgtggaa tgagataaac gcggccataa cagcggaatg
     8881 acaccggcaa accgaatggc aggaacagga gagcgcacga gggagccatc agggggaaac
     8941 gcctggtatc tttaaagtcc tgtcgggttt cgccaccact gatttgagcg tcagtttctg
     9001 tgatgcttgt caggggggcg aagcctatgg aaaaagggcc gccacgcggc ctttcctttt
     9061 tttcatcacg ctattgatcg gttttctcga gcttttctac gcatgctcct gccgctcgcc
     9121 gcagccgaac ggcaggagcg tagcgactga gtgagcgagg aagcggaaaa gagaacaccc
     9181 ttacactgag cactgacgct ctgaggcctc ttatgactaa acaacagaaa acagcgctga
     9241 acatggctaa attcatccag aatcagtctc tgctcctgct ggagaagctt aacgagcttg
     9301 acctcgatgt agaggccgac ctttgtgaga aactccacga tgatgcggag catcttttcc
     9361 gtacactgtc cttgagactg gatgcattac aggatggtaa ctgatggcca gagtgtctat
     9421 tagtgaggct gcccgactga cgggtaagag tagaacaaca ctgcacaggt taattaaagc
     9481 agtgggaacc tagttccacc tctgttgtaa agcatggtga acaaatacaa aagtggtaga
     9541 tacttcagag ctttttcgtg tctttggctc cctttatggt gggggcgaca ctgtaaaaca
     9601 tgctgtaaaa ggtgacgcag gcgctacagg ggttaacatc tctggtttac atgatttaca
     9661 gcataaaatt gctttgcttg aagctgaaaa cgatggtctt aaaggggctg ttaaagctcg
     9721 tgatgaacat atcgattctc ttcgccaggc tatgcagctt ctggaaaatc accaagcaaa
     9781 atcgaaccct ctccacaggt tcattcgccg tggtggaaat tctggaaaaa atcctgaccc
     9841 cgtcatgctt cagttttcct ctccggccat tccggggagt tcctgaacct tcccaaaaat
     9901 tgtcagatct ctgaacgctc ctcaccacta aaaataccca caccccacgc aaaattaaca
     9961 ttttgcagat ttgtatttaa tatcagtggg ttactttcct gaaatttcgt tttttaaatt
    10021 ttatttatat agatccgact ctatgacgag tcgtcataga gtccccggcg agtcgtcata
    10081 gagtcggtaa cgactcagga ctataaaaac aataagttaa caacgacccg actctagaca
    10141 cgactccccg tttggttgtt ttttagacgt ggcgactctg ggtacgactc tagtgaagag
    10201 tcgccggtga atcgtgtggt gagtcgtccg gcgacttgcc ataacgtgat tgccggccgt
    10261 cgacgaaccc gattcctgaa cgtgctgaaa accggttttc cggctgcgcc ggcaacgctt
    10321 cacggccacg caataaattg cgtccccgtt caccgttttc ggatgggaag aacgccggaa
    10381 acaggactta ctctggctga atggcgtgaa ttttcgcgct atgcacttgc gtgcatactc
    10441 atgcatgccg taaaaacaga gcctgcgcgt ttctggcggg ttttcgggtg gtttgttgcc
    10501 tattttaccg gtttcccgtc agaaacgccc tgaggccgtt ttagcggtgc gtacaatttg
    10561 ggtgttatgt taaatcatgg ccacaaaatt ccataaagtg accaatgtaa tgttaaatga
    10621 gcattgtgga tgaaagatgt tgttttatgg tattattttt tatgttctaa acttaaattt
    10681 atttctat
//
