LOCUS       NZ_CP140467            27742 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Escherichia coli strain GZ04-0083 plasmid p0083-27kb, complete
            sequence.
ACCESSION   NZ_CP140467
VERSION     NZ_CP140467.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38608631
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27742)
  AUTHORS   Lu,L.
  TITLE     Genomic characterization of a novel multidrug-resistant plasmid
            harboring blaNDM5 in Escherichia coli sequence type 167 isolate from
            Zhongshan, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27742)
  AUTHORS   Lu,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) Department of Laboratory Medicine, Zhongshan
            City People's Hospital, 2nd Sunwendong Road, Zhongshan, Guangdong
            528403, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 310.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/08/2024 10:30:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 38
            CDSs (total)                      :: 38
            Genes (coding)                    :: 37
            CDSs (with protein)               :: 37
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 1
            CDSs (without protein)            :: 1
            Pseudo Genes (ambiguous residues) :: 0 of 1
            Pseudo Genes (frameshifted)       :: 0 of 1
            Pseudo Genes (incomplete)         :: 1 of 1
            Pseudo Genes (internal stop)      :: 0 of 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP140467.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27742
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="GZ04-0083"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p0083-27kb"
                     /geo_loc_name="China: Zhongshan, Guangdong Province"
                     /collection_date="2018"
                     /genotype="ST167"
     gene            complement(join(27430..27742,1..152))
                     /locus_tag="U3886_RS00005"
                     /old_locus_tag="U3886_23190"
     CDS             complement(join(27430..27742,1..152))
                     /locus_tag="U3886_RS00005"
                     /old_locus_tag="U3886_23190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_112920254.1"
                     /translation="MNILIIFALCILSSSPYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYERYNTDNDLATLQQEARSQKRGLWADPNPVPPWEWRHK"
                     /name="thermonuclease family protein"
     gene            complement(156..890)
                     /gene="mobC"
                     /locus_tag="U3886_RS00010"
                     /old_locus_tag="U3886_23195"
     CDS             complement(156..890)
                     /gene="mobC"
                     /locus_tag="U3886_RS00010"
                     /old_locus_tag="U3886_23195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_112920255.1"
                     /translation="MLIHDFHERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RSPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGIIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDEKNREMFIFRTIDELEQ"
                     /name="mobC"
     gene            complement(902..2629)
                     /locus_tag="U3886_RS00015"
                     /old_locus_tag="U3886_23200"
     CDS             complement(902..2629)
                     /locus_tag="U3886_RS00015"
                     /old_locus_tag="U3886_23200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_001350940.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDMPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(3439..3744)
                     /locus_tag="U3886_RS00020"
                     /old_locus_tag="U3886_23205"
     CDS             complement(3439..3744)
                     /locus_tag="U3886_RS00020"
                     /old_locus_tag="U3886_23205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dpoa decarboxylase"
                     /protein_id="WP_112920237.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     RLMRGVIEHTAKLKISDANKLISYAASQGYEITEDRYNAAIKAEDECLAEITRAQV"
                     /name="dpoa decarboxylase"
     gene            complement(3772..3987)
                     /locus_tag="U3886_RS00025"
                     /old_locus_tag="U3886_23210"
     CDS             complement(3772..3987)
                     /locus_tag="U3886_RS00025"
                     /old_locus_tag="U3886_23210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920238.1"
                     /translation="MDTDKNMVFYLTNSDLVYSYAHKIVHSIPSGMKGKFITSIGETIE
                     DLKKRHPDITLITESEALALQSERKN"
                     /name="hypothetical protein"
     gene            complement(3990..4289)
                     /locus_tag="U3886_RS00030"
                     /old_locus_tag="U3886_23215"
     CDS             complement(3990..4289)
                     /locus_tag="U3886_RS00030"
                     /old_locus_tag="U3886_23215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_112920239.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGSEC
                     RSAEKAFFNIIKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(4319..4717)
                     /locus_tag="U3886_RS00035"
                     /old_locus_tag="U3886_23220"
     CDS             complement(4319..4717)
                     /locus_tag="U3886_RS00035"
                     /old_locus_tag="U3886_23220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_112920240.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNEKLPEWNPN
                     SLIIKSPVINDKWTLSISSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFIAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(4714..5739)
                     /gene="virB11"
                     /locus_tag="U3886_RS00040"
                     /old_locus_tag="U3886_23225"
     CDS             complement(4714..5739)
                     /gene="virB11"
                     /locus_tag="U3886_RS00040"
                     /old_locus_tag="U3886_23225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_112920241.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYNSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNIRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            complement(5752..5919)
                     /locus_tag="U3886_RS00045"
                     /old_locus_tag="U3886_23230"
     CDS             complement(5752..5919)
                     /locus_tag="U3886_RS00045"
                     /old_locus_tag="U3886_23230"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223424526.1"
                     /translation="MNCKDKEIWLHMLAAGHMGVLAGNPNEAAAQDAYQRLIKSKTTLA
                     VYSSAPPESR"
                     /name="hypothetical protein"
     gene            complement(5903..7168)
                     /gene="virB10"
                     /locus_tag="U3886_RS00050"
                     /old_locus_tag="U3886_23235"
     CDS             complement(5903..7168)
                     /gene="virB10"
                     /locus_tag="U3886_RS00050"
                     /old_locus_tag="U3886_23235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_112920242.1"
                     /translation="MTDENKSPSTEEEKPVTTSDQDDIATLEREARAKREAELQASQDD
                     EKENSLQPAVNKLKKRQKGKATAFLAICAVALIGLTWGGNWVYQNFLKQEDGEKTKEVT
                     PPKKTNDYRKRTDLGMATNEPENSTDGEQAVSQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGKIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRMKNELQR"
                     /name="virB10"
     gene            complement(7210..8115)
                     /gene="virB9"
                     /locus_tag="U3886_RS00055"
                     /old_locus_tag="U3886_23240"
     CDS             complement(7210..8115)
                     /gene="virB9"
                     /locus_tag="U3886_RS00055"
                     /old_locus_tag="U3886_23240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_112920243.1"
                     /translation="MRKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQAQIQKALRTAQTPRNWDYTKYPGKDSYSIEPDFAYDDGRFTFIGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQDITPRLVLRSGDAVVGLKNNGFGKVH
                     AADNSTVSNKVERVEKTDNT"
                     /name="virB9"
     gene            complement(8115..8798)
                     /locus_tag="U3886_RS00060"
                     /old_locus_tag="U3886_23245"
     CDS             complement(8115..8798)
                     /locus_tag="U3886_RS00060"
                     /old_locus_tag="U3886_23245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000139289.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLIAILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            complement(8984..10054)
                     /locus_tag="U3886_RS00065"
                     /old_locus_tag="U3886_23255"
     CDS             complement(8984..10054)
                     /locus_tag="U3886_RS00065"
                     /old_locus_tag="U3886_23255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_029397044.1"
                     /translation="MSGGVFVGVEKHLIGGITDATQGLMMSYSSMMMGLAGTSATIYII
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGLKEGFSSSSSI
                     WQLLDTLWHNAKVLGKTLHDLDDSEFIKDEGTIAELFVWGGVFVLMIITAFVSMVAEVM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAGILTILLSSLSLRIVISYLNSRLALA
                     SSGANQANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     STPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            complement(10063..10290)
                     /locus_tag="U3886_RS00070"
                     /old_locus_tag="U3886_23260"
     CDS             complement(10063..10290)
                     /locus_tag="U3886_RS00070"
                     /old_locus_tag="U3886_23260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_029397045.1"
                     /translation="MRLLTITLLSLSAFLINGCEEEAKTTKWYRTHPDELKAVYEKCQK
                     TGSASENCKHANEAHWQIQQLNAPTVDLNQ"
                     /name="EexN family lipoprotein"
     gene            complement(10300..11007)
                     /locus_tag="U3886_RS00075"
                     /old_locus_tag="U3886_23265"
     CDS             complement(10300..11007)
                     /locus_tag="U3886_RS00075"
                     /old_locus_tag="U3886_23265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001615551.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLAEERRKKWN
                     QQQLNAPTLDLNS"
                     /name="type IV secretion system protein"
     gene            complement(11022..13766)
                     /locus_tag="U3886_RS00080"
                     /old_locus_tag="U3886_23270"
     CDS             complement(11022..13766)
                     /locus_tag="U3886_RS00080"
                     /old_locus_tag="U3886_23270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_112920244.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLFLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLITHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLVADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDARTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(13779..14075)
                     /locus_tag="U3886_RS00085"
                     /old_locus_tag="U3886_23275"
     CDS             complement(13779..14075)
                     /locus_tag="U3886_RS00085"
                     /old_locus_tag="U3886_23275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_001615548.1"
                     /translation="MFNKLKTICSRASAYILAPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            complement(14079..14783)
                     /locus_tag="U3886_RS00090"
                     /old_locus_tag="U3886_23280"
     CDS             complement(14079..14783)
                     /locus_tag="U3886_RS00090"
                     /old_locus_tag="U3886_23280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_094283541.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTKDDIATQSAILNATPVEAPARPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(14799..15005)
                     /locus_tag="U3886_RS00095"
                     /old_locus_tag="U3886_23285"
     CDS             complement(14799..15005)
                     /locus_tag="U3886_RS00095"
                     /old_locus_tag="U3886_23285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920245.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNEKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     gene            complement(15006..15218)
                     /locus_tag="U3886_RS00100"
                     /old_locus_tag="U3886_23290"
     CDS             complement(15006..15218)
                     /locus_tag="U3886_RS00100"
                     /old_locus_tag="U3886_23290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001133545.1"
                     /translation="MPNPIGQAKSTAVIYIGKKRYETLAKHARDISYVAEVNIRPSAFL
                     QYMIDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            complement(15295..15774)
                     /locus_tag="U3886_RS00105"
                     /old_locus_tag="U3886_23295"
     CDS             complement(15295..15774)
                     /locus_tag="U3886_RS00105"
                     /old_locus_tag="U3886_23295"
                     /inference="COORDINATES: protein motif:HMM:NF014417.4"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_001615545.1"
                     /translation="MGACVRKVTLMNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIK
                     FTPRKDCNAVRKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKV
                     VIAIKCAKILALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            15964..16365
                     /locus_tag="U3886_RS00110"
                     /old_locus_tag="U3886_23300"
     CDS             15964..16365
                     /locus_tag="U3886_RS00110"
                     /old_locus_tag="U3886_23300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_307873364.1"
                     /translation="MFWKTKQGDRSMVPKRLKEAREAAGLSQEKLSELVGIEGTSTRSR
                     MSNYEAGRFTPPFKFICRVADVLGYPEYYFYIVNDVTAKKLLQMYKGEKNSIENIELEA
                     SRMADQLDDARKLVSQLSDCVRELKRSLG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            16932..17657
                     /locus_tag="U3886_RS00115"
                     /old_locus_tag="U3886_23305"
     CDS             16932..17657
                     /locus_tag="U3886_RS00115"
                     /old_locus_tag="U3886_23305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172001.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_001312457.1"
                     /translation="MRAVVAEKNNSLIPRISPSGVAKQSPCYNVVSRKRRRFLNRWIKS
                     LTTVAGRIKIKNELRRRIRHNRYWVNEANKFGIEALCELMLAILDDLDLRSWETRHNLE
                     TLAERAGLVTRSDAGHKSISRASRGCDRLVWLNAIITEKAPFNPYDARCACKHIEVTED
                     FFAILGIPLKLVYRERARLLKADPDEVIYSGDARLIAIRVQNWTRKAAAGLARMKAKRD
                     AARQRKKEYYAHSPTPIPA"
                     /name="RepA family replication protein"
     gene            18614..18886
                     /locus_tag="U3886_RS00120"
                     /old_locus_tag="U3886_23310"
     CDS             18614..18886
                     /locus_tag="U3886_RS00120"
                     /old_locus_tag="U3886_23310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920246.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTNQEGT
                     KFLSTLQEITTELDALIDAVESHSPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            18960..19259
                     /locus_tag="U3886_RS00125"
                     /old_locus_tag="U3886_23315"
     CDS             18960..19259
                     /locus_tag="U3886_RS00125"
                     /old_locus_tag="U3886_23315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920247.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGKKYIVVFTDNNK
                     IRDYKNGVIEELGEIMQEDIELIEYYAKKYEKYFDNLKIGEEPLNLKEYIECMQ"
                     /name="hypothetical protein"
     gene            19630..20163
                     /locus_tag="U3886_RS00130"
                     /old_locus_tag="U3886_23320"
     CDS             19630..20163
                     /locus_tag="U3886_RS00130"
                     /old_locus_tag="U3886_23320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_112920248.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKDAFKKAALKYHPDRNPVGAEMMK
                     AANSAFDFLMANLDKINQYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEYKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="J domain-containing protein"
     gene            20291..20833
                     /locus_tag="U3886_RS00135"
                     /old_locus_tag="U3886_23325"
     CDS             20291..20833
                     /locus_tag="U3886_RS00135"
                     /old_locus_tag="U3886_23325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920249.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTEFRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANAPDEIELL
                     RGHESALQEKQDKVRIIKGMLSQLLSISPWYGALTGFNADNGLAGKILQNGDDYEMVIR
                     GLNVEQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            20858..21127
                     /locus_tag="U3886_RS00140"
                     /old_locus_tag="U3886_23330"
     CDS             20858..21127
                     /locus_tag="U3886_RS00140"
                     /old_locus_tag="U3886_23330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920250.1"
                     /translation="MGLFMKTDNVFFKSKGSYSYVITVDMDNQVYMVRKYVKTYVKSCD
                     KEQVKGKKTVKKLVLDTNLTLPELLSLDNGILADLFTRGNNNAN"
                     /name="hypothetical protein"
     gene            21117..21356
                     /locus_tag="U3886_RS00145"
                     /old_locus_tag="U3886_23335"
     CDS             21117..21356
                     /locus_tag="U3886_RS00145"
                     /old_locus_tag="U3886_23335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_112920251.1"
                     /translation="MQTKPTPADVKEARVSAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTVGILNN"
                     /name="hypothetical protein"
     gene            complement(21589..22293)
                     /locus_tag="U3886_RS00150"
                     /old_locus_tag="U3886_23340"
     CDS             complement(21589..22293)
                     /locus_tag="U3886_RS00150"
                     /old_locus_tag="U3886_23340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067858.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            22476..23525
                     /gene="cfr"
                     /locus_tag="U3886_RS00155"
                     /old_locus_tag="U3886_23345"
     ARG             22477..23522
                     /name="cfr"
                     /gene="cfr"
                     /gene_name="23S rRNA (adenine(2503)-C(8))-methyltransferase
                     Cfr"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/LINCOSAMIDE/OXAZOLIDINONE/PLEUROMUTIL
                     IN/STREPTOGRAMIN"
                     /identity="99.71"
                     /coverage="100.0"
     gene            complement(23611..24315)
                     /locus_tag="U3886_RS00160"
                     /old_locus_tag="U3886_23350"
     CDS             complement(23611..24315)
                     /locus_tag="U3886_RS00160"
                     /old_locus_tag="U3886_23350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067858.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            24596..24880
                     /locus_tag="U3886_RS00165"
                     /old_locus_tag="U3886_23355"
     CDS             24596..24880
                     /locus_tag="U3886_RS00165"
                     /old_locus_tag="U3886_23355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_024227107.1"
                     /translation="MAKPKSEIDAIRALTEVTIKGFEQIVQALDDTREAQGKVARATYN
                     GLTSSGKSRYVASLVKEVGSQAEVSRMLNITPGRVSQLMKSEKNRKNGK"
                     /name="hypothetical protein"
     gene            complement(24914..25213)
                     /locus_tag="U3886_RS00170"
                     /old_locus_tag="U3886_23360"
     CDS             complement(24914..25213)
                     /locus_tag="U3886_RS00170"
                     /old_locus_tag="U3886_23360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_112920252.1"
                     /translation="MRTLEEVIASRSPESQARIKEMADEMILEVGLQMMREELQLSQKQ
                     VAEAMGISQPAVTKLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFHV"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(25213..25560)
                     /locus_tag="U3886_RS00175"
                     /old_locus_tag="U3886_23365"
     CDS             complement(25213..25560)
                     /locus_tag="U3886_RS00175"
                     /old_locus_tag="U3886_23365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_025667955.1"
                     /translation="MWTVLFSQRFDDWLNEQEDALQEKVLADLKNLQVYGPELPRPYAD
                     TVKGSRYKNMKELRVQFSGRPIRAFYAFDPIRRAIVLCAGDKSNDKRFYKKLVRIAEDE
                     FAAHLNTLESK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            25829..26572
                     /locus_tag="U3886_RS00180"
                     /old_locus_tag="U3886_23370"
     CDS             25829..26572
                     /locus_tag="U3886_RS00180"
                     /old_locus_tag="U3886_23370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_323848148.1"
                     /translation="MPPVVQIVVAILGTNTDTIIIFFYKNIFIGGRMTVAIALVNGKGG
                     VKKSSMSRAIATEYTKADWKVLGLDMDVDQGSFLDWGQRRLRYKVEPPVTIQGCGTVSQ
                     AKKHIESGIWDLVVIDSAAYATKSLLSLAEIVDLLVLPSGFSVDDLRTTVTTVNALRNK
                     GYSTNKMAVVFVGVSESESEYRTALEYLKPCGVQVINGAIPFMTSFSQAQDKGLALTES
                     PFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     gene            26612..26845
                     /locus_tag="U3886_RS00185"
                     /old_locus_tag="U3886_23375"
     CDS             26612..26845
                     /locus_tag="U3886_RS00185"
                     /old_locus_tag="U3886_23375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001615564.1"
                     /translation="MANVPPKPRNTKGEPPSLEDTQYGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(<27115..27420)
                     /locus_tag="U3886_RS00190"
                     /old_locus_tag="U3886_23380"
                     /pseudo=""
     CDS             complement(<27115..27420)
                     /locus_tag="U3886_RS00190"
                     /old_locus_tag="U3886_23380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     ARG             22477..23525
                     /name="cfrA"
                     /gene="cfrA"
                     /gene_name="Cfr 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic; streptogramin
                     antibiotic; streptogramin A antibiotic; oxazolidinone
                     antibiotic; phenicol antibiotic; pleuromutilin antibiotic"
                     /identity="99.71"
                     /coverage="100.0"
     Typing          complement(160..890)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="7.77e-164"
     Typing          complement(8119..8798)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.903"
                     /coverage="100.0"
                     /evalue="3.86e-119"
     Typing          complement(11026..13766)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.527"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttggccagac gaatcctcac tggtgtttta ttctgtaaaa tttcgatggt atcgccgtca
       61 agtacacgaa taacttttcc ctgtatatcc gctgcattgg catatggtga agacgacaag
      121 atacatagtg cgaatatgat taatatattc atcaactatt gttccagttc atcaattgtt
      181 ctaaaaataa acatttctct gtttttctca tcaaaaggca caggtgtatt attcctcatt
      241 acagttttga ttgagtcgaa tagtctgatt aatgattctt tacttttggt gtcaggcatg
      301 acgtacaaag cataatgcca gtttccttta tctcttgccg taagatgact gtttataatg
      361 cttatataac gagcacgagt tttcattgtt cgttctgttt caatagccat gattgcgcca
      421 gttggttgtt ttattattcc atccgggcga tgggaacagc cggagtaacg tgcgatgaag
      481 gctgcactat caccgttaat ccattcagta gcgcctttac tttccagaga tattctcact
      541 cgctgattta aaagacgatg ttcaagagtc cagtatttta gtttgctggg ttcaaaataa
      601 ctagggaacg taatgtcatc ggcttttaca accattgcta atccttgcat agtaataccc
      661 caaacagtta attttctttt tgatgatggt atttcatgtt tgataataaa accttcttta
      721 agagccttgt ttagtaattt atatactggg cttctgcttt tttttgtgaa tcctaatttt
      781 cttttgataa tgtgaaagtc tgaataggtt tcatccttaa ggaaatttaa aaggcaaagc
      841 atgttgttag ctgatattct ttttctttcg tgaaaatcat gaattaacat atagtaaaac
      901 ctcataaacc actggaaggc atatcgttgt tattgtgttg ttctatttgt tctgtctcaa
      961 aagatagcaa ttcaatggtt tctttgtttg ctggtatatg agacatttta gttgcttttg
     1021 gtaaatcttt tgatgtgaac acaaatccta ctctttcagg tagatttaaa aacatattac
     1081 tgtctacata ataactttct gcctgtctta tcatgcggtc agtatcaact ttttctgtta
     1141 atgataagtc ggttcttacc ttcctcattt catcgtcaac taatatggaa ccagtcattt
     1201 tagctgccca ctctgctgtt tctggattct ggattttata gattaacttg aattttgcgt
     1261 tttcaataac agcaccaatt acagaatcgc cattaagatc agaaggacaa tctcttaaat
     1321 catctattgc ctggaaggcc ataaatatat gcacactttt atctcgtgct gtacctaatc
     1381 cttccattgt tgggcgtgaa atatgatatt tcaactcatc aaggaaaatt gcaacaacac
     1441 gtggtgttgt gtttattctg tctctggttt cagctatttg aatcaaacgc gtaagtatca
     1501 tgcgttgtgc agaaataatt ttttgatttc gggttgaccc aatgatatag cagcatcctc
     1561 cattatcaaa aatctcttta agagaaaaac cattttttgc attgacggaa tttacaagag
     1621 cgatttcttc tagttcacct aaaaatgctg gggcatcttc tcctattgat tttacgttgt
     1681 catcgttgaa taaatcatac agtgtcattc ctgttttatg aattgcggct acatttctgg
     1741 ctgcgcggcg atcagctata cgataaaaat ctgcggcctc tccttttttt gatagactaa
     1801 atcctgcgtt aaataattct tctaattgtt catgtgatat gtcagccagt aagtcaagtt
     1861 gatggttggt tctgtttaaa ttaattacaa caaatttctt tcctgctttt ttacatgctt
     1921 ctctaagaac atgcacagcc cattcatcat cttttggatc ttcaacaaaa acagcctcgc
     1981 ctaatagaat tgcctgataa agcaaaaccg atgcggtaat gcccttacct gaacctgttg
     2041 tacctatgat tgctgcatgt tgtttctgaa attcttttat tgttatatat tgcggttggt
     2101 cgtctttgtc taagccaatg aaaacccctt ttttcaaatc aatgtaatct agaggattgt
     2161 attctatgct gtctggcaac aattctttta ctttgcgaac atctgttctt gtatttctct
     2221 caagtttgct tttctttatc attctgtgtt tcagactgtc tatttcacct gctaataatc
     2281 gtctcgctgt caaatgaaaa gctaatccgg ctagtgtaaa gagaatagtg attatccata
     2341 atggtattct aagtagtgta tttggatcga gaacgtcaaa gagataactc agtccatgaa
     2401 tactaagtgg tgacattgtt ccaaatatga aaaagaaaat ggacacgcac gcaacagatt
     2461 ttaaccagaa gggagcgttt tttctttcct ctcgtggtag gttgaatata aatggaagtg
     2521 ttagtcctgc cagtaatgac aatatgacag ggctgttctg tagccataac agaaatattg
     2581 aaaaagcatc agcaatacca tttagctttt gcattagatg tggattcata tttattttcc
     2641 ccattcataa agtgaatcta tggggtacga caatggggta cagtaatggg ggatataatg
     2701 taccccatag ctgtacccca ttattgtacc ccaataaaag ccaaaaacgt tgtgatcgcc
     2761 taaggcgatc atgcccgtta tccgttcttt cagaatccag ccgataagtt atcgtctggc
     2821 tcctgaaagc ccgaataacg ggcaacggcg tgtgccgttt cggcctggct ggaacgccag
     2881 tccttcacgt cacatggggg taatggcccg tctggacgcc ggaccaaaac ccccaaggtc
     2941 aaaggcggca caccgtcgcg cgctacgcgc gaccaccccc tttaagacgc gcgtttagcc
     3001 tattttttct tcgcaagctc gaaaaaattg gaacgctgct ttaaaggggg tggtcgcgcc
     3061 taatcggtaa tatcccccgc tggggcggga aatattacct ggcccgacgg tgtgcggggc
     3121 aagcccccca caaaaaccgg cacgtgggcg tgcctttttt ctcgctgggg cggaaaaatt
     3181 tttgcggctc cccccggccc gcttcaattc gcttggggcg aatgttcgcg ggtgggcgtg
     3241 gtgcctgaaa attaacaatt tcttcgaaat tgaattttct gtccacgcac cactttcttt
     3301 attcctgtct taacaatttc ttcgaaattg aagccagaaa taaagaaagc ctgaactgca
     3361 ccacgccctg cgtcggactc gcccaaattc gcaaagcgaa tttgccccgc ccttcgggtt
     3421 gctacgcaat cctctgcctc agacttgtgc ccgtgttatt tcagccagac attcatcctc
     3481 ggcttttatt gctgcattat atctgtcttc tgttatttca taaccttgtg aagcagcgta
     3541 actaatcagc ttattggcat cagaaatttt cagtttcgct gtgtgttcaa ttacccctcg
     3601 cattaacctc gcttgatata tttcataata tagtccgcat cccctgtttg ctttattact
     3661 aatgtcatca aagactcttt ttacatggat tctgtcctga ttccttgaat gaatattatt
     3721 aatgaacata tcttctttta acataggatt ctccagattt gaaaaaatat gttaattttt
     3781 tctctccgat tgcaatgcta atgcttcaga ttctgtaatg agagtaatat cagggtgtcg
     3841 tttctttaaa tcttcaatcg tttcaccaat agaagtaatg aattttcctt tcattcctga
     3901 tggaatggag tgtactatct tgtgtgcata gctataaaca agatcggagt ttgtcagata
     3961 aaataccatg tttttatctg tatccatatt tatcctcgga ctctaccaaa cttactcatt
     4021 atttttgata tggctgcggg atcggctgat gaacactgat ttaaaaatgc tttacgtgca
     4081 tcaaatgttt tactccatcg tattgaacct ttcttcttct taataatatt gaagaatgct
     4141 ttttctgctg atctgcattc gctacctccg ctgtttcctg tagcttttcc gtacatacat
     4201 aaaacaacct cgcatgggtc tgcggcataa gagtaaacag gtgtggcggt tgttaaaaca
     4261 aacattgtta ttgctgctat ttttttcatg tcagaaccct ttgtttaata tatttgtgtt
     4321 aacgcgaaaa gtagatggtt gtttcattgc acgtaagaca atttgtgatg gggtgatata
     4381 taattacccc gtttgcacca tgatgataca accagttttt tgcgatgaaa tagtcagcgc
     4441 ctgactttgt tgctactgtg atttgtgttg agtgagcaat ggcataaaag acagatggca
     4501 tccaatcttc tttattgaaa tcttgtgagc taatggataa agtccattta tcattaataa
     4561 caggcgattt tattattaag ctattggggt tccattcagg aagtttctcg ttaagcgata
     4621 ccggcttttt attccattcc acgggtactg gtggaggcgg tgaggaacat ccggtaatta
     4681 gtgttacaag cacagtaacc agtatatgct ttatcatact ttcatttcct cgtaatattg
     4741 attgcggtgt aacggtcgga aataaatatc attcatacgg cgtatgtttc catctaaatc
     4801 aatgctcaca acaacatcca gagagtcgag aactttacgt agcaagaatg aatatggtaa
     4861 ttgcgcacac tgtgggtttt cagtacagcg ggtaataaaa ccgtcgattg cttcatgggc
     4921 tgaaccagca tgaatggagg tcatacttcc ttcatggcct gaccccgtta ttttcagaaa
     4981 atcccatgcc tctccacccc tcacttctgt taataaaatt ctgtctggat tcatccggta
     5041 attccagcgt ataagcgccg ctggtgttac aacagatcct ttttcatcgg atgactcaga
     5101 aggataaaac agatgaacat agttcttatg tttgtagaat attatctctg ggttgtcttc
     5161 tatcgttgtt atgcgtaaat ggacgggtat atattgtatc aacattttca tgtatgttgt
     5221 tttacccgta ctggtttcac ctgcgacggc taatgttttt ccatactcca cgcatttttc
     5281 cataaacaaa ggaatgtttt ttgagttgta taattcaatc agttcttcgt tatgtgtgga
     5341 tgctttttca atgcctgtga cgcggttata aaaaccgcta tcaatatatg cctgatgcgg
     5401 aatttgaatt tttgacggtt tacggatcgt gattgagatt gtgtcacgtt cgcacgccgg
     5461 aggaacgaca acctgacatc gttctcctga ttccagggtt gcagaaagtc ctggtttgat
     5521 atcctcgata ttatcgttat ggtgttttgc aagacaccga gcaaagttat agcaatcgtc
     5581 aaatttcaga tcaactgtat gttgccccca gacgccatct atctttgtcc agagttcacc
     5641 tggacgatta acagctattt ccgtcaatcc aggaagctcc agaaagtcgc caaagaaacg
     5701 ctgtttatag cggtctaggg aaatattctt agcggtcatc gtttgttcct ttcagcgtga
     5761 ttctggtggt gcactgctgt aaacggccag tgtggttttg cttttaatca gacgctggta
     5821 agcatcctgt gcggcggctt cgttcgggtt cccggcgaga acacccatgt gtccggcggc
     5881 gagcatgtgc aaccaaatct ctttatcttt gcagttcatt tttcatcctc agtgtgtaga
     5941 tatttgagaa gtcaatatcc tgccctgtaa ttaggttgat tatttctccc tgattcttgt
     6001 aaagcgttgg tggaatatta atgctgtttt ccagcgtggt tcgagccata tccgccatag
     6061 cctggcggct gttctctgta tagtctgtat tgcggtcttt tttacccgca ttgtttgatg
     6121 cccatgcgcc aatatctggg atcatgccga ccattaatgc gccgccaaac ctctcccaga
     6181 agtgggtatc aatccatcca tcaacacctg attctccaag ctcgccagcg gcgttggtat
     6241 caatcagcgg aatatccaga tatggtcgct gtcgggtgcg taattttgtc atcatgataa
     6301 aagcgcgccc ctgcccttgc gtaattcctg tctggtatat tcctgttgct gtggttccct
     6361 tctcgataag ttttgtattg ccgctggcac tccagatatc tttagctacc gtacatcgta
     6421 tttttccagc gcgatcggaa acaaagcggt aatccataga acatggaatg actgtgtttt
     6481 ccggtatgta caaatcaggg ttgtagggga ttcttcgcac tgtcgcgggg gaaattgcct
     6541 gtgatgcagt gccatgttgt gttgtggttg ctgtactgtc tgtaggctgt gtggcgttgt
     6601 tttccgcagc cagtatcatt tcctgttgtc ttgtttttac ctgattttgg gggctggccg
     6661 tattattacg acgaacaagg aagctggcct tattcagttg tggtggctca aatgttttca
     6721 tctgtccggc agtaccggat acattgcccg tgttatcttg gctaacagct tgctcaccat
     6781 cagtcgaatt ttccggctca ttggtggcca tgcctaaatc ggttcgtttc cggtagtcat
     6841 tcgttttttt aggtggcgta acctcctttg ttttctctcc atcttcttgt ttcaggaagt
     6901 tttgatatac ccagttaccg ccccatgtca ggccaatcag ggctactgcg catattgcca
     6961 gaaaggccgt tgctttcccc ttctgacgtt ttttcagttt gtttactgct ggttgtaatg
     7021 agttctcctt ttcatcgtcc tgtgatgctt gtaattcagc ctcacgtttt gctctggctt
     7081 ctcgttccag cgtggcgata tcatcctgat cagatgtcgt cactggcttt tcttcttccg
     7141 tagaggggga tttattttcg tcagtcatat atgagtcctt atataaagat ataattatat
     7201 ttttatagat taggtgttat ctgttttttc aacgcgctct accttgttag atacggttga
     7261 attatcagcc gcgtgtacct ttccaaagcc gttatttttc aaccccacta cggcatcacc
     7321 ggaacgtagt acaagccgtg gtgtgatatc ctggataacg agaacggtaa aattgccctt
     7381 acgctgtata ctgctgttaa ctacgtattc ctggccgttc tgttctttgg taactgatgg
     7441 aactgatttg ttgggtgaga atccgataaa cgtaaagcga ccgtcgtcgt aagcaaaatc
     7501 aggttcaatg ctgtaactgt cttttcctgg atatttcgtg tagtcccagt tacgcggggt
     7561 ttgtgcggtt ctcagtgctt tctgaatctg ggcttgttcc tgcttttgtt cccattcttt
     7621 ctgacgtgct gctgcttcct tattggctct gttacgttcg tctcctggat agcggtaact
     7681 cactaggtat gcgggctgtt gtggcgattt ttcatcaatg acattcagtt caacgttgta
     7741 caggcgctta tttgtcacaa tcagcatatt ggtatgccag tcacggctgt tcggcgggat
     7801 aacaacctgt gttgtattac cgtcttcacc tggtgcgccc tgtgtgagcg caacaggacg
     7861 aatgttaacc ctgtttgcat ctgctctggc ttcccatgct tcatcaaagc caggactggc
     7921 actgataaca gcttcatcgt tatcaaaaac cagagtcgtc ataaatcctg gttttgtgtt
     7981 tacaacggta acattctgcg ggttataaat gacctgctgg atacgtgcat cataacggct
     8041 cgcctgtggt gtagctgcgg cccatgcttg gctgttcagc attattatca gggtaattaa
     8101 cgtcagtttt ctcattactc gcctcccctg atttcgcggt cagtctgcca gcttgttacg
     8161 gtgaatccga acgggtttat ttcccgctca acatctgaca tttctttttc agggtctgaa
     8221 tggaaggtga aacgtgcatc ccagtattca ttgcgaatac tgttatcagc catgcgacga
     8281 attatttttt tataacgaac ggtggctact ttgtctggtg ctgttgcatt cgttatctgc
     8341 tcagaaataa tttcaatttt cacggtgtga gccgcgttat tataaacttt gtctggtgcg
     8401 ttttttccgg cgtacagcgc taggtagtcg tcgtttacct gtggtgagtt gtagatctgt
     8461 actgtctcgt aatcgtcctg taatgcagga taaacgtacc gttcacgtaa tttaacgtaa
     8521 ttggcggcca tagctttttg gtaggcttct tccgctgtca gggctgtttt tgatgcacgg
     8581 gtaacgtgtt ccactcgtcc ggtatgatta tctacggtat agagttcaac agttgtttgt
     8641 ttaagtggca acataatcac tatcgcgatc agtgacagga tagcgattaa taaccctgct
     8701 ccaccgacca gaaagcctgc ctttgtggcg cgtttatccc tgtcaatcat ttgctgctca
     8761 aacgagcggg aatcagcaat taatttctgt tcagtcatgt gtggttagct ccgcgataat
     8821 ttggggggtg tttacagggc taccctggcc gctgaatgcg ggcggcaaag gtttagattt
     8881 ttgtgcgcag ccggaaagca cgcacagcaa agccagcgcg attaagcgtt tcattttatg
     8941 taccttttgt tttttctata aaaatataat tatattttta tagttatctt ggagggggta
     9001 aacgtttaat tgatggcggt agttttggtg ttgattgatc tgtcagcatc cgcgcttcat
     9061 tacgcgctat catttgttct atagcgtgtt tacgtgcatc agcagcgtta aatactatgc
     9121 gcgattgtgg atctcctaac cctttattac ttgggcttgc tacttcttta ggtaatactt
     9181 ttcctgcctc ctttaacatc tttccagcgc cgtatgcagc agcgccaatg ccgagagccg
     9241 ccgcaccttg catagtggct gtagcacttg ctcctgcaag tgccccagcc agttttgcgg
     9301 acatgtacac cagtattgca gcgcatactc cggcaagaca aacttgagcg ccaagttcta
     9361 caatattcgc ttgattggct cctgaggatg ctagagcaag ccttgaattt aaatagctta
     9421 ttacaattct taatgataat gaggacagga gaatggttaa tattcccgca aatatatttt
     9481 gcagccagtt attgaacatt ggccgtaaaa agccatacat taggcaaaat ataaatatag
     9541 gtgctgtaat tcctaacaat aagatcataa cctccgcaac catagatacg aatgcagtga
     9601 taatcattaa gacaaataca ccaccccata caaataattc agcaattgtt ccctcatctt
     9661 tgataaattc tgaatcatct aaatcatgta atgttttgcc taataccttg gcgttgtgcc
     9721 ataaagtgtc gagtaactgc cagatacttg aactacttga aaatccttct tttaaaccat
     9781 taacagcatc aataacacca tcaagataac cattaatatt tgccacaaag gataaaataa
     9841 tagccatcct cattatatcc cacatgacat cttccattgg ggtcgacagt ttaccagcta
     9901 aggtttgata tcctctccat atgatgtaga ttgtggctga cgttcccgcc agccccatca
     9961 tcattgaaga ataagacatc attaaacctt gggtagcgtc tgttatgcct cctatcagat
    10021 gtttttcaac accgacaaaa acaccaccag acatttctcc tcctattgat tcaaatcgac
    10081 ggttggcgca tttaattgct gaatttgcca gtgagcctca ttagcatgtt tacagttttc
    10141 tgatgcgcta cctgtttttt ggcatttttc gtaaacagct tttaattcat cggggtgcgt
    10201 tcgataccac tttgttgttt ttgcttcttc ctcgcatcca ttaattaaaa aagctgataa
    10261 agataataga gttattgtta ataaacgcat ttttcatcct taactgttta aatcaagtgt
    10321 tggagcgttt aattgctgct gattccattt cttacggcgt tcctcagcaa gcatcttttc
    10381 acgcttctcc gctgctttta cgttcatttc ccattgggtc gtgagcgtat ttaacatcac
    10441 agattttaac tgaatactgt ttgctaagtc ttgggcctct ttcatatctt tcgcatttgc
    10501 tacacggtct gataattcgt tgatctcacc aagcatctca ccaatctgtg tttgtacttc
    10561 attggtttgt tcgatttgta ttgctttgtt gatgacctct tgtctgcatg tattggcgta
    10621 actttttgat tgttcagcat tgcagttatc gaaaatcttg tatttgttgt acagttcatc
    10681 aaattggcca gaagaaccgc cggataagag caaatcgttc agggcttgcc ctggcttacg
    10741 tagtttatcc aggtcagctt taaggctttt ggcctgatta acgaacgcct gaatgtcacg
    10801 gatgcctgta actgtttcca gttgtttttg atacgcctgt agctggtctt tatagtgttg
    10861 taccgtctgt agccattgat tggcttcttt tgtccactgg cgaatattct ctagtctggc
    10921 tgttgcatca aacacgggta taccagcagc gtttactatc gggctggcaa taagaaccgc
    10981 cagaataagg gggcgaaatc ttttcatcga tatctccttg gttatagtgc tttagctagg
    11041 taggaatcca gccagtcgct gggcttcatt ccctcctgat agagtgattc gaatatttcc
    11101 aggttaggtg cgtcgccgct cattactttt gtgtatctgc cgataccaga cagatccagc
    11161 gtgatacggg ctgcaaagcg ttttgtatct ccacggcgga actgattttt gacaacgaca
    11221 tactgtcgcg cctgtggatc aagtccttta atgacatcaa acacttctgg ttcaaatttc
    11281 attccatcca cgtaatgaga acgatctgcg cttgggttgg cggccagtat ttgagtacca
    11341 cattgctcaa taactgccgg agctatctca tccttgatta tttccgctgg agattgcgtg
    11401 ccaacaacca gcataccgtt cagttttcgt atagttttca gcttgttata cgcaaaatcc
    11461 ttaaatacag ggtcgcgtaa ccacttccag aattcatcca tgaaaataac aagtcgtctg
    11521 ccatccagca ggctggttat ccggtacagc agataaaacg agataggggc gcagacattc
    11581 gggtcatcca gaaattcagt cccgtcaatt ccgaaattat cgcagttgct gatatcgaaa
    11641 gtgtcgtgtt cgttatcaaa cacccaacca aattcaccac cgcgcgccca ctgtgaaaga
    11701 cggatactca ggccattttc ttgcgcttca cgcgttgccg gttccggtag gttctccagc
    11761 attcgggtta tgccgtagac gcgatattga ggctcgtcac tcatgacggc atttacagca
    11821 tcattgaggc gacgttcatc acgtggcgtt atggttgcac cgttgcgggt acaaaggatt
    11881 ttcatcagtt gcttaatgaa attgatgttt cgcttagtgg ctggcagagc aaacggattc
    11941 cagcctgttg gctcaccgct gaataccctg tagtactttc ctccaagtgc gcgaatgttg
    12001 atttcagcac cacggtcttt atcgaggtaa actgtggtta gtcgtttagt cctggcatcc
    12061 ggtgaaaagc tgtcatcacg gttatatttt tgctgattga tttgtaaaaa cgtcatcagc
    12121 attgttttac ctgagccgtt tgtacccaga atgcaggtac ttgcaggatt tttttcgttg
    12181 aactcgtctt tatctgccag agtgttatgc agattcagat agtagccatc acctgacggg
    12241 gttcgcacca gagccatcgc gtcaccccac ggggctttgt cgcgttttcc tggatagaaa
    12301 ttatgaagtg atgccagttc aacaaagttc aggctactca gctctccagc tcgtggccgc
    12361 agattgtaat tgcctggtaa ttgagccata taggccgcag acaatgagat ttcagcagga
    12421 acaggggtta tcccgatatt gttaagtgca ttgctgatct cgtttgtgtc tgcaaccagg
    12481 ctttccagtg acggcgaaaa caccataatt gataaatgat gtttaccgta ggcgatttta
    12541 ccggaggtaa gtaggtcaag cgccacatcg agatccagac gttgagatac agcatcatca
    12601 tcagcactca tcatcagccg tcgggtgcgc ttaatcgcct tttttgcttc ctcacgggac
    12661 atgcaggtat aggattgtgt aatcacataa tcgcacggcg cgtacagtaa ggagtctgtc
    12721 atgcccgttg cggtttcttc cgaaaactct ttaacctcca gaccacggaa atattgagtg
    12781 ccattaacat gatttatttg ccctgattcg gcggagaagt acagcgcaac atttcccatt
    12841 acgttgtaag cgggagtacg tgtaactctg acttttcgcc attgatgcgt gataaggtat
    12901 tcataaaatg ccagttgaga cgagaataca gcctcgtttt cggtaaaagt accgagcgcg
    12961 tgagcaccat aacgggataa ggctgtatcc agcgtacttt tgatttccag cacttcaagt
    13021 aatgcgctgt ctatctcttt tagcttctga ccgtctttca tacgtttacg gtttgcctta
    13081 tccagactgg caaacggacg atagcagatg gtcacaaaca ggcggttacg tcggaatggc
    13141 cttttattca gtgatgcgta atagcgttcg ctcacggtat ccgcgtaagg gtttcctgaa
    13201 accttatgca gtgagtccgt aaactgttca cggctgttat gtacataaaa tgtaaccgga
    13261 aagccttcaa atgagcgtat tagcccgtgc aactggtttg taccgaactg tagtgtctcg
    13321 tcagattcac aatcaaacgg cgttcctgtc agttcccagg tacagaaaaa atcgctattc
    13381 agtgaacgga caacattagg gtgaatatgt gacgagtaag gaatgtattt ttttatggtg
    13441 gcacattggt ttagcttcat cgcatcgata aactcctgga tatcaacagc attatgttca
    13501 acaggcataa atgcggttgc gccaaataaa cggtttgcta ccggattacc ccttaccctt
    13561 agccagacag ctatcaggtt aaatctcaga ggttcatttc tggttagtga tttcataacc
    13621 agaaactcaa tagggaggaa gagaagtagg gctatggaag tccagatagc aacaataatt
    13681 gtcacgccca cgacagtcag caggggcacc attggcaccc cccacagcgc cgccggacgt
    13741 ttcatcgcct taagcagctt tgccatatgt tcggcctctt agctcattag cagagcgcca
    13801 atttcactgc ctccgccaat taaaatgccg ccaatgatga tgtaaccgca ctgcgacagg
    13861 ctttcgcctt tccacagagt cttatagcca atccagatta cagcgacggt gatggtgacg
    13921 gctgccagac catgcagacc attcgaaacc ttttccatga ttgtatttgc tcggctaaaa
    13981 ccgtcagccg cgaaaactgg actgacaaca cttactaacg gagccagaat ataagcagat
    14041 gcgcggctgc aaatggtctt taatttgtta aacatcggtt aatcctcttt ttcagttgaa
    14101 aatctgtttc cgcgtataac ttgtgcgggg taataaacgg tatctgcctt tttctggcgc
    14161 agttgagcag gaaccccgcg cacgattgcg ccaggccaga caacgcgagg gcgtgccgga
    14221 gcttcaacgg gtgttgcatt cagaatggct gattgagttg cgatatcatc cttggttcca
    14281 ggaacgacat agcggggctt ttcaggtgag taaccaattc gctgtatgta actggttctg
    14341 gataacgctg cttctggttg ttgtcctgta gtaaaatttc cagagtaata acaactcagc
    14401 gcccgtttca gtgtgccgcc tcgctggtag caatcagtga tgatcttttc aaaaacagaa
    14461 agatttgtgc acgggttgaa caggtcagca gccgttacgg cgtaactatt aaaatttgta
    14521 cttgtgattt gcatcagacc aacagaatag cgacgacctt ttgcctctat ctgtttgacg
    14581 atgcttaatg catcctcctt agtttttggc atatgtgaga taaagccctt gtcgcctggc
    14641 tggcgttcac gtttggggat gatctcagca atagcgtagg gattaaaacc agactcgacc
    14701 cgcgcaacat ccagtgatgt ggaggggtga actgtggcgg cacactgcat agccaccgcc
    14761 ataaatgaaa cggtggaaag catagtaccc tcgctaaatt agtttccttg tggggcgtct
    14821 tctttaggtt cgagtagtac cagcttgccg gaaacagcaa taccaggaac gagcataata
    14881 ttcagtcctg gtttttcgtt atgcgcgaat gccgcgccaa ccttggtcca gtaggtattt
    14941 ttaccgccgt tttcgtcagt gggaacttcc tgtgtgacgt atacgttata ggtgggtttg
    15001 ggcatttatt tatcctcttt tgacattagc tctttcaaca tttcgttgtg agcttcatta
    15061 cttaatttgt cgatcatgta ctgcaaaaag gcacttggac gaatatttac ctccgcaaca
    15121 taacttatat ctctggcgtg ttttgccagt gtttcatagc gttttttgcc gatgtaaata
    15181 acggctgtag atttagcctg gcctataggg ttcggcatga gtttatagct cctgtatgaa
    15241 atatccgtgt gcaaaagcac agcggtacga ctggagaagg aatgaaggtc tggtttactg
    15301 attctgtaaa agcctggaga aggccgtttg acgttctaac ggtgagatga ttgaagatat
    15361 gcgttgaatt tctgccagta ggtcactacc gatgttacgg cactctatag aatcatcatc
    15421 aggatttagc gccagtatct tggcgcattt aatagcgata acgacttttt ccggtacagt
    15481 acatattgtg gaaccgaaac ttacgaagcc aattgcacct ggaatagagg ttattgctga
    15541 cgtgtgcgtg acattcacat caaaatggag gaagaggtag ttaggaaata aaactttttc
    15601 ttccttacgc actgcgttgc aatctttccg aggtgtgaac tttatgtatc tcggacagaa
    15661 agccacaacg ttcatagttt tacaacgata tgcaatacga tctaaatcgt tgttattaca
    15721 gtataaaaga taccatgcat tcataagcgt caccttacgg acacaagccc ccattttccg
    15781 ccgtcctaag ttgccgggct taggctgacg tactcattaa gtgttaactg taaaaatata
    15841 cagttgtgat cttatacagc aattcttgcg tgtcaatatc aagaatctaa agaaataata
    15901 acaagaatgt tcattaagtc aaaacctttg aatgtatgaa cattcggggg ttggtgccga
    15961 tgtatgtttt ggaaaacaaa acaaggggat aggtcaatgg tgccaaaacg attgaaagaa
    16021 gcgcgggaag ctgctggttt atctcaggaa aagctatcag agttagtggg gatagaaggg
    16081 actagcacaa gatctaggat gtctaattat gaagcgggac ggtttacgcc accatttaaa
    16141 tttatctgtc gagtggcaga tgtcttagga tatccagaat attatttcta tatagtgaat
    16201 gatgtaactg ctaaaaagtt acttcagatg tacaagggag aaaaaaacag cattgaaaac
    16261 attgagttgg aggcaagtag aatggctgat caacttgatg atgctagaaa attagtatcc
    16321 caacttagcg actgtgtgag agagcttaaa cgttcgttag ggtaagtttc gggcatcagt
    16381 gcgtatgtgc tccatttggt caagtcgctt ttccgcttcc tcacccactc gctcactaac
    16441 gttcggtcgc tggggctgcg gcgagcggta aatactctta catattttta tcaaaatcct
    16501 ttatttttcc gtttgttgtc gccgattttt tttcgatatt aatgctaatg tatgcgtaca
    16561 ttagcattaa tatcatgagt tatgtgctgt acggtattta atctcaattt tgttaagagt
    16621 tatataacca gatgaagtgt aaagaaaaat agtaaggtaa tcggcgggat cttttgtgga
    16681 tgaattgatc ttcgaatggg ttcatgctat tttcgtgcgg tttttacgga tttttgggtg
    16741 ggacgttccc gtaacagcgt ccaagggaag ggggggaagc attttagccc ccctgaatgc
    16801 aacaaccccc tgatatctct cttcgatttt gccggtccaa gaagataatc agggggtcca
    16861 aagcaggctg ggtgcctgca aaggattata gcaaatgcat ttctcaatac aagacctctg
    16921 tccggcaata agtgcgggcg gtggtggctg aaaagaacaa ctccttaatc ccccgcatat
    16981 cgccgtcagg tgtggcaaaa caaagtccat gctataacgt tgtgtcgcgt aagcgacgcc
    17041 gttttctcaa tcgctggatt aaatcgctga cgacggtcgc agggcgtatc aaaatcaaaa
    17101 acgaactccg tcgccgtatc cggcataacc gctattgggt taatgaggct aacaagtttg
    17161 gcatagaggc tctttgcgaa ttgatgttag ctattctgga cgatctcgat ttacgctcgt
    17221 gggaaaccag gcataacctt gaaacgcttg ccgaacgtgc cggactggtt acacgcagcg
    17281 atgcgggaca taaatccatt tctcgcgcca gtcgtggttg tgatcgcctg gtttggttga
    17341 atgccatcat tacagagaag gctccgttta acccgtatga tgcacggtgt gcctgtaaac
    17401 acattgaagt aaccgaggat ttctttgcca tccttggcat tccgttaaaa ctggtttatc
    17461 gggaacgagc caggctgtta aaggcagatc ctgatgaagt gatttactcc ggtgatgcca
    17521 gacttatagc tatcagagtc cagaactgga cgcggaaagc ggcagccgga ttagccagga
    17581 tgaaagcaaa acgcgacgca gctcgacaac gcaaaaaaga atattacgca cattcaccta
    17641 cccccattcc ggcctgatgc tggctactta ccgccttatg ggcggtatat cgtcacgtcc
    17701 ataataaatt tctgtacaaa aaatagtctt agcgtgagat attttcgttt tccaagcggc
    17761 tccctgctca ggaaagagca gccataggtt atggccagag ggtaaacgat gtacagcttg
    17821 tggataatca taagtgaagt gcaaacgata tgacgcaatt actcttttgc ttctctttta
    17881 gttacttacg tactaaaaga gaagcaaaaa gaaaaacatt actgttatcc cctttaacaa
    17941 gtggataact gaaaagcatc ggcgcaagcg cctcaaaggt agcacccctc gcaagcatcg
    18001 gggcattaga gacaccatat ccgatcatta aaaacgaaca atcattcacc tatcatcgct
    18061 gtaacatcga cggtctacga ccacctaccg cctaagtagc tgtaggttcc gtgcaatttt
    18121 ggcttagcag ggggctgacg cggttcctgg cgacatgaac gtctttgatt aggggtatcg
    18181 gcgcgcctta gcatttgtga ttctatggaa ctgtatttcg cgccttacat gccgctaacg
    18241 cggcatcttc ccaccatcga gcataactta actaactgct aacaatatga tcgagaaaga
    18301 tcacaaaaag gttcctgttg ggggtctgtt tggaaatcgg aaatttcggc gtttccggtg
    18361 tacaacccta gggaggtaga tccgctcgcc gcagccccag cgaccgaacg tagtgagcga
    18421 gtgggcgagg aagcggaata gtgcccttgc tgaattgagc acatacgcga aggaattaaa
    18481 ggtgagtggt ggaaaatttt tcagttcgaa tagtgaaaaa tagttgcaat acctgcatac
    18541 gcaggtataa taaaatcatc gaaagggaaa taggttccct ttccacttag ccccacaggg
    18601 gcgggagatt aaaatgagtg catttatttt tagaaccaca tttaaagcaa ctggcgatca
    18661 gcaaaaagac gctattaccc aaattgaagt tatgcaggaa caagcagtaa aagcctttgt
    18721 ttcttggatg accaaccagg agggtacaaa atttttaagc actttgcagg aaatcacaac
    18781 agaacttgac gcactgattg atgcggtaga gtcccattcc cctgttttca gaaagaaagc
    18841 gactgaactg gaagcgcttt tagcccatta caaaacgttg ctgtaagtcc tcaacggggc
    18901 aattgccccg ttatatggct ctttatttaa tccaaatcta aagcaagtgg agtttaaaaa
    18961 tggctcgctt accttatatt gaatcaacca cgcaacagat ttttattttt aatactttga
    19021 cactttgtac tattggatta attcatatag agactggtaa aaaatatatt gtagtattta
    19081 cagataacaa taagattcga gattataaaa atggtgtaat agaagaatta ggggaaatta
    19141 tgcaagaaga tattgaactg attgagtatt atgctaaaaa atatgaaaag tattttgata
    19201 atttaaaaat aggtgaggag cctttgaatc ttaaagaata tatagaatgt atgcaatagc
    19261 catatattct ataaaggtgt gatcaggttg gtcgagcaac ctgatcactc tatcgacact
    19321 caaaacaata gagaggtgtt caaatgtcaa caggtcagat cgtacaactt gcggattcac
    19381 ttgtcaaagg atgggaaacg agaatcccag caatgaaatt tacggattgg gatcaattca
    19441 ggtggtggtt aaattattta cagggatatg aaatgtttta agtaatgttg atgtcctgac
    19501 agtaattata aaatttttca aaaagagagc taaaaaactt gcaatacctg caattgaagg
    19561 tataattaaa ccatcgagag ggaaatggtt tccctctcat cttagcccca caggggcggg
    19621 agttacaaaa tgaatatcca agaagcatta aatatttttg gcttgtctgg tcagttgact
    19681 gaaaaagaca tcaaagatgc ctttaagaaa gctgcattaa aatatcaccc agaccgtaat
    19741 ccagtaggtg ctgaaatgat gaaggcggct aattcagcat tcgatttttt aatggcgaat
    19801 cttgataaga ttaatcagta ccaaagtcct gaacaaagtg caatatataa ctatggtgat
    19861 gaactagaaa atgttttaaa ggctctttac ggtttgtctg gtttagttta tgaggttatt
    19921 ggtaactgga tctggattag tggaaatact atcgagcaca aagaagcatt aaaagaaata
    19981 gggtgtaaat gggcggcaaa gaaaaaacaa tggttttatc gtccagaaga atataaaagt
    20041 tactggaacc gtgaagagca cacgatagag gaaatccgcg caaaatatgg cacaagcgga
    20101 aaattccagg ccggaggatg gcaacaagtt gaaggcaggg caagagttga agccagagca
    20161 taacgaaacg ggggcgtaag ccccctatat cctcgccagc aatccttttc gggcatcgaa
    20221 cccgaaaagg attgagtagc tgacactctg cgattgctgg ctacgttagc gcagtaaagg
    20281 atgtgaaagc atgacaacat tttcagaaaa atatcagcct gtctttgaag ttgtatgccg
    20341 tattcttggg aacggctggc gtgttaacaa actggataat tatcagcatc gtattaaact
    20401 gacttctaca gaatttcgta aatactccat cattattcgt ctggagcgtg aaagattttt
    20461 tatagttggt agcgttgata gtcttgtatg gcacggtaat ccttccgtct gtactgtatc
    20521 tcttacgcgc aatcctgttg gtattgctaa tgatatatct cggaaaatcc ttgctaatgc
    20581 accggatgaa attgaattgc tcagggggca tgagagcgca ttacaggaaa aacaagataa
    20641 agtgcgaata atcaaaggga tgttatcaca gttgctttct atatctccct ggtatggggc
    20701 attaacggga tttaatgcgg ataatggact tgcaggaaaa atactacaaa atggtgatga
    20761 ttatgaaatg gttatcagag ggcttaatgt tgagcaactt atcaaagtgg caggttttat
    20821 aaaaaaacta taacaaagtg ttgatgtgaa tttttatatg ggattgttta tgaaaactga
    20881 taatgttttc tttaaaagta agggtagtta ctcttatgtt attacagtag atatggataa
    20941 tcaggtgtat atggtcagaa agtatgttaa gacatatgtg aaatcttgtg ataaagagca
    21001 agttaaaggg aaaaagacag ttaaaaaatt ggtgcttgat acgaatctta cattgccaga
    21061 attattgagt cttgataatg gtattctggc tgatttattt acaagaggta ataacaatgc
    21121 aaactaaacc aactccggca gatgttaaag aagcgagagt ttccgcaggt ttaacgctta
    21181 aggaagccgc cgaaattttc ggctatcagt taaatacctg gcaaatgaaa gaaagcgcag
    21241 gtaaagctac aaggtcttta tcagtaggtg aatataacta cttattgttg ttggctggaa
    21301 aacaccctga atatgttctt tgtaaaaggg atacagtggg tattttaaat aattaaggat
    21361 aatacaatta attcgccgaa aatgaacttt tcgcccattt tcggctttca ctcctaaaaa
    21421 gctgcaatta ttcacgcatc atttgcagtc ctgtttccag aatcatctca ttagccatgg
    21481 ctttggtgac ggaattttct gggtttccgg tttagaaccc ccttaggaaa tttttcggca
    21541 ctgttgcaaa gttagcgatg aggcagcctt ttgtcttatt caaaggcctt acatttcaaa
    21601 aactctgctt accaggcgca tttcgcccag gggatcacca taataaaatg ctgaggcctg
    21661 gcctttgcgt agtgcacgca tcacctcaat acctttgatg gtggcgtaag ccgtcttcat
    21721 ggatttaaat cccagcgtgg cgttgattat ccgtttcagt ttgccatgat cgcattcaat
    21781 cacgttgttc cggtacttaa tctgtcggtg ttcaacgtca gacgggcacc ggccttcgcg
    21841 tttgagcaga gcaagcgcgc gaccataggc gggcgcttta tccgtgttga tgaatcgtgg
    21901 gatctgccac ttcttcacgt tgttgaggat tttacccaga aaccggtatg cagctttgct
    21961 gttacgacgg gaggagagat aaaaatcgac agtgcggccc cggctgtcga cggcccggta
    22021 cagatacgcc cagcggccat tgaccttcac gtaggtttca tccatgtgcc acgggcaaag
    22081 atcggaaggg ttacgccagt accagcgcag ccgtttttcc atttcaggcg cataacgctg
    22141 aacccagcgg taaatcgtgg agtgatcgac attcactccg cgttcagcca gcatctcctg
    22201 cagctcacgg taactgatgc cgtatttgca gtaccagcgt acggcccaca gaatgatgtc
    22261 acgctgaaaa tgccggcctt tgaatgggtt catgtgcagc tccatcagca aaaggggatg
    22321 ataagtttat caccaccgac tatttgcaac agtgccaaaa aaagttggta atgggataaa
    22381 taaaaaagaa aaaaccaaat tcaaaaatta tatggagatc tgtataataa agaataatta
    22441 ttaatctgta gacaaattgt gaaaggatga aagaaatgaa ttttaataat aaaacaaagt
    22501 atggtaaaat acaggaattt ttaagaagta ataatgagcc tgattataga ataaaacaaa
    22561 taaccaatgc gatttttaaa caaagaatta gtcgatttga ggatatgaag gttcttccaa
    22621 aattacttag ggaggattta ataaataatt ttggagaaac agttttgaat atcaagctct
    22681 tagcagagca aaattcagag caagttacga aagtgctttt tgaagtatca aagaatgaga
    22741 gagtagaaac ggtaaacatg aagtataaag caggttggga gtcattttgt atatcatcac
    22801 aatgcggatg taattttggg tgtaaatttt gtgctacagg cgacattgga ttgaaaaaaa
    22861 acctaactgt agatgagata acagatcaag ttttatactt ccatttatta ggtcatcaaa
    22921 ttgatagcat ttcttttatg ggaatgggtg aagctctagc caaccgtaaa gtatttgatg
    22981 ctcttgattc gtttacggat cctaatttat ttgcattaag tcctcgtaga ctttctatat
    23041 caacgattgg tattatacct agtatcaaaa aaataaccca ggaatatcct caagtaaatc
    23101 ttacattttc attacactca ccttatagtg aggaacgcag caaattgatg ccaataaatg
    23161 atagataccc aatagatgag gtaatgaata tactcgatga acatataaga ttaacttcaa
    23221 ggaaagtata tatagcttat atcatgttgc ctggtgtaaa tgattctctt gagcatgcaa
    23281 acgaagttgt tagccttctt aaaagtcgct ataaatcagg gaagttatat catgtaaatt
    23341 tgatacgata caatcctaca ataagtgcac ctgagatgta tggagaagca aacgaagggc
    23401 aggtagaagc cttttacaaa gttttgaagt ctgctggtat ccatgtcaca attagaagtc
    23461 aatttgggat tgatattgac gctgcttgtg gtcaattata tggtaattat caaaatagcc
    23521 aatagtattg aacaaggtat atagctgata taataagggg cactgttgca aagttagcga
    23581 tgaggcagcc ttttgtctta ttcaaaggcc ttacatttca aaaactctgc ttaccaggcg
    23641 catttcgccc aggggatcac cataataaaa tgctgaggcc tggcctttgc gtagtgcacg
    23701 catcacctca atacctttga tggtggcgta agccgtcttc atggatttaa atcccagcgt
    23761 ggcgttgatt atccgtttca gtttgccatg atcgcattca atcacgttgt tccggtactt
    23821 aatctgtcgg tgttcaacgt cagacgggca ccggccttcg cgtttgagca gagcaagcgc
    23881 gcgaccatag gcgggcgctt tatccgtgtt gatgaatcgt gggatctgcc acttcttcac
    23941 gttgttgagg attttaccca gaaaccggta tgcagctttg ctgttacgac gggaggagag
    24001 ataaaaatcg acagtgcggc cccggctgtc gacggcccgg tacagatacg cccagcggcc
    24061 attgaccttc acgtaggttt catccatgtg ccacgggcaa agatcggaag ggttacgcca
    24121 gtaccagcgc agccgttttt ccatttcagg cgcataacgc tgaacccagc ggtaaatcgt
    24181 ggagtgatcg acattcactc cgcgttcagc cagcatctcc tgcagctcac ggtaactgat
    24241 gccgtatttg cagtaccagc gtacggccca cagaatgatg tcacgctgaa aatgccggcc
    24301 tttgaatggg ttcatgtgca gctccatcag caaaagggga tgataagttt atcaccaccg
    24361 actatttgca acagtgccaa tttttcccac ctgtaaagca ctttttatat aaatctataa
    24421 ttatataaaa ataatcgatg tttttttgaa cgctttttac taaacatatt tgtttagtgc
    24481 atcatggtgt attttataga tcttgaaaag acaatgacag tagtgatagc atctaagaca
    24541 gccgagacgt acagcccaac aacttaataa aatataaaca catgagggtc ataatatggc
    24601 aaagccaaaa tctgaaattg atgctattcg agcattaaca gaagtaacaa taaaaggttt
    24661 tgagcagatt gttcaggcat tagatgatac gagagaagct cagggaaaag tcgcacgagc
    24721 aacatataat ggattaacct cctcaggaaa atctcgctat gttgcatcgc tagtgaagga
    24781 agtaggatca caagctgaag taagccgcat gttaaatatc acaccagggc gcgttagcca
    24841 gcttatgaaa tccgaaaaaa accgcaagaa tggtaagtaa ataagtaagg ccccaatggg
    24901 gccttacatt atgctagaca tggaacgcta ctcgctttcc tgtaggaagc tcaacatcca
    24961 ggcttaattt gcctcccata gcttcaacgt aacgctttaa tgtcgccagc tttaaatcat
    25021 ttccgcgctg ctccagcttt gttactgctg gctgactaat acccatcgcc tcagcaacct
    25081 gtttttgtga taactggagt tcttcacgca tcatctgcaa gccgacctca agaatcatct
    25141 catctgccat ttctttaatt cgcgcctggc tttccggtga acggctggca atcacctctt
    25201 ctaatgttct cattacttgc tctccagtgt gttcagatgt gctgcaaact catcctcagc
    25261 tatacgcacc agttttttat aaaaccgctt atcgttactt ttgtctcctg cacaaagaac
    25321 gatagcccgg cgaatcggat cgaacgcata aaaggctctt atcggacggc cagaaaactg
    25381 aacgcgaagc tctttcatat ttttgtaccg agaacctttt acggtatcgg catatggcct
    25441 gggtaactca ggtccgtaaa cctgtagatt tttcaaatca gccaaaacct tttcctgaag
    25501 agcgtcttct tgctcattta gccagtcgtc aaatcgctgg ctaaaaagta ccgtccacat
    25561 gatcaatcct ataacctgta gtttatatca ctaactatat aacccgtagg ttataatttc
    25621 aagaaaaacg gggctattta acataatgga cgttatcggc accatcggat caccgttcgt
    25681 tgtcggatct gcaaaatccg ctcaaaagat catgttttct tggcgttttc caccgttttt
    25741 tgtgttgcgc atttgttaat aaaacatcgt tttttgtttt ggctgaattt tgttgtgaaa
    25801 gccttgtatt cacaagttat ctcttcactt gccgcctgta gttcaaatag ttgttgcaat
    25861 tcttggcacc aatacggata ctataattat atttttctat aaaaatattt ttataggggg
    25921 tcgtatgacg gtagctattg cgctggttaa cggtaaaggc ggggtgaaaa agtcctcaat
    25981 gagcagggct attgccacag agtacacaaa ggcagactgg aaggtattag ggcttgatat
    26041 ggatgttgat caggggtcat tcctggattg gggacagcgg cgattgagat ataaagttga
    26101 accacctgtc actattcagg gatgcggaac ggtatcacag gctaaaaaac atattgaatc
    26161 agggatatgg gatttagtcg ttatcgatag tgctgcttat gcaactaaat cgctgttgag
    26221 cctggcagaa attgttgatt tgctcgtgtt accgtcaggt tttagtgtgg acgatttgag
    26281 aacgacggtt acaaccgtga atgcattgcg taacaaggga tactcaacaa ataagatggc
    26341 tgtagttttt gtcggagtca gtgaaagcga aagtgagtat cgtaccgcgc ttgaatatct
    26401 taaaccgtgt ggtgtccagg ttatcaatgg cgcaatacct tttatgacct cgttcagcca
    26461 ggcacaggat aaaggactgg cattgacgga atcccctttt ccaggtccac ggcagaaagc
    26521 tgatgaagtt gtccagggag ttattgactt gctgactaaa ctctcacagt gatatataat
    26581 tctataatta tatttttata gaggtgataa gatggctaat gtaccaccaa aaccgcgtaa
    26641 caccaaaggc gagccgccaa gtctggagga tacacaatac ggatttaatc cgacgcgtaa
    26701 aaacgctgat gggagaaaag ctcagcttaa cctttatgtg gatatggaag ttaaacggga
    26761 gttccgctcg attgcagcgg ctaatgatat gaagcacggg gagttgctgg aggcatacca
    26821 ggaattctgg aaaaagcatc attaaaatgt cataggggac gaactgtccc ctgatattaa
    26881 cacttactta ccaacataat gaatatggtc aatacgacaa gtatttttat cgtcatcatc
    26941 gtctccatta tcatattctg gaaacactat tagtaacgct tcgccgttgg tgcgtttcat
    27001 aaaattgaac actaatctgc ctacttcttc atttgtcata tagcgttcta ttggcaatgt
    27061 ttcgtattga tccgcataga gaatattcac actttcttct tctggttctg aaatctggcc
    27121 aattgtgata tctgtcagac ctgtatcagt gaaatttcct gattttatgt caaagtcgcc
    27181 atctttgaat ttgtatgcat cctgccatac agcgaaacaa gtgtggcagg tgatgggcag
    27241 ttcgccttca gccagctttt cacaattttg aaccagtact cgctcttggt tgtactgtaa
    27301 gttatagcca cctgtacaaa gcgtttcata cccatgagcg ccagttacga tatgtgtcgc
    27361 aaccctttcc aagactttcc cattcactaa taactgttca cgtgtggtaa ttgtttgcat
    27421 gtcaatctcc tatttatgtc gccattccca cggtggaacg ggattggggt cagcccataa
    27481 acctcgtttt tgtgagcgag cttcctgttg tagagttgct agatcgttat ctgtgttgta
    27541 acgctcatac acccatgcag cacccgattg caccataaag cggttagcct cactgccgcc
    27601 tgttgtgaat acacgtccga taatgcgacc gtaacggtca ttgtgtgaat atgtcaccct
    27661 gacggattgt ccggcaatca ggcttttaag ctggtcagtt gaccagcgtc cgtaagcctg
    27721 tttcttttcc ggtgcatcaa ta
//
