LOCUS       NZ_CP139954            24403 bp    DNA     circular CON 26-JAN-2024
DEFINITION  Escherichia coli strain Nord1 plasmid pNORD1_2, complete sequence.
ACCESSION   NZ_CP139954
VERSION     NZ_CP139954.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38610602
            Assembly: GCF_034424275.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24403)
  AUTHORS   Braun,S.D.
  TITLE     DRESI Project
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24403)
  AUTHORS   Braun,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2023) Optical Molecular Diagnostics and System
            Technology, Leibniz Institute of Photonic Technology, Albert
            Einstein Strasse 9, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-SEP-2020
            Assembly Method                   :: Flye v. 2.8.1-b1684
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 199.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 12:30:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,403
            CDSs (total)                      :: 5,279
            Genes (coding)                    :: 5,040
            CDSs (with protein)               :: 5,040
            Genes (RNA)                       :: 124
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 239
            CDSs (without protein)            :: 239
            Pseudo Genes (ambiguous residues) :: 0 of 239
            Pseudo Genes (frameshifted)       :: 119 of 239
            Pseudo Genes (incomplete)         :: 133 of 239
            Pseudo Genes (internal stop)      :: 43 of 239
            Pseudo Genes (multiple problems)  :: 54 of 239
            Pseudo Genes (short protein)      :: 3 of 239
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP139954.1.
            Bacteria and source DNA available from Leibniz-IPHT Jena.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24403
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Nord1"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pNORD1_2"
                     /geo_loc_name="Germany"
                     /collection_date="2020-05-12"
     gene            complement(join(24230..24403,1..30))
                     /locus_tag="U0533_RS26425"
                     /old_locus_tag="U0533_26425"
     CDS             complement(join(24230..24403,1..30))
                     /locus_tag="U0533_RS26425"
                     /old_locus_tag="U0533_26425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_327058925.1"
                     /translation="MPNPIGQAKSIYIGKKRYETLAKHARDISYVAEVNIRPSAFLQYM
                     IDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            complement(107..556)
                     /locus_tag="U0533_RS26430"
                     /old_locus_tag="U0533_26430"
     CDS             complement(107..556)
                     /locus_tag="U0533_RS26430"
                     /old_locus_tag="U0533_26430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998906.1"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_000995159.1"
                     /translation="MNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIKITPRKDCNAV
                     RKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKVVIAIKCAKIL
                     ALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            811..1176
                     /locus_tag="U0533_RS26435"
                     /old_locus_tag="U0533_26435"
     CDS             811..1176
                     /locus_tag="U0533_RS26435"
                     /old_locus_tag="U0533_26435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000248966.1"
                     /translation="MVPKRLKEARMEAGLSQEKLSQLLGVAEGINTRSRFSSYEVGRTE
                     PPFKLVKKIAELLDYPENYFYTEDDDFAKAVLDFHRKRTSPELNPNYDSEVEARRMASK
                     LDNVKKIVAQLNEYLKE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            1823..2458
                     /locus_tag="U0533_RS26440"
                     /old_locus_tag="U0533_26440"
     CDS             1823..2458
                     /locus_tag="U0533_RS26440"
                     /old_locus_tag="U0533_26440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371526.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_000088100.1"
                     /translation="MSRKRRRFLNRWIKSLTTVAGRIKIKNELRRRIRHNRYWVNEANK
                     FGIEALCELMLAILDDLDLRSWETRHNLETLAERAGLVTRSDAGHKSISRASRGCDRLV
                     WLNAIITEKAPFNPYDARCACKHIEVTEDFFAILGIPLKLVYRERARLLKADPDEVIYS
                     GDARLIAIRVQNWTRKAAAGLARMKAKRDAARQRKKEYYAHSPTPIPA"
                     /name="RepA family replication protein"
     gene            3415..3687
                     /locus_tag="U0533_RS26445"
                     /old_locus_tag="U0533_26445"
     CDS             3415..3687
                     /locus_tag="U0533_RS26445"
                     /old_locus_tag="U0533_26445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001272119.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTNQEGT
                     EFLSTLQEITTELDALIDAVESHSPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            3761..4060
                     /locus_tag="U0533_RS26450"
                     /old_locus_tag="U0533_26450"
     CDS             3761..4060
                     /locus_tag="U0533_RS26450"
                     /old_locus_tag="U0533_26450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000113288.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGEKYIVVFTDNNK
                     IRDYKNGVIEELGEITQEDIELIEYYAKKYEKYFDDLKIGEEPLNLKEYIECMQ"
                     /name="hypothetical protein"
     gene            4431..4964
                     /locus_tag="U0533_RS26455"
                     /old_locus_tag="U0533_26455"
     CDS             4431..4964
                     /locus_tag="U0533_RS26455"
                     /old_locus_tag="U0533_26455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_021533589.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKNAFKKAALKYHPDRNPVGAEMMK
                     AVNSAFDFLMANLDKINHYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="J domain-containing protein"
     gene            5092..5634
                     /locus_tag="U0533_RS26460"
                     /old_locus_tag="U0533_26460"
     CDS             5092..5634
                     /locus_tag="U0533_RS26460"
                     /old_locus_tag="U0533_26460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000206647.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTEIRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANALDEIELL
                     REHESALQEKQDKVRIIKGMLSQLLSISPWYGALTGFNADNGLAGKILQNGDDYEMVIR
                     GLNVDQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            5670..5927
                     /locus_tag="U0533_RS26465"
                     /old_locus_tag="U0533_26465"
     CDS             5670..5927
                     /locus_tag="U0533_RS26465"
                     /old_locus_tag="U0533_26465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000845367.1"
                     /translation="MKTDNVFFKSKGSYSYVVTVDMDNQMYMVRKYVKTYVKSCDKEQV
                     KGKKTVKKLVLDTNLTLPELLDLDNGILADLFTRGNNNAN"
                     /name="hypothetical protein"
     gene            5917..6162
                     /locus_tag="U0533_RS26470"
                     /old_locus_tag="U0533_26470"
     CDS             5917..6162
                     /locus_tag="U0533_RS26470"
                     /old_locus_tag="U0533_26470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001193619.1"
                     /translation="MQTKPTPADVKEARISAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTITAEPTTV"
                     /name="hypothetical protein"
     gene            complement(6193..6492)
                     /locus_tag="U0533_RS26475"
                     /old_locus_tag="U0533_26475"
     CDS             complement(6193..6492)
                     /locus_tag="U0533_RS26475"
                     /old_locus_tag="U0533_26475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001259443.1"
                     /translation="MRTLEEVIAAQSPESQAIIKAMADEMILETGLQMMREELQLSQKQ
                     VADAMGISQPAVTQLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFNI"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(6489..6839)
                     /locus_tag="U0533_RS26480"
                     /old_locus_tag="U0533_26480"
     CDS             complement(6489..6839)
                     /locus_tag="U0533_RS26480"
                     /old_locus_tag="U0533_26480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269926.1"
                     /translation="MWTVYFGRLFDEWFEEQELALKRKVLAELKHLEEFGPSLSRPHAD
                     TVKGSRHKNMKELRIQYEGHPIRAFFAFDPIRQAIILCAGDKSNDKKFYDRMIRIADEE
                     FSTHLAELEGKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            7205..7852
                     /locus_tag="U0533_RS26485"
                     /old_locus_tag="U0533_26485"
     CDS             7205..7852
                     /locus_tag="U0533_RS26485"
                     /old_locus_tag="U0533_26485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000214917.1"
                     /translation="MTVAIALVNGKGGVKKSSMSRAIATEYTKADWKVLGLDMDVDQGS
                     FLDWGQRRLRYKVEPPVTIQGCGTVSQAKKHIESGIWDLVVIDSAAYATKSLLSLAEIV
                     DLLVLPSGFSVDDLRTTVTTVNALRNKGHSTNKMAVVFVGVSESESEYRTALEYLKPCG
                     VQVINGAIPFMTSFSQAQDKGLALTESPFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     gene            7892..8125
                     /locus_tag="U0533_RS26490"
                     /old_locus_tag="U0533_26490"
     CDS             7892..8125
                     /locus_tag="U0533_RS26490"
                     /old_locus_tag="U0533_26490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000024515.1"
                     /translation="MANVPPKPRNTKGEPPSLEDTQHGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(8157..8420)
                     /locus_tag="U0533_RS26495"
                     /old_locus_tag="U0533_26495"
     CDS             complement(8157..8420)
                     /locus_tag="U0533_RS26495"
                     /old_locus_tag="U0533_26495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="WP_001312455.1"
                     /translation="MTIKILVVSNDGHEKLIDLSPDNDLAKITKSLRTAENRMVCVIQD
                     NNRILRWDRSYASRAKNHWRKVAPDRFEILGTVEHIHYVGKC"
                     /name="PilI type IV pilus biogenesis protein"
     gene            complement(<8599..8904)
                     /locus_tag="U0533_RS26500"
                     /old_locus_tag="U0533_26500"
                     /pseudo=""
     CDS             complement(<8599..8904)
                     /locus_tag="U0533_RS26500"
                     /old_locus_tag="U0533_26500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(8914..9378)
                     /locus_tag="U0533_RS26505"
                     /old_locus_tag="U0533_26505"
     CDS             complement(8914..9378)
                     /locus_tag="U0533_RS26505"
                     /old_locus_tag="U0533_26505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_000697615.1"
                     /translation="MKILIIFALYILSPSLYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYEHYNTDNALADLQQEARSQKRGLWADPNPVPPWEWRHK"
                     /name="thermonuclease family protein"
     gene            complement(9382..10116)
                     /gene="mobC"
                     /locus_tag="U0533_RS26510"
                     /old_locus_tag="U0533_26510"
     CDS             complement(9382..10116)
                     /gene="mobC"
                     /locus_tag="U0533_RS26510"
                     /old_locus_tag="U0533_26510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_000905147.1"
                     /translation="MLIHDFYERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RNPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGVIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDAKNREMFIFRTIDELEQ"
                     /name="mobC"
     gene            complement(10126..11853)
                     /locus_tag="U0533_RS26515"
                     /old_locus_tag="U0533_26515"
     CDS             complement(10126..11853)
                     /locus_tag="U0533_RS26515"
                     /old_locus_tag="U0533_26515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_327058926.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYINGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDVPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(12663..12968)
                     /locus_tag="U0533_RS26520"
                     /old_locus_tag="U0533_26520"
     CDS             complement(12663..12968)
                     /locus_tag="U0533_RS26520"
                     /old_locus_tag="U0533_26520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000910475.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     RLMRGLIEHTVKLKSSDANKLISYAASQGYEITEDRYNAAIKAEDECLTEITRAQV"
                     /name="hypothetical protein"
     gene            complement(12996..13211)
                     /locus_tag="U0533_RS26525"
                     /old_locus_tag="U0533_26525"
     CDS             complement(12996..13211)
                     /locus_tag="U0533_RS26525"
                     /old_locus_tag="U0533_26525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001090643.1"
                     /translation="MNTDENMVFYLTNSDLVYSYAHKIVCSIPSGMKGNFITSIGETLE
                     DLKKRYPDIILITESEALALQSKREN"
                     /name="hypothetical protein"
     gene            complement(13214..13513)
                     /locus_tag="U0533_RS26530"
                     /old_locus_tag="U0533_26530"
     CDS             complement(13214..13513)
                     /locus_tag="U0533_RS26530"
                     /old_locus_tag="U0533_26530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000716758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000716758.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGGEC
                     RSAEKAFFNILKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(13542..13940)
                     /locus_tag="U0533_RS26535"
                     /old_locus_tag="U0533_26535"
     CDS             complement(13542..13940)
                     /locus_tag="U0533_RS26535"
                     /old_locus_tag="U0533_26535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_021533590.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNEKLPEWNPN
                     SLIIKSPVINDKWTLSISSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFSAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(13937..14962)
                     /gene="virB11"
                     /locus_tag="U0533_RS26540"
                     /old_locus_tag="U0533_26540"
     CDS             complement(13937..14962)
                     /gene="virB11"
                     /locus_tag="U0533_RS26540"
                     /old_locus_tag="U0533_26540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000125556.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYKSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNVRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            complement(14952..15143)
                     /locus_tag="U0533_RS26545"
                     /old_locus_tag="U0533_26545"
     CDS             complement(14952..15143)
                     /locus_tag="U0533_RS26545"
                     /old_locus_tag="U0533_26545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000995652.1"
                     /translation="MNCKDKETWLHMLAAGHMGGLAGNPNEAAAQDAYQRLIKNKTAQA
                     VLQRCTTRITLKGANDDR"
                     /name="hypothetical protein"
     gene            complement(15127..16392)
                     /gene="virB10"
                     /locus_tag="U0533_RS26550"
                     /old_locus_tag="U0533_26550"
     CDS             complement(15127..16392)
                     /gene="virB10"
                     /locus_tag="U0533_RS26550"
                     /old_locus_tag="U0533_26550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000129037.1"
                     /translation="MTDENKSPSTEEEKPVMTSDQDDIATLEREARAKREAELQASQDD
                     EKENSLQPAVNKLKKRQKGKAAAFLAICAVALIGLTWGGNWVYQNFLKQENGEKTKEVT
                     PPKKTNDYRKRTDLGMATNEPENSTEGEQAVSQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGKIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRLKNELQR"
                     /name="virB10"
     gene            complement(16434..17339)
                     /gene="virB9"
                     /locus_tag="U0533_RS26555"
                     /old_locus_tag="U0533_26555"
     CDS             complement(16434..17339)
                     /gene="virB9"
                     /locus_tag="U0533_RS26555"
                     /old_locus_tag="U0533_26555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001230135.1"
                     /translation="MRKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQTQIQKALRTAQTPRNWDYTKYPGKDSYNIEPDFAYDDGRFTFLGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQEITPRLVLRSGDAVVGLKNNGFGKVH
                     AADNSTVSDKVERVEKTDNT"
                     /name="virB9"
     gene            complement(17339..18022)
                     /locus_tag="U0533_RS26560"
                     /old_locus_tag="U0533_26560"
     CDS             complement(17339..18022)
                     /locus_tag="U0533_RS26560"
                     /old_locus_tag="U0533_26560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000139290.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLITILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            complement(18015..18158)
                     /locus_tag="U0533_RS26565"
                     /old_locus_tag="U0533_26565"
     CDS             complement(18015..18158)
                     /locus_tag="U0533_RS26565"
                     /old_locus_tag="U0533_26565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000825480.1"
                     /translation="MKRLIALALLCVLSGCAQKSKSLPHAFSGQGSPVNTPQIIAELTT
                     HD"
                     /name="hypothetical protein"
     gene            complement(18208..19278)
                     /locus_tag="U0533_RS26570"
                     /old_locus_tag="U0533_26570"
     CDS             complement(18208..19278)
                     /locus_tag="U0533_RS26570"
                     /old_locus_tag="U0533_26570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_024187435.1"
                     /translation="MMAGIFSSVEKNIIGGITDATNGLMMSYSSMMMGLAATSATIYIM
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGIKEGFSSSTSI
                     WQLLDTLWNSARVLGKTLHDLDNSEFIKEEGTIAELFVWGGVFVLMIITAFVSMIAEIM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAAILTIMFSALALRIVIGFLTSRMSEA
                     VTQASKANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     SAPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            complement(19288..19515)
                     /locus_tag="U0533_RS26575"
                     /old_locus_tag="U0533_26575"
     CDS             complement(19288..19515)
                     /locus_tag="U0533_RS26575"
                     /old_locus_tag="U0533_26575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000720509.1"
                     /translation="MKKIILFTIISGLMALTSGCKEEAKTTKWYREHPDELKVVYAECQ
                     KTGSASENCKHANEAHWQIQQLNAPEISFN"
                     /name="EexN family lipoprotein"
     gene            complement(19527..20231)
                     /locus_tag="U0533_RS26580"
                     /old_locus_tag="U0533_26580"
     CDS             complement(19527..20231)
                     /locus_tag="U0533_RS26580"
                     /old_locus_tag="U0533_26580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000819778.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLADERRKKWN
                     QQQLNAPEIMFN"
                     /name="type IV secretion system protein"
     gene            complement(20246..22990)
                     /locus_tag="U0533_RS26585"
                     /old_locus_tag="U0533_26585"
     CDS             complement(20246..22990)
                     /locus_tag="U0533_RS26585"
                     /old_locus_tag="U0533_26585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_001096400.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLFLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLLTHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLIADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDAKTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(23003..23299)
                     /locus_tag="U0533_RS26590"
                     /old_locus_tag="U0533_26590"
     CDS             complement(23003..23299)
                     /locus_tag="U0533_RS26590"
                     /old_locus_tag="U0533_26590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000608756.1"
                     /translation="MINKLKAICSRASAYILAPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            complement(23303..24007)
                     /locus_tag="U0533_RS26595"
                     /old_locus_tag="U0533_26595"
     CDS             complement(23303..24007)
                     /locus_tag="U0533_RS26595"
                     /old_locus_tag="U0533_26595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000953548.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTRDDIATQSAILNATPVEAPTRPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(24023..24229)
                     /locus_tag="U0533_RS26600"
                     /old_locus_tag="U0533_26600"
     CDS             complement(24023..24229)
                     /locus_tag="U0533_RS26600"
                     /old_locus_tag="U0533_26600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125884.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNGKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     Typing          complement(9386..10116)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.361"
                     /coverage="100.0"
                     /evalue="9.03e-162"
     Typing          complement(17343..18022)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.463"
                     /coverage="100.0"
                     /evalue="4.2000000000000004e-119"
     Typing          complement(20250..22990)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.418"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agatttagcc tggcctatag ggttcggcat gagtttatag ctcctgtatg aaatatccgt
       61 gtgcaaaagc acagcggtac gactggagaa ggaatgaagg tctggtttac tgattctgta
      121 aaagcctgga gaaggccgtt tgacgttcta acggtgagat gattgaagat atgcgttgaa
      181 tttctgccag taggtcacta ccgatgttac ggcactctat ggaatcatca tcaggattta
      241 gcgccagtat cttggcgcat ttaatagcga taacgacttt ttccggtaca gtacatattg
      301 tggaaccgaa acttacgaag ccaattgcac ctggaataga ggttattgct gatgtgtgcg
      361 tgacattcac atcaaaatgg aggaagaggt agttaggaaa taaaactttt tcttccttgc
      421 gtactgcgtt gcaatctttc cgaggtgtga tctttatgta tctcggacag aaagccacaa
      481 cgttcatagt tttacaacga tatgcaatgc ggtctaaatc gttgttatta caatatagaa
      541 gataccatgc attcataagc gtcaccttac ggacacaagc ccccattttc cgccgtccta
      601 agttgccggg cttaggctgg cgtactcatt aagtgttaac tgtaaaaata cacagttgtg
      661 attttataca gcaattcttg cgtgtcaata tcaagaatct aaagaaataa tagcattact
      721 cgattcaaaa tcaaccccga ttcattatgt tgactttgag gcctgtaacg ccctgtaaga
      781 tgggattccc aaaaaaaggg aggttgtatt atggtgccta aacgactgaa agaagcgagg
      841 atggaggctg gattatctca agaaaaatta tctcaacttc ttggtgtagc ggaaggtatt
      901 aacactcgat ctcgattttc aagctacgag gtaggcagaa ctgaaccacc ttttaaactt
      961 gtaaaaaaaa tcgcagaact tcttgattat cctgaaaatt atttctatac agaagacgat
     1021 gattttgcaa aggctgttct tgattttcac cgaaaacgta cgagtccaga gctaaaccct
     1081 aattacgatt cggaagtaga agcaagaaga atggcatcta agctggataa cgtaaaaaaa
     1141 atagttgctc aattaaatga atatctaaag gaatgagtgc ttaggcatca gtgcgtatgt
     1201 gctccatttg gtcaagtcgc ttttccgctt cctcacccac tcgctcacta acgttcggtc
     1261 gctagggttg tggcgagcgg taaataccct attaaattcc gttatttttc cgtttgttat
     1321 cgccgatttc ttttcgatat taatgctaat gtatgcgtac attagcatta atatcgtgag
     1381 ttatatgctg tacagtattt aatctcaatt ttgttaagaa ttatataacc agatgaagtt
     1441 taaagaaaaa taggaaggta atcggcggga tcttttgtgg atgaattgat cttcgaatgg
     1501 gttcatgcta ttttcgtgcg gtttttacgg atttttgggt gggacgttcc cgtaacagcg
     1561 tctaggggaa gggggggaag cattttagcc cccctgaatg caacaacccc ctgatatctc
     1621 tcttcgattt tgccggtcca agaagataat cagggggtcc aaagcaggct gggtgcctgc
     1681 aaaggattat agcaaatgca tttctcaata caagacctct gtccggcaat aagtgcgggc
     1741 ggtggtggct gaaaagaaca actccttaat cccccgcata tcgccgtcag gggtggcaaa
     1801 acaaagtcca tgctataacg ttgtgtcgcg taagcgacgc cgtttcctca atcgctggat
     1861 taaatcgctg acgacggtcg cagggcgtat caaaatcaaa aacgaactcc gccgccgtat
     1921 ccggcataac cgctattggg ttaatgaggc taacaagttt ggcatagagg ctctttgcga
     1981 attgatgtta gctattctgg acgatctcga tttacgctcg tgggaaacca ggcataacct
     2041 tgaaacgctt gccgaacgtg ccggactggt tacacgcagc gatgcgggac ataaatccat
     2101 ttctcgcgcc agtcgtggtt gtgatcgcct ggtttggttg aatgccatca ttacagagaa
     2161 ggctccgttt aacccgtatg atgcacggtg tgcctgtaaa cacattgaag taaccgagga
     2221 tttctttgcc atccttggca ttccgttaaa actggtttat cgggaacgtg ccaggctgtt
     2281 aaaggcagat cctgatgaag tgatttactc cggtgatgcc agacttatag ctatcagagt
     2341 tcagaactgg acgcggaaag cggcagccgg attagccagg atgaaagcaa aacgcgacgc
     2401 agctcgacaa cgcaaaaaag aatattacgc acattcacct acccccattc cggcctgatg
     2461 ctggctactt accgccttat ggcggtatat cgtcacgtcc ataataaatc tctgtacaaa
     2521 aaatagtctt agcgtgagat atttccgttt tccaagcggc tccctgctca ggaaagagca
     2581 gccataggtt atggccagag ggtaaacgat gtacagcttg tggataatca taagtgaagt
     2641 gcaaacgata tgacgcaatt actcttttgc ttctctttta gttacttacg tactaaaaga
     2701 gaagcaaaaa gaaaaacatt actgttatcc ccttttacaa gtggataact gaaaaacatc
     2761 ggcgcaagcg cctcaaaggt agcacccctc gcaagcatcg gggcattaga gacaccatat
     2821 ccggtcatta aaaacgaaca atcattcacc tatcatcgct gtaacatcga cggtctacga
     2881 ccacctacca cctaagtagc tgtaagttcc gtgcaatttt ggcttagcag ggggctgacg
     2941 cggttcctgg cgacatgaac gtccttgatt aggggtatcg gcgcgcctta gcatttgtga
     3001 ttctatggaa ctatatttcg cgccttacat gccgctaacg cggcatcttc ccaccatcga
     3061 gcataactta actaactgct aacaatatga tcgagaaaga tcaaaaaaag gttcctgttg
     3121 ggggtcagtt tggaaatcgg aaatttcggc gtttccggtg tacaacccta ggaaagtaga
     3181 tccgctcgcc gcaaccctag cgaccgaacg ttagtgagcg agtgggtgag gaagcggaat
     3241 agtgcccttg ctgaattgag cacatacgcg aaggaattaa aggtgagtgg tggaaaattt
     3301 ttcagttcga atagtgaaaa atagttgcaa tacctgcata tgcaggtata ataaaatcat
     3361 cgaaagggaa ataggttccc tttccactta gccccatagg ggcgggagat taaaatgagt
     3421 gcatttattt ttagaaccac atttaaagca actggcgatc agcaaaaaga cgctattacc
     3481 caaattgaag ttatgcagga acaagcagta aaagcctttg tttcctggat gaccaaccag
     3541 gagggtacag aatttttaag cactttgcag gaaatcacaa cagaacttga cgcactgatt
     3601 gatgcggtag agtcccattc ccctgttttc agaaagaaag cgactgaact ggaagcgctt
     3661 ttagcccatt acaaaacgtt gctgtaagtc ctcaacgggg caatcgcccc gttatatggc
     3721 tctttattta atccaaatct aaagcaagtg gagtttaaaa atggctcgct taccttatat
     3781 tgaatcaacc acgcaacaga tttttatttt taatactttg acactttgta ctattggatt
     3841 aattcatata gagactggtg aaaaatatat tgtagtattt acagataaca ataagattag
     3901 agattataaa aatggtgtaa tagaagaatt aggggaaatt acgcaagaag atattgaact
     3961 gattgagtat tatgctaaaa aatatgaaaa gtattttgat gatttaaaaa taggtgagga
     4021 gcctttgaat cttaaagaat atatagaatg tatgcaatag ccatatattc tataaaggtg
     4081 tgatcaggtt ggtcgagcaa cctgatcact ttatcgacac tcaaaacaat agagaggtgt
     4141 tcaaatgtca acaggtcaga tcgtacaact tgcggattca cttgtcaaag gatgggaaac
     4201 gagaatccca gcaatgaaat ttacggattg ggatcaattc aggtggtggt taaattattt
     4261 acagggatat gaaatgtttt aagcaatgtt gatgtcctga cagtaattat aaattttttc
     4321 aaaaagagag ctaaaaaact tgcaatacct gcaattgaag gtataattaa atcatcgaga
     4381 gggaaatggt ttccctctca tcttagcccc acaggggcgg gagctacaaa atgaatatcc
     4441 aagaagcatt aaatattttt ggcttgtctg gccagttgac tgaaaaagac atcaaaaacg
     4501 cctttaagaa agctgcatta aaatatcacc cagaccgtaa tccggtaggt gctgaaatga
     4561 tgaaggcggt taattcagca ttcgattttt taatggcgaa tcttgataag attaatcact
     4621 accaaagtcc tgaacaaagt gcaatatata actatggtga tgaactagaa aatgttttaa
     4681 aggctcttta cggtttgtct ggtttagttt atgaggttat tggtaactgg atctggatta
     4741 gtggaaatac tatcgagcac aaagaagcat taaaagaaat agggtgtaaa tgggcggcaa
     4801 agaaaaaaca atggttttat cgtccagaag aacataaaag ttactggaac cgtgaagagc
     4861 acacgataga ggaaatccgc gcaaaatatg gcacaagcgg aaaattccag gccggaggat
     4921 ggcaacaagt tgaaggcagg gcaagagttg aagccagagc ataacgaaac gggggcgtaa
     4981 gccccctata tcctcgccag caatcctttt cgggcatcga acccgaaaag gattgagtag
     5041 ctgacactct gcgattgctg gctacgttag cgcagtaaag gatttgaaag catgacaaca
     5101 ttttcagaaa aatatcagcc tgtctttgaa gttgtatgcc gtattcttgg gaacggctgg
     5161 cgtgttaaca aactggataa ttatcagcat cgtattaaac tgacttctac agaaattcgt
     5221 aaatactcca tcattattcg tctggagcgt gaaagatttt ttatagttgg tagcgttgat
     5281 agtcttgtat ggcacggtaa tccttccgtc tgtactgtat ctcttacgcg caatcctgtt
     5341 ggtattgcta atgatatatc tcggaaaatc cttgctaatg cactggatga aattgaattg
     5401 ctcagggagc atgagagcgc attacaggaa aaacaagata aagtgcgaat aatcaaaggg
     5461 atgttatcac agttgctttc tatatctccc tggtatgggg cattaacggg atttaatgcg
     5521 gataatggac ttgcaggaaa aatactacaa aatggtgatg attatgaaat ggttatcaga
     5581 gggcttaatg ttgatcaact tatcaaagtg gcaggtttta taaaaaaact ataacaaagt
     5641 gttgatgtga attttatatg gggttgttta tgaaaactga taatgttttc tttaaaagta
     5701 agggtagtta ctcttatgtt gttacagtag atatggataa tcagatgtat atggtcagaa
     5761 agtatgttaa gacatatgtg aaatcttgtg ataaagagca agttaaaggg aaaaagacag
     5821 ttaaaaaatt ggtgctcgat acgaatctta cattgccaga attattggat cttgataatg
     5881 gtattctggc tgatttattt acaagaggta ataacaatgc aaactaaacc aactccggca
     5941 gatgttaaag aggcgagaat ttccgcaggt ttaacgctta aggaagctgc cgaaattttt
     6001 ggctatcagt taaatacctg gcaaatgaaa gaaagcgcag gtaaagctac aaggtcttta
     6061 tctgtaggtg aatataacta cttattgttg ttggctggaa aacaccctga atatgttctt
     6121 tgtaaaaggg atacgatcac cgcagaacca accactgtct gaccccaaaa ggggcttttc
     6181 gccccttttc tactaaatgt taaaggccac tcgctttccg gtagggagtt caacatctag
     6241 gctcaacttt cctcccatag cttcaacgta acgctttaac gttgccagct tcaaatcatt
     6301 tccgcgctgt tccagttgag ttacagcggg ctgactgatt cccattgcat cagcaacctg
     6361 tttttgtgaa agctgcaatt cttcacgcat catttgcagc cctgtttcca gaatcatctc
     6421 atcagccata gctttgatga tcgcctgact ttcaggtgat tgagccgcaa ttacttcttc
     6481 taatgttctc attttttgcc ctccagttcg gctaagtgag tggaaaattc ttcgtcagca
     6541 atacgaatca ttctgtcgta aaatttctta tcattacttt tgtcgccagc gcaaagaatg
     6601 attgcttgtc taattggatc aaatgcaaag aatgccctga ttgggtgtcc ctcatattgt
     6661 atacgtagtt ccttcatatt cttatgacgt gaccctttca ctgtatctgc atgtggccgt
     6721 gaaagagagg ggccaaactc ttcaagatgt ttaagttcag ccagcacttt tcgttttagg
     6781 gctagttcct gctcttcaaa ccattcatca aataatctgc caaaataaac agtccacatg
     6841 tcccttttcc tataagttat agcttataga tgattgtata agctacgact tataatttca
     6901 agggaaacgg ggctatttaa cataatggac gttatcggca ccatcggatc accgttcgtt
     6961 gtcggatctg caaaatccgc tcaaaagatc atgttttcct gggcgttttc caccgttttt
     7021 tatgttgcgt atttgttaat aaaacgtcat tttttgtttt ggctgaattt ggttgtgaaa
     7081 gccttatatt cacaagttat ctcttcactt gccgcctgta gttcaaatag ttgttgcaat
     7141 tcttggcacc aatacggata ctataattat atttttctat aaaaatattt ttataggggg
     7201 tcgtatgacg gtagctattg cgctggttaa cggtaaaggc ggggtgaaaa agtcctcaat
     7261 gagcagggct attgccacag agtacacgaa ggcagactgg aaggtattag ggcttgatat
     7321 ggatgttgat caggggtcat tcctggattg gggacagcgg cgattgagat ataaagttga
     7381 accacctgtc actattcagg gatgcggaac ggtatcacag gctaaaaaac atattgaatc
     7441 agggatatgg gatttagttg ttatcgatag tgctgcttat gcaactaaat cgctgttgag
     7501 cctggcagaa attgttgatt tgctcgtgtt accgtctggt tttagtgtgg acgatttgag
     7561 aacgacggtt acaaccgtga atgcattgcg taacaaggga cactcaacaa ataagatggc
     7621 tgtagttttt gtcggagtca gtgaaagcga aagtgagtat cgtaccgcgc ttgaatatct
     7681 taaaccgtgc ggtgttcaag ttatcaatgg cgcaatacct tttatgacct cgttcagcca
     7741 ggcacaggat aaaggactgg cattgacgga atcccctttt ccaggtccac ggcagaaagc
     7801 tgacgaagtt gtccagggag ttattgactt gctgactaaa ctctcacagt gatatataat
     7861 tctataatta tatttttata gaggtgataa gatggctaat gtaccaccaa aaccgcgtaa
     7921 caccaaaggc gagccgccaa gtctggagga tacacaacac ggatttaatc cgacgcgtaa
     7981 aaacgctgat gggagaaaag ctcagcttaa cctttatgtg gatatggaag ttaaacggga
     8041 gttccgctcg attgcagcgg ctaatgatat gaagcacggg gagttgctgg aggcatacca
     8101 ggaattctgg aaaaagcatc attaaaatgg cataggggac gaactgtccc ctgatattaa
     8161 cacttaccaa cataatgaat atgttcaacg gttcctaaaa tctcaaaacg atcgggagct
     8221 acctttcgcc agtgattttt ggcacgagag gcatagcttc tgtcccagcg gagaatacga
     8281 ttattgtcct ggataacaca taccatcctg ttttctgctg tacgcaatga ttttgtaatt
     8341 ttagctaaat cattatctgg acttagatca attagttttt catggccgtc atttgacaca
     8401 acgagtattt ttatcgtcat tatcgtctcc attatcatat tctggaaaca ctattagtaa
     8461 cgcttcgccg ttggtgcgtt tcataaaatt gaacactaat ctgcctactt cttcatttgt
     8521 catatagcgt tctattggca atgtttcgta ttgatccgca tagagaatat tcacactttc
     8581 ttcttctggt tctgaaatct ggccaattgt gatatctgtc agacctgtat cagtgaaatt
     8641 tcctgatttt atgtcaaagt cgctatcttt gaatttgtat gcatcctgcc atacagcgaa
     8701 acaagtgtgg caggtgatgg gcagttcgcc ttcagccagc ttttcacaat tttgaaccag
     8761 tactcgctct tggttgtact gtaagttata gccacctgta caaagcgttt catacccatg
     8821 agcgccagtt acgatatgtg tcgcaaccct ttccaggact ttcccattca ctaataactg
     8881 ttcacgtgtg gtaattgttt gcatgtcaat ctcctattta tgtcgccatt cccacggtgg
     8941 aacgggattg gggtcagccc acaaacctcg tttttgtgag cgagcttcct gttgtagatc
     9001 tgccagagcg ttatctgtgt tgtaatgctc atacacccat gcagcacccg attgcaccat
     9061 aaagcggtta gcctcactac cgcctgttgt gaatacacgt ccgataatgc gaccgtaacg
     9121 gtcgttgtgt gaatatgtca ccctgacgga ttgtccggca atcaggcttt taagttggtc
     9181 agttgaccag cgtccgtaag cctgtttctt ttccggtgca tcaatattgg ccagacgaat
     9241 ccttactggc gttttattct gtaaaatttc gatggtatcg ccgtcaagta cacgaataac
     9301 ttttccctgt atatccgctg cattggcata tagtgaaggc gacaagatat ataatgcgaa
     9361 tatgattaat attttcatca actattgttc cagttcatca attgttctaa aaataaacat
     9421 ctctctgttt tttgcatcaa aaggcacagg tgtattattc ctcattacag ttttgattga
     9481 gtcgaacagt ctgattaatg attctttact tttggtgtca ggcatgacgt acaaagcata
     9541 atgccagttt cctttatctc ttgccgtaag atgactgttt ataatgctta tatagcgagc
     9601 acgagttttc attgttcgtt ctgtttcaat agccattatt gcgccagttg gttgttttat
     9661 tactccatca gggcgatggg aacagccgga ataacgtgcg atgaaggctg cactatcacc
     9721 gttaatccat tcagtagcgc ctttactttc cagagatatt ctcactcgct gatttaaaag
     9781 acgatgctca agagtccagt attttagttt gctgggttcg aaataactag ggaacgtaat
     9841 gtcatcggct tttacaacca ttgctaatcc ttgcatagta ataccccaaa cagttaattt
     9901 tctttttgat gatggtattt catgtttgat aataaaacct tctttaagag ccttgtttag
     9961 taatttatat actgggtttc tgcttttttt tgtgaatcct aattttcttt ttataatgtg
    10021 aaagtctgaa tacgtttcat ccttaaggaa atttaaaaga caaagcatgt tgttagctga
    10081 tattcttttt ctttcgtaaa aatcatgaat taacatagta aaacctcata aaccactgga
    10141 aggcacatcg ttgttattgt gttgttctat ttgttctgtc tcaaaagata gcaattcaat
    10201 ggtttctttg tttgctggta tatgagacat tttagttgct tttggtaaat cttttgatgt
    10261 gaacacaaat cctactcttt caggtagatt taaaaacata ttactgtcta cataataact
    10321 ttctgcctgt cttatcatgc ggtcagtatc aactttttct gttaatgata agtcggttct
    10381 caccttcctc atttcatcgt caactaatat tgaaccagtc attttagctg cccactctgc
    10441 tgtttctgga ttctggattt tatagattaa cttgaatttt gcgttttcaa taacagcacc
    10501 aattacagaa tcgccattaa gatcagaagg gcaatctctt aaatcatcta ttgcctggaa
    10561 ggccataaat atatgcacac ttttatctcg tgctgtacct aatccttcca ttgtcgggcg
    10621 tgaaatatga tatttcaact catcaagaaa aattgcaaca acacgtggag ttgtgtttat
    10681 tctgtctctg gtttcagcta tctgaatcaa acgcgtaagt atcatgcgtt gtgcagaaat
    10741 aattttttga tttcgggttg acccattgat atagcagcat cctccattat caaaaatctc
    10801 tttaagagaa aatccatttt ttgcattgac ggaatttaca agagcaattt cttctagttc
    10861 acctaaaaat gctggggcat cttctcctat tgattttacg ttgtcatcgt tgaataaatc
    10921 atacagtgtc attccggttt tatgaattgc ggctacattt ctggctgcgc ggcgatcagc
    10981 tatacgataa aaatctgcgg cctctccttt ttttgataga ctaaatcctg cattaaataa
    11041 ttcttctaat tgttcatgtg atatgtcagc aagtaagtca agttgatggt tggttctgtt
    11101 taaattaatt acaacaaatt tctttcctgc ttttttacat gcttccctaa gaacatgcac
    11161 agcccattca tcatcttttg gatcttcaac aaaaacagcc tcgcctaaca gaattgcctg
    11221 ataaagcaaa accgatgcgg taatgccctt accggaacct gttgtaccta tgattgctgc
    11281 atgttgtttc tgaaattctt ttattgttat atattgcggt tggtcgtctt tgtctaagcc
    11341 aatgaaaacc ccttttttca aatcaatgta atctagggga ttgtattcta tgctgtctgg
    11401 caacaattct tttactttgc gaacatctgt tcttgtattt ctctcaagtt tgcttttctt
    11461 tatcattctg tgtttcaggc tgtctatttc acctgctaat aatcgtcgcg cggtcaaatg
    11521 aaaagctaat ccagctagtg taaagagaat tgtgattatc cataatggta ttctaagtag
    11581 tgtattggga tcgagaacgt caaataggta gctcagacca tgaatactaa gtggtgacat
    11641 tgtgccgaat atgaaaaaga aaatggacac gcacgcaaca gattttaacc agaagggagc
    11701 gttttttctt tcctctcgtg gtaggttgaa tataaatggt agtgttagtc ctgccagtaa
    11761 tgacaatatg acagggctgt tctgtagcca taacagaaat attgaaaagg catcagcaat
    11821 accattcagc ttttgcatta gatgtggatt catatttgtt ttccccattc ataaagtgaa
    11881 tctatggggt acgacaatgg ggtacagtaa tgggggatat aatgtacccc atagctgtac
    11941 cccattattg taccccaata aaagccaaaa acgttgtgat cgcctaaggc gatcatgccc
    12001 gttatccgtt ctttcagaag ccagccgata agttatcgtc tggctcctga aagcccgaag
    12061 aacgggcaac ggcgtgtgcc gtttcggcct ggctgaaacg ccagtccttc acgtcacatg
    12121 ggggtaatgg cccgtctgga cgccggacca aaacccccaa ggtcaaaggc ggcacaccgt
    12181 cgcgcgctac gcgcgaccac cccctttaag acgcgcgttt agcctatttt ttcttcgcaa
    12241 gctcgaaaaa attggaacgc tgctttaaag ggggtggtcg cgcctaatcg gtaatatccc
    12301 ccgctggggc gggaaatatt acctggcccg acggtgtgcg gggcaagccc cccacaaaaa
    12361 ccggcacgtg ggcgtgcctt ttttctcgct ggggcggaaa aatttttgcg gctccccccg
    12421 gcccgcttca attcgcttgg ggcgaatgtt cgcgggtggg cgtggtgcct gaaaattaac
    12481 aatttcttcg aaattgaatt ttctgtccac gcaccacttt ctttattcct gtcttaacaa
    12541 tttcttcgaa attgaagcca gaaataaaga aagcctgaac tgcaccacgc cctgcgtcgg
    12601 actcgcccaa attcgcaaag cgaatttgcc ccgcccttcg ggttgctacg caatcctctg
    12661 cctcagacct gtgcccgtgt tatttcagtc agacattcat cctcggcttt tattgcagca
    12721 ttatatctgt cttctgttat ttcataacct tgtgaagcag cgtaactaat cagcttattg
    12781 gcatcagaac ttttcagttt tactgtgtgc tcaattaacc ctcgcattaa cctcgcttga
    12841 tatatttcat aatatagccc gcatcccctg tttgctttat tactaatatc atcaaagact
    12901 ctttttacat ggattctgtc ctgattcctt gaatgaatat tattaatgaa catatcttct
    12961 tttaacatag gattctccag atctgaaaga atatgttaat tttccctctt cgattgcaat
    13021 gctaatgctt ccgattctgt aatgagaata atatcaggat atcgtttctt taaatcttca
    13081 agcgtttcgc cgatagaagt aatgaaattc cctttcattc ctgatggaat ggagcacact
    13141 atcttgtgtg catagctata aacaagatcg gagtttgtca gataaaatac catgttttca
    13201 tctgtattca tatttaccct cgaactctac caaacttact cattattttt gatatagctg
    13261 cgggatcagc ggatgaacac tgatttaaaa atgctttacg tgcatcaaat gttttactcc
    13321 atcgtattga acctttcttt ttcttaagaa tgttgaagaa tgctttttct gctgatctgc
    13381 attcgccacc tccgctgttt cctgtagctt ttccgtacat acataaaaca acctcgcatg
    13441 ggtctgcggc ataagagtaa acaggtgtgg cggttgttaa aacaaacatt gttattgctg
    13501 caattttttt catgtcagaa ccctttgttt aatattttgt gttaacgcga aaagtagatg
    13561 gttgtttcat tgcacgtaag acaatttgtg atggggtgat atataattac cccgtttgca
    13621 ccatgatgat acaaccagtt ttttgcactg aaataatcag cgcctgactt tgttgctact
    13681 gtgatttgtg ttgagtgagc aatggcataa aagacagatg gcatccaatc ttctttattg
    13741 aaatcttgtg agctaatgga taacgtccat ttgtcattaa taacaggcga ttttattatt
    13801 aagctattgg ggttccattc aggaagtttc tcgttaagcg ataccggctt tttattccat
    13861 tccacgggta ctggtggagg cggtgaggaa catccggtaa ttagtgttac aagcacagta
    13921 accagtatat gctttatcat actttcattt cctcgtaata ttgattgcgg tgtaacggtc
    13981 ggaaataaat atcattcata cggcgtacgt ttccatctaa atcaatgctc acaacaacat
    14041 ccagagagtc gagaacttta cgtagcaaga atgaatatgg taattgcgca cactgtgggt
    14101 tttcagtaca gcgggtaata aaaccgtcga ttgcttcatg ggctgaacca gcatgaatgg
    14161 aggtcatact tccttcatgg cctgaccccg ttattttcag aaaatcccat gcctctccac
    14221 ccctcacttc tgttaataaa attctgtctg gattcatccg gtaattccag cgtataagcg
    14281 ccgctggtgt tacaacagaa cctttttcat cggatgactc agaaggataa aacagatgaa
    14341 catagttctt atgtttgtag aatattatct ctgggttgtc ttctatcgtc gttatgcgta
    14401 aatggacggg tatatattgt atcaacattt tcatgtatgt tgttttaccc gtactggttt
    14461 cacctgcgac ggctaatgtt tttccatact ccacacattt ttccataaac aaaggaatgt
    14521 tttttgattt gtataattca atcaattctt cgttatgtgt ggatgctttt tcaatgcctg
    14581 tgacgcggtt ataaaaaccg ctatcaatat atgcctgatg cggaatttga atttttgacg
    14641 gtttacggat cgtgattgag atcgtgtcac gttcgcacgc cggaggtacg acaacctgac
    14701 atcgttctcc tgattccagg gttgcagaaa gtcctggttt gatatcctcg atattatcgt
    14761 tatggtgttt tgcaagacac cgagcaaagt tatagcaatc gtcaaatttc agatcaacgg
    14821 tatgttgccc ccagacacca tctatctttg tccagagttc acctggacga ttaacagcta
    14881 tttctgtcag tcctggtaat tccagaaagt caccaaaaaa tcgctgttta tagcggtcca
    14941 gggaaatatt cttagcggtc atcgtttgct cctttcagtg tgattctggt ggtacaccgc
    15001 tgcaaaacgg cctgtgcggt tttgttttta atcagacgct ggtaagcatc ctgtgcggcg
    15061 gcttcgttcg ggttcccggc gagacccccc atgtgtccgg cggcgagcat gtgcaaccaa
    15121 gtctctttat ctttgcagtt catttttcag cctcagcgtg tagatatttg aaaagtcaat
    15181 atcctgccct gtaatcaggt tgataatttc gccctggttt ttgtagagcg taggggggat
    15241 attgatactg ttttccagcg tggttcgagc catatccgcc atagcctggc ggctgttctc
    15301 tgtatagtct gtattgcggt cttttttacc cgcattgttt gatgcccatg cgccaatatc
    15361 tgggatcatg ccgaccatta atgcgccgcc aaacctctcc cagaagtggg tatcaatcca
    15421 tccatcaaca cctgattctc caagctcgcc agcggcgttg gtatcaatca gcggaatatc
    15481 cagatatggt cgctgtcggg tgcgtaattt tgtcatcatg ataaaagcgc gcccctgccc
    15541 ttgcgtaatt cctgtctggt atattcctgt tgctgtggtt cccttctcga taagttttgt
    15601 attgccgctg gcactccaga tatctttagc taccgtacat cgtatttttc cagcgcgatc
    15661 ggaaacaaag cggtaatcca tagagcatgg aatgactgtg ttttccggta tgtacaaatc
    15721 agggttgtag gggattcttc gcactgttgc gggggaaatt gcctgtgatg cagtgccatg
    15781 ttgtgttgtg gttgctgtac tgtctgtagg ctgtgtggcg ttgttttccg cagccagtat
    15841 catttcctgt tgtcttgttt ttacctgatt ttgggggctg gccgtattat tacgacgaac
    15901 aaggaagctg gccttattca gttgtggtgg ctcaaatgtt ttcatctgtc cggcagtacc
    15961 ggatacattg cccgtgttat cctggctaac agcttgctca ccctcagtcg aattttccgg
    16021 ctcattggtg gccatgccta aatcggttcg tttccggtag tcattcgttt ttttaggtgg
    16081 tgtaacctcc tttgttttct ctccattttc ttgcttcagg aagttttgat atacccagtt
    16141 accgccccat gtcaggccaa tcagggctac tgcgcatatt gccagaaagg ccgctgcttt
    16201 ccccttctga cgttttttca gtttgtttac tgctggttgt aatgagttct ccttttcatc
    16261 gtcctgtgat gcttgtaatt cagcctcacg ttttgctctg gcttctcgtt ccagcgtggc
    16321 gatatcatcc tgatcagatg tcatcactgg cttttcttct tccgtagagg gggatttatt
    16381 ttcgtcagtc atatatgagt ccttatataa aaatataatt atatttttat agattaggtg
    16441 ttatctgttt tttcaacgcg ctccaccttg tcagatacgg ttgaattatc agccgcgtgt
    16501 acttttccaa agccgttatt tttcagcccc actacggcat caccggaacg taatacaagc
    16561 cgtggtgtga tttcctggat aacgagaacg gtaaaattgc ccttacgctg tatactgctg
    16621 ttaaccacgt attcctggcc gttctgttct ttggtaactg atggaactga tttgttgggt
    16681 gagaatccga gaaacgtaaa gcgaccgtcg tcgtaggcaa aatcaggttc aatgttgtaa
    16741 ctgtcttttc ctggatattt cgtgtagtcc cagttacgcg gggtttgtgc ggttctcagt
    16801 gctttctgaa tctgggtttg ttcctgcttt tgttcccatt ctttctgacg cgctgctgct
    16861 tccttattag ctctgttacg ttcgtctcct ggatagcggt aactcaccag gtatgcgggc
    16921 tgttgtggcg atttttcatc aatgacattc agctcaacgt tgtacaggcg cttatttgtc
    16981 acaatcagca tattggtatg ccagtcacgg ctgttcggcg ggataacaac ctgtgttgta
    17041 ttaccgtctt caccaggtgc gccctgtgtg agcgcaaccg gacgaatgtt taccctgttt
    17101 gcatctgctc tggcttccca tgcttcatca aagccaggac tggcactgat aacagcttca
    17161 tcgttatcaa aaaccagagt cgtcataaat cctggttttg tgtttacaac ggtaacattc
    17221 tgcgggttat aaatgacctg ctggatacgt gcatcataac ggctcgcttg tggtgtagct
    17281 gcggcccatg cctggctgtt cagcattatt atcagggtaa ttaacgtcag ttttctcatt
    17341 actcgcctcc cctgatttcg cggtcagtct gccagcttgt tacggtgaat ccgaacgggt
    17401 ttatttcccg ctcaacatct gacatttctt tttcagggtc tgaatggaag gtgaaacgtg
    17461 catcccagta ttcattgcga atactgttat cagccatgcg acgaattatt tttttataac
    17521 gaacggtggc tactttgtct ggtgctgttg cattcgttat ctgctcagaa ataatttcaa
    17581 ttttcacggt gtgagccgcg ttattataaa ctttgtctgg tgcgtttttt ccggcgtaca
    17641 gtgccaggta gtcgtcgttt acctgtggtg agttgtagat ctgtactgtc tcgtaatcgt
    17701 cctgtaatgc aggataaacg taccgttcac gtaatttaac gtaattggcg gccatagctt
    17761 tttggtaggc ttcttccgct gtcagggctg tttttgatgc acgggtaacg tgttccactc
    17821 gtccggtatg attatctacg gtatagagtt caactgttgt ttgtttaagt ggcaacataa
    17881 tcactatcgc gatcagtgac aggatagtga ttaataaccc tgctccaccg accagaaagc
    17941 ctgcttttgt ggcgcgttta tccctgtcaa tcatttgctg ctcaaacgag cgggaatcag
    18001 caattaattt ctgttcagtc atgtgtggtt agctccgcga taatttgggg tgtgtttaca
    18061 gggctaccct gaccgctgaa tgcgtgcggc agagatttag atttttgtgc gcagccagaa
    18121 agcacgcaca gcaaagccag cgcgattaag cgtttcattt tatgtacctt tttgtatttc
    18181 tataaaaata taattatatt tttatagtta tcttggagga ggtaaacgtt taattgatgg
    18241 cggtagtttt ggtgctgatt gatctgtcag catccgcgct tcattacgcg ctatcatttg
    18301 ttctatagcg tgtttacgtg catcagcagc gttaaatact atgcgcgatt gtggatctcc
    18361 taacccttta ttacttgggc ttgctacttc tttaggtaat acttttcctg cctcctttaa
    18421 catctttcca gcgccgtatg cagcagcgcc aatgccgaga gccgccgcac cttgcatagt
    18481 ggctgtagca cttgctcctg caagtgcccc agctagtttt gcggacatgt acaccagtat
    18541 tgcagcgcat actccggcaa gacaaacttg agcgccaagt tctacaatgt ttgctttgct
    18601 ggcttgggtc actgcttctg acattctgga tgtaagaaaa ccaattacaa ttcgcagagc
    18661 taaggctgaa aacataattg ttagtattgc agcaaatata ttttgaagcc agttattaaa
    18721 cattggccgt aaaaagccat acatcaggca aaatataaat attggtgcgg taatacctaa
    18781 caataagatc atgatctccg caatcataga tacgaatgct gtgataatca ttaagacaaa
    18841 gacaccaccc catacaaata attcagcaat tgtgccttcc tctttgataa attcggagtt
    18901 gtctagatca tgtaacgttt tacctaaaac tcttgcgctg ttccatagag tatcaagtaa
    18961 ttgccagatg cttgtgctac tggaaaaacc ttcttttatt ccatttacag catcaatgac
    19021 accatcaaga tatccgttaa tgtttgctac aaaggataaa atgatagcca tcctcattat
    19081 atcccacata acatcttcca ttggtgtaga cagctttccc gctaaggttt gatatcctcg
    19141 ccacataatg tagatagtgg ctgacgtagc cgccagcccc atcatcattg acgaataaga
    19201 catcatcaaa ccattagtcg cgtcagttat cccaccgatg atattttttt cgacagaaga
    19261 aaatataccg gccatgataa acgcccttta gttgaaactt atttcaggtg catttaattg
    19321 ttgaatttgc caatgagctt cattggcatg tttgcagttt tcagatgcgc tacctgtttt
    19381 ctggcattca gcataaacaa ctttgagttc atcaggatgt tcacgatacc attttgttgt
    19441 tttagcttct tccttacatc ctgaagttaa cgccatcagg cctgaaataa ttgtaaataa
    19501 aatgattttc ttcattaagt cacctgctaa ttaaacatta tttctggtgc gtttaattgc
    19561 tgctgattcc atttcttacg gcgttcatca gcaagcatct tttcacgctt ctccgccgct
    19621 tttacgttca tttcccattg ggtcgtgagc gtatttagca tcacagattt taactgaata
    19681 ctgtttgcta agtcttgggc ctctttcata tctttggcat ttgctacacg gtctgataat
    19741 tcgttgatct caccaagcat ctcaccaatc tgggtttgta cttcattggt ttgttcgatt
    19801 tgtattgctt tgttgatgac ctcttgtctg catgtattgg cataactttt tgattgttca
    19861 gcattgcagt tatcgaaaat cttgtatttg ttgtacagtt catcaaattg gccagaagaa
    19921 ccgccggata agagcaaatc gttcagggct tgccctggct tacgtagttt atccaggtca
    19981 gctttaaggc ttttggcctg attaacgaac gcctgaatgt cacggatgcc tgtaactgtt
    20041 tccagttgtt tttgatacgc ctgtagctgg tctttatagt gttgtaccgt ctgtagccat
    20101 tgattggctt cttttgtcca ctggcgaata ttctctagtc tggctgttgc atcaaacacg
    20161 ggtataccag cagcgtttac tatcgggctg gcaataagaa ccgccagaat aagggggcga
    20221 aatcttttca tcgatatctc cttggttata gtgctttagc taggtaggaa tccagccagt
    20281 cgctgggctt cattccctcc tgatagagtg attcgaatat ttccaggtta ggtgcgtcgc
    20341 cgctcattac ttttgtgtat ctgccgatac cagacagatc cagcgtgata cgggctgcaa
    20401 agcgttttgt atctccacgg cggaactgat ttttgacaac gacatactgt cgcgcctgtg
    20461 gatcaagtcc tttaatgaca tcaaacactt ctggttcaaa tttcattcca tccacgtaat
    20521 gagaacgatc tgcgcttggg ttggcggcca gtatttgagt accacattgc tcaataactg
    20581 ccggagctat ctcatccttg attatttccg ctggagattg cgtgccaaca accagcatac
    20641 cgttcagttt tcggatagtt ttcagcttgt tatacgcaaa atccttaaat acagggtcgc
    20701 gtaaccactt ccagaattca tccatgaaaa taacaagtcg tctgccatcc agcaggctgg
    20761 ttatccggta cagcagataa aacgagatag gggcgcagac attcgggtca tccagaaatt
    20821 cagtcccgtc aattccgaaa ttatcgcagt tgctgatatc gaaagtgtcg tgttcgttat
    20881 caaacaccca accaaattca ccaccgcgcg cccactgtga aagacggata ctcaggccat
    20941 tttcttgcgc ttcacgcgtt gccggttccg gtaggttctc cagcattcgg gttatgccgt
    21001 agacgcgata ttgaggctcg tcactcatga cggcatttac agcatcattg aggcgacgtt
    21061 catcacgtgg cgttatggtt gcaccgttgc gggtacaaag gattttcatc agttgcttaa
    21121 tgaaattgat gtttcgctta gtggctggca gagcaaacgg attccagcct gttggctcac
    21181 cgctgaatac cctgtagtac tttcctccaa gtgcgcgaat gttgatttca gcaccacggt
    21241 ctttatcgag gtaaactgtg gttagtcgtt tagtcttggc atccggtgaa aagctgtcat
    21301 cacggttata tttttgctga ttgatttgta aaaacgtcat cagcattgtt ttacctgagc
    21361 cgtttgtacc cagaatgcag gtacttgcag gatttttttc gttgaactcg tctttatctg
    21421 ccagagtgtt atgcagattc agatagtagc catcacctga cggggttcgc accagagcca
    21481 tcgcgtcacc ccacggggct ttgtcgcgtt ttcctggata gaaattatga agtgatgcca
    21541 gttcaacaaa gttcaggcta ctcaactctc ccgctcgtgg ccgcagattg taattgcctg
    21601 gtaattgagc catataggcc gcagacaatg agatttcagc aggaacaggg gttatcccta
    21661 tattgttgag tgcattgctg atctcgtttg tgtctgcaat cagactttcc agtgacggcg
    21721 aaaacaccat aattgataaa tgatgtttac cgtaggcgat tttaccggag gtgagcaggt
    21781 caagcgccac atcgagatcc aaacgttgag atacagcatc atcatcagca ctcatcatca
    21841 gccgtcgggt gcgcttaatc gcctttttcg cttcctcacg ggacatgcag gtataggatt
    21901 gtgtaatcac ataatcgcac ggcgcgtaca gtaaggagtc tgtcatgccc gttgcggttt
    21961 cttccgaaaa ctctttaacc tccagaccac ggaaatattg agtgccatta acatgattta
    22021 tttgccctga ttcggcggag aagtacagcg caacatttcc cattacgttg taagcggggg
    22081 tacgtgtaac tctgactttt cgccattgat gcgtgagaag gtattcataa aatgccagtt
    22141 gggacgagaa tacagcctcg ttttcggtga aagtaccgag cgcgtgagca ccataacggg
    22201 ataaggctgt atccagcgta cttttgattt ccagcacttc aagtaatgcg ctgtctatct
    22261 cttttagctt ctgaccgtct ttcatacgtt tacggtttgc cttatccaga ctggcaaacg
    22321 gacgatagca gatggtcaca aacaggcggt tacgtcggaa tggcctttta ttcagtgatg
    22381 cgtaatagcg ttcgctcacg gtatccgcgt aagggtttcc tgaaacctta tgcagtgagt
    22441 ccgtaaactg ttcacggctg ttatgtacat aaaatgtaac cggaaagcct tcaaatgagc
    22501 gtattagccc gtgcaactgg tttgtaccga actgtagtgt ctcgtcagat tcacaatcaa
    22561 acggcgttcc tgtcagttcc caggtacaga aaaaatcgct attcagtgaa cggacaacat
    22621 tagggtgaat atgtgacgag taaggaatgt atttttttat ggtggcacat tggtttagct
    22681 tcatcgcatc gataaactcc tggatatcaa cagcattatg ttcaacaggc ataaatgcgg
    22741 ttgcgccaaa taaacggttt gctaccggat taccccttac ccttagccag acagctatca
    22801 ggttaaatct cagaggttca tttctggtta gtgatttcat aaccagaaac tcaataggga
    22861 ggaagagaag tagggctatg gaagtccaga tagcaacaat aattgtcacg cccacgacag
    22921 tcagcagggg caccattggc accccccaca gcgccgccgg acgtttcatc gccttaagca
    22981 gctttgccat atgttcggcc tcttagctca ttagcagagc gccaatttca ctgcctccgc
    23041 caattaaaat gccgccaatg atgatgtaac cgcactgcga caggctttcg cctttccaca
    23101 gagtcttata gccaatccag atcacagcga cggtgatggt gacggctgcc agaccatgca
    23161 gaccattcga aaccttttcc atgatggtat ttgctcggct gaaaccgtca gccgcgaaaa
    23221 cgggactgac aacacttact aacggagcca gaatataagc agatgcgcgg ctgcaaatgg
    23281 cctttaattt gttaatcatc ggttaatcct ctttttcagt tgaaaatctg tttccgcgta
    23341 taacttgtgc ggggtaataa acggtatctg cctttttctg gcgcagttga gcaggaaccc
    23401 cgcgcacgat tgcgccaggc cagacaacgc gagggcgtgt cggagcttca acgggtgttg
    23461 cattcagaat ggccgattga gttgcgatat catccctggt tccaggaacg acatagcggg
    23521 gcttttcagg tgagtaacca attcgctgta tgtaactggt tctggataac gcagcttctg
    23581 gttgttgtcc tgtagtaaaa tttccagagt aataacaact cagcgcccgt ttcagtgtgc
    23641 cgcctcgctg gtagcaatca gtgatgatct tttcaaaaac agaaagattt gtgcacgggt
    23701 tgaacaggtc agcagccgtt acggcgtaac tattaaaatt tgtacttgtg atttgcatca
    23761 gaccaacaga atagcgacga ccttttgcct ctatctgttt gacgatgctt aatgcatcct
    23821 ccttagtttt tggcatatgt gagataaagc ccttgtcgcc tggctggcgt tcacgtttgg
    23881 ggatgatctc agcaatagcg tagggattaa aaccagactc gacccgcgca acatccagtg
    23941 atgtggaggg gtgaactgtg gcggcacact gcatagccac cgccataaat gaaacggtgg
    24001 aaagcatagt accctcgcta aattagtttc cttgtggggc gtcttcttta ggttcgagta
    24061 gtaccagctt gccggaaaca gcaataccag gaacgagcat aatattcagt cctggttttc
    24121 cgttatgcgc gaatgccgcg ccaaccttgg tccagtaggt atttttaccg ccgttttcgt
    24181 cagtgggaac ttcctgtgtg acgtatacgt tataggtggg tttgggcatt tatttatcct
    24241 cttttgacat tagctctttc aacatttcgt tgtgagcttc attacttaat ttgtcgatca
    24301 tgtactgcaa aaaggcactt ggacgaatat ttacctccgc aacataactt atatctctgg
    24361 cgtgttttgc cagtgtttca tagcgttttt tgccgatgta aat
//
