LOCUS       NZ_CP139952            18744 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Escherichia coli strain Nord1 plasmid pNORD1_3.
ACCESSION   NZ_CP139952
VERSION     NZ_CP139952.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38610602
            Assembly: GCF_034424275.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18744)
  AUTHORS   Braun,S.D.
  TITLE     DRESI Project
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18744)
  AUTHORS   Braun,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2023) Optical Molecular Diagnostics and System
            Technology, Leibniz Institute of Photonic Technology, Albert
            Einstein Strasse 9, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-SEP-2020
            Assembly Method                   :: Flye v. 2.8.1-b1684
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 199.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 12:30:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,403
            CDSs (total)                      :: 5,279
            Genes (coding)                    :: 5,040
            CDSs (with protein)               :: 5,040
            Genes (RNA)                       :: 124
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 239
            CDSs (without protein)            :: 239
            Pseudo Genes (ambiguous residues) :: 0 of 239
            Pseudo Genes (frameshifted)       :: 119 of 239
            Pseudo Genes (incomplete)         :: 133 of 239
            Pseudo Genes (internal stop)      :: 43 of 239
            Pseudo Genes (multiple problems)  :: 54 of 239
            Pseudo Genes (short protein)      :: 3 of 239
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP139952.1.
            Bacteria and source DNA available from Leibniz-IPHT Jena.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Nord1"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pNORD1_3"
                     /geo_loc_name="Germany"
                     /collection_date="2020-05-12"
     gene            <1..>502
                     /locus_tag="U0533_RS00005"
                     /old_locus_tag="U0533_00005"
                     /pseudo=""
     CDS             <1..>502
                     /locus_tag="U0533_RS00005"
                     /old_locus_tag="U0533_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137361.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=2
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /name="conjugal transfer protein TraH"
     gene            <504..2632
                     /gene="traG"
                     /locus_tag="U0533_RS00010"
                     /old_locus_tag="U0533_00010"
                     /pseudo=""
     CDS             <504..2632
                     /gene="traG"
                     /locus_tag="U0533_RS00010"
                     /old_locus_tag="U0533_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating-pair stabilization
                     protein TraG"
                     /name="traG"
     gene            2647..3149
                     /locus_tag="U0533_RS00015"
                     /old_locus_tag="U0533_00015"
                     /pseudo=""
     CDS             2647..3149
                     /locus_tag="U0533_RS00015"
                     /old_locus_tag="U0533_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="surface exclusion protein"
                     /name="surface exclusion protein"
     gene            3181..3912
                     /gene="traT"
                     /locus_tag="U0533_RS00020"
                     /old_locus_tag="U0533_00020"
     CDS             3181..3912
                     /gene="traT"
                     /locus_tag="U0533_RS00020"
                     /old_locus_tag="U0533_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer complement resistance protein
                     TraT"
                     /protein_id="WP_000850422.1"
                     /translation="MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIWL
                     EPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKM
                     DLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVN
                     YTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNANKVNL
                     KFEEAKPVLEDQLAKSIANIL"
                     /name="traT"
     gene            4115..4852
                     /locus_tag="U0533_RS00025"
                     /old_locus_tag="U0533_00025"
     CDS             4115..4852
                     /locus_tag="U0533_RS00025"
                     /old_locus_tag="U0533_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021503363.1"
                     /translation="MTSDNIAEYVGENNQFTEKPVAEYPPVIQDNTVTTKDYLYSNNID
                     TDLLVVIGGLIVILFLMMLIMYFINSLRHKELTEILTKISFPEKSGSNLLKPEAVSCNL
                     LSLCVLAPVFCTPRKLAEVSREIIVASAQEIAWTPGSSRIDGHQGENITWSLSSQSPAD
                     KYDLINKTSRVSPDSGRFYEPDTVLDHRERVRLFIQIQFPHGSDWSEVLRLTDIVTEKV
                     SSGRAAGGYHHRHTGYTWSVSVN"
                     /name="hypothetical protein"
     gene            4903..7146
                     /gene="traD"
                     /locus_tag="U0533_RS00030"
                     /old_locus_tag="U0533_00030"
     CDS             4903..7146
                     /gene="traD"
                     /locus_tag="U0533_RS00030"
                     /old_locus_tag="U0533_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001577029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="WP_327058900.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLIL
                     WVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMIWC
                     GEQLWSAFVLATVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVARML
                     KKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVSTGKSEVIRRLANYARKRGDMVVIYDRS
                     CEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNVANTLIPMGTKEDPFWQGS
                     GRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIEKTAISI
                     RAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHASLKPVVS
                     MWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCYVFGIQSYA
                     QLEDIYGEKAAATLFDVLNTRAFFRSPSHQIAEFAAGEIGEKEHLKASLQYSYGADPVR
                     DGVSTGKEMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQARPKVAPEFIPRD
                     INPEMENRLSAVLAAREAEGRQMASLFEPEVASGEGVTQAEQPQQPQQPQQPQQPQQPQ
                     QPQQPQQPQQPQQPQQPQQPVSSVINDKKSDAGVSVPAGGIEQELKMKPEEEMEQQLPP
                     GISESGEVVDMAAYEAWQQENHPDIQQHMQRREEVNINVHRERGEDVEPGDDF"
                     /name="traD"
     gene            7146..12415
                     /gene="traI"
                     /locus_tag="U0533_RS00035"
                     /old_locus_tag="U0533_00035"
                     /pseudo=""
     CDS             7146..12415
                     /gene="traI"
                     /locus_tag="U0533_RS00035"
                     /old_locus_tag="U0533_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490592.1"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /name="traI"
     gene            12435..13181
                     /gene="traX"
                     /locus_tag="U0533_RS00040"
                     /old_locus_tag="U0533_00040"
     CDS             12435..13181
                     /gene="traX"
                     /locus_tag="U0533_RS00040"
                     /old_locus_tag="U0533_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="WP_016230917.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWFQSFLVWSPGQRDIIKTVALVLMV
                     LDHINLIFQLKQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQFAY
                     YLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAGLLM
                     LAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKS
                     LPRFWPGDFFPVFYACHLAVLGVLAL"
                     /name="traX"
     gene            13236..13796
                     /locus_tag="U0533_RS00045"
                     /old_locus_tag="U0533_00045"
     CDS             13236..13796
                     /locus_tag="U0533_RS00045"
                     /old_locus_tag="U0533_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="WP_097431173.1"
                     /translation="MTEQKRPVLTLKRKTEGETPVRRRKTIINVTTPPKWKVKKQKLAE
                     KAAREAELAAKKAQARQALSIYLNLPSLDEAVNTLKPWWPGLFDGDTPRLLACGIRDVL
                     LEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGTCRYDTEGYVTEHISQEEEAYAA
                     ARLDKIRRQNRTKAELQAVLDEK"
                     /name="fertility inhibition protein FinO"
     gene            13929..14141
                     /locus_tag="U0533_RS00050"
                     /old_locus_tag="U0533_00050"
     CDS             13929..14141
                     /locus_tag="U0533_RS00050"
                     /old_locus_tag="U0533_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="WP_052983100.1"
                     /translation="MNGFRNSSRNGQVWRYQRAGSRAVILEVSGRWMEAAEAWRRAAGV
                     APRTDWQQFARKRAAHCHRRCRGRV"
                     /name="ANR family transcriptional regulator"
     gene            14386..14847
                     /locus_tag="U0533_RS00055"
                     /old_locus_tag="U0533_00055"
     CDS             14386..14847
                     /locus_tag="U0533_RS00055"
                     /old_locus_tag="U0533_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_123005656.1"
                     /translation="MRKYIPLVLFIFSWPVLSADIHGRVIRVLDGDTIEVMDSRKAVRI
                     RLVNIDAPEKKQDYGRWSTDMMKSLVAGKTVTVTYFQRDRYGRILGQVYAPDGMNVNQF
                     MVRAGAAWVYEKYNTDPVLPVLQNEARQQKRGLWSDADPVPPWIWRHRK"
                     /name="thermonuclease family protein"
     gene            14893..15102
                     /gene="hha"
                     /locus_tag="U0533_RS00060"
                     /old_locus_tag="U0533_00060"
     CDS             14893..15102
                     /gene="hha"
                     /locus_tag="U0533_RS00060"
                     /old_locus_tag="U0533_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_001298565.1"
                     /translation="MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAAD
                     HRLAELITGKLYDRIPKEIWKYVR"
                     /name="hha"
     gene            15140..15730
                     /locus_tag="U0533_RS00065"
                     /old_locus_tag="U0533_00065"
     CDS             15140..15730
                     /locus_tag="U0533_RS00065"
                     /old_locus_tag="U0533_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_097431171.1"
                     /translation="MKLIIFILIVLIIAALLIRIILKSVNQHSPLLMQLHAAGIRTGDA
                     ERILSGGEYWQRQKTLLTEREVSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRPRS
                     RQWWQLFRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQAGI
                     PLLRSHDARKLLQMTGEWLNATGADQQSPEHRS"
                     /name="DUF2726 domain-containing protein"
     gene            15885..16358
                     /locus_tag="U0533_RS00070"
                     /old_locus_tag="U0533_00070"
     CDS             15885..16358
                     /locus_tag="U0533_RS00070"
                     /old_locus_tag="U0533_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_016240489.1"
                     /translation="MKYDDVSELMIKREHNILIVGNSASHIDKFFKGYSIPGSKYYDFT
                     QINSDSDVERNEDAVSFIRDAMNSEEQTIIFNCAGWPDLGGGSAVSQFAMMVRKFGKQL
                     IVAVSEKDAIKLKDNFDIIGMLSYGKENFIAMSHTKNELTGGKRRYRIKNGCK"
                     /name="hypothetical protein"
     gene            16605..16754
                     /locus_tag="U0533_RS00075"
                     /old_locus_tag="U0533_00075"
     CDS             16605..16754
                     /locus_tag="U0533_RS00075"
                     /old_locus_tag="U0533_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_001312851.1"
                     /translation="MTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLAY
                     EARK"
                     /name="Hok/Gef family protein"
     gene            17039..17287
                     /locus_tag="U0533_RS00080"
                     /old_locus_tag="U0533_00080"
     CDS             17039..17287
                     /locus_tag="U0533_RS00080"
                     /old_locus_tag="U0533_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="WP_000083839.1"
                     /translation="MSQTENAVTSSSGTKRAYRKGNPLTLAERQQASLARKRATHKELR
                     VFIPAALKAQLQVMCEAEGVTQAEMIAELIKQKSAFS"
                     /name="replication regulatory protein RepA"
     gene            17532..17606
                     /gene="tap"
                     /locus_tag="U0533_RS00085"
                     /old_locus_tag="U0533_00085"
     CDS             17532..17606
                     /gene="tap"
                     /locus_tag="U0533_RS00085"
                     /old_locus_tag="U0533_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="WP_001365705.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
                     /name="tap"
     gene            17599..18456
                     /gene="repA"
                     /locus_tag="U0533_RS00090"
                     /old_locus_tag="U0533_00090"
     CDS             17599..18456
                     /gene="repA"
                     /locus_tag="U0533_RS00090"
                     /old_locus_tag="U0533_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator RepA"
                     /protein_id="WP_123005655.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRF
                     DFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLA
                     TESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDVSEE
                     AVAAARRSRVVWENKQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARA
                     RRDADRERQDIVTLVKRQLTREIAEGRFSASREAVKREVERRVKERMILSRNRNYSRLA
                     TASP"
                     /name="repA"
     Typing          17630..18456
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.43"
                     /coverage="97.0"
                     /evalue="0.0"
     Typing          7224..12412
                     /name="MOBF"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.879"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4904..7143
                     /name="MPF_Unknown"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="95.333"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcatcaatat ttttgccggc gcgttaccac tggccgcgat atcctccggg cgattatgga
       61 gggggaacgg caaaaagttt atcactgcaa cgattcggac aagtgtctga aggtggtggc
      121 ggatgcaaat gtgaccatcg cccgggataa agccctgaaa tcacagatta caaaactgct
      181 caccagtatt cagaataaag cggtgagtga tactccactg gatgacaggg aaaaaggctt
      241 catttccagc accaccgtcc ccgtctttaa atatcttatt gacccgcaga tgctcggtgt
      301 atccagcagc gtggtttacc atgacgggct acgacatcat gctccagtac attcaggaac
      361 tgcttcagca ggcccgggcc atgatgccac cgggaactat ccacagaccg tgctggacag
      421 tgtgctggag aacagggggc aggtaaaggt ccagcaggat gcattgctgg ttgttgaccg
      481 tcagatgagc tatatgcgcc ggtaataata atttcataac ctgtaaagat gcgtcggtcg
      541 gacagctgaa agtcactgaa agacaggctg aatctcgata caaagacggg aggcaagacg
      601 ctccagccag tctgccagtc atattatgcg ccagaacgtc accatgaatg ccctgaaaga
      661 gggtatcacc agtaatgcag cccgtaacgg tgataccgcc agcctggtca gtctggccac
      721 ggcaaatcga tggagaaaca gcgtctggca catgtctcca ttggtcatgt gctgatttga
      781 aacccgcgat ggtgcagacc attctggtgg gcattaccat tggtatcttc ccgctcctgg
      841 tactggcggc tgtcttcagc agactgacgc tgtctgttct gagaggctat gtgtttgctc
      901 tgatgtggtt ccagacctgg ccgttgctgt gtgccattct gaacagtgcc atgacattct
      961 atgcaaagca gaatggtgca ccggtcgtgc tctctgaact ctctcagata cagctgaaat
     1021 actccgacct ggcgtccact gccggatata tatctgtcat gatacccccg ttgtcatgga
     1081 tgatggtaaa aggccttggc gcaggttttt ccagcgtgta cagccatttc gcttcctctg
     1141 ctatcagccc gactgccagt gcggcaggta gtgtggttga cggtaattac tcctacggca
     1201 acatgcagac ggaaaacgtg aacggcttca gctggagcac caacagcacc acgtcgtttg
     1261 gtcagatgat gtaccagacc ggcagtggcg caactgccac acagacccgt gacggtaata
     1321 tggtgatgga tgcgagcggg gcgatgtccc ggttaccggt cggcatcaat gcaacgcgtc
     1381 agattgcggc ggcacaacag gaaatggccc gggaggcgtc gaacagagca gaaagcgccc
     1441 tgcatgggtt cagcagcagt attgccagtg cccggaactc gctcagtcag tttggttcta
     1501 accggggagc agtgattctg tcaccggtgg tgctgacagc acgatgagcg cacaggactc
     1561 catgatggcc agccgtatgc gcagcgcagt ggaaagctat gcgaaggcgc ataatatcag
     1621 taatgagcag gcgacaagag aactggcatc aagaagtacg agaggttctg cggggatgta
     1681 tggcgatgct catgctgaat ggggggttaa acctaaaatt cttggtgttg gtggtggcgt
     1741 aggtgttaga ggtggtggtc gggcaagtat tgactggagt gatgaggatg cgcatcaggc
     1801 cagcagtggt tcacgggcca gcaatgatgc tcgtcatgat atcgatgcca gagctacaca
     1861 agactttaaa gaggccagcg attactttac cagtcgcaaa gtcagtgagt ccggcagcca
     1921 tactgacaat aatgctgatt cccgtgtgga tcagttgtct gcagccctga attcagcgaa
     1981 gcagagttac gaccagtaca cgacgaatat gactcgcagc catgaatatg ctgaaatggc
     2041 atcccgtact gaaagcatga gtgggcagat gagtgaagac ctgtcgcaac agtttgcaca
     2101 gtatgtgatg aaacacgccc cgcaggatgc cgaagctatt ctgacaaaca ccagttcacc
     2161 ggagattgca gaacgccgtc gggctatggc gtggtctttt gttcaggaac aggtgcagcc
     2221 tggtgttgat aatgcctggc gtgaatcccg tggggacatc ggtaaaggaa tggagagcgt
     2281 accttcgggt ggtggcagcc aggatattat tgctgatcat caggggcatc aggccattat
     2341 tgagcaaaga acgcaggaca gtaatatccg taatgatgta aaacatcagg ttgataatat
     2401 ggtcacagaa taccgaggca atatcggaga tactcagagc agcatacgtg gcgaagaaaa
     2461 tattgtagga agacagtatt ctgaactaca aaatcaccat aaaacagagg cattatctca
     2521 gaataataaa tataatgaag agaaatcggg tcaggaaaga atgcccgggg ctgacagtcc
     2581 acaggaactg atgaaaagag caaaggagta tcaggataag cacaagcaat aatattgtat
     2641 ggggagatga taatgaaaaa tttagctcat attgctctgg tgacggtgat acagttcatt
     2701 gcctgttatc tggctgattg gggagtgccg aaacagtttt tatcctgtgc tttattgtac
     2761 tatggcaggg attgtttata tggttatttt ctcaaatacg aaaaaaacgg catgtgtcgg
     2821 atgagtttaa attcagtaaa ggcgtttggt atatactgat gccagtatct tccttactct
     2881 ctccgttatt aagcctgatg gtttttatca ttggtacact atacgaatta aggcgaatta
     2941 gtggttgtgt aagtgtaaga gaatggatgc aatctcaggt aaatgaacaa actaatgaag
     3001 atttgcatct ggattttgat gatgtgaatt ttgattatgt ggatttttat cgtactaatc
     3061 cagcaacagg attagctatg catggaggat ttgattcagc aggaaatact tttgggactt
     3121 gttggcagga ctatgatgac aggcgataag aaaactgtgg tttgtaaaaa aggtaatttg
     3181 atgaaaacaa aaaaattgat gatggttgca ctggtcagtt ccactctggc cctttcaggg
     3241 tgtggtgcga tgagcacagc aatcaagaag cgtaaccttg aggtgaagac tcagatgagt
     3301 gagaccatct ggcttgaacc cgccagcgaa cgcacggtat ttctgcagat caaaaacacg
     3361 tctgataaag acatgagtgg gctgcagggc aaaattgctg atgctgtgaa agcaaaagga
     3421 tatcaggtgg tgacttctcc ggataaagcc tactactgga ttcaggcgaa tgtgctgaag
     3481 gccgataaga tggatctgcg ggagtctcag ggatggctga accgtggtta tgaaggcgca
     3541 gctgttggtg cagcgttagg tgccggtatt accggatata actcaaattc tgccggtgcc
     3601 acactcggtg tgggccttgc tgccggtctg gtgggtatgg ctgcagatgc gatggtggaa
     3661 gatgtgaact ataccatgat cacggatgtg cagattgcag agcgtactaa ggcaacggtg
     3721 acaacggata atgttgccgc cctgcgtcag ggcacatcag gtgcgaaaat tcagaccagt
     3781 actgaaacag gtaaccagca taaataccag acccgtgtgg tctcaaatgc gaacaaggtt
     3841 aacctgaaat ttgaagaggc gaagcctgtt ctcgaagacc agctggccaa atcaatcgca
     3901 aatattctct gaacctcgtc aggaggctga tctgaccggc ctccttgctg acgcctcgcg
     3961 ttgctcgttg tccaaccccg ggatgtaaca aaataaattt tgtcacctcc cggcgtttcc
     4021 gaaataaata tgaaaacact gagcggttgt gcaaattctt tgtgcgaccg tgaagtgttg
     4081 ccggcgaagc cgggatcttc cggagaaagt cattatgaca tcagacaata tcgctgaata
     4141 tgttggtgag aataatcaat ttactgagaa gcctgtagct gaataccccc cggtgataca
     4201 ggataataca gtgaccacta aagactatct gtacagcaat aatattgata ctgacctttt
     4261 agtggttatc ggagggctta ttgttatatt gtttctcatg atgcttatca tgtactttat
     4321 taattctctc aggcataagg aattaactga aatactgaca aaaatatctt ttcctgaaaa
     4381 atccgggagc aatttgctta aaccggaggc ggtcagctgt aatttgttgt ccctgtgtgt
     4441 gctggcaccg gtattctgta cacccagaaa gctggctgaa gtttccaggg agatcatcgt
     4501 ggcgagtgcg caggaaattg catggacgcc ggggagcagt cgtattgatg gtcatcaggg
     4561 cgaaaatatt acctggtctc tgtcatcgca gtctcctgcc gataagtatg atctcatcaa
     4621 taaaacgtcc cgtgtttctc ctgacagtgg ccgtttttat gaaccggaca cagttctgga
     4681 tcaccgtgaa cgggtacgcc tttttattca gatccagttt ccgcacggga gtgactggtc
     4741 tgaagtattg cgcctgactg atattgttac agagaaggtc tcttccggca gggctgcagg
     4801 cgggtatcac caccggcata cagggtacac ctggtctgtt tctgtgaatt aaccccacat
     4861 catccttttc tgccctgttc cagattttcc cggagtttca tcatgagttt taacgcaaag
     4921 gatatgaccc agggcggtca gattgcgtcc atgcgtatcc gcatgttcag ccagatcgcc
     4981 aatatcatgc tttactgcct gtttattttt ttctggatac tcgttggcct gattttatgg
     5041 gtaaaaataa gctggcagac gtttgtgaac ggctgtattt actggtggtg taccacgctg
     5101 gaaggcatgc gggatttaat caagtcccag ccggtctatg agatccagta ttacggcaaa
     5161 accttccgga tgaacgctgc tcaggtactg catgataaat atatgatctg gtgcggagag
     5221 cagctatggt ccgcattcgt tctggctaca gttgtggcac tggttatttg cctgattacc
     5281 ttctttgttg tctcctggat tctggggcgt cagggtaaac aacagagcga aaatgaagtc
     5341 acaggtggtc gtcagctgac agacaatccg aaagacgttg cccggatgct gaaaaaagac
     5401 ggcaaggact ccgatatccg gattggcgat ctgccgatta tccgggattc cgaaatccag
     5461 aacttctgtc tgcacggaac agtgtcgacg ggtaagtcag aggttattcg acgtcttgcc
     5521 aactatgccc gtaaacgtgg cgacatggtg gtgatttatg accgttcgtg tgagtttgtt
     5581 aaaagttact atgatccctc catcgataag atcctgaatc cgctggatgc ccgctgtgcc
     5641 gcctgggatt tgtggaagga gtgcctgaca cagccggatt ttgataatgt cgcgaacacg
     5701 ctgatcccga tgggaacgaa agaggacccg ttctggcagg gatcaggacg taccattttt
     5761 gcggaagcgg cgtatctgat gcgtaatgac cccaaccgca gctacagcaa actggtggac
     5821 acactgcttt ccatcaaaat cgaaaaactg cgtaccttcc tgcgtaattc accggcggcc
     5881 aacctggtgg aagagaaaat tgagaaaacg gcgatttcca tccgtgctgt gctgaccaac
     5941 tacgtgaaag ccatccgtta cctgcagggg attgagcata acggtgaacc cttcaccata
     6001 cgtgactgga tgcggggtgt ccgggaagat cagaaaaacg gctggctgtt tatctcgtca
     6061 aatgccgaca ctcatgcctc cctgaagccg gtggtttcca tgtggctgtc cattgccatt
     6121 cgtggtctgc tggcaatggg agaaaaccgt aaccgtcgtg tgtggttttt ctgtgatgag
     6181 ttacccacgt tacacaaact gccggacctg gtggagatcc tgccggaagc ccgtaagttc
     6241 ggaggctgtt atgtgtttgg tatccagtcc tatgcccagc tggaagatat ctacggtgag
     6301 aaagcggcgg ccacgctgtt tgatgtgctg aatacccgtg cctttttccg ctccccgagc
     6361 catcagattg cagagtttgc tgccggtgaa attggtgaga aagagcacct gaaagccagt
     6421 ctgcagtatt cctacggtgc tgaccccgtg cgtgacgggg tatcgaccgg taaggagatg
     6481 gagcgccaga cgctggtcag ttattccgac attcagtctc tgccggatct gacctgctat
     6541 gtcactctgc ccggaccgta tccggcagta aaactctctc tgaaatatca ggcacgaccg
     6601 aaggtcgctc cggagtttat tccgcgtgac atcaacccgg aaatggagaa ccgtctgagt
     6661 gccgtacttg ctgcaaggga agcagaaggt cgccagatgg ccagcctctt cgaaccggag
     6721 gttgcctccg gagaaggcgt gactcaggct gaacagccac aacagccaca acagccacaa
     6781 cagccacaac agccacaaca gccacaacag ccacaacagc cacaacagcc acaacagcca
     6841 caacagccac aacagccaca acagccagtg tcttctgtca tcaatgataa gaagtcagat
     6901 gcaggtgtga gtgttccggc aggggggatc gagcaggagc tgaaaatgaa accggaagaa
     6961 gagatggaac agcaactgcc acccgggatc agtgaatccg gtgaagtggt ggatatggcc
     7021 gcttatgagg catggcaaca ggaaaatcat ccggacatcc agcagcatat gcagcgtcgt
     7081 gaagaggtga acattaatgt gcaccgggag cgcggggagg atgttgagcc gggagatgat
     7141 ttctgatgtt gagtttcagc gttgttaaat cggcaggcag tgccggaaac tattacaccg
     7201 acaaggataa ttactatgtg ctgggcagca tgggagaacg ctgggccggt caggggctga
     7261 acagcttggg ctgcagggca gcgtcgataa ggatgttttt acccgtcttc tggagggcag
     7321 gctgccggac ggggcggatt taagccgcat gcaggatggc agtaataagc atcgtcccgg
     7381 ctacgacctg accttctccg cccccaaaag tgtctccatg atggccatgc tcggggggga
     7441 taaacgtctt attgatgcac ataaccaggc cgtggatttt gctgtccgtc aggtggaggc
     7501 gctggcttcc acacgggtga tgacggacgg acagtcagaa acggtgctga ccggtaatct
     7561 ggtgatggca ctgtttaacc atgacaccag tcgcgatcag gacccacagt tacacacgca
     7621 tgtggtggtg gctaatgtca cgcagcataa cggcgagtgg aagacactga gcagtgacaa
     7681 agtggggaaa accggatttt ccgagaacgt gctcgcgaac cggattgcgt tcgggaaaat
     7741 atatcagagt gagttacgtc agcgcgttga ggcgctgggt tatgaaaccg aagtggtcgg
     7801 taagcacggt atgtgggaga tgccgggcgt accggtggag gccttttcca gtcgttcaca
     7861 ggctatcagg gaggccgtcg gtgaagacgc ctcgctgaaa tcccgggatg tggcggcact
     7921 ggatacgcga aaatccaaac agcacgtcga tccggaaatc agaatggctg aatggatgca
     7981 gacgctgaag gaaaccgggt tcgacatccg ggcatatcgt gacgcggcgg atcagcgtgc
     8041 ggagatccgc acgcaggcgc ccgggcctgc ttcacaggac gggccggatg tgcagcaggc
     8101 ggtgacacag gcgattgccg gattaagtga acgaaaagtg cagttcacgt atacggacgt
     8161 gctggccagg acggtcggca tactgccgcc ggaaaatggt gtgattgaac gggcacgcgc
     8221 cggtatcgat gaggccatca gccgtgagca gcttatcccc ctcgaccgtg agaaggggct
     8281 gttcacatca ggaattcatg tgctcgatga gctgtccgtc cgggcactca gtcgtgacat
     8341 catgaaacag aaccgggtga ccgtacatcc ggagaaaagt gtcccccgga cggctggtta
     8401 cagcgatgcg gtcagtgttc tggcacagga ccgtccgtcg ctggccattg tgtccgggca
     8461 gggcggtgca gccgggcagc gtgagcgggt ggctgaactg gtcatgatgg cccgggagca
     8521 ggggcgggag gtgcagatta tcgctgctga ccgtcgctcg cagatgaacc tgaagcagga
     8581 tgaacggctg tccggtgagc tgataaccgg acgtcgtcag ctgcaggagg gcatggtctt
     8641 cacgccgggc agtactgtta tcgtcgacca gggtgaaaaa ctctccctga aagagacgtt
     8701 aaccctgctg gatggtgccg cacgtcataa cgtacaggtc ctgataaccg acagcgggca
     8761 gcgaaccggt acaggcagtg cgctgatggc catgaaggat gccggggtga acacgtatcg
     8821 ctggcagggc ggagaacagc gaccggcaac catcatcagt gaaccggacc ggaatgtccg
     8881 ctatgaccgg ctggccggag attttgcggc cagcgtgaaa gccggagaag agagcgtggc
     8941 acaggtcagc ggggtacggg aacaggccat actgacacag gccattcgca gtgagctgaa
     9001 aacacagggc gtgctcggac acccggaggt gaccatgacc gccctgtcac cggtctggct
     9061 ggacagccgg agccgttatc tgcgggatat gtaccgaccg gggatggtga tggagcagtg
     9121 gaacccggag acacgcagtc atgaccgcta tgtgatagac cgggtgacag cgcagagtca
     9181 cagcctgacc ctgcgggatg cgcagggcga aacgcaggtg gtgcgtattt cctccctgga
     9241 cagcagctgg tcgctgttcc ggccggaaaa aatgccggtg gcagacggcg agcgactgag
     9301 ggtgacaggg aaaattcccg gactccgcgt ctccggcggt gaccgcctgc aggtggcatc
     9361 cgtcagtgaa gatgcgatga cggttgttgt gccggggcgg gctgaaccgg ccaccctgcc
     9421 tgtggctgat tcaccgttca cggcactgaa gctggagaac ggctgggtgg aaacgcccgg
     9481 gcattccgtc agcgacagtg cgaaggtttt tgcctccgtc acacagatgg cgatggacaa
     9541 cgccacactg aacggtctgg cccgcagcgg tcgtgatgtc cggctgtatt cctcgctgga
     9601 tgaaacccgt actgcggaaa aacttgcccg ccatccctcc tttacggtgg tttctgagca
     9661 gataaaggcg cgtgccggtg agacattgct ggaaaccgct atcagtctgc agaaagccgg
     9721 gcttcacacg ccggcacagc aggccattca tctggccctt cctgtgctgg aaagtaaaaa
     9781 cctggccttc agcatggtgg acctgctgac agaggcgaag tcgtttgctg cagaaggaac
     9841 cggttttact gaactgggag gggaaatcaa tgcgcagata aaacgcggtg acttactgta
     9901 tgtggatgtg gcaaaaggct atggcacagg tctgctggtt tcccgtgcgt cgtatgaggc
     9961 agaaaagagc attcttcgcc atattctcga aggcaaggag gcggtcacgc cgctgatgga
    10021 gagagtaccc ggcgaactca tggagacgtt aacgtcggga cagcgtgccg ccacccgtat
    10081 gatactggaa acgtccgacc gtttcacggt ggtacagggg tatgccggtg tgggtaagac
    10141 cactcagttc cgggcggtga tgtcagccgt gaacatgctg ccggagagtg agcgtccccg
    10201 ggttgtgggg ctggggccca cgcaccgtgc ggtcggtgag atgcgcagcg ccggcgtgga
    10261 tgcacagaca ctggcgtcct ttctgcatga cacgcagctg cagcagcgca gcggagaaac
    10321 gccggatttc agcaacacgc tgtttctgct cgatgagagc tcaatggtgg gcaataccga
    10381 catggcacgg gcatacgccc tgattgcggc cggtggcggt cgtgctgtgg ccagcggtga
    10441 cacggaccag ctgcaggcca tcgcgcccgg tcagcctttc cgtctccagc agacgcgcag
    10501 tgctgccgat gtggccatca tgaaggagat tgtgcgtcag acgccggaac tgcgggaggc
    10561 ggtatacagc ctgattaacc gggatgtgga aagggcactg tccgggcttg agagtgtgaa
    10621 accgtctcag gtgccacgtc tggagggcgc atgggcaccg gagcactccg tgacggagtt
    10681 cagtcacagc caggaagcga aactggcaga agcgcagcag aaggcgatgc tgaaaggcga
    10741 ggctttcccg gatatcccca tgacactgta tgaggccatt gtccgcgact ataccggcag
    10801 gacaccggaa gcacgggagc agacgctgat tgtcacgcac ctgaatgagg accggcgcgt
    10861 actgaacagc atgattcatg atgcacggga aaaggccggt gagctgggca aagagcaggt
    10921 catggtgcct gtcctgaaca cagcgaatat acgtgacgga gaactgcgtc gtctctccac
    10981 ctgggagaaa aacccggatg cccttgccct ggtggatagt gtgtatcacc ggattgccgg
    11041 tatcagcaag gatgacgggc tgataaccct gcaggatgcg gaaggtaaca cgcggctgat
    11101 ttcgccccgg gaggcggtgg ctgaaggtgt cacactgtac acaccagaca aaatccgggt
    11161 ggggaccggt gaccggatgc gcttcacgaa gagtgaccgg gagcgcggtt atgtggccaa
    11221 cagcgtctgg acggtgacag cggtttccgg tgacagtgtc acgctatcgg acggacagca
    11281 gacccgggtg attcgccccg gccaggagcg ggcagagcaa catattgacc tggcctatgc
    11341 catcactgcc cacggtgcgc agggggcgag tgaaaccttt gccatcgcgc ttgaaggcac
    11401 ggaaggtaac cggaaacaga tggccggctt tgagtcagcc tacgtggccc tgtcgcgtat
    11461 gaagcagcat gtgcaggtgt acaccgataa ccgtcagggc tggacggatg ccatcaacaa
    11521 tgccgtacag aaaggaacgg cccacgatgt gtttgaaccg aaaccggacc gggaggtcat
    11581 gaatgcagag cggctgttca gtacggcacg ggaactgcgg gacgtggcgg caggccgtgc
    11641 cgttctccgt caggcagggc tggccggggg agacagccct gcacggttta ttgcaccggg
    11701 acgtaaatat ccgcagccgt atgtggcact gccggcgttt gaccgtaacg gcaagtccgc
    11761 cggtatctgg ctgaacccac tgaccacgga tgacggaaac gggctgcggg gattcagcgg
    11821 tgaaggacgg gtgaaaggca gcggggatgc gcagttcgtg gccctgcagg gcagccgtaa
    11881 cggagagagc ctgctggctg ataatatgca ggatggtgtc cggattgccc gtgataatcc
    11941 tgacagcggt gtggtggtaa gaattgccgg tgaaggtcgt ccgtggaatc ccggtgccat
    12001 caccggtggt cgcgtgtggg gggatatccc ggacagcagc gtccagccgg gagccggaaa
    12061 tggcgaaccg gtcacggcag aggtgctggc acagcggcag gctgaagagg ccatccgccg
    12121 tgaaacggaa cgccgtgcag atgaaattgt ccgtaaaatg gcagagaaca aacctgacct
    12181 gccggatggc aaaacagagc aggctgtcag ggaaattgcc gggcaggagc gtgaccgggc
    12241 tgacataact gaacgggaag ccgcgctgcc ggagagtgtg ctgcgtgaat cacaacggga
    12301 gcaggaagcg gtccgggagg ttgcccggga aaatctgctg caggagcgtc tgcagcagat
    12361 ggagcgggat atggtccgtg acctgcagaa agagaaaacc ctgggcggag actgatacag
    12421 gaagacaaac actgatgaca acggataaca cgaacacgac acgtaacgat tcactggctg
    12481 cacggaccga tacctggttt cagtcatttc tggtctggtc acccggacag cgggatatca
    12541 tcaaaacggt ggcactggtg ctgatggtac tggaccacat caatctgata ttccagctga
    12601 agcaggaatg gatgtttctg gccgggcgag gagcctttcc gctgtttgcc ctggtgtggg
    12661 ggctgaatct gtcccgtcat gcgcatatcc ggcaaccggc cattaaccgg ctgtggggat
    12721 gggggattat tgcccagttc gcatattatc tggcaggctt tccctggtat gaggggaata
    12781 tcctgtttgc ctttgcagtg gcggcacagg tgctgacgtg gtgtgaaacg cgcagtgggt
    12841 ggcgtacagc agcggccatt cttctgatgg ccctgtgggg gcctttgtcc ggcaccagtt
    12901 acggcattgc cgggctgctg atgctggcag tcagccaccg gctgtaccgg gcggaagaca
    12961 gagcggaacg tctggcgctg gtcgcctgtc tgctggctgt tattccggcg cttaaccttg
    13021 ccaccagtga tgcagcggcg gtggctggtc ttgtgatgac ggtgctgacc gttggtctgg
    13081 tgtcgtgtgc aggaaaatca ttaccccgtt tctggcccgg ggattttttc ccggtattct
    13141 acgcctgtca tctggctgtg ctgggcgttc tggcgctgtg acgggtgtgg tatctttgac
    13201 cgtaacagga tgattcgtca gaggcagaac acagcatgac agagcagaag cgaccggtac
    13261 tgacactgaa gcgaaaaacg gaaggggaga cgcctgtccg caggcggaaa accatcatca
    13321 atgtcaccac gccaccaaag tggaaggtga aaaagcagaa gctggccgag aaagcagccc
    13381 gggaagcgga gctggcggca aaaaaagcgc aggccagaca ggcgctgtcc atttatctga
    13441 acctgccctc gctggatgag gccgtgaaca ccctgaaacc ctggtggccg ggattatttg
    13501 acggtgacac accccggctt ctggcctgcg gtatccggga cgtgttactg gaagacgtgg
    13561 cgcagcggaa tatcccgctc tcgcataaaa aactgcgcag ggcgctgaag gccatcaccc
    13621 gttcagaaag ctatctgtgt gccatgaaag ccggtacctg ccggtatgac acggaagggt
    13681 atgtgacgga gcatatttct caggaggagg aggcgtatgc ggcagcgcgt ctggataaaa
    13741 tccgccgcca gaaccggaca aaggcagaac ttcaggccgt gcttgatgag aaataaaaaa
    13801 aagcctccat cagagagagg aggcagggaa ataaggctta aaaggaaata acttccgtac
    13861 ccgaaaggaa gccagtccac tgaattattt accacaataa tactgacgac taaagggggg
    13921 acaggaaaat gaatggattc agaaacagtt cacggaacgg ccaggtctgg cgttaccagc
    13981 gtgccggaag ccgggccgtt attctggagg tcagtggacg ctggatggaa gcggcagaag
    14041 catggcgacg ggctgcaggt gttgcgcccc ggacagactg gcagcagttt gcccgaaaaa
    14101 gggctgcaca ctgccaccgg cgctgccggg gaagggtgta acgaaaaaag cagccttcat
    14161 tactccaggg attcagaagg ctgaataatg catgagattt acttttttaa tctccggtcg
    14221 ggcagtatga ccggacagtt ctgagtagca cagagttttt tccgtattaa gtcgtgattt
    14281 tatattttgt gattaatttc aaaaaataag gtgttattca gtgtgtgctg cgatattcag
    14341 gattacctga aatacaggtg ccatttatct gatatggaga ataacatgag gaaatatatt
    14401 ccactggtat tatttatctt ttcatggccg gtattgtctg cagatattca tggacgggtt
    14461 attcgtgtac tggacggtga taccatcgag gtaatggact cacggaaggc agtgcggatc
    14521 aggctggtaa atattgatgc accggaaaag aaacaggatt atggccggtg gtcaacggac
    14581 atgatgaaat cactggttgc aggaaaaacg gttaccgtca catattttca gcgagatcgt
    14641 tatggtcgta ttctcgggca ggtttatgca ccagacggaa tgaatgttaa tcagtttatg
    14701 gtccgggccg gggctgcctg ggtatatgag aagtacaaca cagatcccgt gctgcctgtc
    14761 cttcagaacg aagccagaca acaaaaacgt gggctctggt cagatgctga tccggttccc
    14821 ccctggatat ggagacaccg taaataaagc gatggcaatc ttatcattca tctgttctca
    14881 gcgggaataa aaatggcaaa aacaaaacag gaatggctgt atcagttacg gcgatgttca
    14941 tcagtcaata cgctggaaaa aattattcat aaaaacagag acagtttatt aaacagtgaa
    15001 cgtgaatcat ttaattcagc agcagaccac cggttagcgg aattaatcac cggaaagtta
    15061 tatgacagga taccaaaaga gatatggaaa tatgtaaggt aataattcag aataattaat
    15121 taccaggagc agataaacaa tgaagctgat tatttttatt ctcattgttc tgattattgc
    15181 agcgttactt atccggatta tcctcaaaag tgtaaatcag cattctcctt tgctgatgca
    15241 gttgcatgcg gcaggtatac ggaccggtga tgcagagcga atactgtccg gcggtgaata
    15301 ctggcaacgt cagaagacgc tgctgacaga aagggaagtc agttttatga aaggactgtt
    15361 cagaattgtg gatatgaagc ggtggtatct gtgtccgcag gtacgggtcg cggatatcgt
    15421 ccagctgaac gggaatatcc ggccacgatc acgccagtgg tggcagttat tcaggatggt
    15481 gtctcagtgg catgttgatg tggttatcgt tgaacggcgt tcgttcagta ttgttgcagc
    15541 agtagagctg gatgatgcca gccatttacg accggaacgc cggcgccggg atattcttct
    15601 ggaagaggtt ctgaggcagg ctggtattcc gttgctcaga agccacgatg ccagaaaact
    15661 gctgcagatg accggagaat ggctgaatgc aacaggggct gatcagcagt caccggaaca
    15721 tcgtagctga cgccttcgcg ttgctcagtt gtccaacccc ggaaacggga aaaagcaagt
    15781 tttccccgtc cccggcgttt ctgtaataaa aagcgggaaa tggtggtcac agagtaaatt
    15841 ccggaaccac ctgtacccaa actttatata ataatggtga atatatgaaa tatgatgatg
    15901 tatcagaatt gatgattaag cgtgaacaca atattcttat tgttgggaac tctgcctccc
    15961 acattgataa gttttttaag gggtattcta taccaggttc taaatattat gatttcactc
    16021 agattaacag tgattcagat gtagagagaa atgaggatgc tgtctccttt atcagggatg
    16081 caatgaatag tgaagagcag acaatcattt ttaattgtgc tgggtggcct gatttaggtg
    16141 gtggatcagc agtatcacag tttgcaatga tggtcagaaa atttggtaaa caacttattg
    16201 tcgctgtaag tgaaaaggat gccatcaaat taaaagacaa ctttgatatt attgggatgt
    16261 tgtcatatgg taaagaaaat tttattgcca tgagtcatac gaaaaacgag ttaactggag
    16321 gaaaacgtcg gtaccggatt aaaaatggat gtaaataaaa agcatactta ttggctggag
    16381 tgacgccttc gtgcttctgt agtaaaaagc gggcaatgca ggtaatagtc agcaacaggg
    16441 aatgtggtat tatcgcggcg ggtgtctgag cctttctggt tcaggcaaga cgcaggtacc
    16501 agaaatgcaa agaccccact tgttaatcca ttaactcgtg aggtctgcat gaagtacatt
    16561 gcactactga ttgtagcctc ttccttgcag agaggtcaaa gtttatgacg aagtatgccc
    16621 ttatcgggtt gctcgccgtg tgcgccacgg tgttgtgttt ttcactgata ttcagggaac
    16681 ggttatgtga gctgaatatt cacaggggaa atacagtggt gcaggtaact ctggcctacg
    16741 aagcacggaa gtaaactgcc gggcggggac ggaagtcccc gctttccgga agtgtgaggt
    16801 atttcagggg cagacacccg acatgccaga aacagccggt cccgcccggg gccggctccc
    16861 gggttaaggc atttcctgtt ttttcagcca tttcgcaaca aaaatcacat taaacaacag
    16921 taatccccgt tgatttgtgc gccaacacag atcttcgtca caattctcaa gtcgctgatt
    16981 tcaaaaaact gtagtatcct ctgcgaaacg atccctgttt gagtattgag gaggcgagat
    17041 gtcgcagaca gaaaatgcag tgacttcctc atcaggtaca aagcgagcat acagaaaagg
    17101 taatcctctg acgcttgcag aacgtcagca ggcatccctg gcaagaaaac gagctacaca
    17161 taaagaactc agagtgttca ttcctgctgc gttaaaagcg caattgcagg tgatgtgtga
    17221 agctgagggc gttacccagg ctgagatgat tgccgaactg ataaagcaga agagtgcttt
    17281 tagctaacta aaatgtagcg acatcacatt cttgcctgtt tctggtgtgc gtgatagatt
    17341 gctgatcgtt taaggaattt tgtggctggc cacgccgtaa ggtggcaggg aactggttct
    17401 gatgtggatt tacaggagcc agaaaagtga aaaccccgat aatcttcgac aagtttggcg
    17461 actgagaaga ttaccggggc catctaaaaa ccgtatagcc aacaattcag ctatgcgggg
    17521 agtatagtta tatgcccgga aaagttcaag acttctttct gtgctcactc cttctgcgca
    17581 ttgtaagtgc aggatggtgt gactgatctt caacaaacgt attaccgcca ggtaaagaac
    17641 ccgaatccgg tgtttacacc ccgtaaaggt gccggaacgc tgaagttctg cgaaaaactg
    17701 atggaaaagg cggtgggctt cacttcccgt tttgatttcg ccattcatgt ggcgcatgcc
    17761 cgttcgcgtg gtctgcgtcg acgcatgcca ccggtgctgc gtcgacgggc tattgatgcg
    17821 ctcctgcagg ggctgtgttt ccactatgac ccgctggcca accgcgtcca gtgctccatc
    17881 accacgctgg ccattgagtg cggactggcg acggagtctg ctgccggaaa actctccatc
    17941 acccgtgcca cccgggccct gacgttcctg tcagagctgg gactgattac ctaccagacg
    18001 gaatatgacc cgcttatcgg gtgctacatt ccgaccgata tcacgttcac atctgcactg
    18061 tttgctgccc tcgatgtatc agaggaggca gtggccgccg cgcgccgcag ccgtgtggta
    18121 tgggaaaaca aacaacgcaa aaagcagggg ctggataccc tgggcatgga tgaactgata
    18181 gcgaaagcct ggcgttttgt tcgtgagcgt tttcgcagtt atcagacaga gcttaagtcc
    18241 cggggaataa agcgtgcccg tgcgcgtcgt gatgcggaca gggaacgtca ggatattgtc
    18301 accctggtga aacggcagct gacgcgcgaa atcgcggaag ggcgcttctc tgccagtcgt
    18361 gaggcggtaa aacgtgaagt ggagcgtcgt gtgaaggagc gcatgattct gtcacgtaac
    18421 cgcaattaca gccggctggc caccgcttcc ccctgaaagt gacctcctca gaataatccg
    18481 gcctgcgccg gaggaatccg cacgtctgaa gcccgtcagt acagaaaaaa acagcaccac
    18541 atacaaaaaa caacctcatc atccactttc agatgcatcc ggttctctct gtttttgata
    18601 caaaacacgc ctcacagacg gggaattttg cttatccaca ttaaactgca agggacttcc
    18661 ccataaggtt acaaccgttc atgtcataaa gcgccagccg ccagtcttac agggtgcaat
    18721 gtatctttta aacacctgtt tata
//
