LOCUS       NZ_CP139844            24120 bp    DNA     circular CON 21-DEC-2023
DEFINITION  Escherichia coli strain Nord58 plasmid pNORD58_4, complete sequence.
ACCESSION   NZ_CP139844
VERSION     NZ_CP139844.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38610762
            Assembly: GCF_034422435.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24120)
  AUTHORS   Braun,S.D.
  TITLE     DRESI Project
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24120)
  AUTHORS   Braun,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2023) Optical Molecular Diagnostics and System
            Technology, Leibniz Institute of Photonic Technology, Albert
            Einstein Strasse 9, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 17-MAR-2023
            Assembly Method                   :: Flye v. 2.9.1-b1780
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 61.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/21/2023 09:39:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,795
            CDSs (total)                      :: 5,664
            Genes (coding)                    :: 5,273
            CDSs (with protein)               :: 5,273
            Genes (RNA)                       :: 131
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 98
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 391
            CDSs (without protein)            :: 391
            Pseudo Genes (ambiguous residues) :: 0 of 391
            Pseudo Genes (frameshifted)       :: 225 of 391
            Pseudo Genes (incomplete)         :: 194 of 391
            Pseudo Genes (internal stop)      :: 62 of 391
            Pseudo Genes (multiple problems)  :: 78 of 391
            Pseudo Genes (short protein)      :: 3 of 391
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP139844.1.
            Bacteria and source DNA available from Leibniz-IPHT Jena.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24120
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Nord58"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pNORD58_4"
                     /geo_loc_name="Germany"
                     /collection_date="2017-05-12"
     gene            89..3439
                     /gene="traA"
                     /locus_tag="U0535_RS01950"
                     /old_locus_tag="U0535_01950"
     CDS             89..3439
                     /gene="traA"
                     /locus_tag="U0535_RS01950"
                     /old_locus_tag="U0535_01950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020750535.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ti-type conjugative transfer relaxase TraA"
                     /protein_id="WP_111961457.1"
                     /translation="MAIYHLNTHTIGRAAGHSAVAAAAYRSASSLVDERTGEVFDFTRK
                     GGVLSSEIVTPAGVPVPERAALWNAAETAEKRKDARVAREWRAALPHELNEADRKELAT
                     RMGQAIADRYGVAVDVCIHAPDKEGDDRNFHVHMLATTRTIQADGTLGAKAVIELANKD
                     RQKAGIPGTSQGDIIEIRQQWAELTNEALERAGISARVDHRSYADQGVELTPTKHIGSD
                     AVAMDRRGLEADRIDIHNADRQEQARQIVERPEIILDKLTATQAVFTRRDIAAELNRYI
                     DDADQFQGLLARLENSPLLVEMEPANGRDPAKFSTREMIDIERGMVDSAERLARTGRHG
                     VSGPITNAAIDGAGTLSAEQQNAVRHVLKPGSLAVVIGDAGTGKSFSMKVAREAWQAQG
                     FNVRGAALAGKAADELQAGSGIDSRTLASLEFAWKNGKDKLTSRDVLVIDEAGMIGSRQ
                     LGRVLKAAEQAGAKVVLLGDDKQLAAIEAGAAFRGVVQHVGAAEITEVRRQKEAWARAA
                     GQELARGSVADGLAAYAERGHVKIHDSRDAARDSLAAAYVGDQGKGSQIILAHSNKDVQ
                     ALNEAVREARKERGELRGTARFMTERGGREFAPGDRIVFLKNDRDLGVKNGTLGTVERA
                     EDGSLAVRLDSGEARRFQAAQYAAVDHGYAVTIHKAQGVTVDRAYLLATPGMDRSLAYV
                     GMTRHREAATLFAGADDFTDRRAGRLVDHGAAPYENKPENRASYFATLENDNGERHTIW
                     GVDLERAIAASGAKRGDRIGLEHGGSETVRLPDGTTAERNTWHVRGAAELAAGKLAQVL
                     GRERPKESTLDFADRRGFDGESVVRRWLERGRAKVAELAGKMRDGLRRNLERHGRPDLM
                     PATDIAGTPTVQRPQQNERTPEDEKKRRAAEIAAKFRQQVSEERGEQAAPQQRPQAERP
                     APDPLAGFRAGVERAEAAGGGLALDVAKAQLAVAQEFHAAGKDPRHHSAAIMQEGQQRA
                     FAGLAQPSQAKAEPERLAAVQVSEQDRKRAEMNARQEVSRFKTLAAGRRNGIAGYTDRS
                     PSKWQALPGELRERIERFNAMPKERQAVELDKMQRELADRYARNPQEITRSRQQQREQE
                     RGRDGGRGY"
                     /name="traA"
     gene            3525..3914
                     /locus_tag="U0535_RS01955"
                     /old_locus_tag="U0535_01955"
     CDS             3525..3914
                     /locus_tag="U0535_RS01955"
                     /old_locus_tag="U0535_01955"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015670327.1"
                     /translation="MSTEPTNEELAKSYATKIEQAQERREAKDQERLERHGQAAALASQ
                     NIEAEQPQAKQAQGFELDAQNQDSAEQRIDRNEINGQQAKTLAKELNRDNESGDQVKQA
                     RAREIAERFKEKAARDREQSRSFSR"
                     /name="hypothetical protein"
     gene            3987..4205
                     /locus_tag="U0535_RS01960"
                     /old_locus_tag="U0535_01960"
     CDS             3987..4205
                     /locus_tag="U0535_RS01960"
                     /old_locus_tag="U0535_01960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032490922.1"
                     /translation="MATSNVTGRAEPGISKYCITFGVSLAALILAGGVLVFSYWQHVEL
                     LHEGDRVGTRLERLGLIDREGAQHEPR"
                     /name="hypothetical protein"
     gene            4192..4965
                     /locus_tag="U0535_RS01965"
                     /old_locus_tag="U0535_01965"
     CDS             4192..4965
                     /locus_tag="U0535_RS01965"
                     /old_locus_tag="U0535_01965"
                     /inference="COORDINATES: protein motif:HMM:NF024758.3"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]; GO:0008236 - serine-type peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="WP_322471707.1"
                     /translation="MSRAKAWRRAALATYIAAGAALTLAGYTVATTAANANTLRDTRER
                     IEDFQREQTAIAENSISAASVRRGTLPPDTRPPVAPDWPALAERAMPSVVALAGIDKPY
                     GTGQNNHAWRIPGVQQNAATAALTRIRAWHRDWPKEDAKRRQRIICGGVAVEGNKVLTV
                     AHCVEGQEALRVRTAAGEWREARVIGADISRDVALIEIEGDPLPPIPVAGVMPRQGQDV
                     MAIGSPGGYGFAVGVGIVAWYGRDAAMLSPMISCW"
                     /name="serine protease"
     gene            4956..5126
                     /locus_tag="U0535_RS01970"
                     /old_locus_tag="U0535_01970"
     CDS             4956..5126
                     /locus_tag="U0535_RS01970"
                     /old_locus_tag="U0535_01970"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_322471708.1"
                     /translation="MLVTASIIGGNSGGVVVNTRGEAVSLVSYGYGIYTQTVPIDRAQA
                     VAAEIERRVVR"
                     /name="hypothetical protein"
     gene            5222..5560
                     /locus_tag="U0535_RS01975"
                     /old_locus_tag="U0535_01975"
     CDS             5222..5560
                     /locus_tag="U0535_RS01975"
                     /old_locus_tag="U0535_01975"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032490913.1"
                     /translation="MKLRNSFPLAAVAALLIASTAHAGQDADAARFSIMAPVQAAYDAY
                     QVTASRAQNTMDSIEAELREPGLSAERRELLAVSLATLRAREAAALERLHAESALAQLK
                     MADWNASR"
                     /name="hypothetical protein"
     gene            complement(<5709..>5819)
                     /locus_tag="U0535_RS01980"
                     /old_locus_tag="U0535_01980"
                     /pseudo=""
     CDS             complement(<5709..>5819)
                     /locus_tag="U0535_RS01980"
                     /old_locus_tag="U0535_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /name="antitoxin"
     gene            complement(5822..5995)
                     /locus_tag="U0535_RS01985"
                     /old_locus_tag="U0535_01985"
     CDS             complement(5822..5995)
                     /locus_tag="U0535_RS01985"
                     /old_locus_tag="U0535_01985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032490924.1"
                     /translation="MNQAATISAAVPADVKAEAAAVAAAHGMSLAGLVRELVARVAARE
                     AETLAWLDEARR"
                     /name="hypothetical protein"
     gene            complement(5992..6855)
                     /locus_tag="U0535_RS01990"
                     /old_locus_tag="U0535_01990"
     CDS             complement(5992..6855)
                     /locus_tag="U0535_RS01990"
                     /old_locus_tag="U0535_01990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004083633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NgoMIV family type II restriction endonuclease"
                     /protein_id="WP_102661115.1"
                     /translation="MSVPAEFSEARKAFHAKLLEATLTTNAAGVVSNADSSNTTSKAIA
                     KGIADLLKAETIGERIAGQTSGNQFEGICAGFVRETFLKLGHLRPGIWDVHQVSGRNRL
                     EIARYEQYAHLVALDRAAKADAELAAALGSDYTITPDIVVVRDTEDDSAINAPALLVDD
                     SVTTLASLRKKNGGLPLLHASISCKWTIRSDRAQNARSEALNLVRNRKGRLPHVVVVTA
                     EPTPSRLASIALGTGDIDCVYHFALYELQATVEALGMTDAADMLAVMVDGKRLKDISDL
                     PLDLAV"
                     /name="NgoMIV family type II restriction endonuclease"
     gene            complement(6855..7811)
                     /locus_tag="U0535_RS01995"
                     /old_locus_tag="U0535_01995"
     CDS             complement(6855..7811)
                     /locus_tag="U0535_RS01995"
                     /old_locus_tag="U0535_01995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798690.1"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_102661116.1"
                     /translation="MSQFNSLEMCAGAGGQALGLEMAGFDHAALVELEPAACATLRLNR
                     PAWNVIEDDLRRFDGRPYQGIDLLAGGVPCPPFSKAGKQLGAKDERDLFPEAIRLVDEC
                     RPQAVMLENVRGLLDAVFDDYRNKVEKQLKKLGYVPGWRLFNASDYGVSQLRPRVVFVG
                     IRKDLAGGFSWPEPLQSEPLTVGELLHDLMATNGWRGANRWREQANVIAPTLVGGSKKH
                     GGPDLGPTRAKRAWAALGVDGMGLWDDAPPRDFVGMPRLTTRMTARIQGFPDDWQFSGR
                     KTAAYRQIGNAFPPPVAAAVARQIFAALSVKRIYKVA"
                     /name="DNA cytosine methyltransferase"
     gene            complement(8145..8711)
                     /locus_tag="U0535_RS02000"
                     /old_locus_tag="U0535_02000"
     CDS             complement(8145..8711)
                     /locus_tag="U0535_RS02000"
                     /old_locus_tag="U0535_02000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009602860.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_003159185.1"
                     /translation="MALIGYARVSTAEQDTALQTDALRKAGCERVFEDTASGAKADRPG
                     LADALAYLRDGDVLAVWRLDRLGRSMPHLIETIGALEARGVGFRSLTEAIDTTTPGGRL
                     IFHVFGALGQFERDLIRERTKAGLTAAAARGRKGGRKPVVTADKLQRAREHIANGLNVR
                     EAATRLKVSKTALYTALQSTSAADS"
                     /name="recombinase family protein"
     gene            8893..9144
                     /locus_tag="U0535_RS02005"
                     /old_locus_tag="U0535_02005"
     CDS             8893..9144
                     /locus_tag="U0535_RS02005"
                     /old_locus_tag="U0535_02005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019334760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_003108276.1"
                     /translation="MTTLTVTARGQVTFRKDVLQHLGIRPGDKIELDLLPDGRGVLKAA
                     RPAGTIASFVGLLAGKTQKVATIEEINEAAAQGWAGKQ"
                     /name="AbrB/MazE/SpoVT family DNA-binding domain-containing
                     protein"
     gene            9141..9536
                     /locus_tag="U0535_RS02010"
                     /old_locus_tag="U0535_02010"
     CDS             9141..9536
                     /locus_tag="U0535_RS02010"
                     /old_locus_tag="U0535_02010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017172645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_003159186.1"
                     /translation="MKVAVDTNVLVRAVVRDDPAQADVAAAVLTDAELIAVALPCLCEF
                     VWVLLRVYGFQQADAASAIRALLAAANVEVNRPAVEAGLLVLDAGGDFADGVIAYEGNW
                     LGGETFVSFDKKAVALLTAQGQSTRLL"
                     /name="type II toxin-antitoxin system VapC family toxin"
     gene            9548..10084
                     /locus_tag="U0535_RS02015"
                     /old_locus_tag="U0535_02015"
     CDS             9548..10084
                     /locus_tag="U0535_RS02015"
                     /old_locus_tag="U0535_02015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_003159187.1"
                     /translation="MNEFRRLAAKIDQHMQQLAAQGVSEAHAIINRMMGYGPDLHRIWV
                     GTSDQQLMALSREFPGFYRYARIMEEASEAERRKASRPYDGMAEFSEQHKQMGAQLLTT
                     AATLERGYQAFRASGSLQDFRPQLDELGRLHRQWLSDLEAFKDSLRTQGAEPKVLEYVN
                     EAFGRLAERIKQLAG"
                     /name="hypothetical protein"
     gene            complement(10583..11083)
                     /locus_tag="U0535_RS02020"
                     /old_locus_tag="U0535_02020"
     CDS             complement(10583..11083)
                     /locus_tag="U0535_RS02020"
                     /old_locus_tag="U0535_02020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000376623.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGR
                     GVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLE
                     LEI"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(11211..12050)
                     /gene="sul1"
                     /locus_tag="U0535_RS02025"
                     /old_locus_tag="U0535_02025"
     ARG             complement(11215..12050)
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(12044..12391)
                     /locus_tag="U0535_RS02030"
                     /old_locus_tag="U0535_02030"
     CDS             complement(12044..12391)
                     /locus_tag="U0535_RS02030"
                     /old_locus_tag="U0535_02030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            complement(12753..13553)
                     /locus_tag="U0535_RS02035"
                     /old_locus_tag="U0535_02035"
     CDS             complement(12753..13553)
                     /locus_tag="U0535_RS02035"
                     /old_locus_tag="U0535_02035"
                     /EC_number="3.5.2.6"
                     /function="beta-lactam hydrolysis"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase VIM-4"
                     /protein_id="WP_032492008.1"
                     /translation="MLKVISSLLVYMTASVMAVASPLAHSGEPSGEYPTVNEIPVGEVR
                     LYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIG
                     LPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEAEGNEIPTHSLEGLSSSGD
                     AVRFGPVELFYPGAAHSTDNLVVYVPSANVLYGGCAVHELSRTSAGNVADADLAEWPTS
                     VERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVKAHKNRSVAE"
                     /name="subclass B1 metallo-beta-lactamase VIM-4"
     gene            complement(13644..14198)
                     /locus_tag="U0535_RS02040"
                     /old_locus_tag="U0535_02040"
     CDS             complement(13644..14198)
                     /locus_tag="U0535_RS02040"
                     /old_locus_tag="U0535_02040"
                     /EC_number="2.3.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ib3"
                     /protein_id="WP_032488579.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLAD
                     VQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQLLA
                     NASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTP
                     DGPAVYMVQTRQAFERTRSDA"
                     /name="aminoglycoside N-acetyltransferase AAC(6')-Ib3"
     gene            14378..15391
                     /gene="intI1"
                     /locus_tag="U0535_RS02045"
                     /old_locus_tag="U0535_02045"
     CDS             14378..15391
                     /gene="intI1"
                     /locus_tag="U0535_RS02045"
                     /old_locus_tag="U0535_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_000845054.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     gene            15684..>16265
                     /locus_tag="U0535_RS02050"
                     /old_locus_tag="U0535_02050"
                     /pseudo=""
     CDS             15684..>16265
                     /locus_tag="U0535_RS02050"
                     /old_locus_tag="U0535_02050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017166843.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            16616..17248
                     /gene="parA"
                     /locus_tag="U0535_RS02055"
                     /old_locus_tag="U0535_02055"
     CDS             16616..17248
                     /gene="parA"
                     /locus_tag="U0535_RS02055"
                     /old_locus_tag="U0535_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017154806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="WP_322471704.1"
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLDGADVLLVDSDPQGSAR
                     DWSAVREDQPLTVVGIDRPTIDRDVKNVARKVDFVVIDGAPQAADLAVSAIKAADFVLI
                     PVQPSPYDIWATADLVELVKQRIEVTDGKLQAAFVVSRAIKGTRIGGEVAEALAGYELP
                     ILDARITQRVSYPGTATAGTTVLESEPDGDAAAEVRALAAEIKQKLI"
                     /name="parA"
     gene            17269..17490
                     /locus_tag="U0535_RS02060"
                     /old_locus_tag="U0535_02060"
     CDS             17269..17490
                     /locus_tag="U0535_RS02060"
                     /old_locus_tag="U0535_02060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017154883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015961926.1"
                     /translation="MSKAATTLSAGRPSARTDKSKAATLASLADDASMKRVNFELSADQ
                     HTKLKIYATRQGKTIKELLTEYVASLPD"
                     /name="hypothetical protein"
     gene            17685..18557
                     /locus_tag="U0535_RS02065"
                     /old_locus_tag="U0535_02065"
     CDS             17685..18557
                     /locus_tag="U0535_RS02065"
                     /old_locus_tag="U0535_02065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016851360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="WP_322471705.1"
                     /translation="MTERDQKLIEASAEIATTPPSGEDMAFTHAVLCQVGLPRAKVEGR
                     EFMRQSGAAWVNVQAGYLDEGHGPVLQPIPYGVMPRLGLAWVSTFAVRNKEREIPIGDS
                     AAEFLRLMGMESDGRRYTTLRKQMHALAAARLQLGFKGRTYNGQPVQQFDAWVANKDTQ
                     QRALWPGVMLLSEDYYGSLIESAVPLDNRALHALKGSALALDVYAWLAHRLHRIEGRGV
                     TLHWKSLREQFAQEYKGKDPDKDFKKEFLPVLRKVLAVYPQAKVKPVTGGVLLIGSPPP
                     IPYKGGPTV"
                     /name="replication protein RepA"
     gene            19496..20386
                     /locus_tag="U0535_RS02070"
                     /old_locus_tag="U0535_02070"
     CDS             19496..20386
                     /locus_tag="U0535_RS02070"
                     /old_locus_tag="U0535_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020750540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="WP_032490915.1"
                     /translation="MTQQAPQIPADVRERIIAAAADLFEQSGRETMPTVDAVRRAARVD
                     MNAASAVMKEWRRAQTAQAAPVAVAVPESVQQASSAAVATIWQQAQELANESLRSAQAA
                     WETERAEQDAMRQELAEAFERQAGELEALQSRLASIEAAEATARGEATELRGQLAAAQE
                     QAHTAEARAQEIERRAGELRTELDRAHQTSQAAAAQLDQVRGELAKVQAKAEAEQEAHQ
                     EQRKAAATEAHRMAERLTAAQAERDQATKAAGQAREEAARMAGQIDTLKEQSAALLARI
                     TPAEAKPTRKKPGGE"
                     /name="DNA-binding protein"
     gene            complement(20560..20952)
                     /locus_tag="U0535_RS02075"
                     /old_locus_tag="U0535_02075"
     CDS             complement(20560..20952)
                     /locus_tag="U0535_RS02075"
                     /old_locus_tag="U0535_02075"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_322471706.1"
                     /translation="MAFIIAAVLGVIALAWFLRRLFPALFAAVFVLFAPVWLVGGALLD
                     LLRLPLAFLRPVGLALARLVGFVLVLPLLPFIFAWSFFAELWRQFRPKASPAPAGVKPP
                     TPMQAATRRTADVIDLAAFRQRQEKE"
                     /name="hypothetical protein"
     gene            complement(20963..23488)
                     /locus_tag="U0535_RS02080"
                     /old_locus_tag="U0535_02080"
     CDS             complement(20963..23488)
                     /locus_tag="U0535_RS02080"
                     /old_locus_tag="U0535_02080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020750538.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_088239385.1"
                     /translation="MMDVRDFLARLWAAVVAVFFGAFVLSLANTAHARVFPECNPAAEA
                     AKFYGAEDSDAWVKRVCDAQEAAFQKWENSLQALDVGQQDLAMATNAGNWQAYRDKWAE
                     LLPVLKELEAAAVANRNAPGAANILSLYRNDLGLFLQNAGLASAGSLDDFSARILAGLD
                     GERPAAAATAGVNVVQQSVTRGVEFGKGIGTAQAETILAEYRAQVQQRGAERMEQLGGS
                     TVSGYFGGFGERIKAAFGGWLFYLVTVCFVGAWLAHKRRQNPVTVGTAVGLAFLVPSVG
                     MLLLFVFAPFIPGWFILAATVAGTVATYLNAGRVFGWLAGLVGAESPTGKRLRILGATI
                     ENLRGQVQPSGPVAAAGAAVAAVDNSSTHPLGSHGSARWGTVDEIRQGGHLVAPGKPGG
                     FALGRVSDAPAGLDQRFRFTGHVVTVAPTGSGKGIGAVIPNLLDYPGSALVLDVKGENA
                     AVTARARRALGQAVHVVDPFAVNGDGAAAFNVLDRLDVWNPDCVSESATLADCLVIGSE
                     KAESKFFDESAKNLLQGLMLHVVSLDEPERRNLGELRRLLTTGEGEFFDLLGMMAADET
                     AAFGIPARAANTIMGMADKARGDVISTARTHTAFLDDPRIAAALSRSDFDLSAIKSELM
                     TVFLVMPANRIGPNARFLRLFVGSIIAAITSSNVQPAHRVAFLLDEFGQLGYMKQIEDA
                     VSLLRGYGLAFWVFIQDLSQLKGTYPKWQTFLANSAKSFFGTDDYDTAKYISDSLGKAT
                     IEFETENTGKNSGSGLSGGGGSMNRGKSTGTSQQFTGRELLTPDEVMRLGPEHPIVLVR
                     GERPYLLDRLNYLADAEYAGLFDANPYHS"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            complement(23520..23741)
                     /locus_tag="U0535_RS02085"
                     /old_locus_tag="U0535_02085"
     CDS             complement(23520..23741)
                     /locus_tag="U0535_RS02085"
                     /old_locus_tag="U0535_02085"
                     /inference="COORDINATES: protein motif:HMM:NF018152.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="WP_111961456.1"
                     /translation="MNARREDTRRKIQLGGLVIKSGMSGYPASVILGALTLAAGALNGP
                     NADATKARFEAAGDEAFSDDGEDGGNRS"
                     /name="conjugal transfer protein TraD"
     gene            complement(23764..24015)
                     /locus_tag="U0535_RS02090"
                     /old_locus_tag="U0535_02090"
     CDS             complement(23764..24015)
                     /locus_tag="U0535_RS02090"
                     /old_locus_tag="U0535_02090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020750536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraC family protein"
                     /protein_id="WP_088239386.1"
                     /translation="MARKTLSERKADKLAELNRIKAELAELESKAAERIGKIALAAGLG
                     DLDIDDASLRKEFEAVASKFRKSEGKQAAPMAATNSAD"
                     /name="TraC family protein"
     ARG             complement(12048..12391)
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(13648..14198)
                     /name="aac(6')-Ib3"
                     /gene="aac(6')-Ib3"
                     /gene_name="aminoglycoside N-acetyltransferase AAC(6')-Ib3"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12757..13553)
                     /name="blaVIM-4"
                     /gene="blaVIM-4"
                     /gene_name="subclass B1 metallo-beta-lactamase VIM-4"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(13645..14276)
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="96.67"
                     /coverage="103.45"
     Typing          17553..18557
                     /name="rep_cluster_995"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="83.645"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          90..3379
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.619"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          complement(20967..23488)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="90.725"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcgcactt acgggttgct gcgcaaccct catgcggccg gggatacccc ggcacccctt
       61 tttagcggct aaaacgccaa gggaaaaaat ggcgatctac cacttgaaca cgcacacgat
      121 aggacgggcg gccgggcata gcgccgtggc cgctgccgcc tatcgttccg cgtcgtcgct
      181 ggtagatgag cgcaccggcg aagtgttcga tttcacccgc aaaggcggcg tgttgtcgtc
      241 cgagatagtc acgcccgcag gcgtgccggt tcccgagcgt gccgccttgt ggaatgccgc
      301 cgagaccgcc gagaagcgaa aagatgcgcg agtggcccga gagtggcggg cggccctgcc
      361 gcatgagctg aacgaagccg accgtaaaga gctggcaacg cgcatggggc aggctatcgc
      421 agaccgctac ggcgtggccg tggatgtgtg cattcacgca ccagacaagg agggcgacga
      481 ccggaatttt cacgttcata tgctggcgac cacgcgcacc attcaggccg atggaacgct
      541 aggcgcgaag gccgtcattg agctggcgaa caaagacagg cagaaagcgg gcattcctgg
      601 cacaagccag ggcgacatca tcgagattcg ccagcagtgg gccgagctaa caaacgaggc
      661 gctagagcgg gccggaatca gcgcccgcgt agatcatcgc agctatgcag atcagggcgt
      721 agaactcaca ccaaccaagc acatcggcag cgatgccgtg gcgatggaca ggcgcggcct
      781 ggaggccgac cgcatcgaca ttcacaacgc cgaccggcag gagcaggcgc ggcagattgt
      841 cgagcggccg gagatcatcc tagacaagct cacggccacg caagcggtat tcacgcgccg
      901 cgatattgcc gcagagctga accgctacat tgacgatgcc gaccagttcc agggcttgct
      961 tgccaggctg gaaaattcgc cgcttctggt cgagatggaa ccggccaacg ggcgcgaccc
     1021 ggcgaagttc tctacccgcg aaatgatcga catcgagcgc ggcatggtgg acagtgccga
     1081 gcgcctggcg agaaccggca ggcatggcgt ttccggcccc atcacgaacg cggcgattga
     1141 cggcgcaggc accctatcgg cagagcagca aaacgccgtc cggcacgttc tcaagccggg
     1201 cagcctggcc gtggtcatcg gcgacgccgg cacaggcaaa tcgttctcga tgaaggttgc
     1261 acgcgaggca tggcaagcgc agggcttcaa cgtgcgcggc gcggccctgg cgggcaaggc
     1321 ggccgacgaa ttgcaggcgg gtagcggcat cgacagccgc acgctggcat cccttgaatt
     1381 tgcctggaag aacggaaaag acaaactcac ttcccgcgat gttctggtga tcgacgaagc
     1441 gggcatgatc ggcagccgcc agcttggccg cgtgctgaaa gccgccgagc aggccggggc
     1501 aaaagtcgtc ctgctgggcg acgacaagca gcttgccgcc atagaggcgg gcgcggcttt
     1561 ccggggcgtg gtgcagcatg tcggcgcggc agaaatcacc gaggttcgac gccagaaaga
     1621 ggcatgggcg cgtgccgccg gccaggagct tgcgcgcggt tccgttgccg atggcttggc
     1681 ggcctatgcc gagcgcggcc acgtcaaaat ccacgacagc cgggacgccg cccgcgacag
     1741 cctggcggcc gcttatgtcg gcgaccaggg caagggtagc cagatcatcc ttgcgcacag
     1801 caataaggac gtgcaggcgc tcaatgaagc cgtgcgcgag gcccgcaagg aacgcggaga
     1861 gctgcgcggc acggcccgct ttatgaccga gcgtggcggc cgggaatttg ccccaggcga
     1921 ccgcatcgtg ttcctgaaaa acgaccgcga ccttggcgtt aagaacggca ctcttggcac
     1981 cgtcgagcgt gccgaagatg gaagcctggc cgtgcgcctg gacagcggcg aagcccgccg
     2041 gttccaggcc gcgcaatatg ccgccgtcga tcatggttat gccgtcacga ttcacaaagc
     2101 ccagggcgtt accgtcgata gggcttacct gctggcgacc cctggcatgg ataggagcct
     2161 tgcctatgtc ggcatgaccc ggcaccgcga ggcggcgacc ctgtttgcag gagccgacga
     2221 cttcacagac cgccgcgccg gccgcctggt cgatcatggc gcagcgccct acgagaacaa
     2281 gccggagaac cgggccagct actttgccac tctggaaaac gacaacggcg aacggcacac
     2341 catttggggc gtcgatcttg aacgcgccat tgcggccagc ggcgcgaagc gaggcgaccg
     2401 tatcggcctg gaacatggcg gctctgaaac cgtgcgcctg ccagacggca ccacggccga
     2461 gcgcaacacc tggcacgttc gcggcgcggc cgagctggcc gccggcaagc tggcccaggt
     2521 gctaggccgc gagcgtccga aggaaagcac tttggacttt gccgaccggc gcggctttga
     2581 cggtgaaagc gtggtgcgcc gctggctgga acgtgggcgg gcgaaggtgg ccgagctggc
     2641 cgggaagatg cgcgacggcc tgcgccgcaa cctggaacgc cacggccgcc ccgacctcat
     2701 gcccgcgacc gacattgctg gcacgccaac cgtgcagcgg ccgcagcaga acgagcgcac
     2761 gccagaggac gagaagaagc gccgggcggc cgagatcgcg gcgaagttcc ggcagcaggt
     2821 cagcgaggaa cgcggcgagc aggcagcgcc gcagcagcgg ccccaggccg agcgcccggc
     2881 acccgacccg ctggccggat tccgcgccgg tgtcgagcgt gccgaggcgg caggcggcgg
     2941 cctggccctg gacgtggcga aggcacagct tgccgtcgcc caggagttcc acgcggccgg
     3001 gaaagacccc cggcaccatt cggcggccat catgcaggaa ggccagcagc gggcctttgc
     3061 gggcctggcg cagccgtccc aggccaaggc cgagccggag cgcctggcgg ccgtccaggt
     3121 cagcgaacaa gaccgcaagc gggcagagat gaatgcacgc caagaagtca gccggttcaa
     3181 gacgctggca gcaggccgcc gcaacggcat tgccggttac accgaccgca gcccgtcgaa
     3241 gtggcaggca ttgccgggcg agctgcgcga gcgcatcgag cggttcaatg ccatgccgaa
     3301 agagcgtcag gccgtcgagc tggacaagat gcagcgcgag cttgccgaca ggtatgcacg
     3361 caatccgcag gaaatcacgc gcagccgaca gcagcagcgt gaacaggagc gcggccgcga
     3421 tggcgggcgc gggtattgag ttaaaacgct tttactcatt tgcgtttagt gttatgatgc
     3481 aatgagtaaa tgagaatttg aggtttacgc caggaggaaa gacgatgagc accgaaccga
     3541 cgaacgaaga acttgccaag agctatgcaa cgaagatcga gcaggcccag gagcgccgcg
     3601 aggcgaaaga ccaggagcgg ctagagcggc acggccaggc ggccgcgctg gcatcgcaga
     3661 acatcgaggc cgagcaaccg caggccaagc aggcccaggg cttcgagctg gacgcgcaga
     3721 accaagacag cgcagagcag cgcatcgacc gcaacgagat caacggccag caggcaaaga
     3781 cgctggcaaa ggaattgaac cgcgacaacg agagcggcga ccaggtgaag caagccaggg
     3841 cgcgggaaat cgccgagcgg ttcaaggaga aggcggcacg cgaccgggag cagtcccgca
     3901 gtttcagccg ctaaaaagcg gtgcccagga aggcggcaac ccacctggac acctgaccac
     3961 aacccacctg acatagaggt gaaatcatgg ctacttccaa tgttaccggc cgggcagaac
     4021 ccggtatatc gaaatattgc atcaccttcg gcgtatcgct ggccgcgctc atcctggccg
     4081 gcggcgtgct ggtcttttcc tactggcagc acgtcgagct gctgcatgag ggcgaccgcg
     4141 taggcacgcg cctggaacgc ttgggcctga tcgaccggga gggcgcacag catgagccgc
     4201 gctaaagcct ggcggcgtgc cgcccttgca acctacatcg ccgccggcgc tgcattgacc
     4261 ctggcgggct acaccgtggc gaccacagcc gcgaacgcca acaccctgcg cgacacgcgg
     4321 gagcgcatcg aggacttcca gcgcgagcaa accgccattg ccgagaactc gataagcgcg
     4381 gccagtgtgc ggcgcggcac cctgcccccc gacacccggc cgcctgtcgc gccggactgg
     4441 cccgccctgg ccgagcgcgc catgccatcc gtggtggccc tggcgggcat cgacaagccc
     4501 tatggcaccg gccagaacaa tcacgcctgg cgtattcctg gcgttcaaca gaacgcggct
     4561 acggccgccc tcacccgcat tcgcgcttgg catcgggatt ggccgaaaga ggatgccaag
     4621 cggcggcagc gcatcatctg cggcggcgtg gccgtcgaag gaaacaaggt gctgaccgtg
     4681 gcccattgtg tcgaaggcca ggaagcattg cgcgtgcgca ccgctgccgg cgagtggcgc
     4741 gaggcccgcg tgatcggcgc ggacatttcc cgcgacgtgg cgctgatcga gatcgagggc
     4801 gaccccctgc ccccgattcc ggttgctggc gtcatgcccc gccaggggca ggacgtgatg
     4861 gcgatcggtt cgccaggcgg ctacggcttc gccgtgggcg tgggcatcgt ggcgtggtat
     4921 ggccgcgatg ccgcgatgct ttccccgatg atttcatgct ggtgacggct tcaatcatcg
     4981 gcggcaactc gggcggcgtt gtcgtgaaca ccaggggcga agccgtttca ctggtgagct
     5041 atggctatgg catctacacg cagaccgtgc cgatagaccg cgcccaggca gttgcggccg
     5101 agatcgagcg ccgcgtcgtg cggtaagccc tgcacagaac ccgaaggccg ggcgctgcgc
     5161 ccaggtcgat accggacgcc gccggcgtct cgatgaatcc tcaacctttg gagcaacagc
     5221 tatgaaactt cgcaattcct tcccgctggc ggccgtggcc gcccttctga tcgcttcgac
     5281 cgcgcacgcc ggccaggatg ccgacgcggc ccgcttttcg atcatggccc ctgtccaggc
     5341 ggcttatgac gcctaccagg tcacggcgag ccgggcgcag aacacaatgg acagcatcga
     5401 ggccgagcta cgcgaacccg gcttgtcggc cgagcggcgc gagctgctgg cggtgtcgct
     5461 tgccaccctt cgcgcccgcg aggcggccgc attggagagg ctgcacgctg aatcagcctt
     5521 ggcacagttg aagatggcag actggaacgc gagccggtaa cggcgaccag gaacaagaag
     5581 ggcggccact ggccgccctt ttcacgtctg gatcttgcat cgtcattcct ggcgatgaga
     5641 tccaccgtcg cggccgtcat cgtcggaact ggcgatgttg gccagcccct cgccttccaa
     5701 ggtttcgcag gccactcgcg gccaacggcg ggcgcatcga cccattcccg ttcttcgggc
     5761 ggtagcggct gcgaatagtc ggattcggcc agcagctcat cgagcgtgta gcgcgggcgg
     5821 ctcatcggcg ggcctcatcg agccaggcca gcgtttcagc ttcgcgggcg gccacgcggg
     5881 ccaccagctc gcgcaccagg ccggccaggc tcatgccgtg cgctgccgcg acggcggcag
     5941 cttcggcttt cacgtccgca ggaacggcgg cgctgatggt ggcagcctgg ttcatacggc
     6001 caaatccagc ggcaaatcgg aaatgtcttt caggcgcttg ccatcgacca tcacggccag
     6061 catgtcggcc gcgtcggtca tgcccaaggc ttctaccgtg gcttgcagct catacagggc
     6121 gaagtgatac acgcaatcaa tgtccccggt tcccagggcg atagaggcaa ggcggcttgg
     6181 tgtcggttcg gccgtgacga ccaccacatg aggcagacgg cccttgcggt tgcgcaccag
     6241 gttcaacgct tcggaacggg cgttctgcgc ccggtcgctg cgaattgtcc atttgcatga
     6301 aatgctggcg tgcagcagcg gcaggccgcc gtttttcttc cgcaggctgg caagcgtggt
     6361 cacactgtca tcgaccagga gcgccggggc gttgatggcg ctgtcgtcct cggtgtcgcg
     6421 caccaccaca atatccggcg tgatggtgta gtcgctgccc agggcggccg ccagttcggc
     6481 atcggccttg gcggcccggt cgagcgcgac caggtgcgcg tattgctcat aacgggcaat
     6541 ttccaggcgg ttacggccgg agacttgatg cacgtcccaa atgccgggcc ggaggtggcc
     6601 gagcttgagg aaggtttccc gcacgaagcc tgcgcagatg ccttcaaact ggttgcccga
     6661 agtctggccc gcgatgcgtt cgccgatggt ttcagctttg agcagatcgg caatgccctt
     6721 ggcaatcgcc ttgcttgtgg tgttgctgct atcggcgttg ctcaccacgc ccgcagcatt
     6781 ggtggtcagc gttgcttcca acagctttgc atggaacgct ttgcgggctt ccgagaactc
     6841 ggcgggaaca ctcatcacgc caccttgtag atacgtttga cggacagcgc cgcgaagatt
     6901 tgccgggcca ccgcagcggc caccggcggc ggaaaggcgt tgccgatctg gcgataggcg
     6961 gccgtcttgc ggccggagaa ttgccagtca tcggggaaac cttgaatgcg tgccgtcatg
     7021 cgcgttgtca ggcgcggcat acccacgaaa tcacgcggcg gggcatcgtc ccataggccc
     7081 atgccatcga cgcccagggc ggcccatgcg cgttttgcac gggttgggcc gaggtcaggc
     7141 ccgccgtgtt tcttggaacc gcctaccagc gttggagcaa tgacgttcgc ctgttcgcgc
     7201 caacggttgg caccgcgcca gccgttcgtg gccatgagat cgtgcagcag ttcgcccact
     7261 gtcagcggtt cgctttgcag cggttccggc caggagaagc cgccggccag gtctttacgg
     7321 ataccgacga acaccacacg cgggcgtagt tgcgacacgc catagtcgga ggcgttgaac
     7381 agccgccagc caggcacata gcccaacttt ttgagctgct tttcaacctt gttccggtaa
     7441 tcgtcaaaga cggcatcgag caggccacgc acgttttcca gcatcacagc ttgcgggcgg
     7501 cactcatcga ccaggcggat agcttcgggg aacaagtcgc gctcatcctt cgcgccgagc
     7561 tgctttcctg ccttggagaa cggcgggcat ggcacgccac cggctagcag gtcgatgcct
     7621 tgataggggc ggccatcgaa gcggcgcaaa tcgtcctcaa tgacgttcca ggcgggacgg
     7681 ttcaggcgca gcgttgcaca cgccgccggt tccagttcga ctagggcagc atgatcgaag
     7741 ccagccattt ctaggccgag cgcctggccc cctgcccctg cgcacatttc caaagaattg
     7801 aattggctca tatcgctttt ctcttggttg attgacgtgg cttcctggct gctggtgtcg
     7861 tgaacatatc cggctgcaag ccgccttggt gtcggtcggc gaatgcctgc ataaactcgc
     7921 gcagcacttc cgatgccttc cggttttcag ccaagcaagc cccttggaac gcctcgcgga
     7981 gttccttttc aacacggata cggaggccaa cgtctttgct cgacataagg cgacagtatc
     8041 gcatggatac acaattgtgt atccaaaaaa tcgcacccgt cgcataagtc ctaagttgtg
     8101 cgacagcttg ccatgtcatt ttcagaagac gactgcacgg aatatcagga gtcggctgca
     8161 ctggtggatt gcagcgcggt gtacagggcc gtcttgctca ccttgagccg tgtagcggcc
     8221 tctcggacat taagcccgtt ggcgatgtgc tcccgcgctc gctgcaactt gtcggcggtg
     8281 acaaccggct ttcgcccgcc cttcctccca cgagcggcgg cggcagtcaa cccggccttg
     8341 gtgcgctcgc ggatcaagtc gcgctcgaac tggcccagcg cgccgaacac gtggaagatg
     8401 agccgcccgc ctggcgtggt ggtgtcgatg gcttccgtca gagaacggaa gccgacgcct
     8461 cgcgcttcca gcgcgcctat cgtttcgatt aggtgcggca tagagcgccc gagccgatcc
     8521 agccgccaga cggccagcac gtcgccgtcg cgcaggtagg ccagcgcatc agccaagccg
     8581 gggcggtcgg ccttggcccc ggaagccgtg tcctcgaaaa cgcgctcgca gcctgccttg
     8641 cgtagcgcat ccgtctgcaa ggcggtgtcc tgttccgccg tcgatacccg cgcatagccg
     8701 atcagtgcca tttgccgcct ctcttgtccg tcattccgtc cgcctatctt aatgtccgac
     8761 aacccgttgt gcaataactt tgctggacag tgtccggcat ggccgactaa tgatcgtttg
     8821 acggacattg acggtaaggc atttttgcat tactatgtga agcatcaacc ttgattgcga
     8881 gggcaaacca ccatgaccac attgaccgtt accgcacggg gacaagtgac gtttcggaag
     8941 gacgtactgc aacacctcgg catcaggcca ggcgacaaga tcgagctgga cttgttgcca
     9001 gacggtcggg gcgtgctcaa ggcggcacgg cccgcaggga cgatagccag ctttgtcggc
     9061 ctgctcgcgg gcaagacgca gaaggttgcc accatcgaag aaatcaacga ggcggcggcg
     9121 caaggctggg caggtaagca atgaaggtcg cagtcgatac caacgtcctt gtgcgtgcgg
     9181 ttgtgcgtga cgatcccgca caagcggacg ttgccgccgc agtcttgacc gacgccgagt
     9241 tgatcgcggt cgcgctgccg tgcctatgcg aatttgtttg ggtgctgctg cgtgtctacg
     9301 gcttccagca agccgacgcg gccagcgcga tccgggcact actggccgcc gcgaatgtgg
     9361 aagtgaaccg gcctgccgtg gaggctggct tgctggtgct cgacgcgggc ggagactttg
     9421 ccgatggcgt cattgcctac gaaggcaact ggcttggcgg ggaaaccttc gtttccttcg
     9481 ataagaaggc ggtggcactt ctcacggcgc aagggcaatc aacgcgcctt ttgtgacgga
     9541 catgagcatg aacgaattcc gccgactggc cgcgaagatc gaccaacaca tgcagcagct
     9601 tgccgcccag ggtgtcagcg aggcccatgc catcatcaat cgcatgatgg ggtacgggcc
     9661 tgacctgcac aggatttggg tcggcacatc cgatcagcag ctcatggcgc tgtcccgcga
     9721 gttcccaggg ttctaccgct acgcccgcat catggaagag gcatccgaag ccgagcgccg
     9781 caaggcttcg cggccctatg acggcatggc cgagttctcc gaacagcaca agcaaatggg
     9841 cgcgcaactg ctgaccacgg cggccacgct tgagcgtggc taccaggcgt ttcgtgcgag
     9901 cggcagtctc caagacttcc ggcctcagct cgacgagctg ggccgcctgc atcggcaatg
     9961 gctgtccgac ctggaagcct tcaaagactc gctgcgcacg cagggcgcag aacccaaggt
    10021 gctggaatac gtgaacgagg ctttcggccg cctggccgag cgcatcaagc agcttgccgg
    10081 ttgatcgccg gaattttcgg cggttccggc tttgtcgcgc cgtgcacaag agttctgagc
    10141 aattccgatc tctcgcggcg cttcgtgcat agaacttctg accgttcccg gtcagaagtt
    10201 ctatgcacac acggcggcca gcccagtgaa ctggtgcagt cgccttctga aaacgacagc
    10261 tttggtatct ctcataaacg gatgtttttg agagaactat cttcggcctt cacacgcacg
    10321 aaaggcggcg aagctccgcc gttaatccgt ccgccggaga tctcgcccag gcaggctgaa
    10381 ggccgagcaa gcctgacagg cccgaaaagc ccggcacggg cgtcggcggc gatgacggcg
    10441 gcggcattat ccagggttga tgatggaagt ggaggatatc gacaacctct cgcgcaacca
    10501 agacatcgcg gtcggactgc aagtgatctt gaagccacgg gcccgtccca ccccgacatg
    10561 gacctcgatg cccgaacgga cgttagattt cgagttctag gcgttctgcg atgaaggttg
    10621 gatcccagcc gggattgaaa gtgtcgacgt gggtgaatcc gagccgctcg tataggccac
    10681 gcaggttcgg gtggcagtcg agccgcagct tggcgcaccc ctgcgttcgc gcggcatggc
    10741 ggcaagcctc gatcagcgcg gagctgacac cccggcccgc atgtgtccgt cgcaccgcga
    10801 gcttgtgcag atatgcggcc tcccccttga gggcgtcggg ccagaactcg ggatcctcgg
    10861 ccgacaaggt gcaacagccg acgatgccgt cgctgcaact cgcgactagg agctcggatc
    10921 tcaggacgaa ggtctccgcg aatgtccggt cgatccgcgc gacgtcccag gcgggcgttc
    10981 ccttggcgga catccacgcc gcagcgtcgt gcatcagccg cacaacctcg tcgatatcac
    11041 ccgagcaggc gacccgaacg ttcggaggct cctcgctgtc cattcgctcc cctggcgcgg
    11101 tatgaaccgc cgcctcatag tgcagtttga tcctgacgag cccagcatgt ctgcgcccac
    11161 cttcgcggaa cctgaccagg gtccgctagc gggcggccgg aaggtgaatg ctaggcatga
    11221 tctaaccctc ggtctctggc gtcgcgactg cgaaatttcg cgagggtttc cgagaaggtg
    11281 attgcgcttc gcagatctcc aggcgcgtgg gtgcggacgt agtcagcgcc attgccgatc
    11341 gcgtgaagtt ccgccgcaag gctcgctgga cccagatcct ttacaggaag gccaacggtg
    11401 gcgcccaaga aggatttccg cgacaccgag accaatagcg gaagccccaa cgccgacttc
    11461 agcttttgaa ggttcgacag cacgtgcagc gatgtttccg gtgcggggct caagaaaaat
    11521 cccatccccg gatcgaggat gagccggtcg gcagcgaccc cgctccgtcg caaggcggaa
    11581 acccgcgcct cgaagaaccg cacaatctcg tcgagcgcgt cttcgggtcg aaggtgaccg
    11641 gtgcgggtgg cgatgccatc ccgctgcgct gagtgcataa ccaccagcct gcagtccgcc
    11701 tcagcaatat cgggatagag cgcagggtca ggaaatcctt ggatatcgtt caggtagccc
    11761 acgccgcgct tgagcgcata gcgctgggtt tccggttgga agctgtcgat tgaaacacgg
    11821 tgcatctgat cggacagggc gtctaagagc ggcgcaatac gtctgatctc atcggcaggc
    11881 gatacaggcc tcgcgtccgg atggctggcg gccggtccga catccacgac gtctgatccg
    11941 actcgcagca tttcgatcgc cgcggtgaca gcgccggcgg ggtctagccg ccggctctca
    12001 tcgaagaagg agtcctcggt gagattcaga atgccgaaca ccgtcaccat ggcgtcggcc
    12061 tccgcagcga cttccacgat ggggatcggg cgagcaaaaa ggcagcaatt atgagcccca
    12121 tacctacaaa gccccacgca tcaagctttt gcccatgaag caaccaggca atggctgtaa
    12181 ttatgacgac gccgagtccc gaccagactg cataagcaac accgacaggg atggatttca
    12241 gaaccagaga aagaaaataa aatgcgatgc cataaccgat tatgacaacg gcggaagggg
    12301 caagcttagt aaagccctcg ctagatttta atgcggatgt tgcgattact tcgccaacta
    12361 ttgcgataac aagaaaaagc cagcctttca tgatatatct cccaatttgt gtagggctta
    12421 ttatgcacgc ttaaaaataa taaaagcaga cttgacctga tagtttggct gtgagcaatt
    12481 atgtgcttag tgcatctaac gcctgagttg aggggctttt gcggagtagg cgcagcctgc
    12541 gtagcaaaag tcccgctcca acgatttgtt atgccgcatc tgctactcgg cgactgagcg
    12601 atttttgtgt gctttgacaa cgttcgctgt gtgctggagc aagtctagac cgcccggtag
    12661 accgtgcccg ggaatgacga cctctgcttc cgggtagtgt ttttgaatcc gctcaacgga
    12721 ggtgggccat tcagccagtt atgccgcatc tgctactcgg cgactgagcg atttttgtgt
    12781 gctttgacaa cgttcgctgt gtgctggagc aagtctagac cgcccggtag accgtgcccg
    12841 ggaatgacga cctctgcttc cgggtagtgt ttttgaatcc gctcaacgga ggtgggccat
    12901 tcagccagat cggcatcggc cacgttcccc gcagacgtgc gtgacaactc atgaacggca
    12961 caaccaccgt atagcacgtt cgctgacggg acgtatacaa ccagattgtc ggtcgaatgc
    13021 gcagcaccag gatagaagag ctctactgga ccgaagcgca ctgcgtcccc gctcgatgag
    13081 agtccttcta gagaatgcgt gggaatctcg ttcccctctg cctcggctag ccggcgtgtc
    13141 gacggtgatg cgtacgttgc caccccagcc gcccgaagga catcaacgcc gccgacgcgg
    13201 tcgtcatgaa agtgcgtgga gactgcacgc gttacgggaa gtccaatttg cttttcaatc
    13261 tccgcgagaa gtgccgctgt gtttttcgca ccccacgctg tatcaatcaa aagcaactca
    13321 tcaccatcac ggacaatgag accattggac gggtagaccg cgccatcaaa cgactgcgtt
    13381 gcgatatgcg accaaacacc atcggcaatc tggtaaagtc ggacctctcc gaccggaatt
    13441 tcgttgactg tcggatactc accactcggc tccccggaat gggctaacgg acttgcgaca
    13501 gccatgacag acgcggtcat gtagaccaat aaactactaa taacttttaa catcaagact
    13561 ccataggggt gggtgcggca taacgtttga catgaggggc ggccaagggc gccagccctt
    13621 ggacgtcccc ctcgatggaa gggttaggca tcactgcgtg ttcgctcgaa tgcctggcgt
    13681 gtttgaacca tgtacacggc tggaccatct ggggtggtta cggtaccttg cctctcaaac
    13741 cccgctttct cgtagcatcg gatcgctcgc aagttgctcg gcgacgggtc cgtttggatc
    13801 ttggtgacct cgggatcatt gaacagcaac tcaaccagag ctcgaaccag cttggttccc
    13861 aagcctttgc ccagttgtga tgcattcgcc agtaactggt ctattccgcg tactcctgga
    13921 tcggtttctt cttcccacca tccgtccccg cttccaagag caacgtacga ctgggcatac
    13981 ccaatcggct ctccattcag cattgcaatg tatggagtga cggactcttg cgctaaaacg
    14041 cttggcaagt actgttcctg tacgtcagca agtgtcgggc gtgcttcttc tccgccccac
    14101 cactcgacga tatgagatcg atttagccac tcatagagca tcgcaaggtc atgctcagtc
    14161 atgaggcgca gtgtgacgga atcgttgctg ttggtcacga tgctgtactt tgtgatgcct
    14221 aactttgttt tagggcgact gccctgctgc gtaacatcgt tgctgctgcg taacatcgtt
    14281 gctgctccat aacatcaaac atcgacccac ggcgtaacgc gcttgctgct tggatgcccg
    14341 aggcatagac tgtacaaaaa aacagtcata acaagccatg aaaaccgcca ctgcgccgtt
    14401 accaccgctg cgttcggtca aggttctgga ccagttgcgt gagcgcatac gctacttgca
    14461 ttacagttta cgaaccgaac aggcttatgt caactgggtt cgtgccttca tccgtttcca
    14521 cggtgtgcgt cacccggcaa ccttgggcag cagcgaagtc gaggcatttc tgtcctggct
    14581 ggcgaacgag cgcaaggttt cggtctccac gcatcgtcag gcattggcgg ccttgctgtt
    14641 cttctacggc aaggtgctgt gcacggatct gccctggctt caggagatcg gaagacctcg
    14701 gccgtcgcgg cgcttgccgg tggtgctgac cccggatgaa gtggttcgca tcctcggttt
    14761 tctggaaggc gagcatcgtt tgttcgccca gcttctgtat ggaacgggca tgcggatcag
    14821 tgagggtttg caactgcggg tcaaggatct ggatttcgat cacggcacga tcatcgtgcg
    14881 ggagggcaag ggctccaagg atcgggcctt gatgttaccc gagagcttgg cacccagcct
    14941 gcgcgagcag ctgtcgcgtg cacgggcatg gtggctgaag gaccaggccg agggccgcag
    15001 cggcgttgcg cttcccgacg cccttgagcg gaagtatccg cgcgccgggc attcctggcc
    15061 gtggttctgg gtttttgcgc agcacacgca ttcgaccgat ccacggagcg gtgtcgtgcg
    15121 tcgccatcac atgtatgacc agacctttca gcgcgccttc aaacgtgccg tagaacaagc
    15181 aggcatcacg aagcccgcca caccgcacac cctccgccac tcgttcgcga cggccttgct
    15241 ccgcagcggt tacgacattc gaaccgtgca ggatctgctc ggccattccg acgtctctac
    15301 gacgatgatt tacacgcatg tgctgaaagt tggcggtgcc ggagtgcgct caccgcttga
    15361 tgcgctgccg cccctcacta gtgagaggta gggcagcgca agtcaatcct ggcggattca
    15421 ctacccctgc gcgaaggcca tcggtgccgc atcgaacggc cggttgcgga aagtcctccc
    15481 tgcgtccgct gatggccggc agcagcccgt cgttgcctga tggatccaac ccctccgctg
    15541 ctatagtgca gtcggcttct gacgttcagt gcagccgtct tctgaaaacg acatgccacc
    15601 ctgccctttc cctggcgttt tttgtcgcgt gttttagttg catgaaatag aatacttgcg
    15661 actagaaccg gagacattac gccatgaaag acaagagcgc cgccgctggc ctgctgctgg
    15721 gatatgcccg cgtcagcacc gacgaccagg acttgaccaa ccaacgcgcc gagctgcacg
    15781 ccgcaggctg cacgcgcatc tttgccgaga agatcaccgg caccaggcgc gacaggcccg
    15841 agctggcccg cgtgctcgat cacttgcgcc ctggcgatgt tgtgactgtg accaggcttg
    15901 accgcctggc ccgcagcacc cgcgacctgc tggacattgc cgagcgtatc caggcggtcg
    15961 gcgcgggttt gcgcagcctg gccgagccgt gggccgacac caccaccccg gccggccgca
    16021 tggttctgac cgtgtttgcc ggcatcgccg agttcgagcg ttccctaatc atcgaccgca
    16081 ccaggaacgg ccgggaagcg gccaaggccc gaggcgtgaa gttcggcccg cgccctaccc
    16141 tcaccccggc gcagatcgag cacgcccgcg agctgatcga ccgtgacggc cggacggtga
    16201 aggaagcggc cgagctgctg gccgtgcatc gttcgaccct ttaccgggcg ctggcgcgtg
    16261 gcgaggaagt gacaaagacc gaggcccgcc gacgtggtgc gttcgccgag gacgcattga
    16321 gcgaagccga cgccctggcg gccgtcgatg atgaacgcca ggaagaaggc cccgcgttcc
    16381 tcgatggcga cggcccggcc gccgacctgc cgccgccgcc gtatcgaacg cagagcctgc
    16441 cgcaaatcct ggcggccctc cccgatgacg agctggcgag ctggcccggt gagctggccg
    16501 accaggagcg ggaacggcgt attgcggcta aatgatgata agtgctttta ctcattcgct
    16561 cattgtgcta tgatgcaatg agtaagccat catccgcact acaccgggag aacacatgaa
    16621 agtcattgcc gtgctgaacc agaagggcgg gagtggaaaa accaccatcg ccacccacct
    16681 tgcccgcgcc ttgcaactgg acggcgccga cgtgctgcta gtcgattccg acccccaggg
    16741 cagcgcccgc gattggtcag ccgtgcggga agatcagccg ctaaccgttg tcggcatcga
    16801 ccggccgacc attgaccggg acgtgaagaa cgtagcccgc aaggtggatt ttgtcgtgat
    16861 cgacggcgca ccccaagcgg ccgacctggc cgtgtcggcc atcaaggcgg ccgacttcgt
    16921 gctgattccg gtgcagccat cgccttacga catttgggcc acggccgacc tggtggagct
    16981 ggtcaagcag cgcatcgagg tcacggacgg aaaactacag gccgcctttg ttgtatcgcg
    17041 tgccatcaag ggcacccgca ttggcggaga agttgccgag gcgttggccg gctacgagct
    17101 gcccattctg gatgcccgca tcacgcagcg cgtgagctat cccggcacgg ccaccgccgg
    17161 cacgaccgtt cttgaatccg agccggacgg cgatgcagcg gccgaggttc gcgccctggc
    17221 cgccgaaatc aagcaaaaac tcatttgata ctttaaggaa ataaagaaat gagcaaagca
    17281 gcaaccacac tcagcgccgg ccgcccgagc gcacgcacgg acaaatccaa ggccgccacg
    17341 cttgccagcc tggccgacga cgccagcatg aagcgggtca attttgaact gtcggccgac
    17401 cagcacacca agctgaaaat ctacgcaacc cggcagggca agaccatcaa ggaactattg
    17461 accgagtatg tcgccagcct gccggattga cgctcaaaca catatttact catttgaatt
    17521 ttagcggcta aagggcgaag ccatgacaaa gaagcagcga gaagggcagg gcgcgcagca
    17581 gatcggcgag atcatgggcg acctactggc ccaggcgcag atcaaagcgg cgttgccgcc
    17641 cccaaagcgc caaaccaaga agatcacgcc tggcaggcct catcttgacc gagcgcgatc
    17701 aaaagctgat cgaggccagc gcggagattg ccactacccc cccgagtggc gaggacatgg
    17761 ctttcactca tgccgtgctg tgccaggttg gtttgccccg cgccaaggtg gaaggccgcg
    17821 agttcatgcg gcagtccggc gcggcttggg tcaatgtcca ggccggctac ctggacgaag
    17881 ggcatggccc ggttctgcaa cctatcccct atggcgtcat gccccggctt ggcctggcgt
    17941 gggtttccac cttcgccgtg cgcaacaaag agcgcgaaat ccccatcggt gacagcgccg
    18001 ccgagttcct gcggctcatg gggatggaga gcgacggccg ccgctatacg accttgcgga
    18061 agcagatgca cgccttggcc gccgctcgcc tgcaactcgg attcaaaggg cgtacctaca
    18121 acggccagcc agtgcagcag ttcgatgctt gggtggcgaa caaggacacg cagcagcgcg
    18181 ccctatggcc tggcgtcatg ctgctgtcag aggactatta cggctccctg atcgaaagcg
    18241 ccgtgccgct ggacaaccgc gctttgcacg ccctgaaagg ttccgcactg gcgttggacg
    18301 tgtacgcctg gctggcccat cggctgcacc gcatcgaggg cagaggggta acgctgcact
    18361 ggaagtcgct gcgcgagcag ttcgcccagg aatacaaggg caaagacccg gacaaggatt
    18421 tcaagaagga gtttttgccg gtgctgcgca aggtgctggc cgtctatccg caggccaagg
    18481 tgaagcctgt caccggcggc gtgctgctga tcggctcgcc accgcccatt ccctacaagg
    18541 gcggccccac ggtttagcta aacttcgtga aatcgccccc cccttgcagc accgcaccgg
    18601 ccgccccaga tcgaggcggc cgcgtcgttt ctggcgtgac ctgaccagca cctacccccg
    18661 agcggtcgaa ctggggataa accctgtgga tagctgcact tatccacgtg aaatcgcccc
    18721 ccccaggttc gtgaaatcgc cccccccttc gcggcttatc cacgtgaaat cgcccccccc
    18781 tttccacgtg aaatcgcccc ccccctaaac ctgtaaggta atcctttaag attttttcct
    18841 ataaatactt gcctgtaatt ggcaggcaaa atcggtggaa aactcgaccg gcagcgcaaa
    18901 ccgaaccacc gcaacgccct acgggcgcgc ctgccctccg gtcgcttcgc tcccttcgcc
    18961 ccgccgcttc gcgtcggcct atcgcggccg atggccgctc aaaaatggct ggcctgcggc
    19021 caggcatcta ccaggcgcgg cacgccgcgc cggtgccaac tccaccgcct gcgcccacat
    19081 ccagcaccgc ggccgctgaa aggtcgtcaa aagcggttta gcagggaaaa gcaggcaggc
    19141 cgaccgtctg cgctcaactc gaacacctgc gcgagctgga aggccgcaag gttgaacgcc
    19201 aagaaagaag ggccgccagg ctatcgaact ggccagcatc gccatatccg acgatgacaa
    19261 ccgccaagca atgcacccaa gccgcacagg gacgcgcagg aggcgcgaaa gagggccgag
    19321 ggtaggggat aggtgccgcc gaccccaaaa acgccgccac gggccccaca gggccgaatt
    19381 tcggccgcca cgcgctcccg gccgggccga cccgagaacc gggcgcaaat aacgcttgca
    19441 taagaacaat aagaataata ttattattct tatcttatcc gccggagcca aggccatgac
    19501 gcagcaagcc ccccaaattc ccgccgacgt gcgcgaacgc atcattgccg ccgccgccga
    19561 tcttttcgag cagtcgggcc gcgagacgat gcccacggtc gatgccgtgc gccgtgccgc
    19621 ccgcgtggac atgaacgccg ccagtgccgt gatgaaggaa tggcgcaggg cgcagacggc
    19681 ccaggccgcg ccggtggccg tagccgtgcc ggaatccgtg cagcaggcca gcagcgccgc
    19741 cgtggcgacg atctggcagc aggcccagga gctggcgaac gaatccctgc gcagcgcaca
    19801 ggccgcatgg gaaaccgagc gggcagagca agacgccatg cggcaagagc tggccgaggc
    19861 tttcgagcgt caggccggcg agctggaagc cttgcaatcc cgcctggcgt ccatcgaggc
    19921 cgccgaagcg accgcacgcg gcgaagctac cgagctgcgc ggccaactgg ccgccgccca
    19981 ggagcaggcg cacacggccg aggcccgcgc ccaggagatc gagcgccgcg ccggtgagct
    20041 acgcacggag ctggacaggg cgcaccagac cagccaggcc gccgccgccc agctcgacca
    20101 ggtgcgcggc gaactggcga aggtgcaggc caaggccgaa gccgaacagg aagcgcacca
    20161 ggaacaacgc aaggccgcag caaccgaagc gcaccgcatg gccgaacgcc tcaccgctgc
    20221 ccaggccgaa cgcgatcagg ccacgaaagc cgccggccag gcccgcgagg aagccgcacg
    20281 catggcaggg caaatcgaca cgctcaaaga gcaatccgcc gcgctgctgg cccgtatcac
    20341 gccagccgaa gccaagccga ccaggaagaa gcccggcggc gagtgaatgc ctgcccctca
    20401 agtgtcaata acccgcctcg ctggccggtt tgcacaagcg cagacaaaga aaaggccgga
    20461 agcatggggc gctttccggc ctgatattga cacttgaggg gcggcccatt ttagccgcta
    20521 aaatcattta ctcataaaag gtaaaactca aaaactcttt tattcttttt cctgccgctg
    20581 gcggaatgcc gccaggtcga tcacgtccgc cgtgcgcctt gtggcggcct gcatcggcgt
    20641 gggcggcttg accccggccg gggccgggct ggcctttggc cggaactgtc gccacagttc
    20701 cgcgaagaac gaccaggcga agatgaaggg cagcagcggc agcaccagga cgaagccgac
    20761 caggcgggcc agggcgaggc cgaccggccg caggaaggcc agcggcaggc gcagcagatc
    20821 gagcagcgca ccgccgacca gccataccgg cgcgaacagg acgaacaccg ccgcaaacag
    20881 ggcagggaac agccgccgca ggaaccacgc cagggcgatg acaccgagaa ccgccgcgat
    20941 gatgaacgcc atacgtcatc cctcaactat ggtagggatt cgcgtcgaac agcccggcat
    21001 attcggcatc ggccaggtag ttcagccggt cgagcaggta ggggcgttcc ccgcgcacca
    21061 ggacaatcgg atgctccggc cccaggcgca tgacttcatc cggcgtcagc agttcgcgcc
    21121 cggtgaattg ctggcttgtg ccggtgctct tgccccggtt catcgagccg ccgccgcctg
    21181 ataggccgct gccgctgttc ttgccggtgt tttccgtctc aaactcaatc gtggctttgc
    21241 ccaggctgtc gctgatgtat ttggccgtgt cgtaatcgtc agtgccaaag aagcttttgg
    21301 cgctgttcgc caggaaggtc tgccacttgg gataggtgcc tttgagctgc gacaggtctt
    21361 gaatgaacac ccagaaggcc aggccgtagc cgcgcagcag tgaaacggcg tcctcgatct
    21421 gcttcatgta gccgagctgg ccgaactcat cgagcaggaa cgcgacccgg tgcgccggct
    21481 gcacgttact ggacgtgatc gcggcaatga tcgacccgac aaacaagcgc aggaaacgcg
    21541 catttgggcc gatgcggttg gcgggcatga ccaggaacac cgtcatcaat tcggacttga
    21601 tcgcggacag gtcgaagtcg gagcgcgata gcgccgctgc aatgcgcgga tcgtccaaga
    21661 aggcggtatg cgtgcgggcc gttgaaatca cgtctccccg cgccttgtcg gccatgccca
    21721 tgatggtatt cgcggccctg gccgggatgc cgaaggcggc cgtttcgtcg gcggccatca
    21781 tgcccaggag gtcgaaaaac tcgccttcac ccgtggtcag caagcggcgc agctcgccca
    21841 ggttccgccg ttccggctca tccaggctaa caacgtgaag catcagtcct tgaagtaggt
    21901 ttttagccga ctcatcgaag aacttggatt cggctttctc gctgccgatc actaggcaat
    21961 cggccagcgt ggcggattcg ctcacacaat ccgggttcca cacgtccagg cgatccagga
    22021 cgttgaaagc ggccgcgccg tcgccattga ccgcgaacgg atcgaccaca tgcacggcct
    22081 ggccgagcgc ccggcgggcg cgagccgtca cggccgcgtt ttcgcccttc acgtcgagaa
    22141 ccagggccga tccgggatag tccaggaggt tcggaatcac cgcgccaatg cccttgccgg
    22201 agccggtcgg ggccacggtc acgacatggc cggtaaagcg gaaacgctga tcgaggccgg
    22261 cgggcgcatc cgacacccgg ccaagggcga agccgcccgg cttaccaggc gcgaccaggt
    22321 ggccgccctg gcggatttca tcgaccgttc cccaacgggc cgagccgtgc gaacccagcg
    22381 gatgcgtgct gctgttatcg accgccgcga ccgccgcacc ggcggccgca actggcccgg
    22441 acggttgcac ctggccgcgc aggttttcaa tcgttgcgcc gaggatgcgc agccgctttc
    22501 ctgtcggaga ctccgcgccg accaggcccg cgagccagcc gaacacccgg cccgcgttca
    22561 gatacgttgc cactgttccg gcgaccgtcg cggcgaggat gaaccagccc ggaatgaatg
    22621 gcgcgaacac gaacagaagc aacatgccga ccgatggaac gaggaaggcc agaccaacgg
    22681 ccgtgccgac cgtcacaggg ttctgccgtc gcttgtgcgc cagccacgcg ccgacaaagc
    22741 agaccgtgac caggtagaac aaccagccac cgaaagccgc cttgatgcgc tcgccgaaac
    22801 cgccgaaata gccgctcacg gtcgagccgc cgagctgttc catgcgttcc gcgccgcgct
    22861 gctgaacttg ggcgcgatac tccgcaagaa tcgtttccgc ttgtgccgtc ccgatgccct
    22921 tgccgaactc aacgcctcgc gtcacggatt gctgcacgac attgacgcca gccgttgccg
    22981 ccgccgctgg ccgttcgccg tccaggcccg ccagaatccg ggcgctgaaa tcgtccaggc
    23041 tgcccgccga ggcaaggccc gcattctgca agaacaggcc caaatcgttg cgatacagac
    23101 taaggatgtt tgccgcgcct ggcgcgttcc ggttcgccac cgcagcggct tccagttcct
    23161 tcaacaccgg cagcaattcg gcccacttgt cccggtaggc ttgccaattc ccggcgttcg
    23221 tcgccatcgc caaatcctgc tgcccaacgt ccagggcttg caggctgttt tcccacttct
    23281 ggaatgccgc ctcttgcgca tcacaaacgc gcttcaccca ggcatccgaa tcttccgcgc
    23341 cgtagaactt cgcggcctct gccgccgggt tgcattcagg gaaaacgcgg gcgtgcgccg
    23401 tgttcgccaa cgacagcacg aacgccccaa aaaataccgc tacgacagcg gcccacaatc
    23461 tcgccaaaaa atctctaacg tccatcatgc ttcacctcta tgtcaggttg aattgacggc
    23521 taggaacggt tgccgccgtc ctctccatca tcggaaaaag cctcatcgcc tgccgcctca
    23581 aagcgtgctt ttgtagcgtc agcgtttggc ccatttagcg caccggccgc gagggtcaaa
    23641 gcgcccaaaa tcacagacgc cggatagccc gacatgccgg actttatgac caagccgccg
    23701 agctggattt tccggcgggt atcttctctc ctggcgttca tccgaaggcg tcccaaatcg
    23761 cgctcaatct gcgctattcg ttgccgccat cggggcagct tgcttgcctt cgcttttgcg
    23821 aaatttcgag gcgacagcct caaactcctt ccgcaatgaa gcgtcgtcta tgtcgagatc
    23881 gccgaggcca gcggcaaggg caatcttacc aatgcgttca gcggccttgc tttccaattc
    23941 ggccagttct gccttgatgc ggttcagttc ggccagcttg tcggccttgc gttcggataa
    24001 cgtctttcgt gccatcgtca tagctccttt cgagattgtg ggttatgcgc acacgatctt
    24061 accaccggcg acgctggcgg ggaaggcgcg gcgctggtat agtcatggag cgaaagcgaa
//
