LOCUS       NZ_CP139680            19459 bp    DNA     circular CON 11-MAY-2024
DEFINITION  Escherichia coli strain TP6-1 plasmid p3, complete sequence.
ACCESSION   NZ_CP139680
VERSION     NZ_CP139680.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38111791
            Assembly: GCF_034339465.2
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19459)
  AUTHORS   Tian,D.
  TITLE     The evolution and transmission of ST65 Klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19459)
  AUTHORS   Tian,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2024) Clinical Laboratory, Affiliated Hospital of
            Jining Medical University, No. 89, Guhuai Road, Jining, Shandong
            272000, China
  REMARK    Nucleotide sequence updated by submitter
REFERENCE   3  (bases 1 to 19459)
  AUTHORS   Tian,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2023) Clinical Laboratory, Affiliated Hospital of
            Jining Medical University, No. 89, Guhuai Road, Jining, Shandong
            272000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 205x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_034339465.2-RS_2024_05_11
            Annotation Date                   :: 05/11/2024 02:02:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,898
            CDSs (total)                      :: 4,779
            Genes (coding)                    :: 4,540
            CDSs (with protein)               :: 4,540
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 14
            Pseudo Genes (total)              :: 239
            CDSs (without protein)            :: 239
            Pseudo Genes (ambiguous residues) :: 0 of 239
            Pseudo Genes (frameshifted)       :: 75 of 239
            Pseudo Genes (incomplete)         :: 174 of 239
            Pseudo Genes (internal stop)      :: 46 of 239
            Pseudo Genes (multiple problems)  :: 55 of 239
            Pseudo Genes (short protein)      :: 4 of 239
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP139680.2.
            On May 11, 2024 this sequence version replaced NZ_CP139680.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19459
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="TP6-1"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p3"
                     /geo_loc_name="China: Shandong"
                     /lat_lon="31.23 N 121.45 E"
                     /collection_date="2023-02-22"
                     /collected_by="Dongxing Tian"
     gene            join(19207..19459,1..11)
                     /locus_tag="UMY46_RS24400"
                     /old_locus_tag="UMY46_24430"
     CDS             join(19207..19459,1..11)
                     /locus_tag="UMY46_RS24400"
                     /old_locus_tag="UMY46_24430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004146443.1"
                     /translation="MSNTTHYENANFLRELAENLPRILPESDPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            1..300
                     /locus_tag="UMY46_RS24405"
                     /old_locus_tag="UMY46_24425"
     CDS             1..300
                     /locus_tag="UMY46_RS24405"
                     /old_locus_tag="UMY46_24425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_023389908.1"
                     /translation="MPYDVEWKQGAIEDVTMLFDYIAENSSLWDAQNVTDRVLTAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(362..739)
                     /locus_tag="UMY46_RS24410"
                     /old_locus_tag="UMY46_24420"
     CDS             complement(362..739)
                     /locus_tag="UMY46_RS24410"
                     /old_locus_tag="UMY46_24420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004146445.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQGETHERDGLRLPDETEKTASDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTPRRWWQWGKR"
                     /name="hypothetical protein"
     gene            808..987
                     /locus_tag="UMY46_RS24415"
                     /old_locus_tag="UMY46_24415"
     CDS             808..987
                     /locus_tag="UMY46_RS24415"
                     /old_locus_tag="UMY46_24415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1015..1485)
                     /locus_tag="UMY46_RS24420"
                     /old_locus_tag="UMY46_24410"
     CDS             complement(1015..1485)
                     /locus_tag="UMY46_RS24420"
                     /old_locus_tag="UMY46_24410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_322265842.1"
                     /translation="MPTSEHLEDMVVLAWQTGAYVFCFVDRTQHLAMMKSIGMYDERLN
                     SDEKATYFFTGENPQWERDKPAGMKLCDYLYRKVERFAIENGVQVVDAGKCSPEQISAM
                     IEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPEDKSARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(1674..2534)
                     /locus_tag="UMY46_RS24425"
                     /old_locus_tag="UMY46_24405"
     CDS             complement(1674..2534)
                     /locus_tag="UMY46_RS24425"
                     /old_locus_tag="UMY46_24405"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            complement(3355..4725)
                     /locus_tag="UMY46_RS24430"
                     /old_locus_tag="UMY46_24400"
     CDS             complement(3355..4725)
                     /locus_tag="UMY46_RS24430"
                     /old_locus_tag="UMY46_24400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000971921.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISCfr1 family transposase"
                     /protein_id="WP_000971921.1"
                     /translation="MMGQLPGGQQRLFYSFNLEDHVPAQHLLRSIDQCLDLSDLRAYLA
                     DFYSPIGRPSIDPELMVRMLVVGYCYGIRSERRLCEEVHLNLAYRWFCRLGLEDEVPNH
                     STFSKNRHGRFRDSDLFRWLFNEVLRRCMAAGLVKGEGFAVDASIIKADASRQRGVAGD
                     EVDWNDPKLSSRAVREYLEALDEEALAEALPKKISLTDPQSRWTAAPGGPAFFAYSTNY
                     LIDTEHGVIMDVEATPAHRTAEVDSTRTMVERVEAQFDLTPERLIGDTAYGTAPMLAWM
                     VEEKDIEPHVPVWDKTERKDDSLSSNDFHWSQDANEYRCPAGKPLRSEWRAFTQQRSRV
                     TKAKTVIYRSSQTDCATCPLKAKCCPNTPNRKIVRSIHEAARDVARRIAKTPEYLVSRC
                     ERKKVEMLFAHLKRIMKLDRLRLRGLTGATDEFTLAAMVQNLRRMAKLLPQGPPLTG"
                     /name="IS1182-like element ISCfr1 family transposase"
     gene            complement(4840..5976)
                     /locus_tag="UMY46_RS24435"
                     /old_locus_tag="UMY46_24490"
     CDS             complement(4840..5976)
                     /locus_tag="UMY46_RS24435"
                     /old_locus_tag="UMY46_24490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="WP_000080861.1"
                     /translation="MSQLSQLRSPAAVQAAIDEFVQLGRTKFLARHGYGKSRDFLVRDP
                     KTGTDCDSKAIAGVAFGKQFPEQGPLTADSFSGGETTVVPALTRLGFRIIRIGEDWSEE
                     EVLATVEDYFDMLRAEAAGEPYHKSEHNQALRQLLNGRSKSSVELKHQNISAVLDALGL
                     PYINGYKPRGNSQLLLRKSVHAYVLEHQQTVGALVDALEEVKLPGDKTYRAALVEPPAR
                     EVLVRTPASLRQRLPRKFDYAARDEANRKLGRAGEQWVIGYEQQRLTELGHPELFQRLD
                     WVSDTQGDGAGFDILSFEEDAHERFIEVKTTNGGVGSSFLVSHNELEFSKEAGDQFHLY
                     RVFQFRDGPRLFTLPGDLSQHVHLKPTDYRASFRSLVG"
                     /name="DUF3883 domain-containing protein"
     gene            complement(6027..6254)
                     /locus_tag="UMY46_RS24440"
                     /old_locus_tag="UMY46_24485"
     CDS             complement(6027..6254)
                     /locus_tag="UMY46_RS24440"
                     /old_locus_tag="UMY46_24485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000248278.1"
                     /translation="MVNSYSLSDDSGVMAAAAITHFLFGQAVFSYLNGWSVLIGPGTGL
                     DSTGCKYARDLMGLVAFTAFIVTFLFRGYS"
                     /name="hypothetical protein"
     gene            6278..6469
                     /locus_tag="UMY46_RS24445"
                     /old_locus_tag="UMY46_24480"
     CDS             6278..6469
                     /locus_tag="UMY46_RS24445"
                     /old_locus_tag="UMY46_24480"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000951934.1"
                     /translation="MAIALMGAGFSATDTSDAVNILYPITMTVQANKAWQASGLKKSFF
                     LPSHKKVRGGEKISYARL"
                     /name="hypothetical protein"
     gene            complement(6951..7493)
                     /locus_tag="UMY46_RS24450"
                     /old_locus_tag="UMY46_24475"
     CDS             complement(6951..7493)
                     /locus_tag="UMY46_RS24450"
                     /old_locus_tag="UMY46_24475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000587837.1"
                     /translation="MIIWINGPFGAGKTTLAKRLRDRRSKSLIFDPEEIGFVVKETVPM
                     PASGDYQDLPLWRGLTIAAVREIRRNYSQDIIIPMTLVHPDYLTEILDGVRRIDDQLLH
                     IFLTLNEDLLRHRIANQTMHPDPNRNAEIREWRLANVARCLAARERLPCTTRVLDSGAH
                     TSDELAAMVLDGIDGRT"
                     /name="AAA family ATPase"
     gene            complement(7506..8366)
                     /gene="aac(3)-IId"
                     /locus_tag="UMY46_RS24455"
                     /old_locus_tag="UMY46_24470"
     ARG             complement(7510..8366)
                     /name="aac(3)-IId"
                     /gene="aac(3)-IId"
                     /gene_name="aminoglycoside N-acetyltransferase AAC(3)-IId"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8599..9303
                     /locus_tag="UMY46_RS24460"
                     /old_locus_tag="UMY46_24465"
     CDS             8599..9303
                     /locus_tag="UMY46_RS24460"
                     /old_locus_tag="UMY46_24465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067858.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <9356..>11944
                     /locus_tag="UMY46_RS24465"
                     /old_locus_tag="UMY46_24460"
                     /pseudo=""
     CDS             <9356..>11944
                     /locus_tag="UMY46_RS24465"
                     /old_locus_tag="UMY46_24460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /name="Tn3-like element Tn3 family transposase"
     gene            complement(12002..13657)
                     /locus_tag="UMY46_RS24470"
                     /old_locus_tag="UMY46_24455"
     CDS             complement(12002..13657)
                     /locus_tag="UMY46_RS24470"
                     /old_locus_tag="UMY46_24455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mobilization protein A"
                     /protein_id="WP_322265843.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRVRRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGITWCAGGLV
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIGV"
                     /name="Mobilization protein A"
     gene            complement(15141..15290)
                     /locus_tag="UMY46_RS24475"
                     /old_locus_tag="UMY46_24450"
     CDS             complement(15141..15290)
                     /locus_tag="UMY46_RS24475"
                     /old_locus_tag="UMY46_24450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_020956931.1"
                     /translation="MKKVKVVFLFILIFLGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(15375..15632)
                     /locus_tag="UMY46_RS24480"
                     /old_locus_tag="UMY46_24445"
     CDS             complement(15375..15632)
                     /locus_tag="UMY46_RS24480"
                     /old_locus_tag="UMY46_24445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_041937905.1"
                     /translation="MGLKLNLTWFDKKTEEFIGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGGFDVEKPWVPLLQPYFKNKIEVDKYWYQISFDYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(15642..17330)
                     /locus_tag="UMY46_RS24485"
                     /old_locus_tag="UMY46_24440"
     CDS             complement(15642..17330)
                     /locus_tag="UMY46_RS24485"
                     /old_locus_tag="UMY46_24440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_020956933.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGVKDYGHDYHPAPKTEEIKGLGELKKAPKKTPKQGGGGRRDRWIGDKGRKVY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQIKGPDPKGRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            complement(17915..18433)
                     /locus_tag="UMY46_RS24490"
                     /old_locus_tag="UMY46_24435"
     CDS             complement(17915..18433)
                     /locus_tag="UMY46_RS24490"
                     /old_locus_tag="UMY46_24435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_020956924.1"
                     /translation="MQKVTDLYPPEIARHKLQNHFAGNTVMLELIQKLNKTSLCTFAAL
                     CDGNVVTTSGYNITADLCVNRASAVAHSLKQKYLPVTARTISTKADVGGAVKQAAFCID
                     EDDLARLKSEPEKMMKECERNLNSQKRTNAQKEMSRLYKEFGEDGILALLRNVAQSNGT
                     PPPGAHPAS"
                     /name="hypothetical protein"
     ARG             complement(1678..2534)
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     BGC             10642..19459
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          14460..15038
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.454"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgccgtatg atgtggaatg gaaacaggga gccatcgagg atgtaacgat gctgtttgac
       61 tatatcgcgg aaaattcatc cttgtgggat gcgcagaacg ttaccgatcg cgttctcact
      121 gcggcggaca aactggccga cttcccgcgc ctctatgaag tggactcacg ctatggcgag
      181 gacgttcgcc ggatcagtct gatgggacag catgtcctgt atgatgttga tgaccagacc
      241 aggaaagtcc gggttctggc cgtggttggc cagcgccaga atccccatac cgttcgctga
      301 taaccggtga cgggggcgca attcattgcg tggccgtcgc cggttggaca agcacagcgc
      361 gtcagcgttt tccccactgc caccaccggc gcggtgttcc ggccggtgtc tctgctgtct
      421 ccggtttgtg ttccagcagt ctcatggcct gcatttcctg ccgcagtccg gccacctcct
      481 ccctgagtgc ttttatctcc gcgatcaacg cgtcggaggc cgttttttca gtctcatccg
      541 gcagtctcaa cccgtcccgc tcgtgagtct caccctgtct taactcaccg tatacccgga
      601 taagctcgct ggtatccacc acccgaccac catcagcttc cgtacggtat gatacgcggc
      661 ctttcgccat atcccgatac agggaactcc gggctttccc cgtcagttcc gtcgcctgtc
      721 tcacagtcac ccacgccatt gtctcactcc gctatttttg agacagtata cccgacaggc
      781 gcacaccatg cccggaagga aagaatcatg acaaaacagg aaaaaactgc cctcaatatg
      841 gctaaattca ttaaggacca gtcgctgctg ttgctcgaga aactgaacga gctggatatg
      901 gataccccgg ccgacatgtg cgagcggctg cacgaggatg cggaaacact ctggcaggtg
      961 atgcgggata agctcgggga ggaataacag caccggcatg gccggtgctg gcgtttattt
     1021 tttgccgaac ggccaccacc ggcgggcgga tttgtcctcc ggcagttcag gcaccggcac
     1081 gttaaaatag cggctgttat attcccgcat cagctccgct ttcagcttct cgttcaccgc
     1141 gctttccccg tgccgctcgc tgaccacctc aatcatcgcg ctaatctgct ccggtgagca
     1201 cttcccggca tcaaccacct gcacaccgtt ctcgatggcg aaccgctcca ccttgcgata
     1261 gaggtaatca cacagcttca ttcctgcggg tttgtcccgt tcccattgcg gattttcacc
     1321 ggtgaaaaag tatgtggctt tttcgtcgct gttgagccgc tcgtcataca tcccgatgga
     1381 tttcatcatc gccagatgct gggtccggtc gacaaaacag aaaacatacg ccccggtctg
     1441 ccaggcgagc accaccatat cttcaagatg ctcgctggtc ggcatgatgc agcgctcgcc
     1501 gtcccggtcc tccacatctt caataagggg tctgacgctc agtggaacga aaactcacgt
     1561 taagggattt tggtcatgag attatcaaaa aggatcttca cctagatcct tttaaattaa
     1621 aaatgaagtt ttaaatcaat ctaaagtata tatgagtaaa cttggtctga cagttaccaa
     1681 tgcttaatca gtgaggcacc tatctcagcg atctgtctat ttcgttcatc catagttgcc
     1741 tgactccccg tcgtgtagat aactacgata cgggagggct taccatctgg ccccagtgct
     1801 gcaatgatac cgcgagaccc acgctcaccg gctccagatt tatcagcaat aaaccagcca
     1861 gccggaaggg ccgagcgcag aagtggtcct gcaactttat ccgcctccat ccagtctatt
     1921 aattgttgcc gggaagctag agtaagtagt tcgccagtta atagtttgcg caacgttgtt
     1981 gccattgctg caggcatcgt ggtgtcacgc tcgtcgtttg gtatggcttc attcagctcc
     2041 ggttcccaac gatcaaggcg agttacatga tcccccatgt tgtgcaaaaa agcggttagc
     2101 tccttcggtc ctccgatcgt tgtcagaagt aagttggcag cagtgttatc actcatggtt
     2161 atggcagcac tgcataattc tcttactgtc atgccatccg taagatgctt ttctgtgact
     2221 ggtgagtact caaccaagtc attctgagaa tagtgtatgc ggcgaccgag ttgctcttgc
     2281 ccggcgtcaa cacgggataa taccgcacca catagcagaa ctttaaaagt gctcatcatt
     2341 ggaaaacgtt cttcggggcg aaaactctca aggatcttac cgctgttgag atccagttcg
     2401 atgtaaccca ctcgtgcacc caactgatct tcagcatctt ttactttcac cagcgtttct
     2461 gggtgagcaa aaacaggaag gcaaaatgcc gcaaaaaagg gaataagggc gacacgaaaa
     2521 tgttgaatac tcatactctt cctttttcaa tattattgaa gcatttacca gggttattgt
     2581 ctcatgagcg gatacatatt tgaatgtatt tagaaaaata aacaaatagg ggttccgcgc
     2641 acatttcccc gaaaagtgcc acctgacgtc taagaaacca ttattatcat gacattaacc
     2701 tataaaaata ggcgtatcac gaggcctgtg ggaggaaaat aaagtgtcat cctaactaca
     2761 ggaccctgca acgtagcaat tcctgcaaaa atccatttaa aacaatgact tatttcaatt
     2821 ctgccatctg caagcgtttt gtggggatgg aggccggaat cattaaagta tcatcctaat
     2881 tttcgctcaa ccttggaaaa tgctgagaat cgtaaaaata aagtttcatc ctttccgcta
     2941 ctagttcaag gctttcttcc ggccgccggc aacaacgctg cttggctgag gcgatccact
     3001 tgcgctaccg ctcactgatc agatcgaact tgaactcgac gagcagccaa ccatcaggcc
     3061 gagcgtgatc gccaaaaaaa acggatcatg cgaaatcctt cgttgagttt ggcgcgggtt
     3121 ttagcaaatc agctggcccg cgatccggtt gagagtgatc cgaagcggtc cttgacgacc
     3181 ggcacaaatc ggccgattct gttgaaaaag tagctttagc ggcagcctgc cgatcaggtg
     3241 tgcctgctgt cgaagtggct gcaagccact tcaagttgcc ttccggcgtt tcactgagcg
     3301 tccttgctca ggtttaaggg ttaatttgag ggtttctgct cgtagcaggc atacctatcc
     3361 cgtcagcggt ggcccttgag gcaaaagctt ggccatgcgg cgcaggttct gcaccatcgc
     3421 agccaaggtg aattcgtcag tggcacccgt taggccacgc agtcgtaaac ggtcgagttt
     3481 catgatccgt ttgaggtggg cgaaaagcat ctccaccttc tttcgttcgc agcgagagac
     3541 gaggtactcc ggtgtcttgg cgatgcgtcg agccacgtcg cgggcagcct catggatgct
     3601 gcggacgatc ttccgattcg gcgtgttggg gcagcatttc gctttcaacg ggcaggtggc
     3661 gcagtcggtt tggctggagc ggtaaatgac ggttttggcc ttagttaccc gcgacctttg
     3721 ctgggtgaag gcgcgccatt cactgcgtag cggtttgccg gctgggcagc gatattcatt
     3781 ggcgtcctga ctccagtgaa agtcgttact ggagaggctg tcgtccttgc gctcggtctt
     3841 gtcccacacc ggcacatgcg gttcgatgtc cttttcttcg accatccagg ccagcatcgg
     3901 ggcggtgcca taagcggtat cgccgataag gcgttccggt gtgagatcga actgcgcctc
     3961 gacacgctcg accatcgtcc tagtcgaatc gacttcggcg gtacggtgcg ccggggtagc
     4021 ttccacgtcc atgatcacac cgtgctcagt gtcgatcagg taattcgtgg agtaggcaaa
     4081 aaaggccggg ccacctggcg ctgctgtcca acgggactga ggatcagtga gcgaaatttt
     4141 cttgggaaga gcctcagcca gcgcctcttc atcaagggct tcgaggtact cgcgcactgc
     4201 gcggctgctg agctttggat cgttccaatc gacctcatct cccgccaccc cacgttgccg
     4261 gctggcatcc gccttaatga tgctggcgtc gacggcgaaa ccttcaccct tgactaggcc
     4321 ggctgccatg cagcgccgca gcacctcatt gaataaccag cggaatagat cgctgtcacg
     4381 aaaacgccca tggcgattct tcgagaaggt cgagtgattg gggacttcgt cttccagacc
     4441 caaccggcag aaccagcgat aggccaggtt caggtgcacc tcttcgcaca atcgccgctc
     4501 ggaacgaatg ccatagcagt agccgacgac cagcatgcgc accatcaact ccgggtcaat
     4561 cgagggacgc ccgatggggc tatagaaatc tgccaggtag gcacgtagat cactgagatc
     4621 caagcactgg tcgatgctgc gcaggagatg ttgggccggg acgtgatctt ccagattgaa
     4681 cgagtagaac aggcgctgct gtcctcccgg taactgtccc atcatgctgt tcgcccccac
     4741 gctcgctgac aaagcaattt tgccaacggc atggggaggc cgctactttt tcaacagaat
     4801 cggccgcaca cagccattcg gctcaacaga accctgcctt taccccacca aactccggaa
     4861 actcgcccgg tagtccgtcg gcttgagatg cacatgttgg ctgaggtcgc cgggtagcgt
     4921 gaacaggcgc ggaccgtccc gaaactggaa cacgcgatac agatggaatt gatcgcccgc
     4981 ctccttggag aattcgagtt cgttgtggct gaccaagaaa gacgagccta ccccgccatt
     5041 ggtggttttc acctcgatga agcgctcatg ggcgtcctct tcgaacgaca ggatgtcgaa
     5101 ccccgcaccg tctccctggg tgtcggacac ccaatccagc cgctgaaaaa gctctgggtg
     5161 gccgagctcg gtcaggcgtt gctgttcgta gccaatcacc cactgctccc ctgcccggcc
     5221 cagcttgcgg ttggcttcat cgcgagcggc ataatcgaac tttcgcggta ggcgttgccg
     5281 tagagatgcc ggggtacgca caagcacttc acgggcgggt ggttctacca aagccgctcg
     5341 gtaggttttg tcacccggaa gttttacctc ctccagggca tcgacaagag cgccgaccgt
     5401 ctgctgatgt tccagaacgt aggcgtgtac ggatttacgc agcagcagtt ggctgttgcc
     5461 gcgtggcttg tagccgttga tatagggcag gcccagggca tcgagtacgg cgctaatgtt
     5521 ctggtgcttg agctcgactg aagacttgct gcgaccgttc agcagttggc gcagtgcctg
     5581 gttgtgctcg gacttgtggt acggctcccc agccgcctcg gcacgcagca tgtcgaaata
     5641 gtcttcgacc gtggccagga cctcttcttc ggaccagtct tcgccgatgc gaatgatgcg
     5701 aaacccgagc cgcgtcagcg ccggaacgac ggtcgtctcg ccaccggaga agctgtcagc
     5761 agtgagcggg ccctgctcgg gaaattgctt gccgaaggcc acaccggcga tggccttgga
     5821 atcgcaatcg gtgccggtct tcggatcacg taccaggaag tcgcgggact tgccgtagcc
     5881 gtggcgcgcc aggaatttcg tgcggcccag ttgcacgaac tcatcgatgg cagcctgcac
     5941 ggcggcgggg cttcgaagct gggagagttg agacacaggg tccttcctta ctgtcatggt
     6001 gtgccgggaa ccgccgagcc acgagattat gagtagcccc tgaacagaaa cgtcacgata
     6061 aaagccgtga acgccaccag gcccattaaa tcccttgcgt atttgcagcc cgtgctgtcc
     6121 aaacctgtac caggtccgat caacacgctc caaccattga ggtacgaaaa caccgcctga
     6181 ccgaacaaaa aatgcgtgat agccgccgca gccatgacgc cggaatcgtc agacaggctg
     6241 tagctgttga ccattgccct gtacgcctgc atctgaaatg gctattgccc tgatgggagc
     6301 cggcttttca gccaccgaca ccagcgatgc cgtcaatatt ctttacccga taaccatgac
     6361 cgtacaagct aacaaggcct ggcaagccag cggacttaaa aagtcttttt ttctaccatc
     6421 ccacaaaaaa gttcgtggtg gagaaaagat aagctatgca aggctttagg agacgtggtt
     6481 tttcaggatg acgaagaacg attcggcgct aggtgcaaca taggtgcatc gcacgagcgc
     6541 taggaacggc gaaaaaaggc ggacgtggcg aaatcggtag acgcagcaga ctttaaaatt
     6601 ggagtgcccg cggggaaatc cgcggagtag aaccgctcaa agtcggggaa cgctaacggg
     6661 caatacccta agccaatccc gagccaagcc ccttcggggg aaggtgtaga gactggacgg
     6721 gcggcgccta aagccttcgg gcaatggcga agggacagtc cagaccacga acgtcatcag
     6781 acggcggcga aagtcgaggt ggtacgaaaa tctgcttctc tgtgagagta cgggttcgag
     6841 tcccgtcgtc cgcaccacaa agccaaacat ccctgcgatg atcgacctct gggcgtttgg
     6901 tcgtgagccc gccaccctcg cgctacgctt tgcgcaggcg tcgaaggcga tcaggtgcgc
     6961 ccatcgattc cgtcgagcac catcgctgcg agttcatcgc tggtgtgtgc accactatcg
     7021 agaacacggg ttgtgcatgg aagccgttcc cttgcggcca agcatcgggc gacattcgct
     7081 aatcgccact ctcgaatctc cgcatttcga ttcgggtcag gatgcatggt ctggttcgcg
     7141 atccggtgac gcaataggtc ctcgttgagc gtcagaaaga tgtgcagcag ctgatcgtcg
     7201 atccgcctta ccccgtcgag tatctcagtc agatagtccg ggtgcacgag cgtcattggg
     7261 atgatgatgt cctgcgagta attccttcga atctccctga ccgccgcgat cgtaagtccc
     7321 ctccacaagg ggagatcctg atagtctccg ctcgctggca tggggaccgt ttctttcacc
     7381 acgaacccga tttcctcggg gtcaaagatc agcgatttgg aacgccgatc gcgcagccgc
     7441 ttagcgagcg tcgtctttcc ggcgccgaaa ggtccgttga tccagattat cattgtcgac
     7501 ggcctctaac ctgaaggctc gcaagagcgc tcgacggcct cgtgcggagg cacgatcgga
     7561 gtggttccga aatgcttctc aagataggtg acgccgaacg tcacgatgtc ctgcgcgtcg
     7621 aacaggtagc actgagcaaa gcccacgaca ccttctcgat ggcgaccgag cttcacgtaa
     7681 gcatttgcta tagtttcaac cgcatccggc tttccttcga tagcaaagca atcgagaatg
     7741 ccgtttgaat cgtaatccga tgccgttttc caggcgactt caccgtctct tccaagcatc
     7801 ggcatctcat acgtcaccca ccgtttgttg gggatatcgg caaccgcctc ggcgtagtgc
     7861 aatgcggtaa cggagtttag cggcgcaccc aacagcaggg ccttcccgcc aaggcgaacg
     7921 aaccgctcga cgggcgatcc ttcccccaag gcgtgaccga gttcgtgagg ctccgtcagc
     7981 gtttcagcca gcggaccaac cgcgaccatc gatgcatcgg ggtgcgcgct gcgccgcgcg
     8041 ccgggggctt gaaccagaaa ttgattcagc aggccgaacc cacggtaagt cccggctgtt
     8101 gcgggatcga acggcagcca ggtacggcgg gcttcgtcat ccagccgagc gccattcaga
     8161 gtctcctcgt agggtgatcg gtcccacgac gcgtatccca tcacagtgcc agtcggccca
     8221 accgcggagc gtaacgcggc aacgaccgtc tccgctcctc cttcgaccgg accaatcgct
     8281 ttaagtgagg catgcaccat caagaggtca ccggtttgga ctccgagttt ttgaagcgcc
     8341 tccgttattg ccttccgcgt atgcatcgcg atatctcctc taaactgcaa aacactatac
     8401 ggggtctgac gctcagtgga acgaaaactc acgttaaggg attttggtca tgagattatc
     8461 aaaaaggatc ttcacctaga tccttttaaa ttaaaaatga agttttaaat caatctaaag
     8521 tatatatgag taaacggcac tgttgcaaat agtcggtggt gataaactta tcatcccctt
     8581 ttgctgatgg agctgcacat gaacccattc aaaggccggc attttcagcg tgacatcatt
     8641 ctgtgggccg tacgctggta ctgcaaatac ggcatcagtt accgtgagct gcaggagatg
     8701 ctggctgaac gcggagtgaa tgtcgatcac tccacgattt accgctgggt tcagcgttat
     8761 gcgcctgaaa tggaaaaacg gctgcgctgg tactggcgta acccttccga tctttgcccg
     8821 tggcacatgg atgaaaccta cgtgaaggtc aatggccgct gggcgtatct gtaccgggcc
     8881 gtcgacagcc ggggccgcac tgtcgatttt tatctctcct cccgtcgtaa cagcaaagct
     8941 gcataccggt ttctgggtaa aatcctcaac aacgtgaaga agtggcagat cccgcgattc
     9001 atcaacacgg ataaagcgcc cgcctatggt cgcgcgcttg ctctgctcaa acgcgaaggc
     9061 cggtgcccgt ctgacgttga acaccgacag attaagtacc ggaacaacgt gattgaatgc
     9121 gatcatggca aactgaaacg gataatcaac gccacgctgg gatttaaatc catgaagacg
     9181 gcttacgcca ccatcaaagg tattgaggtg atgcgtgcac tacgcaaagg ccaggcctca
     9241 gcattttatt atggtgatcc cctgggcgaa atgcgcctgg taagcagagt ttttgaaatg
     9301 taaggccttt gaataagaca aaaggctgcc tcatcgctaa ctttgcaaca gtgccctttt
     9361 atatacccgg agctggataa gcaacgaacg tcctggcctg cttttcgatc tggcgacagg
     9421 gtggcttatg caacatcgta ttattctccc cggagccact acgctgaccc ggttgatttc
     9481 agaggtaagg gaaaaggcga cgttgcgcct gtggaacaaa ctggcactga taccgtcagc
     9541 cgaacagcgt tcacagctgg agatgctgct ggggccaact gattgcagcc gcctgtcttt
     9601 actggaatca ctgaaaaagg gccctgtgac catcagtggt ccggcgttta atgaagcaat
     9661 tgaacgctgg aaaactctga acgattttgg cctgcatgct gaaaacctga gtacactccc
     9721 ggctgtgcgc ctgaaaaatc tcgcacgtta tgctggtatg acttcggtgt tcaatattgc
     9781 caggatgtca ccgcagaaaa ggatggcggt tctggttgcc tttgtccttg catgggaaac
     9841 gctggcgctg gatgatgcat tggacgttct ggacgccatg ctggccgtta tcatccgtga
     9901 cgccagaaag attgggcaga aaaaacggct ccgctcgctg aaggatctgg ataaatctgc
     9961 attggcgctc gccagcgcat gttcgtacct gctgaaagaa gaaacaccgg acgaatcgat
    10021 tcgtgctgag gtgttcagct acatcccaag gcaaaagctg gctgaaatca tcacgcttgt
    10081 ccgtgaaatt gcccggccct cagacgataa ttttcatgaa gaaatggtgg agcagtacgg
    10141 gcgcgttcgt cgtttcctgc cccatctgct gaataccgtt aaattttcat ccgcacctgc
    10201 cggggttacc actctgaatg cctgtgacta cctcagccgg gagttcagct cacggcggca
    10261 gttttttgac gacgcaccaa cggaaattat cagtcggtca tggaaacggc tggtgattaa
    10321 caaggaaaaa catatcaccc gcaggggata cacgctctgc tttctcagta aactgcagga
    10381 tagtctgagg cggagggatg tctacgttac cggcagtaac cggtggggag atcctcgtgc
    10441 aagattacta cagggtgctg actggcaggc aaaccggatt aaggtttatc gttctttggg
    10501 gcacccgaca gacccgcagg aagcaataaa atctctgggt catcagcttg atagtcgtta
    10561 cagacaggtt gctgcacgtc tttgcgaaaa tgaggctgtc gaactcgatg tttctggccc
    10621 gaagccccgg ttgacaattt ctcccctcgc cagtcttgat gagccggaca gtctgaaacg
    10681 actgagcaaa atgatcagtg atctactccc tccggtggat ttaacggagt tgctgctcga
    10741 aattaacgcc cataccggat ttgctgatga gtttttccat gctagtgaag ccagtgccag
    10801 agttgatgat ctgcccgtca gcatcagcgc cgtgctgatg gctgaagcct gcaatatcgg
    10861 tctggaacca ctgatcagat caaatgttcc tgcactgacc cgacaccggc tgaactggac
    10921 aaaagcgaac tatctgcggg ctgaaactat caccagcgct aatgccagac tggttgattt
    10981 tcaggcaacg ctgccactgg cacagatatg gggtggagga gaagtggcat ctgcagatgg
    11041 aatgcgcttt gttacgccag tcagaacaat caatgccgga ccgaaccgca aatactttgg
    11101 taataacaga gggatcacct ggtacaactt tgtgtccgat cagtattccg gctttcatgg
    11161 catcgttata ccggggacgc tgagggactc tatctttgtg ctggaaggtc ttctggaaca
    11221 ggagaccggg ctgaatccaa ccgaaattat gaccgataca gcaggtgcca gcgaacttgt
    11281 ctttggcctt ttctggctgc tgggatacca gttttctcca cgcctggctg atgccggtgc
    11341 ttcggttttc tggcgaatgg accatgatgc cgactatggc gtgctgaatg atattgccag
    11401 agggcaatca gatccccgaa aaatagtcct tcagtgggac gaaatgatcc ggaccgctgg
    11461 ctccctgaag ctgggcaaag tacaggtttc agtgctggtc cgttcattgc tgaaaagtga
    11521 acgtccttcc ggactgactc aggcaatcat tgaagtgggg cgcatcaaca aaacgctgta
    11581 tctgcttaat tatattgatg atgaagatta ccgccggcgc attctgaccc agcttaatcg
    11641 gggagaaagt cgccatgccg ttgccagagc catctgtcac ggtcaaaaag gtgagataag
    11701 aaaacgatat accgacggtc aggaagatca actgggcaca ctggggctgg tcactaacgc
    11761 cgtcgtgtta tggaacacta tttatatgca ggcagccctg gatcatctcc gggcgcaggg
    11821 tgaaacactg aatgatgaag atatcgcacg cctctccccg ctttgccacg gacatatcaa
    11881 tatgctcggc cattattcct tcacgctggc agaactggtg accaaaggac atctgagacc
    11941 attaaaagag gcgtcagagg cagaaaacgt tgcttaacgt gagttttcgt tccactgagc
    12001 gtcagacccc gatctccccg gtctggcccg ccgcccactg cgcggactcc tggctggccg
    12061 cgcgatagaa ccagcggatc ggcgtgttat ccagtaccgt ggttttcaca aaatcagcgg
    12121 gcagatcctg gccgcactgg ccgaagtcgc ccagcgactg gtgcgcgagc agcaggttgc
    12181 agtcccggct gcgcagcgtc cccagcgcgt tcagcacgta tttcgacagc agatatttaa
    12241 tctcatcgag catgatgctc gcgtgcggcc acctccggaa ctcatcccgc gcaatgatga
    12301 tttgcgcgca gcgggcaaac aacatcttct gcacccggat caccgcctca tcgtccatcg
    12361 agccgatgac gtacaggcag ccgccgccgt tgattatccc cgccacgtcg atgccgctgt
    12421 ccgtctgcag gacgctcagg tcggccacgt tctccagctt ggtgatcagc cccttcacgt
    12481 cctttttcag ggcctccggc agcgcgtatg ccgccgccag cacctgctga atgtttgccc
    12541 cctgcgggaa ctgctccgca atcagcttcg ccgctttctg ctcgctgatg cggtagtggt
    12601 ccgccacgtc gccggtctca ctcaggttaa acccggcaac cagcagattc ttcagggcgt
    12661 actggtcgag atcgcggaac agattcagct gcgccggttt ccccggccgc agatccagca
    12721 gggtgaagtc cgggcagtgc gcccggaaga cgtgcggtgc ccacgcgtcc cctttcgggt
    12781 cgaagtacac caccgcgtcc ccgaaatcgc gtacgcagcg aatgagcgcg ttggtggcca
    12841 tcacgctctt gccgctcccg ggcaggccga ggatctgaat gttggtcttg cgccaggtat
    12901 cacgcgggac cagcaccggc tggccctgct catccttacc cagaaacacc gcctgctgtt
    12961 tccgggcctg ctccgtggaa aaatcggcca gcgcgttaac cggtaccggc tccccgaaat
    13021 gcaggtggcg gacgtcggtc atttcaccgg tccgctggct gctgcgccgg ctctcctggt
    13081 tcagtttcgc gttcaccgcc tcgtcagcgg ccgcaaaatg accgtcaagc agcaggaacg
    13141 ccagcagccg cgccaacaca atcccgacaa ccagcccgcc cgcgcaccag gtaatcccga
    13201 acaggttagc cggctgcagc aggtaataat ctgcgttcgc gtagaggtcc ggacgcagga
    13261 cggtttctcc ccagctctcg ataaacacgg cgacaacaag cccccccaga agggccagac
    13321 cggcagcgcc ggtcagccag tacgcgtagt tccagacatg ccgccgaacc ctgaccatcc
    13381 gcccgggcga atccagcgag gccagcaccg aaaatggcgc agtccggtta ttatcgcgct
    13441 tatagcgatc ggcatactcc cgccgctcct tatgactcag ccccacaaaa cgcatccgtc
    13501 cggcccagag ttcagccaga ccgaaaaaca ggccgataac cagaaaagcc ccggccagac
    13561 cgtaatactc ccggtacagc cagctgaccc acgggtaaat ctgccgggcc agctccggga
    13621 tatgccactg ccaggcaagc gaatccgtat taaacatgca atctctctcc ttcagacgac
    13681 gggtttaccg gcgtgttgtg cagcccctgc tgcacaagcc gcggacatgc cccaaggcat
    13741 ggcggcggcg gtcacgtccg tggtgattgc gttcagcttt caccgcggag gccagcctct
    13801 ttccgcccca tgcggaaaag gcgcagcccc ggaggaacaa cgagcacgcc ccagcgtgtg
    13861 agaggaaaag gcggcacccc agtgcggtct tttccggtgt tccggccccc gtcagagttc
    13921 gccatagcga gcggctgacc acccgcaaaa tcaggagcag ctttgctgct tcgtcaggtg
    13981 cgttcagcac cgtggatttt tgtgggtggt caggcgtgag cctgacgggg gccgggtgaa
    14041 tttctggcgt gaccggcgtc cagccggaca gagccagaaa gagggggaaa gaccgtgcgt
    14101 cggtggcgtc cagccagcgt aagcagggga tttccccctg aagtcagcca cgccccagcg
    14161 gggatgactt gcatttctcc gcaaggagaa aaaagcaaca gagataggtt aacttaaaat
    14221 gttcagcgaa aaaccgacat ggttcaccta ttcggataat tgatcgtcag ggaatagaaa
    14281 gacttaatca ggggacaata tcccacatca gcgcgtccgg tgaccgtctt gcaggtgccg
    14341 gggaaattgc gcctcctcgc tcactcggtc gctacgctcc gggcgtgaga ctgcggcggg
    14401 cgctgcggac acatacaaag ttacccacag attccgtgga taagcagggg actaacatgt
    14461 gaggcaaaac ggcagggccg cgccggtggc gtttttccat aggctccgcc ctcctgccag
    14521 agttcacata aacagacgct ttttcggtgc atctgtggga gccgtgaggc tcaaccatga
    14581 atctgacagt acgggcgaaa cccgacagga cttaaagatc cccaccgttt ccggtaggtc
    14641 gctccctctt gcgctctcct gttccgaccc tgccgtttac cggatacctg tccgcctttc
    14701 tcccttgcgg gaagtgtggc gctttctcat agctcacaca ctggtatctc ggctcggtgt
    14761 aggtcgttcg ctccaagctg ggctgtaagc aagaactccc cgttcagccc gactgctgcg
    14821 ccttatccgg taactgttca cttgagtcca acccggaaaa gcacgcaaaa cgccactggc
    14881 agcagccatt ggtaactggg agttcgcaga ggatttgttt agctaaacac gcggttgctc
    14941 ttgaagtgtg caccaaagtc cggctacact ggaaggacag atttggttgc tgtgctctgc
    15001 gaaagccagt taccacggtt aagcagttcc ccaactgact taaccttcga tcaaaccacc
    15061 tccccaggtg gttttttcgt ttacagggca aaagattacg cgcagaaaaa aaggatctca
    15121 agaagatcct ttgatctttt ctactgaacc gcgatccccg tcagttcaga ggaggacgat
    15181 ggtgccaccg ttccaccctg aacatcccgg atatagtttg cctgacatgc gaccagaaga
    15241 aagcctaaaa aaatcaatat aaaaagaaaa acaaccttta cctttttcat ataccttccc
    15301 tgtatttaaa aaccccggca ttcatccctg aacaccggaa gtctgtattt caaatcatcc
    15361 ttgataattt tttgttacca gttaccgtcc cgataatcaa atgaaatttg ataccagtac
    15421 ttatcgactt caattttatt tttaaaatat ggctgcaaca acggaaccca tggtttctca
    15481 acatcaaacc cgccattgtt aatattatcc tttaaaggca ttccaaggct ttcaatgaca
    15541 gaaccatcat caccaaagtc tttagaatac tcctcaccaa taaattcctc agtcttctta
    15601 tcaaaccagg ttaaatttaa tttaagcccc atacttacct ctcaaagata ttttttaatg
    15661 tttcgtcctt tcggatccgg acctttaatt tgcttacccg tttttggatc aaatgccccg
    15721 aggtgttcgc catcactggc acgataccct tcaagctcac cgtgctggga gtcccattca
    15781 taaaccttac ggcctttatc accaatccaa cggtcacgtc taccaccacc accttgttta
    15841 ggtgtttttt taggtgcttt ttttaattcc cccaacccct tgatttcttc ggtcttcgga
    15901 gcgggatgat aatcatgacc gtaatcttta actcccttgc gaggcttgtt cttttcctca
    15961 tttaacttat tttctgcatc cttcgctttt ttctcctttt gtttccggct ctccatcgcc
    16021 ccggtaagtg cagccttatc tctggataag gattcattca ttgcgtttaa agatgcctga
    16081 gccgctttta atttctcatt ctgattctga atatccttat caagatagcg aacctgatcc
    16141 tgccacccgg agccatattc atgaggcggg ttataagtca caaaatcatc tttatttgcc
    16201 tctgcctctt ttaccttttt atcggcttcc tgaacagcag cccttgcacc ggggagcgcc
    16261 ttctctgtcg atgcaatgcg gctgtttaag gtcgcaatat ttttatcttc ggcatccagc
    16321 tcagctttcg ctttatcata gtctcttttc agcccctctt ccggatgagc ggcgtcccat
    16381 gcctgctggc gacgcttttc ttcctcctga cgctgtttta cctgtgccgg ggtaagaaca
    16441 tctgtcaccg acacataaac cggcttctgt cctgtctctt tcgggaaacg aataacggcc
    16501 tcacgggagt taccaccggc tgtaaaacca gccggacgtg aatcaccttt ttcagcaaca
    16561 atgccttttg gcggggcttt cgctgtcgga acacctttcg gtacgctcac ctgcagagac
    16621 gggagacccg gaatcgacac actgaatacc cccggacgtt ttgtcggttt cgcatccacc
    16681 acagggacac tcattggccg acctgcgaca accgcaatat gctgccgctc atccttcacc
    16741 acatccacaa cccgttgtct gacacgaacc gtcgcctggt ccagtggtaa agtacttgcc
    16801 ggagtctccg tcaccgcatc ggccggtaat gacgtcataa tttttgacat cattttcgga
    16861 tcatcttttg caatctcaga aggcagcaca ccgtagatcg caatccccca cagaccaaac
    16921 ttaaacggcc ccttcagggc agccagcaca tcagcaacgg cggccgacaa cgcatcgccg
    16981 gaaactgata aagccagtcc ttcagccccc ggagtagcca gggcaggcag accgaaagcc
    17041 atcgcagtgg ccgaagactg tccgccacca gagctaccgc tatgattgcc gctgttacca
    17101 ccattaccac cgggtttact cccgccgtta ccaaactccc ccggattata gttatgaata
    17161 tctccattcg gcgtatgcgt cgtaccccag cccggcccgc tgtttggatc cgtaccacca
    17221 cctgatgaag ggccaccttt accagacgta ccgttcacat tcccactggc ctgaccacca
    17281 ttatgtccca gacctgaatt acccggacct cgaccgtctc caccactcat atcgttttcc
    17341 tctttgacat ttaaaacaat aaattaaaac caatatactg tatatataca cagtataatt
    17401 gttaccttac tcctccagtt ttcaggtgtc aatatatgag attagttctc atcttcaggc
    17461 acaaaaaagc gcccggagcc gcctgtaagc agatcgcgtc ttttcccgaa aatttctcat
    17521 ggcaacaaat tttattattt gagatattca tcacacttac ttttatattg gtatagatgt
    17581 acctgaaagc gaaatggcat gaggagagta cctgcggtta aactgttcag gaatcggaga
    17641 caacccggag gccaccatga cgcacctgaa gaaaagcgcc tggcggacgc ctttgtcgct
    17701 caggcactgg ccatgggcct gaaaggggtt cgaggtccaa ccgtacgaaa atgtacggta
    17761 agagtgaaat tctcgtccga aagaaggaaa agcaaaactg gtaacgccac cgccggtaga
    17821 agggaactat ctgcaccgcg attagctgac agatcaagag ctggcggcat ccagaaaacc
    17881 ttaaaaataa agccccttag gggctttact ggtatcaact tgcagggtgt gcgcctggcg
    17941 gcggtgtacc gttcgactgg gcaacattgc gtaacagcgc cagtatgccg tcttcaccaa
    18001 actccttgta caaccggctc atttccttct gagcattggt gcgcttctgg ctgttcaggt
    18061 tacgttcgca ctctttcatc atcttttccg gctctgattt cagccttgca agatcgtcct
    18121 catcgataca gaaagccgcc tgctttaccg caccacctac atcagccttt gtcgaaatcg
    18181 ttctggccgt aactggcaga tatttttgct taagcgaatg ggccacggct gacgcacggt
    18241 taacacatag atcggccgtg atgttatagc cggaagtggt cactacgttg ccgtcacaga
    18301 gcgccgcaaa agtacacagg ctggttttat ttagtttctg gattaactcc agcataacgg
    18361 tattaccggc gaagtgattc tggagcttat ggcgagcaat ttcaggagga tacagatcag
    18421 ttactttttg catttatagc acctgtttac agaggataaa taacaggtga cggtgtccgg
    18481 atgagcattc gcacatcaaa aaactgtgaa aaatgcctgg caagtcggta ccaagttact
    18541 acataatgca gcaccacttg acaaacgccc taatcgggcg tttgttgatc aggtaagatt
    18601 cagttttcac gaactgagtc accggcagct atcagaatcc ttagtttctc aggccgaaga
    18661 tctgatagct gcctcgtttt tcactgacaa cctcacgatc atcagaatcc cttattctac
    18721 cttattccat aagcgcacac atagcttttt tgctgatctt tcgcgcttga tttacaagga
    18781 aattacctgt ctggtcgatg aaattagcaa cagcgctatc agatgacgct aatgttaaac
    18841 tcatgtttaa acatacagcg aaaagttgac gcaaaaatcg tcagctgaat gcctcataac
    18901 cagccattta ccataaaacc cgttgcccgc accgcccgag aagccctcag agcgtttccg
    18961 gcggctacgg gataaaacag gcaacaaatc acccggaaaa ccgccggaaa cgcgcccggt
    19021 aaactttatc ctaatgcatg cctatgcacg caactgcata gcatatgttt tgacgtaaaa
    19081 tggatgccgt aagccctttt tttacagact ttctgcttca tcagcctgac tgacacgacc
    19141 atattctttc agaccgcccc ctgctaaact tcttcatatc accgcattaa tccgggagcc
    19201 tccgcaatga gcaacactac acactacgaa aacgccaact tcctgcggga actggctgaa
    19261 aacctgcccc gcatactgcc ggaaagtgac ccggacaaag ctgcgttgtt gcaacgcctg
    19321 gctaacgaag aactggccca ggcagagtat gaagatcagg ttcgcgccaa agtaaccgcc
    19381 gcccgtgctg acacgcgtcc gggcatgacc acggaacaac tccgccagcg cctgcatggc
    19441 cgttatcagg aactgcgcg
//
