LOCUS       NZ_CP138668            20721 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus aureus strain DA70900 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP138668
VERSION     NZ_CP138668.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38170757
            Assembly: GCF_036670115.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20721)
  AUTHORS   Heidarian,S., Guliaev,A., Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     High prevalence of heteroresistance in Staphylococcus aureus is
            caused by a multitude of mutations in core genes
  JOURNAL   PLoS Biol 22 (1), e3002457 (2024)
   PUBMED   38175839
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20721)
  AUTHORS   Heidarian,S., Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2023) Medical Biochemistry and Microbiology,
            Uppsala University, Husargatan 3, Uppsala 75123, Sweden
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler or Flye + medaka + Polypolish, SPAdes
            v. v0.4.8, v2.9.1, v1.6.0, v0.5.0, 3.15.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 546.830678571429x
            Sequencing Technology             :: DNBseq and Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_036670115.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 15:34:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,760
            CDSs (total)                      :: 2,679
            Genes (coding)                    :: 2,599
            CDSs (with protein)               :: 2,599
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 55 of 80
            Pseudo Genes (incomplete)         :: 35 of 80
            Pseudo Genes (internal stop)      :: 17 of 80
            Pseudo Genes (multiple problems)  :: 23 of 80
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP138668.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20721
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="DA70900"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="Denmark"
     gene            166..842
                     /locus_tag="SGW60_RS13685"
                     /pseudo=""
     CDS             166..842
                     /locus_tag="SGW60_RS13685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <853..1135
                     /locus_tag="SGW60_RS13690"
                     /pseudo=""
     CDS             <853..1135
                     /locus_tag="SGW60_RS13690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2346..2963
                     /gene="cadD"
                     /locus_tag="SGW60_RS13695"
     ARG             2347..2960
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2982..3329
                     /locus_tag="SGW60_RS13700"
     CDS             2982..3329
                     /locus_tag="SGW60_RS13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3489..3581
                     /locus_tag="SGW60_RS13705"
     CDS             3489..3581
                     /locus_tag="SGW60_RS13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3793..4767
                     /locus_tag="SGW60_RS13710"
     CDS             3793..4767
                     /locus_tag="SGW60_RS13710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4887..5702)
                     /locus_tag="SGW60_RS13715"
     CDS             complement(4887..5702)
                     /locus_tag="SGW60_RS13715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5695..7138)
                     /locus_tag="SGW60_RS13720"
                     /pseudo=""
     CDS             complement(5695..7138)
                     /locus_tag="SGW60_RS13720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(7110..7703)
                     /locus_tag="SGW60_RS13725"
     CDS             complement(7110..7703)
                     /locus_tag="SGW60_RS13725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7967..8347)
                     /gene="blaI"
                     /locus_tag="SGW60_RS13730"
     ARG             complement(7971..8347)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8337..10094)
                     /gene="blaR1"
                     /locus_tag="SGW60_RS13735"
     ARG             complement(8341..10094)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10201..11046
                     /gene="blaZ"
                     /locus_tag="SGW60_RS13740"
     ARG             10202..11043
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11415..12023
                     /locus_tag="SGW60_RS13745"
     CDS             11415..12023
                     /locus_tag="SGW60_RS13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12437..12730
                     /locus_tag="SGW60_RS13750"
     CDS             12437..12730
                     /locus_tag="SGW60_RS13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12805..14739
                     /locus_tag="SGW60_RS13755"
     CDS             12805..14739
                     /locus_tag="SGW60_RS13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_338433578.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLTATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14743..15054
                     /locus_tag="SGW60_RS13760"
     CDS             14743..15054
                     /locus_tag="SGW60_RS13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15066..15692
                     /locus_tag="SGW60_RS13765"
     CDS             15066..15692
                     /locus_tag="SGW60_RS13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15930..16559
                     /gene="mobV"
                     /locus_tag="SGW60_RS13770"
                     /pseudo=""
     CDS             15930..16559
                     /gene="mobV"
                     /locus_tag="SGW60_RS13770"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16653..17198
                     /locus_tag="SGW60_RS13775"
     CDS             16653..17198
                     /locus_tag="SGW60_RS13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            17582..18442
                     /locus_tag="SGW60_RS13780"
     CDS             17582..18442
                     /locus_tag="SGW60_RS13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18529..18870
                     /locus_tag="SGW60_RS13785"
     CDS             18529..18870
                     /locus_tag="SGW60_RS13785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19109..19180)
                     /locus_tag="SGW60_RS13790"
     CDS             complement(19109..19180)
                     /locus_tag="SGW60_RS13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19329..19514
                     /locus_tag="SGW60_RS13795"
     CDS             19329..19514
                     /locus_tag="SGW60_RS13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19733..20476)
                     /locus_tag="SGW60_RS13800"
     CDS             complement(19733..20476)
                     /locus_tag="SGW60_RS13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843759.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRNQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10202..11046
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7437..17730
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17583..18442
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19734..20476)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15931..16205
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atactgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttatacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1621 aaaataaggg cataaaaaat aaaagccccc ccagataaag tgaggtagct ttttctttcg
     1681 acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc
     1741 aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa
     1801 gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg
     1861 tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat
     1921 tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga
     1981 accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct
     2041 aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct
     2101 ccatgtctac gcatagacac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac
     2161 ccttaactaa acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga
     2221 caagttttgg gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag
     2281 cacctatgat tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt
     2341 gtattatgat tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt
     2401 tattagtaat tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata
     2461 tttatgttgg tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt
     2521 ttgtattaaa ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt
     2581 atcttggaat taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaag
     2641 aattgaatga aaaaggattg tctaaattag ttggtacggt tgcaattgtt acgatagcaa
     2701 gttgtggcgc cgataatatt ggtttatttg ttccgtattt tgtgacatta agtgttacta
     2761 atttattact tactctgttt gtctttttaa ttttaatttt cttcttggtg tttactgcac
     2821 aaaaattagc taatatccca ggaattggag aaattgttga gaaatttagt cgttggatta
     2881 tggctatcat ttatatagct ttaggtttat ttattattat tgaaaatgac actattcaaa
     2941 caattttagg atttatattt taatttaggg tgtgatttta tatgagttat gaaaatactt
     3001 gtgatgtgat ctgtgtacat gaggataaag ttaacaatgc tttaagtttt ttagaagatg
     3061 ataaatctaa gaaattactt aacattttag aaaaaatttg tgatgagaag aaattgaaaa
     3121 tcatattatc tttgattaaa gaagatgagt tgtgtgtttg tgatatttct ttgatattga
     3181 aaatgagtgt tgcttcaact tcacatcatt taaggctttt atataaaaat gaggtacttg
     3241 atttttataa agatggaaag atggcatatt attttattaa agacgatgaa ataagagagt
     3301 ttttctctaa aaatcaggag ggtttttgaa acgagtttct tcttgtcttg atactataaa
     3361 aaacaaagtt atataacata agacgactta tcggaagtta tctatcatcg tatattcgga
     3421 gatgatataa tatacaggtc gcctatctct caggcgtcaa ttcagacgca gagaggaggt
     3481 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     3541 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     3601 gccagcatcg aaaaaatccc cacactattg cagtagtgtg gggattggtg cattaattgt
     3661 taatcatttt cgttatctag attataacac tggttagtag aggaatgcaa aaagataata
     3721 ttttaagtag tctttttgga tattatcata tgatatattt atgtaaattg attttttatt
     3781 aaaggagcat atatgagtaa tactaaaatt aaatatcaaa tttttatttc atcaacttat
     3841 ttagatttaa tagaagagcg tcaagcagta gtagaagcag ttttaaacag taataatatt
     3901 ccagcaggta tggaactttt taactcaagt agtaaaagcc aatgggaaat aataacacaa
     3961 tggatcaatg aatcagatgc agtgatatta ttgttaggtt ctagttatgg aacaattgat
     4021 agtgaagaaa atattagcta tacagaaatg gagtacaatt ttgctaaatc tttaggtaaa
     4081 cctatatatg tttttgagat gaataaagca tctaccgaat ccgcggaaaa gtctaaaaaa
     4141 ttagatgagt ttaagacaaa agttaaagaa aatagactaa ttagtccaaa tattaatgat
     4201 atttcggaat taaaaagtaa agtatctcag actttaatgc aaagtgtacc tagtgaaatt
     4261 aaagaaaata gtggatggat aagagtacag gattgtggta aaaatgtaaa aaaattaaaa
     4321 aaattggatg ctatacaaag agatttagat acatatgatt ttttgaaaga agaactttat
     4381 aaaatattca tgtatgtaaa aactttttat ttccagcaca caccatttga tgatagttat
     4441 attgaagata tagaaaacta cctgctaaat tatgaaaata atccacataa atcattcatg
     4501 aaaataaaag tttatgatta taaaaacttt ttaaaacatt taaaaaacat attgatttta
     4561 attaaacaag gaaaaaagcc attagctcaa gccggtcatt ttaaattaag cttttacgaa
     4621 gaggatttaa aattgttaca aaaaaattat aagactacgc tagtcgatat taaaggattg
     4681 aataaacatt tttataagga atgtgatagg tgcttaaaag catataatat ttttattgag
     4741 ggtataaata aacatttata tgaatgatat aagtacaccc taatcataca tatataattg
     4801 ttgtcacttt actcgatata tgagaatgac tttacctaat aaatgagaaa agcaacgcac
     4861 tatattaaaa tgcgttgctt tttctattat cgaataccta taactaaact atctctagct
     4921 gtttctacaa cttctgtact tattttatct aaaccattta tatccataat tctgtctatc
     4981 tgcgcaaata aacgatgaat cagcctaaaa ttcccttttg taattttaat aatcgtcgtt
     5041 attgcctcat aatcagtaaa gtcttcgagt tttaaatcaa atcctaagtc ttgccactta
     5101 tattctaata tatgatgcgt ctcatcttta cttagattat caaattcatg cgcaaaacct
     5161 atacgcgaat atagttgagg ataacgagat agttttttct ctatacccgg cataccaata
     5221 aatatcattg ctaaattatg ttcatcataa atagctctta attgctctaa atgttgcact
     5281 ttaaggcgat caatctcatc tactataatt aaatcaatat atttaaacat atcactataa
     5341 tgtttactat gttcatgtcc atacttattt acaacatgta atttttgacc caaatcaatg
     5401 attgcagtaa tactatataa atcattcctt aatttagttt gtttttctgc tggtgcatta
     5461 taaaatattt tatccaccga tagtatgtca tcggtcgttt tactagctaa atcttcccaa
     5521 cctctatggt taacttgttt ttcaatagta tcccaatttg tgtaatacct agacgataaa
     5581 gtttttccga caccaggttg accataacat ataccaatat actgatattt aatacaagca
     5641 tcacaaaatt cagcaaagcg tttatactct ttcgtttcaa tgaaattttg atttttagtc
     5701 attacgatat ctctttaatt ttttgacgtt tttagtcgtt tcttgaggtg aataaccaca
     5761 atttttttct tccttaatta attccgtggt acttggacta gcaatatttt gttttaagtg
     5821 ttttcttctc tgactacgag cgtgctgtat gtcttttata tctatggagt aatcagctat
     5881 ttctggacat atagcagtac aaagaaattc atctctataa aacacacgta tttcagccat
     5941 atcatttggg ttataacgaa tcagtacata ttcacctaca taagcttcta gattagtatt
     6001 actgtatcga aaaccttgaa aatgaatgcc atctgaatga acttttctag atttaggtat
     6061 ttccaacaat aataaatcaa gttgttctaa gctacttggc atattaggga aaaagtgatt
     6121 actattccaa tgactgatag gcgtggtatg aatagtacta tgttcttttt gattataatc
     6181 ttcaattaaa aagtaacgta atttttcttc aaaattgtga aaatttatta gattactagg
     6241 agtatcatta ttgtttatat atccaggcag ttgttctaag aaagtttgat taactgtctg
     6301 aaagaatcgt tctatttttc cacgaccacg aggaacacca actttcgaaa acatcaagtt
     6361 aattttcaaa tcaatagcga cttgttccat atgatgtgaa gtaaagtcac ttccatgatc
     6421 tgtgtagaat ttttcgggta taccacacac tggccaattg gtatcatttt tattccatat
     6481 tgcttggtgt agtgttaatg ctgtgttttg agcattgggg ggcatcaaaa cttaagaaat
     6541 agcctgcaat tgcacgacta tagtcatcca taataatagt tagccatggt ctattgatat
     6601 tacctttttg gtctaatata aagatatcta gcaaagtatg gtctgcttgc catatttcat
     6661 tgggtctcga ggattctcta atttgtatta aatcgtactt attttgatag tatttttcac
     6721 cctgatgaga gaaatcaata acagacttag gcatcgcttt aataacacta taaatttgtt
     6781 tataacttgg tatatcaaaa ttattttctt tacagtaatt agtgattttc ctatgaattg
     6841 tggctatact atttctttta ttcataagcg caaggcgttc aatttcatca attatctttg
     6901 gttctatttt acgtgttcct ttatcagctc ttgtcgcata gattagtcct ttaagtcctt
     6961 gttctttata tgacttattc cacctataaa gggtgcttaa cgcaatccct ttacttttag
     7021 aaatacttga taaagattgt tcgcctagga taaaaggttt tataatattg tacttttgag
     7081 tagctttttt acgtttggct tcagaaaaat tagttagata cttctccttg tttttcatct
     7141 tccttgtcct ccaatttatt gaggtaacga taaattgttg tacgtgaaac atgccactgt
     7201 tctgcaattg tcttaattgg cgtgccatta tcataaaggg tcttaagtaa gtttaaatct
     7261 ttttgattta atttttctgg tctgcctcca tatcggcctc tagcacgtgc tgcaattcgg
     7321 ccagctgaag aacgctctaa aattaaatta cgttcaaatt ctgcaaatgc tgcgaataaa
     7381 tgaaataata attgtccagt tgaacttgat ttatccattg ttatattttc ttctaaacta
     7441 tggaaactta cacctcgttc gttaagctca ttaactaatg tgattaaatc ctccatatta
     7501 cgtcccaatc tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt
     7561 gctttatcta aaccaggtct tttacttttt gaaccactca tatggtcatt aaatatcttt
     7621 tcacaaccat atgtatttaa tcgatcctcc tgtaaattta aattttgtaa tccagttgaa
     7681 actcttgcat aacctatttt caaaatacaa acctcctata tacatcttca gtgtaccata
     7741 acttaattac aaggtctttt atgaacatag attttttgtt gggtttttga acacataatc
     7801 ctatgtaatt cttacttatt tagacataaa agaagagtgt acagaaaatg gttattttct
     7861 gtacactctc atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga
     7921 gtcaagcata gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa
     7981 tatcatttaa aatatctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg
     8041 caaaattcaa cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag
     8101 cagttttcat tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg
     8161 atttgtatcg ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt
     8221 tatcactaac ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt
     8281 ttttatccca tattatattc ataacatccc attcagccat agatatttca acttgcttat
     8341 tggccattta aaacacccat tccttttaat attttttcac ttattaattc agcatttttc
     8401 ccagacgggt ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt
     8461 acgtaaccta caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc
     8521 ccatacagtt catacttttc atttttctta atcaataatg aagaagataa ttgattcttt
     8581 gcttttttac taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca
     8641 agattagata ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca
     8701 ttaccataat ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta
     8761 atacgttcga agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta
     8821 ttccaagact cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt
     8881 ataatatgac ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa
     8941 tatctttttc tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac
     9001 ataacgaaag atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg
     9061 ctttgtaagg gctttttata attataatca gttaaggatt gccccattaa aaactggctt
     9121 tgaattatca tgataaaaaa agtaaaaata caaataaaaa ttagaattaa ttttgactgc
     9181 tttttcagat cggcttcttt tatattaatt aatctatttt tgagtaatga ttttttacca
     9241 ttaaatgaat ggcttaatat atttttgttg aaaaatgagg tttttaatac ggagtccata
     9301 atagattccg cataagtttt aaattcattt ttgttaatat tattaaggac aaatctatcg
     9361 gcttctactt cattgtcatg aattatcttt ctttttacaa tatgtactaa tggattgtaa
     9421 ctcataataa tagagaagat attaaagata attaaatgta aagtatctct atttttagca
     9481 tgagcatatt catgcagtat tatatatttt agtcttttat caattacact tttaaaatat
     9541 gaactaggaa tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc
     9601 tctgcttttc gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt
     9661 ttattttttt cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat
     9721 aaggctttca aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag
     9781 atattatcaa ttgaatccca attaaactta tggatatctg ttgcgaactc ttgaacaggt
     9841 ttggtggtaa ttatgttatg gttcaagtcg tgtgacttac tttcaactgt gggcgcttga
     9901 ttattcacat tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca
     9961 gcaagcacag ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat
    10021 atgtacctaa aaaatactaa caatagaaat ataaaacaaa agcttactac actcattatt
    10081 agtaatttag ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat
    10141 attacaattg taatattatt gttttgtaaa aattacaact gtaatatcgg agggtttatt
    10201 ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg taattcaaac
    10261 agttcacatg ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt
    10321 tatgctttag atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc
    10381 tatgcttcga cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat
    10441 aagttaaata aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta
    10501 gaaaaatatg taggaaaaga catcacttta aaagaactta ttgaggcttc aatgacatat
    10561 agtgataata cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa
    10621 caacgtctaa aagaactagg agataaagta acaaatccag ttagatatga gatagaatta
    10681 aattactatt cgccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact
    10741 ttaaataaac ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat
    10801 ttaatgttta ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat
    10861 aaggttgctg ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt
    10921 gtttatccta agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat
    10981 aaaagtgata agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa
    11041 ttttaatatt ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt
    11101 ctattatcgt tgacatgtat aattttgata tcaaaacctg attttccctt tattattttc
    11161 gagatttatt ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat
    11221 aaataataga tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta
    11281 tttaaagtgc gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa
    11341 agtgacataa ttgttgaatt tatagtaact gaaacgtatg attagggtgt atattaatta
    11401 tgagatggaa atcaatgatt gttggctatg cgagagtatc atcgaacgat caaaatttag
    11461 aaagacaact tgaaaattta aagacgtttt gtgctgaaaa aatatttaca gaaaaacagt
    11521 ctgggaaatc tattgaaaat agaccagtac ttcaagaagc acttaacttt ttgaggatgg
    11581 gagatcggtt tgtagtagaa tccattgatt gtttaggtcg taattatgat gaagtgattc
    11641 ataccgttaa ttatttaaaa gacaaagaag tacaattaat gattactagc ttacctatga
    11701 tgaatgaagt ggttggcaat ccattactgg ataagtttat gaaagattta attattcaaa
    11761 tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa gcgcaaggaa
    11821 ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc cttactttat tcaccaaatg
    11881 ctaaagatcc acagaaacgt attatttatc atcgcgttgt agaaatgtta gaagaaggcc
    11941 aatcaattag taaaattgcg aaagaagtaa atataacaag gcagacgatt tacagaatta
    12001 aaaacgataa tgatttgatt taataaactt tgtttcaatg caactgagag cttctcacag
    12061 cgtctcaaaa cagatgatta taatctatta tgagttttta ataataagac aagaaaagag
    12121 agcgtaaata tgctctctct ttttctcatt aacgaatgtt tataacgcaa tcatgatgag
    12181 agtattaata cagttaatta tttgaaatac tttagtttat ataatgttga attataggta
    12241 gtgaaattgt atttattata cattgtcata tcgttgttta atgatagtta atttaaggat
    12301 aatagaatta atattatata tagatgaaca aaacaagcaa cagagcagaa aaaacacttt
    12361 tagattattt ttactcattc tctattttat ttatttttgc tataataaat aaagaatatt
    12421 aaatgtaggt gtttttatga aaaagaaatt tgtttctagt tgtattgcta gtacaatctt
    12481 attcggcact ttattaggtg taacttataa agctgaagct gcaacagtac atgtagctgg
    12541 tggtgtttgg agccatggta ttggaaaaca ttacgtatgg tcttattata gtcacaataa
    12601 aagaaatcat ggttcaacag cagtagggaa atattcatct tttagtggtg ttgctcgacc
    12661 tggtgttcaa tctaaggcat ctgctccaaa ggcttggggt ggaaacaaaa cattttatag
    12721 tcttcactaa ttacatatat taattaagga gaatagacag aattaagtaa acttaattct
    12781 gtctattctc ttgaaagagg caatatgaaa aaattcaaat tatttttaga ttttagtact
    12841 ttattattaa tttcagggct attattttta tttttcttca aagaaaatga agaaattata
    12901 cctgaaagtt ccaatatttt aacaatctct aattgggata aatctaacag taaatcaaaa
    12961 gtgttagatg tcattgaatc aggcgccaaa aatcaaaata tacaaataat taaatccgtt
    13021 aaagattttg ataataaaaa agaatttttt gttttcaact caaaacgaaa taattctgac
    13081 tttatacgta ataaaacatc acttttaact ccatcagatt tattaaacag agagataaaa
    13141 ggaaagtatt atattattgg tgaacatttc aatgtagaag agcttacgag tgaattaaaa
    13201 aaagctggtt taacatctga agttgaatac ataaatagaa acatattatt ttttgaatta
    13261 gtcatagata atgatttatt agtgcctttc atattcttag gcgtattata tcttttgtac
    13321 ttcttatatg acagaggata taatttgaaa ttttatgcta ttcaaaagct acatggcttt
    13381 tcaactacac gcattatttt tcataatatt catataaaaa tcatttattg gctagtactt
    13441 accgctattt tctttattgc taatatatta atcattcata tagccaattt agaattggat
    13501 ttcttaatgt ttattcgtag atttatcgtg ttgctttttg tttttgcttg tattactaca
    13561 ttgctgtggc tgatttcgta tagtcttctt ttgaagttaa gtattccatt aatcttaaaa
    13621 gggaaaaaag gatataagtt ttcaatattt atgggtacct tcaccaaatg tatcatggtg
    13681 ctaatactat cttttttact ggcacaaaat ttaaatgctt atacgaagtt aaagaatata
    13741 tatgactctg aaaaaatctg gcaaaagtta gataattact atacattaga gatttctcct
    13801 aatattagaa attcagaaga aaaacaaatt ttagaaacta atatatacaa tttaattaag
    13861 aaaagcgaac aacttggtgg attgctttta aagaataata atatagccaa tcccgataaa
    13921 aacaattaca ttcctgaaaa tggcaatgtc ttttttatca ataacaattt tctgaatttc
    13981 tataaaaata taaatcatga ttttaaaatg attgacaatc attcggataa aataaacgtg
    14041 tttattcctc caaggttaca atatcaaaaa tctgaaattc aaaaaaatca ccaaggatgg
    14101 attgactttc aaaagcaaca aaacaaaaaa gtagatgtgc aagtactgtc aaaaaacgta
    14161 tctgtttttt cttttgatcg cacaactaat ttgaaatttg ggtatctaga ttctccaata
    14221 gtaatgttgt tgacacttga cgatttaaca ggagattttt atttagctgc tgtttctcaa
    14281 ggtggatatc tatttaaaga tttagataca cttaaacagt tgcttaaaga taatcaccta
    14341 gaagaagaaa ttagcggtat aactaattac aaggattctg tgttaaatga attaaatgaa
    14401 acgaaaacaa aaatgataat aacaatagtt actattatta ttaacgtttt cattcttttg
    14461 acagctactg tatttgaaac aattcaatat tttagctgga ataaaaagca actattatta
    14521 agaaaaattc atggttattc attattcagc agtaatgtac gttatttaac aatttctatc
    14581 ttactttcta ttatgttagc ttacactacg catattttat ttggttcaaa gatattacta
    14641 ttcataataa tgtctattgc tattattcaa catttacttc aaattgctta tattaaatat
    14701 cttgaaaaat actttaaaga tttaatgagg gagatttaaa caatgaaaag aactttaatt
    14761 attgtaacaa ttgtactatt aatcatcata cttagtctgt tattggttag aaatgagcat
    14821 ttagatcgtt ttaacccact gttaaaagaa aaagtatctt atgccaaagt tccaaaagat
    14881 acccaggact atagaaatat aactgtatac tctaaaaatg gagaaaaaaa gagttataaa
    14941 ttggattttt taggttatga tcctacaaaa gaatatgtga aagtaaatca taaagggaaa
    15001 tatgtgcgtt cgatagaata cattacaaaa gatattccta gctttttaaa atgaggtgac
    15061 cgatagtgat aaaacttgaa aatgtttttg taaaaaaagg taataaaaac attttagacg
    15121 gatgtaactt taattttgaa aaaggaaaat catatgcttt agttggagaa agtggcgctg
    15181 gaaaatctac tttacttaac ataatcgctg ggttcgaaga tgtatcacaa ggaagcatat
    15241 atattgaaga taagttacta aaaaagaaag tcgattttta tagatatacg ttagggtatt
    15301 tgtttcaaaa ttttgcttta cttgaaaatc aaacaatcag tcaaaattta gatttagccc
    15361 taaagttcaa aaagaataaa aaagataata tgaacttaaa gaaagaagta ttaaaaaagg
    15421 tcggcctaga tttagatatc aagagaattg ttagttctct aagcggtggt gaacaacaaa
    15481 gagtagcatt ggcaagatta atattaaaag atccgaaaat cattttagct gatgaaccta
    15541 ctgggtcact agatacgaaa aatggaaaaa tagttattga tttattattg aagctacttg
    15601 atgaaaataa aactatgatt gtcgtaacgc atgatttaga gcttgcgaaa cgatttgatg
    15661 tcatagtcaa tatttctgag cttagaagtt aagaaatatt gataggtata gccatacata
    15721 gagaaaaaac aatatgaaat atgattagtc attacttttg agttttttaa tttaaggact
    15781 ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca cacgttttta
    15841 atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt ttaggtgtta
    15901 taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga gttgttaaag
    15961 tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa aataaaaatt
    16021 atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta gtcaatgata
    16081 ctaagtttga ttttaataaa aaaattgatg agaaaatcga aaaaaattat aaagggaaac
    16141 gcaaaattag aacagatgcc attaaacata ttgatggatt aattacatca gataatgtgt
    16201 tttttaatca attatctgaa gaagagacaa aatagttttt taagcatgct aaagcgttct
    16261 tggaagaaga atacggtaaa gaaaatcttt tatatgcgac agtacatatg gatgagataa
    16321 caccacatat gcattatggc gtagttccta ttactaaaga tggacgttta agtgcgaaag
    16381 aagttgtagg taataaaaaa gcattaaccg aattccaaga tagattcaat acgtatatta
    16441 ataagcaagg ctatgattta aaacgaggaa tttctagaca acttacaaaa gaaaaacatg
    16501 atcaagttag ccgttataaa caaaaaacag aatatcataa acaaatgcat atgcgctaga
    16561 agcaaataga ggattattta aagcaagaaa atgataaatt gatacaaaac taccaaaaat
    16621 cattagatac gcttaaaaag cttctgagtg tcatgtatga aattaaaact aaaaatgtag
    16681 gtggatggtt tcataaagag aagcaagaaa caggcaatat tgtaattact aaaactgatt
    16741 ttgaaaaata cactaaacaa attaaagcag cacagatgat attagatgat tatgaatgta
    16801 ttaaaagtgg gaagtcatta aaaaaagcag agaaacaaaa tgaaagttta gttaatgaat
    16861 tgactagtgt ccatatggaa aatgaaaagc tggttgaaga atttaatgat ttagcacaac
    16921 gttataatta tttgttgtca gagaatgaaa agaaagataa agaactaaat tatacgctta
    16981 agttattcaa tcaagttttt aaaatcatta aaagtatgat gaaagaagag cgttatcata
    17041 cactaataaa tcatattgat aatcatttag acaattctaa aatacgtgaa gtaatgacga
    17101 tagataacaa tgatgaacag ttctttaaga agaaatatca agcacaagaa cgagaaatca
    17161 tttttaaaga agatagagaa gatggttata cattataaaa atagatattt aaatgcattt
    17221 gtttgaggtt aattattttt taggatgaaa aataggtagc ccccctcgaa ctttttaata
    17281 tatttttata aatcttttta aaaacctttt taggggcttg ttcagcccta gagcaacaag
    17341 ggatttcaat gcctaaagga gtgtttttgc cacataaaag gagtgttttt gccacataaa
    17401 aggagtgttt ttgccacata aaaggagtgt ttttgccaca taaaaggagt gttttaaaaa
    17461 gttgtactcc ttttatggtt tgacattgat aataaagtag tttattgtga ataaaagttt
    17521 tcaaatggga gtgtatattc aaacgatact cctttaggtt cgtaataaag ggggctgtat
    17581 catgacagga gagacagttg tatataaaaa tgaaatgaat ttagttccat taaggcgatt
    17641 tacagctact gaaattaatt tattttttgc gatgtgtaat aaattaaaag agcaagatac
    17701 taatacatta cgtttgtctt ttgatgaatt aaaaaaatta agtaattata gtccagaaac
    17761 acgtaatatt aatagatttg ctaatgattt agataatgtg tataaaaaga tgttgaattt
    17821 aaccattaga tatgaagatg atgatgtaat agaaagattc gttttattca atcattatag
    17881 aatccataag cgagaacaat atctagaaat atcaacttct tcaaatttaa aacacatatt
    17941 gaattcaatt actaataatt ttacaaaatt tgaattaaaa gaaatgacta ggcttaaatc
    18001 tacatattct aaaaatatgt ttagattact taaacaatac aaacatacag gctatttaaa
    18061 aattcacatc gatgatttta aaaatcgttt agatatacct aaatcttatc gtatgactga
    18121 tattaacaaa aatgttttta aacctattat tattgaatta ggttctatat ttaataatct
    18181 tactatcaat aaaatcaaag cgaaaaaagg gcgtaaaatt gaatggatag agttcacatt
    18241 tgacgctgag aaacgcattc ataacaaacg acaacctcaa atgtccaaga tagataaatc
    18301 aagacaatat gtgaggcgtg aaaagacgcc taaatggtta gaagaacggt catatgaaaa
    18361 gcaacctcaa aaagattacg acccacaatt agagaaagaa cgagaggatt ttttaaaaca
    18421 acttgaactg aattgggaat aacgcaactt ttcgttgcga gttggttaac taaaagtatc
    18481 gtgacttttc aattatttta attatagttt gagttaagga gtgattttat gaaattagct
    18541 gaagctataa aagaacagag agaattaaaa ggatggtctc aagaggaatt agccaatata
    18601 ttaaaggttt ccagacaaag tgtttctaaa tgggaaagtg ccaaaaacta tccttcctta
    18661 gatattttga ttgctatgag cgatttattc ggaatctctt tagagcattt aattaaagga
    18721 gatgcacgtt ttaaaaaagt tattttagag ggaaattata gagagagtaa cagggtacct
    18781 tccatagttg attttcttta tgatttttgg tggcttttct ttcctgttgc cggattttta
    18841 gtttgggcca ttcattcgtt catgggttga ttttaaaatc aaaatttaat gcacatcagg
    18901 caatatgaaa aaggaaagta tttttacgac accttgaaat gtattgataa gaatagaaga
    18961 gtttacaaaa ggcaatatga aatatatact aaaagtaaca agaatttcgt ttgtaaacgc
    19021 acaaaacccc gaactattcg ccgtagttcg gggttttttg gtgaattggc tttaatcgtc
    19081 tatattattt tttatcacgt ttatggagct aataaccaaa taacgtaacg agacaaccac
    19141 tgattgccgt tgtcatgatg tgaacaagaa tttcattcat aaatcgcacc tcctctctac
    19201 gccgaattga catctgagag atagacgacc ttcacattat aacaaatctc tccttccatg
    19261 aaataacatg aatattaata aatgttgtta tatattaaag ataaataaat ataagggtgg
    19321 gattgataat gtttggcgat caaagacaag aagctacaaa atatgtcatt aaagaaggtt
    19381 atcaagatat ttatttcctc aacaaaaacg gggaatggta ttatttcgaa gtaagaagtg
    19441 tctggcgtgg caaacatatt attagagtta aagatggttt gttaggttgg agaaaagaaa
    19501 tagtaactga ataaagatac aaaatacttg ccaatgcaaa agaatgaaaa cgcgtcaaat
    19561 caacgatgta taaaagatgc ataaaagata atgaaagtaa aaagccataa atgccgtcat
    19621 ataggcattt atggcttttt gtttggttaa cataatcgat gattatcaga agttcaattc
    19681 acataaaaaa gcacggctaa tttatgaact tgtcgtacct ttttaattaa aattagttac
    19741 caaatagacg actccaaaac ccctttttag gttccgtttc ttcactcttt tcttctatat
    19801 cactatcatt gtcatttgga ttagctgaaa cgtcttctct ttgtgcttct tcaccttgtg
    19861 tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt tctttagttt
    19921 cttcctgatt tcggttaata tttacaggac tagtagtata tgttttttct tgtgcatcaa
    19981 cgttttgtct agcgttagta gatgtatcaa agggataatt aaggtgtttt tctttttcta
    20041 attgattttc taatttttga atctttttat tactctctaa tgccagaact tgctgattct
    20101 caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt gtttcatgac
    20161 gactttcttg tttttcaatt tgattattta aagtattaat ctgattttta agtatttcta
    20221 ctatttgagc atcgctttta gattcaaaat taatattatc cgactctttt ttttgtttgt
    20281 cttcagtagc actttcaaaa ccatatttct ttttattttc atttactctt tgaatgattt
    20341 tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt gtctctatat
    20401 tcaatctctt aatattatta aaaatcgttt gcttactaac ccctaattct tcactcaacc
    20461 tttttacact tttcatatca tcaacccttt ataaaatgtt tataaaccct tagtaaaata
    20521 ttataagctt ataacgatta ataataaagt aatcgacaaa taaaaatata aattcgccaa
    20581 cctttttatc aagggtttgt aaagggttta tggtgtttat caaaggttta taaacctata
    20641 ttttcccttt tttaagttta ttcaaagtgc tataataacc ttaatataac aaaaacccca
    20701 actactggta atagtcgggg t
//
