LOCUS       NZ_CP138665            20446 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus aureus strain DA70504 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP138665
VERSION     NZ_CP138665.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN38170760
            Assembly: GCF_036670075.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20446)
  AUTHORS   Heidarian,S., Guliaev,A., Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     High prevalence of heteroresistance in Staphylococcus aureus is
            caused by a multitude of mutations in core genes
  JOURNAL   PLoS Biol 22 (1), e3002457 (2024)
   PUBMED   38175839
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20446)
  AUTHORS   Heidarian,S., Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2023) Medical Biochemistry and Microbiology,
            Uppsala University, Husargatan 3, Uppsala 75123, Sweden
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler or Flye + medaka + Polypolish, SPAdes
            v. v0.4.8, v2.9.1, v1.6.0, v0.5.0, 3.15.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 545.080821428571x
            Sequencing Technology             :: DNBseq and Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_036670075.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 15:33:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,715
            CDSs (total)                      :: 2,635
            Genes (coding)                    :: 2,557
            CDSs (with protein)               :: 2,557
            Genes (RNA)                       :: 80
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 50 of 78
            Pseudo Genes (incomplete)         :: 26 of 78
            Pseudo Genes (internal stop)      :: 11 of 78
            Pseudo Genes (multiple problems)  :: 8 of 78
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP138665.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20446
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="DA70504"
                     /isolation_source="superficial wound"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="Sweden: Stockholm"
     gene            166..842
                     /locus_tag="SGW61_RS13460"
                     /pseudo=""
     CDS             166..842
                     /locus_tag="SGW61_RS13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <853..1135
                     /locus_tag="SGW61_RS13465"
                     /pseudo=""
     CDS             <853..1135
                     /locus_tag="SGW61_RS13465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2346..2963
                     /gene="cadD"
                     /locus_tag="SGW61_RS13470"
     ARG             2347..2960
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2982..3329
                     /locus_tag="SGW61_RS13475"
     CDS             2982..3329
                     /locus_tag="SGW61_RS13475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3498..3590
                     /locus_tag="SGW61_RS13480"
     CDS             3498..3590
                     /locus_tag="SGW61_RS13480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3802..4776
                     /locus_tag="SGW61_RS13485"
     CDS             3802..4776
                     /locus_tag="SGW61_RS13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4896..5711)
                     /locus_tag="SGW61_RS13490"
     CDS             complement(4896..5711)
                     /locus_tag="SGW61_RS13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5704..7147)
                     /locus_tag="SGW61_RS13495"
                     /pseudo=""
     CDS             complement(5704..7147)
                     /locus_tag="SGW61_RS13495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(7119..7712)
                     /locus_tag="SGW61_RS13500"
     CDS             complement(7119..7712)
                     /locus_tag="SGW61_RS13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7976..8356)
                     /gene="blaI"
                     /locus_tag="SGW61_RS13505"
     ARG             complement(7980..8356)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8346..10103)
                     /gene="blaR1"
                     /locus_tag="SGW61_RS13510"
     ARG             complement(8350..10103)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10210..11055
                     /gene="blaZ"
                     /locus_tag="SGW61_RS13515"
     ARG             10211..11052
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11424..12032
                     /locus_tag="SGW61_RS13520"
     CDS             11424..12032
                     /locus_tag="SGW61_RS13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12446..12739
                     /locus_tag="SGW61_RS13525"
     CDS             12446..12739
                     /locus_tag="SGW61_RS13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12814..14748
                     /locus_tag="SGW61_RS13530"
     CDS             12814..14748
                     /locus_tag="SGW61_RS13530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14752..15063
                     /locus_tag="SGW61_RS13535"
     CDS             14752..15063
                     /locus_tag="SGW61_RS13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15075..15701
                     /locus_tag="SGW61_RS13540"
     CDS             15075..15701
                     /locus_tag="SGW61_RS13540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15799..16284
                     /gene="mobV"
                     /locus_tag="SGW61_RS13545"
                     /pseudo=""
     CDS             15799..16284
                     /gene="mobV"
                     /locus_tag="SGW61_RS13545"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16378..16923
                     /locus_tag="SGW61_RS13550"
     CDS             16378..16923
                     /locus_tag="SGW61_RS13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            17307..18167
                     /locus_tag="SGW61_RS13555"
     CDS             17307..18167
                     /locus_tag="SGW61_RS13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18254..18595
                     /locus_tag="SGW61_RS13560"
     CDS             18254..18595
                     /locus_tag="SGW61_RS13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18834..18905)
                     /locus_tag="SGW61_RS13565"
     CDS             complement(18834..18905)
                     /locus_tag="SGW61_RS13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19054..19239
                     /locus_tag="SGW61_RS13570"
     CDS             19054..19239
                     /locus_tag="SGW61_RS13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19458..20201)
                     /locus_tag="SGW61_RS13575"
     CDS             complement(19458..20201)
                     /locus_tag="SGW61_RS13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10211..11055
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7446..17739
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17308..18167
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19459..20201)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.731"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atactgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttagacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1621 aaaataaggg cataaaaaat aaaagccccc ccagataaag tgaggtagct ttttctttcg
     1681 acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta taaatctaca tcactttttc
     1741 aagaatgtag tagcaatatt caacgcaaat taatttttat aactgctcgg aatatctcaa
     1801 gccgtttctt taattttgaa ataaaaaaat cgacgaaggt cgattacgtt tttgcacatg
     1861 tcgatttatc cgacgtataa gtgcgccctt acgggattta actagattat aacgacgaat
     1921 tttagacctg taaagcaata acaattaggt ctaccaggta gataaagtgt acaaagtaga
     1981 accgaaaaag ttatttattt tgaagatttt tcgtagatat aatttgctaa taaacttcct
     2041 aaaactgaat aaagaaaaat agttaaactc atgtaatcac tccataattc tgaagtgtct
     2101 ccatgtctac gcatagacac gcatttatgc cgagaaaatt tattgtgcgt tgagaagaac
     2161 ccttaactaa acttgcagac gaatgtcggc atagcgtgag ctattaagcc gaccattcga
     2221 caagttttgg gattgttaag ggttccgagg ctcaacgtca ataaagcaat tggaataaag
     2281 cacctatgat tatttaaaaa tataagttat aatacattca aaaatatttt tgaatgaggt
     2341 gtattatgat tcaaacggtt gttgctgctg ctgttcttta tattgctaca gcagttgatt
     2401 tattagtaat tttattaata ttttttgcta gagcaaagac tagaaaagaa tatagaaata
     2461 tttatgttgg tcaatattta gggtctatta ttttaatatt agttagtttg tttttagctt
     2521 ttgtattaaa ttatgttcca gaaaagtgga tattaggttt attgggttta ataccaattt
     2581 atcttggaat taaagtggct atttatgatg attgtgaagg agaaaagaga gctaaaaaag
     2641 aattgaatga aaaaggattg tctaaattag ttggtacggt tgcaattgtt acgatagcaa
     2701 gttgtggcgc cgataatatt ggtttatttg ttccgtattt tgtgacatta agtgttacta
     2761 atttattact tactctgttt gtctttttaa ttttaatttt cttcttggtg tttactgcac
     2821 aaaaattagc taatatccca ggaattggag aaattgttga gaaatttagt cgttggatta
     2881 tggctatcat ttatatagct ttaggtttat ttattattat tgaaaatgac actattcaaa
     2941 caattttagg atttatattt taatttaggg tgtgatttta tatgagttat gaaaatactt
     3001 gtgatgtgat ctgtgtacat gaggataaag ttaacaatgc tttaagtttt ttagaagatg
     3061 ataaatctaa gaaattactt aacattttag aaaaaatttg tgatgagaag aaattgaaaa
     3121 tcatattatc tttgattaaa gaagatgagt tgtgtgtttg tgatatttct ttgatattga
     3181 aaatgagtgt tgcttcaact tcacatcatt taaggctttt atataaaaat gaggtacttg
     3241 atttttataa agatggaaag atggcatatt attttattaa agacgatgaa ataagagagt
     3301 ttttctctaa aaatcaggag ggtttttgaa acgagtgaaa cgagtttctt cttgtcttga
     3361 tactataaaa aacaaagtta tataacataa gacgacttat cggaagttat ctatcatcgt
     3421 atattcggag atgatataat atacaggtcg cctatctctc aggcgtcaat tcagacgcag
     3481 agaggaggtg cattactttg ctaatcattt tcgttcacat catagcacca gtcatcagtg
     3541 gctgtgctgt tgcgtattat acttattggc ttagtaaacg caacaaataa ttaataggcg
     3601 actttataag ccagcatcga aaaaatcccc acactattgc agtagtgtgg ggattggtgc
     3661 attaattgtt aatcattttc gttatctaga ttataacact ggttagtaga ggaatgcaaa
     3721 aagataatat tttaagtagt ctttttggat attatcatat gatatattta tgtaaattga
     3781 ttttttatta aaggagcata tatgagtaat actaaaatta aatatcaaat ttttatttca
     3841 tcaacttatt tagatttaat agaagagcgt caagcagtag tagaagcagt tttaaacagt
     3901 aataatattc cagcaggtat ggaacttttt aactcaagta gtaaaagcca atgggaaata
     3961 ataacacaat ggatcaatga atcagatgca gtgatattat tgttaggttc tagttatgga
     4021 acaattgata gtgaagaaaa tattagctat acagaaatgg agtacaattt tgctaaatct
     4081 ttaggtaaac ctatatatgt ttttgagatg aataaagcat ctaccgaatc cgcggaaaag
     4141 tctaaaaaat tagatgagtt taagacaaaa gttaaagaaa atagactaat tagtccaaat
     4201 attaatgata tttcggaatt aaaaagtaaa gtatctcaga ctttaatgca aagtgtacct
     4261 agtgaaatta aagaaaatag tggatggata agagtacagg attgtggtaa aaatgtaaaa
     4321 aaattaaaaa aattggatgc tatacaaaga gatttagata catatgattt tttgaaagaa
     4381 gaactttata aaatattcat gtatgtaaaa actttttatt tccagcacac accatttgat
     4441 gatagttata ttgaagatat agaaaactac ctgctaaatt atgaaaataa tccacataaa
     4501 tcattcatga aaataaaagt ttatgattat aaaaactttt taaaacattt aaaaaacata
     4561 ttgattttaa ttaaacaagg aaaaaagcca ttagctcaag ccggtcattt taaattaagc
     4621 ttttacgaag aggatttaaa attgttacaa aaaaattata agactacgct agtcgatatt
     4681 aaaggattga ataaacattt ttataaggaa tgtgataggt gcttaaaagc atataatatt
     4741 tttattgagg gtataaataa acatttatat gaatgatata agtacaccct aatcatacat
     4801 atataattgt tgtcacttta ctcgatatat gagaatgact ttacctaata aatgagaaaa
     4861 gcaacgcact atattaaaat gcgttgcttt ttctattatc gaatacctat aactaaacta
     4921 tctctagctg tttctacaac ttctgtactt attttatcta aaccatttat atccataatt
     4981 ctgtctatct gcgcaaataa acgatgaatc agcctaaaat tcccttttgt aattttaata
     5041 atcgtcgtta ttgcctcata atcagtaaag tcttcgagtt ttaaatcaaa tcctaagtct
     5101 tgccacttat attctaatat atgatgcgtc tcatctttac ttagattatc aaattcatgc
     5161 gcaaaaccta tacgcgaata tagttgagga taacgagata gttttttctc tatacccggc
     5221 ataccaataa atatcattgc taaattatgt tcatcataaa tagctcttaa ttgctctaaa
     5281 tgttgcactt taaggcgatc aatctcatct actataatta aatcaatata tttaaacata
     5341 tcactataat gtttactatg ttcatgtcca tacttattta caacatgtaa tttttgaccc
     5401 aaatcaatga ttgcagtaat actatataaa tcattcctta atttagtttg tttttctgct
     5461 ggtgcattat aaaatatttt atccaccgat agtatgtcat cggtcgtttt actagctaaa
     5521 tcttcccaac ctctatggtt aacttgtttt tcaatagtat cccaatttgt gtaataccta
     5581 gacgataaag tttttccgac accaggttga ccataacata taccaatata ctgatattta
     5641 atacaagcat cacaaaattc agcaaagcgt ttatactctt tcgtttcaat gaaattttga
     5701 tttttagtca ttacgatatc tctttaattt tttgacgttt ttagtcgttt cttgaggtga
     5761 ataaccacaa tttttttctt ccttaattaa ttccgtggta cttggactag caatattttg
     5821 ttttaagtgt tttcttctct gactacgagc gtgctgtatg tcttttatat ctatggagta
     5881 atcagctatt tctggacata tagcagtaca aagaaattca tctctataaa acacacgtat
     5941 ttcagccata tcatttgggt tataacgaat cagtacatat tcacctacat aagcttctag
     6001 attagtatta ctgtatcgaa aaccttgaaa atgaatgcca tctgaatgaa cttttctaga
     6061 tttaggtatt tccaacaata ataaatcaag ttgttctaag ctacttggca tattagggaa
     6121 aaagtgatta ctattccaat gactgatagg cgtggtatga atagtactat gttctttttg
     6181 attataatct tcaattaaaa agtaacgtaa tttttcttca aaattgtgaa aatttattag
     6241 attactagga gtatcattat tgtttatata tccaggcagt tgttctaaga aagtttgatt
     6301 aactgtctga aagaatcgtt ctatttttcc acgaccacga ggaacaccaa ctttcgaaaa
     6361 catcaagtta attttcaaat caatagcgac ttgttccata tgatgtgaag taaagtcact
     6421 tccatgatct gtgtagaatt tttcgggtat accacacact ggccaattgg tatcattttt
     6481 attccatatt gcttggtgta gtgttaatgc tgtgttttga gcattggggg gcatcaaaac
     6541 ttaagaaata gcctgcaatt gcacgactat agtcatccat aataatagtt agccatggtc
     6601 tattgatatt acctttttgg tctaatataa agatatctag caaagtatgg tctgcttgcc
     6661 atatttcatt gggtctcgag gattctctaa tttgtattaa atcgtactta ttttgatagt
     6721 atttttcacc ctgatgagag aaatcaataa cagacttagg catcgcttta ataacactat
     6781 aaatttgttt ataacttggt atatcaaaat tattttcttt acagtaatta gtgattttcc
     6841 tatgaattgt ggctatacta tttcttttat tcataagcgc aaggcgttca atttcatcaa
     6901 ttatctttgg ttctatttta cgtgttcctt tatcagctct tgtcgcatag attagtcctt
     6961 taagtccttg ttctttatat gacttattcc acctataaag ggtgcttaac gcaatccctt
     7021 tacttttaga aatacttgat aaagattgtt cgcctaggat aaaaggtttt ataatattgt
     7081 acttttgagt agctttttta cgtttggctt cagaaaaatt agttagatac ttctccttgt
     7141 ttttcatctt ccttgtcctc caatttattg aggtaacgat aaattgttgt acgtgaaaca
     7201 tgccactgtt ctgcaattgt cttaattggc gtgccattat cataaagggt cttaagtaag
     7261 tttaaatctt tttgatttaa tttttctggt ctgcctccat atcggcctct agcacgtgct
     7321 gcaattcggc cagctgaaga acgctctaaa attaaattac gttcaaattc tgcaaatgct
     7381 gcgaataaat gaaataataa ttgtccagtt gaacttgatt tatccattgt tatattttct
     7441 tctaaactat ggaaacttac acctcgttcg ttaagctcat taactaatgt gattaaatcc
     7501 tccatattac gtcccaatct atctaatctc caaacaacaa tcgtatctcc tgacctcgca
     7561 aattcaattg ctttatctaa accaggtctt ttactttttg aaccactcat atggtcatta
     7621 aatatctttt cacaaccata tgtatttaat cgatcctcct gtaaatttaa attttgtaat
     7681 ccagttgaaa ctcttgcata acctattttc aaaatacaaa cctcctatat acatcttcag
     7741 tgtaccataa cttaattaca aggtctttta tgaacataga ttttttgttg ggtttttgaa
     7801 cacataatcc tatgtaattc ttacttattt agacataaaa gaagagtgta cagaaaatgg
     7861 ttattttctg tacactctca tctttaataa tatattttaa atgtcattaa caaaactaat
     7921 ttaataagag tcaagcatag tttacatatg tattatgttt gaaacatacc tctaattact
     7981 ttttactaat atcatttaaa atatctcgca attcttcaat ttctttgtta tttaattctt
     8041 catttttcgc aaaattcaac actaaacttt tcatatcccc tccatacagt ttattaagaa
     8101 aggttttagc agttttcatt ttaatatcgt cttctttaat atttgatgag taaaaataaa
     8161 tattttctga tttgtatcgt tttataatct cttttttata tagtcttgtg attaatgttc
     8221 taatcgtttt atcactaact tctttatatt tttgaatttc aactacaatt tcattagctg
     8281 atactgattt tttatcccat attatattca taacatccca ttcagccata gatatttcaa
     8341 cttgcttatt ggccatttaa aacacccatt ccttttaata ttttttcact tattaattca
     8401 gcatttttcc cagacgggtt tccatctgat aaatgtgtag caaaataata cttatcatga
     8461 tttgtaatta cgtaacctac aaaccaccca ttattatact tcccgtttac tatacctgta
     8521 cctgttttcc catacagttc atacttttca tttttcttaa tcaataatga agaagataat
     8581 tgattctttg cttttttact aaaatggtta ttttgttcca tcatattttt aaaaactatt
     8641 acttgttcaa gattagatat tttcaaacta tcttccatcc aatagctttt ataacttccc
     8701 aaattttcat taccataatt taattgcttg agttgagccg cagtatagtt ctttggtatt
     8761 tgattactaa tacgttcgaa gtaccaatta actgaatttt gcattgctgt atttaaatct
     8821 tgttccttat tccaagactc gaaaagataa tgtttatgat tccatgacat acgtgaattt
     8881 ttatcactta taatatgacg gtcaagtcca aacagtgcta aataaatttt gtaagttgaa
     8941 tcaggagaat atctttttct actttctttt tcattataaa tatagtattt gtctttcttc
     9001 atgctgtaca taacgaaaga tccactattt gaaccaaaat ttttactttc atctaaaatt
     9061 tggtaatcgc tttgtaaggg ctttttataa ttataatcag ttaaggattg ccccattaaa
     9121 aactggcttt gaattatcat gataaaaaaa gtaaaaatac aaataaaaat tagaattaat
     9181 tttgactgct ttttcagatc ggcttctttt atattaatta atctattttt gagtaatgat
     9241 tttttaccat taaatgaatg gcttaatata tttttgttga aaaatgaggt ttttaatacg
     9301 gagtccataa tagattccgc ataagtttta aattcatttt tgttaatatt attaaggaca
     9361 aatctatcgg cttctacttc attgtcatga attatctttc tttttacaat atgtactaat
     9421 ggattgtaac tcataataat agagaagata ttaaagataa ttaaatgtaa agtatctcta
     9481 tttttagcat gagcatattc atgcagtatt atatatttta gtcttttatc aattacactt
     9541 ttaaaatatg aactaggaat caaaataata tatttcccat accaaaaagt tattggagat
     9601 tgaatagcct ctgcttttcg aatcacaata ttttttttat attgatggtt gaaaagtatc
     9661 gtatctattt tatttttttc attttcgttt agataaagtg actgtttctt taaatattta
     9721 agatataata aggctttcaa aaatttaaaa cttaaaataa taactaaaac tatccaaata
     9781 actgtgcaga tattatcaat tgaatcccaa ttaaacttat ggatatctgt tgcgaactct
     9841 tgaacaggtt tggtggtaat tatgttatgg ttcaagtcgt gtgacttact ttcaactgtg
     9901 ggcgcttgat tattcacatt attaaatttt ataaaagaga atttaattgg gataaaagga
     9961 attaatccag caagcacagt tagataccaa actttataat ttaaactata attaaaatag
    10021 cgttttaata tgtacctaaa aaatactaac aatagaaata taaaacaaaa gcttactaca
    10081 ctcattatta gtaatttagc cattttgaca ccttctttca aatatttata ataaacaatt
    10141 gacatcaata ttacaattgt aatattattg ttttgtaaaa attacaactg taatatcgga
    10201 gggtttattt tgaaaaagtt aatattttta attgtaatgg ctttagtttt aagtgcatgt
    10261 aattcaaaca gttcacatgc caaagagtta aatgatttag aaaaaaaata taatgctcat
    10321 attggtgttt atgctttaga tactaaaagt ggtaaggaag taaaatttaa ttcagataag
    10381 agatttgcct atgcttcgac ttcaaaagcg ataaatagtg ctattttgtt agaacaagta
    10441 ccttataata agttaaataa aaaagtacat attaacaaag atgatatagt tgcttattct
    10501 cctattttag aaaaatatgt aggaaaagac atcactttaa aagaacttat tgaggcttca
    10561 atgacatata gtgataatac agcaaacaat aaaattataa aagaaatcgg tggaatcaaa
    10621 aaagttaaac aacgtctaaa agaactagga gataaagtaa caaatccagt tagatatgag
    10681 atagaattaa attactattc gccaaagagc aaaaaagata cttcaacgcc tgctgctttc
    10741 ggcaagactt taaataaact tatcgcaaat ggaaaattaa gcaaaaaaaa taaaaatttc
    10801 ttacttgatt taatgtttaa taataaaaac ggagacactt taattaaaga tggtgttcca
    10861 aaagactata aggttgctga taaaagtggt caagcaataa catatgcttc tagaaatgat
    10921 gttgcttttg tttatcctaa gggccaatct gaacctattg ttttagtcat ttttacgaat
    10981 aaagacaata aaagtgataa gccaaatgat aagttgataa gtgaaaccgc caagagtgta
    11041 atgaaggaat tttaatattc taaatgcata ataaatactg ataacatctt atagtttgta
    11101 ttatattttc tattatcgtt gacatgtata attttgatat caaaacctga ttttcccttt
    11161 attattttcg agatttattt tcttaattct ctttaacaaa ctagaaatat tgtatataca
    11221 aaaaatcata aataatagat gaatagttta attataggtg ttcatcaatc gaaaaagcaa
    11281 cgtatcttat ttaaagtgcg ttgctttttt ctcatttata aggttaaata attctcatat
    11341 atcaagcaaa gtgacataat tgttgaattt atagtaactg aaacgtatga ttagggtgta
    11401 tattaattat gagatggaaa tcaatgattg ttggctatgc gagagtatca tcgaacgatc
    11461 aaaatttaga aagacaactt gaaaatttaa agacgttttg tgctgaaaaa atatttacag
    11521 aaaaacagtc tgggaaatct attgaaaata gaccagtact tcaagaagca cttaactttt
    11581 tgaggatggg agatcggttt gtagtagaat ccattgattg tttaggtcgt aattatgatg
    11641 aagtgattca taccgttaat tatttaaaag acaaagaagt acaattaatg attactagct
    11701 tacctatgat gaatgaagtg gttggcaatc cattactgga taagtttatg aaagatttaa
    11761 ttattcaaat attagcaatg gtttcagaac aagagagaaa tgaaagtaaa cgtcgacaag
    11821 cgcaaggaat tcaagttgcg aaggaaaaag gcgtatataa agggcgcccc ttactttatt
    11881 caccaaatgc taaagatcca cagaaacgta ttatttatca tcgcgttgta gaaatgttag
    11941 aagaaggcca atcaattagt aaaattgcga aagaagtaaa tataacaagg cagacgattt
    12001 acagaattaa aaacgataat gatttgattt aataaacttt gtttcaatgc aactgagagc
    12061 ttctcacagc gtctcaaaac agatgattat aatctattat gagtttttaa taataagaca
    12121 agaaaagaga gcgtaaatat gctctctctt tttctcatta acgaatgttt ataacgcaat
    12181 catgatgaga gtattaatac agttaattat ttgaaatact ttagtttata taatgttgaa
    12241 ttataggtag tgaaattgta tttattatac attgtcatat cgttgtttaa tgatagttaa
    12301 tttaaggata atagaattaa tattatatat agatgaacaa aacaagcaac agagcagaaa
    12361 aaacactttt agattatttt tactcattct ctattttatt tatttttgct ataataaata
    12421 aagaatatta aatggaggtg tttttatgaa aaagaaattt gtttctagtt gtattgctag
    12481 tacaatctta ttcggcactt tattaggtgt aacttataaa gctgaagctg caacagtaca
    12541 tgtagctggt ggtgtttgga gccatggtat tggaaaacat tacgtatggt cttattatag
    12601 tcacaataaa agaaatcatg gttcaacagc agtagggaaa tattcatctt ttagtggtgt
    12661 tgctcgacct ggtgttcaat ctaaggcatc tgctccaaag gcttggggtg gaaacaaaac
    12721 attttatagt cttcactaat tacatatatt aattaaggag aatagacaga attaagtaaa
    12781 cttaattctg tctattctct tgaaagaggc aatatgaaaa aattcaaatt atttttagat
    12841 tttagtactt tattattaat ttcagggcta ttatttttat ttttcttcaa agaaaatgaa
    12901 gaaattatac ctgaaagttc caatatttta acaatctcta attgggataa atctaacagt
    12961 aaatcaaaag tgttagatgt cattgaatca ggcgccaaaa atcaaaatat acaaataatt
    13021 aaatccgtta aagattttga taataaaaaa gaattttttg ttttcaactc aaaacgaaat
    13081 aattctgact ttatacgtaa taaaacatca cttttaactc catcagattt attaaacaga
    13141 gagataaaag gaaagtatta tattattggt gaacatttca atgtagaaga gcttacgagt
    13201 gaattaaaaa aagctggttt aacatctgaa gttgaataca taaatagaaa catattattt
    13261 tttgaattag tcatagataa tgatttatta gtgcctttca tattcttagg cgtattatat
    13321 cttttgtact tcttatatga cagaggatat aatttgaaat tttatgctat tcaaaagcta
    13381 catggctttt caactacacg cattattttt cataatattc atataaaaat catttattgg
    13441 ctagtactta ccgctatttt ctttattgct aatatattaa tcattcatat agccaattta
    13501 gaattggatt tcttaatgtt tattcgtaga tttatcgtgt tgctttttgt ttttgcttgt
    13561 attactacat tgctgtggct gatttcgtat agtcttcttt tgaagttaag tattccatta
    13621 atcttaaaag ggaaaaaagg atataagttt tcaatattta tgggtacctt caccaaatgt
    13681 atcatggtgc taatactatc ttttttactg gcacaaaatt taaatgctta tacgaagtta
    13741 aagaatatat atgactctga aaaaatctgg caaaagttag ataattacta tacattagag
    13801 atttctccta atattagaaa ttcagaagaa aaacaaattt tagaaactaa tatatacaat
    13861 ttaattaaga aaagcgaaca acttggtgga ttgcttttaa agaataataa tatagccaat
    13921 cccgataaaa acaattacat tcctgaaaat ggcaatgtct tttttatcaa taacaatttt
    13981 ctgaatttct ataaaaatat aaatcatgat tttaaaatga ttgacaatca ttcggataaa
    14041 ataaacgtgt ttattcctcc aaggttacaa tatcaaaaat ctgaaattca aaaaaatcac
    14101 caaggatgga ttgactttca aaagcaacaa aacaaaaaag tagatgtgca agtactgtca
    14161 aaaaacgtat ctgttttttc ttttgatcgc acaactaatt tgaaatttgg gtatctagat
    14221 tctccaatag taatgttgtt gacacttgac gatttaacag gagattttta tttagctgct
    14281 gtttctcaag gtggatatct atttaaagat ttagatacac ttaaacagtt gcttaaagat
    14341 aatcacctag aagaagaaat tagcggtata actaattaca aggattctgt gttaaatgaa
    14401 ttaaatgaaa cgaaaacaaa aatgataata acaatagtta ctattattat taacgttttc
    14461 attcttttga tagctactgt atttgaaaca attcaatatt ttagctggaa taaaaagcaa
    14521 ctattattaa gaaaaattca tggttattca ttattcagca gtaatgtacg ttatttaaca
    14581 atttctatct tactttctat tatgttagct tacactacgc atattttatt tggttcaaag
    14641 atattactat tcataataat gtctattgct attattcaac atttacttca aattgcttat
    14701 attaaatatc ttgaaaaata ctttaaagat ttaatgaggg agatttaaac aatgaaaaga
    14761 actttaatta ttgtaacaat tgtactatta atcatcatac ttagtctgtt attggttaga
    14821 aatgagcatt tagatcgttt taacccactg ttaaaagaaa aagtatctta tgccaaagtt
    14881 ccaaaagata cccaggacta tagaaatata actgtatact ctaaaaatgg agaaaaaaag
    14941 agttataaat tggatttttt aggttatgat cctacaaaag aatatgtgaa agtaaatcat
    15001 aaagggaaat atgtgcgttc gatagaatac attacaaaag atattcctag ctttttaaaa
    15061 tgaggtgacc gatagtgata aaacttgaaa atgtttttgt aaaaaaaggt aataaaaaca
    15121 ttttagacgg atgtaacttt aattttgaaa aaggaaaatc atatgcttta gttggagaaa
    15181 gtggcgctgg aaaatctact ttacttaaca taatcgctgg gttcgaagat gtatcacaag
    15241 gaagcatata tattgaagat aagttactaa aaaagaaagt cgatttttat agatatacgt
    15301 tagggtattt gtttcaaaat tttgctttac ttgaaaatca aacaatcagt caaaatttag
    15361 atttagccct aaagttcaaa aagaataaaa aagataatat gaacttaaag aaagaagtat
    15421 taaaaaaggt cggcctagat ttagatatca agagaattgt tagttctcta agcggtggtg
    15481 aacaacaaag agtagcattg gcaagattaa tattaaaaga tccgaaaatc attttagctg
    15541 atgaacctac tgggtcacta gatacgaaaa atggaaaaat agttattgat ttattattga
    15601 agctacttga tgaaaataaa actatgattg tcgtaacgca tgatttagag cttgcgaaac
    15661 gatttgatgt catagtcaat atttctgagc ttagaagtta agaaatattg ataggtatag
    15721 ccatacatag agaaaataaa aattatgaaa atatagatat tgatttaagt aagtcatatt
    15781 taaactatga tttagtcaat gatactaagt ttgattttaa taaaaaaaat tgatgagaaa
    15841 atcgaaaaaa attataaagg gaaacgcaaa attagaacag atgccattaa acatattgat
    15901 ggattaatta catcagataa tgtgtttttt aatcaattat ctgaagaaga gacaaaatag
    15961 ttttttaagc atgctaaagc gttcttggaa gaagaatacg gtaaagaaaa tcttttatat
    16021 gcgacagtac atatggatga gataacacca catatgcatt atggcgtagt tcctattact
    16081 aaagatggac gtttaagtgc gaaagaagtt gtaggtaata aaaaagcatt aaccgaattc
    16141 caagatagat tcaatacgta tattaataag caaggctatg atttaaaacg aggaatttct
    16201 agacaactta caaaagaaaa acatgatcaa gttagccgtt ataaacaaaa aacagaatat
    16261 cataaacaaa tgcatatgcg ctagaagcaa atagaggatt atttaaagca agaaaatgat
    16321 aaattgatac aaaactacca aaaatcatta gatacgctta aaaagcttct gagtgtcatg
    16381 tatgaaatta aaactaaaaa tgtaggtgga tggtttcata aagagaagca agaaacaggc
    16441 aatattgtaa ttactaaaac tgattttgaa aaatacacta aacaaattaa agcagcacag
    16501 atgatattag atgattatga atgtattaaa agtgggaagt cattaaaaaa agcagagaaa
    16561 caaaatgaaa gtttagttaa tgaattgact agtgtccata tggaaaatga aaagctggtt
    16621 gaagaattta atgatttagc acaacgttat aattatttgt tgtcagagaa tgaaaagaaa
    16681 gataaagaac taaattatac gcttaagtta ttcaatcaag tttttaaaat cattaaaagt
    16741 atgatgaaag aagagcgtta tcatacacta ataaatcata ttgataatca tttagacaat
    16801 tctaaaatac gtgaagtaat gacgatagat aacaatgatg aacagttctt taagaagaaa
    16861 tatcaagcac aagaacgaga aatcattttt aaagaagata gagaagatgg ttatacatta
    16921 taaaaataga tatttaaatg catttgtttg aggttaatta ttttttagga tgaaaaatag
    16981 gtagcccccc tcgaactttt taatatattt ttataaatct ttttaaaaac ctttttaggg
    17041 gcttgttcag ccctagagca acaagggatt tcaatgccta aaggagtgtt tttgccacat
    17101 aaaaggagtg tttttgccac ataaaaggag tgtttttgcc acataaaagg agtgtttttg
    17161 ccacataaaa ggagtgtttt aaaaagttgt actcctttta tggtttgaca ttgataataa
    17221 agtagtttat tgtgaataaa agttttcaaa tgggagtgta tattcaaacg atactccttt
    17281 aggttcgtaa taaagggggc tgtatcatga caggagagac agttgtatat aaaaatgaaa
    17341 tgaatttagt tccattaagg cgatttacag ctactgaaat taatttattt tttgcgatgt
    17401 gtaataaatt aaaagagcaa gatactaata cattacgttt gtcttttgat gaattaaaaa
    17461 aattaagtaa ttatagtcca gaaacacgta atattaatag atttgctaat gatttagata
    17521 atgtgtataa aaagatgttg aatttaacca ttagatatga agatgatgat gtaatagaaa
    17581 gattcgtttt attcaatcat tatagaatcc ataagcgaga acaatatcta gaaatatcaa
    17641 cttcttcaaa tttaaaacac atattgaatt caattactaa taattttaca aaatttgaat
    17701 taaaagaaat gactaggctt aaatctacat attctaaaaa tatgtttaga ttacttaaac
    17761 aatacaaaca tacaggctat ttaaaaattc acatcgatga ttttaaaaat cgtttagata
    17821 tacctaaatc ttatcgtatg actgatatta acaaaaatgt ttttaaacct attattattg
    17881 aattaggttc tatatttaat aatcttacta tcaataaaat caaagcgaaa aaagggcgta
    17941 aaattgaatg gatagagttc acatttgacg ctgagaaacg cattcataac aaacgacaac
    18001 ctcaaatgtc caagatagat aaatcaagac aatatgtgag gcgtgaaaag acgcctaaat
    18061 ggttagaaga acggtcatat gaaaagcaac ctcaaaaaga ttacgaccca caattagaga
    18121 aagaacgaga ggatttttta aaacaacttg aactgaattg ggaataacgc aacttttcgt
    18181 tgcgagttgg ttaactaaaa gtatcgtgac ttttcaatta ttttaattat agtttgagtt
    18241 aaggagtgat tttatgaaat tagctgaagc tataaaagaa cagagagaat taaaaggatg
    18301 gtctcaagag gaattagcca atatattaaa ggtttccaga caaagtgttt ctaaatggga
    18361 aagtgccaaa aactatcctt ccttagatat tttgattgct atgagcgatt tattcggaat
    18421 ctctttagag catttaatta aaggagatgc acgttttaaa aaagttattt tagagggaaa
    18481 ttatagagag agtaacaggg taccttccat agttgatttt ctttatgatt tttggtggct
    18541 tttctttcct gttgccggat ttttagtttg ggccattcat tcgttcatgg gttgatttta
    18601 aaatcaaaat ttaatgcaca tcaggcaata tgaaaaagga aagtattttt acgacacctt
    18661 gaaatgtatt gataagaata gaagagttta caaaaggcaa tatgaaatat atactaaaag
    18721 taacaagaat ttcgtttgta aacgcacaaa accccgaact attcgccgta gttcggggtt
    18781 ttttggtgaa ttggctttaa tcgtctatat tattttttat cacgtttatg gagctaataa
    18841 ccaaataacg taacgagaca accactgatt gccgttgtca tgatgtgaac aagaatttca
    18901 ttcataaatc gcacctcctc tctacgccga attgacatct gagagataga cgaccttcac
    18961 attataacaa atctctcctt ccatgaaata acatgaatat taataaatgt tgttatatat
    19021 taaagataaa taaatataag ggtgggattg ataatgtttg gcgatcaaag acaagaagct
    19081 acaaaatatg tcattaaaga aggttatcaa gatatttatt tcctcaacaa aaacggggaa
    19141 tggtattatt tcgaagtaag aagtgtctgg cgtggcaaac atattattag agttaaagat
    19201 ggtttgttag gttggagaaa agaaatagta actgaataaa gatacaaaat acttgccaat
    19261 gcaaaagaat gaaaacgcgt caaatcaacg atgtataaaa gatgcataaa agataatgaa
    19321 agtaaaaagc cataaatgcc gtcatatagg catttatggc tttttgtttg gttaacataa
    19381 tcgatgatta tcagaagttc aattcacata aaaaagcacg gctaatttat gaacttgtcg
    19441 taccttttta attaaaatta gttaccaaat agacgactcc aaaaaccctt tttaggttcc
    19501 gtttcttcac tcttttcttc tatatcacta tcattgtcat ttggattagc tgaaacgtct
    19561 tctctttgtg cttcttcacc ttgtgtactt tcgtcgcttt gacttccaga tatatcctta
    19621 tattgaatct ctgtttcttt agtttcttcc tgatctcggt taatatttac aggactagta
    19681 gtatatgttt tttcttgtgc atcaacgttt tgtctagcgt tagtagatgt atcaaaggga
    19741 taattaaggt gtttttcttt ttctaattga ttttctaatt tttgaatctt tttattactc
    19801 tctaatgcca gaacttgctg attctcaagc aattttgatc tttcttgcaa ctcttttctg
    19861 taaaattcaa ttgttgtttc atgacgactt tcttgttttt caatttgatt atttaaagta
    19921 ttaatctgat ttttaagtat ttctactatt tgagcatcgc ttttagattc aaaattaata
    19981 ttatccgact cttttttttg tttgtcttca gtagcacttt caaaaccata tttcttttta
    20041 ttttcattta ctctttgaat gattttttct atatcggtat cttctttaat aaacgaagtg
    20101 ttttcctgtt ttattgtctc tatattcaat ctcttaatat tattaaaaat cgtttgctta
    20161 ctaaccccta attcttcact caaccttttt acacttttca tatcatcaac cctttataaa
    20221 atgtttataa acccttagta aaatattata agcttataac gattaataat aaagtaatcg
    20281 acaaataaaa atataaattc gccaaccttt ttatcaaggg tttgtaaagg gtttatggtg
    20341 tttatcaaag gtttataaac ctatattttc ccttttttaa gtttattcaa agtgctataa
    20401 taaccttaat ataacaaaaa ccccaactac tggtaatagt cggggt
//
