LOCUS       NZ_CP137431            36664 bp    DNA     circular CON 04-NOV-2023
DEFINITION  Klebsiella pneumoniae strain KP82_L15_04.23_ST147_NDM5 plasmid
            unnamed3, complete sequence.
ACCESSION   NZ_CP137431
VERSION     NZ_CP137431.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37951967
            Assembly: GCF_033244325.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 36664)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Klebsiella pneumoniae ST147 - the rise of a multiresistant and
            hypervirulent type
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 36664)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-OCT-2023) HCAI, Fungal, AMR, AMU & Sepsis Division,
            United Kingdom Health Security Agency, 61 Colindale Avenue, London,
            London NW9 5EQ, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.9.1-b1780
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 62x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/03/2023 13:10:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,823
            CDSs (total)                      :: 5,699
            Genes (coding)                    :: 5,513
            CDSs (with protein)               :: 5,513
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 98 of 186
            Pseudo Genes (incomplete)         :: 92 of 186
            Pseudo Genes (internal stop)      :: 27 of 186
            Pseudo Genes (multiple problems)  :: 26 of 186
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP137431.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..36664
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP82_L15_04.23_ST147_NDM5"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed3"
                     /geo_loc_name="United Kingdom: England"
                     /collection_date="2023-01"
                     /genotype="ST147"
     gene            join(36277..36664,1..581)
                     /locus_tag="R5O55_RS00005"
                     /old_locus_tag="R5O55_00005"
     CDS             join(36277..36664,1..581)
                     /locus_tag="R5O55_RS00005"
                     /old_locus_tag="R5O55_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="WP_030005799.1"
                     /translation="MKDQITHLPDNADHSVAKQKFKITNWPTYNKALINRGSITFWLDD
                     EAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFTLMNVPLR
                     CPDYTSVSKRAKSVNVSFKTFTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     LHLAVDSNTHEIICANLSLNNVTDSEAFPGLIRQTHRKIRAASADGAYDTQLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRLTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5 family transposase"
     gene            complement(721..1107)
                     /gene="stbA"
                     /locus_tag="R5O55_RS00010"
                     /old_locus_tag="R5O55_00010"
     CDS             complement(721..1107)
                     /gene="stbA"
                     /locus_tag="R5O55_RS00010"
                     /old_locus_tag="R5O55_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001039464.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRQNRKNVLHNTHDKSSAKGAAESVLHNTQPSEPEVQESKKAESP
                     GIIDKEFFKKIGENFDPKKFNKKF"
                     /name="stbA"
     gene            1688..>1921
                     /locus_tag="R5O55_RS00015"
                     /old_locus_tag="R5O55_00015"
                     /pseudo=""
     CDS             1688..>1921
                     /locus_tag="R5O55_RS00015"
                     /old_locus_tag="R5O55_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(1954..>3468)
                     /locus_tag="R5O55_RS00020"
                     /old_locus_tag="R5O55_00020"
                     /pseudo=""
     CDS             complement(1954..>3468)
                     /locus_tag="R5O55_RS00020"
                     /old_locus_tag="R5O55_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            3534..4238
                     /locus_tag="R5O55_RS00025"
                     /old_locus_tag="R5O55_00025"
     CDS             3534..4238
                     /locus_tag="R5O55_RS00025"
                     /old_locus_tag="R5O55_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<4216..5502)
                     /locus_tag="R5O55_RS00030"
                     /old_locus_tag="R5O55_00030"
                     /pseudo=""
     CDS             complement(<4216..5502)
                     /locus_tag="R5O55_RS00030"
                     /old_locus_tag="R5O55_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220844.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /name="IS1380 family transposase"
     gene            complement(<5696..5902)
                     /locus_tag="R5O55_RS00035"
                     /old_locus_tag="R5O55_00035"
                     /pseudo=""
     CDS             complement(<5696..5902)
                     /locus_tag="R5O55_RS00035"
                     /old_locus_tag="R5O55_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            6066..6623
                     /locus_tag="R5O55_RS00040"
                     /old_locus_tag="R5O55_00040"
     CDS             6066..6623
                     /locus_tag="R5O55_RS00040"
                     /old_locus_tag="R5O55_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            6806..7666
                     /locus_tag="R5O55_RS00045"
                     /old_locus_tag="R5O55_00045"
     CDS             6806..7666
                     /locus_tag="R5O55_RS00045"
                     /old_locus_tag="R5O55_00045"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            7890..8495
                     /locus_tag="R5O55_RS00050"
                     /old_locus_tag="R5O55_00050"
     CDS             7890..8495
                     /locus_tag="R5O55_RS00050"
                     /old_locus_tag="R5O55_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            complement(<8528..8620)
                     /locus_tag="R5O55_RS00055"
                     /old_locus_tag="R5O55_00055"
                     /pseudo=""
     CDS             complement(<8528..8620)
                     /locus_tag="R5O55_RS00055"
                     /old_locus_tag="R5O55_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008438024.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA];
                     GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family transporter"
                     /name="SMR family transporter"
     gene            9155..10336
                     /gene="nhaA"
                     /locus_tag="R5O55_RS00060"
                     /old_locus_tag="R5O55_00060"
     CDS             9155..10336
                     /gene="nhaA"
                     /locus_tag="R5O55_RS00060"
                     /old_locus_tag="R5O55_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194048.1"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]; GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="WP_004194048.1"
                     /translation="MTENPIGLTRKVIKPVSNFFSSPVAGGIVLIIASAAAIIVANSPL
                     REGYETLLKYKTAGLSVEHWINDALMAVFFMMVGLEIKRELVTGQLATWSQRALPGFAA
                     LGGLAVPALIYVGFNAGHDETLSGWAIPAATDIAFALGVLALLGSRVPVSLKIFLSALA
                     ILDDMGAVAIIALFYTSNISLLMLGGAAAMVALLFSLNRAGVTRLLPYLLTGGVLWFFM
                     LQSGVHATVAGILLAFFIPLRTRNAADEVPLDRLEHAINPWVTFMILPLFGFANAGVAL
                     SGMTMNDLLSPVPVGVALGLFLGKQAGIFGLSLLAVSLGLAKRPEKSTWLQVYGVSVLC
                     GIGFTMSLFIGNLAFTGSPLLVDEVKVGVLAGSILAALAGILILRFAPSKQVR"
                     /name="nhaA"
     gene            complement(10763..11077)
                     /locus_tag="R5O55_RS00065"
                     /old_locus_tag="R5O55_00065"
     CDS             complement(10763..11077)
                     /locus_tag="R5O55_RS00065"
                     /old_locus_tag="R5O55_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000091613.1"
                     /translation="MSRSRRKTPIVGHTTCGSEREDKKLWHQRWRTRERTALTSASPEA
                     LSAHLPLLENQASSVWSMGKDGRSYWPVKRQAATADRIANHKGRNPQERASLKKRLLTL
                     "
                     /name="hypothetical protein"
     gene            complement(11332..11688)
                     /locus_tag="R5O55_RS00070"
                     /old_locus_tag="R5O55_00070"
     CDS             complement(11332..11688)
                     /locus_tag="R5O55_RS00070"
                     /old_locus_tag="R5O55_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003465043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="WP_000215515.1"
                     /translation="MTVESRIFSVAEYVQPSEGEPIRSVVLETRDSIIVVWHVHPGQEI
                     AAHIHPHGQDTWTVLSGMADYFQGNGIVRALREGEIAVARPGQVHGARNTGTEPFVLVS
                     VVASANAGFVLAER"
                     /name="cupin domain-containing protein"
     gene            complement(11678..12079)
                     /locus_tag="R5O55_RS00075"
                     /old_locus_tag="R5O55_00075"
     CDS             complement(11678..12079)
                     /locus_tag="R5O55_RS00075"
                     /old_locus_tag="R5O55_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="WP_001293886.1"
                     /translation="MSENRLPDYLDHIQQAATDARSFVEGMAKDDFLADKRTQQAVIMS
                     LIVIGEAATKVMDGYVEFTQAHADVPWRSMRNMRNRMAHGYFDINLDVVWETVQEWLPA
                     LLQQLPAVRQDADDEDRNDNCERGISDDC"
                     /name="DUF86 domain-containing protein"
     gene            complement(12076..12366)
                     /locus_tag="R5O55_RS00080"
                     /old_locus_tag="R5O55_00080"
     CDS             complement(12076..12366)
                     /locus_tag="R5O55_RS00080"
                     /old_locus_tag="R5O55_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="WP_001247892.1"
                     /translation="MRPSVVLDMKRSAVREAVGRFRAANPRVFGSVLHGTDRDGSDLDL
                     LVDALPGATLLDLGDLEEELKSLLGVDVDLLTPGDLPPKFRAKVLAEAQPI"
                     /name="nucleotidyltransferase"
     gene            12441..15413
                     /locus_tag="R5O55_RS00085"
                     /old_locus_tag="R5O55_00085"
     CDS             12441..15413
                     /locus_tag="R5O55_RS00085"
                     /old_locus_tag="R5O55_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834018.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element ISPa38 family transposase"
                     /protein_id="WP_032413488.1"
                     /translation="MPRRSILSAAERESLLALPDTKDELIRHYTFSESDLSIIRQRRGP
                     ANRLGFAVQLCYLRFPGVILGADEPPFPPLLRLVANQLKVGIESWDEYGQREQTRREHL
                     VELQTVFGFQPFTIGHYRQAVQLLTELAMQTDKGIVLARALIEHLRRQSVIVPALNAVE
                     RASAEAITRANRRLYDALAEPLTDVHRRRLDDLLKRRDNGKTTWLAWLRQSPVKPNSRH
                     MLEHIERLKAWQALDLPSGIERLVHQNRLLKIAREGGQMTPADLAKFEPQRRYATLVAL
                     AIEGMATVTDEIIDLHDRILGKLFNAAKNKHQQQFQASGKAINAKVRLFGRIGQALIEA
                     KQAGRDPFAAIEAVMSWDAFAESVTEAQRLAQPEDFDFLHRIGESYATLRRYAPEFLDV
                     LKLRAAPAAKDVLDAIEVLRSMNSDNARKVPTDAPTEFIKPKPRWQKLVMTDTGIDRRY
                     YELCALSELKNALRSGDIWVQGSRQFKDFEDYLVPPAKFASLKQASELPLAVATDCDQY
                     LHDRLTLLETQLATVNRMALANELPDAIITESGLKITPLDAAVPDTAQALIDQTAMILP
                     HVKITELLLEVDEWTGFTRHFAHLKSGDLAKDKNLLLTTILADAINLGLTKMAESCPGT
                     TYAKLAWLQAWHIRDETYGAALAELVNAQFRHPFAEHWGDGTTSSSDGQNFRTGSKAES
                     TGHINPKYGSSPGRTFYTHISDQYAPFHTKVVNVGVRDSTYVLDGLLYHESDLRIEEHY
                     TDTAGFTDHVFALMHLLGFRFAPRIRDLGDTKLYIPKGDATYEALKPMIGGTLNIKHVR
                     AHWDEILRMATSIKQGTATASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSV
                     ELRRRVHAGLNKGEARNALARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTV
                     YLERAANALRGHGQAVDDGLLQYLSPLGWEHINLTGDYLWRSSAKIGAGKFRPLRPLQP
                     A"
                     /name="Tn3-like element ISPa38 family transposase"
     gene            15492..16496
                     /locus_tag="R5O55_RS00090"
                     /old_locus_tag="R5O55_00090"
     CDS             15492..16496
                     /locus_tag="R5O55_RS00090"
                     /old_locus_tag="R5O55_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS4321 family transposase"
                     /protein_id="WP_000427620.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDRRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDNSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEIGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRDLLCRKSNFVVTCALANKLARIAWALTARQQTYVA"
                     /name="IS110-like element IS4321 family transposase"
     gene            complement(17044..18225)
                     /locus_tag="R5O55_RS00095"
                     /old_locus_tag="R5O55_00095"
     CDS             complement(17044..18225)
                     /locus_tag="R5O55_RS00095"
                     /old_locus_tag="R5O55_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4268 domain-containing protein"
                     /protein_id="WP_013023770.1"
                     /translation="MYKIDRQNNSLKSLMEVSFSSLGFRERDHLQEWLANNPQALTKKD
                     DKEDELLIIQKEFAGFDETNERLDLLAIDKKGNLVIIENKLDDSGRDVVWQALKYAGYC
                     ANLRQESVVEIFQLYLTQHEPSEIRPAAEVIAEFMGWESLKEGVLNRKGTQRVIMVAAN
                     FRKEVTNTALWLMQFGIRVQCFKATPYLFAEDVFVDIRQVIPTPEAESYMIGMAQKEAE
                     EQSTSSSSELQQRHYLRREFWSLALEKFRTSTCSLFNNRAPTTDHWLAAGSGVSGVPFE
                     VIFSQKDARIQLNISRSDAVENTWLFERLSERKTHIESQFGGMLNWRLLPERKSCQVVC
                     AKAFDGGNKELWPDIISWMIDGMTRLEKAIRPSLQELAVELKKSGLITEGGDE"
                     /name="DUF4268 domain-containing protein"
     gene            complement(18507..>18650)
                     /locus_tag="R5O55_RS00100"
                     /old_locus_tag="R5O55_00100"
                     /pseudo=""
     CDS             complement(18507..>18650)
                     /locus_tag="R5O55_RS00100"
                     /old_locus_tag="R5O55_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /name="IS110 family transposase"
     gene            complement(18666..19358)
                     /locus_tag="R5O55_RS00105"
                     /old_locus_tag="R5O55_00105"
                     /pseudo=""
     CDS             complement(18666..19358)
                     /locus_tag="R5O55_RS00105"
                     /old_locus_tag="R5O55_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            19542..20588
                     /locus_tag="R5O55_RS00110"
                     /old_locus_tag="R5O55_00110"
     CDS             19542..20588
                     /locus_tag="R5O55_RS00110"
                     /old_locus_tag="R5O55_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="WP_032413491.1"
                     /translation="MATYRAYYGQDRDREYFERIFQSANINFIIGSGASLPAISVLGDI
                     ESELEALVRAGNDDEYFSKSESFLDNVWKANNVLLKRSRPAEVILPTLIDDVVSTQNNY
                     AKLMRALEMLLTRRRTGLLPRRINLFTTNYDLFIEDAAVKNNNVILNDGFRQRADIYNR
                     TVFDAKCFYQTIHATGNLYNYSVELPTVNLIKLHGSLSWHSYDKEIYYSIKDMKPVAFN
                     TPKEKQGWVMSHQLVLPRKDKFRETLLENVYYDLLRTYSNELDKEGSLLIVFGFSFADE
                     HIETLTKKALRNATLKIVIFAYNEAAKDLFLGKFRDYSNVDVVFTPGAPLDFKKMNEII
                     TSFLGGMK"
                     /name="SIR2 family protein"
     gene            20585..22393
                     /locus_tag="R5O55_RS00115"
                     /old_locus_tag="R5O55_00115"
     CDS             20585..22393
                     /locus_tag="R5O55_RS00115"
                     /old_locus_tag="R5O55_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572050.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_032413492.1"
                     /translation="MTSAFVNEEAVLRIGEVREVSGRTLSVLVDKNKNLSDLFYHGKVL
                     KNVSVGSFIEVKKGFMSLIAKVETEKIVEEKSPVGSGSDSLRFRRYLTASLAGYIDRNG
                     RFTGGTRELPLIGNEVFLMSEEQLHLIHSIAPAGESGLNFSRTDLEDIDITLPISGLLN
                     SHIAIFGNTGSGKSNTLAALYQHGYEALKNLLGEGFRSRSRFLLFDFNGEYGGRSCITR
                     DKVVYNLSTHDEEGDRIPMPAEILLEHEILSVLTDATDKTQKPFLKRVLEFKKRVESKL
                     NPQSYFREILKRRVTETLFGCEKKKSDDLIDLFRPVLKDEDLIADIEFFYNNGGVWRTK
                     TGVYFSNEENTHQCNMYQRAQNYEFPEDIMEELLDYMYVQLIIEYLSSRSNPEHLSPVI
                     NRMSGLKKDIRKIFNTASGGTIWAETNFVVLNLNMVNLTMKKTLPLLMAKWAYSAKKMD
                     KVPSTLHLIIDEAHNILSNTSFRESESWKDYRLETFEEIIKEGRKFGVFVTISSQRPND
                     ISPTIISQAHNYFIHRLINQNDLYAIEKSVSYIDRMTEESIPTLATGTCIFSGVICPMP
                     LKLRINELSFRKKPHSHTLNFEDLML"
                     /name="ATP-binding protein"
     gene            <22629..22874
                     /locus_tag="R5O55_RS00120"
                     /old_locus_tag="R5O55_00120"
                     /pseudo=""
     CDS             <22629..22874
                     /locus_tag="R5O55_RS00120"
                     /old_locus_tag="R5O55_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            23018..23368
                     /locus_tag="R5O55_RS00125"
                     /old_locus_tag="R5O55_00125"
     CDS             23018..23368
                     /locus_tag="R5O55_RS00125"
                     /old_locus_tag="R5O55_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000493378.1"
                     /translation="MFTAFNERNDFSYAFEKIRNAISAPGENNLYAATELGLGILLRKY
                     EQFRQELDAAGELGNWEYDLDTYNHCIAVLQRYFTGNPSGLTERDARIYSHYLQTEHKR
                     FVKLAEELAAGR"
                     /name="hypothetical protein"
     gene            23419..24162
                     /locus_tag="R5O55_RS00130"
                     /old_locus_tag="R5O55_00130"
     CDS             23419..24162
                     /locus_tag="R5O55_RS00130"
                     /old_locus_tag="R5O55_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000129823.1"
                     /translation="MTDIQAATESIVAATSHPVSVQLINQGAGIWGNVATGLITGLLTG
                     GITLTGIWLTHYFTLKRERQASEDKMKKELHYIATELVFMLERYAEGCFRVVTDDGQDD
                     DAPQPERKAVTNYPELNLIDVSGDWRTLEPRLMYRIRELPVLQDEAHRAIAYAAEYSDP
                     PWHKDYFRERQYQFTRLGINAVILAVRLRKATGMPETRLTGHDEWSAVSVFRKVWRRER
                     ALRAAEATRNREWNQLVIPDGMSNQ"
                     /name="hypothetical protein"
     gene            24159..24935
                     /locus_tag="R5O55_RS00135"
                     /old_locus_tag="R5O55_00135"
     CDS             24159..24935
                     /locus_tag="R5O55_RS00135"
                     /old_locus_tag="R5O55_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_000015958.1"
                     /translation="MSGLLSYSHPQQPAQMPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLVPPYPFVQLATLKQRTEK
                     AARTAGRAPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRTEKARIWDIT
                     DRTVRTWIGEAVEAAAVDGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFQMPEADAVAMLKGNI"
                     /name="site-specific integrase"
     gene            complement(24993..25250)
                     /locus_tag="R5O55_RS00140"
                     /old_locus_tag="R5O55_00140"
     CDS             complement(24993..25250)
                     /locus_tag="R5O55_RS00140"
                     /old_locus_tag="R5O55_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000764642.1"
                     /translation="MKLETIQIDNTVRSGLNSFTDGVIIRDTKVLITLNLPDGQKTTIE
                     GEWRHMSDANRLSERITMLQHAIYEQYEEYRADIPVSWSR"
                     /name="hypothetical protein"
     gene            complement(25379..25483)
                     /locus_tag="R5O55_RS00145"
                     /old_locus_tag="R5O55_00145"
     CDS             complement(25379..25483)
                     /locus_tag="R5O55_RS00145"
                     /old_locus_tag="R5O55_00145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032409716.1"
                     /translation="MRSFTIMSLLETFLTASQGATILFLAMLIYWQKR"
                     /name="hypothetical protein"
     gene            26013..26879
                     /locus_tag="R5O55_RS00150"
                     /old_locus_tag="R5O55_00150"
     CDS             26013..26879
                     /locus_tag="R5O55_RS00150"
                     /old_locus_tag="R5O55_00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004118283.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_004118283.1"
                     /translation="MGKRSSSVLNYPLVDKVQIFPVDKYRDSLQFLFSLSLWVGKNLPI
                     GIEMDTQALLPATKTFKKRASIKQSNELTEAAYYLPLQAKRVLWLCLMQAYFNDSQEDD
                     SDVLPLFKISVSDYVKYFNVATSVASRDVKAGVNALGESTVTFYPKEGEFEEVKRPWLA
                     EAGMKRGRGSWQIEFNYKVMPFLVGLTSQFTTYSLYDCGQLNSVRVIRLYESLCQFRST
                     GVWITTHDWLCERFMLPASQKNNIAEMKRTFLEPALKKINEKTPLKVTYTTEEDGRLLF
                     NFLDKKQ"
                     /name="replication initiation protein"
     gene            complement(27056..27325)
                     /locus_tag="R5O55_RS00155"
                     /old_locus_tag="R5O55_00155"
     CDS             complement(27056..27325)
                     /locus_tag="R5O55_RS00155"
                     /old_locus_tag="R5O55_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000339857.1"
                     /translation="MDAPDYGKQVNFADGPDYGKQVNFTGGRECGEQVNFADGPDYGKQ
                     VNFAGGRDCGKQVNFADGPDCGKQVNFAGGRECGEQVNFADGPD"
                     /name="hypothetical protein"
     gene            27740..28945
                     /locus_tag="R5O55_RS00160"
                     /old_locus_tag="R5O55_00160"
     CDS             27740..28945
                     /locus_tag="R5O55_RS00160"
                     /old_locus_tag="R5O55_00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000368714.1"
                     /translation="MDNIEQLRKVATRAGKLLTSLSESIRQQKEELKLTEFYQEYSKAA
                     LYKLPKLSKGSVEYAVSEMEAGGYIFKKKPSGNTMKYAMTIQNVIDLYNHRKVPKYRDR
                     FDKAFTIFVCNLKGGGSKTVSTASLSHAFRAHPQLLFEDLRILAIDFDPQASLTMFLSH
                     ENSVGLVENTAAQAMLQNVSREELLSDFIVPSIIPGVDVIPASIDDAFLAEGWKGLCEE
                     HLPGKNIHAVLKENIIDKLQHDYDFIFLDSGPHLDAFLKNCIGAADLMLTPLPPATVDF
                     HSSLKFVASLPALIDSIEMDGHTCNLIGNVGFMSKILNKSDHKICHSQAKEVFGADMLD
                     MVLPRLDGFERCGETFDTVISANPATYDGSTEALKSAKSAAEDFAKAVFDRIEFIRTNG
                     GM"
                     /name="AAA family ATPase"
     gene            28945..29919
                     /locus_tag="R5O55_RS00165"
                     /old_locus_tag="R5O55_00165"
     CDS             28945..29919
                     /locus_tag="R5O55_RS00165"
                     /old_locus_tag="R5O55_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB family protein"
                     /protein_id="WP_000064119.1"
                     /translation="MSNEKRKTIGRQLNTQASIAEMTDTGRSQVFTLKTGRKVTFRFVR
                     VPASEVESKTFVNQENNGRDQLALTRESLKSIIQTIKFQQFFPCIGIKQSERIEILDGS
                     RRRASAIFVRTGLDVMVTEEHLSADEARQLAKDIQTAKEHNLREIGLRLIALKESGFNQ
                     KEIAELEGLSQAKVTRALQAAAVPQDLISLFPVQSELSFSDYKLLLEVNEKLSEKGLTP
                     EELIQSVSAQLDAILSEGERPEDEQKASILKLISQASQALIDPSPKEKSVVSPLWSFEE
                     KDKFARKRVKGRTLTYEFSRMSKVIQDELDKAINEVLDRNLSQ"
                     /name="ParB family protein"
     gene            complement(30001..31272)
                     /locus_tag="R5O55_RS00170"
                     /old_locus_tag="R5O55_00170"
     CDS             complement(30001..31272)
                     /locus_tag="R5O55_RS00170"
                     /old_locus_tag="R5O55_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_001754953.1"
                     /translation="MFALADVNSFYASCERVFRPDLKGKPIVVLSNNDGNVIARSAEAK
                     PWIKMETPWFQIKNERYPEKIYAFSSNYELYASMLARVMNSLEELAPRVEQYSIDEMFL
                     DLTGVEHCMELEDFGRQLRQHVYDCTHLTIGVGAGPTKTLAKSAQWASKEWKQFRGVLA
                     LTRGNPQRTRKLLSLQPVEEIWGVGNRIARKLNVLGIKTALDLALTNPAFIRKNFSVVL
                     ERTVRELNGESCLSLEEAPPTKQQIVCSRSFGVKITEYESLRQAICQHAERASEKLRKE
                     HQYCRHISVFIKTSPFAIKEPYYGNVATEKLLTPTQDTRDIIAAATTALERIWRDGHRY
                     AKAGVMLNDFTGSGVSQLQLFDERPPRPYSAELMKVLDGINNSGLGKVWFAGRGIAPEW
                     QMKREMLSPAYTTRWSDIPSAKLA"
                     /name="Y-family DNA polymerase"
     gene            complement(31272..31703)
                     /gene="umuD"
                     /locus_tag="R5O55_RS00175"
                     /old_locus_tag="R5O55_00175"
     CDS             complement(31272..31703)
                     /gene="umuD"
                     /locus_tag="R5O55_RS00175"
                     /old_locus_tag="R5O55_00175"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229772.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="WP_000776034.1"
                     /translation="MKLQLFSTGKELPPQAHPLFADLASCGFPSPAADYVESDLDLHDY
                     CIRHPSATYYLRASGDSMADGSLYNGDLLVVDSAEKPRHGDIVVASMQGEFTVKRLLLT
                     PRLTLQPMNASWSPIYPDPDELDIFGVVTHIIHRPREMY"
                     /name="umuD"
     gene            32109..33596
                     /gene="ltrA"
                     /locus_tag="R5O55_RS00180"
                     /old_locus_tag="R5O55_00180"
     CDS             32109..33596
                     /gene="ltrA"
                     /locus_tag="R5O55_RS00180"
                     /old_locus_tag="R5O55_00180"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_023300763.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRSVIRLIRKWLTAGTLEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            33748..34445
                     /locus_tag="R5O55_RS00185"
                     /old_locus_tag="R5O55_00185"
     CDS             join(33748..33997,33997..34445)
                     /locus_tag="R5O55_RS00185"
                     /old_locus_tag="R5O55_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558268.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1X3 family transposase"
                     /protein_id="WP_223229472.1"
                     /translation="MASISISCPSCSATEGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYGRMCRTVVARVFGERTLATLERLPGLLSAFEVVVW
                     MTDGWPLYESRLKGELHVISKRYTQRIERHNQNLRQHLARLGRKSLSFSKSVALHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1X3 family transposase"
     gene            <34455..34763
                     /locus_tag="R5O55_RS00190"
                     /old_locus_tag="R5O55_00190"
                     /pseudo=""
     CDS             <34455..34763
                     /locus_tag="R5O55_RS00190"
                     /old_locus_tag="R5O55_00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561120.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     ARG             6807..7663
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          1334..1591
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.273"
                     /coverage="96.0"
                     /evalue="7.34e-49"
     Typing          26014..26908
                     /name="IncR"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.442"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcgcgcatct ggtgattgat tccaccgggc tgaaggtctt tggtgaaggc gaatggaaag
       61 tcaaaaagca tggccaggaa cgccgtcgta tatggcgaaa gttgcatctg gcagttgaca
      121 gcaacacaca tgaaatcatc tgtgcaaacc tgtcgctgaa caatgtgacg gactcagaag
      181 ccttcccggg tcttatccgg cagactcaca gaaaaatcag ggcagcatcg gcagacggcg
      241 cttacgacac ccaactctgt cacgatgaac tgcggcgtaa gaaaatcagc gcgcttatcc
      301 cgccccgaaa aggcgcgggt tactggcccg gtgaatatgc agaccgtaac cgtgctgttg
      361 cgaatcagcg gctgaccggg agtaatgcgc ggtggaaatg gacaacagat tacaaccgtc
      421 gctcgatagc ggaaacggcg atgtaccggg taaaacagct gttcggaggt tcactgacac
      481 tgcgtgacta cgatggtcag gttgcagagg ctatggccct ggtacgagcg ctgaacaaaa
      541 tgacgaaagc aggtatgcct gaaagcgtgc gtattgcctg aaaacacaac ccgctacggg
      601 ggagacttac ccgaaatctg atttattcaa caaagccgcg cggggctaac aggtaagatg
      661 aaattaaggt tttacgaaca ctgccactgt aattaattac cgctactttc ataaatcacc
      721 tcagaatttt ttgttgaact tcttagggtc gaaattctca ccgattttct tgaagaattc
      781 tttatcaata atgccgggac tctctgcttt tttactttcc tgcacttcag gctcagacgg
      841 ttgtgtattg tgcaatacac tttccgctgc acccttcgcg ctactcttat catgcgtatt
      901 gtgcaataca ttttttcggt tttgccgcgt tctatacagt gccatctcaa gccctttggc
      961 tgttaccgaa aagctgtatt cgctgtcgag gatttcagca atttcatgcc gcgttagccc
     1021 tctgtccagc cagttctcga tttcatttag gcgcaatctg acagcagccg ataagttgcg
     1081 gggtttcaga tctgctggtt tattcataac cccctccgtt gtatgaaaat gactctacaa
     1141 cactcgtaag aaggggtcaa tcgagttttg tagtttatct gtagttttat tgtagtctat
     1201 ttgtagtctg tcacgttttt tgtagtttat ttgtagtttt attgtagtct atttgtagtc
     1261 ttacaacact aaggcaaaac gttttttgta gtttatctgt agtttatctg tagtttttgg
     1321 ttgctcagat ggtcatgcaa gcatgaccat caaagaatag gacgcttttt agccaaatgc
     1381 cccttaacct acggagatcg ccctaccaaa aaaagatgat tttttatccc ttaacctgct
     1441 atacacctaa cgcagcgtga taaatcacgc tatcgcactg atttaaaaga aaaaaaacaa
     1501 aatttagcca tgctgcggta ttacccaggt attacaaatc aaatctaaat tactgattta
     1561 aataactttt tatttattac tttggtaata ctatgatttc accgtattag acaccctttt
     1621 ttcgtttaaa aaatgcacaa attgaggact gaatgggctt tgttgaataa atcgaacttt
     1681 tgctgagttg aaggatcaga tcacgcatct tcccgacaac gcagaccgtt ccgtggcaaa
     1741 gcaaaagttc aaaataacca actggcccac ctacaataaa gccctcatca accgtggctc
     1801 cataactttc tggctggatg atgaagctat tcaggcctgg tatgagtcag caacaccttc
     1861 ttcacgaggc agacctcagc gctattctga ccttgccatc acgactgtgc tggtcattaa
     1921 ggggagcccg cagaattcgg aaaaaatcgt acgctaaggt tttccgggca tccgtaaggg
     1981 ccgaaacttc ccgtcttcca gtctgcggct ctgccgccag acgtaatcgc cggttaggtt
     2041 gatgtgctcc cagcccagcg gcgacaggaa ttgcagcagc tcgccgtcca ccggcttgcc
     2101 ggcctcgacc aacccctggg tggcgcgttc caggtacacc gtgttccaca gcacgatagc
     2161 cgccgtcacc aggttgaggc cgctggcccg gtagcgctgc tgctcgaagc tccgatccct
     2221 gatttcccca aggcggttga agaacaccgc cctggccagc gagttgcgcg cctcaccttt
     2281 gttcaggccg gcatgcacgc ggcggcgcag ttcaacactt tgcagccagt ccaggatgaa
     2341 cagcgtgcgc tcgatccggc ccagctcgcg cagggccacg gccagtccgt tctggcgcgg
     2401 gtagctgccg agcttgcgca gcatcagcga ggcggtgacg gtgccctgct tgatcgagct
     2461 ggccaggcgc aggatgtcgt cccagtgggc acgcacgtgc ttgatgttca gggtgccgcc
     2521 gatcagcggg cgcaacgtcg ggtaggcttg cacgccctgc ggcacgtaca gcttggtttc
     2581 gccgaggtcg cggatgcgcg gcgcgaagcg gaagcctagc aggtgcatca gggcaaagac
     2641 gtgatcggtg aagccggccg tgtcggtgta gtgctcctcg atccgcaggt cggactcgtg
     2701 gtacagcagg ccgtcgagca cataggtgga atcgcggacg ccgacattca ccacgcgggt
     2761 gctgaacggc gcgtactggt cggagatatg ggtatagaac agccgtcccg gctcgctacc
     2821 gtacttcggg ttgacgtgcc cggtgctctc gccccggcca cccgcgcgga agcgctggcc
     2881 atcggaggat gaggtcgtgc cgtcgcccca gtgggcggca aaggcgtggc gatactggtg
     2941 gttgaccagc tcggccaagg ccgccgaata ggtttcgtcg cggatgtgcc aggcttgcag
     3001 ccaggacagc ttggcgtagg tcaggccggg gctcgactcg gccatcttgg tcagcccgag
     3061 gttgatcgca tcaccgagga ttgcggacag cagcaacgtc ctgtctttgg cctcggcccc
     3121 gtccttcaag tgggtgaagt ggcggctgaa gcccgtccag tcgtccacgt ccatcagcag
     3181 ttcggtgatc ttgatgcgcg gcagtaactg gctggtttgg tcgatcagcg cctgcgcccg
     3241 atccggcacc gccgcatcca gcggggtgat tttcagccct gactcggtga ggatggcatc
     3301 gggcagctcg ttgtccttgg ccaggcgggt gacggtggcc aactgctcgt ccagcagctg
     3361 caaacgctct tccaggtact ggtcgctgtt cgggttgatc gccaggggca gggcctgctc
     3421 gcgcttgagt gcggcgaact tctcggccgg cagcaggtag tcgtcgaagt ggcactgttg
     3481 caaatagtcg gtggtgataa acttatcatc cccttttgct gatggagctg cacatgaacc
     3541 cattcaaagg ccggcatttt cagcgtgaca tcattctgtg ggccgtacgc tggtactgca
     3601 aatacggcat cagttaccgt gagctgcagg agatgctggc tgaacgcgga gtgaatgtcg
     3661 atcactccac gatttaccgc tgggttcagc gttatgcgcc tgaaatggaa aaacggctgc
     3721 gctggtactg gcgtaaccct tccgatcttt gcccgtggca catggatgaa acctacgtga
     3781 aggtcaatgg ccgctgggcg tatctgtacc gggccgtcga cagccggggc cgcactgtcg
     3841 atttttatct ctcctcccgt cgtaacagca aagctgcata ccggtttctg ggtaaaatcc
     3901 tcaacaacgt gaagaagtgg cagatcccgc gattcatcaa cacggataaa gcgccagcct
     3961 atggtcgcgc gcttgctctg ctcaaacgcg aaggccggtg cccgtctgac gttgaacacc
     4021 gacagattaa gtaccggaac aacgtgattg aatgcgatca tggcaaactg aaacggataa
     4081 tcggcgccac gctgggattt aaatccatga agacggctta cgccaccatc aaaggtattg
     4141 aggtgatgcg tgcactacgc aaaggccagg cctcagcatt ttattatggt gatcccctgg
     4201 gcgaaatgcg cctggtaagc agagtttttg aaatgtaagg cctttgaata agacaaaagg
     4261 ctgcctcatc gctaactttg caacagtgcc cttcatgatt acatatcttg cggttttgat
     4321 tatttttgct gcaagaaata catacttcaa acgaaaggtc tttatttgct gtctgtattc
     4381 tgaagagtcc aaggaatcaa acttgaacaa caaaaatagg ttatatgaaa gcatcatcat
     4441 ttgaaacacg gcttcattcg cccaaaatga ctttagcaag agatgaccca ccgccatgtc
     4501 gtatttggct tctttgatat agttttcagc attaccacgc ttttcatagt atataactac
     4561 tttttcagaa agcaaggtag tatttgttac aaagaaaaag tagtcgtatt cggaaccttc
     4621 taaaagtgat aattgtgctc tttctttttc tggtttcagt acgcgagata cgacaaatct
     4681 tctgtctttt tcccatttaa ctaattttgt atacagttct gtagtttctc taccttcttc
     4741 tcctttaacg aatacaattg atgaattcgt tgcttgtgag gtgagtgtag aataactttt
     4801 ggctttaatt aaatatttgc atccaagaga ttctatcgtt tcgataattt tttcatcaaa
     4861 gtagccacta tccattcgaa ataaaatttc taaatcgtct gatttgatgt tagcaacaat
     4921 ttctttgatc atttccgcag caccgtttgc agtgtaagta ttgccacttc ttacaaatcc
     4981 ggtaacatat gcttttaatt cgtcgcaaaa tgcaaattgg atattgtagc atcggtttcc
     5041 cagtttctta ggattatatc cttttgacgc accttcttga tgaccttcta cgttaattac
     5101 actactatca atatcaatcg taatggatgt caatttactt ttagtgagca gttttttaaa
     5161 gactttaaaa ttaatgtctc taaacatttg ggttgtcttg aagttgaagt ttcctagaaa
     5221 ccgtgacact gtttcaggtt cttttacgga aatatcaaac tcgttgacga ggggatcatt
     5281 ttgaagtagc tttagacgtt ctaacttatc aatgccaatg aagtgaccgc agagcatggt
     5341 ctttatatga ttcatcttga ttttatttgt tgagtcatta tcaaatacga ggtcattttc
     5401 aataaaatca aaaatcccat tgctttttgc attctcaagg agcagaaaaa gacctgcatt
     5461 tgatgttaga ttcttagctt tgaaatcaat tttattaatc ataattagaa ccccttttta
     5521 ctacttttct tactattatt ttaccatata tcgagtcata aaagctgata atttaacata
     5581 tttttgagca cttttctttc acccaatggg tgaaagctga atttcgaagg aatgcatatt
     5641 tatcaaggct ttgattatgc tttttgaagt actgacgtag aatctaggta tgattcatat
     5701 cggtgaggaa ggtgcccaga aaacggacac atccaatttg cagggcaatg cccagacggt
     5761 tgtgatcacc tctgcttttt ccgataaatt ccttgtctgc ttcatcaagg tgaaaatatc
     5821 gtgccagctg aagctcatcc ggttcaccgg tgaatctgcc atagctttca gtctgctcag
     5881 tggtcagaaa gtcaacgggc atatcggcct ccctgcctga cgggcattta gtaacatttt
     5941 tccaaccgta cgaaatgtta taaattatca gacatagtaa aacggcttcg tttgagtgtc
     6001 cattaaatcg tcattttggc ataatagaca catcgtgtct gatattcgat ttaaggtaca
     6061 tttttatgcg aatttttggt tatgcgcggg tctcaaccag ccagcagtcc ctcgatattc
     6121 agatcagagc gctcaaagat gcaggggtaa aagctaaccg catctttacc gacaaggcat
     6181 ccggcagttc aacagatcgg gaagggctgg atttgctgag gatgaaggtg gaggaaggtg
     6241 atgtcattct ggtgaagaag ctcgaccgtc ttggccgcga caccgccgac atgatccaac
     6301 tgataaaaga gtttgatgct cagggtgtag cggttcggtt tattgacgac gggatcagta
     6361 ccgacggtga tatggggcaa atggtggtca ccatcctgtc ggctgtggca caggctgaac
     6421 gccggaggat cctagagcgc acgaatgagg gccgacagga agcaaagctg aaaggaatca
     6481 aatttggccg caggcgtacc gtggacagga acgtcgtgct gacgcttcat cagaagggca
     6541 ctggtgcaac ggaaattgct catcagctca gtattgcccg ctccacggtt tataaaattc
     6601 ttgaagacga aagggcctcg tgatacgcct atttttatag gttaatgtca tgataataat
     6661 ggtttcttag acgtcaggtg gcacttttcg gggaaatgtg cgcggaaccc ctatttgttt
     6721 atttttctaa atacattcaa atatgtatcc gctcatgaga caataaccct gataaatgct
     6781 tcaataatat tgaaaaagga agagtatgag tattcaacat ttccgtgtcg cccttattcc
     6841 cttttttgcg gcattttgcc ttcctgtttt tgctcaccca gaaacgctgg tgaaagtaaa
     6901 agatgctgaa gatcagttgg gtgcacgagt gggttacatc gaactggatc tcaacagcgg
     6961 taagatcctt gagagttttc gccccgaaga acgttttcca atgatgagca cttttaaagt
     7021 tctgctatgt ggcgcggtat tatcccgtgt tgacgccggg caagagcaac tcggtcgccg
     7081 catacactat tctcagaatg acttggttga gtactcacca gtcacagaaa agcatcttac
     7141 ggatggcatg acagtaagag aattatgcag tgctgccata accatgagtg ataacactgc
     7201 ggccaactta cttctgacaa cgatcggagg accgaaggag ctaaccgctt ttttgcacaa
     7261 catgggggat catgtaactc gccttgatcg ttgggaaccg gagctgaatg aagccatacc
     7321 aaacgacgag cgtgacacca cgatgcctgc agcaatggca acaacgttgc gcaaactatt
     7381 aactggcgaa ctacttactc tagcttcccg gcaacaatta atagactgga tggaggcgga
     7441 taaagttgca ggaccacttc tgcgctcggc ccttccggct ggctggttta ttgctgataa
     7501 atctggagcc ggtgagcgtg ggtctcgcgg tatcattgca gcactggggc cagatggtaa
     7561 gccctcccgt atcgtagtta tctacacgac ggggagtcag gcaactatgg atgaacgaaa
     7621 tagacagatc gctgagatag gtgcctcact gattaagcat tggtaactgt cagaccaagt
     7681 ttactcatat atactttaga ttgatttaaa acttcatttt taatttaaaa ggatctaggt
     7741 gaagatcctt tttgataatc tcatgaccaa aatcccttaa cgtgagtttt cgttccactg
     7801 agcgtcagac cccaagtata gtctgttttg gacaacagcc agcccatata aatcagggcg
     7861 ttccgataca aaaatccagg agggttcaat tgggacatcg tgccgccatt tactgccggg
     7921 tttcaacagc ggatcagtct tgtgaacgcc aggaatttga tctgcgagcc ttcgccggcc
     7981 gtgccggcta cgacgtggtg ggaatattta aggaaacagg ttcaggaact aaactcgacc
     8041 gggccgagcg aaagaaagtc ctggcgcttg cccagtccag acaaattgat gcaatcctgg
     8101 tcactgagct ttcccggtgg gggcgctcga cgctcgatct gctcaatacg ctacgtgaac
     8161 tggagaactg gaaggtttcc gtgatagcca tgaatggaat ggcgttcgat ctttcgtcgc
     8221 cgtatggacg aatgctggcg acgtttcttt ccggcattgc ggagtttgag cgggatctca
     8281 tcagcgagcg ggtcaagtca ggccttgctg ttgcgaaggc acgtggtaag aggcttggtc
     8341 gtcaggccgg agtgcgacca aaatcagacc gacttttgcc taaggtggtt gcgatgaggg
     8401 ccgagggacg cagctatcgc tggatcgcac gcgagctcgg tatcagcaag aataccgtcg
     8461 ctgacatcgt gcaacgacac agagctaacg cttagggtgt catttcgccc tcagccggaa
     8521 ccgaccccgg ccataaccgg gtgaacccgt cggtccgcgg aatggccgcc gcgtaaaaga
     8581 tctcacagca tccggcaagc aataaatata tccagcccaa aacttctggc ctcagtgtta
     8641 acgaaatgcg ccattttgac ctgtggtatg tcttttctga cagccattcg tcaccggcat
     8701 ggacggataa ttatccatca gctgctgttc aggcttttca ggataatgcg gctcagagca
     8761 gcatctgtct gcaaacggtg tcctgtgtaa tcattttcca tcactacccg tgtcagttta
     8821 cgttgccagc tcttactgac agatactatt tactgacacg cggcggatag taaatttcag
     8881 ccatgttctg gaaacagact gagcaaattt ctcagaatgg aaacgcaccc tagccccgcc
     8941 aaggcttcgc tttacgataa tttacctgaa ggcggccatt tacctgacgg tgcatgataa
     9001 aatgtaacca cagaccgacc gaatttaact tattaattta attatctaaa tttcttacat
     9061 cagtcaatca ggctgtgcat tgcatttttg gagtgcacag tctctgggtt gcctgattca
     9121 caattcgtaa gtcaacatct cagggggaga ttaagtgaca gaaaacccaa tcggattaac
     9181 cagaaaagtt atcaagcccg tttctaattt tttcagttca cctgtagcgg gcggtattgt
     9241 gcttattatt gcttcggcag ccgctatcat cgtggccaat tcgcccctca gggaaggtta
     9301 tgaaacactc ctgaaataca aaacagcagg cctgtccgtt gagcactgga taaacgatgc
     9361 cctgatggcc gtattcttta tgatggtcgg gctggaaatc aagcgtgagc ttgtcaccgg
     9421 ccagttagcc acctggagcc agcgtgcgtt gccgggcttt gccgcactgg gtggtctggc
     9481 cgtacctgcc ctgatttacg tggggtttaa tgccggtcat gacgaaaccc tttccggctg
     9541 ggccatcccg gcggccacgg atattgcttt tgcgctcggt gtactcgcct tactgggcag
     9601 tcgtgtgcca gtctcgctaa aaattttcct gtcggcgctg gctattctgg atgacatggg
     9661 ggcggtggct atcatcgcgc tcttctatac cagcaacatt tcgcttctga tgctgggtgg
     9721 tgcagcggca atggttgctc tgctgtttag cctgaaccgt gccggcgtga cgcgcctgct
     9781 gccctatctg ctgacggggg gagtactgtg gtttttcatg cttcagtcag gcgtgcatgc
     9841 caccgtcgcg ggtatcctgc tggcgttctt tatcccgctg cgaaccagga atgcggctga
     9901 tgaagtgcct ctggacaggc ttgagcatgc catcaacccc tgggtcacgt ttatgatact
     9961 gccgctgttt ggcttcgcca atgcgggcgt cgcgttgtcg ggcatgacga tgaatgacct
    10021 gttgtcgccg gttccggtag gcgtggcgct gggcctgttt ttgggtaaac aggcaggtat
    10081 ctttggcctg tcgctactgg ccgtcagcct gggcctggcg aaacgaccag agaaaagtac
    10141 ctggttacag gtttatggtg tctcggtact gtgtgggatt ggttttacca tgagcctgtt
    10201 tatcggcaat ctggccttta caggcagccc tctgctcgtt gatgaggtca aggtgggggt
    10261 tctggcaggg tccatactgg ccgctctggc cggtattttg atactgcgct ttgcgccttc
    10321 taagcaagtc aggtaacgta ttatctacag gaaaatcccc gtgataacgg gggttttttc
    10381 acactgtcag tgtatattct gaagagaaaa ttgaaattat ttaattttat tataaataat
    10441 tacctttcta tctttcacat tttacaggcg gagccctgtt cagataagtc aggatgaacg
    10501 ctggcatatc agttaaaata ttatgttatt caaataaata gtcggctaac gtggtttttt
    10561 acacgactgg ccctctaacc ccgctactga atactgaccg ccaaaaggcg gtttttttgt
    10621 tcaaagaaac tgatctcagt atcgcgcccg gggcagctgg ccaacgtcgc cggcatcgcg
    10681 ccggcaaaaa tcgaaaaaca gaaatatcag caagatagct taaacaggtg tcgggaaatt
    10741 tcgttgagat attttgaagg aatcacagtg taagcaggcg ctttttcagg gaggcgcgtt
    10801 cttgcgggtt gcgtcccttg tgattggcga tgcgatccgc cgtggcggcc tggcgcttga
    10861 cgggccagta ggagcggcca tccttgccca tcgaccagac gctgctggcc tggttttcca
    10921 gcaggggcag atgggcgctc agggcttcgg gcgacgcgct ggtcagcgcc gtgcgctcac
    10981 gggtgcgcca gcgctgatgc cagagcttct tgtcctcgcg ctcgctgccg caggtcgtgt
    11041 gcccgacgat gggtgttttg cggcggctgc ggctcataac gtagtggtct ccaagaacat
    11101 tcaggactga tcccaggcgt cgatggtcaa gacctgatcg gcaggacagg cggctacgcg
    11161 gtcgggaact ggatggtgtt cagtctcatg ccgaccccat tcgattgatc gcgtcgcttg
    11221 cggcacgctg cgacgcaagg aggtttgcga cctggtttag cagccgtgtc cgctgcatgt
    11281 ctgttaccta tctccccgac cgctcattgg accaactcca gagattgggc tctatcgctc
    11341 agccaatacg aaaccggcat tggctgatgc cacaaccgag actaacacaa atggctcggt
    11401 acctgtattt cgcgccccgt gcacttggcc cggtcttgcc acggctatct caccttccct
    11461 gagggcacga acaatcccat tgccctgaaa gtaatcagcc attcccgaca aaacagtcca
    11521 cgtgtcttgg ccgtgaggat gaatgtgagc cgcaatttcc tgcccgggat ggacatgcca
    11581 aaccacgata attgagtctc gggtttcaag cacaacggaa cgaataggct cgccttcgga
    11641 cggctgaaca tactcggcta cagaaaatat tctcgattca acagtcatcg gagatccctc
    11701 tttcacagtt gtcgttacgg tcttcatcgt cggcatcctg acgcacggcg ggcaattgct
    11761 ggagcaacgc cggcagccat tcctgtaccg tctcccacac cacatcgagg ttgatgtcga
    11821 aatagccgtg agccatgcga ttacgcatat tgcgcatgct gcgccacggc acgtcggcat
    11881 gcgcctgggt gaactcgacg tagccatcca tcacctttgt ggccgcctcg ccgatgacga
    11941 tcaggctcat gatgacggcc tgctgggtgc gcttgtcggc caagaagtcg tccttggcca
    12001 tcccttccac gaagctgcgc gcatcggttg cggcctgctg aatgtggtcg aggtaatcgg
    12061 gcaggcggtt ctcgctcata tcggttgcgc ctccgcgagc accttggccc ggaacttcgg
    12121 cggcaggtcg ccgggagtca gcagatcgac gtcaacgccg agcagcgatt tcagttcttc
    12181 ttccaaatcg cccaagtcca acaacgtggc accgggcagc gcatcgacca acaggtcgag
    12241 gtcgctgcca tcccggtcgg tgccatgcag caccgagccg aagacgcgcg ggttcgcggc
    12301 gcgaaagcgg cctaccgctt cacgcactgc gcttcgcttc atgtcaagca caacagacgg
    12361 tcgcatgcgc atcctttctt atcgaaactc gttgagatga tatgcaatca agaatagaat
    12421 ttcaagaaga aggaaaccgc atgccccgcc gttcgatcct ctccgccgcc gagcgcgaaa
    12481 gcctgctggc gttgccggac accaaggatg agttgatccg tcactacacg ttcagcgaaa
    12541 gcgacctctc catcatccgg cagcggcgcg gcccggccaa tcggctgggc ttcgcggtgc
    12601 agctctgcta cctgcgcttt cccggcgtca tccttggcgc tgatgagcca ccgttcccgc
    12661 cattgctgag actggtcgcc aaccagctca aggtcggcat cgaaagctgg gacgagtacg
    12721 ggcagcgtga gcagacccga cgcgagcacc tggtcgagct gcaaacggtg ttcggcttcc
    12781 agccgttcac gattggccac taccggcagg ctgtccagtt gctgaccgag ctggccatgc
    12841 aaaccgacaa gggcatcgtg ctggccagag ccttgatcga gcacctgcgg cggcagtcgg
    12901 tcattgtgcc cgccctcaac gccgtcgagc gggcgagcgc cgaagcgatt acccgcgcca
    12961 accggcgtct ctacgacgcc ttggctgagc cgctgacgga cgtgcatcgc cgtcgcctcg
    13021 acgatctgct caagcgccgc gacaacggca agacgacgtg gctggcctgg ctgcggcaat
    13081 ccccggtcaa accgaactcg cggcacatgc tggaacacat cgaacgcctc aaggcgtggc
    13141 aggcgctcga cctgccctcc ggcatcgagc ggctggttca ccagaaccgg ctgctcaaga
    13201 tcgcccgcga gggcggccag atgacgcccg ccgacctggc gaagttcgag ccgcagcggc
    13261 gttacgcgac cctggtggcg ctcgccatcg agggcatggc caccgtcacc gacgaaatca
    13321 tcgacctgca tgaccgcatc ctgggcaagc tgttcaatgc cgccaagaac aagcatcagc
    13381 agcagttcca ggcatccggc aaggcgatca atgccaaggt gcggctgttc gggcgcatcg
    13441 gccaggcgct gatcgaggcc aagcaagcgg gccgcgatcc gttcgccgcc atcgaggccg
    13501 tcatgtcctg ggatgctttc gccgagagcg tcaccgaagc gcagcggctc gcgcaacccg
    13561 aggacttcga tttcctgcac cgcatcggcg agagctacgc cacgctgcgc cgctacgcgc
    13621 cggaatttct cgacgtgctc aagttgcggg ccgcgcccgc cgccaaggac gtactcgacg
    13681 ccatcgaggt gctgcgcagc atgaacagcg acaacgcccg caaggtgccc accgacgcgc
    13741 cgaccgagtt catcaagccc aagccgcgct ggcagaagct ggtgatgacc gacaccggca
    13801 tcgaccggcg ctactacgaa ctgtgcgcgc tgtcggagct gaagaacgcg ctgcgctccg
    13861 gcgacatctg ggtgcaaggc tcgcgccagt tcaaggactt cgaggactac ctggtgccgc
    13921 ccgcgaaatt cgccagcctc aagcaggcca gcgaattgcc gctggccgtg gccaccgatt
    13981 gcgaccagta cctgcatgac cggctgacgc tgctggaaac gcagctcgcc accgtcaacc
    14041 gcatggcgct ggccaacgag ctgccggacg ccatcatcac ggagtcgggc ctgaagatca
    14101 cgccgctcga tgcggcggtg cccgataccg cacaggccct gatcgaccag acggcgatga
    14161 tcctaccgca cgtcaagatc accgaattgc tgctggaggt agacgaatgg acgggcttca
    14221 cccggcactt cgcccacctg aagtcaggcg acctggccaa ggacaaaaac ctgttgctga
    14281 ccacgatcct cgccgacgcg atcaacctgg gcctgaccaa gatggcggaa tcgtgccccg
    14341 gcacgaccta cgccaagctg gcctggctgc aagcctggca catccgcgac gaaacctacg
    14401 gggcggcact ggccgagctg gtcaacgcgc agttccgaca tcccttcgcc gagcattggg
    14461 gcgacggcac cacgtcatcg tcggacggcc agaacttccg caccggcagc aaggccgaga
    14521 gcaccggcca catcaatccg aaatacggca gcagcccagg gcggacgttc tacacccata
    14581 tctccgacca gtacgcgccg ttccacacca aggtcgtgaa cgtcggcgtg cgcgactcga
    14641 cctacgtgct cgacggcctg ctgtatcacg aatccgacct gcggatcgag gagcactaca
    14701 ccgacacggc agggttcacg gaccacgtct tcgcgttgat gcacctgctg ggcttccgct
    14761 tcgccccgcg cattcgtgac ctgggcgaca ccaagctcta catcccgaag ggcgatgcca
    14821 cctacgaggc gttgaaaccg atgatcggcg gcacgctcaa catcaagcac gtccgcgccc
    14881 attgggatga aatcctgcgg atggccacct cgatcaagca gggcacggcg acggcctcgc
    14941 tgatgctcag gaagcttggc agctacccgc gccagaacgg cctggccgtc gccctgcgtg
    15001 agctgggacg catcgagcgc acactgttca tcctggactg gctgcaaagc gtcgagctgc
    15061 gccgccgcgt gcatgccggg ctgaacaaag gcgaggcgcg caacgcgctg gcccgcgccg
    15121 tgttcttcaa ccgcctgggg gaaatccgcg accgcagctt cgagcagcag cgctaccggg
    15181 ccagcggcct caacctggtg acggcggcca tcgtgctatg gaacacggtc tatctggagc
    15241 gggccgcgaa cgccttgcgt ggccacggtc aagccgtcga tgacggcctg ttgcagtacc
    15301 tgtcgccgct cggctgggag cacatcaacc tgaccggcga ttacctctgg cgcagcagcg
    15361 ccaagatcgg cgcgggcaag ttcaggccgc tacggccgct gcaaccggct tagcgtgctt
    15421 tatttaatga gatggtcact ccctccttcc cggtactatg ctgaggatag gctttcattc
    15481 ggagaactat catggaaaac attgcgctca ttggtatcga tctgggtaaa aactctttcc
    15541 atattcattg ccaagatcgt cgcggcaagg ctgtttaccg taaaaaattt acacggccaa
    15601 agttaatcga atttttggcg acatgccccg ctacaaccat cgcaatggaa gcctgtggtg
    15661 gctctcactt tatggcacgc aagttggaag agttggggca ttttcctaag ctgatatcac
    15721 cacaatttgt ccgtccattc gttaaaagta acaaaaacga ctttgtcgac gccgaagcta
    15781 tttgtgaagc tgcatcgcgt ccgtctatgc gttttgtaca gcccagaact gaatctcagc
    15841 aggcaatgcg tgcgctgcat cgtgtccgtg aatccctggt tcaggataag gtaaaaacaa
    15901 ccaatcagat gcatgctttt ctgctggaat ttggcatcag cgttccacga ggagctgccg
    15961 ttattagccg actgagtacc cttcttgagg acaatagttt gcctctatac ctcagccagt
    16021 tattgctgaa attacaacag cattatcact atcttgttga gcagattaaa gatttggaat
    16081 cccagttgaa acgaaagttg gacgaagatg agattggaca gcgcttgctg agcattccct
    16141 gcgtcggaac actgacagcg agtactattt caactgagat tggcgacggg aagcagtacg
    16201 ccagcagtcg tgactttgcg gcggcaacag ggctggtacc ccgacagtac agcacgggag
    16261 gtcggacgac attgctggga attagtaagc gaggtaacaa aaagatccga actttgttgg
    16321 ttcaatgtgc cagggtattc atacaaaaac tggaacacca gtctggcaaa ttggccgatt
    16381 gggtcaggga tctactgtgt aggaaaagca actttgtcgt cacttgtgct ctggcaaaca
    16441 agctggccag aatagcctgg gccctaacgg cacgacagca aacttatgta gcataacggc
    16501 agaaatacac cggtttaaag aatcactgat ctggttttgc gaatactgat attgatgata
    16561 ctaacggccc accggcctgt tgaggaacct gtaaaacgga aaggctcatt gaagccgtat
    16621 attttctgga ggttcatcag gcgcggaact catcgaggcg cgggaataaa atcccattca
    16681 gacgccggat agattcaagc aagccaattt atcgtcaaaa tcggtgttgc aaaaacggga
    16741 gtgaccatag attccgtttt ctgagacgac cccaaaaggg attactttga cttcttcatt
    16801 gctgttagcg ggttaaggct aatcagggca gggggtaggg tggcagaatt tatagcccgg
    16861 caaccggcta cgccgggctt tcggcgccat ttgactccac agacacatgt aacctcatct
    16921 ggcgcctcca tgccgctgac gcggcatcag gaagtgtaga ctttaacgtc tgctttgtgc
    16981 caggagcgga agttgttaat tacagtttgc gtggatcacg ggtcagggtc actctactta
    17041 atactactcg tccccacctt cggtgatcag acctgacttt ttcagctcaa ccgccagctc
    17101 ctgtaagctc gggcgaattg ctttttccag acgggtcata ccatcaatca tccagctaat
    17161 gatgtcaggc caaagttctt tgtttccgcc gtcaaatgct tttgcacaaa caacctggca
    17221 gctttttctc tcaggcagta gtcgccaatt gagcatccca ccaaactgcg actcaatatg
    17281 cgttttgcgc tctgacagac gctcaaacag ccatgtattt tctaccgcat ctgaacgtga
    17341 aatattgagc tgaatgcgag catctttttg cgagaagatc acttcaaaag gcacgccact
    17401 aacccccgaa cccgctgcca gccaatggtc tgtcgtaggt gctcggttgt taaataatga
    17461 acatgtgctg gtacggaatt tttccagtgc taacgaccag aactcacggc gtaaataatg
    17521 tcgttgttgc agttcgctac tgcttgaggt ggactgctct tctgcctctt tctgcgccat
    17581 tccaatcatg taggattccg cttcaggagt cggaatgacc tgccgtatat cgacaaaaac
    17641 atcctcggca aagaggtacg gcgtcgcttt gaagcattgc actcggatgc caaactgcat
    17701 tagccatagt gcagtattgg taacttcttt gcggaaattc gccgctacca tgataacgcg
    17761 ctgtgtccct tttcgattga gcacaccttc tttcaaactt tcccagccca taaattctgc
    17821 aataacttct gccgcagggc ggatttccga gggttcatgt tgtgtaagat aaagctgaaa
    17881 aatttcgaca acgctttcct gacgaaggtt ggcgcagtaa cccgcatact tcagcgcctg
    17941 ccagaccacg tcacgccctg aatcatcaag tttattctcg ataatgacca agttgccttt
    18001 tttgtcgata gccagcagat cgagacgttc gttagtctca tcaaaaccag caaactcttt
    18061 ctgaataatt aaaagttcgt cctctttatc atctttctta gtcaacgctt gaggattgtt
    18121 tgccagccac tcttgcaaat gatcgcgttc gcgaaaacca agactgctaa aagagacttc
    18181 catgagcgac ttgaggctat tgttttgccg atcaatctta tacattttct atctcacatc
    18241 ctgattgttt tgcttctggc agaattatct tatttgggtt tgagggtaat ggaacggaaa
    18301 cgtacgctaa gaagataatt gtttgtttat attgaaattt aaatttctca attccccatt
    18361 tatcatatcc tccggtagcg tgagctgaca agctccctgt tgactcacac ctaatgctgc
    18421 tagcaatgtc cgtagatcgc tcatagcgga ctgcgctcac ttactgctgt gagcgttaca
    18481 ttgagtttaa tgccagccag gtatagtcag gttgacagta cttgtttcag accttcgtca
    18541 ttaaaaacgg ttccggtctt caggacgcca taacaccagt gcaccagttt ccgcatcagc
    18601 gcgccaatgg ccaccatttt aggtttaccc cgcaggcaca tctcatcgta ggtaatgact
    18661 ccaaattatt gatagtgttt tatgttcaga taatgcccga tgactttgtc atgcaactcc
    18721 accgattttg agaacgacag cgacttccgt cccagccttg ccagatgctg cctcagattc
    18781 aggttatgcc gctcatttcg ctgcgtatat cgcttgctga taacgtgcag ttttcccttc
    18841 aggcgggatt catacagtgg ccagccatcc gtcatccata tcacccaaag ggtgacagca
    18901 ggctcataag acgctccagc gtcgctatag tgcgttcacc aaatacgtgc gcaacaaccg
    18961 tcttccggag cctgtcatac gcgtaaaaca gccagcgctg ccgcgattta gccccgacgt
    19021 agccccactg ttcgtccatt tccgcgcaga cgatgacgtc actgcccggc tgtatgcgcg
    19081 agaataccga ctacggcctg agttttttaa gtgccgtaaa atcgtgttga agccaacgcc
    19141 cataatgcgt gcactggcgc gacatccgac gccattcatg gccatatcaa tgattttctg
    19201 gtgcgtaccg ggttgagagg cggtgtaagt aaactgtagc tgccatgttt tacggcagtg
    19261 agagcagaga tagcgctgat gttcggcagt gcttttgccg ttcgcaccac ctcgtcagta
    19321 gctgaacagg agggacagct gataaaaaca gaagccactg gagcacctca aaaacaccat
    19381 catacgctta atcagtaagt tggcagcatc accgaaactg cctacctgat tcgtttagct
    19441 acgttcgtat atgagtcaga gaatgaaatt taaacaggat gcatcacttg ttgaaacatg
    19501 taagataaat cttatctacg atatttaagg aaaggcacag cgtggcgact tatcgggctt
    19561 actacgggca ggacagagat cgtgaatact ttgaacgcat atttcagtca gcaaacatca
    19621 atttcatcat tggctcagga gcatcactgc ctgcaatcag cgtgttaggt gatattgaaa
    19681 gcgagcttga ggctctggtc cgcgccggaa atgatgatga atacttcagt aaatctgagt
    19741 cttttctgga caatgtatgg aaggcaaaca acgtcctcct gaagcgaagc aggcccgcag
    19801 aggtaatcct tcctacttta atagatgatg tcgtatcgac acaaaacaac tacgcgaagc
    19861 tcatgcgggc attagaaatg cttctaacga ggcggcggac tggattgcta ccgcggcgca
    19921 tcaacctttt tacgactaac tatgatttgt tcattgagga tgcggcggtt aaaaataaca
    19981 acgtcattct gaatgatgga ttccgtcagc gcgctgatat ttacaaccgg acagtattcg
    20041 atgccaaatg tttttatcag accatacacg caaccggaaa cctttataat tacagcgtgg
    20101 aactacctac ggtgaatctc atcaagctgc atggttccct ttcctggcat agctatgata
    20161 aggaaatcta ttattccatt aaggatatga agccagttgc gttcaataca ccaaaggaga
    20221 agcagggctg ggttatgtca catcaactgg ttctgccgcg aaaggataaa tttcgtgaaa
    20281 ccttacttga aaacgtgtat tacgatctac tacggactta ttcaaatgag ctggataaag
    20341 aaggctcttt gcttatagtt ttcggatttt cttttgcgga tgagcatatt gaaaccctta
    20401 ccaaaaaagc gctacgaaac gccacgctca aaattgttat attcgcttac aacgaggcgg
    20461 ctaaagacct atttcttggt aaattccgag attattccaa cgttgatgtg gtttttactc
    20521 ctggagctcc gttggacttc aaaaagatga atgaaattat aaccagcttt cttggaggta
    20581 tgaaatgacc tccgcttttg ttaacgaaga agcagtatta aggatcggtg aggttcgtga
    20641 agtatcgggc agaacactca gcgtgcttgt cgataaaaat aaaaatctga gtgacctttt
    20701 ctatcacggt aaggtgctca aaaatgtttc agtaggtagt ttcatcgaag tcaaaaaagg
    20761 cttcatgagt ctgattgcaa aggtagaaac cgagaagatt gtcgaggaaa aatcacctgt
    20821 tggtagcgga agcgattcgc ttcgcttccg acgctatctt acagcctcac tggcaggcta
    20881 cattgaccgg aacgggcgct ttactggcgg aacacgcgag ttacccctta tcggcaatga
    20941 agtttttctg atgtctgagg aacaacttca tcttatccac tcgatcgcgc cagcgggcga
    21001 gtctgggctg aatttttcgc gcaccgatct cgaagatatt gatatcactc tcccgataag
    21061 cggccttctc aactcacaca tcgccatctt cggtaatact ggcagcggca agtccaatac
    21121 tctggccgcg ctttaccagc atggctatga ggccctgaaa aacctactag gcgaaggatt
    21181 cagaagtcgg tcacggtttc ttttatttga tttcaatggt gaatatggtg ggagaagttg
    21241 cattacgcgc gacaaggttg tttacaatct tagcacgcat gatgaagagg gtgatcgcat
    21301 tccgatgcct gctgagatac tgcttgagca tgagattctc tctgtcctga cggatgccac
    21361 cgacaaaacg cagaaacctt tcctgaagcg agtacttgaa ttcaaaaagc gagtggagtc
    21421 gaagctgaac cctcagtcat attttcgtga aattctgaaa cggcgggtca ccgaaactct
    21481 gtttggttgc gaaaagaaaa aaagtgacga cctgattgat ttattccgtc ccgtacttaa
    21541 ggacgaagac ctgatagcag atattgaatt tttttataac aacggcggcg tatggcgaac
    21601 taagacaggt gtttactttt ctaatgaaga aaatactcat cagtgcaata tgtaccagag
    21661 ggctcagaat tatgaatttc ccgaagatat aatggaagag ttgctggact atatgtatgt
    21721 tcagctaatt attgaatatc tttcaagtcg ctcaaatcct gaacatcttt ctcctgtcat
    21781 caaccgaatg agcggactga aaaaagatat tcgtaaaatt ttcaatactg catccggcgg
    21841 aaccatctgg gcagaaacga actttgttgt cctgaacctt aatatggtca atctgaccat
    21901 gaaaaaaacg ctaccacttt taatggccaa atgggcctat tcagcaaaaa aaatggataa
    21961 ggtaccgtcc actctccatc tcatcataga cgaagcacac aatatccttt cgaacacctc
    22021 gttcagggaa tcagaaagct ggaaggatta tcggctcgaa acgtttgaag agataattaa
    22081 ggagggcaga aaatttggcg tctttgtgac gatatccagt cagcgaccaa atgatatctc
    22141 cccgactatc atttctcagg cacataacta tttcattcac cggttgataa atcagaacga
    22201 tctgtatgct attgaaaaat ccgtttccta catagaccgc atgactgaag aatctattcc
    22261 aacgcttgca accggcacct gcatattcag tggcgtgatc tgccctatgc cacttaagct
    22321 tcgtataaac gagctgtctt tccgcaaaaa gccgcacagc catacgctga attttgaaga
    22381 cctaatgctt tagccacggc tgccacttct ctgagcagaa cggcagcctg tctccccgtt
    22441 cagtgtgagc agatcagcta atgctggaat cgcgtccggc tcggtcacct tcataaacgc
    22501 cgcctcaaac taaagattct tcttgtagta ctagcagtaa ttacaaaaag tgcttttatg
    22561 ctttttaagc attgctttta tatttttaat aatgtcagtt tttatccctc actcctttct
    22621 tttcctgaga tccgaaaact ccaagttccg gatctgattc agccccgccg gcgcgcagcg
    22681 gcccggaaac acaagatgta gcggtgtttc cagctgtcag tgaccatata tgttgtgccc
    22741 ctcccctgcc ccgtgaccgg ccgctcacca ccctgaaagg gcgctgtggt tattccgtgt
    22801 gcgtggtaca cttccggaaa ctgtggaata acataaaagt cggatccggc cagagcggcc
    22861 gtcaggtaat ttaattacgt tgttatatgg ctgcttatta ttttagtatg tgaaaatcac
    22921 tctcgtgaaa gtcactgtcg cgacagagtg gcactcatct gacgatgatt gaggtgtggt
    22981 aaaattgcac ggctaactat tcaactgagg aaaggacatg tttactgcat tcaatgagag
    23041 aaatgatttc agttatgctt ttgaaaaaat ccgtaatgcg atttccgcgc caggagaaaa
    23101 taatctttat gctgcaacag aattaggtct tggcattctg ctccgtaaat acgagcagtt
    23161 tcgccaggaa ctggatgcgg ccggtgagct gggaaactgg gaatatgatc tcgataccta
    23221 caatcactgt attgcggtgc tgcaacgtta cttcaccggc aatccatccg gactgacaga
    23281 acgtgatgcc cggatttaca gccattacct gcagactgag cacaaaaggt ttgtgaaact
    23341 ggctgaagag ctggctgccg gccgctgact acggacagag ggcgggattt ctcaggaata
    23401 taaaggggta aatgatcaat gactgatata caggccgcaa ctgagagtat agttgctgcg
    23461 acatcccatc cggtttccgt acagctgatt aatcaagggg cggggatctg gggaaacgtg
    23521 gcaaccgggc ttatcactgg cctgcttact gggggtataa cactcactgg catctggctg
    23581 acacattatt tcacgcttaa gcgtgagaga caggcgtcag aagataaaat gaaaaaggaa
    23641 ctgcattaca ttgccaccga gttggtattc atgcttgaac ggtatgctga gggttgtttc
    23701 cgggttgtga cggatgacgg ccaggatgat gatgcccccc agcctgagag aaaagctgtc
    23761 acgaattacc ctgaactgaa tctgatcgat gtctccggtg actggcggac tttagagcca
    23821 cgtcttatgt atcgcatccg tgaactgccg gtgctccagg atgaggccca cagggcaatt
    23881 gcatatgccg ccgaatactc cgaccctcct tggcataagg actatttcag ggaacggcag
    23941 tatcagttca cgcgcttggg catcaacgct gtcattcttg ccgtccgtct gcgcaaggca
    24001 accgggatgc ccgaaacacg tcttacaggt catgatgaat ggtctgcagt ttccgtgttt
    24061 cgtaaagtct ggaggcgcga aagagccctg cgcgctgctg aagctacccg caacagggag
    24121 tggaatcaat tagtgatacc tgatggaatg tcaaaccaat gagcggcctc ttatcatatt
    24181 ctcacccgca gcagccggcg caaatgccgg tggccattga ctatcccgcc gcgctggccc
    24241 tgcgccagat ggcgctcgtt caagatgaac taccgaaata cctgctggca ccggaagtca
    24301 gcgccctgct ccattatgtg cccgatttgc accgcaagat gctgctggca accctctgga
    24361 acaccggcgc acgtatcaac gaggcgctgg cgctgacccg gggggatttt tcgctggtgc
    24421 caccgtatcc gttcgtgcag ctggccacgc ttaagcagcg caccgaaaaa gcggccagga
    24481 cagccggccg agctcccgcc ggtagccagg ctcatcgtct ggttccgctt tccgatcacc
    24541 actacgtcag ccagctgcag atgatggtgg ccaccctgaa aattccgctg gaaagacgca
    24601 acaagcgtac cggcagaaca gagaaagccc gcatctggga catcaccgac cggacagtac
    24661 ggacctggat tggcgaagcg gttgaagcgg ccgccgtcga cggggtgaca ttctcggtgc
    24721 cggtcacccc gcatacgttc cgccactcct acgcgatgca tatgctgtat gccggcatac
    24781 cactgaaggt tttgcagagc ctgatgggcc acaaatcgat tagctcgacg gaagtctata
    24841 cgaaggtgtt cgcacttgat gttgctgcgc ggcatcgagt tcagtttcag atgcccgaag
    24901 cggatgcggt agccatgctg aaagggaata tttaagtact taggagaatg atgctggcga
    24961 acgtcctgct cgccggggag gtctgtcaga cgttatctgg accagctgac gggaatatct
    25021 gctctgtatt cctcatactg ctcatagatc gcatgctgaa gcatcgtaat acgttctgac
    25081 aacctgttgg cgtccgacat atgccgccat tccccctcaa tagtggtttt ctgtccatcc
    25141 gggagattga gcgtgatcaa tacctttgta tcacgaataa tcaccccgtc agtgaaagaa
    25201 ttaagaccac tccttacggt attatctatc tgtatagttt caagtttcat cttgttacct
    25261 cctgttgacc ggatcccaag catagatatc tgaattcaaa ttgcctagtg aaatgtctgg
    25321 atatgccgca tttttcccct tatacagcga agctggccaa aggccagccc gcttggattt
    25381 atcgcttttg ccagtagatc agcatggcaa ggaacaggat tgttgccccc tgagaagcgg
    25441 tcaggaaagt ttccagcaat gacattatcg taaaactccg cattattcag gtgtgtgatt
    25501 caggggcctt agtccccctt ttacaggacg tagtgttctg tcacgacgga agccagggtt
    25561 aataaaaacg attcgaatat gtctgcaggg acgatagaaa tcttcgtgcg ggttgtctcg
    25621 ctgtagccgg ctctggagag cgactcgggg gaggagtagt atcttccggc cacggatatg
    25681 atcgagccag cagtgctcgc cgcagtcgag cgacagggcg aagccccgag tgagcgagga
    25741 agcaccaggg aacaaaactt ataaattctg cttacgctca atgcctgaaa aatcacctcc
    25801 cctcggggtt atccacttat ccacgggcat atttttataa agtacttttt tattcttttt
    25861 ctttatttta catcttttag ggagcctgaa agccgcgtac agtgcggcct gagagggggc
    25921 ctgtatgggc aactggtaaa cataatatgg gaaattaatc acgtatcagt gggttttgtg
    25981 tcaacaagct atgggatacg catcaacaag ctatgggaaa gaggtcaagt tcagttctca
    26041 attatccact tgtggataaa gtgcagattt ttccggtgga taagtatcgc gatagcttgc
    26101 aatttctgtt ttcactgtca ttatgggtgg gtaaaaattt acccataggc attgaaatgg
    26161 atactcaagc actcttgcca gctactaaaa cgtttaaaaa acgcgccagt ataaagcaat
    26221 ctaacgaatt gaccgaagct gcatattacc tgcctcttca ggcaaaacgt gtgctgtggt
    26281 tatgcctcat gcaggcctat tttaatgaca gccaggaaga tgactctgac gtattgccgc
    26341 tcttcaaaat cagcgtttcc gattacgtca aatacttcaa tgtcgctacg tctgtcgcca
    26401 gtcgtgatgt gaaggctggg gtaaatgctc tgggcgaatc aacggttacc ttttatccaa
    26461 aagaaggtga gtttgaagaa gttaaacgtc cgtggctggc tgaagcagga atgaagcgag
    26521 gccggggttc ctggcagatt gaatttaact acaaggtcat gccattcctg gtcggcttaa
    26581 cctcccagtt cactacctat tctctctatg actgtggcca gcttaatagt gttcgtgtca
    26641 tccggcttta tgaaagcctg tgtcagttcc ggagcactgg tgtctggatc accacacatg
    26701 actggttatg tgaaaggttt atgctccctg cctcgcagaa aaacaatatt gctgaaatga
    26761 agcgtacctt cctggaacct gctctgaaga aaattaatga gaagacgcca ttaaaggtaa
    26821 catataccac tgaagaagat ggtcgcttgc tgtttaattt tcttgataaa aaacaatagt
    26881 ctgtaatttt tatttcctcc ccccttagtt tgttgctgac atatgggggg atactgaact
    26941 tgctgtgttt cccatagtgc ttgcctaact tgacctgttt cccacactcc cgaccgtccg
    27001 agaagttgac ctgtttccca tagtccgggc cgtccgagaa gctgacctgt ttcccttagt
    27061 ccgggccgtc cgcgaagttg acctgttccc cacactcccg gccgcccgcg aagttgacct
    27121 gtttcccaca gtccgggccg tctgcaaagt tgacctgttt cccacagtcc cggccgcccg
    27181 cgaagttgac ctgtttccca taatccgggc cgtccgcgaa gttgacctgt tccccacact
    27241 cccggccgcc cgtgaagttg acctgtttcc catagtccgg gccgtccgcg aagttgacct
    27301 gtttcccata gtccggagcg tccattaaag ttgacctgtt tcccacagag gatggaaaac
    27361 tcttcttgtg ctgagcgtaa gagctatctg ccggaacggt tcctcttcgc ttcctcgcca
    27421 gttcgctcgc tacgctcggt tacatggctg cggcgagcgc tgatacataa ggctcagcat
    27481 tgcactggtc gtaactaaaa tcagaatcct tctgaatgac tctcctgtct tgcaagttga
    27541 atacctttct caaagccctt ttgtatgagt tgctgttgat ggtcaaaagt gcgtctgcgt
    27601 gttgctgcag tgtgatttag tagcacgccc gtcgagcttc atcccccttc tgttgagagc
    27661 gaaatcaaaa caatatgatt tttttcttgc aacatgacac tttttgttca aaatgacaaa
    27721 aaacgtcatg aggtgataaa tggacaatat tgagcagtta cggaaagtcg ctacacgtgc
    27781 aggtaagctt ctgacatctt tgagcgaaag tatccgacag caaaaagagg aattgaagct
    27841 taccgagttc tatcaggaat acagcaaagc cgctctgtat aagctgccta agctcagtaa
    27901 aggcagtgtt gagtatgctg tgtccgaaat ggaagccggt ggctacattt ttaaaaagaa
    27961 accttctggt aatacgatga aatacgcgat gacgattcag aatgtcatcg atctgtataa
    28021 ccatcgtaaa gtaccgaagt acagggatcg cttcgataaa gcctttacga tttttgtatg
    28081 taatcttaaa ggtggtggtt ccaagacagt ttctaccgct tcattatcac atgcttttcg
    28141 agctcatcct cagcttctgt tcgaagacct gcgtattctg gccatcgatt tcgatccgca
    28201 ggcatctctg acaatgttcc tgagccatga gaattcagtg ggcttggttg aaaatacggc
    28261 tgctcaggcc atgctccaga acgtgtctcg tgaagaatta ctttccgatt ttatagtacc
    28321 gtctattatc cctggtgttg atgtaatccc cgcttccatt gacgatgcat ttcttgctga
    28381 aggctggaag ggattgtgtg aagaacatct gccagggaaa aatattcatg cggtgcttaa
    28441 agagaacatt atcgacaagc tccagcatga ctacgacttt attttccttg atagtggtcc
    28501 tcaccttgat gcgttcctga aaaactgcat tggggcggca gacctgatgt tgacccctct
    28561 tccaccggcg acggttgatt ttcattcttc cctgaagttt gtggccagcc tccctgccct
    28621 catagattcc atcgaaatgg atgggcacac ctgcaatctc atcggtaatg tcggcttcat
    28681 gtccaagatc ctgaacaagt ctgatcacaa aatttgccat agtcaggcca aagaggtttt
    28741 cggtgccgat atgctagaca tggttctgcc aagactggat ggtttcgaac gttgtgggga
    28801 gacttttgac acagttattt cagcaaatcc agcaacctat gatggaagta cagaggcact
    28861 aaaaagcgca aaatcagcag cggaagactt tgcgaaggca gtctttgatc gcatcgagtt
    28921 cattcgtact aacggaggta tgtgatgtcg aatgagaaaa gaaaaaccat cggcagacag
    28981 ttaaataccc aggcgtcaat tgcggaaatg acggacaccg gtagaagcca ggtatttacc
    29041 ttaaaaaccg gcaggaaggt aacgttcagg tttgttcggg tgcctgcatc tgaagttgaa
    29101 agtaagacct tcgtaaacca ggaaaacaac ggaagagatc aacttgcact gaccagggaa
    29161 tccctgaaat ccattatcca gacgattaag tttcagcagt tctttccctg tattggtatt
    29221 aagcaaagtg aaaggattga gatactggat ggttcaagac ggcgagcctc agcaattttt
    29281 gtccgtacag gccttgatgt aatggttacc gaagagcatt tatcagctga tgaagctcgc
    29341 caactggcta aagatatcca gacagctaaa gaacataatc ttcgggagat tggcctgaga
    29401 ttgatcgctc ttaaagagtc cggatttaat caaaaggaaa ttgctgaact ggaggggtta
    29461 tctcaagcta aagttaccag ggcgctgcag gcggcggccg taccgcaaga cttgatttct
    29521 ctgttcccgg ttcagtcgga gctatcgttt agtgactata aacttctttt agaagttaat
    29581 gaaaaactca gtgaaaaggg attaacgcct gaagaactca ttcagtctgt atcagctcag
    29641 ctcgatgcaa ttttgagtga aggcgagcga ccagaagacg aacagaaagc cagtatactg
    29701 aagctgattt ctcaggcatc tcaggcattg atagatccat ctcccaagga aaagtcagtg
    29761 gtttccccac tctggtcttt tgaagaaaag gacaagttcg cgcgtaagcg tgtgaaaggg
    29821 cgtacgctga cttatgagtt tagccgtatg tcaaaagtga ttcaggatga actggacaag
    29881 gctatcaacg aggtccttga cagaaatttg agtcaataat ttcgccatgg cgatttcaca
    29941 tctaacttat tgtaattagg cagtttaggc tgagaatttc aaggtgaaat cgccaaagtt
    30001 ttacgccagt ttcgctgaag gaatatctga ccatcgtgtc gtataagcag gagaaagcat
    30061 ctcccgtttc atctgccatt ccggggcaat accccgcccc gcaaaccata ctttacccag
    30121 ccctgagttg ttgatcccgt ccagaacctt catcagctca gcactgtaag ggcgtggcgg
    30181 gcgttcgtcg aacagctgca gctgcgaaac gccggagccg gtgaagtcat tcagcataac
    30241 tccggctttg gcataccggt gcccatccct ccagatacgc tccagagccg ttgtagcggc
    30301 tgcaatgatg tccctggtgt cctgagtggg tgtaagaagt ttttccgtag ccacgttgcc
    30361 gtagtaaggc tctttaatgg cgaacggaga cgttttgatg aaaacggaaa tatgccggca
    30421 atactggtgc tctttacgca gtttttcaga ggcccgctct gcgtgctgac agatagcctg
    30481 acggagtgac tcgtactccg tgatcttcac gccaaaactg cggctgcaga caatttgctg
    30541 tttcgtcgga ggggcttcct caagcgaaag gcagctttcc ccgttcagtt cccgtaccgt
    30601 tcgctcaagg accacagaaa aatttttgcg gatgaaggcc gggttcgtca gggcgagatc
    30661 gagcgcggtc ttaatgccca gtacattcag cttgcgtgca atacggttac ccacccccca
    30721 gatttcttca accggctgca gtgaaagcag tttccgcgtt ctctgcggat ttcccctggt
    30781 cagagcaagt acgccacgaa actgtttcca ctcttttgag gcccactggg ctgattttgc
    30841 gagggtcttc gttggtccgg cgcccacgcc aatggtcagg tgggtacagt catacacgtg
    30901 ctgacgcagc tgccggccga agtcctcaag ctccatacag tgctccacgc cggtcaaatc
    30961 gaggaacatc tcatcaattg aatactgttc cactctgggg gccagttcct ccaggctgtt
    31021 catcacgcgc gccaacatcg aggcataaag ttcatagtta cttgaaaacg catatatttt
    31081 ttccgggtat ctttcgtttt ttatctgaaa ccacggagtt tccattttga tccagggctt
    31141 cgcctcggca ctgcgagcga ttacattccc gtcgttgttg ctcaggacga ctatcggctt
    31201 tcctttcaaa tccgggcgga aaacacgttc acagctggca tagaagctgt tcacatcggc
    31261 cagggcaaac atcagtacat ctccctcggg cggtggatga tatgcgtgac gacgccaaag
    31321 atatccagct cgtcgggatc aggataaatc ggcgaccagg aggcattcat gggctgcagc
    31381 gtcagtcgcg gcgtcagcag aagccgtttc accgtaaact ccccctgcat gctggcgaca
    31441 acgatatcgc cgtgccgcgg cttttcagca ctgtccacaa ccagcagatc gccattgtac
    31501 agactgccgt cggccatgct gtctccgctg gcacgcaggt agtacgtcgc gctcggatgc
    31561 cgtatgcagt aatcatggag atccagatcg gactcgacat agtcagcagc agggctggga
    31621 aaaccgcagc tggccagatc ggcaaacaat ggatgggcct gtggcgggag ttctttcccg
    31681 gtgctgaaaa gttgtagttt catctttcct cctgacactc taattttact ggttatacat
    31741 acagtgttca ccgggagacc ggtagagatc aaggggtgaa agtccccgac cattgaagga
    31801 ccagcaatcc acaaggtccc cgagtcatgc gttgcatacc gcgaggtatg gggcgaagcg
    31861 ttgacagggg tgttgacagg ccagccattg agccacgaaa tgtatattaa attaccgggt
    31921 gccgacgttg tactgttaac ggaaggcaac atcatagggt gcgatactgc gagtgccaca
    31981 tggacccggc ggggtctgag accctggcat gtcaatacga tctctacgcg ggaaccggga
    32041 gatctcccct ctgaccatct gccagtgtcg gagacggccc gcaccgggaa gacgaggagt
    32101 catagccggt gatgtacgga gaggagaagt cggactcgct catagtagcg gcgaagcagg
    32161 cgaacaaccc gaaaggagcg gagtcagtgg agcgaaggag cggggccaag gggaacgcgg
    32221 aacagccaca catgcgccgg acacagagcc gggaaagcat gtcacagagg ctgtcacgcg
    32281 tgcgggaagc tgcgaagcag cggaagaaag aacggtttac agcattgttc cacctgctga
    32341 cagtcgaagc actggaagcc gcattcctct ccctgagcag gaaagcggcc gccggagtgg
    32401 atggcatcag gtggatggac tacgccggaa acatgaagaa caacataaca gatctgcacc
    32461 ggaggctaca tcagggcagc tacagggcgc agcccggcag gcgtcactac atcccaaaag
    32521 cggatggaaa acaacgcccg ctcggcatcg cctcgctgga ggacaagatc gtccagtatg
    32581 cgctggtgaa aatcctgaac gcagtctatg aaaacgactt tatggggttc tcatacgggt
    32641 tcagacccgg gcgaagccag cacgatgcac tggacgcact ggccacaggg ctggtacgca
    32701 ctaacgtaaa ctgggtactg gatgccgaca tcagtcagtt cttcgacagg gtgagccacg
    32761 aatggctgat caggttcaca gagcatcgga tcggcgaccg gagcgtaatc aggctcatac
    32821 gtaagtggct cacagccggg acgttggagg agggtcaatg gcgagcaacg gaggaaggca
    32881 ccccacaggg tgcggtcatc tcaccgctgc tggcaaacat atacctccac tacgtcttcg
    32941 atctgtgggc gcatcagtgg cgacgtcgct atgccacagg caatgtggta atggtcagat
    33001 acgccgatga catcgtcatc gggttcgaca aacgatacga tgcccggcgc ttccgtatag
    33061 ccatgcagcg cagactgagg gagttcggac tcacggttca cccggagaaa acccgtctga
    33121 tggagttcgg ccgcttcgct gccgaaaacc gtgccatcag gggaaaaggc aaaccagaaa
    33181 cgttcaactt cctcgggttc acgcacatca gcgggaaaga tcgcaacggc aggttcatgc
    33241 tgatacgaaa gacccgccgg gatcggatga cggcaactct gaaagccatc aaagacggtc
    33301 tgcgaaggcg ctggcattac tcaatccccg aacagggaaa atggctcagg agagtggttc
    33361 agggatacct gaactatcac tcggtaccgg gcaacttccc caccatgcag aagttcagga
    33421 cacacgtaac aaacctctgg cgccgggcgc tcaggcgcag gagccagaag gatgatacga
    33481 cctggacgaa agcaaacaaa ctggcagccg catggctacc aagggttcgg gttcttcatc
    33541 catggcctgt ggagcggttc accgccagac acccgaggca ggagcccggt gcgtaaatcg
    33601 cgcacgccgg gatctgtgcg gggggtatcc ggtaacgggt atccctaccg cgacatattt
    33661 aacagcgtga cgataatcca gatcgcctgc cggataatgg tgccaactta ctgatttagt
    33721 gtacgatggt gtctttgagg tgctccagtg gcttccatct ccatcagttg tccctcctgc
    33781 tcagctactg aaggcgtggt gcgtaacggt aaaagtactg ccggacatca gcgctatctc
    33841 tgctctcact gccgtaaaac atggcagcta cagttcactt acaccgcctc tcagcccggt
    33901 acgcaccaga aaatcattga tatggccatg aatggcgttg gatgccgggc aaccgcccgc
    33961 attatgggcg ttggcctcaa cacgatttta cgtcacttaa aaaactcaga ccgcagtcgg
    34021 taacctcacg catacaaccg ggcagtgacg tcattgtctg cgcggaaatg gacgaacagt
    34081 ggggctacgt cggggctaaa tcacgtcagc gctggttatt ttacgcctat ggcaggatgt
    34141 gcaggacggt ggtggcacgc gtctttggtg agcgtactct ggccacgctg gagcgtcttc
    34201 cgggcctgct gtcggccttt gaggtcgtgg tatggatgac ggatggctgg ccgctttatg
    34261 aatcccgcct gaagggagaa ctgcacgtta tcagcaagcg atatacgcag cgaattgagc
    34321 ggcataacca gaatctgagg cagcatctgg caaggctggg caggaagtca ctgtcgttct
    34381 caaaatcggt ggcgctgcat gacaaagtca tcgggcatta tctgaacata aaacactatc
    34441 agtaagttgg agtcattacc aaccagttca ccacctactc gctccgcgat tgtggcagtc
    34501 ttcgaaatcc ccggacgatc cgcctttatg aaagtcttgc tcaattcaaa tcttcaggct
    34561 tatgggttac tactcatgct tggttaaatg accgtttcgt cttaccggaa tcccagcaga
    34621 agaacttggc agagttgaaa cgatctttcc ttgatcctgc actcaagcag ataaatgaga
    34681 aaacaccttt acttgctaag tatagtattg atgattcagg aaaatttctg ttctcaataa
    34741 ttgataagca aaatcccgtc tgacataaat cagcacacat gagcctgtca tttgacaaat
    34801 ttttgtcatg aagatgggcg gatttccaca cagcaccggc gcccggtaag gtgggcggat
    34861 tcccacacgg caccggcgcc cggcaagatg ggcggatttc cacacagcac cggcgcccgg
    34921 taaggtgggc ggatttccac acagcaccgg cgcccggcaa ggtgggcgga ttcccacacg
    34981 gcaccggcgc ccggcaagat gggcggattt ccacacagca ccggcgcccg gtaaggtggg
    35041 cggatttcca cacagcaccg gcgcccggca aggtgggcgg atttccacac agcaccggcg
    35101 cccggcaagg tgggcggatt cccacacggc accggcgcgc ggcaaggtgg gcggattccc
    35161 acacggcacc ggcgcgcggc aaggtgggcg gatttccaca cagcaccggc gcccggtaag
    35221 gtgggcggat tcccacacgg caccggcgcc cggtaaggtg ggcggattcc cacacggcac
    35281 cggcgcccgg taaggtgggc ggattcccac acggcaccgg cgcccggcaa gatgggcgga
    35341 tttccacaca gcaccggcgc ccggtaaggt gggcggattt ccacacagca ccggcgcccg
    35401 gcaaggtggg cggattccca cacggcaccg gcgcccggca agatgggcgg atttccacac
    35461 agcaccggcg cccggtaagg tgggcggatt tccacacagc accggcgccc ggcaaggtgg
    35521 gcggattccc acacggcacc ggcgcgcggc aaggtgggcg gattcccaca cggcaccggc
    35581 gcgcggcaag gtgggcggat ttccacacag caccggcgcc cggcaaggtg ggcggattcc
    35641 cacacggcac cggcgcgcgg caaggtgggc ggattcccac acggcaccgg cgcgcggcaa
    35701 ggtgggcgga tttccacacg gcaccggcgc ccggcaaggt gggccgattc ccatatcgac
    35761 atgtatgtag cttgtgttat ctgtggattg tgcagctcag cgggtcgctg gtcgtatggc
    35821 ggagtgtccc ccgtaaccgg ccgcgtgcgg ccgctaacgc gcagtacggc gccgcgtccc
    35881 gcagacgggc cgccgttccc gcgcgcagca ctgcgcaccc ccgtggggga cgtacggcag
    35941 ctgcgtggcg gtgagcggga ttagggcttt gcagctaccg tgttaagttc cctggtgtcg
    36001 ctgaaatagt tgatgaacat ccccctaagc gtcagcagca agctgccgcc gcttaggccc
    36061 cggaaatcac gccctttacg tcgtaaacgc cgtaaagccc gctcaccggg gttaaaaggg
    36121 attactttga cttcttcatt gctgttcgcg agttaaggct aatcagggca gggggtaggg
    36181 tggcagaatt tatagcccgg caaccggcta cgccgggctt tcggcgccat tttacaacac
    36241 agacggcttt gttgaataaa tcgaactttt gctgagttga aggatcagat cacgcatctt
    36301 cccgacaacg cagaccattc cgtggcaaag caaaagttca aaataaccaa ctggcccacc
    36361 tacaataaag ccctcatcaa ccgtggctcc ataactttct ggctggatga tgaagctatt
    36421 caggcctggt atgagtcggc aacgccttca tcacggggaa gacctcagcg ctattctgat
    36481 ctcgccatca ccaccgttct ggtcattaaa cgcgtgttca ggttgaccct gcgggctgca
    36541 cagggtttta ttgattccat ttttacactg atgaatgttc cgttgcgctg cccggattac
    36601 accagtgtca gcaagcgcgc aaagtcggtt aatgtcagtt tcaaaacgtt cacccggggt
    36661 gaaa
//
