LOCUS       NZ_CP137367            18588 bp    DNA     circular CON 04-NOV-2023
DEFINITION  Klebsiella pneumoniae strain KP86_L3_06.23_ST147_NDM14 plasmid
            unnamed4, complete sequence.
ACCESSION   NZ_CP137367
VERSION     NZ_CP137367.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37951968
            Assembly: GCF_033243425.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 18588)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Klebsiella pneumoniae ST147 - the rise of a multiresistant and
            hypervirulent type
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18588)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-OCT-2023) HCAI, Fungal, AMR, AMU & Sepsis Division,
            United Kingdom Health Security Agency, 61 Colindale Avenue, London,
            London NW9 5EQ, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.9.1-b1780
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 59x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/03/2023 13:42:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,863
            CDSs (total)                      :: 5,740
            Genes (coding)                    :: 5,533
            CDSs (with protein)               :: 5,533
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 207
            CDSs (without protein)            :: 207
            Pseudo Genes (ambiguous residues) :: 0 of 207
            Pseudo Genes (frameshifted)       :: 113 of 207
            Pseudo Genes (incomplete)         :: 97 of 207
            Pseudo Genes (internal stop)      :: 30 of 207
            Pseudo Genes (multiple problems)  :: 28 of 207
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP137367.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18588
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP86_L3_06.23_ST147_NDM14"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed4"
                     /geo_loc_name="United Kingdom: England"
                     /collection_date="2022-12"
                     /genotype="ST147"
     gene            join(18281..18588,1..112)
                     /locus_tag="R5O56_RS29120"
                     /old_locus_tag="R5O56_29115"
     CDS             join(18281..18588,1..112)
                     /locus_tag="R5O56_RS29120"
                     /old_locus_tag="R5O56_29115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            418..681
                     /locus_tag="R5O56_RS29125"
                     /old_locus_tag="R5O56_29120"
     CDS             418..681
                     /locus_tag="R5O56_RS29125"
                     /old_locus_tag="R5O56_29120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            671..970
                     /locus_tag="R5O56_RS29130"
                     /old_locus_tag="R5O56_29125"
     CDS             671..970
                     /locus_tag="R5O56_RS29130"
                     /old_locus_tag="R5O56_29125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1032..1409)
                     /locus_tag="R5O56_RS29135"
                     /old_locus_tag="R5O56_29130"
     CDS             complement(1032..1409)
                     /locus_tag="R5O56_RS29135"
                     /old_locus_tag="R5O56_29130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            1478..1657
                     /locus_tag="R5O56_RS29140"
                     /old_locus_tag="R5O56_29135"
     CDS             1478..1657
                     /locus_tag="R5O56_RS29140"
                     /old_locus_tag="R5O56_29135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1685..2215)
                     /locus_tag="R5O56_RS29145"
                     /old_locus_tag="R5O56_29140"
     CDS             complement(1685..2215)
                     /locus_tag="R5O56_RS29145"
                     /old_locus_tag="R5O56_29140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(2222..2953)
                     /locus_tag="R5O56_RS29150"
                     /old_locus_tag="R5O56_29145"
     CDS             complement(2222..2953)
                     /locus_tag="R5O56_RS29150"
                     /old_locus_tag="R5O56_29145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(2953..4917)
                     /locus_tag="R5O56_RS29155"
                     /old_locus_tag="R5O56_29150"
     CDS             complement(2953..4917)
                     /locus_tag="R5O56_RS29155"
                     /old_locus_tag="R5O56_29150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(6398..6547)
                     /locus_tag="R5O56_RS29160"
                     /old_locus_tag="R5O56_29155"
     CDS             complement(6398..6547)
                     /locus_tag="R5O56_RS29160"
                     /old_locus_tag="R5O56_29155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(6632..6889)
                     /locus_tag="R5O56_RS29165"
                     /old_locus_tag="R5O56_29160"
     CDS             complement(6632..6889)
                     /locus_tag="R5O56_RS29165"
                     /old_locus_tag="R5O56_29160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(6899..8584)
                     /locus_tag="R5O56_RS29170"
                     /old_locus_tag="R5O56_29165"
     CDS             complement(6899..8584)
                     /locus_tag="R5O56_RS29170"
                     /old_locus_tag="R5O56_29165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            8987..9406
                     /locus_tag="R5O56_RS29175"
                     /old_locus_tag="R5O56_29170"
     CDS             8987..9406
                     /locus_tag="R5O56_RS29175"
                     /old_locus_tag="R5O56_29170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            9712..9975
                     /locus_tag="R5O56_RS29180"
                     /old_locus_tag="R5O56_29175"
     CDS             9712..9975
                     /locus_tag="R5O56_RS29180"
                     /old_locus_tag="R5O56_29175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            9965..10264
                     /locus_tag="R5O56_RS29185"
                     /old_locus_tag="R5O56_29180"
     CDS             9965..10264
                     /locus_tag="R5O56_RS29185"
                     /old_locus_tag="R5O56_29180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(10326..10703)
                     /locus_tag="R5O56_RS29190"
                     /old_locus_tag="R5O56_29185"
     CDS             complement(10326..10703)
                     /locus_tag="R5O56_RS29190"
                     /old_locus_tag="R5O56_29185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            10772..10951
                     /locus_tag="R5O56_RS29195"
                     /old_locus_tag="R5O56_29190"
     CDS             10772..10951
                     /locus_tag="R5O56_RS29195"
                     /old_locus_tag="R5O56_29190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(10979..11509)
                     /locus_tag="R5O56_RS29200"
                     /old_locus_tag="R5O56_29195"
     CDS             complement(10979..11509)
                     /locus_tag="R5O56_RS29200"
                     /old_locus_tag="R5O56_29195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(11516..12247)
                     /locus_tag="R5O56_RS29205"
                     /old_locus_tag="R5O56_29200"
     CDS             complement(11516..12247)
                     /locus_tag="R5O56_RS29205"
                     /old_locus_tag="R5O56_29200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(12247..14211)
                     /locus_tag="R5O56_RS29210"
                     /old_locus_tag="R5O56_29205"
     CDS             complement(12247..14211)
                     /locus_tag="R5O56_RS29210"
                     /old_locus_tag="R5O56_29205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(15692..15841)
                     /locus_tag="R5O56_RS29215"
                     /old_locus_tag="R5O56_29210"
     CDS             complement(15692..15841)
                     /locus_tag="R5O56_RS29215"
                     /old_locus_tag="R5O56_29210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(15926..16183)
                     /locus_tag="R5O56_RS29220"
                     /old_locus_tag="R5O56_29215"
     CDS             complement(15926..16183)
                     /locus_tag="R5O56_RS29220"
                     /old_locus_tag="R5O56_29215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(16193..17878)
                     /locus_tag="R5O56_RS29225"
                     /old_locus_tag="R5O56_29220"
     CDS             complement(16193..17878)
                     /locus_tag="R5O56_RS29225"
                     /old_locus_tag="R5O56_29220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     BGC             1899..18588
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          5717..6295
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15011..15589
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2226..2953)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
     Typing          complement(11520..12247)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
ORIGIN
        1 acaatttgcg ggtaccgatt accgcagcaa agacctcaca ccgaaaaaat caaggctact
       61 ggctgacacc atttcagctg tttatctcga tggctatgaa ggcagacagt aagtggattt
      121 accataacgc gtcattacgc gcaccgctca gacgggctca gggcgtttcc ggcggctacg
      181 ggataaaaca ggcaacaacc cccccggaaa actgccggaa acgcgcccga taaattttat
      241 cctaatgcat gcctatgcac gcaactgcat ggcatatgtt ttgacgtaaa atggatgccg
      301 taagcccttt tttaccgact ttctgcttca tcagcctgac tgacacgacc atattctttc
      361 agaccgcccc ctgctaaact tccttcatat tgccgcatta acccgggagg ctccgcaatg
      421 agcaacacta cacactacga aaacgccaac tttcttcggg aactggctga aagcctgccc
      481 cgcatactgc cggaaggtgg cccggacaaa gctgcgctgt tgcagcgact ggctaacgaa
      541 gaactggccc aggcagagta tgaagatcag gttcgcgcca aagtgaccgc cgcccgtgct
      601 gacacgcgtc cgggtatgac cacggaacaa ctccgccagc gcctgcatgg ccgttatcag
      661 gaactgcgcg atgccgtatg acgtggaatg gaagcaggga gccatcgagg atgtaacgac
      721 gctgtttgac tatatcgcgg aaaattcatc cctgtgggat gcgcagaacg ttaccgaccg
      781 ggttctcgct gcggcggaca aactggccga cttcccgcga ctctatgaag tggactcacg
      841 ctatggcgag gacgttcgcc ggatcagtct gatgggacag catgtcctct atgatgttga
      901 tgaccagacc agaaaagtcc gggttctggc cgtggtcggc cagcgccaga atccccatat
      961 tgttctctaa taaccggtga cggggacgca attcattgcg tggccgtcgc cggttggaca
     1021 agcacagcgc gtcagcgttt tccccacggc caccaccggc gcggtgttcc ggccggggtc
     1081 tctgctgtct ccggtttgtg ttccagcagt ctcatggact gcatttcctg ccgtagcccg
     1141 gccacctcct ccctgagtgc ttttatctcc gcgatcaacg cgtcggaggc cattttttca
     1201 gtctcacccg acagtctcaa ctcgtcccgc tcgtgagtct catcctgtct taactcaccg
     1261 tacacccgga taagctcgct ggtatccacc acccggccgc catcagcttc cgtacggtat
     1321 gatacgcggc ctttcgccat atcccgatac agggaacttc gggctttacc cgtcagttcc
     1381 gtcgcctgtc tcaccgtcac ccacgccatt gtctcacccc gctatttttg agacagtata
     1441 cctgacaggc gcacaccatg cccggaagga aagaatcatg acaaaacagg aaaaaacagc
     1501 cctcaatatg gctaaattta ttaaggagca gtcgctgcta ttgctcgata aactgaatga
     1561 gctggatatg gataccccgg ccgacatgtg cgagcggcta cacgaggatg cggaaacact
     1621 ctggcaggtg atgcgggata agctcgggga ggaataacag caccggcatg gccggtgctg
     1681 gcatttattt tttgccgaac ggccaccacc ggcgggcagg tttgtcctcc ggcagttcag
     1741 gtaccggcac gttaaaatag cggctgttat attcccgcat cagctccgct ttcagcttct
     1801 cgttcaccgc gctttccccg tgccgctcac tcaccacgtc aatcatcgcg ttaatctgct
     1861 ccggtgagca cttcccggca tcaaccacct gcacaccgtt ctcgatggcg aaccgctcca
     1921 ccttgcgata gaggtaatca cacagcttca ttcctgtggg tttgttccgt tcccattgcg
     1981 gatttttacc agtgaaaaag tacgtggctt tttcgtcgct gttgagccgc tcgtcataca
     2041 tcccgatgga tttcatcatc gccagatgct gggcccggtc gacaaaacag aaaacatacg
     2101 ccccggtctg ccaggcgagc accaccatat cttccagatg ctcgctggtc ggcatgatgc
     2161 agcgctcgcc gttccggtcc tccgcgtctt caataaatac catgtacagc gccataatcc
     2221 ctcactccgt tgtcataaat ttaaagcacg caaacaaccg ttcacgatcc agctctgccg
     2281 ttttgcgggc ctcgccggtc tgtgggttca cgatttcatc caccgacagg attgcccgct
     2341 gcaccctgac ctgcgtcgcc cggtccgggc agatgtacca gatttcatcg atgccgttag
     2401 ctttgcggtt gaacagatac ccggacacca cttcctgata ccggcgacgg ctcttgacgg
     2461 tgcgctccac ctcaaacgcc accgttttac cgtccagctc cgccagggcg tccggcactt
     2521 tcatgccttt aagactcaga cggtgcagaa tgcgccagcc ggtggcccct ctggcttcca
     2581 tatcaaggcg cagggattgc acggccagcc ggtgcggcag atgtgctgcc gacacccttg
     2641 acggctgaaa cggaataaca tccgccagcg gttcgtcctc gtcgaacgag aacgccacgc
     2701 catgcggcgt cagcccccac acgctgacct gacggccgtc caccggatat ttggtccgga
     2761 ccagcagccc tttcgccacc aggctgtcga ggaagcggta gaccggctgc accgccgcaa
     2821 tccccagccg ccgcgcaacc agctccgccg tggaacacag ctcttcccgc aaccagcgca
     2881 gggtcagccg ggttttctcc gcgttccgcg cctgtcgttt cgcgtggctg acgttgtaca
     2941 gctccagcgc catcagtaaa tccccgcaaa atcatcatcc gctttcggcc cgccgccgtc
     3001 ggccgggggc cggaactccg ccaggggatc ggttttcgcc agcaccggga aacgctgcaa
     3061 cgggatttcc cggcgctcaa cccgcagcgg actgctgaac gccatccggg ccacacccag
     3121 cccggtcatg accgcgaacc cgtccggcag gtgttgcagg gtgttcacgt caaacagcgg
     3181 ccgcgcctcc ttctggatga agctgtcccc gctgatatgc tccacgttcc ccgcctcccg
     3241 gctggcacgg cggcgctcca cgtccaccct gatttccccg gtctgccccg ccgcccactg
     3301 cgcggactcc aggctggccg cccggtaaaa ccagcggatc ggcgtgttat ccagtaccgt
     3361 ggttttcaca aattcagcgg gcagatcctg cccgcactgc ccgaaatcgc ccagcgactg
     3421 gtgcgcgagc aacagattgc agtcccggct gcgcagcgtc cccagtgcgt tcagtacata
     3481 cttcgacagc agatatttaa tttcatcgag catcacgctg acgtgtggcc actcccggaa
     3541 ctcgtcccgc gcaatgatga tttgcgcgca gcgggcaaac agcatttttt gcacacggat
     3601 caccgcctcg tcgtccatcg agccgataac gtacaggcag ccgccgccgt tgataatccc
     3661 cgccacatcg atgccactgt ccgtctgcag gacgctcagg tcagcgacgt tttccagcct
     3721 agtgatcaac cccttcacgt cctttttcag ggcctccggc agcgcgtacg ccgccgccag
     3781 cacctgctga atgtttgccc cctgcggaaa ctgctccgca atcagcttcg ccgctttctg
     3841 ctcgctgatg cggtagtggt ccgccacgtc gccggtctcg cccaggttaa gcccggcaat
     3901 cagcaggttt ttcagcgcgt actggtcgag atcgcggaac agattcagct gcgccggttt
     3961 ccccggccgc agatccagca gggtgaagtc cggacagtgc gcccggaaga cgtgcggcgc
     4021 ccatgcgtcc cctttggggt cgaagtacac caccgcgtcc ccgaaatcgc gtacgcagcg
     4081 aatgagcgcg ttggtggcca tcacgctctt gccgctcccg ggcaggccga ggatctgaat
     4141 gttggtcttg cgccaggtat cacgcggaac cagcaccggc ttgccctgct catccttacc
     4201 cagaaacacc gcctgctcct gccgggcctg ctccgaggaa aaatcggcca gcgcattaac
     4261 cggtaccggc tccccgaaat gcaggtggcg cacgtcggtc atctctcctg tccgctggct
     4321 gctgcgccgg ctctcctgat tcagtttcgc gttcaccgcc tcgtcagcag ccgcaaaatg
     4381 accgtcaagc agcaggaacg ccagcagccg cgccaacaca atcccgacag ccagcccgcc
     4441 cgcgcaccag gcaatcccga acaggttagc cggctgcagc aggtaataat ctgcgtttgc
     4501 gtagaggtcc ggacgcagga cggtttctcc ccagctctcg ataaacacgg cgacaaccag
     4561 cccccccaga agggccagac cggccgcgcc ggtcagccag tacgcgtagt tccagacatg
     4621 tcgacgtgcc ctgaccatcc gcccgggcga atccagcgag gccagcaccg aaaatggcgc
     4681 tggccgttta ttatcgcgct tatagcgatc ggcatactcc cgtcgctcct tatgactcag
     4741 ccccacaaaa cgcatccgtc cggcccaaag ttcagccaga ccgaaaaaca ggccgataac
     4801 taggaaagcc ccggccagac cgtaatactc ctggtacagc cagctgaccc acggataaat
     4861 ctgccgggcc agctccggaa tgtgccactt ccaggcaagc gaatccgtat taaacatgtt
     4921 ctctctcctt cagacgatgg tttgccggcg tgatgtgcag cccccgctgc acaagccgcg
     4981 gacatgcccc aaggcatggc ggcggcggtc acgtccgtgg tgattgcgtt cagctttcac
     5041 cacggaggcc agcctctttc cgccccatgc ggaaaaggcg cagccccgga ggaacaacga
     5101 gcacgcccca gcgtgtgaga ggaaaaggcg gcaccccagt gcggtctttt ccggtgttcc
     5161 ggcccccgtc agagttcgcc atagcgagcg gctgaccacc cgcaaaatca ggagcagctt
     5221 tgctgcttcg ccaggtgcgt ccagcaccgt ggatttttgt gggtggtcag gcgtgagcct
     5281 gacgggggcc gggtgaattt ctggcgtggc cggcgtccag ccggacggag ccagaaagag
     5341 ggggagagac cgtgcgtcgg tggcgtccag ccagcgtaag caggggatat ccccctgagg
     5401 tcagccacgc cctcgcgggg atgacctgta tttctccgta aggagaaaaa agcaacagag
     5461 ataggttaac gtaaaatgtt cagcgaaaaa ccgatatgat tcacctatcc tggtaattta
     5521 ttatcaggga atataaagac ttaatcaggg gacaatatgc cacatcagcg cgtccggtgt
     5581 ccgtcttgta ggtgccgggg aaattgcgcc tcctcgctca ctcggtcgct acgctccggc
     5641 cgtgagactg cggcgggcgc tgcggacaca tgcaaagtta cccacagatt ccgtgaataa
     5701 gcaggggact aacatgtgag gcaaaacggc aaggccacgc aggtggcgtt tttccatagg
     5761 ctccgccctc ctgactgagt tcacataaac agacgctttt tcggtgcatc tgtgggagcc
     5821 ggtggctcaa ccatgaatca gtcaggagtg gcgaaacccg acaggactta aagatcatca
     5881 ccgtttccga tgaatcgctc cctcttgcgc tctcctgttc caaccctgcc gtttcccgga
     5941 tacctgttcc gcctttctcc cttgcgggaa gtgtggcgct ttctcatagc tcacactctg
     6001 gtatctcggc tcggtgtagg tcgttcgctc caagctgggc tgtaagcaag aaccccccgt
     6061 tcagcccgac tgctgcgcct tatccggtaa ctgttcactt gagtccaacc cggaaaagca
     6121 cgcaaaacgc cactggcagc agccattggt aactgggagt tcgcagagga tttgtttagc
     6181 taaacacgcg gttgctcttg aagtgtgcgc caaagtccgg ctacactgga aggacagatt
     6241 tggttgctgt gctctgcgaa agccagttac cacggttaag cagttcccca actgacttaa
     6301 ccttcgatca aaccacctcc ccaggtggtt ttttcgttta cagggcaaaa gattacgcgc
     6361 agaaaaaaag gatctcaaga agatcctttg atcttttcta ctgaaccgcg atccccgtca
     6421 gttcagagga ggacgatggt gccaccgttc caccctgaac atcccggata tagtttgcct
     6481 gacatgcgac cagaagaaag cctgaaaaaa tcaatataaa aagaaaaaca acctttacct
     6541 ttttcatata ccttccctgt atttaaaaac cccggtattc atccctgaac accggaagtc
     6601 tgtatttcaa atcatccttg ataacttttg cttaccagtt accatcccgg taaacaaagg
     6661 atacaaagta atcaaattta ctaatatcga ttacattttt aaagtgtggc tgtaatatcg
     6721 aaacccatga tttttcaaca tcaaaccaac cattattaat attatccttt aaaggcatcc
     6781 ccagactttc aatgacagaa ccatcatcac cgaagtcttt tgagtattca ccacctttaa
     6841 actcttcggt tttcttatca aaccaatgaa tatgtaattt aagccccata tttacctctt
     6901 aaagatattt tttaatgttt cgttttggat ccggcccttt aacctgctta cccgtttttg
     6961 gatcgaatgc cccgaggtgt tcgccatcac tggcgcggta cccttcaagc tcaccgtgct
     7021 gggaatccca ttcataaatt ttacgctttt tatcaccata ccatcgggcc cgcttaccac
     7081 caccaccttg tttaggggtt ttaggtttac cctctttcaa ctctcccaac cccttaatat
     7141 cttcagtctt gggatcagga aaataatcat ggccgtaatc tttagttccc ttacgaggtt
     7201 ttttcttttc ctcatttaat ttattttctg catccttcgc ttttttctcc ttttgtttcc
     7261 ggctctccat cgccccggaa agcgcagcct tatccctgga taaggattca ttcatttcgt
     7321 ttaaagatgt ctgggcagct tttaatttct cattctgatt ctgaatatcc ttatcaagat
     7381 agcgaacctg atcctgccac ccggagccat attcatgagg cgggttataa gtcacaaaat
     7441 catctttatt tgcctctgcc tcttttacct ttttatcggc ttcctgaaca gcagcccttg
     7501 caccggggat cgccttctct gtcgatgcaa tgcgactgtt taaggtcgca atatttttat
     7561 cttcagcatc cagctcagct ttcgctttat catactctct tttcagcccc tcttccgggt
     7621 gagcagcgtc ccatgcctgc tggcgacgct tttcttcctc cagacgctgt tttacctgtg
     7681 ccggagtaag aacatccgtc accgacacat agaccggttt ctgtccgctc tctttcggga
     7741 aacgaataac ggcttcacgg gagttaccac cggccgtaaa accagccgga cgtgaatcac
     7801 ctttttcagc aataatgcct tttggcgggg ctttcgcggc cggaacacct ttaggtacgc
     7861 tcacctgcag agacgggaga cccggaatcg acacactgaa tacccccgga cgttttgtcg
     7921 gtttcgcatc caccacagga acactcattg gccggccggt gacaaccgca atatgctgcc
     7981 gctcgtcctt cacaatatcc gccacacgtt tagtgacgct gaccgtcgcc tggtccagcg
     8041 gcagggagct gaccggcgtc tccgttaccg tgtctgccgg caatgacgtc acgatttttg
     8101 acatcatttt cggatcatct tttgctatct cagaaggcag cactccgtaa atcgcaatcc
     8161 cccacagacc aaacttaaac ggacctttca gggcagccag cacatcagca acagcggccg
     8221 acaacgcatc gccggaaacg gataaagcca gtccttcagc ccccggagtg gccaaggcag
     8281 gcagaccgaa ggccatcgcg gtggccgaag actgtccgcc accagagctc ccgctatgat
     8341 tgccgctgtt accgccatta ccaccgggtt tactcccgcc gttaccaaac tcccccgggt
     8401 tatagttatg aatatccccg ttaggtgtat gcgtcgtacc ccagcccggc ccgctgtttg
     8461 gatccgtacc accacctgat gaagggccac ctttacctga tgtaccgttc acattcccac
     8521 tggcctgacc accattgtgt cccagacctg aattacccgg acctcgtccg tctccgccac
     8581 tcatatactt ttcctctttg acttttaaaa caataaacta aaataaaata ctgtacatat
     8641 aaccactggt tttatataca gtataaaaat tacgctgcct tgtttttcat gtcaagtctg
     8701 taaatttgcg tttttgtgaa aatgatcaaa aaaacagcca ctcacaccat gcgcaatccc
     8761 ctccagatgc aacaaaaacc agcacaaacg gcgccgttct ccggcctcag tatgttttac
     8821 tgaaatcatt atatgagata ccagaaagcc ccctccggga caggaaaaga aacggggggt
     8881 ctggttcggg ttgttcggtc actgaacacg gtcagaaact gatgataaga tagcctgcgg
     8941 atatataact caatgagaaa aaagaattaa aggtaaggag acgctcatga gacgttccgg
     9001 cagcaaactg tgtcttatcg ccatgataac agcgacagca actctcactg cctgtgctcc
     9061 aaagggcagc gtggaacagc atacccggca ttacgtatat gcttcagatg acggttttga
     9121 tcccaatttt tccacccaga aagctgacac aacacgaatg atggtgcctt ttttccggca
     9181 gttctgggat atgggcgcaa aggataaagc gaccggaaaa tcacggagtg atgtgcagca
     9241 acgcattcag cagtttcaca gtcaggaatt tttaaactca ctccaaggca caacacaatt
     9301 tgcgggtacc gattaccgca gcaaagacct cacaccgaaa aaatcaaggc tactggctga
     9361 caccatttca gctgtttatc tcgatggcta tgaaggcaga cagtaagtgg atttaccata
     9421 acgcgtcatt acgcgcaccg ctcagacggg ctcagggcgt ttccggcggc tacgggataa
     9481 aacaggcaac aacccccccg gaaaactgcc ggaaacgcgc ccgataaatt ttatcctaat
     9541 gcatgcctat gcacgcaact gcatggcata tgttttgacg taaaatggat gccgtaagcc
     9601 cttttttacc gactttctgc ttcatcagcc tgactgacac gaccatattc tttcagaccg
     9661 ccccctgcta aacttccttc atattgccgc attaacccgg gaggctccgc aatgagcaac
     9721 actacacact acgaaaacgc caactttctt cgggaactgg ctgaaagcct gccccgcata
     9781 ctgccggaag gtggcccgga caaagctgcg ctgttgcagc gactggctaa cgaagaactg
     9841 gcccaggcag agtatgaaga tcaggttcgc gccaaagtga ccgccgcccg tgctgacacg
     9901 cgtccgggta tgaccacgga acaactccgc cagcgcctgc atggccgtta tcaggaactg
     9961 cgcgatgccg tatgacgtgg aatggaagca gggagccatc gaggatgtaa cgacgctgtt
    10021 tgactatatc gcggaaaatt catccctgtg ggatgcgcag aacgttaccg accgggttct
    10081 cgctgcggcg gacaaactgg ccgacttccc gcgactctat gaagtggact cacgctatgg
    10141 cgaggacgtt cgccggatca gtctgatggg acagcatgtc ctctatgatg ttgatgacca
    10201 gaccagaaaa gtccgggttc tggccgtggt cggccagcgc cagaatcccc atattgttct
    10261 ctaataaccg gtgacgggga cgcaattcat tgcgtggccg tcgccggttg gacaagcaca
    10321 gcgcgtcagc gttttcccca cggccaccac cggcgcggtg ttccggccgg ggtctctgct
    10381 gtctccggtt tgtgttccag cagtctcatg gactgcattt cctgccgtag cccggccacc
    10441 tcctccctga gtgcttttat ctccgcgatc aacgcgtcgg aggccatttt ttcagtctca
    10501 cccgacagtc tcaactcgtc ccgctcgtga gtctcatcct gtcttaactc accgtacacc
    10561 cggataagct cgctggtatc caccacccgg ccgccatcag cttccgtacg gtatgatacg
    10621 cggcctttcg ccatatcccg atacagggaa cttcgggctt tacccgtcag ttccgtcgcc
    10681 tgtctcaccg tcacccacgc cattgtctca ccccgctatt tttgagacag tatacctgac
    10741 aggcgcacac catgcccgga aggaaagaat catgacaaaa caggaaaaaa cagccctcaa
    10801 tatggctaaa tttattaagg agcagtcgct gctattgctc gataaactga atgagctgga
    10861 tatggatacc ccggccgaca tgtgcgagcg gctacacgag gatgcggaaa cactctggca
    10921 ggtgatgcgg gataagctcg gggaggaata acagcaccgg catggccggt gctggcattt
    10981 attttttgcc gaacggccac caccggcggg caggtttgtc ctccggcagt tcaggtaccg
    11041 gcacgttaaa atagcggctg ttatattccc gcatcagctc cgctttcagc ttctcgttca
    11101 ccgcgctttc cccgtgccgc tcactcacca cgtcaatcat cgcgttaatc tgctccggtg
    11161 agcacttccc ggcatcaacc acctgcacac cgttctcgat ggcgaaccgc tccaccttgc
    11221 gatagaggta atcacacagc ttcattcctg tgggtttgtt ccgttcccat tgcggatttt
    11281 taccagtgaa aaagtacgtg gctttttcgt cgctgttgag ccgctcgtca tacatcccga
    11341 tggatttcat catcgccaga tgctgggccc ggtcgacaaa acagaaaaca tacgccccgg
    11401 tctgccaggc gagcaccacc atatcttcca gatgctcgct ggtcggcatg atgcagcgct
    11461 cgccgttccg gtcctccgcg tcttcaataa ataccatgta cagcgccata atccctcact
    11521 ccgttgtcat aaatttaaag cacgcaaaca accgttcacg atccagctct gccgttttgc
    11581 gggcctcgcc ggtctgtggg ttcacgattt catccaccga caggattgcc cgctgcaccc
    11641 tgacctgcgt cgcccggtcc gggcagatgt accagatttc atcgatgccg ttagctttgc
    11701 ggttgaacag atacccggac accacttcct gataccggcg acggctcttg acggtgcgct
    11761 ccacctcaaa cgccaccgtt ttaccgtcca gctccgccag ggcgtccggc actttcatgc
    11821 ctttaagact cagacggtgc agaatgcgcc agccggtggc ccctctggct tccatatcaa
    11881 ggcgcaggga ttgcacggcc agccggtgcg gcagatgtgc tgccgacacc cttgacggct
    11941 gaaacggaat aacatccgcc agcggttcgt cctcgtcgaa cgagaacgcc acgccatgcg
    12001 gcgtcagccc ccacacgctg acctgacggc cgtccaccgg atatttggtc cggaccagca
    12061 gccctttcgc caccaggctg tcgaggaagc ggtagaccgg ctgcaccgcc gcaatcccca
    12121 gccgccgcgc aaccagctcc gccgtggaac acagctcttc ccgcaaccag cgcagggtca
    12181 gccgggtttt ctccgcgttc cgcgcctgtc gtttcgcgtg gctgacgttg tacagctcca
    12241 gcgccatcag taaatccccg caaaatcatc atccgctttc ggcccgccgc cgtcggccgg
    12301 gggccggaac tccgccaggg gatcggtttt cgccagcacc gggaaacgct gcaacgggat
    12361 ttcccggcgc tcaacccgca gcggactgct gaacgccatc cgggccacac ccagcccggt
    12421 catgaccgcg aacccgtccg gcaggtgttg cagggtgttc acgtcaaaca gcggccgcgc
    12481 ctccttctgg atgaagctgt ccccgctgat atgctccacg ttccccgcct cccggctggc
    12541 acggcggcgc tccacgtcca ccctgatttc cccggtctgc cccgccgccc actgcgcgga
    12601 ctccaggctg gccgcccggt aaaaccagcg gatcggcgtg ttatccagta ccgtggtttt
    12661 cacaaattca gcgggcagat cctgcccgca ctgcccgaaa tcgcccagcg actggtgcgc
    12721 gagcaacaga ttgcagtccc ggctgcgcag cgtccccagt gcgttcagta catacttcga
    12781 cagcagatat ttaatttcat cgagcatcac gctgacgtgt ggccactccc ggaactcgtc
    12841 ccgcgcaatg atgatttgcg cgcagcgggc aaacagcatt ttttgcacac ggatcaccgc
    12901 ctcgtcgtcc atcgagccga taacgtacag gcagccgccg ccgttgataa tccccgccac
    12961 atcgatgcca ctgtccgtct gcaggacgct caggtcagcg acgttttcca gcctagtgat
    13021 caaccccttc acgtcctttt tcagggcctc cggcagcgcg tacgccgccg ccagcacctg
    13081 ctgaatgttt gccccctgcg gaaactgctc cgcaatcagc ttcgccgctt tctgctcgct
    13141 gatgcggtag tggtccgcca cgtcgccggt ctcgcccagg ttaagcccgg caatcagcag
    13201 gtttttcagc gcgtactggt cgagatcgcg gaacagattc agctgcgccg gtttccccgg
    13261 ccgcagatcc agcagggtga agtccggaca gtgcgcccgg aagacgtgcg gcgcccatgc
    13321 gtcccctttg gggtcgaagt acaccaccgc gtccccgaaa tcgcgtacgc agcgaatgag
    13381 cgcgttggtg gccatcacgc tcttgccgct cccgggcagg ccgaggatct gaatgttggt
    13441 cttgcgccag gtatcacgcg gaaccagcac cggcttgccc tgctcatcct tacccagaaa
    13501 caccgcctgc tcctgccggg cctgctccga ggaaaaatcg gccagcgcat taaccggtac
    13561 cggctccccg aaatgcaggt ggcgcacgtc ggtcatctct cctgtccgct ggctgctgcg
    13621 ccggctctcc tgattcagtt tcgcgttcac cgcctcgtca gcagccgcaa aatgaccgtc
    13681 aagcagcagg aacgccagca gccgcgccaa cacaatcccg acagccagcc cgcccgcgca
    13741 ccaggcaatc ccgaacaggt tagccggctg cagcaggtaa taatctgcgt ttgcgtagag
    13801 gtccggacgc aggacggttt ctccccagct ctcgataaac acggcgacaa ccagcccccc
    13861 cagaagggcc agaccggccg cgccggtcag ccagtacgcg tagttccaga catgtcgacg
    13921 tgccctgacc atccgcccgg gcgaatccag cgaggccagc accgaaaatg gcgctggccg
    13981 tttattatcg cgcttatagc gatcggcata ctcccgtcgc tccttatgac tcagccccac
    14041 aaaacgcatc cgtccggccc aaagttcagc cagaccgaaa aacaggccga taactaggaa
    14101 agccccggcc agaccgtaat actcctggta cagccagctg acccacggat aaatctgccg
    14161 ggccagctcc ggaatgtgcc acttccaggc aagcgaatcc gtattaaaca tgttctctct
    14221 ccttcagacg atggtttgcc ggcgtgatgt gcagcccccg ctgcacaagc cgcggacatg
    14281 ccccaaggca tggcggcggc ggtcacgtcc gtggtgattg cgttcagctt tcaccacgga
    14341 ggccagcctc tttccgcccc atgcggaaaa ggcgcagccc cggaggaaca acgagcacgc
    14401 cccagcgtgt gagaggaaaa ggcggcaccc cagtgcggtc ttttccggtg ttccggcccc
    14461 cgtcagagtt cgccatagcg agcggctgac cacccgcaaa atcaggagca gctttgctgc
    14521 ttcgccaggt gcgtccagca ccgtggattt ttgtgggtgg tcaggcgtga gcctgacggg
    14581 ggccgggtga atttctggcg tggccggcgt ccagccggac ggagccagaa agagggggag
    14641 agaccgtgcg tcggtggcgt ccagccagcg taagcagggg atatccccct gaggtcagcc
    14701 acgccctcgc ggggatgacc tgtatttctc cgtaaggaga aaaaagcaac agagataggt
    14761 taacgtaaaa tgttcagcga aaaaccgata tgattcacct atcctggtaa tttattatca
    14821 gggaatataa agacttaatc aggggacaat atgccacatc agcgcgtccg gtgtccgtct
    14881 tgtaggtgcc ggggaaattg cgcctcctcg ctcactcggt cgctacgctc cggccgtgag
    14941 actgcggcgg gcgctgcgga cacatgcaaa gttacccaca gattccgtga ataagcaggg
    15001 gactaacatg tgaggcaaaa cggcaaggcc acgcaggtgg cgtttttcca taggctccgc
    15061 cctcctgact gagttcacat aaacagacgc tttttcggtg catctgtggg agccggtggc
    15121 tcaaccatga atcagtcagg agtggcgaaa cccgacagga cttaaagatc atcaccgttt
    15181 ccgatgaatc gctccctctt gcgctctcct gttccaaccc tgccgtttcc cggatacctg
    15241 ttccgccttt ctcccttgcg ggaagtgtgg cgctttctca tagctcacac tctggtatct
    15301 cggctcggtg taggtcgttc gctccaagct gggctgtaag caagaacccc ccgttcagcc
    15361 cgactgctgc gccttatccg gtaactgttc acttgagtcc aacccggaaa agcacgcaaa
    15421 acgccactgg cagcagccat tggtaactgg gagttcgcag aggatttgtt tagctaaaca
    15481 cgcggttgct cttgaagtgt gcgccaaagt ccggctacac tggaaggaca gatttggttg
    15541 ctgtgctctg cgaaagccag ttaccacggt taagcagttc cccaactgac ttaaccttcg
    15601 atcaaaccac ctccccaggt ggttttttcg tttacagggc aaaagattac gcgcagaaaa
    15661 aaaggatctc aagaagatcc tttgatcttt tctactgaac cgcgatcccc gtcagttcag
    15721 aggaggacga tggtgccacc gttccaccct gaacatcccg gatatagttt gcctgacatg
    15781 cgaccagaag aaagcctgaa aaaatcaata taaaaagaaa aacaaccttt acctttttca
    15841 tataccttcc ctgtatttaa aaaccccggt attcatccct gaacaccgga agtctgtatt
    15901 tcaaatcatc cttgataact tttgcttacc agttaccatc ccggtaaaca aaggatacaa
    15961 agtaatcaaa tttactaata tcgattacat ttttaaagtg tggctgtaat atcgaaaccc
    16021 atgatttttc aacatcaaac caaccattat taatattatc ctttaaaggc atccccagac
    16081 tttcaatgac agaaccatca tcaccgaagt cttttgagta ttcaccacct ttaaactctt
    16141 cggttttctt atcaaaccaa tgaatatgta atttaagccc catatttacc tcttaaagat
    16201 attttttaat gtttcgtttt ggatccggcc ctttaacctg cttacccgtt tttggatcga
    16261 atgccccgag gtgttcgcca tcactggcgc ggtacccttc aagctcaccg tgctgggaat
    16321 cccattcata aattttacgc tttttatcac cataccatcg ggcccgctta ccaccaccac
    16381 cttgtttagg ggttttaggt ttaccctctt tcaactctcc caacccctta atatcttcag
    16441 tcttgggatc aggaaaataa tcatggccgt aatctttagt tcccttacga ggttttttct
    16501 tttcctcatt taatttattt tctgcatcct tcgctttttt ctccttttgt ttccggctct
    16561 ccatcgcccc ggaaagcgca gccttatccc tggataagga ttcattcatt tcgtttaaag
    16621 atgtctgggc agcttttaat ttctcattct gattctgaat atccttatca agatagcgaa
    16681 cctgatcctg ccacccggag ccatattcat gaggcgggtt ataagtcaca aaatcatctt
    16741 tatttgcctc tgcctctttt acctttttat cggcttcctg aacagcagcc cttgcaccgg
    16801 ggatcgcctt ctctgtcgat gcaatgcgac tgtttaaggt cgcaatattt ttatcttcag
    16861 catccagctc agctttcgct ttatcatact ctcttttcag cccctcttcc gggtgagcag
    16921 cgtcccatgc ctgctggcga cgcttttctt cctccagacg ctgttttacc tgtgccggag
    16981 taagaacatc cgtcaccgac acatagaccg gtttctgtcc gctctctttc gggaaacgaa
    17041 taacggcttc acgggagtta ccaccggccg taaaaccagc cggacgtgaa tcaccttttt
    17101 cagcaataat gccttttggc ggggctttcg cggccggaac acctttaggt acgctcacct
    17161 gcagagacgg gagacccgga atcgacacac tgaatacccc cggacgtttt gtcggtttcg
    17221 catccaccac aggaacactc attggccggc cggtgacaac cgcaatatgc tgccgctcgt
    17281 ccttcacaat atccgccaca cgtttagtga cgctgaccgt cgcctggtcc agcggcaggg
    17341 agctgaccgg cgtctccgtt accgtgtctg ccggcaatga cgtcacgatt tttgacatca
    17401 ttttcggatc atcttttgct atctcagaag gcagcactcc gtaaatcgca atcccccaca
    17461 gaccaaactt aaacggacct ttcagggcag ccagcacatc agcaacagcg gccgacaacg
    17521 catcgccgga aacggataaa gccagtcctt cagcccccgg agtggccaag gcaggcagac
    17581 cgaaggccat cgcggtggcc gaagactgtc cgccaccaga gctcccgcta tgattgccgc
    17641 tgttaccgcc attaccaccg ggtttactcc cgccgttacc aaactccccc gggttatagt
    17701 tatgaatatc cccgttaggt gtatgcgtcg taccccagcc cggcccgctg tttggatccg
    17761 taccaccacc tgatgaaggg ccacctttac ctgatgtacc gttcacattc ccactggcct
    17821 gaccaccatt gtgtcccaga cctgaattac ccggacctcg tccgtctccg ccactcatat
    17881 acttttcctc tttgactttt aaaacaataa actaaaataa aatactgtac atataaccac
    17941 tggttttata tacagtataa aaattacgct gccttgtttt tcatgtcaag tctgtaaatt
    18001 tgcgtttttg tgaaaatgat caaaaaaaca gccactcaca ccatgcgcaa tcccctccag
    18061 atgcaacaaa aaccagcaca aacggcgccg ttctccggcc tcagtatgtt ttactgaaat
    18121 cattatatga gataccagaa agccccctcc gggacaggaa aagaaacggg gggtctggtt
    18181 cgggttgttc ggtcactgaa cacggtcaga aactgatgat aagatagcct gcggatatat
    18241 aactcaatga gaaaaaagaa ttaaaggtaa ggagacgctc atgagacgtt ccggcagcaa
    18301 actgtgtctt atcgccatga taacagcgac agcaactctc actgcctgtg ctccaaaggg
    18361 cagcgtggaa cagcataccc ggcattacgt atatgcttca gatgacggtt ttgatcccaa
    18421 tttttccacc cagaaagctg acacaacacg aatgatggtg ccttttttcc ggcagttctg
    18481 ggatatgggc gcaaaggata aagcgaccgg aaaatcacgg agtgatgtgc agcaacgcat
    18541 tcagcagttt cacagtcagg aatttttaaa ctcactccaa ggcacaac
//
