LOCUS       NZ_CP136525            37136 bp    DNA     circular CON 20-OCT-2023
DEFINITION  Staphylococcus aureus strain BAA-1556_Catania_SCV plasmid pUSA03,
            complete sequence.
ACCESSION   NZ_CP136525
VERSION     NZ_CP136525.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37705137
            Assembly: GCF_032808505.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 37136)
  AUTHORS   Bivona,D.A., Bonomo,C., Colombini,L., Bonacci,P.G., Privitera,G.F.,
            Caruso,G., Caraci,F., Santoro,F., Musso,N., Bongiorno,D.,
            Iannelli,F. and Stefani,S.
  TITLE     Phagosomal escape, intracellular survival, and small colony variants
            formation of USA300 Staphylococcus aureus in RAW 264.7 murine
            macrophages
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 37136)
  AUTHORS   Bivona,D.A., Bonomo,C., Colombini,L., Bonacci,P.G., Privitera,G.F.,
            Caruso,G., Caraci,F., Santoro,F., Musso,N., Bongiorno,D.,
            Iannelli,F. and Stefani,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-OCT-2023) Department of Medical Biotechnologies,
            University of Siena, viale Bracci, 16, Siena 53100, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-OCT-2023
            Assembly Method :: Flye v. 2.7.1; Medaka v. 0.7.1; Pilon v. 1.22
            Assembly Name                     :: USA300_BAA-1556_Catania_SCV
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 181x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/20/2023 13:22:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,939
            CDSs (total)                      :: 2,857
            Genes (coding)                    :: 2,778
            CDSs (with protein)               :: 2,778
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 43 of 79
            Pseudo Genes (incomplete)         :: 38 of 79
            Pseudo Genes (internal stop)      :: 15 of 79
            Pseudo Genes (multiple problems)  :: 16 of 79
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP136525.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..37136
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BAA-1556_Catania_SCV"
                     /isolation_source="University of Catania"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA03"
                     /geo_loc_name="Italy:Catania"
                     /lat_lon="37.52 N 15.06 E"
                     /collection_date="2021"
                     /collected_by="University of Catania"
     gene            101..1060
                     /locus_tag="RZS16_RS14475"
                     /old_locus_tag="RZS16_14470"
     CDS             101..1060
                     /locus_tag="RZS16_RS14475"
                     /old_locus_tag="RZS16_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002484669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000043161.1"
                     /translation="MSKQFFTVEENYKERFYQLPKVFFTNPNYKDLSNDAKIAYAILRD
                     RLQLSIKNNWIDTEGNIYFIYTVADLEVILNCGNKKITKIKKELENVDLLIQKRQGLNK
                     PNLLYLLKPAITKNDIYEIDKAENEVEALQDKEVSKGHVQKCQKDTSRNVKRTRLEMSK
                     GHTNDTDFIDTDFIDTESNDMNNMNDTNQHSNHSNHFSNIHDKESLKYIELQELPELIK
                     SYINNFSYEEVKSIKSVILKAKKSFNNKYDTFYMLEDIDEELLLVLKRFKGYLVKKQEK
                     VANMEGYLMRSIIAELEEMHSTIMRRKNMENNPLSLFN"
                     /name="replication initiator protein A"
     gene            1179..1853
                     /locus_tag="RZS16_RS14480"
                     /old_locus_tag="RZS16_14475"
     CDS             1179..1853
                     /locus_tag="RZS16_RS14480"
                     /old_locus_tag="RZS16_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            2162..5236
                     /gene="mupA"
                     /locus_tag="RZS16_RS14485"
                     /old_locus_tag="RZS16_14480"
     ARG             2163..5233
                     /name="mupA"
                     /gene="mupA"
                     /gene_name="mupirocin-resistant isoleucine--tRNA ligase
                     MupA"
                     /tool="amrfinderplus"
                     /drug_class="MUPIROCIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5306..5704
                     /locus_tag="RZS16_RS14490"
                     /old_locus_tag="RZS16_14485"
     CDS             5306..5704
                     /locus_tag="RZS16_RS14490"
                     /old_locus_tag="RZS16_14485"
                     /inference="COORDINATES: protein motif:HMM:NF015818.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="WP_000282187.1"
                     /translation="MYNFDYSKLPIKNIQKIFPIAGGYVNLSFSVDASNKKYFLKLQPN
                     TKSNFFDYELSSLKELTDKNIPVPQIINKGELDNNSFLLLEFIENGHAYPESYRKLGKI
                     VANMHKNINSLNLFGFSHNFGSVAKLNL"
                     /name="fructosamine kinase family protein"
     gene            5734..6408
                     /locus_tag="RZS16_RS14495"
                     /old_locus_tag="RZS16_14490"
     CDS             5734..6408
                     /locus_tag="RZS16_RS14495"
                     /old_locus_tag="RZS16_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001106019.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            6681..7157
                     /locus_tag="RZS16_RS14500"
                     /old_locus_tag="RZS16_14495"
     CDS             6681..7157
                     /locus_tag="RZS16_RS14500"
                     /old_locus_tag="RZS16_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664727.1"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA];
                     GO:0006276 - plasmid maintenance [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="WP_000664727.1"
                     /translation="MKERYGTVYKGSQRLIDEESGEVIEVDKLYRKQTSGNFVKAYIVQ
                     LISMLDMIGGKKLKIVNYILDNVHLSNNTMIATTREIAKATGTSLQTVITTLKILEEGN
                     IIKRKTGVLMLNPELLMRGDDQKQKYLLLEFGNFEQEANEKQENALSDYYSFKD"
                     /name="replication/maintenance protein RepL"
     gene            7865..8599
                     /gene="erm(C)"
                     /locus_tag="RZS16_RS14505"
                     /old_locus_tag="RZS16_14500"
     ARG             7866..8596
                     /name="erm(C)"
                     /gene="erm(C)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(C)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8896..9570
                     /locus_tag="RZS16_RS14510"
                     /old_locus_tag="RZS16_14505"
     CDS             8896..9570
                     /locus_tag="RZS16_RS14510"
                     /old_locus_tag="RZS16_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001106019.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(9679..9867)
                     /locus_tag="RZS16_RS14515"
                     /old_locus_tag="RZS16_14510"
     CDS             complement(9679..9867)
                     /locus_tag="RZS16_RS14515"
                     /old_locus_tag="RZS16_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001063224.1"
                     /translation="MNNNEENSVFFGKKKKVSLHLLVDPDMKDEIIKYAQEKDFDNVSQ
                     AGREILKKGLEQIKSNK"
                     /name="hypothetical protein"
     gene            10039..11013
                     /gene="trsA"
                     /locus_tag="RZS16_RS14520"
                     /old_locus_tag="RZS16_14515"
     CDS             10039..11013
                     /gene="trsA"
                     /locus_tag="RZS16_RS14520"
                     /old_locus_tag="RZS16_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein TrsA"
                     /protein_id="WP_000368849.1"
                     /translation="MDNITFRKRIEEYRKRSIEQKKYESKLNYQSRFGVKDDEVSTFNI
                     KGIATDKKENKLVMAEDREDKQKVLLYANKDNDMYYLNSGSTYKEAVQNTFGNETNYEM
                     VDDELFIYNSKNQALTNYDQLDEYHNRQKQLQYNTKLEQERKQRLTDTNKVSENAKEDL
                     ALSLGLTATALKGNINISNVEKVTDNESMVTIENEINGKSEHLISDFKDSFIEKAKEKL
                     TVSPSMRLGFEEFKNASGQIAMGFTEFFGARYDESTLENDPKVVATEKGYSVSVFDKDG
                     NKKDLTSADTFEEAVKLSKEMKHDNSLSRSEIELNQELEKKKI"
                     /name="trsA"
     gene            11030..11347
                     /locus_tag="RZS16_RS14525"
                     /old_locus_tag="RZS16_14520"
     CDS             11030..11347
                     /locus_tag="RZS16_RS14525"
                     /old_locus_tag="RZS16_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CagC family type IV secretion system protein"
                     /protein_id="WP_000591622.1"
                     /translation="MIKKFSLTTVYVAFLSIVLSNITLGAENPGPKIEQGLQQVQTFLT
                     GLIVAVGICAGVWIVLKKLPGIDDPMVKNEMFRGVGMVLAGVAVGAALVWLVPWVYNLF
                     Q"
                     /name="CagC family type IV secretion system protein"
     gene            11407..11814
                     /locus_tag="RZS16_RS14530"
                     /old_locus_tag="RZS16_14525"
     CDS             11407..11814
                     /locus_tag="RZS16_RS14530"
                     /old_locus_tag="RZS16_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000110157.1"
                     /translation="MSVEQEVKDIMLDMLGEEKKVKENIIPRNVDASYKIFLNLNGKEL
                     AIVFVPFLLFLTIAFGVTFLMGLLNLITGFMVFIVGLIFGLTIYGLLTIRPISTKENIR
                     MIDTIKQSQRFSRRQKVYFYKSKEGLGDDDV"
                     /name="hypothetical protein"
     gene            11801..12484
                     /gene="trsD"
                     /locus_tag="RZS16_RS14535"
                     /old_locus_tag="RZS16_14530"
     CDS             11801..12484
                     /gene="trsD"
                     /locus_tag="RZS16_RS14535"
                     /old_locus_tag="RZS16_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrsD/TraD family conjugative transfer protein"
                     /protein_id="WP_000979860.1"
                     /translation="MMMFKKKNKQNKNNEQQFEIINRYIKGDGRNQSIQEDSLIAGFYK
                     DYVVTKDGYISGGLNITGVNTELLTKFEQNDLLEEYSSFISNILYDEPMIKTITEPVNI
                     QNYIKHLYRQVLLDMKNNNNKPTRRGQLIAGRILFLQEKLAKGEMSTKKHYIFFSEKIT
                     ENTVAQLDHAVNRLHEKINLNKEALQQAFSHYGLETRPIYQTEYLNQFYALYDYKGYND
                     YHLSN"
                     /name="trsD"
     gene            12505..14517
                     /locus_tag="RZS16_RS14540"
                     /old_locus_tag="RZS16_14535"
     CDS             12505..14517
                     /locus_tag="RZS16_RS14540"
                     /old_locus_tag="RZS16_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="WP_000874919.1"
                     /translation="MAFLKKKKQEQVTNKIHNESFQKLTEVLDTDSVDSIYPFSWIEKK
                     SHIETGENYIKNLLVVDYPQSVKGAYLSNLLKKNGNIQITKFIRPANIERMIDHLNNSI
                     KNKTAEQMRTTDPKRNATIKREIESSKKQLDKFLDEKTGFMYMYMYITLNGDSYEKIQA
                     LEKDVKRTLTRLRLKTHTPTNAMRESFHTVLPLNRNFLSAFTQQNMDTATAGHFFMFDD
                     SEIIDLTPNTSVFGINKNTDSLVAVDFNNKEKTLNKNMTIIGTSGVGKSTLNMRMILDN
                     IKKSIRQFIIDPEDEFSYITKYYGGTVVNISTSSNIKINPFEIFSEEVFEKEDETDNET
                     TSDVLTENNEHESQIDTLVRSKIGKLKTFFRVLKDEISQTEISVLSSTLRQLYQDKGFK
                     GNAKLSDFKSEDYPTLTELYNKLKDLDPEKYEVLKDLTLIIEDYTMEHGTTTIFDGYTN
                     IKLDNEIVTFNLKPLQTEKDVQSAAYLNIFSFLWDEITKDRTTETVLMTDELHFLATNE
                     YSLDFYYQAYKRIRKYGGGAIASTQQIKDILRTSQEIGSAIIENSHTKFFFGMDNVGVD
                     DVVDKLGLKFSDQEISHLTKKKKGEALLLYGTQRAFIRIDLDREETRLWNKELYETIYE
                     EPADVEPNYVEQLGLTDIDLAELEEELRQAEMIYE"
                     /name="DUF87 domain-containing protein"
     gene            14529..15809
                     /locus_tag="RZS16_RS14545"
                     /old_locus_tag="RZS16_14540"
     CDS             14529..15809
                     /locus_tag="RZS16_RS14545"
                     /old_locus_tag="RZS16_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein"
                     /protein_id="WP_000702361.1"
                     /translation="MKIRNFNEGTLVGKHNHLEYIINVDLCHISDIDEIRYDLTEPNEL
                     FFEVKDLQKEGDYFHIIYNTDNEYNSFLSAKKESKALKLSLMDYVLKVDPLKDNITVMH
                     PANLFFKNIEDIKIGFKGHEYLPKPKINNLEQYKLLIMSTLSQYTFDKYYRNKFEVLSK
                     EKDDFFHKVNNAETFEKLKEIVRHELNQVQTDYLLNEEKRKRETRKKYIRNLILGFVGI
                     AIVISLISFMIINGKQQELDSKIAQADKQEQRSKVYENLYNGNVDQAVKGMKRDDSFNK
                     KDIEKTLKKEKKYEELIELSSKNTPYVIEQLYKEGKQNKIRELAFNFENNDTLSLEKKI
                     LDKDGTAFSVGSTGKYEEQSKRLALASAKEGYVESAKDINKKLKDNEVEEEINKAEIKQ
                     LKEEKDSTKDKDKKKEIQKDIEELEKK"
                     /name="membrane protein"
     gene            15827..16903
                     /locus_tag="RZS16_RS14550"
                     /old_locus_tag="RZS16_14545"
     CDS             15827..16903
                     /locus_tag="RZS16_RS14550"
                     /old_locus_tag="RZS16_14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="WP_000269385.1"
                     /translation="MWSAIAKGITMLMKKKALSKILKPVIAIVIGFFLLIFIMIAYLVG
                     SFTKEINESGEQKMKEAESTATGACTGGSVDGSGISAFEKNAKGGALEGKGKDMVKIAK
                     KNKIPPKLFIAIVASESEWGRGANATKQKNPLSIMGAGPLQVYPSIEEGLDKGAKNLYD
                     LYISEGLTTPEKIGPKYAPVGASNDPDDLNSNWVPTVKKIMKSFGGKEAKCSTESSGGG
                     SDGKGFDFKGEFPKPDKSKYNGQSYPWGQCTWYVHQRRKEIGKPVPLTWGNGGDWGDNA
                     KAQGWEVGSKPKAGAGASVKPGNFGAPPPYGHIMFVEKVKKDGGIVVSEANVKGLGVIS
                     SREFSKAETQRMQFIYDK"
                     /name="CHAP domain-containing protein"
     gene            16913..17398
                     /gene="trsH"
                     /locus_tag="RZS16_RS14555"
                     /old_locus_tag="RZS16_14550"
     CDS             16913..17398
                     /gene="trsH"
                     /locus_tag="RZS16_RS14555"
                     /old_locus_tag="RZS16_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrsH/TraH family protein"
                     /protein_id="WP_000735569.1"
                     /translation="MKKLLTIVILFTLVLAGCGQNQSEKNSEKHNEEKTVDTTEERNDM
                     IKGLIEYGYENDDYKGYKHMKDILSEKLQKQAELQNQSAQTKGVKKETKDIKLYQDVDN
                     DDELIYSIKLSITNKKEKNSDYSMRYGKIELTEEEGKQKIDNVEELTQRNLVSMNQE"
                     /name="trsH"
     gene            17414..19516
                     /gene="topB"
                     /locus_tag="RZS16_RS14560"
                     /old_locus_tag="RZS16_14555"
     CDS             17414..19516
                     /gene="topB"
                     /locus_tag="RZS16_RS14560"
                     /old_locus_tag="RZS16_14555"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001094110.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003917 - DNA topoisomerase type I (single strand cut,
                     ATP-independent) activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="WP_001094109.1"
                     /translation="MNTLILCEKPSQAMDLSTVFAKKKKQNGYMEISDEQLNVSGFLTW
                     AVGHLVELKEPQEYDEKYKNFSTYPILLEKDDFQFKVSDKTKDQFNNIKKIFKENKIDE
                     VIIATDPAREGENIAYKILNQLKVTDKVTIKRLWLTSKVESSIRKAFKNILPKEKTYGF
                     YKEGRARELSDWLVGINLSRHFTKISRELGNDGVIHIGRVSSPTLNMVYNRENNIKGFK
                     GKKFYKVSATINKDEQEVKTELKNKFDSEDELHEFLFENDITDLTQKGLVTDIEKEIGY
                     TMPPKFYDLSALQEDMNDKYKISAKRTLEIAQTLYEKKLITYPRTDSRYITEDEKEMLL
                     ENIDYLKEITKINLNNELTNNSLINPSKIEDHYAILITGNDFNKVDLKEEEINVYKSIL
                     QNVAMNFMDKEQYETTTIEIAVKKLMFEVKGKIIQDNGFKALLNKQKTSEETIPNFEKN
                     EEVDIELDLLEKETTPPKRYTEKTLLKAMANPIETLEDEGLKSTLKEVKGLGTPATRAD
                     IIENLKKNKYIQVQKNKIYITKNGILACLLLEGHLLSKPDLTGQWEKYLNGISKGEKDD
                     DSFINTINEMIKKTINEEVKNKESIQKVAKEKVSTNNIAKCPACDNGYLIDRKGFYGCT
                     EYNNGCEFTIPKKLLEKSIPPTVVKALCESKTTKKLKGFKSKKSGKSFDCKLILTKENK
                     LQFSFD"
                     /name="topB"
     gene            19532..19996
                     /locus_tag="RZS16_RS14565"
                     /old_locus_tag="RZS16_14560"
     CDS             19532..19996
                     /locus_tag="RZS16_RS14565"
                     /old_locus_tag="RZS16_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000715274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000715273.1"
                     /translation="MKKGIFILTGIIWLVLIYLAQILAYALNTLSNTSNKQKIFSDISQ
                     LFIPPAKHPISTIIGFVSDKNTVFFVIGVIATIICIYILIKQLFESKDGNEKNQDYKIA
                     KHGSHGSAKFAEDSELFSEGHYKKMKENDITNYVYNSLDKSLIEERSDKE"
                     /name="hypothetical protein"
     gene            19993..21633
                     /locus_tag="RZS16_RS14570"
                     /old_locus_tag="RZS16_14565"
     CDS             19993..21633
                     /locus_tag="RZS16_RS14570"
                     /old_locus_tag="RZS16_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="WP_000209436.1"
                     /translation="MTTLLGELESKATSINKKNLVIQDFDTKCPNRNIFVVGGPGSYKS
                     AGYVIPNVIVKNQQSIVVTDPSGEVYEKTSNIKRMQGFDVRVVNFKNFLASDRQNFFDY
                     IDKDSDCSIVAELIIKSAGDSKINKDVWYKASVGLLNSLLLYAKYEFEPEKRTIGNIIK
                     FIQNNKPNQDEEGSVELDKRFNELSKDHPARESYEFGFAVSEGRTRASIILTFVADLRN
                     YIDNEIRSYTSDSDFDLRDVGLRKTIIYVMLPVLGNTVQSLSSLFFSQMFQQLYRLGDE
                     NGARLPVPVDFLLDEWPNIGAIPDYEETLATCRKYGISITTIVQSISQAVDKYNKDKAN
                     AIIGNHAVILCLGNVNNDTAKYIKEELGNATVEFETSSEGSSSGKDSRSKSSNKNVSYT
                     GRALLNEDEISNMQQDKAILITKNRNPKIIKKLAYFKMFPNLTETYIAPQNEYKRKKNQ
                     SMIDKHNRLREEWDKKQEKNKQQKLEEYKEEQRQKELEKEQQPQEEQQNEKVKESKDKN
                     DQEDKKDEQQKINDSKKAFYEKLKQKQAK"
                     /name="VirD4-like conjugal transfer protein, CD1115 family"
     gene            21711..22628
                     /locus_tag="RZS16_RS14575"
                     /old_locus_tag="RZS16_14570"
     CDS             21711..22628
                     /locus_tag="RZS16_RS14575"
                     /old_locus_tag="RZS16_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL family protein"
                     /protein_id="WP_000383804.1"
                     /translation="MDWIKDAIKELTEGIADGMMNFIFQFLYTLFYEPLKFFIWLLDKI
                     LIDPNSISSDYISNASVLVNSLITSIAICVFAFKMVQVMKQNAEGNAESPGYYVAQLLP
                     SSLLVAVLPWLVDIMTKLSYSATRAFLDVGQKSYLETIKEWSSLKKGQDGFKEMLGSMG
                     TMAGSQIMFILFILLILVFTVVFIFQFVSRIADLVIMKVVAPLVAVSLLADENNYIGVW
                     WRELLAISIQLPLQVFTFFGGINLFFGAKLDVGTLLLGIGFFIITVKSPSFIRSMVYST
                     GSGRMATGMAGSGAKLLVRKMLSK"
                     /name="conjugal transfer protein TrbL family protein"
     gene            22645..23037
                     /locus_tag="RZS16_RS14580"
                     /old_locus_tag="RZS16_14575"
     CDS             22645..23037
                     /locus_tag="RZS16_RS14580"
                     /old_locus_tag="RZS16_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000608970.1"
                     /translation="MINKVIYSGRIATDLKLRKSKNEKSYVFFNIAVPRQFDNDRTDFI
                     NCVVWGKQAESLVDYQSKGNLIIIEGSTETYKKDNINMSRCLVEKTIFLESKKENKKHD
                     VSEDDAISPAEDSGNDKSISDDDLPF"
                     /name="single-stranded DNA-binding protein"
     gene            23094..23261
                     /locus_tag="RZS16_RS14585"
                     /old_locus_tag="RZS16_14580"
     CDS             23094..23261
                     /locus_tag="RZS16_RS14585"
                     /old_locus_tag="RZS16_14580"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000869301.1"
                     /translation="MKVTNTIRFEEEKKNLIDNVVNTLEEYKDVIDSELRTIRNTNHLV
                     MRNNLVLLQS"
                     /name="hypothetical protein"
     gene            23299..23973
                     /locus_tag="RZS16_RS14590"
                     /old_locus_tag="RZS16_14585"
     CDS             23299..23973
                     /locus_tag="RZS16_RS14590"
                     /old_locus_tag="RZS16_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105950.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAIAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            24103..24717
                     /locus_tag="RZS16_RS14595"
                     /old_locus_tag="RZS16_14590"
     CDS             24103..24717
                     /locus_tag="RZS16_RS14595"
                     /old_locus_tag="RZS16_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000527296.1"
                     /translation="MGNLDFDHEGYRKLLPLKDFKHFIKHSDSKTRNHFIGMAFNNKTD
                     VFSRNFSNKMINIFPKNEFYIHIQQFPENDSPSYMVYNTDITAFIQFRLVGRSENKYLE
                     NIIRDYGVLIEVEALHSFKKGMGAMLVSQLEKLSDKLFIPIYLYDTNLKDELYYQDLGF
                     FDTTKKGNHGEPLLVYKPKNLETNKKEKPIKSLFKKVFNIN"
                     /name="hypothetical protein"
     gene            24786..26057
                     /locus_tag="RZS16_RS14600"
                     /old_locus_tag="RZS16_14595"
     CDS             24786..26057
                     /locus_tag="RZS16_RS14600"
                     /old_locus_tag="RZS16_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000386736.1"
                     /translation="MDYTNQKRKYIIFGIVLAITLLIVGIAYYLISLNNAKGQVKEFEK
                     LVQHNDYNSIAKKLSNKEETLSENDAKNFVLFVKSKENQEQYNEQIQKIKSNIDKNKDN
                     NTVYGSITDQYGNNLITIKKNGKTFFFIDKLEFKPKLTSVYVKEFNNTGIYKYQQENAK
                     KVIAESNQTTELGKFFIGKYSIKTDKTIEDSIHNGTLTGKIDIDLSNRGNNNKIYADED
                     FNQSWFKVKLNNDSLLEKNSYKLLIDDKDVDYNSKKTYGKYYNPTELSVYAIGKLEGKE
                     FKTNRINIRRNYDNKPQNLKLSFKESQIRDYESKSKKVKEKAKSYIKEYTKELNKAYKK
                     KDYKYISDYVKNNSQLEKQLKKQVKSKSKVKFKDVKINNVKRDKNKIYIELSKTNNGNV
                     FQTKYTLDYDNVSNEFLVEDSHDN"
                     /name="hypothetical protein"
     gene            complement(26099..26515)
                     /locus_tag="RZS16_RS14605"
                     /old_locus_tag="RZS16_14600"
     CDS             complement(26099..26515)
                     /locus_tag="RZS16_RS14605"
                     /old_locus_tag="RZS16_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YolD-like family protein"
                     /protein_id="WP_000691761.1"
                     /translation="MKIINPNMPEPYKYETDYRNIPREYLNPHIPKGRGIVKWNAFKTI
                     PQQYEILEQHIEDQNKINMPLLSDDQLQEINEKVSSKISKNILTDLDYWKDGYIYSIQC
                     YINKIDEFNGFMIITNSNSNNKLKIPLSSIVSVQ"
                     /name="YolD-like family protein"
     gene            26810..27367
                     /locus_tag="RZS16_RS14610"
                     /old_locus_tag="RZS16_14605"
     CDS             26810..27367
                     /locus_tag="RZS16_RS14610"
                     /old_locus_tag="RZS16_14605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273859.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001273859.1"
                     /translation="MANIGYARVSTRDQSLDLQIDALSNFGCEKIFSEKVSGRKVNRTE
                     LDKCLDYLREGDTLVIYKLDRLGRTTKQLIDLAQWLENNNIELQIIDMNINTKDPMGKM
                     FFTMMSAFAELEANLLSERTKKGLESARARGNMGGRKAMPQEKKEYIKHLYDTKEYTGQ
                     EIAKKTNVSRDTVYRILREFKK"
                     /name="recombinase family protein"
     gene            27649..28428
                     /locus_tag="RZS16_RS14615"
                     /old_locus_tag="RZS16_14610"
     CDS             27649..28428
                     /locus_tag="RZS16_RS14615"
                     /old_locus_tag="RZS16_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000454413.1"
                     /translation="MEVVRLNQNLFNKLRGNEISSNKNGSRPYYYSFKRNNNRVCIPFR
                     TNAQKVPNKYKINLGGEQPDKPNSAIDLTKSIVISNDEYLNNRSKAKIPQNVNNFLKQQ
                     APAIEQKYDTMSNDYIKAKASLSKIPLVKYSTMQYFHKELNIQDSIDNQQTKNAINELI
                     SNGKSNKYNKLQSSLPNEKLNLLDDYETLYEFKSLTDYPAKINSNDIDNPFLEVEKNNK
                     HFTLSALTIKNEPEKHVKDFLNYDIENEKNKDIDLDL"
                     /name="hypothetical protein"
     gene            28562..30178
                     /locus_tag="RZS16_RS14620"
                     /old_locus_tag="RZS16_14615"
     CDS             28562..30178
                     /locus_tag="RZS16_RS14620"
                     /old_locus_tag="RZS16_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001212937.1"
                     /translation="MRFTPRGILNNTDYELNSEFYYVPASDKQMNDQRDMTNKSIVGNL
                     VYRNNFYNEVYTQPVYDLDDSNEKYQTPHIISIDDSEFDYNLTNLDDYFTKDTANKGYE
                     KLVNAIKSEEITYFDSDINEVDDFTQQDEYSNDWYTNTFVDLVLSMKGYSYHVEPNRES
                     VIEDSHIITENDITYNVSYNPEKHHLYINDFPAIPIEENDNIRLLNDNLTQDMEKTYDN
                     INYNFSYNDFKTLEDDSYIYIDLTDYKDNEGKFVKNLIEDIPPNEIIKDRLKQNINLFD
                     ERANYNALAVYRRDLEDFSDRNNLDSLDKVKDLKTFYDTEINIKGLNINNDIEKKALNN
                     QLAFNLYNEPLNNMFRDNNVLYEVYEKEIYDEKIPLSIEDRKEVKTYLDDARNNFSNNF
                     YEYTTNKSSILAENSLTVLDKAKYDLEFAPVSNHLYKERENFYEGMKQATLPLHNITKE
                     QYKERENDIEIIGHFKNYINTELHGTKSSEFKPNFVNDSLENETNSIAFEDIINGSEET
                     HSNIINSIKNELKQERDNLEM"
                     /name="hypothetical protein"
     gene            30189..30377
                     /locus_tag="RZS16_RS14625"
                     /old_locus_tag="RZS16_14620"
     CDS             30189..30377
                     /locus_tag="RZS16_RS14625"
                     /old_locus_tag="RZS16_14620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000921494.1"
                     /translation="MLKTYTEIIGSELPIYITKSETSELLFSEELDKNLKYEVAGYYLY
                     NAKKDLYKELYKPISEV"
                     /name="hypothetical protein"
     gene            30381..32105
                     /locus_tag="RZS16_RS14630"
                     /old_locus_tag="RZS16_14625"
     CDS             30381..32105
                     /locus_tag="RZS16_RS14630"
                     /old_locus_tag="RZS16_14625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC family protein"
                     /protein_id="WP_000331763.1"
                     /translation="MAYSKGNYKKKKIDSIIEELNNKLDDFKNNDKTYKEFLDTTAKFH
                     NYSINNIILIAGQNPEATAVAGYKAWKNKFDRQVQKGAKSMNIIAPIVQKRNVEIKDDN
                     GNIVRDNNGNPKTERKPVITGYRAHNVFDVADTKGKPLITAKDLIKTEFENSNDYKDLY
                     NEFKDYINEELTPSVEEKHFLDDPTLSNGAKGYYSPKSDEIVISDDLSYDMRFKTLIHE
                     YAHSQLHNNDIGKTQISEHSRSLKEIEAESSAYVVANYYGLDTSDYSLGYLSGWGHNIS
                     DDELKAHIKNIHSFAKTTIEEINSLPEFSQYIDKKLESEMNKDVYKDLSTMIDTNLKNG
                     FDKITIIKGNLVNDYGLNEISENSYENDDFKVNIDYKGFNTNNSQDQAKIELINKHDDS
                     LNRDYNFTQTYNRNVINNTTTIFVQDDDNEDKNKKYIHERDIDGNILEEKHKLSPQDEI
                     VSFENFVNKSVEENGLKDTLRQFVSNGVLMGYELNVDNIDNTNETYFSMNKNQQNGQRS
                     NMTAKLEHDTNENVYIDFKIKNSAGIKNISYTESNEEFNKDEQNKEIENKQEEEIDI"
                     /name="ArdC family protein"
     gene            complement(32146..32862)
                     /locus_tag="RZS16_RS14635"
                     /old_locus_tag="RZS16_14630"
     CDS             complement(32146..32862)
                     /locus_tag="RZS16_RS14635"
                     /old_locus_tag="RZS16_14630"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015445997.1"
                     /translation="MLENKHEGMEDSLKIDYYTNKLEVFRNAENILEDYYDVQIKELFT
                     DDEDYKAFNEVTDIKEKQQLIDFKTYHGTENTIEMLETGNFIPKYSDEDRKYITEQVKL
                     LQEKEFKPNKNQHDKFVFGAIQKKLLSEYDFDYSDNNDLKHLYQESNEVGDEISKDNIE
                     EFYEGNDILVDKETYNNYNRKQQAYGLINAGLDSMIFNFNEIFRERMPKYINHQYKGKN
                     HSKQRHELKNKRGMHL"
                     /name="hypothetical protein"
     gene            complement(33233..34144)
                     /locus_tag="RZS16_RS14640"
                     /old_locus_tag="RZS16_14635"
     CDS             complement(33233..34144)
                     /locus_tag="RZS16_RS14640"
                     /old_locus_tag="RZS16_14635"
                     /inference="COORDINATES: protein motif:HMM:NF015354.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_011443608.1"
                     /translation="MAMYHFQNKFVSKANGQSATAKSAYNSASRIKDFKENEFKDYSNK
                     QCDYSEILLPNNADDKFKDREYLWNKVHDVENRKNSQVAREIIIGLPNEFDPNSNIELA
                     KEFAESLSNEGMIVDLNIHKINEENPHAHLLCTLRGLDKNNEFEPKRKGNDYIRDWNTK
                     EKHNEWRKRWENVQNKHLEKNGFSVRVSADSYKNQNIDLEPTKKEGWKARKFEDETGKK
                     SSISKHNESIKKRNQQKIDKMFNEVDDMKSHKLNAFSYMNKSDSTTLKNMAKDLKIYVT
                     PINMYKENERLYDLKQKNFINH"
                     /name="MobA/MobL family protein"
     gene            34348..34620
                     /locus_tag="RZS16_RS14645"
                     /old_locus_tag="RZS16_14640"
     CDS             34348..34620
                     /locus_tag="RZS16_RS14645"
                     /old_locus_tag="RZS16_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000763628.1"
                     /translation="MADIQKMLEQKEKLQEKIKEEKKKEYEKFGRWFFNKFKVNRSADA
                     KKIINKNLLNIEDTKEHNLERNEIIEETKNSNEENKEINEINHNI"
                     /name="hypothetical protein"
     gene            34724..34957
                     /locus_tag="RZS16_RS14650"
                     /old_locus_tag="RZS16_14645"
     CDS             34724..34957
                     /locus_tag="RZS16_RS14650"
                     /old_locus_tag="RZS16_14645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000602211.1"
                     /translation="MILLSTAGENAVHINPIFRFFLYFIMCVPMTVALCTIFLKFISIF
                     ILPWKVCLYIGIALGIIVTIFLLVITIGIEMT"
                     /name="hypothetical protein"
     gene            35220..36260
                     /locus_tag="RZS16_RS14655"
                     /old_locus_tag="RZS16_14650"
     CDS             35220..36260
                     /locus_tag="RZS16_RS14655"
                     /old_locus_tag="RZS16_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000073389.1"
                     /translation="MSNVYVMALDFGNGFVKGKINDEKFVIPSRIGRKTNENNQLKGFV
                     DNKLDVSEFIINGNNDEVLLFGNDLDKTTNTGKDTASTNDRYDIKSFKDLVECSIGLLA
                     REVPEEVVNVVIATGMPSNEIGTDKQAKFEKLLNKSRLIEIDGIAKTINVKGVKIVAQP
                     MGTLLDLNMENGKVFKAFTEGKYSVLDFGSGTTIIDTYQNMKRVEEESFVINKGTIDFY
                     KRIASHVSKKSEGASITPRMIEKGLEYKQCKLNQKTVIDFKDEFYKEQDSLIEEVMSNF
                     EITVGNINSIDRIIVTGGGANIHFDSLSHYYSDVFEKADDSQFSNVRGYEKLGELLKNK
                     VEQESK"
                     /name="hypothetical protein"
     gene            36263..36592
                     /locus_tag="RZS16_RS14660"
                     /old_locus_tag="RZS16_14655"
     CDS             36263..36592
                     /locus_tag="RZS16_RS14660"
                     /old_locus_tag="RZS16_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WP_000358311.1"
                     /translation="MDKKETKHLLKIKKEDYPQIFDFLENVPRGTKTAHIREALRRYIE
                     EIGENPPIPSKEHTAPLKEHTEPIKRNKESFKDAMERKDQLKQAEMPKIEEKDEEMVDI
                     SIDDL"
                     /name="recombinase"
     gene            complement(36596..36856)
                     /locus_tag="RZS16_RS14665"
                     /old_locus_tag="RZS16_14660"
     CDS             complement(36596..36856)
                     /locus_tag="RZS16_RS14665"
                     /old_locus_tag="RZS16_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008213.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_001008213.1"
                     /translation="MNEYRIQKLYRYICLEFKNQRQLIGKRQEEVAFDLSVTAGHLSRI
                     ENGKKPRIALHTFLVMSEYYGVDFHKVVKNAEEKMELDEGI"
                     /name="helix-turn-helix transcriptional regulator"
     ARG             2163..5236
                     /name="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene_name="antibiotic-resistant isoleucyl-tRNA synthetase
                     (ileS)"
                     /tool="rgi"
                     /drug_class="mupirocin-like antibiotic"
                     /identity="99.61"
                     /coverage="100.0"
     ARG             7866..8599
                     /name="ErmC"
                     /gene="ErmC"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="99.18"
                     /coverage="100.0"
     Typing          102..1060
                     /name="rep_cluster_1142"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6682..7167
                     /name="rep_cluster_1947"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.591"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(32150..33255)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.393"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(33252..34144)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.658"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12506..14514
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="97.91"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19994..21606
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="97.222"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 aagttatata taacggataa cattatataa ccttattcat cacttgtaaa taacgatatt
       61 acttaaactc cttaaatata catttaaagg agtttttatc atgtctaaac aattttttac
      121 agtagaagaa aattataaag aacgctttta ccaattacct aaagtatttt ttactaatcc
      181 taattataaa gatttatcga atgacgctaa aattgcttac gcaatattga gagatcgttt
      241 acaattatct attaaaaata actggataga tacagaaggt aacatatatt tcatttatac
      301 agttgctgat ttagaagtga tattaaattg tgggaacaaa aaaatcacta aaattaaaaa
      361 agaattagaa aatgtagatt tactaatcca aaaaaggcag ggtttaaaca aaccaaatct
      421 actttattta ttaaaaccag ccataactaa aaatgatatt tatgaaatag ataaggctga
      481 aaatgaagtt gaggccttac aagacaagga agtgtcaaaa ggacacgtcc agaaatgtca
      541 aaaggacacg tctagaaatg tcaaaaggac acgtctagaa atgtcaaaag gacacacaaa
      601 tgatactgat tttattgata ctgattttat tgatactgaa agtaatgata tgaataatat
      661 gaatgataca aatcaacatt caaatcattc aaatcacttt tcaaatattc atgataaaga
      721 atctcttaaa tatatagaac ttcaagaact ccccgaatta attaaaagtt atattaataa
      781 tttcagctat gaagaagtta aaagtattaa atctgttatt ttaaaagcta aaaaatcatt
      841 taataacaaa tacgatactt tctatatgtt agaagatata gatgaagaat tactattggt
      901 tttaaaacga tttaaaggtt atcttgttaa aaaacaagaa aaagtagcta atatggaagg
      961 ttatttaatg agaagtatca ttgctgaact tgaagaaatg cactcaacta ttatgagaag
     1021 aaaaaatatg gaaaacaatc cattatctct atttaattag tttttgaagt taaattttca
     1081 aaaaaaagag attatacacc taaaaaggtg tataatcttt acggttctgt tgcaaagttg
     1141 aatttatagt ataattttaa caaaaaggag tcttctgtat gaactatttc agatataaac
     1201 aatttaacaa ggatgttatc actgtagccg ttggctacta tctaagatat gcattgagct
     1261 atcgtgatat atctgaaata ttaagagaac gtggtgtaaa cgttcatcat tcaacgatct
     1321 accgttgggt tcaagaatat gccccaattt tatatcaaat ttggaagaaa aagcataaaa
     1381 aagcttatta caaatggcgt attgatgaga cgtatatcaa aataaaagga aaatggagct
     1441 atttatatcg tgccattgat acagagggac atacattaga tatttggttg cgtaagcaac
     1501 gagataatca ttcagcatat gcgtttatca aacgtctcat taaacaattt ggtaagcctc
     1561 aaaaggtagt tacagatcag gcaccttcaa cgaaggcagc aatggctaaa ataattaaag
     1621 cttttaaact taaacctgac tgtcattgta catcgaaata tctgaataac ctcattgagc
     1681 aagatcaccg tcatattaaa gtaagaaaga caagatatca aagtatcaat acggcaaaga
     1741 atactttaaa aggtattgaa tgtatttacg ctctatataa aaagaaccgt aggtctcttc
     1801 agatctacgg attttcccca tgccacgaaa ttagcatcat gctagcaagt taaacgaaca
     1861 ctgacatgat atattagtga ttagctatat tttttacttt gcaacagaac caaatttata
     1921 atagtatagt ttcaacatgg gatgtttata aaaataacga atatagcaaa gacctttcaa
     1981 gagaattaaa atttaaatta tatactacta atgatataat ttgcagtagt ttgtattata
     2041 actttacttt atccaatata tctttctatg gagacatgaa aggaaatgaa tttcatgaaa
     2101 attcaccaag actaatagta aaaataacga aataagtgat actctaggag gctgaaaagt
     2161 tttgacaaag aaatatttaa acacccagaa tgaaatatca gcattttgga atactcaaaa
     2221 gatatttaaa aaatcaattg acaatagaaa aggacaggaa agttttgttt tttatgacgg
     2281 ccccccaact gcaaatggcc ttcctcatgc tggccatgtt cttggaagag taatcaagga
     2341 tttagttgca agattaaaaa ctatgcaagg tttttatgta gaaagaaaag caggatggga
     2401 tacccatggc ttaccagttg aattagaggt tgaaaaaaaa attggaatta aaggaaaaca
     2461 agacattgaa aagtatggaa tagaaaattt tataaatgaa tgtaaaaaaa gtgtatttaa
     2521 ttatgaaaaa gaatggcggg atttttctaa agatttagga tactgggttg acatggactc
     2581 cccctatata actcttgaga ataattatat tgaaagtgta tggaatatat tatctacatt
     2641 ccataaaaaa ggactattat ataagggaca taaggtgact ccttattgta cacatgatca
     2701 aaccgcttta agttctcatg aagtagcgca aggctataaa aacgttaaag atttatcagc
     2761 tgttgttaaa tttcaactta caaatagtaa agatacttat ttcttaagtt ggactaccac
     2821 tccctggact ttgcctgcaa atgtagcatt agctataaat aaagatctta attattcaaa
     2881 aattcgggta gaaaatgagt attatatctt agctacagat ctaattaatt ctataataac
     2941 tgaaaaatac gaaattattg ataccttttc aggaagtaat ttaattaatt taaaatacat
     3001 tcctcctttt gaaagcgacg gtttagttaa tgcatattac gttgttgatg gagaatttgt
     3061 tactaactca gaaggaactg gtattgttca tatagcacca gctcatgggg aagatgacta
     3121 ccaattggtt ttagagcgtg atttggattt cttaaatgtt ataacaagag aaggagtata
     3181 taatgatagg ttccctgaat tagttggtaa taaagctaaa aatagtgata tagaaatcat
     3241 aaaattatta tccaaaaaac aacttttata taaaaaacaa aaatatgagc ataattatcc
     3301 tcattgttgg agatgtggta atcctttgat atattatgcg atggaaggtt ggtttattaa
     3361 aacaactaat tttaagaatg aaattattaa caataataat aatatagagt ggtttccttc
     3421 tcatattaag gaagggagaa tgggaaattt cttagaaaat atggttgatt ggaacattgg
     3481 tagaaataga tattggggaa caccattaaa tgtatggatt tgcaatgatt gtaatcacga
     3541 atacgcacca agtagtatta aggatttaca aaataattcc atcaataaaa ttgatgaaga
     3601 tattgagttg catagacctt atgttgataa tatcactctt agttgcccta agtgtaatgg
     3661 gaaaatgtct cgagtagaag aagtaatcga tgtttggttt gatagcggct ctatgccgtt
     3721 tgctcagcat cattatcctt ttgataacca gaaaattttt aatcaacact ttccagctga
     3781 ttttattgca gaaggagttg atcaaacgag aggctggttt tacagtttac tagtaatttc
     3841 tactattcta aaaggaaaat cttcttataa acgtgcttta tctttaggac atattctaga
     3901 cagtaatggt aaaaaaatgt ctaaaagtaa aggaaacgtt attaatccaa ctgaattaat
     3961 taataagtac ggagccgatt ctttaagatg ggccttaatt tcggatagtg ctccatggaa
     4021 taacaaaaga ttctcagaaa atatagtagc tcagaccaaa tcgaaattta tagatacgct
     4081 tgataatatt tataaatttt ataatatgta taataaaata gatcactata atcctaataa
     4141 tgaaattaca aaaagtagaa atacattaga taattgggct ctttctcgct taaacacctt
     4201 aataaaagaa agtaatattt atgtaaataa ttacgatttc acttccgcag ccagattaat
     4261 taacgaatat accaatacaa taagtaattg gtatattcgg agatcgagag gacgattttg
     4321 ggaacaagga atttctaacg ataaaaaaga tgcgtacaat acgctttatg aaattttaac
     4381 aactttatca agactagtgg ctccatttgt tccatttata tctgaaaaaa tccattataa
     4441 tttgactgga aaaagtgtgc atttacaaga ttatccacaa tataaagaaa gttttattaa
     4501 tcaagcattg gaagatgaaa tgcataccgt tataaaaatt gtagaattat ctagacaggc
     4561 tcgcaaaaat gcagatttaa aaattaagca acctttatcg aaaatggtga ttaaacctaa
     4621 tagtcaatta aacttaagtt ttttacctaa ttactattca ataataaaag acgaattaaa
     4681 tataaaaaac attgaattaa ctgataatat taatgactat attacctatg agcttaaatt
     4741 gaatttttct tctgtgggac caaaactagg gaacaaaacg aaaaatattc aaacattgat
     4801 agactcccta tcagagtatg ataaaaaaag tttaattgag tctaataact tcaaaagttt
     4861 atcttctgat gctgagttaa ctaaggatga ttttataatt aaaaccttac ctaaggatag
     4921 ttatcaactc agtgaagata atgactgcgt tatattatta gataaaaatt tatctcctga
     4981 attaattcgc gaaggacatg ctagagagct cattagatta attcaacaat taagaaaaaa
     5041 gaaaaattta ccaataaatc aacgtattga tatttatatc ggtgtaactg gggaattatt
     5101 agaatcaata aaaaccaata aaaatatgtt taaagaaaat ttgctgatta aaaatataca
     5161 cttaaatgtt atagatgaat atgaaaatac tattcatttt aataataaag aaataaaaat
     5221 ttccttatta tattaaacaa acatggccac tctattttag tagagtggcc atgagttatc
     5281 aaagccaagc aaaaggtgat aaactatgta taattttgat tattctaaat taccaattaa
     5341 aaatattcaa aaaatatttc ctattgcagg gggatatgtg aatctatctt tttcagttga
     5401 tgcttccaac aaaaaatatt ttttaaagct acaacctaat actaaatcaa atttttttga
     5461 ttatgagtta tccagtttaa aagaattaac tgataaaaat attcctgttc ctcaaattat
     5521 taataaagga gaattagaca ataattcttt tttactgtta gagttcattg aaaatggcca
     5581 tgcttatcct gaaagctata gaaaactagg taaaatagtt gcaaacatgc ataaaaatat
     5641 aaattcacta aatctatttg gctttagtca taatttcggt tctgttgcaa agttgaattt
     5701 atagtataat tttaacaaaa aggagtcttc tgtatgaact atttcagata taaacaattt
     5761 aacaaggatg ttatcactgt agccgttggc tactatctaa gatatgcatt gagttatcgt
     5821 gatatatctg aaatattaag gggacgtggt gtaaacgttc atcattcaac ggtctaccgt
     5881 tgggttcaag aatatgcccc aattttatat caaatttgga agaaaaagca taaaaaagct
     5941 tattacaaat ggcgtattga tgagacgtac atcaaaataa aaggaaaatg gagctattta
     6001 tatcgtgcca ttgatgcaga gggacataca ttagatattt ggttgcgtaa gcaacgagat
     6061 aatcattcag catatgcgtt tattaaacgt ctcattaaac aatttggtaa acctcaaaag
     6121 gtaattacag atcaggcacc ttcaacgaag gtagcaatgg ctaaagtaat taaagctttt
     6181 aaacttaaac ctgactgcca ttgtacatcg aaatatctga ataacctcat tgagcaagat
     6241 caccgtcata ttaaagtaag aaagacaagg tatcaaagta tcaatacagc aaagaatact
     6301 ttaaaaggta ttgaatgtat ttacgctcta tataaaaaga accgcaggtc tcttcagatc
     6361 tacggatttt cgccatgcca cgaaattagc atcatgctag caagttaagc gaacactgac
     6421 atgataaatt agtggttagc tatatttttt actttgcaac agaaccttag ataaccccct
     6481 gatatgctcc gacgctttat atagaaaaga agattcaact aggtaaaatc ttaatatagg
     6541 ttgagatgat aaggtttata aggaatttgt ttgttctaat ttttcactca ttttgttcta
     6601 atttctttta acaaatgttc ttttttttta gaacagttat gatatagtta gaatagttta
     6661 aaataaggag tgagaaaaag atgaaagaaa gatatggaac agtctataaa ggctctcaga
     6721 ggctcataga cgaagaaagt ggagaagtca tagaggtaga caagttatac cgtaaacaaa
     6781 cgtctggtaa cttcgtaaag gcatatatag tgcaattaat aagtatgtta gatatgattg
     6841 gcggaaaaaa acttaaaatc gttaactata tcctagataa tgtccactta agtaacaata
     6901 caatgatagc tacaacaaga gaaatagcaa aagctacagg aacaagtcta caaacagtaa
     6961 taacaacact taaaatctta gaagaaggaa atattataaa aagaaaaact ggagtattaa
     7021 tgttaaaccc tgaactacta atgagaggcg acgaccaaaa acaaaaatac ctcttactcg
     7081 aatttgggaa ctttgagcaa gaggcaaatg aaaaacaaga aaatgcatta tctgattatt
     7141 attctttcaa ggactagtat aacataaaat cgtctacaaa tagacaaaaa acctgcacgc
     7201 ttaatgtaga tcaaaagctt aacgcaaatg aaatagattg acctcccaat aacaccacgt
     7261 agttattggg aggtcaatct atgaaatgcg attaagcttt ttctaattca cataagcgtg
     7321 caggtttaaa gtacataaaa aatataatga aaaaaagcat cattatacta acgttatacc
     7381 aacattatac tctcattata ctaattgctt attccaattt cctattggtt ggaaccaaca
     7441 ggcgttagtg tgttgttgag ttggtacttt catgggatta atcccatgaa acccccaacc
     7501 aactcgccaa agctttggct aacacacacg ccattccaac caatagtttt ctcggcataa
     7561 agccatgctc tgacgcttaa atgcactaat gccttaaaaa aacattaaag tctaacacac
     7621 tagacttatt tacttcgtaa ttaagtcgtt aaaccgtgtg ctctacgacc aaaagtataa
     7681 aacctttaag aactttcttt tttcttgtaa aaaaagaaac tagataaatc tctcatatct
     7741 tttattcaat aatcgcatca gattgcagta taaatttaac gatcactcat catgttcata
     7801 tttatcagag ctcgtgctat aattatacta attttataag gaggaaaaaa taaagagggt
     7861 tataatgaac gagaaaaata taaaacacag tcaaaacttt attacttcaa aacataatat
     7921 agataaaata atgacaaata taagattaaa tgaacatgat aatatctttg aaatcggctc
     7981 aggaaaaggg cattttaccc ttgaattagt acagaggtgt aatttcgtaa ctgccattga
     8041 aatagaccat aaattatgca aaactacaga aaataaactt gttgatcacg ataatttcca
     8101 agttttaaac aaggatatat tgcagtttaa atttcctaaa aaccaatcct ataaaatatt
     8161 tggtaatata ccttataaca taagtacgga tataatacgc aaaattgttt ttgatagtat
     8221 agctgatgag atttatttaa tcgtggaata cgagtttgct aaaagattat taaatacaaa
     8281 acgctcattg gcattatttt taatggcaga agttgatatt tctatattaa gtatggttcc
     8341 aagagaatat tttcatccta aacctaaagt gaatagctca cttatcagat taaatagaaa
     8401 aaaatcaaga atatcacaca aagataaaca gaagtataat tatttcgtta tgaaatgggt
     8461 taacaaagaa tacaagaaaa tatttacaaa aaatcaattt aacaattcct taaaacatgc
     8521 aggaattgac gatttaaaca atattagctt tgaacaattc ttatctcttt tcaatagcta
     8581 taaattattt aataagtaag ttaagggatg cataaactgc atcccttaac ttgtttttcg
     8641 tgtacctatt ttttgtgaat cgattatgtc ttttgcgcat tcacttcttt tctatataaa
     8701 tatgagcgaa gcgaataagc gtcggaaaag cagcaaaaag tttccttttt gctgttggag
     8761 catgggggtt cagggggtgc agtatctgac gtcaatgccg agcgaaagcg agccgaaggg
     8821 tagcatttac gttagataag gttctgttgc aaagttgaat ttatagtata attttaacaa
     8881 aaaggagtct tctgtatgaa ctatttcaga tataaacaat ttaacaagga tgttatcact
     8941 gtagccgttg gctactatct aagatatgca ttgagttatc gtgatatatc tgaaatatta
     9001 aggggacgtg gtgtaaacgt tcatcattca acggtctacc gttgggttca agaatatgcc
     9061 ccaattttat atcaaatttg gaagaaaaag cataaaaaag cttattacaa atggcgtatt
     9121 gatgagacgt acatcaaaat aaaaggaaaa tggagctatt tatatcgtgc cattgatgca
     9181 gagggacata cattagatat ttggttgcgt aagcaacgag ataatcattc agcatatgcg
     9241 tttattaaac gtctcattaa acaatttggt aaacctcaaa aggtaattac agatcaggca
     9301 ccttcaacga aggtagcaat ggctaaagta attaaagctt ttaaacttaa acctgactgc
     9361 cattgtacat cgaaatatct gaataacctc attgagcaag atcaccgtca tattaaagta
     9421 agaaagacaa ggtatcaaag tatcaataca gcaaagaata ctttaaaagg tattgaatgt
     9481 atttacgctc tatataaaaa gaaccgcagg tctcttcaga tctacggatt ttcgccatgc
     9541 cacgaaatta gcatcatgct agcaagttaa gcgaacactg acatgataaa ttagtggtta
     9601 gctatatttt ttactttgca acagaaccat ctttactgtt tgtgagttat ttaagtgagg
     9661 tgttgcctaa tacacaaatt atttattact tttaatttgt tctaatcctt tttttaagat
     9721 ttctctacca gcttgtgaaa cgttatcgaa atctttttct tgtgcgtatt tgataatctc
     9781 atctttcata tcgggatcaa ctaacaaatg tagtgatact tttttctttt taccaaaaaa
     9841 gactgaattt tcttcattat tattcatagt aatataacct cctttttgtg ctttcgtgta
     9901 attctattta attacacaat accacattta cacatgacat gtcatgacaa aaaagttaaa
     9961 aaagttttat aaattacatg acatgacatg taatactatg ttataattga tttatcaaat
    10021 agaaaaggtg ggttgtaatt ggataacata acatttcgta aacgtattga agaatatcga
    10081 aagcgatcta ttgagcaaaa gaaatatgag agcaaactaa attatcaatc aagatttggt
    10141 gtgaaagatg atgaagttag tacttttaat atcaaaggca ttgctacaga taaaaaagaa
    10201 aataagttag tcatggccga agatagagag gataaacaaa aagttctttt atacgccaat
    10261 aaagataatg atatgtatta tttgaattct ggtagcactt ataaagaggc tgttcaaaac
    10321 acttttggta atgaaaccaa ttacgaaatg gtagatgatg aattatttat ttataattca
    10381 aaaaatcaag cacttacaaa ctatgaccaa cttgatgagt atcacaatcg acaaaagcaa
    10441 ttacaatata acaccaaatt agaacaggaa cgaaagcaaa gattgactga tacaaataaa
    10501 gttagtgaaa atgctaaaga agatttagcg ttaagtttag gacttacagc aacagcattg
    10561 aaaggtaaca taaacatttc taatgttgaa aaagtcactg ataatgaaag tatggttact
    10621 atagaaaatg aaattaatgg taagtcagaa catttaattt cagactttaa agatagtttc
    10681 attgaaaagg ctaaagaaaa gctaactgtt tccccttcaa tgaggttagg atttgaagaa
    10741 tttaaaaacg cctcgggaca aatagcaatg ggatttacag agttttttgg cgctaggtat
    10801 gacgaaagca ctttagaaaa cgaccctaaa gttgtggcaa cagaaaaagg gtactctgtt
    10861 tctgtttttg ataaagacgg aaacaaaaaa gatttaacat cagctgacac ttttgaggag
    10921 gcagtaaaat tatccaaaga aatgaaacat gataactcgc tttctcgtag tgaaatagaa
    10981 ttaaatcaag aattagaaaa gaaaaaaata taaggaaggt tgattaatta tgattaaaaa
    11041 attcagttta acaactgttt atgtagcatt tttaagcatt gttttatcaa atataacact
    11101 tggcgcagaa aatccagggc cgaaaattga acaaggttta caacaagtac aaacattctt
    11161 aacaggccta attgttgctg ttggtatctg tgctggtgtt tggatagttc ttaaaaaatt
    11221 acctggaatt gatgatccaa tggtaaaaaa tgaaatgttt agaggcgttg gaatggtatt
    11281 agctggtgtg gctgttgggg cagcacttgt ttggttggtt ccatgggtat acaacctttt
    11341 ccaataaaca caacaaaagc tacattctag taatgtagct ttttgtttta aaaaggagtg
    11401 aattatatgt ctgttgagca agaagttaaa gatataatgc tcgatatgtt gggcgaagaa
    11461 aagaaagtta aagagaatat aatacctcgt aatgtagacg ctagttataa aatattctta
    11521 aatttaaacg gtaaagaatt agcaattgta tttgttcctt ttttactatt tctaacaata
    11581 gcatttggtg taacgttttt aatgggctta cttaatttaa taactggctt tatggttttt
    11641 atagtaggtt tgatttttgg tttaacaata tatggcttac taacaattag accaattagt
    11701 acaaaagaaa atataagaat gattgatacc ataaaacaat cacaacgatt tagcagaagg
    11761 cagaaagttt acttctataa aagtaaagaa ggattgggtg atgatgatgt ttaaaaaaaa
    11821 gaataagcaa aataaaaata acgaacaaca atttgaaatt ataaatagat atataaaagg
    11881 ggacggacgt aatcaaagta ttcaagaaga ttcactaata gctggttttt ataaagatta
    11941 cgttgttact aaagacggtt atatcagtgg aggtttaaat attactggtg taaatacaga
    12001 gttattaacg aagtttgagc aaaatgattt attagaagaa tattcatctt ttatttcaaa
    12061 cattctttac gacgaaccaa tgataaaaac aattacagaa ccagtaaata tacaaaatta
    12121 tataaaacac ctttacagac aagtattact tgatatgaag aataataata ataaaccaac
    12181 aagacgtggc caattaatag ctggtcgtat attgtttctt caagaaaagc tagcaaaagg
    12241 cgaaatgagt acaaagaaac attatatttt cttttcggaa aagataacag aaaatactgt
    12301 agcacaatta gatcatgcag tgaatagact acatgaaaag ataaacctta ataaagaggc
    12361 attacaacaa gcattttcac attatggttt agaaactaga cctatatatc aaacagaata
    12421 cttaaaccag ttttatgctt tatatgatta taaaggttat aacgactatc atcttagtaa
    12481 ttagaacgaa gggagtttat gattatggca tttttaaaaa agaaaaagca agagcaagtt
    12541 acaaataaaa ttcacaatga atcttttcaa aaattaacag aagtattaga tacagattct
    12601 gttgatagta tttatccttt tagttggata gagaaaaaat cgcatataga aacaggcgaa
    12661 aattatatta aaaatttatt agtagttgac taccctcaat cagtaaaagg ggcgtactta
    12721 tcaaatttat taaagaaaaa cggtaatatt caaataacta aatttattag accagcaaat
    12781 atagaaagaa tgattgacca tttaaacaac tcaatcaaaa acaaaacagc agaacaaatg
    12841 cgtactacag accctaaacg aaatgcaaca attaaaagag aaattgaaag tagtaaaaaa
    12901 caacttgata aatttttaga tgaaaaaaca ggatttatgt acatgtatat gtatatcacg
    12961 ttaaatggcg attcatacga aaagatacaa gcgctagaaa aagatgttaa gcgtacttta
    13021 acgagattaa gacttaaaac acatacacct acaaacgcaa tgcgagaatc atttcataca
    13081 gttcttcctt taaatagaaa cttcttatca gcatttacac aacaaaatat ggatacagca
    13141 acagcagggc atttctttat gtttgatgat tcagaaatta ttgatttaac acctaataca
    13201 tcagtttttg gaattaacaa aaatacagat tcattagtag cagttgattt taataacaaa
    13261 gaaaaaactt taaataaaaa tatgactatt atcggtacaa gtggtgtagg taaatctacc
    13321 ctcaatatga gaatgatttt agacaatatc aaaaaatcta taagacaatt tatcattgat
    13381 cccgaagatg aattttcata tataactaaa tattacggtg gaacagttgt aaatatttca
    13441 acaagttcaa atatcaaaat taatccattt gaaatttttt cagaagaagt atttgaaaaa
    13501 gaagatgaaa cagacaatga aacaacatca gatgttttaa cggaaaacaa cgaacacgaa
    13561 agccaaattg acacattagt tcgttctaaa atagggaagt taaaaacctt ctttagagtt
    13621 cttaaagatg aaatatctca aacagaaata tctgtattat cttcaacttt aagacagtta
    13681 tatcaagata aaggatttaa aggtaatgcg aaattatcag atttcaaaag cgaagattat
    13741 ccaactttaa cagaattata taacaaacta aaagacttag acccagaaaa atatgaggta
    13801 ttaaaggact taacacttat catagaagat tacacaatgg aacatggtac tactacaatc
    13861 tttgacggtt atacaaacat caaattagat aatgaaattg ttacttttaa ccttaaacca
    13921 ttacaaacag aaaaagatgt tcaaagtgca gcgtatttga atatattcag tttcttatgg
    13981 gacgaaataa caaaagatag aacaacagaa acagtattaa tgactgacga attacatttc
    14041 ttagcaacaa atgaatatag cttagatttt tattatcaag catacaagcg tattagaaaa
    14101 tatggcggtg gcgctattgc ctctactcaa caaattaaag atattcttag aacatcacaa
    14161 gaaataggtt cagctattat tgaaaatagt catactaaat tcttctttgg aatggataac
    14221 gtaggcgttg atgatgttgt tgataaatta ggattgaaat ttagcgatca agaaatatct
    14281 catttaacta aaaagaaaaa aggcgaggca ttattactat acggaacaca aagagcattt
    14341 ataagaattg atttagatag agaagaaaca agactttgga ataaagaatt atatgaaaca
    14401 atttatgaag aaccagcaga cgtagagccg aattatgttg aacaactagg attaacagat
    14461 attgatttag cagagttgga agaagaatta agacaagcag aaatgattta tgaataggag
    14521 gtaatctcat gaaaattaga aattttaatg aaggaacatt ggtaggaaaa cataaccact
    14581 tagaatatat catcaatgtt gatttgtgcc atatatcaga tatagacgaa attagatatg
    14641 acttaacaga acctaatgaa ttgttttttg aagttaaaga tttacaaaag gaaggcgatt
    14701 attttcatat catttacaac actgataatg aatataattc cttcctatca gcaaaaaaag
    14761 aaagcaaagc actcaaatta tctttaatgg attatgtgtt aaaagttgat ccattaaagg
    14821 acaatataac tgttatgcac ccagcgaacc tattttttaa aaatattgag gatataaaaa
    14881 taggattcaa aggccatgaa tatttaccta aacctaaaat aaataattta gaacagtata
    14941 aattgttaat aatgagtaca ttatcacaat acacgtttga taagtattat cgcaataaat
    15001 ttgaagtttt atcaaaagaa aaagatgatt ttttccataa agtaaataat gcagaaactt
    15061 ttgaaaaatt gaaagagatt gtaagacatg aattgaatca agtacagaca gattatttac
    15121 tgaatgaaga aaaacgtaaa agagaaacac gaaaaaagta cattagaaat ttaatacttg
    15181 gttttgttgg tattgcaata gttataagtt taatttcatt tatgattata aacggaaagc
    15241 aacaagaatt agatagcaaa atagcacaag cagacaaaca agaacaaaga agtaaagtat
    15301 atgaaaatct ttacaatggc aatgttgatc aagcagttaa aggcatgaaa cgtgacgata
    15361 gctttaacaa aaaagatatt gaaaaaacat taaaaaaaga aaagaaatat gaagaactaa
    15421 ttgaattgag tagtaaaaac acaccttatg taattgaaca attatataaa gaaggtaagc
    15481 agaataaaat aagagagtta gctttcaatt ttgaaaataa cgatacattg agtttagaaa
    15541 agaaaatatt agacaaagac ggaacagcat ttagtgtagg ctcaacaggt aaatacgaag
    15601 aacaaagtaa acgtttggct ttagcgtcag ctaaagaagg ttatgttgaa tcagctaaag
    15661 atattaataa aaaacttaaa gataatgaag ttgaagaaga aataaataaa gctgaaatta
    15721 aacaactaaa agaagaaaaa gacagcacga aggataaaga caagaaaaaa gaaatccaaa
    15781 aagatataga ggaattagag aagaaatagg agggaggtaa agtatcatgt ggagtgctat
    15841 tgctaaagga ataacaatgc tgatgaagaa aaaagcatta tccaaaatat taaaaccagt
    15901 aatagctata gtaataggct ttttccttct tatttttata atgattgctt atctagtagg
    15961 atctttcact aaagaaatta atgagagtgg cgaacaaaaa atgaaagagg ctgaatcaac
    16021 agcaacaggt gcgtgtactg gtggaagtgt tgacggttcg ggtatctctg cttttgaaaa
    16081 aaacgccaaa ggtggcgcat tagaaggtaa aggtaaggat atggttaaaa ttgctaaaaa
    16141 aaataaaata ccaccaaaat tatttatagc aattgtagct tctgagtcag aatggggaag
    16201 aggggcaaat gcaacaaaac aaaaaaaccc cctatctata atgggggctg gccctctaca
    16261 agtttaccct tcaattgaag aaggacttga taaaggtgca aaaaatttat atgacttata
    16321 catttctgaa ggtttgacaa ctcccgagaa aatcgggcca aaatacgcac cagtaggcgc
    16381 tagtaatgac ccagatgact taaatagtaa ctgggtacct acagttaaga aaatcatgaa
    16441 gtcattcggt ggcaaagagg ctaaatgttc tactgaaagc agtggtggag gttcagacgg
    16501 aaaaggattt gattttaaag gagaattccc taaacctgac aaatcgaaat ataacggtca
    16561 atcttatcca tggggacagt gtacttggta tgtacatcaa cgtagaaaag aaattggcaa
    16621 accagtacct ttaacttggg gtaatggtgg ggactggggc gataatgcaa aagcgcaagg
    16681 ctgggaagta ggtagtaagc cgaaagctgg cgctggcgcc tctgtaaaac ccggtaactt
    16741 tggcgcacca ccaccgtatg gacacatcat gtttgtcgaa aaagttaaaa aagacggtgg
    16801 aattgtagtt agtgaggcca atgtaaaagg cctaggagtt ataagttcaa gagaattttc
    16861 aaaagcagaa acacaacgta tgcaatttat ttatgataag taggtgtaaa aaatgaaaaa
    16921 attattaact atagttattt tattcacttt ggttctggct ggttgtggcc aaaatcaaag
    16981 tgagaaaaat agtgaaaaac ataatgaaga aaaaacagta gatactacag aagaaagaaa
    17041 cgatatgata aaaggtctaa ttgaatatgg ttatgaaaat gatgattata aaggttataa
    17101 gcatatgaaa gatatattat ctgaaaagtt gcaaaagcaa gcagaattgc aaaatcaatc
    17161 agcacaaact aaaggtgtaa aaaaagaaac taaagacatt aaactttatc aagacgtaga
    17221 taatgatgat gaattgattt attctattaa actttcaatt acaaacaaaa aagagaaaaa
    17281 ctctgactac tcaatgagat atgggaaaat tgaattaacg gaagaagaag gtaaacaaaa
    17341 gatagataat gtcgaagaac taacacaaag aaatttagta agtatgaatc aagaatagaa
    17401 agaggtaata cttatgaaca ctttaattct atgtgaaaaa ccttcacaag caatggactt
    17461 aagcactgtt tttgcaaaaa agaaaaagca aaatggatat atggaaattt cagatgaaca
    17521 attaaatgta agtggctttt taacttgggc agttggtcat ttagtcgaat tgaaggaacc
    17581 acaagaatat gacgaaaaat ataaaaattt tagcacatat cctatattgt tagaaaaaga
    17641 cgattttcaa tttaaagtat ctgacaaaac gaaagatcaa tttaacaaca ttaaaaaaat
    17701 atttaaagaa aacaagattg atgaagttat tattgctact gacccagcta gagaaggcga
    17761 aaatatagca tataaaattt taaatcaatt gaaagtaaca gataaagtta ctataaaaag
    17821 attgtggctt acttctaaag tagaaagcag tataagaaag gcttttaaaa atatattacc
    17881 taaagaaaaa acttatggat tttacaaaga gggcagggct agagaattaa gtgattggtt
    17941 agtaggaatt aacttatcac gtcatttcac taaaatttca cgagaattag gaaatgacgg
    18001 tgttattcat atcggtagag tatctagtcc tacattaaac atggtttaca acagagagaa
    18061 taacattaaa ggttttaaag gtaaaaagtt ttataaagtt tcagcgacta ttaacaaaga
    18121 tgaacaagaa gtgaaaacag agttaaaaaa caaatttgac agtgaagatg aattgcacga
    18181 atttttgttt gaaaatgata ttacagattt aacacaaaaa gggttagtta ctgatattga
    18241 aaaagaaata ggctatacaa tgccacctaa attttatgac ttatcagctt tacaagaaga
    18301 tatgaatgat aaatataaaa taagtgcgaa acgaacatta gaaatcgcac agacattata
    18361 tgagaagaaa ttaatcacat atccaagaac tgattcaaga tatatcacag aagatgaaaa
    18421 agaaatgtta ttagaaaata tagactattt aaaagaaata acaaagatta atttgaataa
    18481 tgaattaact aataacagct tgattaatcc ttctaaaata gaagatcatt acgcaatatt
    18541 aataactgga aatgatttta acaaagtaga tttaaaagaa gaagaaatca atgtttataa
    18601 aagtatatta caaaatgtgg ccatgaattt tatggataaa gaacaatatg aaacgactac
    18661 tatagaaatc gctgttaaaa agcttatgtt tgaagtgaaa ggtaaaatta ttcaagataa
    18721 cggatttaaa gctttgttaa ataaacaaaa aacttccgaa gaaacaattc ctaattttga
    18781 aaaaaatgaa gaagtagaca ttgaattaga tttgttagaa aaagaaacga cacctccaaa
    18841 aagatataca gaaaaaacat tgttaaaagc aatggccaat cctatagaaa cactagaaga
    18901 tgaaggctta aagtctacac ttaaagaagt taaaggttta ggcacaccag caactagagc
    18961 cgatattata gaaaacttga agaaaaataa atatattcaa gtacaaaaaa acaaaattta
    19021 tattactaaa aatggtatat tagcttgttt attattggaa ggacatttac tttcaaaacc
    19081 agacttaaca ggacaatggg aaaaatattt gaatggtatt agtaaaggcg aaaaagatga
    19141 tgattcattt ataaatacca ttaatgaaat gattaaaaaa acaattaatg aagaagttaa
    19201 aaataaagaa agtatacaaa aagtggccaa agagaaagta tcgactaaca atatagcaaa
    19261 atgccctgct tgcgataatg gctatttaat agatagaaaa ggtttttatg gttgtacaga
    19321 gtacaataac ggttgtgaat ttactattcc taaaaaattg ttagaaaaaa gtatacctcc
    19381 aactgtagta aaagcattat gtgaaagtaa gacaacaaaa aaattgaaag gctttaaatc
    19441 aaaaaaaagt ggaaagtcat ttgattgtaa gttgatatta acaaaagaaa acaaacttca
    19501 attttcattc gattaaaagg aggataagaa agtgaaaaaa ggaatattca ttttaactgg
    19561 tattatttgg ctagtattaa tatatttagc gcaaatatta gcatatgctt taaatacact
    19621 aagtaatact agcaataagc aaaagatatt tagtgatata tcacagttgt ttatacctcc
    19681 agctaaacac ccaataagca ctattatcgg ttttgtatct gataaaaata cagtgttttt
    19741 tgtaataggt gtaatagcaa caattatttg tatatatatt cttataaaac aattatttga
    19801 gagcaaagac ggaaacgaaa aaaatcaaga ctataaaatt gctaaacatg gttctcatgg
    19861 atcagctaaa tttgccgaag atagcgaatt gttttcagaa ggacattata aaaaaatgaa
    19921 agaaaacgac attacgaact atgtttataa cagtttagat aaatcattaa tagaagaaag
    19981 aagtgataag gaatgactac acttttaggc gaattagaaa gtaaagcaac ttctataaat
    20041 aaaaagaatc tagtaataca agattttgat actaaatgcc ctaatagaaa tatatttgtg
    20101 gtaggagggc caggttccta taagtcagct gggtatgtta ttcctaatgt tattgttaaa
    20161 aatcaacaat caatagttgt aactgaccct agtggcgaag tttatgaaaa aacatctaat
    20221 attaaacgca tgcaaggttt tgatgttaga gtagtaaatt tcaaaaactt tttagcctct
    20281 gatagacaaa acttttttga ttatattgat aaagattctg attgttcaat agttgctgaa
    20341 ttaattatta aatcagctgg ggattctaaa ataaataaag acgtatggta taaagcctct
    20401 gtaggattat taaattcatt gcttttatac gctaaatatg aatttgaacc agaaaaacga
    20461 actataggaa acattattaa atttattcaa aataacaaac ctaatcaaga tgaagaagga
    20521 tcagttgaat tagataaacg ctttaatgaa ttatctaaag accacccagc tagagaaagt
    20581 tatgaatttg gttttgcagt atcagaagga agaacaagag caagtattat actaaccttt
    20641 gtagccgatt tacgaaatta cattgataac gaaattagaa gttatacaag cgattctgat
    20701 tttgatttac gagatgtagg attaagaaaa actattatat atgtaatgtt gccagttttg
    20761 gggaacactg ttcaatcact ttctagttta ttcttctctc aaatgttcca acagctatat
    20821 aggttagggg acgaaaacgg tgctagactt ccagtcccag tagatttttt actagacgaa
    20881 tggccaaata tcggcgcaat accagactat gaagaaactt tagcaacttg tcgtaagtat
    20941 ggtattagta tcacaacaat tgttcaatct atatcacaag cagtagataa atataataaa
    21001 gataaagcta acgctattat aggtaaccac gcagttattt tatgtttagg taatgtgaat
    21061 aatgatacag caaaatatat aaaagaagaa ttaggtaatg ctactgtaga gtttgaaaca
    21121 agtagtgaag gttcttctag tggtaaagat agcagaagta aatcatcaaa taaaaatgta
    21181 agctacactg gaagggcatt actaaatgaa gatgaaataa gtaatatgca acaggataaa
    21241 gctattctta taactaaaaa tagaaatcct aaaattatta aaaagttagc atattttaaa
    21301 atgttcccta atttaacaga aacgtatata gcacctcaaa acgaatacaa acgtaaaaaa
    21361 aaccagtcta tgattgataa gcataataga ttaagagaag aatgggataa aaaacaagag
    21421 aaaaataaac agcaaaaact agaagaatat aaagaagaac aaagacagaa agagttagag
    21481 aaagaacaac aaccacaaga agaacaacaa aatgagaaag taaaagaaag taaagacaaa
    21541 aacgatcaag aagataagaa agacgagcaa caaaaaatta atgattctaa gaaagcattc
    21601 tacgaaaaat taaaacaaaa acaagctaaa taaaagtaag attttgcatt acatgacatg
    21661 acatgtaatg caaaatctgt tatacttgta ttgaaagtag aggtggttga atggattgga
    21721 ttaaagacgc tattaaagaa ctgaccgaag gtattgcaga cggtatgatg aattttatat
    21781 ttcagtttct ttatacgtta ttttacgaac ctttaaaatt ctttatatgg ttgttagata
    21841 aaatacttat tgatcctaat agtatttcaa gtgattacat ttcaaacgcc tctgtattag
    21901 ttaatagctt aatcacttca atagcaatat gtgtgtttgc ttttaaaatg gttcaagtta
    21961 tgaaacaaaa tgcagaaggt aatgctgaaa gtccaggcta ttatgtagca caattattac
    22021 caagttcttt attggtagca gttttaccat ggctagttga tataatgact aaattatctt
    22081 attcagcgac tagggcattt ttagatgtag gtcaaaaaag ttatttagaa actattaaag
    22141 aatggagttc tttaaaaaaa ggtcaagacg gatttaaaga aatgctaggt tctatgggga
    22201 ctatggcagg tagtcaaatt atgtttattc tatttattct attgatttta gtatttactg
    22261 tagtatttat tttccaattt gttagtagga tagctgattt agtaataatg aaagttgttg
    22321 ccccgttagt agcagtttct ttattagcag atgaaaataa ttatataggt gtatggtggc
    22381 gtgaattatt agcaattagt attcaattac cattacaagt gtttactttc tttggaggaa
    22441 taaatttatt ctttggtgca aagctagacg taggcacatt attattaggt ataggattct
    22501 ttattattac agttaaatcg ccttccttta ttagatcaat ggtttactct actggaagtg
    22561 ggcgcatggc aactggaatg gctggaagtg gtgcaaaact tctagttaga aaaatgttat
    22621 ctaaataaag aaaggaagat atttatgata aacaaagtaa tatatagtgg acgtatcgca
    22681 actgatttaa aattaagaaa aagtaaaaat gaaaagtctt atgttttctt taacatagct
    22741 gtacctaggc agtttgataa tgatagaaca gattttatta attgtgttgt atggggaaaa
    22801 caagcagaaa gtttagttga ttatcaaagt aaaggtaatc taattattat tgaaggttca
    22861 actgaaacat ataaaaaaga caatattaat atgtctagat gtttggttga aaagactatc
    22921 tttttagaaa gcaaaaaaga aaacaaaaaa catgacgtgt cagaagatga cgctataagc
    22981 ccagcagaag atagtggcaa cgataaatct atctctgatg atgacttacc attttaaaac
    23041 tataaaagga cgtgtgaaaa cacgttcttt tttaaaaaat aggagtgatt tagatgaaag
    23101 taacaaatac aattagattt gaagaagaaa agaaaaactt aattgataat gtagtaaata
    23161 cactagaaga atataaagat gttatcgaca gtgaattgcg tactattaga aacactaatc
    23221 atttagttat gagaaataat ttggttctgt tgcaaagttg aatttataat ataattttaa
    23281 caaaaaggag tcttctgtat gaactatttc agatataaac aatttaacaa ggatgttatc
    23341 actgtagccg ttggctacta tctaagatat gcattgagct atcgtgatat atctgaaata
    23401 ttaagagaac gtggtgtaaa cgttcatcat tcaacgatct accgttgggt tcaagaatat
    23461 gccccaattt tgtatcaaat ttggaagaaa aagcataaaa aagcttatta caaatggcgt
    23521 attgatgaga cgtacatcaa aataaaagga aaatggagct atttatatcg tgccattgat
    23581 gcagagggac atacattaga tatttggttg cgtaagcaac gagataatca ttcagcatat
    23641 gcgtttatca aacgtctcat taaacaattt ggtaaacctc aaaaggtaat tacagatcag
    23701 gcaccttcaa cgaaagtagc aatagctaaa gtaattaaag cttttaaact taaacctgac
    23761 tgtcattgta catcgaaata tctgaataac ctcattgagc aagatcaccg tcatattaaa
    23821 gtaagaaaga caagatatca aagtatcaat acggcaaaaa atacactcaa aggcattgaa
    23881 tgtatttacg ctctatataa aaagaaccgc agatctcttc agatctacgg attttcgcca
    23941 tgccacgaaa ttagcatcat gctagcaagt taagcgaaca ctgacatgat aaattagtgg
    24001 ttagctatat tttttacttt gcaacagaac caaataaaag ataaaataac atcttggctt
    24061 gataaagata acaacaaaaa cgaataatat aggaggggtt ttttggggaa tttagatttt
    24121 gatcacgaag gatacagaaa actattacca ttaaaagatt tcaaacattt tataaaacat
    24181 agcgacagca agactagaaa tcattttatt ggtatggctt ttaataataa aacagatgtg
    24241 tttagtcgta acttctctaa taaaatgata aacatattcc ctaaaaatga attttatatt
    24301 catatacaac aatttccaga gaatgatagc ccttcttata tggtatacaa cactgatatt
    24361 acagcattta ttcagtttag gttagttggg cgatcagaaa ataagtattt agaaaacatt
    24421 atcagagatt atggcgtatt aatagaagtt gaggccttac attcatttaa aaaaggtatg
    24481 ggggcaatgc ttgtaagtca attggaaaag ttatcagata aactgtttat acctatatat
    24541 ctttatgata ctaatttaaa agatgaatta tattatcaag acttaggatt ctttgatact
    24601 actaaaaaag ggaatcatgg agaaccactt ttagtatata aacctaaaaa tctagaaact
    24661 aataaaaaag aaaagcctat taaatcttta ttcaagaaag tattcaatat caattagcct
    24721 acagtattaa agaggtgggg taactcattt ctttaatact tattttatta acaggggttt
    24781 aatatatgga ttacacaaat caaaaaagaa aatacataat atttggtatt gttcttgcta
    24841 taacacttct aattgttgga attgcttact atttaatcag tttgaataat gctaaaggac
    24901 aagttaaaga atttgaaaaa ttagtacagc ataatgacta caatagtatt gctaaaaagt
    24961 tatctaataa agaagaaact ttatctgaaa atgatgctaa aaactttgtg ttatttgtta
    25021 aaagtaaaga aaatcaagaa caatacaatg agcaaataca aaaaattaaa agtaatattg
    25081 ataaaaataa agacaataat accgtgtatg gctctataac agatcaatac ggaaataacc
    25141 taataactat taagaaaaac ggaaagactt tcttttttat agataaatta gaattcaaac
    25201 ctaaacttac cagcgtttat gtgaaagaat ttaataacac tggaatttac aaatatcagc
    25261 aagaaaatgc taaaaaggta atagcagaaa gcaatcaaac aacagaatta ggcaagttct
    25321 ttattggtaa atatagtatt aaaacagata aaacaattga agattcaatt cacaatggga
    25381 ctttgacagg aaaaatagat atagatttaa gcaatagagg aaacaataat aagatatatg
    25441 cagatgaaga ttttaaccaa agctggttta aggttaagct aaacaatgat agtttattag
    25501 aaaaaaatag ttacaaactt ttaattgatg ataaagatgt tgattataat tccaaaaaga
    25561 catatggaaa gtattacaat ccaactgaat taagtgtata tgcgattgga aaattagagg
    25621 gtaaagagtt taaaactaac agaataaata taagacgtaa ttatgataat aaacctcaaa
    25681 atttaaaatt aagttttaag gaatctcaaa taagagatta tgagagtaaa agtaaaaagg
    25741 ttaaagaaaa agctaaaagc tatattaaag aatatacgaa agagttaaac aaagcatata
    25801 aaaagaaaga ttataaatat atatctgact acgttaaaaa taactctcaa ttagaaaaac
    25861 aactaaaaaa acaggttaag tctaaatcaa aagttaaatt taaagatgtt aagataaaca
    25921 acgttaaacg tgataaaaac aaaatatata ttgagttaag taaaaccaac aatggtaatg
    25981 tgtttcaaac gaaatatacc ttagattacg ataatgtatc aaatgaattt ctagtagaag
    26041 attcacatga taattaaaat aattcaaaca ccaatgacat taaattcatt ggtgtttttt
    26101 actgtacgct aacaatacta cttaaaggta tttttagttt attgtttgaa ttggaattag
    26161 tgataatcat aaatccatta aattcatcta ttttgttaat gtaacattga atcgaatata
    26221 tatatccgtc tttccagtaa tctaaatcag ttaatatatt tttactaatc ttactactta
    26281 ctttctcatt aatttcttgt agctggtcat cagacaatag aggcatattt attttatttt
    26341 gatcttctat gtgttgttcc aatatttcat attgctgggg tatcgtctta aatgcgttcc
    26401 atttaactat tcctctacct tttggaatat gtggatttaa gtattcccta ggtatgtttc
    26461 tataatcagt ttcatatttg tacggttcgg gcatattagg atttattatt ttcatatcag
    26521 taaacacctc aaccaaatta tagaacatat gttcgtaaaa ataaagagtg aaataagagt
    26581 attataaacg attgtattta ttacactgat aattactttt cttaatagcg ttataatggg
    26641 ttgactggtg tattaaaatc ttgtattata atcatagtaa gataattaac aaataacatg
    26701 gcaaataata caaatagatt agctctcatt tgcattgaga attaatttta tagataacta
    26761 tacattaaaa acaatataca acgctatttt agaaaggata attacaatta tggccaatat
    26821 tggttatgct cgtgtatcta ccagagatca aagtttagat ttacaaatag acgctttgag
    26881 taattttggt tgtgagaaaa tatttagcga aaaagttagt gggcgtaaag taaatagaac
    26941 tgaactagat aaatgtttag attatttacg tgaaggcgac actttagtta tttacaagct
    27001 agatagatta ggcaggacta ctaagcaact gatagattta gcccaatggt tagaaaataa
    27061 taatattgaa ttacaaatta ttgatatgaa tatcaataca aaagacccaa tgggaaagat
    27121 gttttttaca atgatgagtg cttttgctga attagaggct aacttattaa gcgaaagaac
    27181 taaaaaaggt ttagaatcag ctagagcaag aggtaacatg ggaggcagaa aagcaatgcc
    27241 acaagaaaaa aaagaataca ttaaacattt atacgatacc aaagaatata caggacaaga
    27301 aattgctaaa aaaacgaatg taagtagaga tactgtatat cgcattttac gagagtttaa
    27361 aaagtaatcc taaacattgc ataacatgac aggtattgat ataatataag taagaaaaga
    27421 atcggcgttg tggcgcagat ataaaaatta atactacacg aactagaatc ggcgttgtgg
    27481 cgcagatata aaaattaata ctgcacgaac tagaatcggc gttgtggcgc agatataaaa
    27541 attaatactg cacggaaaga aacaactata gagatcaaaa cacattatat tgttttaagg
    27601 aggcgtatat tacgcctctt ttttattaaa tttatggagt gaataacaat ggaagttgtt
    27661 cgtttaaatc aaaacctatt taataaacta cgaggaaacg aaatatcaag caataaaaat
    27721 ggttcaagac catattatta ttctttcaaa cgtaataata atagagtttg tatacctttt
    27781 agaacaaatg cacaaaaggt acctaataaa tataaaatta atttaggagg cgaacagccc
    27841 gataaaccta attcagctat tgatttaaca aagtctatag taattagtaa tgatgaatat
    27901 cttaataaca ggtcaaaagc taaaatacca caaaatgtta ataatttttt aaagcaacaa
    27961 gcaccagcta ttgaacaaaa atacgatact atgtctaatg attacataaa agcaaaagct
    28021 agtttaagta agataccttt agttaaatat tcaactatgc aatacttcca caaagaattg
    28081 aatattcaag atagtattga taatcaacaa actaaaaatg ctattaatga attaatatct
    28141 aatgggaaat caaataaata taataaatta caatcttctc tgcctaatga aaaattaaat
    28201 ttgctagatg attatgaaac tctatatgag tttaaaagcc taacagacta cccagctaaa
    28261 ataaattcta atgatattga taatcctttc ttagaagttg agaaaaataa caaacatttt
    28321 actttgtctg cactaactat taaaaatgaa ccagaaaagc atgtaaaaga ctttttaaat
    28381 tatgatatag agaatgaaaa gaataaagat attgatttag atttataagg cctgtaaaaa
    28441 aggccttttt tctttttatt tattatgaca cgacatgaaa tgacacgtca caaatggtat
    28501 aattactata tggaggttat atttacatta ggtttttatt aaaaaaagga gtgatttaat
    28561 aatgagattt acaccccgag gaattttgaa caacaccgat tatgaactaa attctgaatt
    28621 ttattatgtg ccagcaagtg ataaacaaat gaatgatcaa agagatatga ctaataaaag
    28681 catagtaggt aatttagtct atagaaataa tttctataac gaagtgtata ctcaaccagt
    28741 ttatgattta gacgattcta acgaaaaata tcaaacacca catattataa gtatagatga
    28801 ttctgaattt gattataact taactaattt agatgattat tttactaaag atacagcaaa
    28861 taaaggttat gaaaagctag taaatgccat taaatcagaa gaaattacct attttgacag
    28921 tgatattaat gaagttgatg attttacaca acaagatgaa tattcaaatg attggtatac
    28981 taacactttt gtggatttag tattaagtat gaaaggatat tcatatcatg tagaaccaaa
    29041 tagagaatct gttattgagg attcacatat cataacagaa aatgatatta cttataatgt
    29101 aagctataac cccgaaaaac atcatttata tattaatgac ttcccagcaa ttccaataga
    29161 agaaaacgat aatataagat tattaaatga taacttaact caagacatgg aaaaaactta
    29221 cgataatata aactataatt tttcatacaa tgattttaaa acacttgaag atgattctta
    29281 tatttatatt gatttaacag attataaaga taacgaaggt aaatttgtta aaaatctaat
    29341 agaagatata ccacctaatg aaattattaa agatagatta aaacaaaata ttaatttatt
    29401 tgacgaacga gcaaattata atgccttagc tgtttataga agggatttag aagatttttc
    29461 agatagaaat aatttagata gcttagataa agttaaagat ttaaaaacat tctatgatac
    29521 ggaaattaat attaaaggat tgaacattaa caacgatatt gagaaaaagg ctttaaataa
    29581 tcaattagcc tttaaccttt ataatgaacc gttaaataac atgtttagag ataacaatgt
    29641 tttatatgaa gtttatgaaa aagaaattta tgatgaaaaa attccccttt ctatagaaga
    29701 tagaaaagaa gtgaaaactt atttagatga cgctagaaac aatttttcaa ataatttcta
    29761 tgaatataca acgaacaaat catctatttt agctgaaaat agtttaactg ttttagataa
    29821 agctaaatat gatttagaat ttgcccctgt atctaatcat ttatacaaag aaagagaaaa
    29881 tttttacgaa ggaatgaaac aagctaccct gcccttacac aatattacta aagaacaata
    29941 taaagaaaga gaaaatgata ttgaaataat cggtcatttt aaaaactata tcaatactga
    30001 attacatgga acaaagagtt ctgaattcaa acctaatttc gtaaatgatt ctttagaaaa
    30061 tgaaactaac tcaatagctt ttgaagatat tataaatgga tcagaagaaa cacatagtaa
    30121 tattattaat tctattaaaa atgaattaaa gcaagaaaga gataatttag aaatgtagga
    30181 ggtacaatat gctaaaaaca tatactgaaa tcattggaag tgaattgcca atttatataa
    30241 caaaatcaga aacaagcgaa ttactatttt cagaagaatt agataaaaat ttaaaatatg
    30301 aagttgctgg atattatcta tataatgcta aaaaagactt atacaaagaa ctttataaac
    30361 ctattagcga ggtgtagtat atggcttatt caaaaggaaa ttataaaaag aaaaaaatag
    30421 attcaataat agaagaattg aataataagc tagatgactt caaaaacaat gacaaaacct
    30481 ataaggaatt tttagatact acagcgaaat ttcacaacta ttcaattaat aatattattc
    30541 taattgctgg ccaaaatcca gaggctacag ctgtagctgg ttataaagca tggaaaaata
    30601 aatttgatag acaagtgcaa aaaggtgcaa aaagtatgaa tataattgcc cctattgtac
    30661 aaaaacgaaa tgtagaaatt aaagatgata acggtaatat agtacgtgat aataacggta
    30721 atcctaaaac tgaacgaaaa cccgtaatta ctggatatag agcgcataat gtgtttgatg
    30781 tggcagatac gaaaggcaag cctttaataa cagcaaaaga cctaataaaa accgaatttg
    30841 aaaactctaa cgactataaa gacttatata atgaatttaa agattatatt aatgaagaat
    30901 taacacctag tgtagaggaa aaacattttc ttgatgatcc tactttatct aatggcgcta
    30961 aaggttatta tagtcctaaa tctgatgaaa ttgtaatctc tgatgatttg tcatatgata
    31021 tgcgctttaa aactttaata catgaatatg cacactctca attacacaat aatgatatag
    31081 gtaaaacgca aatatctgaa catagtagat cattaaaaga aatcgaggct gaaagttctg
    31141 cttatgtagt agctaattat tacggtttag acactagcga ttattcttta ggttatttaa
    31201 gtggctgggg gcataatata agtgatgatg aattaaaagc ccacataaaa aatatacatt
    31261 cgttcgcaaa aactacaatt gaagaaataa attcattgcc agagttttct caatatatag
    31321 ataaaaaatt agaatcagaa atgaacaaag atgtatataa agacctttca acaatgatag
    31381 ataccaatct aaaaaatggt tttgataaaa taactattat caaaggtaat ttagttaatg
    31441 attatggact taatgaaatt tctgagaata gttatgaaaa tgatgatttt aaagtgaata
    31501 ttgattacaa aggatttaat actaataatt cgcaagatca agctaaaatt gagttaatta
    31561 ataagcatga tgattcattg aatagagatt acaacttcac gcaaacttat aaccgaaatg
    31621 taattaataa caccacaact atttttgtac aagatgatga taatgaagat aaaaacaaaa
    31681 aatatatcca tgaacgagat atagacggta atatattaga agaaaaacat aaattaagcc
    31741 cacaagatga aatagtatca tttgaaaact ttgtaaataa atcagttgaa gaaaatggcc
    31801 taaaagatac attacgccaa tttgtaagta atggtgtatt aatgggctat gaattaaatg
    31861 ttgataatat tgataataca aatgaaactt acttttcaat gaataaaaat caacaaaatg
    31921 gccaacgatc aaatatgact gctaaattag aacatgatac taacgaaaat gtttatatag
    31981 attttaaaat taaaaattca gctggtatta aaaacatatc ctatactgaa agtaatgaag
    32041 aatttaataa agatgaacag aataaagaaa ttgaaaacaa acaagaagaa gaaattgata
    32101 tataaaaaga aggcatatac gccttctttt tttatacaat actatttata agtgcatacc
    32161 tcttttattt ttcaactcat ggcgctgttt actgtgattc ttacctttgt actgatgatt
    32221 tatatacttc ggcatacgtt ctctaaatat ctcattaaaa ttaaatatca ttgaatctag
    32281 tccagcattt attaaaccat aggcttgttg ttttctattg taattattgt aagtttcttt
    32341 atctactaga atatcattac cttcataaaa ctcttcaatg ttatctttgc ttatttcgtc
    32401 ccctacttca ttggattctt gatataaatg ttttaaatca ttgttatcac tataatcaaa
    32461 gtcatattca ctcaataatt tcttttgaat agccccaaat acaaatttat catgctgatt
    32521 tttattaggt ttaaattctt tttcttgtaa caacttaact tgttcagtta tatattttct
    32581 atcttcatca ctgtatttag gaataaaatt acctgtttct aacatttcaa ttgtgttttc
    32641 tgtaccatga taagttttaa aatcaattaa ttgttgtttt tctttaatgt cagttacttc
    32701 attaaaagct ttataatctt catcatctgt aaataattcc tttatttgta catcataata
    32761 atcttctagt atattttcag catttctaaa aacttctaat ttgttagtat aataatctat
    32821 tttcaaacta tcttccatac cttcatgttt attctctaac acatcatcaa aagacaagtt
    32881 atttttttcg agaatatttg aaagtttatc ggcaaagaaa ttcgattctt tttcaataga
    32941 ttctaaactt atatctctgt tacctaaaac tgtattaagg cttatttgag cctcttttat
    33001 gcgtttctct ttaactatat cctctagttc attattagct ggtaaaacat ctctatcatt
    33061 taatatagtg cgtgtgataa agattttttc atcatcacta tagtttaatg attgatcggg
    33121 ataattttta tcaaagaaaa ttccagcttg tttttcaaat acctcattta tagattcaag
    33181 ttttttctgt ctatcctcta tatcctcaat tttatttaat ctatcttcat catcagtgat
    33241 taatgaagtt tttttgtttt aaatcatata gtctttcatt ttccttatac atatttatag
    33301 gtgttacata aatttttaaa tctttggcca tattttttaa tgtagtagaa tctgatttat
    33361 tcatataact aaaagcattt aatttgtgag atttcatatc atctacttca ttaaacatct
    33421 tatcaatttt ttgctgattt ctctttttaa tactttcatt atgtttcgat attgaagatt
    33481 tttttcctgt ttcatcttca aattttcgtg ctttccaacc ttcttttttt gttggctcta
    33541 aatctatatt ttgattttta tatgaatcag cagaaactct aacagaaaaa ccattctttt
    33601 ctaggtgttt attttgaaca ttttcccacc gttttcgcca ttcattatgt ttttcttttg
    33661 tattccaatc tctaatataa tcattgccct ttcgcttagg ttcaaattca ttatttttat
    33721 ctaaaccacg taatgtacat aataaatgtg cgtgaggatt ttcttcattt attttatgaa
    33781 tatttagatc aacaatcatt ccttcattag ataaggattc agcaaattct tttgctaatt
    33841 caatattact atttggatca aattcattcg gcaaaccaat tataatttct cgtgcaactt
    33901 gactattttt tctgttctca acatcatgaa ctttattcca caaatattct ctatctttaa
    33961 acttatcatc agcattatta ggtaataaaa tttcactata atcacattgc ttatttgagt
    34021 aatctttaaa ttcgttttcc ttaaaatctt taatcctact agcgctatta taggcacttt
    34081 ttgcagttgc actttgtcca tttgcttttg atacaaactt attttgaaaa tggtacattg
    34141 ccataataaa atctccttaa aaaacaaata ttgagcgaag gcgaaataaa ttaaaaatta
    34201 atttttaatt tcacgaattt agcacgcgaa cgtaacgttc gcataagtgc gcccttacgg
    34261 gatttaacta gattataacg gtaaaacttg aatctgtcaa acgaaaaggt tataattaaa
    34321 ttaataaaaa atatggaggt tttatttatg gctgatattc aaaaaatgtt agaacaaaaa
    34381 gaaaaacttc aagaaaaaat taaagaagaa aagaaaaaag aatatgaaaa atttggaaga
    34441 tggttcttca ataaatttaa agtaaataga tcagcagacg caaagaaaat tataaataaa
    34501 aatttgctta atattgaaga tactaaagaa cacaatttag aaagaaatga aattatagaa
    34561 gaaactaaaa attccaatga agaaaacaaa gaaataaatg aaataaacca caatatttaa
    34621 tagatattaa ctaatattaa tatgatgaaa gacttataaa ataattggtt tactaatagc
    34681 aaaatctaca gtagtcaata ctttaaaaat aggaggtttt attatgattt tattatcaac
    34741 agctggcgaa aatgctgttc atattaaccc tatttttaga ttttttctat attttattat
    34801 gtgtgttcct atgacagttg ctttatgtac aatattcctt aaatttatct caatttttat
    34861 tcttccatgg aaagtatgtt tgtatattgg tattgcttta ggtattattg ttactatttt
    34921 tcttttggtt ataacaattg gtatagaaat gacataaatt ttctacgaaa atatcaaaca
    34981 tgacatgaca tgtaataaag tatgtgttaa aattcattat aagaagtagc aatcaagtaa
    35041 ataaatgctg gttgttattt ttttacccac acagtatata ctagtatata ctaagatata
    35101 ctataatata tactgatata tactaggata tatcagtata gaaaagtata taaataactt
    35161 gtggtatttt attaattgta ctaatttaaa aagagtaaat aatatgtgga ggttttatta
    35221 tgagtaacgt atatgtaatg gctttagatt ttggtaatgg atttgtaaaa gggaagatta
    35281 atgatgaaaa atttgtaatc ccttcaagaa tcggaagaaa aactaatgaa aacaatcaat
    35341 taaaaggatt tgttgataat aaattagatg tatcagaatt tattatcaat gggaacaatg
    35401 atgaagtatt actatttggt aatgatttag ataaaactac aaatactggt aaagatactg
    35461 cctcaacaaa tgatagatat gatattaaat ctttcaaaga tttggttgaa tgttctatag
    35521 gattattagc aagagaagta ccagaagaag ttgtcaacgt tgtaattgct actggtatgc
    35581 caagtaatga aataggaact gataaacaag ctaagtttga aaaactttta aataaaagtc
    35641 gtttaattga aattgacggt atcgctaaaa caattaatgt taaaggcgtt aagatagtag
    35701 ctcaacctat gggaacttta cttgatctta atatggaaaa tggaaaagta ttcaaagcat
    35761 ttacagaagg caagtacagt gttcttgact ttggtagtgg tactacaatt attgatactt
    35821 atcaaaatat gaaacgtgta gaggaagaaa gttttgttat aaacaaaggt actattgatt
    35881 tttataaacg aattgctagt cacgtatcta aaaaatcaga aggtgcctca atcacaccac
    35941 gtatgattga aaaaggatta gaatacaagc aatgtaaact taatcaaaaa acagttattg
    36001 actttaaaga tgaattttat aaggaacagg atagtttgat agaagaagtt atgagtaact
    36061 ttgaaatcac tgtaggtaat ataaattcaa ttgacagaat tattgttact ggtggtggtg
    36121 caaacattca ttttgattca ttaagtcatt attattcaga tgtgttcgag aaagcagatg
    36181 atagccagtt tagtaatgtt cgtggatatg aaaaattggg ggaattgtta aaaaacaaag
    36241 tagagcaaga aagtaaataa ttatggataa gaaagaaact aaacatcttc tgaaaataaa
    36301 aaaagaagat taccctcaaa tcttcgattt tttagaaaat gttcctagag gtactaaaac
    36361 agcccacata agagaggcat tgaggcgcta tattgaagaa ataggggaaa accctccaat
    36421 accttcaaaa gaacacacag cgcccttaaa agagcataca gaacctatta aacgtaataa
    36481 agaaagtttt aaagacgcaa tggaacgtaa ggatcaatta aaacaagctg aaatgcctaa
    36541 aatagaagaa aaagatgaag aaatggtaga tattagtatt gatgaccttt aatatctata
    36601 ttccttcatc caattccatt ttttcttctg catttttaac taccttatga aagtctacac
    36661 catagtattc agacattact aaaaatgtat gtaatgctat tctaggtttt ttaccattct
    36721 cgatacgtga aagatgacca gcagtcacac tcaaatcaaa tgcaacttct tcttgtcgct
    36781 tgcctatgag ttgacgctgg tttttaaatt ctaaacaaat gtatctatat agtttttgta
    36841 tacggtattc attcatgatt tatcggcctc ataattttag atatattaat tatattagag
    36901 atttgttatc aaatacattt cattacaagc atataattga cctgtgaggc aacaaaaaat
    36961 ttttaatttt tttaaaatag tgttactatt gaacatagaa aaagacacct aacgcttggc
    37021 ggttgttaga tgtctaaaga gtttaaataa tatgtgttat ttacttttac aatttgtttg
    37081 tatctttatt atatatacaa cctcgataca ttacaagata aaagcaacaa gtcttt
//
