LOCUS       NZ_CP136174             9474 bp    DNA     circular CON 13-NOV-2023
DEFINITION  Acinetobacter baumannii strain ABO21-A049 plasmid pABO21-A049-1,
            complete sequence.
ACCESSION   NZ_CP136174
VERSION     NZ_CP136174.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37654779
            Assembly: GCF_033469325.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 9474)
  AUTHORS   Andre,A., Plantade,J., Durieux,I., Godeux,A.-S., Charpentier,X. and
            Laaberki,M.-H.
  TITLE     Acinetobacter baumannii in Animal ICU
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9474)
  AUTHORS   Andre,A., Plantade,J., Durieux,I., Godeux,A.-S., Charpentier,X. and
            Laaberki,M.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2023) CIRI, Inserm, 50 avenue Tony Garnier, Lyon
            69007, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: SEP-2022
            Assembly Method                   :: Unicycler v. 0.4.9
            Assembly Name                     :: CIRI-ABO21-A0049
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 829x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/12/2023 12:49:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,748
            CDSs (total)                      :: 3,654
            Genes (coding)                    :: 3,603
            CDSs (with protein)               :: 3,603
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 29 of 51
            Pseudo Genes (incomplete)         :: 21 of 51
            Pseudo Genes (internal stop)      :: 11 of 51
            Pseudo Genes (multiple problems)  :: 9 of 51
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP136174.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9474
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="ABO21-A049"
                     /isolation_source="hospital environment"
                     /db_xref="taxon:470"
                     /plasmid="pABO21-A049-1"
                     /geo_loc_name="France: Marcy l'etoile"
                     /lat_lon="45.79387130 N 4.70843765 E"
                     /collection_date="2021-11-08"
                     /collected_by="Maria-Halima Laaberki"
     gene            1..930
                     /gene="repM"
                     /locus_tag="RWV42_RS18540"
                     /old_locus_tag="RWV42_18540"
     CDS             1..930
                     /gene="repM"
                     /locus_tag="RWV42_RS18540"
                     /old_locus_tag="RWV42_18540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004282204.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_000845850.1"
                     /translation="MKTELIVKDNALINASYNLDLVEQRLILLAILEARESGKGINAND
                     PLTVHAESYINQFGVHRNTAYQALKDACDDLFARQFSYQSLSEKGNVINHKSRWVSEVA
                     YIDNEAVVRLIFAPAIVPLITRLEEQFTKYEIQQISNLTSAYAVRLYEILIAWRSTGKT
                     PLITLYDFRQKIGVLDTEYKRMYDFKKYVLDIALKQVNEHTDITVKVEQHKTGRSITGF
                     SFSFKQKKSATQSVGSKRDPNTLDLFSTMTDKQRHLFASKLSELPEMSRYSQGTESYQQ
                     FAVRIADMLQDTEKFRELIPLLKKVGFQ"
                     /name="repM"
     gene            997..1542
                     /locus_tag="RWV42_RS18545"
                     /old_locus_tag="RWV42_18545"
     CDS             997..1542
                     /locus_tag="RWV42_RS18545"
                     /old_locus_tag="RWV42_18545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004918462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_045124962.1"
                     /translation="MKKLSVSELAKLYGYSRQAIYAHINKGNLSKGSDGLIDFAEALRV
                     FGEPQKKDTNVNQSQSINSQNLTEVDLLKRQVDILEKQLNQALFRENQSLERESFYQDQ
                     IEAMQRLLEAPKANMTTFTDQEQSQANVAQVQPEPNIDDPKHDGLTTPENKRIPVPEHI
                     EPEPEKRGFWSRFFRPYD"
                     /name="plasmid replication DNA-binding protein"
     gene            complement(1730..2044)
                     /locus_tag="RWV42_RS18550"
                     /old_locus_tag="RWV42_18550"
     CDS             complement(1730..2044)
                     /locus_tag="RWV42_RS18550"
                     /old_locus_tag="RWV42_18550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005108843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000723215.1"
                     /translation="MKKILYFNFLAIILTYVSLLYQKNILVARIVVDKLEKVEVIAGGF
                     PLQFLIDGETSPVGSISINPLFIFIGMDQFVFLNFFIDYLFWVSILFAFSMIVKKYRIV
                     "
                     /name="hypothetical protein"
     gene            complement(2047..2460)
                     /locus_tag="RWV42_RS18555"
                     /old_locus_tag="RWV42_18555"
     CDS             complement(2047..2460)
                     /locus_tag="RWV42_RS18555"
                     /old_locus_tag="RWV42_18555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005020944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_318591277.1"
                     /translation="MKYSNEKIVKALLLSPLPLLFFTAVLFIVMNQEYSLYSILVVLVG
                     HGLVYLAYCILTVPFSFIFSILLNRYNSLNLLTICIASIIIATPFFILFEWSHTGEISK
                     EWWKMYTDTWTIFMALFPGLCYWLFLINLKDKK"
                     /name="hypothetical protein"
     gene            complement(2988..3932)
                     /locus_tag="RWV42_RS18560"
                     /old_locus_tag="RWV42_18560"
     CDS             complement(2988..3932)
                     /locus_tag="RWV42_RS18560"
                     /old_locus_tag="RWV42_18560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005140915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005140915.1"
                     /translation="MNYLYSSFKLDYLNSECDFLNINLDEDTRLFVDAYAMSRSSNTHM
                     QSGHETLRVFMSETLAGLKNYVKDPAAINSLWVPKCFAEPKGTGIGLAKNGHKGRGSHD
                     VKCQQIITALRHSKAVETGDLEDLEELLLVIEGIGSDTISDITLNIAKKHFIEYTQEKC
                     KKLNIPVSQTKEKIRYFCSVDKKWKSDNFDLPHLEVGLEKTLSYLIFIPNEILEKNMAY
                     GCNYFYTNVATPIYVDQILVAGSSFIYSLKNGTKKVNKKEMRKDDKYKGGKKRMDNFIS
                     DNPKSLKEYRKTVADKRYKKNQDKKKPKNDDSE"
                     /name="hypothetical protein"
     gene            4092..4448
                     /locus_tag="RWV42_RS18565"
                     /old_locus_tag="RWV42_18565"
     CDS             4092..4448
                     /locus_tag="RWV42_RS18565"
                     /old_locus_tag="RWV42_18565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_005265162.1"
                     /translation="MWTVITTDLFNEWLEQQDESTQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGRPLRAFFAFDPLRQAIVLCIGDKGGKKRFYKEMLDIAEQQ
                     YELHISTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            4441..4743
                     /locus_tag="RWV42_RS18570"
                     /old_locus_tag="RWV42_18570"
     CDS             4441..4743
                     /locus_tag="RWV42_RS18570"
                     /old_locus_tag="RWV42_18570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_005140921.1"
                     /translation="MAKTLQELLASRSPESQARIQQMADELLLETQLYLIREELEISQK
                     ELAETLGIKQPSLSAIENRGNDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(4819..5595)
                     /locus_tag="RWV42_RS18575"
                     /old_locus_tag="RWV42_18575"
     CDS             complement(4819..5595)
                     /locus_tag="RWV42_RS18575"
                     /old_locus_tag="RWV42_18575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005140922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005140922.1"
                     /translation="MKLEKISERIFFSTIKMNLVTKEETNVIATGFFVSKSINKDEFVI
                     CLVASKELIDNSIAASLVFHEAIDQVNLDVNEKEKIHIRIGESDWKDMWFSSDKTNDFV
                     IAPIMPIVNFIEGQLDKFCFLQPIDLTSISKGEQLKDISLSEDILFLTYPNEIIQEDEY
                     MPVLGRAKLATALFKDFNGNPEFLIQSPDTSNTSGSPVFILNEGSFMTKNGQVLGNRFL
                     FLGIMNGSISNGLARVIKANLLNSVVDEFVESLIKD"
                     /name="hypothetical protein"
     gene            complement(5592..6068)
                     /locus_tag="RWV42_RS18580"
                     /old_locus_tag="RWV42_18580"
     CDS             complement(5592..6068)
                     /locus_tag="RWV42_RS18580"
                     /old_locus_tag="RWV42_18580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005140931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005140931.1"
                     /translation="MSGFLLTGIIVAALVSIASMGLAVSLLFSKNKELLKQVKEEFFSE
                     DKTSINNAIAMVESEINVSNENKISETSKDISPNDFLELISPFELKTKTGFVSTRFFGS
                     ILATTLDVKIQKTKPYSAQVLRNINQKALDTSPLHEVSRPSTFSDTETFVRRYS"
                     /name="hypothetical protein"
     gene            complement(6672..7184)
                     /locus_tag="RWV42_RS18585"
                     /old_locus_tag="RWV42_18585"
     CDS             complement(6672..7184)
                     /locus_tag="RWV42_RS18585"
                     /old_locus_tag="RWV42_18585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000064854.1"
                     /translation="MSNGTNYFKYIGLEFIKFLIPISITFLTACFFSKLFSSKELFEIY
                     VSAKINAHLTNEFFSILGAITILLGILFMIKSLSGFNVLDKFLTLILEEIPKNITIFGG
                     AITGSIYALSWYSYSYDIVLKQTPMQIFFLGTFFAITFFIYAVALQYLIDQKKIKDSQQ
                     QVNSNNG"
                     /name="hypothetical protein"
     gene            complement(7279..7638)
                     /locus_tag="RWV42_RS18590"
                     /old_locus_tag="RWV42_18590"
     CDS             complement(7279..7638)
                     /locus_tag="RWV42_RS18590"
                     /old_locus_tag="RWV42_18590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000360920.1"
                     /translation="MDKQRVFFCGNYLIEKREKSQIKKNAKAGDVKSMLDLARYYYANK
                     KIKKTIKYADLAALRQGSYTQYEVGIFYFQLEIHYKAVFWLTIAAKNGDLDAIEDIKSI
                     YNINLNFSNNFKDAA"
                     /name="hypothetical protein"
     gene            complement(7747..7887)
                     /locus_tag="RWV42_RS18595"
                     /old_locus_tag="RWV42_18595"
     CDS             complement(7747..7887)
                     /locus_tag="RWV42_RS18595"
                     /old_locus_tag="RWV42_18595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001985218.1"
                     /translation="MSDNIIQLSKPCTLCENRQNVQLFAGLMLCESCQENIRLTNPDMF
                     S"
                     /name="hypothetical protein"
     gene            complement(7887..8258)
                     /locus_tag="RWV42_RS18600"
                     /old_locus_tag="RWV42_18600"
     CDS             complement(7887..8258)
                     /locus_tag="RWV42_RS18600"
                     /old_locus_tag="RWV42_18600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_318591276.1"
                     /translation="MGEKVKTYAVRLDPQVAEFYDQLANSEGIRTSKLFSKILTNDFQS
                     IAVKQQADRIEDLVNRLEKRIDDFEEDNNFSEKYYEDFSGLYFMMLWTLMKNGASNDEV
                     RMMQAKGYSYADDNYKRVK"
                     /name="hypothetical protein"
     ARG             complement(1731..2044)
                     /name="ADC-8"
                     /gene="ADC-8"
                     /gene_name="ADC beta-lactamase without carbapenemase
                     activity"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="26.2"
     Typing          2..930
                     /name="rep_cluster_1254"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.57"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaaaacag aactaatagt taaagataat gctctaatta atgccagtta taacctagat
       61 ctagtcgagc aaaggttaat tcttctagcg atacttgaag caagggaatc gggcaaagga
      121 ataaatgcta atgatccatt aacagttcat gctgaaagtt atatcaatca atttggtgtt
      181 catcgaaata cggcttatca agcattaaaa gatgcttgtg atgatctatt cgcgagacaa
      241 tttagttatc aaagccttag tgaaaaagga aatgttatta atcacaaatc aagatgggtg
      301 agtgaggttg cttatattga taatgaggct gttgttagac ttatctttgc tcctgctatt
      361 gtgcctttaa ttactagact agaagaacaa tttacaaagt atgaaataca acaaataagc
      421 aatttaacaa gtgcttatgc cgttcgttta tatgaaatat taattgcatg gcgtagtact
      481 ggaaaaacgc ctcttataac cctgtacgac ttcagacaaa aaataggtgt actcgatact
      541 gaatacaaac gaatgtatga ttttaaaaaa tatgttttag acattgcatt aaaacaagtt
      601 aatgaacata ccgatattac tgtcaaagtt gaacagcata agacgggcag atcaattaca
      661 ggtttttcat ttagctttaa acaaaaaaag tcagctactc aatctgtcgg atctaaaaga
      721 gatccaaata cattggacct gttttcaaca atgacagata aacagcgtca tctatttgcc
      781 agtaaactct ccgagcttcc tgagatgagt agatattcac aaggtacgga aagctatcag
      841 cagtttgctg tacgtatcgc tgacatgctg caagatacag agaaatttag ggaattaatt
      901 cctttgctca aaaaagtagg atttcaatga cattgttaat tgaaattgtt aagttaacag
      961 tcaagtatta acacgagttg aaaactggtt tatataatga aaaaactgtc agtttcagag
     1021 ttggctaagc tttacggata ttcacgacaa gccatatatg cgcatataaa caaaggaaat
     1081 ttatctaaag gatctgatgg gttaattgac tttgcagaag ccttaagagt ttttggggaa
     1141 ccacaaaaga aagatactaa tgtcaatcaa agtcaatcaa ttaacagtca aaacttgaca
     1201 gaagttgacc tattaaaacg tcaagttgac atactggaaa aacagttaaa tcaagcactg
     1261 tttagagaga atcaatcgct agaacgtgaa tctttttatc aagatcaaat cgaggccatg
     1321 cagcgcttac tggaagcacc aaaagccaat atgactacgt ttaccgatca agaacagtcg
     1381 caagcgaatg tagctcaagt acagccagaa cctaatattg atgatcctaa acatgacgga
     1441 ttgactactc cagagaacaa acgcattcca gtgccggagc atattgaacc agagcctgaa
     1501 aaaagaggct tttggagccg tttttttaga ccctatgatt aaccacgatt atttaactaa
     1561 tatgaataaa gtcgtgaaac tttgattaaa taataagcgt ggaacgtgaa aaatcataaa
     1621 aaaaaagccc accttgggaa ggttgggcaa aaaagaaact acagcgttga attttcaaga
     1681 gaattataac gcatttcgta taaggtgtat tatgttaatt ttaggagatc tatacaattc
     1741 tgtacttttt cacaatcata gaaaaagcaa ataaaatact tacccaaaat aaataatcaa
     1801 taaaaaaatt gagaaaaaca aattgatcca tgccgatgaa aataaataaa ggattgatac
     1861 ttatacttcc gactggagag gtttcaccat ctataaggaa ctgtagagga aatcccccag
     1921 ctatgacttc aactttttca agcttatcta caactatgcg agcaactaat atattttttt
     1981 gataaagcaa agatacataa gtcaaaataa tcgctaagaa attaaaatat aatatttttt
     2041 tcataactat tttttatctt ttaaattaat taaaaacagc caataacata agccaggaaa
     2101 gagagccata aagatagtcc atgtatctgt atacattttc caccactctt tcgaaatttc
     2161 tcctgtgtga ctccattcaa aaagaataaa aaatggagta gcaataatta tagaggcaat
     2221 acagatagtt aataaattaa gactgttata acgatttaaa agaattgaga atatgaagct
     2281 gaaaggtaca gtcaaaatac aataagccaa gtagacaaga ccgtgcccta caagaaccac
     2341 taaaatcgag tataggctgt attcctgatt cattacgata aacaggactg ctgtgaaaaa
     2401 aagtagtggt aaaggagaaa gtaagagagc ttttactatt ttttcatttg agtatttcac
     2461 taatttaatt ctcttattta ttcaataaat aataatacta taacgatttt attggaggtt
     2521 ttttgatccc atttaacata atggcggtta tacgaagtac acttgtatat taatatttaa
     2581 atcaataact taaaaaattc accccgacca caaaatgcac aaaaaatggc ttttgtaata
     2641 agttggtgag tttttaagcg aatctgtaac attttgccag taaatttggt taaaaaatga
     2701 tcaatatcgg agtaagtgcc catttcatat ggatctaggt tccaaaaata tccccaattg
     2761 ctggggataa aatttaggct attttgtacg cctgggctta cgtaaattct ggttctttac
     2821 ggctgtccag gataggtgaa ttttcctatg atcaagtcat caggaacagg atgttccata
     2881 acataaaaca aaaattataa gttattgcac atggatcaga gggtacaaca gcacgatcag
     2941 caacgatgaa aaaccccggc aggatgccgg ggttttttat ttaaagatca ttctgaatca
     3001 tcatttttag gctttttctt atcctgattc tttttgtatc gcttatctgc tacggttttt
     3061 ctgtattcct taagggactt aggattatca gaaataaagt tatccatccg ttttttgccc
     3121 cccttgtact tatcgtcttt acgcatttct tttttattta cttttttagt tccattttta
     3181 agtgaataaa taaaagatga ccctgcgaca agaatctgat ctacataaat aggcgtagcg
     3241 acattcgtgt aaaagtagtt acagccatat gccatatttt tttctaaaat ttcatttgga
     3301 ataaagatta aataacttag tgttttctcc aaaccaactt ccaaatgtgg aagatcaaaa
     3361 ttatcacttt tccatttttt atctacactg caaaaatatc taattttttc cttagtttga
     3421 cttactggaa tattaagttt tttacatttt tcttgcgtat attcaatgaa atgcttctta
     3481 gcaatattaa gagtaatatc tgaaattgta tctgagccaa tcccttcaat aactaacaat
     3541 agttcttcaa gatcttctaa atcacctgtt tctacagctt tagaatgtct taaagcagta
     3601 ataatttgct gacacttaac atcatggctt ccccgacctt tatgtccatt tttagctaag
     3661 ccaatgcccg taccttttgg ttctgcaaaa cattttggta cccataagct attgatagct
     3721 gctggatctt taacatagtt ctttaaacca gctaatgttt ctgacataaa aactcttaaa
     3781 gtttcatggc ctgattgcat atgtgtatta gatgatcgtg acattgcata agcatctaca
     3841 aataagcgtg tatcttcatc tagatttata tttaaaaagt cacattctga atttagatag
     3901 tctaatttga aggaagaata taaatagttc ataaagtcgc tcaaaataaa gtcaaaccta
     3961 tcacacaatt attgttttat gcatacaaat caaaacaatg cgacattgtc tgtcgtttaa
     4021 ttaataacca gtttgtattg tattaaattc atcaatataa tatagactat aatctatatt
     4081 ttggttgtga tatgtggaca gtcatcacga cagatctgtt taatgaatgg cttgagcaac
     4141 aagacgaatc aacacaagag aaagtcctag cggctttggt tgtgctacag cagcagggac
     4201 caagtttagg tcgcccttta gttgataccg tgtatgactc taaatttacc aatatgaaag
     4261 agctacgtgt tcaacatcga ggtagacctc tgagagcctt tttcgcattt gatccattac
     4321 ggcaagcgat tgtgctgtgc atcggtgata aaggcggtaa aaagcgtttc tataaagaga
     4381 tgctggacat tgcagagcag caatacgaac ttcatatctc aacccttgga gatcaatcta
     4441 atggctaaaa ccttacagga attattggct agtcgctctc cagagagtca agcacgtatt
     4501 caacaaatgg ctgatgaact acttttagaa actcagcttt accttattcg agaagaacta
     4561 gagatttccc aaaaagaact cgctgaaacc cttggaatca aacagccatc actttcagca
     4621 atcgagaatc gtggcaatga cctaaagatt tcaacaatga aaaagtatgt tgaagcaatg
     4681 ggtggaaagc tccgtattga tgtagagctt ccaacaggaa aacatatagg attcaatgta
     4741 taacaataaa aatgggagct ataagctccc atttttcact ttgcataacg accattatgt
     4801 taatgagaaa aagcttcatt aatctttgat taagctctct acaaattcat ctactacact
     4861 atttaataaa ttagctttga taactcttgc taaaccattt gagatagacc cattcattat
     4921 tccaagaaaa aggaatctat ttcctaaaac ctgtccattt tttgtcataa aagatccctc
     4981 atttagaata aatacaggac ttccagaagt attcgatgta tcaggagatt ggattaggaa
     5041 ttctgggtta ccattaaagt ccttaaataa tgctgttgcc aattttgctc tgccgagaac
     5101 tggcatatat tcatcttctt gaataatttc atttggatag gtaagaaata atatatcctc
     5161 agataacgag atatctttta attgctcacc cttggaaata cttgttaaat caattggttg
     5221 taaaaaacaa aacttatcta attggccttc tataaaattt actataggca tgattggtgc
     5281 tattacaaaa tcattcgtct tatctgaaga aaaccacata tccttccaat cactttcacc
     5341 aatacggata tgtatttttt ctttctcatt tacatccaaa tttacctgat ctatagcttc
     5401 atgaaatacc aaagaagcag caattgaatt atcaattaac tctttcgatg caactaaaca
     5461 gattacaaat tcatccttat ttattgattt tgagacaaaa aatcctgttg cgataacatt
     5521 cgtttcttct ttagttacaa gattcatctt tatggtagaa aaaaagattc tttccgatat
     5581 tttttctaat ttcatgaata tcttctaaca aatgtttctg tatcagagaa tgtagatggt
     5641 cttgatactt catgtaacgg tgaagtatca agtgcttttt gattgatatt ccttaatacc
     5701 tgagcactat atggcttagt tttttggatt tttacatcta aagttgttgc caaaattgaa
     5761 ccaaaaaacc tagtagaaac aaaacctgtt ttcgttttta actcaaatgg actaataagc
     5821 tctaaaaaat cattcggtga tatatcttta gatgtttcag aaattttgtt ctcgtttgaa
     5881 acatttatct ctgattccac catggctata gcattattaa ttgaagtctt atcctctgaa
     5941 aaaaattcct cttttacttg tttcaaaagc tctttatttt tagaaaaaag taaagatact
     6001 gctaacccca tagatgcaat agaaaccaaa gcagcaacta ttattcctgt gagtaagaat
     6061 ccagacatag ccatctccta tacttttttc atttttgata aactataact aactgactgc
     6121 acaactgcta tacagaatgt caaaaaaaca ttgaacccaa taaaaatatt tgccataaaa
     6181 aaactaaatt ttttcagttc tttagagtaa tttttaccat tcgtaatata gtcatgatat
     6241 tcaaacccta agaatgctgt tgagaaaaca aataatattg ctaatgtgac accaaaaaga
     6301 gaccaaagaa tatgatcctc ttttttaatg attggggcaa agtacgtgat aacaactaaa
     6361 aataaagtat atccaatgac atataaatta aagttgtcta tgctgaaatc cgttactgtt
     6421 gctctatgca ctatatactg aagatagtac ggccatatac ttaaaacaaa atttaataca
     6481 caaagcagta tgaaacatcc aataaaatga cctataaaaa ggcatgcttt aatacctttg
     6541 gtacatttca ttacaaggta tccataaaac tttttttgca attataggga taattactaa
     6601 aacctcaata atattgaatt tttttctcat ataaaatttt atatttaaca taaaatctct
     6661 tatgagaatt cttaaccatt attagagttt acctgttgtt gactgtcctt tattttcttt
     6721 tgatcaataa gatattgaag agcaacggca tatatgaaga acgtgatagc aaaaaaagta
     6781 cctaaaaaaa atatttgcat tggtgtttgc tttaagacta tgtcgtaact atatgaatac
     6841 catgataatg catatataga accagtgatt gctccaccaa aaattgttat atttttaggg
     6901 atttcctcta atattaaggt taaaaattta tctaacacat tgaatccaga aagacttttt
     6961 atcatgaata aaattccaag aagaattgta atagctccta gaattgagaa aaattcattt
     7021 gtaagatgag cattaatttt cgcagaaaca taaatttcaa ataattcttt tgatgaaaaa
     7081 agttttgaga agaagcaagc tgttaagaag gttatagaaa ttggtatcaa aaatttaata
     7141 aattcaagcc caatatattt gaaataattt gttccattag acatgtttat tacccctata
     7201 aataaagcga atgtatccag tgcttgaaaa aactttttta ctttttaaca cgtcttatta
     7261 tttatagggc tatcaatctt atgcggcatc tttaaaatta ttagaaaaat ttaaattaat
     7321 gttatatata gacttaatat cttcaattgc atcaaggtca ccattctttg cagctatagt
     7381 gagccaaaaa acggctttat aatgtatctc gagctgaaag tagaatattc caacttcata
     7441 ttgagtatag ctaccttgtc tcaaagctgc taaatcagca tactttatgg tttttttaat
     7501 ttttttattt gcgtaataat atctagccaa atctagcata gacttcacat cacctgcttt
     7561 tgcattcttt ttaatctgag acttttctct tttttcaatt agataattcc cacaaaagaa
     7621 aactctttgt ttatccattt ctataaatcc tgtttagaat tttgattttt caaaaacttt
     7681 tttcaaaatt ttgttcagca tagaagatcc ccttagctcg catacttctt atttcaggct
     7741 ttttatttaa gagaacatat ctgggttcgt aagcctgata ttttcctgac aactttcaca
     7801 cagcatcaat cctgcaaaaa gttgtacatt ttgtctattt tcacaaagcg tacatggctt
     7861 tgaaagctga ataatattat ctgacattac tttaccctct tatagttatc atctgcatat
     7921 gagtaacctt tagcttgcat cattctaacc tcatcgttag aagccccatt cttcattaat
     7981 gtccataaca tcatgaaata gagtccagaa aaatcctcat aatatttttc agaaaaatta
     8041 ttatcttcct caaaatcatc tattcgcttt tctaatcgat tcaccagatc ctcgatacga
     8101 tcggcctgct gcttaacagc aatagattga aaatcattgg tcaaaatttt actgaataat
     8161 ttactggttc tgattccttc tgaattagcc aattgatcat agaattcggc tacttgtgga
     8221 tccagtctga ctgcataagt tttgactttt tcgcccataa attacacctc ttattaaaat
     8281 caatgtttgt acaaaattaa atttataaaa ttcaactgat tgaataaaaa taataagtaa
     8341 attatgtaca aacctatttg tacataatta atttatttta aaacaaaaac ttatttaaat
     8401 ataatgcttt tttcatgtac aacaatgagt acatagtttt tcttatattt atcaaagtat
     8461 tatatgaaaa aagtgttttt ttgatgtaca actatgagct cagcaaatta ataaataaaa
     8521 tcaataactt atttcaaaaa atgggctttt tgcagcgcag ctttctaaca cacaaaataa
     8581 ttacccaaac ccttacacca taagggtttg aaggttgtca tcgttagatg cgtggtgtgt
     8641 gacaaaaaaa tcccggcatg tgccggatct tggattggaa aattggctaa agtgacgtag
     8701 ggccggtgct tggttttgca tggaaaaaaa gtatttattt cctagtttaa aaaaatgtaa
     8761 aaaaatcaat ttttttgtcc atttatccag gttaaaaatt tcaaaccaaa actttaatta
     8821 tgaaaagctt cacggaaagc gttcaaatgc gatttaagag tctttaccta aaaaacatag
     8881 atttatagcg aaaaacagaa aacagctcaa aaaacgcaaa tgagagcgaa ataaagagga
     8941 attttgactc tagatagatt catagagcga gtgtctacga gcgaactatc aaaatttgcc
     9001 tctggccctt cctgaaaaac attttttttg ccctctttag cctaagaaag cgtaagtttc
     9061 atgcagaaat ttgctcctgg accgagcgta gcgagtaaaa aagttttatg agcgtagcga
     9121 attccgagtt gcttttgctt tttcttaaag tcatgtaagt atttaccaaa aaattgcccc
     9181 gacgaactga gcgcaagcga agttcaatag agtttgagcg aagcgaaaac caagggcaat
     9241 ttttccttcc ctgggctttt aagtatttta aagtttttaa atgcttttag atggtctaaa
     9301 aacctttatt tataacactc ttagagatta taaaacgagg tttaccttgc attaaaacga
     9361 ggtttacctt gcattaaaac gaggtttacc ttgcattaaa acgaggttta ccttgcatta
     9421 agcgagttaa taatatagcc tcgtcttatt aaattaaaaa cataatcttt tcat
//
