LOCUS       NZ_CP135265             7364 bp    DNA     circular CON 07-OCT-2023
DEFINITION  Enterobacter asburiae strain FAHZZU5722 plasmid unnamed3, complete
            sequence.
ACCESSION   NZ_CP135265
VERSION     NZ_CP135265.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37542530
            Assembly: GCF_032301015.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter asburiae
  ORGANISM  Enterobacter asburiae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 7364)
  AUTHORS   Li,C.
  TITLE     Coexistence of blaNDM and mcr-10 in Enterobacter asburiae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7364)
  AUTHORS   Li,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2023) The first affiliated hospital of Zhengzhou
            University, Zhengzhou University, 100 Science Avenue, Zhengzhou,
            Henan 450001, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.10.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/07/2023 07:06:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,003
            CDSs (total)                      :: 4,885
            Genes (coding)                    :: 4,745
            CDSs (with protein)               :: 4,745
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 35 of 140
            Pseudo Genes (incomplete)         :: 97 of 140
            Pseudo Genes (internal stop)      :: 25 of 140
            Pseudo Genes (multiple problems)  :: 15 of 140
            Pseudo Genes (short protein)      :: 1 of 140
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP135265.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7364
                     /organism="Enterobacter asburiae"
                     /mol_type="genomic DNA"
                     /strain="FAHZZU5722"
                     /host="Homo sapiens"
                     /db_xref="taxon:61645"
                     /plasmid="unnamed3"
                     /geo_loc_name="China"
                     /collection_date="2022-03-04"
     gene            complement(join(7209..7364,1..135))
                     /locus_tag="RQP58_RS24850"
                     /old_locus_tag="RQP58_24850"
     CDS             complement(join(7209..7364,1..135))
                     /locus_tag="RQP58_RS24850"
                     /old_locus_tag="RQP58_24850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_094965911.1"
                     /translation="MKDNADKGTGDMFGIKRGRGRPKTGSAKTGAERQAAYRTKQQENN
                     VTVTINRGLLEGLDAQMQAIRDGGSAVVLTSEQAGEILRALRTAEKKQLRG"
                     /name="hypothetical protein"
     gene            334..672
                     /locus_tag="RQP58_RS24855"
                     /old_locus_tag="RQP58_24855"
     CDS             334..672
                     /locus_tag="RQP58_RS24855"
                     /old_locus_tag="RQP58_24855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019820367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_094461467.1"
                     /translation="MPTEQPKRLKTIKVRVTETEWASLRAACPKAQLAEWMREHCLGVV
                     PQQRRTPPPTIDPALLRQVAGIGNNLNQIARRINASPLTTLDKVEYLAALAAVARELEG
                     LRRDRQNP"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            872..>1306
                     /locus_tag="RQP58_RS24860"
                     /old_locus_tag="RQP58_24860"
                     /pseudo=""
     CDS             872..>1306
                     /locus_tag="RQP58_RS24860"
                     /old_locus_tag="RQP58_24860"
                     /inference="COORDINATES: protein motif:HMM:NF015397.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1359..1775
                     /locus_tag="RQP58_RS24865"
                     /old_locus_tag="RQP58_24865"
     CDS             1359..1775
                     /locus_tag="RQP58_RS24865"
                     /old_locus_tag="RQP58_24865"
                     /inference="COORDINATES: protein motif:HMM:NF016710.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_232098442.1"
                     /translation="MAKTFEQTSKQQADDIESSLKPEFERHERAIKEALDSSRQSINDA
                     IQDQQKLIGWLLLKSWGVMLISGLLLLAATSGTLWYQGNLIAERQATLETLGKKGGKLI
                     FNKCEDENGKIRLCIRMNMDEGKFGDDYMIPKGY"
                     /name="MbeB family mobilization protein"
     gene            1779..2012
                     /locus_tag="RQP58_RS24870"
                     /old_locus_tag="RQP58_24870"
     CDS             1779..2012
                     /locus_tag="RQP58_RS24870"
                     /old_locus_tag="RQP58_24870"
                     /inference="COORDINATES: protein motif:HMM:NF016769.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD/MobD family mobilization/exclusion protein"
                     /protein_id="WP_153913308.1"
                     /translation="MTELERHLLNALETLQSEQDRQLSGLQTACESLLRQFETTKKENA
                     SLLGEVKVLRQQCEHLNEQVSSLATQVASLKA"
                     /name="MbeD/MobD family mobilization/exclusion protein"
     gene            complement(2815..3192)
                     /locus_tag="RQP58_RS24875"
                     /old_locus_tag="RQP58_24875"
     CDS             complement(2815..3192)
                     /locus_tag="RQP58_RS24875"
                     /old_locus_tag="RQP58_24875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003821152.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_008786737.1"
                     /translation="MTSRKTTSADTAQCSTTSHDAATDALAMSQSDVAVLAETFRLLGD
                     QSRLKILLQCMHGSVAVGDIAEALDLSQSLVSHHLRLLRGARLVRGERQAKHIFYSIAD
                     QHVSQVLQDMAVHISEDKADD"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(3236..4339)
                     /locus_tag="RQP58_RS24880"
                     /old_locus_tag="RQP58_24880"
     CDS             complement(3236..4339)
                     /locus_tag="RQP58_RS24880"
                     /old_locus_tag="RQP58_24880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003821153.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]; GO:0008324 - monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_315427897.1"
                     /translation="MSQSHAHDHGHDHDHDHDHTPTVTSANERKVLLSFFLIFGFMVVE
                     AVGGVLSGSLALLADAGHMLTDAAALALAYAAFRFGRRAADSKRTFGYLRFEVIAGFLN
                     AVTLFAIVAWIAYEAWERLQAPPVILAGPMMIVAVLGLLVNVLVLWIMTRGETDHVNVK
                     GAILHVMGDLLGSVGAIVAAIVIYLTGWTPIDPILSVLVAALILRSAWKLLAKSIHILL
                     EGAPEDASPEKVEQGLMGAVPGLAAVSHVHVWQLTSGRTMATLHVRPNVDEEARAVVKR
                     VEAVLREQFSIEHATVGIDWNSGTDENVCSLQPTSERQDHSGHDHSGHDHSGHDHSGHD
                     HGNHKHGGGHSHGHDHDHDHSAPGHRH"
                     /name="cation diffusion facilitator family transporter"
     gene            4815..5054
                     /locus_tag="RQP58_RS24885"
                     /old_locus_tag="RQP58_24885"
     CDS             4815..5054
                     /locus_tag="RQP58_RS24885"
                     /old_locus_tag="RQP58_24885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="WP_094965907.1"
                     /translation="MVAAAMRSKRTVSVTLEPSLLERARAAGINLSATLAAALQHEISG
                     SEAERWKRENSAAIQELNRITEEHGLLSDDYRAF"
                     /name="type II toxin-antitoxin system CcdA family
                     antitoxin"
     gene            5054..5362
                     /locus_tag="RQP58_RS24890"
                     /old_locus_tag="RQP58_24890"
     CDS             5054..5362
                     /locus_tag="RQP58_RS24890"
                     /old_locus_tag="RQP58_24890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014839830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="WP_094965908.1"
                     /translation="MQFTIYRNKGNARAYPYLLDVQSDIIGELATRIVIPLFPLAAFTG
                     RPAQRLNPVIIVEGDKYLVMTQDMAAVRQTQLGEEVTGVQESRQLIKDAIDFLMDGV"
                     /name="CcdB family protein"
     gene            5477..5908
                     /locus_tag="RQP58_RS24895"
                     /old_locus_tag="RQP58_24895"
     CDS             5477..5908
                     /locus_tag="RQP58_RS24895"
                     /old_locus_tag="RQP58_24895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019535530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="WP_182947070.1"
                     /translation="MNIPTHLKHKPVLEVINYDQIDGPYANDSDAMGLSIGIAQWNSPG
                     WTDLSAKVWRHTGEKWSRQSEELPLHRVIDLTTLICIAMEYCRNGRLSSSDDFPVSMST
                     DNADLGHHVELMKKELKSGSKYLDESLKRLSLELKRLGY"
                     /name="DUF6530 family protein"
     gene            6070..7056
                     /locus_tag="RQP58_RS24900"
                     /old_locus_tag="RQP58_24900"
     CDS             6070..7056
                     /locus_tag="RQP58_RS24900"
                     /old_locus_tag="RQP58_24900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_094965910.1"
                     /translation="MTEKAFLRNLPHRPYCTDDKSSGLLIRPQATALGYRHIQYNPPPH
                     VASLVFDLDKPDSYHAWQDAGLPAPHWISVNRTNGHAHIGYMLATPVARTSAARQKPLR
                     YLAAIEHVLAKRLGADMGYAGLITKNPTHSDWLTIWHQIEPYSLDYLAEFCPDADLAAY
                     SRRSRKEATGLGRNVTVFDNVREWAYTAIRAHWRPNGYDAWLCAVQAACECTNVFGLEQ
                     GGPLPHSEIKATAKSIARWTWRNLTPSTFADYVDRTHTPEIQAVRGAKGGRIGGKVSKG
                     GGRPSKAASLLPVVLQLKAQGYSNRDIAEDLQISAGSVSNYLRRDRE"
                     /name="replication initiation protein"
     Typing          1194..2221
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="89.244"
                     /coverage="100.0"
                     /evalue="1.3299999999999999e-176"
ORIGIN
        1 gttattctcc tgctgttttg tccggtaggc cgcttgtcgt tctgcccctg ttttggctga
       61 tccggttttg ggtctacccc gtccgcgctt gatgccaaac atgtctccgg ttcccttatc
      121 agcgttgtct ttcatcgtcc taattcccgt cacagtgacc ataaatatta tctgtcactg
      181 tgacacaaaa accattaatc cgcaccctca aaatccaacc catgttaaag tactaagcaa
      241 ggacacacag ggggcccgct tcgcggtcta tcccctgtgg ccttgttcag ggggcaagcc
      301 ccccgaaacc cccgaaaaaa acggaggcca tcgatgccga cagagcagcc aaaacggctc
      361 aaaacgatca aggtcagagt cactgaaacc gagtgggcca gcttgcgggc ggcctgcccc
      421 aaagcccagt tggcggagtg gatgcgcgag cactgcttgg gggttgttcc ccagcagcgg
      481 cgcaccccac cgccaaccat cgacccggcc ttgctccggc aggtggccgg gatcgggaac
      541 aacctcaacc agatcgcccg gcgcatcaat gccagcccgc tgaccacgtt ggacaaggtg
      601 gaataccttg cggcgttagc cgccgtggcc cgagaactgg aggggctacg ccgtgatcgt
      661 caaaatccat agccggggag tcggtcgggg atctggcccg gtggaatacc tgcttggcaa
      721 agacgggaac cggagcgggg ccacgctgga tcgcggcgac cccgagatgg tcagggagtt
      781 gatagacggc agccgttacg cccagcggta caccagcggc gtgctgtcgt tccatgaacc
      841 ggacttgccg agggagacca aggatcggtt gatggacgag ttcgagcaag ccctgttgcc
      901 cggactggac gccgatcagt atgcggtgct gtgggtcgag caccgagaca aagaccgcct
      961 agagctgaat ttcgtggtgc cgaacgtcga actgttgtcc ggcaaacgcc ttcagccgta
     1021 tttccacggg gcggacggcc accggatcaa cgcatggcga acggccatca atggcgactt
     1081 gggattgcac gacccagacg acccaatcaa tcggcaggcc gtgactacgg ccaaagacct
     1141 accccggaac aagctggaag ccgaacaagc cattacaggc ggcttgctgg gcatggctgc
     1201 ggcggggctg gttaaaaacc gggaggacgt gctcaagacc ctgaccgggg cggggttcga
     1261 cgttaccagg acaaccaaga acagtatcag cattgccgac cctgaagggg gccggaatat
     1321 ccgcctaaag ggggcgatct atgagcaaga ttttagacat ggcaaagacc ttcgagcaga
     1381 catcgaagca gcaagccgac gatatagaga gcagtctgaa gccagagttc gagaggcacg
     1441 agcgagctat caaagaagcg ttggactcaa gcaggcagag catcaacgac gccatccaag
     1501 accagcagaa gctgatcggc tggctcctgc tcaagagctg gggagtgatg ttgatctcgg
     1561 gcttgctgtt gctggccgcg acgagcggga cgctgtggta tcaggggaac ctgatcgccg
     1621 agcggcaggc caccttggag acgttgggca aaaagggcgg gaaattgatc ttcaacaagt
     1681 gcgaggacga gaacgggaag atccggcttt gcatcaggat gaacatggac gaagggaagt
     1741 tcggggacga ttacatgata ccgaagggct actaaacgat gaccgagcta gaacggcact
     1801 tattgaacgc gctagagacc ttgcagagcg agcaagatcg gcaattgagc ggcttgcaaa
     1861 cagcgtgcga gagcttgcta cggcagttcg agacgacgaa aaaagaaaac gcgagcttgc
     1921 tgggagaagt gaaagtcttg cgccagcagt gcgagcactt gaacgagcag gtcagcagct
     1981 tggcaacgca ggtcgccagc ttgaaggcat gatcgcgcag cagacggcgc agacgcagga
     2041 ggggttattg gacgaatacc agcaggccca cgcagaacgg gatctctatt tcaatcggaa
     2101 gcacgagcag aaagagatct ccggcttgcc gatagacaag gccagagagt acctacagga
     2161 aggactggag gggcggatag agcggcagca ggtccgcgaa cgggggcgtg gctttgagat
     2221 gtaggggttc tagggatttt ccgtccaaaa acgacaaagt gctctggagg ccacgccgtc
     2281 cgcggcctcc agaggggtat tacttttttg gcgcttcaca tagccagtca caataaatca
     2341 atcacttagc agtctgaatg tcgcatttgg acggaaaatc cctagaaccc cgaagtgccc
     2401 ctttcttgga tgcaggactc cggcccttcc gaagcgctct gcagaaattt gtgtggaggc
     2461 taggcgttac aacgaaggca aggtcaagcc ctttgggttg ccctagcggg caggctgcat
     2521 ggacaaggtg gtgggaaaac cccgcgtcgt cgctgtggcc actccgacat ccagctcacg
     2581 agtgccgttg tgcggttgaa ccggtcggtc ttgtgggtga ttgcgagcgc gggaggctca
     2641 ggcgtccaag ctgccgccgc ccattgctgt gcctgcgcgg catcccggcg cccaggcagg
     2701 gcccgcgatt cagggtgttg cgcccaggcc gcatcgagga cgtccttgag gctaaccggc
     2761 ggcgtgggta ccggcgcctc gcaacctgcc attcgcctgg gtgcttgggc ctggtcagtc
     2821 gtcggctttg tcctcggaaa tgtggaccgc catgtcctgc agcacctggc tgacgtgctg
     2881 gtccgcgatg ctgtagaaga tgtgcttggc ttggcgttcg ccgcgcacga ggcgcgcacc
     2941 gcgcagcagc cgcaggtgat ggctgaccag agactgcgac aggtcgagcg cttcggcgat
     3001 gtcccccacg gcgaccgagc catgcatgca ctgcagcagg atcttcaatc gcgattggtc
     3061 gcccagcagg cggaaggtct cggccagaac agcgacgtca ctttgcgaca ttgcgagggc
     3121 atcggtcgcc gcgtcgtggc tggtggtcga gcattgcgcg gtgtcggcgc tggtggtttt
     3181 gcgggacgtc atggatgcaa atcctcaagt ggagtgcgag ccggctcgcg cggcctcaat
     3241 gcctgtgacc aggagcggaa tggtcgtggt cgtggtcatg gccgtggctg tgcccgccgc
     3301 catgcttgtg attgccatga tcatggccgc tgtggtcgtg cccgctgtgg tcatgaccgc
     3361 tgtgatcgtg gccgctgtgg tcctgacgct ccgacgtggg ctgcaagctg cagacgttct
     3421 cgtcggtgcc cgagttccag tcgatcccga ccgtggcgtg ttcgatgctg aattgctctc
     3481 gaagcaccgc ttcgacgcgc ttgaccacgg cgcgtgcttc ctcgtccacg ttggggcgaa
     3541 cgtgcagcgt ggccatcgtg cgcccggagg tgagctgcca cacgtgaacg tggctgacgg
     3601 ccgccaggcc cggcacggcg cccatcaggc cttgctccac cttctccggc gaagcatcct
     3661 ccggcgcgcc ttccagcagg atgtggatcg acttggcgag cagcttccat gcgctgcgca
     3721 ggatcagcgc cgcgaccagg accgacagga tgggatcgat cggcgtccag cccgtgaggt
     3781 agatgacgat cgcagcgacg atggcgccga ccgagccgag caggtcgccc atcacgtgca
     3841 ggatggcccc cttcacgttg acgtgatcgg tctctccgcg ggtcatgatc cacagcacga
     3901 gcacgttcac cagcaggccg agcacggcga cgatcatcat cgggccggcc aggatcacgg
     3961 gcggcgcctg cagccgctcc cacgcctcgt aggcgatcca agcgacgatc gcgaacaggg
     4021 tcacggcgtt caggaaaccg gcgatgacct cgaagcgcag gtagccgaag gtgcgcttgc
     4081 tgtcggccgc gcggcggccg aaccggaatg ctgcgtaggc cagtgcgagc gccgcggcgt
     4141 cggtcagcat gtggcccgcg tcggccagca aggccagcga gcccgacagc acgcctccga
     4201 cggcctccac gaccatgaag ccgaagatca ggaaaaagga cagcaggacc ttgcgctcgt
     4261 tggcgctggt cacggtcggg gtgtggtcat gatcatggtc gtgatcgtga ccatggtcat
     4321 gtgcgtggga ttgggacatg gggcctcggg aaactgggtc tttgactgtg gctcaaaata
     4381 taacacatga acatgttctc atgtgaattg ttgtacacat ttgtgttcgc gtctcaccac
     4441 ggccgggatg ccgctccggg caattgcctt agcctggctc ggcgaccatt ccccccgcct
     4501 ggcaagcagc cgttgatggg gttctaggga ttttccgtcc aaaaacgaca aagtgctctg
     4561 gaggccacgc cgtccgcggc ctccagaggg gtattacttt tttggcgctt cacatagcca
     4621 gtcacaataa atcaatcact tagcagtctg aatgtcgcat ttggacggaa aatccctaga
     4681 accccatgta gctgccgcgc tgcgcttggc ggccccagcc ccgagcgcga cagacttcgc
     4741 tagtcgcacc cgtcgcaagg gcgtgatatt atcatacacg tgctatcgca cgtgttaatt
     4801 tattggaggt catcatggtc gcagcagcaa tgcgcagcaa gagaacggtc agcgtcacgc
     4861 tggagcccag cttgctggaa cgagccagag cggcggggat caacctgtcc gccacccttg
     4921 cagccgcact acagcatgaa atcagcggat cagaagcaga acgctggaag cgtgagaata
     4981 gtgcagccat acaggagctt aaccgcatca ccgaggagca cggtttgctt tccgacgatt
     5041 acagggcgtt ctgatgcagt tcacgatcta ccgcaacaag ggcaatgccc gcgcttaccc
     5101 ctatctgctg gatgtgcaaa gcgacatcat cggcgagctg gccaccagaa tagtgatccc
     5161 actgttcccg ctggcggcct tcaccgggcg gccagcgcaa cggctgaatc cggtaattat
     5221 cgttgagggg gataagtatc tggtgatgac gcaggacatg gcagcggtga ggcagacgca
     5281 gcttggggaa gaagtcacag gagtgcagga gtctcgtcag ctcatcaagg acgcaataga
     5341 tttcctgatg gatggtgttt gaggctttaa agggaggcag atatttcggc ggttccggcg
     5401 tacaacccca tagacattac caactaaact cagtaatgtt tgtgaaatta gtaaacttga
     5461 taatctgggg ctcgctatga acattccaac tcatttgaag cacaagccgg tactggaagt
     5521 tattaactat gaccagattg atggtccata tgctaatgac tctgatgcaa tgggactgtc
     5581 aattggcatc gcacaatgga actcacctgg atggactgac ctctcagcca aagtatggcg
     5641 tcatacaggc gagaaatggt caagacagtc agaagaacta ccactgcatc gtgttatcga
     5701 cttaacgaca ttgatatgta tcgcgatgga atactgtcgc aatggtcgct tgtcatctag
     5761 cgacgatttc ccggttagca tgtctactga taacgctgat ttggggcatc atgttgagct
     5821 aatgaaaaaa gagctcaaga gcgggagtaa atatctcgat gaaagtctaa aacgactgtc
     5881 tttagagcta aaaaggctgg gttactaacg gggctatgcg gtaacttatt gctcataaaa
     5941 agacaaaccc ccgttatcgc tggaatcttg gcggatctgc gaaaaacggg ggctgtgacg
     6001 aatcacaaga gaagtctacc acatggatca caccaaacaa ccctgcaccg ccaataagcg
     6061 cggtgatcga tgacagaaaa agcctttctc aggaatctcc cccatcggcc ctattgcact
     6121 gacgataaat cgtcagggct gctcattcgc ccgcaggcta ccgcactggg ctatcgccat
     6181 atccagtaca acccaccgcc gcatgtggcg tctttggtgt tcgacttgga taaaccggac
     6241 agttaccacg cttggcagga tgcaggcttg ccagccccgc actggatcag cgttaaccgc
     6301 acgaacggcc acgcccatat tgggtacatg ctggcgaccc cagtagcccg taccagcgcc
     6361 gcccggcaaa agccgctgcg atacctagcc gccatagaac acgttctagc gaagcggctg
     6421 ggggccgaca tggggtatgc ggggctgatc accaaaaacc ccacccatag cgattggctc
     6481 accatctggc accaaatcga gccctacagc ctcgactatc tcgcagagtt ctgcccggat
     6541 gccgatttgg cggcctacag ccgccgcagt cgcaaagagg cgactgggct aggccgtaac
     6601 gtcactgtgt tcgacaacgt gcgggaatgg gcctacacgg cgattagagc gcattggcgg
     6661 cctaatgggt acgatgcatg gctctgtgcc gtgcaagctg cctgtgagtg caccaacgtg
     6721 tttggcttgg agcagggtgg cccgttgccc catagcgaga tcaaggccac ggccaagagc
     6781 atcgcccgtt ggacgtggcg gaatctaacc ccgtccacgt tcgcggatta tgttgatcgg
     6841 acgcatacac cagagattca ggccgtcaga ggggctaagg gcgggcgtat cggtggcaag
     6901 gtatccaagg gcggaggcag gccgagcaaa gctgcttctc tcctacctgt ggtgctacaa
     6961 ctcaaggcgc agggttacag caatcgcgat attgcggagg atctgcaaat ttcggctggc
     7021 agtgtgtcca actacctccg ccgtgatcgt gagtgatcaa aaacaaagcc tatatcagat
     7081 aacagcgccc gtagggcgtt ccttgagccc taaaagcatt caagagagag gatcttggcg
     7141 agggggggta acggcgatcc cgtagggctg tccatcaggc catgtgttcg gcctgtgggc
     7201 agtagctgtt atccccggag ctgttttttc tctgctgttc gtagcgcccg caagatctcc
     7261 ccggcctgtt ccgaggtcag caccaccgca gaacccccgt ctctgatcgc ctgcatctgg
     7321 gcatccagtc cttccaatag ccctctattt atcgtcacag taac
//
