LOCUS       NZ_CP133915            34504 bp    DNA     circular CON 02-OCT-2023
DEFINITION  Escherichia coli strain M23917 plasmid pEco_M23917_34, complete
            sequence.
ACCESSION   NZ_CP133915
VERSION     NZ_CP133915.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37196949
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34504)
  AUTHORS   Martino,F.
  TITLE     New Insights on mcr-1-Harboring Plasmids from Human Clinical
            Escherichia coli Isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34504)
  AUTHORS   Martino,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-SEP-2023) Servicio Antimicrobianos, INEI - ANLIS Dr.
            Carlos G. Malbran, Ave. Velez Sarsfield 563, Buenos Aires, Buenos
            Aires 1281, Argentina
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8-beta
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25x
            Sequencing Technology :: Illumina MiSeq + Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/02/2023 12:37:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 42
            CDSs (total)                      :: 42
            Genes (coding)                    :: 40
            CDSs (with protein)               :: 40
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 2
            CDSs (without protein)            :: 2
            Pseudo Genes (ambiguous residues) :: 0 of 2
            Pseudo Genes (frameshifted)       :: 0 of 2
            Pseudo Genes (incomplete)         :: 1 of 2
            Pseudo Genes (internal stop)      :: 2 of 2
            Pseudo Genes (multiple problems)  :: 1 of 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP133915.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34504
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="M23917"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEco_M23917_34"
                     /geo_loc_name="Argentina: Buenos Aires"
                     /lat_lon="34.5813845 S 58.4095193 W"
                     /collection_date="2018-12-30"
                     /collected_by="Hospital General de Agudos Dr. Juan A.
                     Fernndez"
     gene            join(33854..34504,1..96)
                     /locus_tag="RHT80_RS00005"
                     /old_locus_tag="RHT80_22315"
     CDS             join(33854..34504,1..96)
                     /locus_tag="RHT80_RS00005"
                     /old_locus_tag="RHT80_22315"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_077248209.1"
                     /translation="MGGGVGFVMPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVA
                     DWFYLGMGHWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKW
                     LVPVTKFRVRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRN
                     TIPDKCFPAAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSH
                     TVVSMMLAWAMSAGLAWVFFKKGEQV"
                     /name="PAP2 family protein"
     gene            complement(487..1014)
                     /locus_tag="RHT80_RS00010"
                     /old_locus_tag="RHT80_22320"
     CDS             complement(487..1014)
                     /locus_tag="RHT80_RS00010"
                     /old_locus_tag="RHT80_22320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(1149..1553)
                     /locus_tag="RHT80_RS00015"
                     /old_locus_tag="RHT80_22325"
     CDS             complement(1149..1553)
                     /locus_tag="RHT80_RS00015"
                     /old_locus_tag="RHT80_22325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(1566..2432)
                     /locus_tag="RHT80_RS00020"
                     /old_locus_tag="RHT80_22330"
     CDS             complement(1566..2432)
                     /locus_tag="RHT80_RS00020"
                     /old_locus_tag="RHT80_22330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     gene            3847..4362
                     /locus_tag="RHT80_RS00025"
                     /old_locus_tag="RHT80_22335"
     CDS             3847..4362
                     /locus_tag="RHT80_RS00025"
                     /old_locus_tag="RHT80_22335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            4467..5009
                     /locus_tag="RHT80_RS00030"
                     /old_locus_tag="RHT80_22340"
     CDS             4467..5009
                     /locus_tag="RHT80_RS00030"
                     /old_locus_tag="RHT80_22340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            5006..5257
                     /locus_tag="RHT80_RS00035"
                     /old_locus_tag="RHT80_22345"
     CDS             5006..5257
                     /locus_tag="RHT80_RS00035"
                     /old_locus_tag="RHT80_22345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            5244..5471
                     /locus_tag="RHT80_RS00040"
                     /old_locus_tag="RHT80_22350"
     CDS             5244..5471
                     /locus_tag="RHT80_RS00040"
                     /old_locus_tag="RHT80_22350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            6006..6224
                     /locus_tag="RHT80_RS00045"
                     /old_locus_tag="RHT80_22355"
     CDS             6006..6224
                     /locus_tag="RHT80_RS00045"
                     /old_locus_tag="RHT80_22355"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005058042.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKAGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            6315..6665
                     /locus_tag="RHT80_RS00050"
                     /old_locus_tag="RHT80_22360"
     CDS             6315..6665
                     /locus_tag="RHT80_RS00050"
                     /old_locus_tag="RHT80_22360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            6970..7218
                     /locus_tag="RHT80_RS00055"
                     /old_locus_tag="RHT80_22365"
     CDS             6970..7218
                     /locus_tag="RHT80_RS00055"
                     /old_locus_tag="RHT80_22365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            7215..7562
                     /locus_tag="RHT80_RS00060"
                     /old_locus_tag="RHT80_22370"
     CDS             7215..7562
                     /locus_tag="RHT80_RS00060"
                     /old_locus_tag="RHT80_22370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            7923..8426
                     /gene="taxA"
                     /locus_tag="RHT80_RS00065"
                     /old_locus_tag="RHT80_22375"
     CDS             7923..8426
                     /gene="taxA"
                     /locus_tag="RHT80_RS00065"
                     /old_locus_tag="RHT80_22375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            8430..9659
                     /gene="taxC"
                     /locus_tag="RHT80_RS00070"
                     /old_locus_tag="RHT80_22380"
     CDS             8430..9659
                     /gene="taxC"
                     /locus_tag="RHT80_RS00070"
                     /old_locus_tag="RHT80_22380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            9736..10029
                     /locus_tag="RHT80_RS00075"
                     /old_locus_tag="RHT80_22385"
     CDS             9736..10029
                     /locus_tag="RHT80_RS00075"
                     /old_locus_tag="RHT80_22385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            10026..10241
                     /locus_tag="RHT80_RS00080"
                     /old_locus_tag="RHT80_22390"
     CDS             10026..10241
                     /locus_tag="RHT80_RS00080"
                     /old_locus_tag="RHT80_22390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            10597..11217
                     /locus_tag="RHT80_RS00085"
                     /old_locus_tag="RHT80_22395"
     CDS             10597..11217
                     /locus_tag="RHT80_RS00085"
                     /old_locus_tag="RHT80_22395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            11231..11557
                     /locus_tag="RHT80_RS00090"
                     /old_locus_tag="RHT80_22400"
     CDS             11231..11557
                     /locus_tag="RHT80_RS00090"
                     /old_locus_tag="RHT80_22400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            11576..14323
                     /locus_tag="RHT80_RS00095"
                     /old_locus_tag="RHT80_22405"
     CDS             11576..14323
                     /locus_tag="RHT80_RS00095"
                     /old_locus_tag="RHT80_22405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            14335..15051
                     /locus_tag="RHT80_RS00100"
                     /old_locus_tag="RHT80_22410"
     CDS             14335..15051
                     /locus_tag="RHT80_RS00100"
                     /old_locus_tag="RHT80_22410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            15063..16157
                     /locus_tag="RHT80_RS00105"
                     /old_locus_tag="RHT80_22415"
     CDS             15063..16157
                     /locus_tag="RHT80_RS00105"
                     /old_locus_tag="RHT80_22415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            16184..16333
                     /locus_tag="RHT80_RS00110"
     CDS             16184..16333
                     /locus_tag="RHT80_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_227648764.1"
                     /translation="MSLNWILVFVDKHITSGWSRKRKLITQLVILITGITLFKVLGGIS
                     QSWL"
                     /name="hypothetical protein"
     gene            16672..17358
                     /locus_tag="RHT80_RS00115"
                     /old_locus_tag="RHT80_22420"
     CDS             16672..17358
                     /locus_tag="RHT80_RS00115"
                     /old_locus_tag="RHT80_22420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            17355..18263
                     /gene="virB9"
                     /locus_tag="RHT80_RS00120"
                     /old_locus_tag="RHT80_22425"
     CDS             17355..18263
                     /gene="virB9"
                     /locus_tag="RHT80_RS00120"
                     /old_locus_tag="RHT80_22425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            18256..19374
                     /gene="virB10"
                     /locus_tag="RHT80_RS00125"
                     /old_locus_tag="RHT80_22430"
     CDS             18256..19374
                     /gene="virB10"
                     /locus_tag="RHT80_RS00125"
                     /old_locus_tag="RHT80_22430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            19376..20404
                     /gene="virB11"
                     /locus_tag="RHT80_RS00130"
                     /old_locus_tag="RHT80_22435"
     CDS             19376..20404
                     /gene="virB11"
                     /locus_tag="RHT80_RS00130"
                     /old_locus_tag="RHT80_22435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            20391..22253
                     /gene="taxB"
                     /locus_tag="RHT80_RS00135"
                     /old_locus_tag="RHT80_22440"
     CDS             20391..22253
                     /gene="taxB"
                     /locus_tag="RHT80_RS00135"
                     /old_locus_tag="RHT80_22440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            22262..22684
                     /locus_tag="RHT80_RS00140"
                     /old_locus_tag="RHT80_22445"
     CDS             22262..22684
                     /locus_tag="RHT80_RS00140"
                     /old_locus_tag="RHT80_22445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            22668..22973
                     /locus_tag="RHT80_RS00145"
                     /old_locus_tag="RHT80_22450"
     CDS             22668..22973
                     /locus_tag="RHT80_RS00145"
                     /old_locus_tag="RHT80_22450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            <23086..23280
                     /locus_tag="RHT80_RS00150"
                     /old_locus_tag="RHT80_22455"
                     /pseudo=""
     CDS             <23086..23280
                     /locus_tag="RHT80_RS00150"
                     /old_locus_tag="RHT80_22455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            23284..23856
                     /locus_tag="RHT80_RS00155"
                     /old_locus_tag="RHT80_22460"
     CDS             23284..23856
                     /locus_tag="RHT80_RS00155"
                     /old_locus_tag="RHT80_22460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            23861..26014
                     /locus_tag="RHT80_RS00160"
                     /old_locus_tag="RHT80_22465"
     CDS             23861..26014
                     /locus_tag="RHT80_RS00160"
                     /old_locus_tag="RHT80_22465"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            26011..26217
                     /gene="hha"
                     /locus_tag="RHT80_RS00165"
                     /old_locus_tag="RHT80_22470"
     CDS             26011..26217
                     /gene="hha"
                     /locus_tag="RHT80_RS00165"
                     /old_locus_tag="RHT80_22470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            26235..26699
                     /locus_tag="RHT80_RS00170"
                     /old_locus_tag="RHT80_22475"
     CDS             26235..26699
                     /locus_tag="RHT80_RS00170"
                     /old_locus_tag="RHT80_22475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            26786..27490
                     /locus_tag="RHT80_RS00175"
                     /old_locus_tag="RHT80_22480"
     CDS             26786..27490
                     /locus_tag="RHT80_RS00175"
                     /old_locus_tag="RHT80_22480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            28273..28368
                     /gene="dqlB"
                     /locus_tag="RHT80_RS00180"
                     /old_locus_tag="RHT80_22485"
     CDS             28273..28368
                     /gene="dqlB"
                     /locus_tag="RHT80_RS00180"
                     /old_locus_tag="RHT80_22485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            29031..29678
                     /locus_tag="RHT80_RS00185"
                     /old_locus_tag="RHT80_22490"
     CDS             29031..29678
                     /locus_tag="RHT80_RS00185"
                     /old_locus_tag="RHT80_22490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            29753..30022
                     /locus_tag="RHT80_RS00190"
                     /old_locus_tag="RHT80_22495"
     CDS             29753..30022
                     /locus_tag="RHT80_RS00190"
                     /old_locus_tag="RHT80_22495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            30183..30887
                     /locus_tag="RHT80_RS00195"
                     /old_locus_tag="RHT80_22500"
     CDS             30183..30887
                     /locus_tag="RHT80_RS00195"
                     /old_locus_tag="RHT80_22500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_225236207.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLQIINTLKCIFSMGLRND
                     CLIKFLKYFCIA"
                     /name="DUF2806 domain-containing protein"
     gene            complement(30892..31089)
                     /locus_tag="RHT80_RS00200"
                     /old_locus_tag="RHT80_22505"
     CDS             complement(30892..31089)
                     /locus_tag="RHT80_RS00200"
                     /old_locus_tag="RHT80_22505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_312258705.1"
                     /translation="MGEISVKTGNNARNGGKNSLNRLIRCVCGKKIGPDPRNFNQRVSL
                     GRNDLLIRTFLKKSSTIYLI"
                     /name="hypothetical protein"
     gene            complement(31071..32051)
                     /locus_tag="RHT80_RS00205"
                     /old_locus_tag="RHT80_22510"
                     /pseudo=""
     CDS             complement(31071..32051)
                     /locus_tag="RHT80_RS00205"
                     /old_locus_tag="RHT80_22510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISKpn26 family transposase"
                     /name="IS5-like element ISKpn26 family transposase"
     gene            32181..33806
                     /locus_tag="RHT80_RS00210"
                     /old_locus_tag="RHT80_22515"
     CDS             32181..33806
                     /locus_tag="RHT80_RS00210"
                     /old_locus_tag="RHT80_22515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     ARG             32182..33803
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(1567..2438)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8431..9656
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15064..16130
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          16673..17355
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          17356..18260
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          20392..22250
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cattttttga gccatacggt ggtgtcgatg atgcttgcgt gggcgatgtc ggcagggctt
       61 gcgtgggtgt tttttaagaa gggtgaacaa gtttaatcgc ctttaaaagt aaaaacggtc
      121 gtatcggtta ttacggaacg gttttttcag ttgagtttca aagcgatgat tcatcaacct
      181 ggaaactacc aataggaacg gctttactta cgcctatcgg tcaagaattg atgaaaatat
      241 gcggttccac tccagatatt gcgtatttaa ataaattcct caacaaaata aatgttgaag
      301 gaagccaggt aaaactatca attattaata tgtaaagagg tcgagttacc tgtctgagtt
      361 ccactaacca taattaaaag cgaccgcaaa aactgcccag tgaaaactgt gttgccagta
      421 atcacaaatg cagcaagtac taataaagag cctgttaagc ccgcaaatat gtgggcttat
      481 ttttaattac tcttcatcat cccgcaggaa ctgacaaaaa tcttcgctcc ccatcatatc
      541 gacagtgttt ttaaattcga aaaaagaaat tcctgtcata gcacacacgc gctggataat
      601 cagttttttc ttttgctgtc tgacggttgc ggtttcacca aactggataa cagccaggac
      661 tgtttcatca tatgatttca ggacaaaatc acaggttata ttctgcactt cacggattaa
      721 atcttttaca gcttcctcgc taccatgagg acgaacaaat tcaatgagcc gtattttggg
      781 aaaaacggaa taatcaggta taatattacg tgaaagaatg cctaaaaact ctgattcatt
      841 atttgagagt aagggtactt tagtaaaaca atcaacctcc ccaatggctg taaaagcatt
      901 ggttgtcaaa gctggattat tcttaataaa atcagagaat acattttcag ctgatggcaa
      961 aacaacagca gaattatgtt gttcatctcg ttttttatta cggttaaata tcatttcata
     1021 ttccttttaa aagagcctgc ggcaggcaca ggcaaaaaca tcgtttttgg acaatctgat
     1081 tcaaatgtta acatttgaca tcggattgtc tatcctgcat tgttctttac tgtctgtaag
     1141 atcggcgctc attcttccgg cgttctcccg ataccaaaaa gacggaacgc aaaacggctt
     1201 tcgatccacc attcaaaaat ctgctctgcg caaccacaaa cagttaaggc gatccatgca
     1261 gcaagaacaa cgtaactact gacatctgca cccatgtacc aggcgatagt taaacccatc
     1321 actgcgatac cgcctaaaaa ctgcaacaag aaacgaaatc ccgcaagaat ccccaatgga
     1381 ataacaacaa ccagataaag ggaagcagcc agaaggtatc tgacaggtgt cagcagataa
     1441 aagaacctgg atattttctt tttgtcagaa taaacggcat catttgcaac atcggttgaa
     1501 tgatcattca tgctgtccct gattctttga aaatctacga tattatcctt catattgtta
     1561 tgacctcaat tttcaggtgg gtacatttta tcaaacatat tagtaaactc tgagtcttcc
     1621 ctggtatcgc cctcataacc aattgtataa gagaacttta atttataaac ttttctccca
     1681 attttttctg aaactacgaa acttaagttc tttacttccg tatgtttcat gatttctttt
     1741 actgatttat taagaacatc tcttttaaaa gcaggataat ctggatactt ataatccttc
     1801 accccccccg cccctattgt ataaagattc aattcatctt taagttcatc tattgtcatt
     1861 tcaaaactat tcgcgcgaga attattacta tatattttac gaatgagttg atatagtgat
     1921 gcagcattaa cacttgtcag tcgaacaaca gataataaaa cttgcgttgt ataacgtttt
     1981 tcttcaccaa taagtttaca taaaaatctt ttcgcttctt tcgtaaactt gatccccact
     2041 ctaccttcat tcctgtaata agtagaaaaa acagtcagac tcaaattcat tgaatcaggt
     2101 acattacttt tagtgaactt aaatcccaaa tcactactca gttctaatat ttcatcatgt
     2161 ttcagcttaa gaagcgtcgt atctaatata ttagagccat ccctcaaagc aagataagcc
     2221 gcatcaggct taacctgaac ccatttaatg taatcggcaa ctgtcacata aaatatgtga
     2281 tcatcatcga attcattttt agagtttatc tggcacatgg ctaaaaataa gactttttta
     2341 gcagccatag gcaatgttga cagcgttgaa ttcaattcat ttcgatgtct cacttttgtt
     2401 aagcgagaaa gggaagtctt atttgtcgtc attctcattg ttccaacact cttgataatc
     2461 agactttaac accagaaaca tgatattaca acacaatcaa tatcatgttt aaccgagtat
     2521 cttctcatgt ttcatatctg tgatttatct cacaaaggta atccatgctc aaaatccaca
     2581 ctggattcaa ggcagattaa caacagattc aaaatagatt caccagaaag aacaacgaat
     2641 tagtattctt atgacacatt ttgtggatat caccgaggaa gctctcatgt ttaaccgagg
     2701 aagctctcat gtttaaccga ggaagctctc atgtttaacc gaggaagctc tcatgtttaa
     2761 ccgaggaagt tatcatgttt aaccgaggaa gctctcatgt ttagacaaaa aacacgctta
     2821 aaatcaataa attagagcta ctctaagttt ttaagttttt aagaaaaaca agaaaagata
     2881 aggcttttaa tgcgtgcgaa tattcaggaa ctgtggataa ctcaacaaaa ccagcaacga
     2941 tgatggttcc ttaccataaa tctgtccccc gatgattatt acccgcaagc taaaacaaac
     3001 atcatcaatc attaaaactc ataactttca ataacataaa atcatcaaaa aaatatttga
     3061 tgccttatgt atctcaattt tcaagaccat aaatttgtcc ctagttaact ttaacttatt
     3121 gaaataaata taatattcgt gcgtactgat cctaatgtca catcgcaaaa attccgcttc
     3181 ctcgctcact cagtcgctac gctcctgccg ttcggctgcg gcgagcggta tctcctttct
     3241 caaaaccaga gagattcaga tcatatgatc cgttatttga tcctttttgg atcttccact
     3301 aagaagccct gaatcgcgct ctgccgcttc gttcgataca accatgagga aaaccatgcg
     3361 aaatgaaaaa aatcgcttaa aatgcgattc agagcgtttt agggaggttc tgttagttct
     3421 cctgcattgc gcccgtagtt cgctaacgct cacacgcgca gtacagcgcc ccgccatgct
     3481 gcaatgcacc agggcggggt aaactcgctt gcgctcgcgc taactgcggc attctgcggc
     3541 gcaaatcagc ataatcatgg cctgctggtc agttgggctt tgcagggtga agggatggcc
     3601 tgtgcaccct ggtacgttcg tcagcggctg cgccgcgctt cggggcgatg tggctcctgt
     3661 gctgccctgg tattttcgtt cgccccttcc atccgcttac gcggattaaa aaacgtgata
     3721 acaatcactt atcgagtaaa aaaacgggag aaaacttgca aatacgactt aaaggtcgta
     3781 ttattgtttc atcgaaaggg gaatggcccc tctcacaata gcccagcagg gcaggagatt
     3841 aaaaaaatga atatccagga agcattaaac gtttttggat tatccggcga attaactgaa
     3901 aaagatatca aagcagcata cagaaaagcc gctttaaaat atcatccaga tcgtaacccg
     3961 ttaggggctg aactgatgaa agcggtaaat gcagcttttg atgtattgat ggcaaatatt
     4021 gataaaataa atcagttcca gagcactgat gaacatgcac gatataatta cggtgatgac
     4081 ctggaaaaag tattaaacgt tctttctggt ttatctggtc tggtatttga agtgataggt
     4141 aactgggtct ggattagtgg agaaaccatt acacataagg aaactttaaa agaaatcggg
     4201 tgtaaatggg cggcaaagaa aaaacaatgg ttttatcgtc cagacgaaca taaaagttac
     4261 tggaatcgtg aagaacacac gatagaagaa atccgcgcaa aatacggtac aaccggacag
     4321 cgcagggcga cagggtggca acgcgtggaa accagagcgt aaccagaacg ggggcgagaa
     4381 gcccccgata ttatagccag cccgtctttt ggggcatcga acccaaaaag acgggaacag
     4441 cagccacgta gcaaaaaggg aaacagatga actctttttt tgaacaatat caccctgtct
     4501 ttgaagttgt ctgccgtatc ctggggaacg gctggcgcgt gaacaaactt gatgattgtt
     4561 cgtctcgtat aaaactgacg tcaccgcagt ttaaaaatta ctctgtgcat attcggatgg
     4621 aaaaagaccg cttttctgtg gtggggagtg tggatagtcg ttcctggcgt agtccgcatc
     4681 atgtttgcac gttatccaga aaacggaatc ccgttgatat tgcagccgat atcgagcgaa
     4741 aaattctggt aaatgcttcg caggaggtgt tacaggcgat tgagtatgag aaacaccagg
     4801 tggaaaaaaa ggacgaaatt ctgatcctga aaggtatgtt atcgcaactt gtccagcttg
     4861 aaagctggta tggggcattg acaggcttta aagctgaaaa cggattgaac ggtaaagtca
     4921 ccgaacaggg cgacagttat gatttacaga ttcggggctt gagtatagat caacttgtta
     4981 aaattacagg gtatttgaaa cagttatgag aaaaaataaa ggtgatgtga cttattttct
     5041 tgaaaaagaa ggtgacaatt acaggcttac aaaaaggata aaagccagaa caaatgttaa
     5101 aatcgggaac aaaactacga aaattacatt gtatgatgct gtactgaatg agaatgaatt
     5161 acaacatatt gattttacgt gtgccggatt aagggaagac gatgagacgc cagttaagaa
     5221 tttaattaag gagtttatgt taaatgaaac ccgataatac acctgaaaat gtaaaaaaat
     5281 tacgtttaaa agcaggatta acacaaaagg aatgcagtca tatttatggt gttgggctaa
     5341 gaacctggca gaaaaaagag gaagttaata ctcaaaacag tcaaagtctg tcactggttg
     5401 agtttgagtt tcttttgtta cttgcaggag aacatcctga atacgtgctc tgcaaaaggg
     5461 agtcaaaata aaatgacctg tgatggtttt atattagtac ctggagttgc gctcgtagct
     5521 cgctgacgct cacacgcgca gtacagcgcc ccgccatgct gcaatgcacc agggcggggt
     5581 aaactcgctt gcgctcgcgc taactgcggc attctgcggc gcaaatcagc ataatcatgg
     5641 cctgctggtc agttgggctt tgcagggtga agggatggcc tgtgcaccct ggtacgttcg
     5701 tcagcggctg cgccgcgctt cggggcgatg tggctcctgt gctgccctgg tattttcgtt
     5761 cgccccttcc atccgcttac gcggattaaa aaacgtgata acaatcactt atcgagtaaa
     5821 aaaacgggag aaaacttgca aatacgactt aaaggtcgta ttattgtttc atcgaaaggg
     5881 gaatggcccc tctcacaata gcccagcagg gcaggagatt taaaatgaaa tgctcatctg
     5941 tttttacttc aaccactaat catgttttca cattcgaacg agtaacgctt tgcactatta
     6001 tccttatgca taaggatact ggacaacagt atgttgtcat atttactgat aacaataaaa
     6061 ttcgtgacta taaagccgga attgttcctc agtttggcga acttaagcag agtgatgttg
     6121 atttagtcct tttctacagg gacgaatatg aaaaatattt tgattcatta aaagatggcg
     6181 atgaatgctt gagttttaaa gattttattg agtgtctttg ttaagcatta tgaatgcagg
     6241 ggcatccctg cattttctgg aaatttcaat attgattctg aaattgtcta ttaacatcaa
     6301 tgcaagggaa attcatgaaa acgttaaaac aagccgcaat gcagtttgca tctgatctgc
     6361 gtaataatcg ctgttttaaa gctgcttata atgatgctct gttagagctt gatcgggaag
     6421 atttaaacgc cattgtacaa tgcacatttc tttttgagcc aaaacgaaca ttagccgaac
     6481 ttgataaatt aattaaaaag atagaagtag aagaagatta tgagttttgt gtatcccttg
     6541 ataaaggtaa aggattacac gaagtcagaa catttaaaag tgagcgtgag gcgttggatg
     6601 cttatcgcat tttgactctt tacggataca cagtaactat agaaaagaag gagggtaatg
     6661 actgactatt caaggtgtga tcaggttgtt ccaccaacct gatcacgtta tcgacaatca
     6721 aaactgaatg aggtttttaa atgtcaacgc ggcagatcgt acagcttgct gattcccttg
     6781 tcaaaggctg ggaaaccaga attccggcaa tgaaatttag cgaatgggat caattccggt
     6841 ggtggttaaa ctacttgcaa gggtatgaaa tgttttaaat aaaaaaaggg gctttctgcc
     6901 cctttgtatt ttttgacaaa aatgccatgt gtaactataa ttagttgcat atctataggg
     6961 gatggattta tggggaaaac agataagcta ctggcaaagt ttttaaacag taaaaaaacg
     7021 tttgaatggg atgaactggt cgttttgttt tcctctttgg gatatgtcaa aaaggaaatg
     7081 caggggtcaa gagtgcggtt tttcaatgct gaaatcaatc acaccatatt aatgcatcgt
     7141 ccacatccgg aaagttatat caaaggtggt acgctgaaag caattaaaca gaatctgaaa
     7201 gaggctggat tattatgaaa catttaaaat ataaaggata tttaggcacg gttgaacccg
     7261 attttgaaaa taatgtcctg tatggaaaac tggcgtttat tcgggacctg gtaacttatg
     7321 aggcttctac attagctgaa ctggaacagg agtttaaaac atctgttgat ctgtatttac
     7381 agtcttgtgt ggaggatgga aaggaacctg ataccccgtt taaaggcgtg tttaacgtca
     7441 ggcttgatcc agaactgcat cgtcgggtag cagaaatggc gatggaagaa gatttatcgt
     7501 tgaatgcctt tgttaataag gctctggaaa aagaagtcag caatcatcgc gcaggggctt
     7561 aattgccctt gtttttatgc cctgtaaggg catgggaggc gctttgcgcc ggaagccccg
     7621 cagcgcagcg aggacttaaa aagcgttacg gcttcagccg taacaattcc cagccctgcc
     7681 aggcctgttt tttctttcac aaatctttca gctatacgtt tgcctgatgg tcgaagacga
     7741 aagaatcttt cagcaacgaa atctggacat atgcagcgac gattttatag ccaggcacag
     7801 tgccacatat ggtacaatca atgcaggata gacaatccga tgtcaaatgt taacatttga
     7861 atcagattgt ccaaaaacga tgtttttgcc tgtgcctgcc gcaggctctg ttggggtgac
     7921 ttatgaagat gatagcgttc aggctaagtg atgatgagtt aaaatttgca gaacataacg
     7981 ctattttaag tggatttacc agtatcaatg cttttgctaa gcataacgtg cttaatattg
     8041 aaaccaagcc tgttaacatc ccagttaata atgaaccagc aaagctggta tcagtgcgtc
     8101 tttaccctca tgaaatagaa cttgttaaac gtaatgctgc tcttcacggc atgagcatga
     8161 gcagagaaat tgctattcgt gtgcgtcagt ctttgttaaa gagtgaagtc tgtctttacc
     8221 ctgatgaagt taaggaactt aaaaaactat caactgctgt agatcgtgtt ggtcgcaaca
     8281 ttcattttat cataaaaggt gaaagattct gtacggttaa cgatccagat ttcagaaaag
     8341 acgttattga agtgattgaa ctgtgtaagc aaattgattc aaaacttgaa acgttaacca
     8401 agagtgttgt taacagattt gggtgattta tgggtgtgta tgtagaacag gaataccgta
     8461 ttaaacgcgc taaagggact gggcgtgatc cgaaatctcc taagttatcg ggaagacata
     8521 tacatgccag taaatcggct tttaatcata aagtcagaca tggtgcggac aagaaagcat
     8581 atacctggac acctacaaaa gaagtcactt ttaaaatcac tggctcaggt aaaacagccg
     8641 caggcatcaa aaatggtatt gattacatta cccgtaatgg tgaacttgag gcttactgtt
     8701 atgatggaaa aggttcagag caaacaggga aaggagaaga ctttaatagg gagtttactt
     8761 caactttatc taaaggaaat gattactcca ggacatatcg tggagaaaac atcgatcatg
     8821 tgaaaaacat ggtcttttca ccaccaccag aagctggagt aagcagggaa gacgctctga
     8881 aagctacggt agaatttctt aaagagactt atccaaacca tgctttcgtt gccgtatacc
     8941 atgatgataa agaagatcat cctcatgtac atgttaatat taaacttcgt gatgaagaaa
     9001 caggaagaag attaagactt actaaatctg aaaccaggaa gttcagaaac ggttttcata
     9061 gaaaactgaa aggtatggga tatgatgtta ccgctacctg gaaaaaagat cccgaacgta
     9121 aacgggagat tgagcgatta caggctgaaa atccgaaaag actccggaat gtttacaagg
     9181 tggtggattt tggggagact tcatatcaga ataaggcagg ggaaaaacga acacctttcc
     9241 tcacttatga aactttaaaa ggtggaaaac aggttacgat ttggggtaaa gacctgaaaa
     9301 atcatttcga gtctgaaaag ctccagccag gaacgcttat caaagtaaaa aaactggctc
     9361 ctacgcttgt acgtagtcca atgtttaatg atgatggaac tgttgcaggc tacagggaaa
     9421 cgcatcgcaa taactggcag attgaaaata ttgcccttga gcggaacaga gaacgtcagg
     9481 ttcatgagcg tgaaaccagg cagccggaag agagcgacgt taaaaagcag ctatccagaa
     9541 aacatgagca aggtcacaat atcgggtttg ctcttgaaca cgggtttaca aaggattcag
     9601 aagaacataa aaaactaaga atacagcaag agaggaactg gaaaggcctg ggattttaat
     9661 ttgattttgg cgcaggtgaa caaagcggct actttgctca cctgctgatc acaacaacct
     9721 acgagggagg ttatcatgac tgagcatgat gctatctgca tttctggact tcatcaaatt
     9781 tttagtgatg aagaacattt gagtgagcaa caaaaagaca ttattctgat gtacgcttat
     9841 ggctataccc tgaatgaaat tgctgatttc aaaggactaa agccttcaac tgtcagaaaa
     9901 tatctcgatt ctgtaagagc tgaactggga ggtgtctcgt tggcagggat cagaacactg
     9961 gtactcattc ggactaatgc ccttctcgtg tcaagtcttt ccaggatcag tgagaggggg
    10021 aatttatgaa aaaatatctg ctttttgctt tgccgttctt cgttgttggt tgtagtgaag
    10081 aagtaaaaag tgtggattgg tgggggcagc atcttacgga agctaaacaa aagcaggcag
    10141 agtgtgagaa gtctggctct gattctcaga actgtaagaa tgttaaacaa gcattgttta
    10201 ttcagtctca gaaggatgct ccagtcccta cattcgatta actaatgttt caatcatact
    10261 agagcgccca tatgggcgct tttttttgca tgatcacacg aatcataata tgaccatttt
    10321 gtcaatgtta tttgatcgta ttgttgagca ttgttatttt gcgaatcatg ttcgcatcta
    10381 aaacaaatcc aaaacacact tatagtggat tgattaaatg aaggagaaat cagataagtc
    10441 atcggaaaaa ggggtttatg tcacgataaa actcgatccc aggttgaatg catttatcga
    10501 agagaaaacg aaaacatctt tgcttagtaa gaggaagcaa attatttact tattaatgca
    10561 gagtatgcgt attgatggat atatggagcg ttagctatgg cgtctttatt cccagccttg
    10621 ttgctgtgtg cggcgtcagt tcatccggat acgataaatg atattgcacg ggtcgagagt
    10681 ggcttcaatc cttatgctgt ggctgaaatt attcctgaaa gggaacgcgg tagctatggc
    10741 aaaagtgtta tcagtcatat gcccaaaagt aaggaggaag ctctaacagt tatcagagaa
    10801 attgaaaaca gaaaaagacg ttattctgtc ggattgatgc agattaccag cagtaatttt
    10861 tctttttatt ccacgtccgc agaaaaactc cttgattcgt gtgaaaactt gtctgttttc
    10921 gaaaagatta tcgtggattg ttataaacga gggaggagcc tggagaatgc gcttagttgt
    10981 tactatacag gaaattttag taacggtaag cgaaaagaaa aagaatttaa taatacaagt
    11041 tatgttgagc gaattggtta tacagggaac gaaaaaaaat atgttgtacc aggtacaaga
    11101 agcaacgggg gagaacagcg aaaaaatcgt tcacacaatg cgtcagttat ctggcccgaa
    11161 accattctga aatctgcttt tgttgataac tcacatccaa caaaagttat taattaacag
    11221 gacttataaa atgtcattta agaaatcagt atgtaatcgt atcagttcat ctgtcactgc
    11281 tgtaatgcag cgtaaaaata aggtagttat ggcagtcgcc ggggcaacag ttgcatcacc
    11341 ggcctttgcg gatggatttt caaaagcgga aacactgctg gaaaaggtta aaacagggct
    11401 tagtggcctt tcactggtca cggtgactat tgcctgtctg tgggtcggct acaaggttct
    11461 gtttggtgga agcacgattc gtgaatgctc acctatcatc atcggggcaa ttgttatcgc
    11521 cagtgcggct gaagttgcat caatgatggt taactaataa agcggggacg atagtatgtc
    11581 tacactttat aaagcgatga cacgccctgc tatgtatgtg ggtgttcctg tcgtccctct
    11641 tactgtggtt gcaggggcgt tatttctggc gggggtttat atcagcaagc tgatctggct
    11701 ggctattcct gtcgcggttt ttgttctcag aatgatcact aaacaggacg accacatttt
    11761 taacctttac tttcttaagc tgaaaatgct cggaaactca gtgtgtaatc gtttttttgg
    11821 cgcacgagcg ttcctctccg gacaatatga agctgttgaa attgatgagt ttgttaatgc
    11881 catgaaactg aatgagcgaa tcactactgg taaatatata ccctattcaa gccatgttga
    11941 taaaaatatt gtcaaaacaa agaacggtga ttatgtagcg acatggcaac tgatggggat
    12001 taactttgag tcaatctctg cggagatgtt agaaactatt gactcacagg ttgccactct
    12061 tgttcgttca ttttccggac tgcccgtttc attttataac cattcatgca gggcgagttt
    12121 ttatgatgcc tttaccacaa aatcaggtaa taaatatgct gatataatat cagattgtta
    12181 ctatggttcg atgaagaaaa ataaattcaa ggggaacact ctttacttta cgctgatcta
    12241 cagaccagat gggcgtgtag aaaaactgga aaaacgcaaa aaaagtatta aagaaaagaa
    12301 agatgatatt aacattcatg tgaagagaat gaatgaaatg attaatacat tctctggcgc
    12361 tcttgataaa tttacctgta aacttcttgg tatgtatgag gagaacggaa aggtattttc
    12421 ttctcaactg tcattctata attatcttct gacagggaag ttgcaaaaaa tcagagtcac
    12481 tgattctccg gtgtataacg ttcttggtgg agtggatgta ttttttaatc atgataccgg
    12541 acagatatgc cgcattgatg gaaataaatt ctttcgttct attgaaatta aagatttctg
    12601 tagtgagact gcatccggtg tttttgatgt gctccagtat tctgatgctg actatattat
    12661 tacgcattca tatacatcca tgagcaaatc agaagcattg agtaccatta aacgtgcgga
    12721 aaaacagtta aagagtacag aagatgatgc ggttactcaa ttgcaggaac tggaaaaggc
    12781 aaaaaatgat attgtgtccg gtgatatatc ctttggttac taccatttca cgctaatggt
    12841 aatggcggac agtatcaggg agcttgacga atctgtaagt aaaattacgg cagactttac
    12901 tgacctgggc attattccgg cattgtcaac catgtcattg ccagcggcat attttgccca
    12961 acttccggcg gtttttcatt taaggccgcg tttatctccg gtatcgaatg taaattttgt
    13021 tgaactggca tcattccata atttctacca ggggaaacgc gataaaaact gctggacaga
    13081 agcggttgct attctcaaaa caccaagcaa acaggcgtat tatctgaatt tacataactc
    13141 agtactgttt aaagatgaaa caggtgaaaa gaatcttgct aatactaaag ttataggaac
    13201 ggcgggttca ggtaagacaa tgtttctgtc atatcttgcc tgttcattac agaaatacaa
    13261 taaccccgaa acttttgctg attctgcaaa aaataagaag ttaacgtgtg tctttcttga
    13321 taaggacaga ggggctgaat tatgtatccg aatgcttggt ggggaatatt acaccgtaaa
    13381 aagcggtgag ccgacaggat ggaatccttt tgctctggag gcaacaaaac gtaaccgtat
    13441 ttttgtcaag caactgatgg agattctgtg taccagaaat ggtgaaagat tatcgacaag
    13501 agaaagattg cttattagcg aaagtgttga tgctgtgatg gattttcctc ctggcgaaat
    13561 gcgggaatat ggcattacca gaatgcttga gcatcttatg cagagagatg atcgggatga
    13621 gcaggagaac gggattatcc ttcgtttgtc ccaatgggct aatggtcagg ctcatggctg
    13681 ggtttttgat aatgctaaag acacattcaa tattcagcat gtcaataatt ttggcattga
    13741 tggcaccgag tttcttgatg atccgatggt atgtgcacca attactttct atctgctgta
    13801 tcgcattacg cagcttctgg acggtcggcg tcttgttatc ttcctggatg agttctggaa
    13861 atggctacag gatgaagcat tcagcgactt tgtctataac aagctgaaaa caattcgtaa
    13921 gctgaacggg ctggttattc cggcaactca gtctccggat gaaatactga agaataagat
    13981 ttcacgggct gtggttgaag tatgcagcac cagtatttat ctggctaacc ctgatgccga
    14041 ttacaatgat tatgtggaag ggcttaagct gacaccagaa gaatttaata ttgttaaaaa
    14101 tcttgatcca atgtcgagac agttcctgat taaaaaaagc agtcttaaaa agggggatgg
    14161 taaatcattt tcagcacttg cgacactcga tttatcggga cttggtggat atctgaaaat
    14221 attgtctgcc agtgcagata atctggaaat ttttgaaagt atttatcatg aaggaatgga
    14281 gcctgatgac tgggttcctg aatatctcga acgggcaatc tgacaggtga atttatgaaa
    14341 cgtgtaaaaa cattgatgct gatatcatta ttgacggctt cattttatag tagcgcagga
    14401 attccggttg ctattgatgc cagtccggaa tgggctgttg aagccgcaag atggacagaa
    14461 cgactcaaac aatggtccga aactgcgcaa cattatcaga gtcagattca ggcatataaa
    14521 gaccagttag ccacggcaac aggtataagg aatattgcgg cattcacaaa tgaactaagt
    14581 aatctacaat cagaactgac aaatatttat aagcagggga acagttatat ttctgatttt
    14641 accagtaatc ccgaaggtgc attgagcagc caggctaaaa atctgttcag caagtatgga
    14701 gccttcgata tgtgtaatac gggctatgaa cgtaatgata atctctgtaa agcacggatt
    14761 gtgtcaacgg ctgccagtat tgaacaggga aatgagatca ataagcagtt atcaagtgca
    14821 atgtctcaga ttcagagttt aagtagccga attgaggctt caaaggatat caaagaatcc
    14881 caggatttgg ctaacgcatt acaggcgcag tcgttaaaaa tgcaggcgat aaaaatgcag
    14941 tatgatgtct ggaataataa aaataaagca gatcatgaga tgttggtcac acaagaacaa
    15001 gaggccttta ttaaacagca gaaagaagct gaaccattaa cttttgatta aaaggtggat
    15061 atatggctca ggggtttttc gttaaatata attctaccgt tatggattcg gtagataaaa
    15121 tcagctccag ttatcaaaca caatttgcta atgatattat gtcgttagca acggtatcgg
    15181 ttacgttata tgtactatgg aaaggatatc aaatacttgc cagtaaaact cagacgccct
    15241 tgcaggattt agtatgggat ctatcaaaat ttgcaatcat aatcatgttt ataactaatg
    15301 cggatgggta tttaactgcg gctactgatg cgttgcaagg catgaaagat ggtttttctg
    15361 gaggggtgag tgtctggcaa actttagata acttatggaa aagtacgcaa aatcttggtg
    15421 cggaaatata ctctttagat aaatcaacat atgttaaaga tcaaggtgta gttggtcagt
    15481 ttttaatatg gactggctcg cttattttaa tggctgttag tgtggttgtt tttttaacag
    15541 cagatgtaac gatgaaactc ctgattatta cagcaccgat atttatcttt tgtctcatgt
    15601 ttggttttat tcggagcatg tttaataatt ggttacaatc gttattctcc agtattctga
    15661 cagttctatt tgccagttta gtgattcgga tagcaatgga ttttcaaggg atgatccttt
    15721 cccatgctat tcgtgctgca caaacaggga atgtaaatct tgtatctaca ggtgctatgg
    15781 gctttatggc tgggtttttg ggggctttat tggttcttat agctaaaggt tttgctgtcc
    15841 agttagcagg tgcaggtgtt gaaggtgctg ttcagggcgc agccatgatg gggctgggtg
    15901 ctgctggtat ggctactggt aagtctctga tgcttggcgg tcgtgctggt ttaggttttg
    15961 gcttagggat ggccggaaga acgggcatga attctttatc agggaaagca gggaatctga
    16021 tggggcgtgg tgcgcgaaca gccgctgaat gggcgggtga aaagggatat caggcgctgg
    16081 ctccgacagg tgctttgggg atgaaggcga gaagacttgc atccctggaa aaagcacgag
    16141 cgaggaacgc cgcatgaaaa taatgaaacg ttttttttat gtgatgtccc tgaactggat
    16201 actggtgttc gttgataaac atatcacctc cggatggagc aggaagagaa agctaataac
    16261 ccagcttgtt attttaatca cgggaattac cttatttaag gtcttaggtg gaatcagtca
    16321 gagctggttg tgacatgctt cattattttg tcatgatact ttattttgtc ctaatccttc
    16381 ttttaggagt gtttacctgc ttcgcaggaa taagacttgg tttagggctt gcggggaaat
    16441 ggagaaaggg tatggatctt cgctttttgc ttcttattgg tgggattctt tttcttcatc
    16501 ttggccttta tctcttaaag gtgttcgtga acgcttaata aggtgaattt atgcgatgtg
    16561 tgattctttt gtttttcctg tttcagattt ccggatgtac cacaaggaat aaccttcctt
    16621 ctgatgtttc cggcgaactg gaacccatta accacagcca ggtaatcagt tatgagtgaa
    16681 aaaatcgaaa agaagattga gacagctaaa tccttcgaaa gacaactcta tgcagaaaat
    16741 gaacggtcta agaaaaatgc atggcgtgtt gcagtggcag catcattact gtccttatgt
    16801 cttggggctg caatttgtgt tcttgtgcca ttaaaagaaa aagagcttgc tattgtggct
    16861 gttggcgaaa aaacaggccg tacagaactg attactcagg ttaaacagga aaagatcctg
    16921 caatctgaag cacttgggcg gtattttgta aacacgtata ttactttacg tgaaggttat
    16981 aattatccgt ctcttcagta tgattatgag actgtacagc tatatagctc gaatacagta
    17041 aaggacgatt atcttcgtct gtataacagc gatatggctc ctgataaaat ttatcataat
    17101 aacggttctt acgttgcggt tgaggtcatc tccaatatta tttctgacgc aaccgcgcca
    17161 gataaactgg cctctgtgcg ctttaaaaaa acgacgagaa acttcacgac cggacaggtt
    17221 tcagtttcat actggacggc tcgtgtgaca tatcgttttg aaccagaaaa gtcggttaaa
    17281 agttccagtc gtgagcttaa tcctctcggt tttactgtaa ccagttacca gacagatcgg
    17341 gaagtcaggg gggaatgatg aagaaattat ttattgctac atgtttattg cttcctgggc
    17401 ttgtgtattc agcagcgact ccgttacctt ctggatttga tgcaaggatg cagactgtga
    17461 gttataacgg tgcgaatacg accgttatcc ggtcaaagac aggatttctc acatcagttg
    17521 tttttgatga aggtgaggct gttatcagtg caaaggctgg ttttcctgcc ggatgggaaa
    17581 tcacaaccga tgataatgtt gtttacatca atccgcgtcc cgttgttcag gaacaggaag
    17641 gcgatgaagg cgaaaaactg aaaaaggttt tccagccaac agaaaaggaa tgggatacga
    17701 atctttttgt cagaacaaca aagcggattt acagtctgga tctaatcctt ctgtcagaag
    17761 aaaaacaagc gcaacctgct tatgttgtac aattccgcta tccatcagaa atagcgaaaa
    17821 agaatgcaga agaagtaagg ctggcaaaag aaaaacagga aaaactcaga cagaagaaac
    17881 tgatttctga aagttttgaa aaagccgatg cgcctaaaaa ctggaattat ttcatgcgag
    17941 tcaatgaaaa atatgacagt cgtcgtatcg cccctgattt tgcttatgat aatggcatat
    18001 ttaccttttt aggttttaac tcagggaaag tattcccagc tccatttgct gtaagagatg
    18061 gtcaggaaca gacacttgct tttaatgtgg aaacaaaagg caagtataaa attatggtta
    18121 tccacaacgt taatgacaaa tttgttttac gctatggaaa cagcgttgtt ggtgttgtga
    18181 ataaatcttt cggaaaagta ttaaccgacc agaggaatac atcttctcct gcggtagaac
    18241 gtgttgaggt gaataatgac tgatatgaaa aaaacagatg atttagttga tgatgcgaat
    18301 cagtcaaagc tggaaagtaa acccgttcat gatatcggtg atatcaggaa caaaaataat
    18361 cgtatgcgtt ctggctttct gtttggtctg atggctgtat tagttattgg tatttttgcg
    18421 ctgaaaacat ataaaaatta ttttgcagat gaccagcaga aagcatcaga atcaacaggc
    18481 gataccagca tttctcaggt aagtaaaatc cgtactggtc ttggtcagaa ttttgaccct
    18541 gttgagaaca aagcaattat caatccaggc gctactggtt ctggtaatac tgtttctgac
    18601 ggtcataaag aagtgccaca ggaggggttc aggaaatatt tgtcaatacc tgttgctggt
    18661 cagggaggga gtcagactgg cgcgagtggc agcagcagga catcgcagac atcagagcca
    18721 caggaagaaa ggaaagaatc aaaagaaaat gtgcctggta aatcaggaat gaaagtaact
    18781 gcgattaatc tcgatcctga tctctatatt gaggaaaaca ggcttatacc gtgtgcttta
    18841 accacacgct ttgtttctga tgttgcaggt cgtatcagtt gtgtttttac agaagatgta
    18901 tggagtgcta atcaccacac aaaattactg gaacagggaa ctaaggcttt tggtcgttac
    18961 cagaccggaa cgctgaatca tggacagggc agaatgttcg ttatgtggga gcagttgcgg
    19021 acgcctgata ataaacgaat cgatatggta aatacagcag cagctggtcc cctgggagaa
    19081 gcgggcattg atggatggat cgattctcac ttctgggagc gttttggtgg ttctcttatg
    19141 ctcagtatgg ttcaggatgt agcggcggcg gcggcggata atgcacctgg taaagatcgt
    19201 aatgtggatt ataccgaaaa ctcacgacag gcaatggctg aaatggctaa agtcgcactt
    19261 gagaattcga taaatattcc tccaacaatg tataaaaacc agggtgacat aatcactatt
    19321 atggtcgggg aagacattga tttttctgat atctatgagt taaaggtaaa atagtatgag
    19381 tggcgttatt cctgtcagca ttagcaataa atcgctcgat ttttataaaa atcaagtatt
    19441 ccagtctttt cttgatattg aagggctaac agaaattgct gtcaaccgtc ctggtgaaat
    19501 ctggacggaa attaatggtg actggacatt ccataataat gacagtgtga cctttgattt
    19561 ttgtaaacgt ttttctcata cgctggcatc atttcgggga gatgaaatcg gcgagaccaa
    19621 gccattactt tcagcaacac tggaatcagg agaacgtgta caggtcgttt ttcctcctgc
    19681 atgtgagaga aatactattt caatcactat acgtaaacca tcgacacggc agataacaca
    19741 taaagaatat gtggcgaacg gtttttatga ttatgtccag tcaggaaaaa aacacaggac
    19801 atacgatgat gagcttcttg atttattcag agcgagaaat atcgctgctt ttatggagct
    19861 tgccgtagca gcagggaaaa ccattgtatt tgccggagca acgggttccg gtaaaacaac
    19921 ttatatgaag agtcttatcg atttcatacc attgaataca cggctgatta cgattgaaga
    19981 tgcagaggaa atcaaatttt ttatccataa aaattatgtg catctttttt acccttcgga
    20041 atccggcagt gattccggct ctatcataac agcagcgaaa ttaatcaaat cctgtttgag
    20101 gatgaaacct gacagaattt tactggcgga aattaaaggt ggcgatgcct gggattttgt
    20161 gaaagttgct ggttctggtc acagtggaag catgacgtcc attcacgcgg cctcggcaaa
    20221 agatgccatc attcagatgg tgacaaaatg ttatcagaac agagaatgtc agaatcttcc
    20281 ttttgatgtt cttcgtaaaa tcattatgga cagtattgat attgttgttc atgtaggcag
    20341 ggatggtgtt gtcaggcata tgagcgacat ctattacaaa ggggctgaat gtgaaaactt
    20401 ttaataagtc gcaatctgtt tttatattcg ctgttatgct tgttgcggca tggtttgcag
    20461 gttcatttat tttctttgtg ctttacttca gccagataaa gaatctgaaa ccattgaagg
    20521 ctgtgttcag atccattgat gcgtacagga tggatatttt tacagacagc cttactttat
    20581 ctgttgtgac tacggatatc agagttttag cctttgttgc acttggagca ggatttgtcg
    20641 tgtctcttat catccctgtt gcggcgttga taaaactgaa cgagaagaaa gaaaatattt
    20701 tcggtgatgc gcgatttgca acaattaatg atattcgtga gtctaacagt ttcacgcttg
    20761 acggtgacga aaaagacggg attatcgttg gtataaaaga caagaaaatc atacgctatg
    20821 tgggagcagc attcagtgct atgggagccg gaacaagggc tggtaaaggt gctggtatag
    20881 tcatcactaa tcttatgaag tactggtgga gtgttattat tctcgatcca aaaagggagt
    20941 gttttaatat caccagtctt atcaggaagg tgattttagg tcatgaggtt tataaatttg
    21001 atccctttag ttcggtaacg caccgcttta accctttgta ttatgtcagc atgggaacga
    21061 gtgaaggttt taatcagctt gaaaatcttt cgttgattat ttacccctat aagacagatg
    21121 gtgcggatgc tggtagctat cttaataaga cggcgggtgg tgtttttaaa tcttatgctg
    21181 tcgctttatg gtttatgatt aagaatgata aggctggact aaaaacgctt gatattgagc
    21241 ctgtcttctc aatgtctaaa attaatcagc tttttgagcg tgcagaaccc gaacatcttc
    21301 tttcattcat gaatgatatt cgttcagaat taagggggaa agacaaaacg cttgctgata
    21361 ttggtgtcgc tggccttaag gcattcattg agatggagga taaaacaaaa gcacaactca
    21421 aaagcaactt tcttaatgga ttatcaccgt ttgctaaccc caatgtggca aatgctactg
    21481 atggaaatga ttttgatttg cggcaggtgc ggaaaaagcg gatgacaatt tatttctgta
    21541 tttctggtga taatgccagg ttggctgaaa aaataacaaa tattttcttt cagcttgcta
    21601 tacaggtgaa tcttgaaaag atgccaacgg atgatccgga aataaagcat gactgccttt
    21661 ttctactgga tgaattcccg tcaattggtg ctgtagatta catcaagagt aaatctggtc
    21721 tcattgctgg ttacaagctg aaattgttga ttgtttacca ggtcggctct cagcttgagg
    21781 aaatctacag ttatgcaggc agtaaaacat tactggcaag tgcaccctgc aaaattgttt
    21841 attccgcttc tgatgttaaa gatgcgcggg agttatcaga agcgatgggg acacgaacag
    21901 taactatcgg ttcgaaaagc aaaagtcgta gtcgtggagg aacatcgaga tctgaatcag
    21961 aaagccttat tgagcgtcca ctggtaacaa caaatgaact acttacactg aaatttagtg
    22021 aagaaatcct ggcaatgaag ggagaaaacc cgattcgttg tgaaaaggca ttctactatc
    22081 tcaatgagta tttctttggt gactttgtga aggttgctcc ggaacttgca aacattttcc
    22141 ccaggaagaa aggaaagctg gttatgcctc cacagaaagt atttgaaaat gaaatcgtcg
    22201 caaaagggta tctggtagta aaagatgttc ctgatctcga taaagcggca taaaggagaa
    22261 catgatgaag aagttagtgt ttttattgat ttccattctt gctggttgtt catcaccgcc
    22321 agagccaaca cccgtgcagt ttgaaaaggc aaatgaagtg atcaatccct cattgccata
    22381 tgtccccgat tttcacggtg tcataaagtc agacgttagc ggtaaaggat gggtttatga
    22441 gatcacttcc ttatccggag tacaggccag aacgccgacg ttttattacg ctctggctca
    22501 tgcggacagg attgtagtga caacacatga tgctgggctg tggtttcgaa tcagagatct
    22561 gttgaagatg gaaggggcaa cagcagtcgt ggaatggcga aacgagaaaa gttttttacc
    22621 tgaacaggta aaaatagttt tcattaaagc acaaaatgag gtgaaaaatg actggaaaaa
    22681 atagagtggt tttaccagcc ttgctggcgt taggattaat atcaacaaat gctaatgcat
    22741 ctgacccttg cgcttcggta ctttgcttat atggaaaagc agtcgggcaa ggtggaggga
    22801 gtgaatgcag aagtgctgaa aaggattttt ttaatattct gaaaaagaaa aaaggaagca
    22861 ttcgctggag taaaactttt gatgcccgta aagcatttct gaatcagtgt tcaacggctg
    22921 atcctgctgc tatatcaaaa atcatgagta agtttggtcg tgtcagaggt taattaaaac
    22981 ctgataaccg cgccaacggg tatcagggta ctgcaagtat cacatttcgc gccaacgaaa
    23041 tgtgatgatt agttacaatc actgaggtta gaaatgaaag taaccaaatc tattatagct
    23101 attttattgt gcttatctgc tggtagtgca taagtggatg taataaaaaa tgctcgtgcc
    23161 tttttgaaag gaaccctcga tctgagcgtt caggaagcag atgaagatat agaggaaagg
    23221 gaagaacttt ataaaaagaa cggggcacaa cctgactatt taagttacct ggaggattaa
    23281 cacatgcaat atgcattgtt tgatggattt gaacgaaagt ttttgctgga tgctcttgaa
    23341 ttcggtgttc tgaaggactg gaaagaaaat ccggtaaaag aacttcctga tattgatgaa
    23401 tctgctcacc ccttccatat ctgttatggt ggatatttat taaaccctgg tgtttcagat
    23461 tcagatatta gcagaaaaat aaaagaccag gcaggattct ggctggcagc tattgatgat
    23521 acccgcatgg attgtcattc aatagcttat tatgatattc acacactccc tctgatttcg
    23581 tgtggtcatc aaaagatagt tccttttgcc gcgttaataa aagctgatga atgcatcatt
    23641 tcaaaaattg cttcgtattc tggttttgct gtaacagcct ttttgagaat taaagagtgg
    23701 gatattgcaa ctaatatact taaccgtgag ggaatttttg cctttaatgg ctgtgagcgc
    23761 agattcagag tagtaagtaa agataactgg caacatacag tatcggaaga acgcgctatc
    23821 cgttgtgcca aaagattaat tcaatgtaaa ggataacaaa atgagacttt ttatcgcaga
    23881 aaaacccgca gtagcaaatg atattgttaa ggcacttggt ggcaatttta cccgccatga
    23941 tggctggttt gaaagtgata acgccattgt gactaactgt tttggtcata ttatcgaatc
    24001 acaaccgccg gaaaactata atcctgaata caaagcctgg aaggttgaaa cgcttccttt
    24061 acgtctttat cccgtgaagt atcagcctgt tgaaagtgca gcaaaacagg ttaaaacgat
    24121 tctcgaactt atcagacgtg gagacgtgac tgaaattgtt cacgctggcg atcctgatga
    24181 tgagggacag ctactggttg atgaagtcct ggaatatgca ggcaacacaa aacccgtaaa
    24241 gcgcgttctg attaacgaca acacgcttcc ggcagtgaaa aaggcactgg caaatcttaa
    24301 agacaatcgt gatttcaaag gactttacct taaggcgttg gcgcggtcag ttgccgatgc
    24361 cgtctatggc ttctctatga cacgtgcgta caccattccg gcaaaagcca gaggatatca
    24421 gggcgttctg tctgtcgggc gcgtccagac tcccgttctt ggcctgattg tgaatcgtac
    24481 ccgtgctaac cagaaccata aatccagttt ttactacacc atgaccggag tctttcagcg
    24541 tggtgctgat gttatcaggg cgaactggaa gccaggggaa tttgctccgc tgacagaccg
    24601 taaattactt gataaagcgt gggcagacgg aacggctgca tcccttgcag gaaaaccggc
    24661 tacagttgaa gcagcagcaa ctgatgataa aaaaacggct gcgccgttgc cgtttaatct
    24721 ggtcagactc cagcaataca tgaacaagaa gtttaaaatg acggcacaaa aaacgctgga
    24781 tattacgcaa caactacgcg aaaaatataa agcaattacg tataaccgct ctgactgctc
    24841 atatctttca gatgaacaat tcagcgaagc gccgcaggtt atcgatgccc tgaaatcagt
    24901 ctttcctcag tcgctggata ttgattctgc acgtaaaagc aaagcgttta acagtgcaaa
    24961 ggtgactgcg catactgcga taatcccgac cgccagtgtg cctgatgtta acgcactcag
    25021 caccgacgag cgcaatgttt acctggcgat cgcacaacac tatcttgttc agttcatgcc
    25081 tgaaaaagca taccaggaag tatcggttgc cattcagtgt ggtgatgagt cgttctatgc
    25141 ccgtgccaga aaaacaactg acagcggatt tgaggcgttt cttggcgcgg aaaccacaga
    25201 cgaaggtgaa tcagaagata atgatgattc cgcttttgaa ctgctctgta aaattcgcac
    25261 aggagaaaca ctgacgacaa aagaagttat tgttaatgag aagaaaacaa caccgccgcc
    25321 gttattcacc gaagcctcct tgcttgctgc gcttgttcgt gtcgcggatt ttgtcactga
    25381 tccaacaatt aaaaaattgt tgaaggataa ggataaagac aaaaaagatg aacatggtgg
    25441 cattggtacg ccagctaccc gcgcagccat tctggaaacg ctgaagaaaa gaaactatat
    25501 cacgctggaa aaagggaaac ttattcctac tgataccgga tatgcgctta ttgatgccct
    25561 gcctggtata gcggttaatc ctgatatgac agcattatgg tctgaaaagc aggctgccat
    25621 agaaaatggc gacctgacgg ttgaacagtt tattaatgat ctgtacggtg aactgacagg
    25681 catgatttct gatgttgacc tgggcgagat gaagattgaa cccgctgcgc cagcagggca
    25741 gtttcaacgc ctggactctc cctgcccttc ctgtggtaaa catattgtta tcaggccgaa
    25801 aggttatttc tgtaccggat gtgaatttaa aatctggagt gagttttctg gtaagaaaat
    25861 cacccaggca caggccgaaa aactggttaa atcagggaaa accgatttga ttaagggatt
    25921 taaaaagaaa agtggtggaa cgtatgatac agttcttgtc cttgaggata agaaaacagg
    25981 gaagctgggt tttccggcaa gggctaagaa gtgaaaacaa agcaggaatg gctttttcag
    26041 ttaagaaaat gtacatcaag agatactctt gaaaaagtta ttgagattaa ccgttacaaa
    26101 ctgcctttat cagaatcaga ggcattttat tctgccgcag atcatcgccg agcagaactg
    26161 gtgatgaata aactttatga taaggtgcct tccggcgtct ggaagtacgt acactaaata
    26221 agaggattaa ttatatgagc gaactgacta aagaagatga atacggcatt atcagccgta
    26281 ctatgatgaa tattcgttca ttgcgtgttt ttgcccgtga gattgatttt gagcagttgc
    26341 tcgaaatgca ggaaaagctc aacgttgtta ttgaagaacg tcgtgaagat gctgaacgtg
    26401 aagcggctga acgccaggaa cttgaagcca aacgtcagca ggccattgaa tacatcatat
    26461 ctttaggtct tgatcccgaa tcactccttg ctcctgtaac agcagataca gtaaaaacca
    26521 ggcggaaagc caaaggcgga gtaagaaagg ctaaataccg ctttaaggat gaaaatggcg
    26581 agatcagaga atggtctggt aatggcaagc gtccgcttgc tttacagaag ctgcttgatg
    26641 aggggcattt catggaagat ttcctcattg agaaaactaa gccggaacag gcagaataac
    26701 ccgccaggta tacatcacac agggcactgt tgcaaatagt cggtggtgat aaacttatca
    26761 tccccttttg ctgatggagc tgcacatgaa cccattcaaa ggccggcatt ttcagcgtga
    26821 catcattctg tgggccgtac gctggtactg caaatacggc atcagttacc gtgagctgca
    26881 ggagatgctg gctgaacgcg gagtgaatgt cgatcactcc acgatttacc gctgggttca
    26941 gcgttatgcg cctgaaatgg aaaaacggct gcgctggtac tggcgtaacc cttccgatct
    27001 ttgcccgtgg cacatggatg aaacctacgt gaaggtcaat ggccgctggg cgtatctgta
    27061 ccgggccgtc gacagccggg gccgcactgt cgatttttat ctctcctccc gtcgtaacag
    27121 caaagctgca taccggtttc tgggtaaaat cctcaacaac gtgaagaagt ggcagatccc
    27181 gcgattcatc aacacggata aagcgcccgc ctatggtcgc gcgcttgctc tgctcaaacg
    27241 cgaaggccgg tgcccgtctg acgttgaaca ccgacagatt aagtaccgga acaacgtgat
    27301 tgaatgcgat catggcaaac tgaaacggat aatcggcgcc acgctgggat ttaaatccat
    27361 gaagacggct tacgccacca tcaaaggtat tgaggtgatg cgtgcactac gcaaaggcca
    27421 ggcctcagca ttttattatg gtgatcccct gggcgaaatg cgcctggtaa gcagagtttt
    27481 tgaaatgtaa ggcctttgaa taagacaaaa ggctgcctca tcgctaactt tgcaacagtg
    27541 cctcacacag acatacacat aggtatgtct gtgtgacata cctatgtaca gtgccagatg
    27601 gcgttgctac gtgaaaaata acctacccta cccctgcttt tttcgcagat tttacgtagc
    27661 acaccgttgc tatagcattc atctaaaaag ctgaatgtcc ttttctgtcg ctgttgcatt
    27721 ttaattcact gaaaaatatt gagtaatgaa aatgccggta acgcgtcaag ctgttggcca
    27781 acgcgacagg cagtattgga agcaacaaaa aaaatgaaag aaaaatccct caaatgaagg
    27841 agaaaaaacg gaactacagc cgaacgacag gcacaaaaaa acccgactgg taatcgggct
    27901 tttttgcgtt ttccagtctt gagttggtgg ctctgaccgg agaaggttac tctacaccta
    27961 acgtttacat tttattcact atggtgctgt aaagcaacta aatgtggtta aggaaccaca
    28021 tttagtggtg taacgggtgt tttgtgtagc gtataatcag tcagttagtc atgtagttgg
    28081 cttgcaatcc tgctgttccc gtatctgcgg gtatgaacga ttttaaagtc ctggctggat
    28141 aaacaggtgg tgctgtattc ggtgctctgg caggaggagg tcactctaca cctaacaatg
    28201 cgagagagcc gttgtgacag gcagtgtatg agcaagcaac ggtgatttcc tccagtttta
    28261 ctggagaaac ggatgattaa tatgttaatc atcgttctca gagctgtggt cgccgttgca
    28321 aacgcgctga ttgcagttct ggaactgatc cgccaattca tcgattgatg acaacggaaa
    28381 cgtaactaag ggcaggaagt gaaccgcttc ctgcccttta acaaaaaagg aggatttatg
    28441 gattttatga gcattttggg gcgctgttta cttcttcctt tccctgttgc gatgtttgtc
    28501 ggttgcctgt ttcctggcat cgatgatcgc ttatccggaa tgcttatgag tgttgctgtg
    28561 ggatgtttat cgtggtatgt caccagaccg aagaaccgac agacaaaggc cgcgtaagtg
    28621 gcctttaatt gggataccct ttagttacaa cattctaata gctcattcca tcctccgctc
    28681 atccagcaaa cataacctcc ctgcccctcc ccactacaga aagtggcgcg ccccgcccgt
    28741 acgggcggaa tctaatcgct taattttgaa tgttgtaact aaacatactc attgctgtat
    28801 tgccacaagg tttcgcagca agggaggata ccgaaagtaa cgctgtcact tttgctttca
    28861 agtgaccaac caacgggtac atcacactga catacaataa tgtatttctt catgatgtac
    28921 atcattgtaa ttcattgtga catacactat agtatgtcca tgtgacatac gcatgcgtac
    28981 atcacataga aatacacatg agtaaatcac tgtgacatac aaggggtact atgattatcg
    29041 taatcggtgg tgataaaggc ggtacaggta aatcacatct ggcaaccaac ttaactgttt
    29101 gcctctcaca acagggaaag agaacggggc ttgttgaaac agacctgaat ggctcgacca
    29161 aaaaatggaa taaacgcaga gaacaggccg gattaccgcc cgtcgcatta aatgaagcct
    29221 atggcgacat cagtgccaaa ataacaaaaa tggcagatgt agcagaaatc ctcattatag
    29281 atactgccgg atatgacagc acggagttca gaactgcact aaaagttgca gacattgtga
    29341 ttgtcccgat cgacccgctt gcccaggtgg aagcagacag tcttcagact gtgacaaaaa
    29401 ttgtcaggga tgcgcaaaaa ataaatccca ggctggctgc acatgtgctc ctgtataaat
    29461 gccagccaaa tacgttcagt gaacaacaag aattaagaga ctctctcaac agccatgatt
    29521 actggcttaa accaatgaaa agcacggttt cttttctccg ggcctttgta agagcaatga
    29581 atcagggaat gggggttcac gagttaaaaa gtaatgttag cggtgccagc caggcaaaag
    29641 cacaaatcga actcttgctg aaagaactgg aactgtaaat catagtgaca tacactaatg
    29701 tacatcatca tgatatacat tagtgtgaaa caatcagatt agaaggtaca tcatggcaaa
    29761 gctggaacta ccagaactag aacaaaacca ggaagtgaac gccacaaaat ttgttcagga
    29821 cgcaggaaaa cgccccacag agaacaaaac aaaactggct tcattccgca taccgaatga
    29881 attgcttgaa ttcattgata acgaatcaaa aagactgcat cgtcccaaga caaaaataat
    29941 caaagcagca ttactggctt atcaggatct ggacgaaaac gaactcatta atttgtggtt
    30001 cagagctgac agaaatgatt aatcatagca agtggcccaa taaactcttt atcattttct
    30061 tttagatact tatctgaatg tactaacttc atcactttta aatgtagttg tgattcattt
    30121 ttagttactc ttgcaataaa atacccttgt acagttgttg cacgggtatt taggagcact
    30181 agatgagcct tatcgattta agtttatcag gattatcaga accaggaaca aaacttattg
    30241 aaaaaataag tgatgctatt ggtgtgcttt atgaacctac aagaatcagg aaaaaagcga
    30301 aggctgaagc tgaagctaaa cgcacagagc taatttctag gttagagctt gagggaatag
    30361 aaaaacgggc agttgagcgt tttctcaaac gtgaaacgaa acgacaggaa aacattgaaa
    30421 atataacaat gcaagcagca caaagtctat ctgagagtga taatgtttct gatattgacg
    30481 aagattggat agaggctttc ttcagggagt gtgaggatat tagtgacgaa caaatgcaaa
    30541 tgctttgggg aagaatttta tccgaagaag caaagtcaaa aggttcgttt agtcgtagaa
    30601 ccttaaaact attatccact ataagcaaag aagaagcgaa ccttattact tattttggaa
    30661 agtttgtttg gcaggcaaac aaactcactc caattttatt taccgatgag aatggagata
    30721 ctgaaggtat aactttcgat aaactttcgg ttttagactc cttaggcgtt attcaacaag
    30781 gcattggtta tagtttacaa attataaata ctctcaagtg tatattcagt atgggattgc
    30841 gcaatgattg cctaataaaa tttctgaaat atttctgtat cgcataattt tttatatcag
    30901 ataaattgta ctggatttct taaggaaggt gcgaataagc aggtcatttc ttcccaagct
    30961 gactcgttga ttaaaatttc gcggatctgg gccgattttt ttcccgcaaa cacatcgaat
    31021 cagcctattt aggctatttt ttccaccatt tctggcgtta tttccggttt ttactgagat
    31081 ctctcccact gacgtatcat ttggtccacc cgaaacaggt tggccagggt gaataacatc
    31141 gccagttggt tatcgttttt cagcagcccc ttgtatctgg ctttcacgaa gccgaactgc
    31201 cgcttgatga tgcgaaacgg gtgctccacc ttggcacgga tgctggcttt catgtattcg
    31261 atgttgatgg ccgttatgtt cttgcgcgga tgctgcttca aggtttttac cttgccggga
    31321 cgctcggcga tcagccagtc catatccacc tcggccagct cctcgcgctg tggcgctcct
    31381 tggtagccgg catcggctga gacaaattgc tcctctcaat taagcagatt acccagctga
    31441 ttgaggtcat gctcgttggc cgcggtggtg actaggctgt gggtcaggcc actcttggca
    31501 tcgacaccaa tatgggcctt catgccaaag tgccactgat tgcctttctt ggtctgatgc
    31561 atctccggat cgcgttgctg ctctttgttc ttggtagagc tgggtgcctc aatgatggtg
    31621 gcatccacca aagtgccttg ggtcatcatg acgcctgctt cggccagcca gcgattgatg
    31681 gtcttgaaca attgacgggc cagttgatgc tgctcgagca ggtggcggaa attaatgatg
    31741 gtggtgcgat ccggcagggc gctatccagg gataatcggg caaacaggcg catggaggcg
    31801 atttcgtaca gggcatcttc catggcaccg tcgctcaggt tgtaccaatg ctgcatgcag
    31861 tgaatacgca gcatggtctc cagcggatag ggccgtcggc cattgcccgc cttgggataa
    31921 aacggctcga tgacagcggt catattctgc catggcagaa tctgctccat gcgggagagg
    31981 aaaatctctt ttcgggtctg acggcgctta gtgctgaatt cactatcggc gaaggtgagt
    32041 tgatggctca tgatgtccct ctgggatgcg ctccggatga atatgatgat ctcatatcag
    32101 gaacttgttc gcaccttcct taaaaaattg cagtataatt gccgcaatta tcccaccgtt
    32161 tattttttga gtagtttctc atgatgcagc atacttctgt gtggtaccga cgctcggtca
    32221 gtccgtttgt tcttgtggcg agtgttgccg ttttcttgac cgcgaccgcc aatcttacct
    32281 tttttgataa aatcagccaa acctatccca tcgcggacaa tctcggcttt gtgctgacga
    32341 tcgctgtcgt gctctttggc gcgatgctac tgatcaccac gctgttatca tcgtatcgct
    32401 atgtgctaaa gcctgtgttg attttgctat taatcatggg cgcggtgacc agttatttta
    32461 ctgacactta tggcacggtc tatgatacga ccatgctcca aaatgcccta cagaccgacc
    32521 aagccgagac caaggatcta ttaaacgcag cgtttatcat gcgtatcatt ggtttgggtg
    32581 tgctaccaag tttgcttgtg gcttttgtta aggtggatta tccgacttgg ggcaagggtt
    32641 tgatgcgccg attgggcttg atcgtggcaa gtcttgcgct gattttactg cctgtggtgg
    32701 cgttcagcag tcattatgcc agtttctttc gcgtgcataa gccgctgcgt agctatgtca
    32761 atccgatcat gccaatctac tcggtgggta agcttgccag tattgagtat aaaaaagcca
    32821 gtgcgccaaa agataccatt tatcacgcca aagacgcggt acaagcaacc aagcctgata
    32881 tgcgtaagcc acgcctagtg gtgttcgtcg tcggtgagac ggcacgcgcc gatcatgtca
    32941 gcttcaatgg ctatgagcgc gatactttcc cacagcttgc caagatcgat ggcgtgacca
    33001 attttagcaa tgtcacatcg tgcggcacat cgacggcgta ttctgtgccg tgtatgttca
    33061 gctatctggg cgcggatgag tatgatgtcg ataccgccaa ataccaagaa aatgtgctgg
    33121 atacgctgga tcgcttgggc gtaagtatct tgtggcgtga taataattcg gactcaaaag
    33181 gcgtgatgga taagctgcca aaagcgcaat ttgccgatta taaatccgcg accaacaacg
    33241 ccatctgcaa caccaatcct tataacgaat gccgcgatgt cggtatgctc gttggcttag
    33301 atgactttgt cgctgccaat aacggcaaag atatgctgat catgctgcac caaatgggca
    33361 atcacgggcc tgcgtatttt aagcgatatg atgaaaagtt tgccaaattc acgccagtgt
    33421 gtgaaggtaa tgagcttgcc aagtgcgaac atcagtcctt gatcaatgct tatgacaatg
    33481 ccttgcttgc caccgatgat ttcatcgctc aaagtatcca gtggctgcag acgcacagca
    33541 atgcctatga tgtctcaatg ctgtatgtca gcgatcatgg cgaaagtctg ggtgagaacg
    33601 gtgtctatct acatggtatg ccaaatgcct ttgcaccaaa agaacagcgc agtgtgcctg
    33661 catttttctg gacggataag caaactggca tcacgccaat ggcaaccgat accgtcctga
    33721 cccatgacgc gatcacgccg acattattaa agctgtttga tgtcaccgcg gacaaagtca
    33781 aagaccgcac cgcattcatc cgctgatttc tccctgtatt ttttccaaac ccaccgcaca
    33841 ctccattcgt attatgggcg gtggggtggg gtttgttatg ccgtatttat caaataaacg
    33901 cctacttgct gagatgagta tcgctcttgt catggcgatc gttgccacgc tgacccttga
    33961 gcacagtcag attgatctga tggtcgctga ttggttttat ctgggtatgg ggcattggat
    34021 ggttgccaag caagcttttt tgccagattt gctactgtat tctggactaa aaaagctgct
    34081 gatggcgatg ctgatctact tgctggttgc gaccatttgc cgtgcttatc atgagaaaaa
    34141 gggcaatgct atcactgcca agtggcttgt cccagtgaca aaatttcgcg tgcgtgagct
    34201 tgcgtatctg gtgctgactt tgatcctagt gccgacagtt gtcgcgtcat tgaaggcata
    34261 tactcatgtg gtctgccctg tgcatttgac gatttttgat ggtacgctgc cgtatttgcc
    34321 gatgcttgat agtatgcgta acaccattcc tgataagtgc tttcctgcgg cgcatgccag
    34381 tagcggattt gcgctgtttg cctttgcgtt tgcgccaagt ttgcgccgcc gtcgtggtgc
    34441 gatcatcatc gtggtgatgg cattgggctg ggcgatgggc tgctataaga tgattattgg
    34501 cgat
//
