LOCUS       NZ_CP133851            30566 bp    DNA     circular CON 26-JAN-2024
DEFINITION  Citrobacter freundii strain CF2 plasmid unnamed1, complete sequence.
ACCESSION   NZ_CP133851
VERSION     NZ_CP133851.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN37200065
            Assembly: GCF_031432815.1
KEYWORDS    RefSeq.
SOURCE      Citrobacter freundii
  ORGANISM  Citrobacter freundii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 30566)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Plasmid analysis using q20 nanopore sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30566)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2023) HCAI, Fungal, AMR, AMU & Sepsis Division,
            United Kingdom Health Security Agency, 61 Colindale Avenue, London,
            London NW9 5EQ, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2023
            Assembly Method :: Flye v. 2.9.1-b1780; Medaka v. 1.7.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 33x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 11:57:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,426
            CDSs (total)                      :: 5,298
            Genes (coding)                    :: 5,130
            CDSs (with protein)               :: 5,130
            Genes (RNA)                       :: 128
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 16
            Pseudo Genes (total)              :: 168
            CDSs (without protein)            :: 168
            Pseudo Genes (ambiguous residues) :: 0 of 168
            Pseudo Genes (frameshifted)       :: 88 of 168
            Pseudo Genes (incomplete)         :: 77 of 168
            Pseudo Genes (internal stop)      :: 24 of 168
            Pseudo Genes (multiple problems)  :: 18 of 168
            Pseudo Genes (short protein)      :: 1 of 168
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP133851.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..30566
                     /organism="Citrobacter freundii"
                     /mol_type="genomic DNA"
                     /strain="CF2"
                     /isolation_source="drain"
                     /host="Homo sapiens"
                     /db_xref="taxon:546"
                     /plasmid="unnamed1"
                     /geo_loc_name="United Kingdom: England"
                     /collection_date="2022-10"
                     /genotype="ST162"
     gene            join(30183..30566,1..495)
                     /locus_tag="RHA96_RS02200"
                     /old_locus_tag="RHA96_02200"
     CDS             join(30183..30566,1..495)
                     /locus_tag="RHA96_RS02200"
                     /old_locus_tag="RHA96_02200"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="WP_044257108.1"
                     /translation="MTSLTLIPVTVGYLAIDRLNDAGNQQINVHSCFTNTMNLLLSDGE
                     LLILASEHTGLNHPDTIIVSVPANWDWRCTGRAGITFGDGIFSNPVWQMDIRHVKRWQQ
                     TDLYPLIMTETERKYTFLAEQLKVYSQRYPIKSAIMLLPDNMAKQVNRPLREVNIAIED
                     NEQQISQLVDGLIGFGFGLTPDGDDYLLGYLAAISFLPQDIISRHRRALTRIIISRLDR
                     TNDISQHYLKRATEGHFSEAICQLLTHLSAPFSPSPLAAAATAVMRFGASSGVDCLAGL
                     LHGIRASTRIH"
                     /name="DUF2877 domain-containing protein"
     gene            591..2141
                     /gene="fdrA"
                     /locus_tag="RHA96_RS02205"
                     /old_locus_tag="RHA96_02205"
     CDS             591..2141
                     /gene="fdrA"
                     /locus_tag="RHA96_RS02205"
                     /old_locus_tag="RHA96_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006229930.1"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="WP_049592200.1"
                     /translation="MKVLHGIFKNLYQDSVSLMQVSASIINLPGIKQASVVMGSETNLI
                     QLRDAGLGDNIAAGPNDLIIAIMGEDEACEQALALAKEKLNSKPQADTEAGRRLVQFTS
                     LAMAAEQDPEANLALISVPGDYAAAEAIKAIELGMHVMLFSDNVSLAEEKAIKTLARQK
                     NRLVMGPDCGTAIVNGIPLGFANVVRRGGIGIVGASGTGLQEVTCRIDQLGGGISQALG
                     TGGHDLHEEIGGISMLMGLNALAEDDETQVIVLISKPPAYDVAERVLTQAQKAGKPVVV
                     NFLGAAPQSVTRPGVVAALTLAEAAELAMSFVAPESAQQAQSSACCTEDEFIQKQTQIN
                     GADNSRRYIRGVFAGGTFCYESQLICQRNGITAHSNTPIKGNLALNNIWQSEGHTLIDM
                     GDDDFTRGRPHPMIDPTLRNQRIIAEINDPQTAVVLFDLVLGYGAAPEPAEELLKLLNA
                     TNRAASPLLIAHVCGTQSDPQQRSVQIGALRRYGVLVADSNAQATCWAASAVNNLGNK"
                     /name="fdrA"
     gene            2151..3572
                     /locus_tag="RHA96_RS02210"
                     /old_locus_tag="RHA96_02210"
     CDS             2151..3572
                     /locus_tag="RHA96_RS02210"
                     /old_locus_tag="RHA96_02210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="WP_049592199.1"
                     /translation="MNSLFSQSLNVINEGLASFADNIRQAGGKVTPLNWQPPAEGDRFT
                     GLSLAGLINHPVVERANQVAMGRYLDAQPVLVDVLTAAVAIPAMAEQKLILHAGPPIAW
                     EEMCGPVKGAIIGAILFEGWAASKDVASRLVLNGEIALAPCHHYDAVGPMAGVISPSMP
                     LWVIENKTNGKRAFSNFNEGLGKVLRFGANNEEVLERLTWISQELGPVMKAAVCQLGEL
                     ELKPIMAQALHMGDEVHNRNAAATGLLIKRLFPVLLRCNLPNVQLQKVVSFISGNDHFF
                     LNLSMAASKSMMDAAANVPFSSLVTVMARNGVNFGIRLSGLGDQWFQAPANPVEGLFFP
                     GYSVEDAAADLGDSAITETAGVGGFAMASSPAIVKFVGGTPADATENSRRMQFITVGSN
                     PAFTLPALNFSPTAAGIDARKVVDRSILPIINTGIAHKEAGVGQIGAGITTAPMACFSA
                     AIRALAQKLTEENPE"
                     /name="DUF1116 domain-containing protein"
     gene            3569..4531
                     /gene="arcC"
                     /locus_tag="RHA96_RS02215"
                     /old_locus_tag="RHA96_02215"
     CDS             3569..4531
                     /gene="arcC"
                     /locus_tag="RHA96_RS02215"
                     /old_locus_tag="RHA96_02215"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606533.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0008804 - carbamate kinase activity [Evidence IEA]"
                     /GO_process="GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]; GO:0016310 - phosphorylation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="WP_001549941.1"
                     /translation="MSKPLAVVAVGGNALIADDKRNSIDEQYACVTDSVRYLCDMIEVG
                     WEMLLTHGNGPQVGFILRRSEISREEVSPVPLDYAVGDTQGAIGYMFQKAFKNELQRRG
                     IHKPIVSLVTQTLVDKDDAAFSHPSKPIGAFLDRHTAMQRQKELGWTIMEDSGRGWRRT
                     VPSPQPLEIIELETIAQLLRYGCIVIACGGGGIPVVRDRDGMLHGVEAVVDKDLASALI
                     ADKLHAELLLISTGVEQVAVNFGTPEQRGINSLTIAEAQQLLKEGQFGEGSMQPKVEAI
                     VDFVSRSQSKGRSAKGLITSPNAIHAALQHKTGTWIGEE"
                     /name="arcC"
     gene            4779..5681
                     /locus_tag="RHA96_RS02220"
                     /old_locus_tag="RHA96_02220"
     CDS             4779..5681
                     /locus_tag="RHA96_RS02220"
                     /old_locus_tag="RHA96_02220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_049592198.1"
                     /translation="MFISDEVLRIVHLVAHYQSIATAAEQLNKVPSALSYTIKKLEESL
                     GVELFERKGRNIGLTPSGEYFIQHSKPILNDIDSLCRNTTLIHTGVEQELTVAFNNIVP
                     KNIISEFISEFEKTFDFTQLTVNTEVYNGCWDAIYHNRADVVVGAPHSVPSSDGIISEH
                     VGYMDWDFVVGPQHSLATHIHPLENRELRQYTAVCIRDTATNFIPLYAWHLEGQKAVFV
                     PDLEIAISLIKSNTAIGYLPHHLARPLLNNGRLIKKSMLEHKHATQLFVAAKTDGLGEA
                     GRWCLEYWLRPDIKFRLNG"
                     /name="LysR substrate-binding domain-containing protein"
     gene            complement(6466..7170)
                     /locus_tag="RHA96_RS02225"
                     /old_locus_tag="RHA96_02225"
     CDS             complement(6466..7170)
                     /locus_tag="RHA96_RS02225"
                     /old_locus_tag="RHA96_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(7207..7965)
                     /locus_tag="RHA96_RS02230"
                     /old_locus_tag="RHA96_02230"
     CDS             complement(7207..7965)
                     /locus_tag="RHA96_RS02230"
                     /old_locus_tag="RHA96_02230"
                     /inference="COORDINATES: protein motif:HMM:NF021897.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="WP_326971576.1"
                     /translation="MDDRERGLAFLFAITLPPVMVWFLVAKFTYGIDPSTAKYLIPYLV
                     KNTFSLWPLWSALIAGWFIGVGGLIAFIIYDKSRVFKGERFKKIYRGTELVRARTLADK
                     TRERGVNQLTVANIPIPTYAENLHFSIAGTTGTGKTTIFNELLFKSIIRGGKNIALDPN
                     GGFLKNFYRPGDVILNAYDKRTEGWVFFNEIRRSYDYERLVNSIVQESPDMATEEWFGY
                     GRLIFSEVSKKLHSLYSTVTMEGTVANSRW"
                     /name="type IV secretion system DNA-binding
                     domain-containing protein"
     gene            complement(7967..8257)
                     /locus_tag="RHA96_RS02235"
                     /old_locus_tag="RHA96_02235"
     CDS             complement(7967..8257)
                     /locus_tag="RHA96_RS02235"
                     /old_locus_tag="RHA96_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001471781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000706094.1"
                     /translation="MKIVADRLSDVNRKLDYLFDRASDADFGPLRDELKAITETLSGVK
                     FPPAGQMMLHESLAIETLILLRSIAEPGKTKAAKAEVERNGYKVWEPKKER"
                     /name="hypothetical protein"
     gene            8951..9337
                     /gene="stbA"
                     /locus_tag="RHA96_RS02240"
                     /old_locus_tag="RHA96_02240"
     CDS             8951..9337
                     /gene="stbA"
                     /locus_tag="RHA96_RS02240"
                     /old_locus_tag="RHA96_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_013279398.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRQNRKNVLHNTHDKSSAKGAAESVLHNTQPSEPEAQESEKAESP
                     GIIDKEFFNKIGEDFNPKKFNKKF"
                     /name="stbA"
     gene            9346..10062
                     /gene="stbB"
                     /locus_tag="RHA96_RS02245"
                     /old_locus_tag="RHA96_02245"
     CDS             9346..10062
                     /gene="stbB"
                     /locus_tag="RHA96_RS02245"
                     /old_locus_tag="RHA96_02245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StbB family protein"
                     /protein_id="WP_012561139.1"
                     /translation="MKVAVINYSGSVGKTLISSYLLAPRLTGAKFYAVETINQSASDLG
                     IENVTSFKGDDFSRLIEDIVFEDAGIIDIGASNVEAFLMAMSRFDSGANEFDKYVIPVT
                     PDNKAIDESLKTAHTLSKAGVSSKKIIFVPNRISPDSEVEDVLAPVFEFVKETKIGKIS
                     KKAVIYNSEVFEYLAFHRISFEVLTAEDPEEFKSRAKQTTDADERKKLARRYTYMKQAI
                     PVKANLDKAYAALMGE"
                     /name="stbB"
     gene            10064..10432
                     /gene="stbC"
                     /locus_tag="RHA96_RS02250"
                     /old_locus_tag="RHA96_02250"
     CDS             10064..10432
                     /gene="stbC"
                     /locus_tag="RHA96_RS02250"
                     /old_locus_tag="RHA96_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbC"
                     /protein_id="WP_012561138.1"
                     /translation="MEKQPDKLEVLMDWFLGDAKEITATQKEMTQKLSELSEKLAKDTE
                     SLGETADSFKRALVENQRSISLAISDDAKAREEFLTKFRRAQASSAETFTRQILFITAG
                     CTIVGAAVGAAIAILLLR"
                     /name="stbC"
     gene            10633..10977
                     /locus_tag="RHA96_RS02255"
                     /old_locus_tag="RHA96_02255"
     CDS             10633..10977
                     /locus_tag="RHA96_RS02255"
                     /old_locus_tag="RHA96_02255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_326971577.1"
                     /translation="MNDRQRELARIRQARRRARLKEECTSVTVTLTKQEEAMLQELCRV
                     RRPGRTPYSTNEFFQLLLIRNWQQWQEQKSQLGKCQACGKLKAEGGCEGERKGETFNCW
                     LAVEANELNL"
                     /name="hypothetical protein"
     gene            complement(11439..11618)
                     /gene="ccgAI"
                     /locus_tag="RHA96_RS02260"
                     /old_locus_tag="RHA96_02260"
     CDS             complement(11439..11618)
                     /gene="ccgAI"
                     /locus_tag="RHA96_RS02260"
                     /old_locus_tag="RHA96_02260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CcgAI"
                     /protein_id="WP_012561134.1"
                     /translation="MTTVTTPSQLKKEVESQKELLLRACLEAFNQLPNQRLQGAFQSTY
                     ALAAKLSQLLQQTK"
                     /name="ccgAI"
     gene            complement(12503..12742)
                     /locus_tag="RHA96_RS02265"
                     /old_locus_tag="RHA96_02265"
     CDS             complement(12503..12742)
                     /locus_tag="RHA96_RS02265"
                     /old_locus_tag="RHA96_02265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_016359300.1"
                     /translation="MLNKTENNTNISSINPCSTEGLIAVTGNDGETHIIQRELISHSVK
                     GHEATIIHLVTGKWIRVSLSSEILAKKLGITASE"
                     /name="hypothetical protein"
     gene            complement(12752..13156)
                     /gene="ardR"
                     /locus_tag="RHA96_RS02270"
                     /old_locus_tag="RHA96_02270"
     CDS             complement(12752..13156)
                     /gene="ardR"
                     /locus_tag="RHA96_RS02270"
                     /old_locus_tag="RHA96_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdR"
                     /protein_id="WP_000881513.1"
                     /translation="MLATLQHPTAWQLPDRLMLLELLMFDYRNSDQERYGQQIYHHYRK
                     QGNHRWDTSVHQDSGGQYAIIFRHSFSKKQADGVKRTMIRDETVIRAGTAQELTEATFP
                     DFQDSDILKASDFFKSLIQRKAADVTQTDI"
                     /name="ardR"
     gene            complement(13214..13639)
                     /gene="ardB"
                     /locus_tag="RHA96_RS02275"
                     /old_locus_tag="RHA96_02275"
     CDS             complement(13214..13639)
                     /gene="ardB"
                     /locus_tag="RHA96_RS02275"
                     /old_locus_tag="RHA96_02275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdB"
                     /protein_id="WP_000447669.1"
                     /translation="METIEITARYISENARMNFMPAAFRGAFFSADHFIQSFLNRYAKD
                     YQGGYWEYLQASNGAFFMEAPQPLWLSLPNYFEGECSAREVGIIVCLYAYSYFCGLAYE
                     EGKAELNETMANRYHLLREYVNTLENESQNRIYRAID"
                     /name="ardB"
     gene            14055..14495
                     /gene="mucA"
                     /locus_tag="RHA96_RS02280"
                     /old_locus_tag="RHA96_02280"
     CDS             14055..14495
                     /gene="mucA"
                     /locus_tag="RHA96_RS02280"
                     /old_locus_tag="RHA96_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_107685442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit MucA"
                     /protein_id="WP_000861760.1"
                     /translation="MKVDIFESSGASRVHSIPFYLQRISAGFPSPAQGYEKQELNLHEY
                     CVRHPSATYFLRVSGSSMEDGRIHDGDVLVVDRSLTASHGSIVVACIHNEFTVKRLLLR
                     PRPCLMPMNKDFPVYYIDPDNESVEIWGVVTHSLIEHPVCLR"
                     /name="mucA"
     gene            14483..15748
                     /gene="mucB"
                     /locus_tag="RHA96_RS02285"
                     /old_locus_tag="RHA96_02285"
     CDS             14483..15748
                     /gene="mucB"
                     /locus_tag="RHA96_RS02285"
                     /old_locus_tag="RHA96_02285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     MucB"
                     /protein_id="WP_016359299.1"
                     /translation="MFALIDVNGMYASCEQAFRPDLANRAVAVLSNNDGNIVARNYLAK
                     KAGLKMGDPYFKVRPIIERHNIAIFSSNYTLYASMSARFAAVVESLASHVEQYSIDELF
                     VDCKGITAAMSLDAFGRQLREEVRRHTTLVCGVGIARTKTLAKLCNHAAKTWPATGGVV
                     ALDDGARLKKLMSILPVAEVWGVGHRTEKALATMGIKTVLDLARADTRLIRKTFGVVLE
                     RTVRELRGEACFSLEENPPAKQQIVVSRSFGQRVETLTDMQQAVTGFAARAAEKLRNER
                     QYCRVISVFIRTSPYSVRDTQYANQATEKLTVATQDSRTIIQAAQAALARIWREDIAYA
                     KAGVMLADFSGKEAQLDLFDSATPSAGSEALMAVLDGINRRGKSQLFFAGQGIDNSFAM
                     RRQMLSPDYTTDWRSIPIATIK"
                     /name="mucB"
     gene            15899..16690
                     /locus_tag="RHA96_RS02290"
                     /old_locus_tag="RHA96_02290"
     CDS             15899..16690
                     /locus_tag="RHA96_RS02290"
                     /old_locus_tag="RHA96_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_053390190.1"
                     /translation="MNLPTPETYDELQRAYDFFNEKLFSNELPPCLITLQREKRTYGYC
                     SFKRFVGRESGYTVDEIAMNPVYFSIRTIKATLSTLVHEMVHQWQFHFGEPGRRGYHNK
                     QWAARMERVGLMASDTGEPGGRKVGQSMTHYIIAGGPFDMACDELLTGHFRLSWMDRFP
                     PYQPKPGAVLSPTGKGYIDDEEDDSEHEQEVEEGRDPVELDDEIIEAMRFVTPPPEAPV
                     NKTNREKYSCPVCHINLWGKPGIVVYCGGEHCNKAALVVLK"
                     /name="SprT-like domain-containing protein"
     gene            complement(16705..17046)
                     /gene="ardK"
                     /locus_tag="RHA96_RS02295"
                     /old_locus_tag="RHA96_02295"
     CDS             complement(16705..17046)
                     /gene="ardK"
                     /locus_tag="RHA96_RS02295"
                     /old_locus_tag="RHA96_02295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdAB regulator ArdK"
                     /protein_id="WP_000057569.1"
                     /translation="MAQKNRISETEWKQLLPQMASFAHITTDIGYSVLVKGEKSSDVAT
                     RVGRSKQNISSTVKRIWDLYQNTTLKAENGEPLKLVQVWIPASLAETVLKEAAKYSINN
                     ITTSEMEKK"
                     /name="ardK"
     gene            17606..18325
                     /locus_tag="RHA96_RS02300"
                     /old_locus_tag="RHA96_02300"
     CDS             17606..18325
                     /locus_tag="RHA96_RS02300"
                     /old_locus_tag="RHA96_02300"
                     /function="initiation of plasmid replication"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561120.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_013263795.1"
                     /translation="MDKLLNKKIKVKQSNELTEAAYYLSLKAKRVLWLCLMQTYFTASV
                     SEDDDEMAVLGDSTFKVKVADYQQIFQVSRNQAIKDVKEGVFELSRSAVIFYPKEGRFD
                     CVARPWLTEAGSRSARGIWEIEFNHKLLRYIYGLTNQFTTYSLRDCGSLRNPRTIRLYE
                     SLAQFKSSGLWVTTHAWLNDRFLLPESQQKNLAELKRSFLDPALKQINEKTPLLAKYSI
                     DDSGKFLFSIIDKQNPV"
                     /name="replication initiation protein"
     gene            20804..22279
                     /locus_tag="RHA96_RS02305"
                     /old_locus_tag="RHA96_02305"
     CDS             20804..22279
                     /locus_tag="RHA96_RS02305"
                     /old_locus_tag="RHA96_02305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020324153.1"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="WP_020324153.1"
                     /translation="MLRKIIRGSGFTQSEEKLIEFADDAFFGLWSYPNVYSDEGYSKNK
                     IGKEVSDLLVIFDKDIIIFSDKAITYNKNKDPKVAWQRWFKKSVIQSCTQLFGAEKFIK
                     DHPERLFVDKECSVNLPIKIDNSFNFHLVAVTNNISDPAISYFDKIEKGSSATLVNIFP
                     LNAHQCLENPFCVGDVYPDKTFVHILDETALKLLLTELNTATDFIGYLNEKERVVRERT
                     LLVSAGEEETLAAYIMGDKTIISKEIIGNDQGMTIPEGEWKNYKTTFNYQYQLSMKKGS
                     VFWDNLIHNFSTSILSANVGFFSEIEFSTHELGVRELAKESRQSRYYLSKNFKEKLKTT
                     QPHLRTSRMVESIDEPGKFYLFLFFPNDSKLSYSDYRIQRISYINAYAEVAFNKYRHIK
                     KLITIATEPQNTEGRSEDLIYSISPEKFTKEQNEKAKRLSREYKILSDFLPTKTTKSDN
                     FKSVISKGEKIGRNTPCPCGSGVKFKKCHGANN"
                     /name="SEC-C metal-binding domain-containing protein"
     gene            22900..23604
                     /locus_tag="RHA96_RS02310"
                     /old_locus_tag="RHA96_02310"
     CDS             22900..23604
                     /locus_tag="RHA96_RS02310"
                     /old_locus_tag="RHA96_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<23661..25124)
                     /locus_tag="RHA96_RS02315"
                     /old_locus_tag="RHA96_02315"
                     /pseudo=""
     CDS             complement(<23661..25124)
                     /locus_tag="RHA96_RS02315"
                     /old_locus_tag="RHA96_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612398.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            25219..25824
                     /locus_tag="RHA96_RS02320"
                     /old_locus_tag="RHA96_02320"
     CDS             25219..25824
                     /locus_tag="RHA96_RS02320"
                     /old_locus_tag="RHA96_02320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509966.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGRAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            26168..27403
                     /locus_tag="RHA96_RS02325"
                     /old_locus_tag="RHA96_02325"
     CDS             26168..27403
                     /locus_tag="RHA96_RS02325"
                     /old_locus_tag="RHA96_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011393614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001549948.1"
                     /translation="MEIVVLLPLLVMLILVLRNKHMILAGLVGGLTAMLVGGIGFSQAS
                     KIVMTSIPGMTGIITPVIYSAVALVLAKLGGFEALLGLSRRVFGRKQYLIAAAIVLTQA
                     LATYAAGLGAGNTMVTGPLALAIVGAVPQLIAGMAIVTAASFMTSPSGADAAAISKIAN
                     IEIATYSDTMFPITVCLWTLGMTIAAFGVWKSGSVLQDEDTMSDVTLKEQLIKVMPPVY
                     FLVVVVAGKNLNELFDYSLFSPIFNMFSTLMLGFAVTRQSPGKLAEELVQNSSFLLTKL
                     FAIGIFLGFINILAEIGTFTYIAEFIKSSPAFVTVPVAVFIAFCISIPAGGYSVGVSTL
                     VMPIMVESGLSITQIGLAALAVGVGTQMSPVQINVASLSQSFKLDIQRIVKINAPYMAG
                     VAAILCIMGFFL"
                     /name="hypothetical protein"
     gene            27456..28559
                     /locus_tag="RHA96_RS02330"
                     /old_locus_tag="RHA96_02330"
     CDS             27456..28559
                     /locus_tag="RHA96_RS02330"
                     /old_locus_tag="RHA96_02330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011393610.1"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-opening amidohydrolase"
                     /protein_id="WP_001549947.1"
                     /translation="MQKVEVFRIPTASPDDVSGLKNLIENGSVDPRDIIAVLGKTEGNG
                     CVNDFTRGFATQSLSIFMAEQLDMSVSAVQERIAFVMSGGTEGVMSPHLTVFTRKEVDQ
                     PAKEGKRLAAGIAFTRDFLPEEIGRMAQVKEVAEGVRIAMKDAGITDPQDVHFVQIKCP
                     LLTADRIEDARVRGQTVAVHDTYKSMAYSRGASALGVALALGEVSEDALNDKVICQDWT
                     LYSGVASTSAGVELLKDEIIVIGNAENTTSDLRIGHAVMQDAIDIDALFAAMREAGLEF
                     DGLPPQEELDRIVNVLAKAEASSTGTVRGRRNTMQDDSDINHTRSARAVVNAAIAAITR
                     DPLVYVSGGAEHQGPDGGGPISVIAKV"
                     /name="ring-opening amidohydrolase"
     gene            28681..29985
                     /locus_tag="RHA96_RS02335"
                     /old_locus_tag="RHA96_02335"
     CDS             28681..29985
                     /locus_tag="RHA96_RS02335"
                     /old_locus_tag="RHA96_02335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549946.1"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_275396578.1"
                     /translation="MNNHFVGIDEKPPFLSLLLMGIQHVLVLFSGLVAVPLVVGMALGL
                     PSTDITVLVQGSLIVSGTGTLIQCLGLGHLGSRLPICMGSAFVFIAPSITVGSQMGIQA
                     VFGASMVCGFVAWILSFFIGRVQKLIPPLVTGTIVSLIGIKLLPLGFTWLAGGHSELYG
                     KPVCFLIGGVVLVALLVASQSRKGLLSSFSVIIAIMLGYVVSALLGILDLHHVQDASWV
                     SFPDLLHFGWPTFSYSAIVIMMIAQLTAVLESIGNTYGTGAAVRREITHKHLSGAISVD
                     GIGSIVAPLLNGFPLTCFAQNIGVISITRVASRYVVASAGVVLIALGLIPKFSALVAGM
                     PAPVLGGASLIMFGSIVGSGVAQIKDSGPFDQRAAMVFSTSLALGLGFGLAPKDAFDAF
                     SPSLVVLLESGVAIGGMAAIILNLVLPRSPEPSVS"
                     /name="nucleobase:cation symporter-2 family protein"
     Typing          complement(8446..8703)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.077"
                     /coverage="100.0"
                     /evalue="1.7700000000000002e-124"
     Typing          17607..18325
                     /name="IncN"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.444"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacagtcaga gatatccgat caaaagtgca attatgctgt tgcccgataa tatggctaaa
       61 caggtaaatc gaccattgcg cgaagtaaat atcgccattg aagataatga gcagcagatt
      121 agccagctgg ttgacggatt aattggtttt ggtttcggtc tgacacccga tggcgacgat
      181 tatcttctcg gatatctcgc agccatctct tttttgccac aggacattat ttcgaggcat
      241 cgacgggcgc ttaccagaat tattatatcg aggctggatc gtaccaatga tattagccag
      301 cattatctga agcgcgcgac ggagggccat ttttctgaag cgatttgtca gctgctgacg
      361 cacctatcgg cgcctttttc accttcgcct cttgcggcgg cggcgacagc tgtcatgcgg
      421 tttggcgcct cttccggagt cgattgtctg gctggactac ttcatggcat acgtgcgtca
      481 acccgcattc attaaggcat aacacgatgt gttttaccgg agggattttc cctcttacga
      541 ctaattgttg ctgatttctt atggcaatgg cgaatgaaca ggtagcctac atgaaagtac
      601 tacacggtat ttttaaaaat ctttatcagg attccgtttc cctaatgcag gtttccgcaa
      661 gcatcatcaa tttgcctggt attaagcagg catccgttgt gatgggaagt gagaccaatc
      721 ttattcaatt aagagacgca gggctgggcg acaatattgc tgcaggtcct aacgatctta
      781 ttattgcgat tatgggggaa gatgaggcct gcgagcaggc actggcactg gcgaaggaga
      841 aacttaacag taagccgcag gctgatacag aagccgggag aaggctggta cagtttacca
      901 gcttggctat ggcggctgaa caggatccag aggctaattt ggcgctgatc tccgttcccg
      961 gcgattatgc tgccgccgag gcaatcaaag ctattgagct cggtatgcat gtcatgctgt
     1021 ttagtgacaa tgtgagtctc gccgaggaaa aagcgatcaa aacccttgct cggcagaaaa
     1081 atcggttggt gatggggcct gattgcggta cggcgattgt taatgggatc ccgctggggt
     1141 ttgctaacgt tgtccgcaga gggggtattg gcattgttgg tgcttccggc acggggttgc
     1201 aggaagtcac ctgccgcatt gatcaattgg gcggagggat ttcccaggcg ttagggaccg
     1261 gtggccatga tttacacgag gaaattggtg gtatcagcat gctgatgggg ctgaatgccc
     1321 tggcggaaga tgatgagacg caggtgattg tccttatttc caaaccgcca gcctatgacg
     1381 ttgcggaaag ggttctcacc caagcgcaga aagcaggaaa acccgttgtt gtaaactttt
     1441 taggtgctgc accgcagagc gttacgcggc caggtgttgt tgccgcatta acgctggcag
     1501 aggccgctga actggctatg tcgtttgttg cgccagagtc cgctcagcag gcgcagtcat
     1561 cagcatgctg tactgaagat gaatttattc aaaagcaaac gcagattaac ggcgccgata
     1621 attcacgtag atatatacgg ggcgtttttg cgggcggaac attttgttat gaaagtcagt
     1681 taatttgcca gcgtaatggt ataaccgccc attctaatac gccaataaaa ggaaacttag
     1741 cgctaaataa tatctggcag agtgaggggc ataccttaat tgatatgggg gatgatgatt
     1801 tcacccgcgg ccgtccacac cccatgatcg acccgacgct gcgtaatcag cggattatcg
     1861 ctgaaattaa cgatccgcaa acggcggttg tgctttttga tcttgttctt ggctatggcg
     1921 cagcaccgga gccagccgaa gaattactga aactgctcaa tgctaccaac agagcggcca
     1981 gcccgttatt aatagcccat gtttgtggaa cacagagcga tccacaacag cgtagcgtgc
     2041 aaattggcgc cttgagacgc tatggcgttc tggttgctga cagcaacgct caggctacat
     2101 gctgggccgc cagcgcagta aataatctgg gaaataaata aggaactgat atgaactcat
     2161 tattttctca gtcacttaat gtgattaacg aaggccttgc cagttttgcc gataatatca
     2221 ggcaagccgg gggaaaggtc actcctttga actggcagcc gcccgctgaa ggggatcgtt
     2281 ttaccgggct gtccctcgcg gggcttatta accatcccgt cgtggagcgc gccaatcagg
     2341 tggcaatggg gcgctatctt gacgctcagc cggtattagt ggatgtcctg accgcggctg
     2401 tggcgattcc ggcaatggcg gaacaaaaat taattctgca tgccggtccc cctatcgctt
     2461 gggaagagat gtgcgggccg gtcaagggtg ccattatcgg cgcaatattg tttgaaggct
     2521 gggcggcaag taaagatgtg gcatctcgtt tggttcttaa tggcgaaatt gcccttgctc
     2581 cgtgccacca ttacgacgcc gttggcccta tggccggcgt tattagtcct tcgatgccgt
     2641 tgtgggtaat cgaaaataaa actaacggca agcgtgcctt cagtaacttt aatgaaggcc
     2701 tgggcaaagt tttacgcttt ggggcgaaca atgaagaggt cctggagcgc ttaacatgga
     2761 tatcgcagga attaggcccg gtaatgaaag cggcggtgtg ccagttgggt gagcttgaac
     2821 taaaacccat aatggctcag gcgttgcata tgggggatga ggtacataac cgtaatgccg
     2881 ccgcgacggg gctgctaatt aagcgtttat ttcccgtgct gctgagatgt aacttaccga
     2941 acgtccagct tcagaaggtc gtgtcattta tttctggtaa cgatcatttc ttcctgaatc
     3001 tttctatggc ggcaagtaag tcgatgatgg atgccgccgc taatgtacca ttcagctcgc
     3061 tagtgactgt tatggcacga aatggcgtca acttcggtat ccggctctcg ggccttggtg
     3121 accagtggtt ccaggcgccg gccaacccgg tagaagggtt atttttccct ggctatagcg
     3181 tagaggacgc cgcggctgat ctgggagata gcgccattac tgaaaccgca ggcgtgggcg
     3241 gctttgcgat ggcatcttcc ccggccatcg ttaaatttgt gggggggacc cccgctgatg
     3301 caactgaaaa tagccgacgc atgcagttta ttaccgtggg ctcaaaccct gcgtttactc
     3361 tacctgccct gaacttttca ccgaccgcgg ccggtatcga cgcgcgtaaa gttgtcgatc
     3421 gcagcatact accgattatc aacaccggta tcgcccataa ggaagccggc gttggccaga
     3481 ttggcgccgg aatcaccacg gctccgatgg cctgctttag tgcagcgatt cgggctcttg
     3541 cgcaaaagct cactgaggag aatcccgaat gagtaaacct ttagccgttg tggccgtggg
     3601 cggaaatgcg ctcattgccg atgacaagcg taatagtatt gatgaacagt atgcgtgtgt
     3661 cactgattcc gttcgctatc tttgcgatat gatcgaggtc ggttgggaaa tgttgttaac
     3721 tcatggcaac gggccacagg tcggcttcat tctgcgtcgt tctgaaatat cccgggagga
     3781 agtctctccg gtccccctcg actacgcggt gggtgatacg cagggagcga ttggttatat
     3841 gttccagaaa gcgttcaaaa atgagctgca gcggcgcggt attcacaaac ctatagtctc
     3901 actagtgacg caaacccttg tcgataaaga tgatgccgcg ttcagccacc cctcaaaacc
     3961 cattggcgcg tttctggatc gccataccgc tatgcagcgc cagaaagagc tgggctggac
     4021 aatcatggag gactcagggc gcggctggag acgtaccgtt ccatcacctc agccactgga
     4081 aattattgag cttgaaacca ttgctcagtt attgcgttac ggttgtattg tgattgcctg
     4141 tggcggtggc ggtattcccg ttgttcgcga tcgtgatgga atgttgcatg gtgtagaggc
     4201 ggttgttgat aaggatttag cctcagccct gatagcagat aaactccatg ccgaattact
     4261 gctgatatcc actggggttg aacaggttgc tgtcaacttt ggtacgcccg agcagcgggg
     4321 gatcaatagc ctgactatcg ctgaggctca acaattgctc aaagaagggc aatttggtga
     4381 aggaagtatg cagcccaagg tcgaagcgat tgttgatttt gtgtcgcgta gccagtcgaa
     4441 agggagaagt gcgaagggac ttattaccag tccgaatgcc attcacgcgg ctttgcagca
     4501 taaaaccggc acctggattg gagaggagta atccgctgcg gtaaccctta aatccgccgc
     4561 ggctgctatc catgctgatg acaatcgcgg cgttagcagg aggggggaga gtttgctcct
     4621 gcgacaaatc cttgcagcct ggcgtcacgc tatcgggtgc tggctttttc caaactaaat
     4681 cccttgtgtt atgtttatag gtgtcaccat catctatgat ttacaggcga cgatcagaat
     4741 cagaggtact gccgggatag caacacaggg agatagagat gttcatttct gatgaagtat
     4801 tgcgcatagt tcatctggtt gcacactatc agagcattgc aacggccgct gaacagctca
     4861 ataaagtacc ttcggcgtta agctatacaa taaaaaagct ggaagaaagc ctcggcgtgg
     4921 agttattcga gcgtaaggga cgaaacatcg ggctaactcc ttcaggggag tactttattc
     4981 aacacagtaa acccattctc aacgatattg attctttatg tcgtaatacc acattaatcc
     5041 atactggggt tgaacaagaa ttaacggtag catttaataa tattgtgcct aaaaatatta
     5101 tttcagaatt tatttcagaa tttgaaaaaa cattcgactt tacgcagtta acagtaaaca
     5161 ctgaagttta taacggctgc tgggacgcca tttatcacaa tcgtgcggat gtggttgttg
     5221 gcgcccctca ctccgtgcca tccagtgatg gaataataag cgaacatgtt ggctatatgg
     5281 attgggattt tgttgttggt ccgcaacatt cgctagctac tcacattcac ccattagaaa
     5341 acagagagtt acgccaatat actgctgttt gcatccggga tacggcgacg aattttatcc
     5401 ctctttatgc ctggcatctt gagggacaaa aagcagtatt tgtacccgat cttgaaatcg
     5461 ctatttcgct gataaaaagt aatactgcga taggatacct tccccatcat ttagccaggc
     5521 cgctactgaa caatggtaga ttaataaaga aatctatgct tgagcataag cacgcgacgc
     5581 agttatttgt ggccgcgaaa acggatggtt tgggagaggc aggccgctgg tgccttgaat
     5641 actggctgcg tccggatatt aaattcaggc tgaatggtta ggttcgaata aaaagtcttc
     5701 ctcattttta cccagtaaat ctgttgaaca aggtatgtta tgatcttgct ctgtatctgt
     5761 gaacgaaatc tatttttact ccctgataaa attaattgat aatattatta gagtgcaaat
     5821 attttctatg caattcttgt ggtttctaag gtattagact gttatcacgc aaaaattgct
     5881 acagttgtat atatgcattt gtttgggttg ttcagggcca acataagaag ctagcgataa
     5941 aatcataaaa atttagcata ttactaatat caaatcatga ggagccgagc tcattatggt
     6001 ttcattctca ttgtattttt gattgtagtt aatgcctatt aacgaaggtg gcgaaaatat
     6061 ttgcaatatt taaagattca tagggatttt tagtttggta atttttaatt gaaatatctt
     6121 atttatatta tcctgtagct gatgcgctag gacgatataa agtaatggtg ttcaccagag
     6181 aacaccattt gacaagtaga gcaatctatc atttatactg gttagttttt ttttgcttat
     6241 cagtatttct tgtgcttttg ctatttccct tattagtttg ctggttcctt tgttcctgtt
     6301 aagctgattt gcatgatgat cggcgttagc tttatcatat tgatatttat ttgtgtttga
     6361 catgttaaat ttcatttata ttcaatacgg atttttattg tacacttgaa tcaggcactg
     6421 ttgcaaagtt agcgatgagg cagccttttg tcttattcaa aggccttaca tttcaaaaac
     6481 tctgcttacc aggcgcattt cgcccagggg atcaccataa taaaatgctg aggcctggcc
     6541 tttgcgtaat gcacgcatca cctcaatacc tttgatggtg gcgtaagccg tcttcatgga
     6601 tttaaatccc agcgtggcgc cgattatccg tttcagtttg ccatgatcgc attcaatcac
     6661 gttgttccgg tacttaatct gtcggtgttc aacgtcagac gggcaccggc cttcgcgttt
     6721 gagcagagca agcgcgcgac cataggcggg cgctttatcc gtgttgatga atcgcgggat
     6781 ctgccacttc ttcacgttgt tgaggatttt acccagaaac cggtatgcag ctttgctgtt
     6841 acgacgggag gagagataaa aatcgacagt gcggccccgg ctgtcgacgg cccggtacag
     6901 atacgcccag cggccattga ccttcacgta ggtttcatcc atgtgccacg ggcaaagatc
     6961 ggaagggtta cgccagtacc agcgcagccg tttttccatt tcaggcgcat aacgctgaac
     7021 ccagcggtaa atcgtggagt gatcgacatt cactccgcgt tcagccagca tctcctgcag
     7081 ctcacggtaa ctgatgccgt atttgcagta ccagcgtacg gcccacagaa tgatgtcacg
     7141 ctgaaaatgc cggcctttga atgggttcat gtgcagctcc atcagcaaaa ggggatgata
     7201 agtttatcac caccgactat ttgcaacagt gccttccata gttactgtgc tgtataggct
     7261 gtgaagtttt ttcgaaactt cactaaaaat aagacggcca tagccgaacc attcttcagt
     7321 agccatatca gggctttcct gaacaataga gttcactaag cgctcgtaat catatgaacg
     7381 gcgaatttca ttgaaaaaca cccagccttc agtgcgttta tcataggcgt ttaaaataac
     7441 atcgccggga cgatagaaat tctttaagaa ccccccattt ggatctaaag caatattttt
     7501 gccgcctcta atgatgctct taaataacag ttcattgaaa attgtggttt taccagtacc
     7561 ggttgtaccg gcaatcgaaa aatgcaagtt ctcagcgtat gtaggtatgg ggatattagc
     7621 cacggttaac tggttgacac ctctttcgcg tgttttatca gcgagtgttc tggcgcgaac
     7681 aagctctgta ccacgataaa tctttttgaa tctttcgcct ttaaacacgc gtgatttatc
     7741 ataaatgata aaagcgatca gaccgccaac accaataaac cagccagcaa ttaaagctga
     7801 ccataaaggc catagcgaaa aagtattctt aaccagatac ggaatcaggt atttagccgt
     7861 ggatggatca ataccgtagg taaattttgc aactagaaac cataccatca ctggaggcaa
     7921 agtaattgca aataaaaatg ctaagcctct ttctctatcg tccatttcag cgctcctttt
     7981 ttggttccca gactttgtag ccgttacgtt caacctctgc ttttgccgct ttggttttgc
     8041 ccggttctgc tatcgagcgc aggaggatta gcgtttcaat agcgagtgat tcatgcaaca
     8101 tcatctgtcc tgccggtggg aattttacgc cagatagcgt ttcggttatt gccttcagct
     8161 catcgcgcag tgggccaaaa tccgcatctg aagcacggtc aaaaagataa tccagtttgc
     8221 gatttacgtc gctcagccgg tcggcaacta ttttcaaccc ggactcccga tcacctgggc
     8281 cagcttcaat gcagcgccgc agataatctg accgattacc tcctgaaacc aggtctatat
     8341 aggccaaaag ttcatctgat acttttgcgg ttattattgg cattcagtcc tcacattgtg
     8401 catttcttaa acaaaaaatt gggatctaac aagctgaaat cttagtatta ccaaagtaat
     8461 aatgcaaact cattataaaa caataggtta ttgggtgttt ttaataccta attattacct
     8521 aatattgacg ctatttattt ttttatcttt taaatcatta tgatagcgtg atttatcgcg
     8581 ctgcgttagg tgtatagcag gttaagggat aaaaaatcat cttttttggt aggagcgatc
     8641 tccgtaggtt aagggtcatt tggctaaaaa gcgtcctatt ctttgatggt catgcttgca
     8701 tgaccatctg agcaaccaaa aactacagat aaactacaga gaaactacag ataaactaca
     8761 aaaaacgatt taccttagcg ttgtcagact actaatagac tacaaggaaa ctacaaagaa
     8821 actacaaaga gactactaaa accgtggcag actactaata gactacaaga aaactacaaa
     8881 taaactacaa aactggattg accccttctt acgagtgttg tagagtcatc ttcatacaac
     8941 ggagggggtt atgaataaac cagcagatct gaaaccccgc aacttatcgg ctgctgtcag
     9001 attgcgccta aatgaaatcg agaactggct ggacagaggg ctaacgcggc atgaaattgc
     9061 tgaaatcctc gacagcgaat acagcttttc ggtaacagcc aaagggcttg agatggcact
     9121 gtatagaacg cggcaaaacc gaaaaaatgt attgcacaat acacatgata agagtagcgc
     9181 gaagggtgca gcggaaagtg tattgcacaa tacacaaccg tctgagcctg aagcgcagga
     9241 aagtgaaaaa gcagagagtc ccggcattat tgataaagag ttcttcaata aaatcggtga
     9301 ggatttcaac cctaagaagt tcaacaaaaa attctgaggt gatttatgaa agtagcggta
     9361 attaattaca gtggcagtgt tggtaaaaca ttaatttcat cttacctgtt agccccgcgc
     9421 ctgactggtg caaagttcta tgcggtagag actatcaacc agtctgcttc cgatctgggt
     9481 attgaaaatg tgaccagttt taaaggtgac gacttctcac gtttgattga ggatattgtt
     9541 tttgaagatg caggcattat tgatattggc gcgtcaaacg ttgaagcgtt cctgatggct
     9601 atgtctcgct ttgacagtgg cgcgaacgaa tttgataaat atgtaatccc ggtgacgccg
     9661 gataataagg cgattgatga aagcctgaaa acggcacaca cgttaagtaa agcgggcgtg
     9721 agcagcaaga aaattatctt tgttccaaac cgtattagtc cagacagtga agtagaagat
     9781 gtgctggcgc cggtgtttga gtttgtcaaa gaaacgaaga ttggcaaaat aagcaagaag
     9841 gctgttattt ataacagtga ggttttcgaa tatctggcgt ttcaccgtat ctcattcgaa
     9901 gtattgaccg ctgaagatcc agaagaattc aaatcccgtg caaaacaaac aaccgatgct
     9961 gacgagcgca aaaaactggc acgccgttat acatacatga aacaggcgat tccggtaaaa
    10021 gctaatctcg ataaagcata tgcggcttta atgggagaat aaaatggaaa agcagccgga
    10081 taaattagaa gttctgatgg actggttttt aggtgacgcg aaggaaatca ccgcaactca
    10141 gaaagaaatg acgcagaaac tttctgagct ttcggaaaag ctggcaaaag acaccgaaag
    10201 tttaggagag acggcagact cttttaaacg ggctttagta gaaaaccagc gttcaattag
    10261 cctggcaatt agtgatgatg ctaaggcgcg cgaggaattt ctaactaaat tccgccgcgc
    10321 gcaggcgtcc agtgctgaga cgtttacccg tcagatcctt tttattacag ctggctgcac
    10381 catcgtgggc gccgcagtag gcgccgcgat agcgatactt ttactgagat aaagcaaacc
    10441 gggcgtgtcc cggttttttt gtcaagcgga gcgcggaggc cgaaggccgg aggcattagt
    10501 ggccgccgcc cgcgtaagcg gggcgagacg ggaaccggct cgaagcgcag cacggcagaa
    10561 cggccccgca ggggcaatgc ccgttttaat tcatcgtgac agtcgcgcgt gaccatcacg
    10621 gggagaaaaa taatgaatga ccgacagcga gaactggccc gtatacgcca ggcccgccgc
    10681 cgcgcgcggc tcaaggaaga atgcacaagc gtgacagtca cgctaacaaa acaggaagaa
    10741 gcaatgttgc aggagctgtg ccgggttcgc cgtcctggac gaacgcctta ttcaacgaac
    10801 gaatttttcc agctgctgct tatccgcaac tggcagcagt ggcaggagca gaagtcacag
    10861 ctgggaaaat gccaggcttg cggaaagctg aaagcggagg gggggtgcga gggtgaacgg
    10921 aaaggcgaaa cctttaactg ctggcttgcc gtcgaagcca atgaactaaa tttgtagtgt
    10981 attgtgcaat acacatttac acagaaacaa aaaccaccgg caattcctgg aaccggatac
    11041 ctacggctat tcctgggtga acggtacttt ttgcacctgg gtgcgctgaa aaagctgaat
    11101 atgcagggtg acgttcgcgt gctgttctgc tttgtagact gaatgcgcca gctatacgcc
    11161 tgactgctta aacctggtaa agttctgcaa ccggcactga ccggaaagca aggcagggaa
    11221 gacctaagcc agaaaccttg actgctcccc gcccttcagg gcggggattg cggatcatgt
    11281 tcttctcttt cagggattca acgcagacaa gaaaggcttt caatttccta tacgtgaacg
    11341 gccgcgcagc ggaaagaaac aagcccggtc aatccgggct tgtttcttta ggcggctcag
    11401 aaatcgccta aaggcccggc ttggccgggc agtcagtgct atttagtttg ttgcagcagc
    11461 tggcttaatt ttgccgccag tgcatacgtc gattggaaag cgccttgcag gcgctgatta
    11521 ggcagctggt tgaacgcttc gaggcaggcg cgcagcaata attctttctg agattcgact
    11581 tcttttttca gttgggaagg ggtggtaact gtagtcatgc ttgctcctta gtgagccgat
    11641 atcggcaatt tttcgggtgg cggtgttgcc tcccgatgat ttaattatcg gtgattatgc
    11701 ttttaaagtc aatacaagta cggaatttat ttacctgttt ttatgcccgt cagggcatgg
    11761 aaggcgaccg cgccggactc caccggacac cgaccgcaaa tcgccggaaa ctgcgggact
    11821 gaccggagca acaggccaac ccccctccct gctaagccat aacccagccc gccgccacgc
    11881 agctgccgca cgtcccccac gggggtgcgc agtgggcgcc gcgcgcctgc gcgcgggtac
    11941 ggcggctcgc ctgcgggtcg cggcgccgta ctgcgagtta gcggccgccg cgcggccggt
    12001 tacgggggac accgcaccgt cacggccagc gccccactga gctgcacaat ccacggataa
    12061 tgcaggagac gaatcatgat aggaggctga aggggaaatg agcggcagca ggggaagggg
    12121 ttgccaagcg gagcgcggag gccgcaggcc ggaggcgtca gtggcagctg cccgcgtgag
    12181 cggggcgaga cgcgtagcgg ctcgatgcgc agcacagcag aacggccccg gaggggtgac
    12241 gtccgggggt tcgcttttaa agattttcga ccacatcagt aaatcgtagt gacaccatga
    12301 agcaaaagta tcgtgcagac cagaatcaac aacagtaaca gcagaccttt ttttcgacgt
    12361 aataaaaccg gccccaaagc gcccgcaaga agcacactca acacgatttc cgttatacta
    12421 atcgtattca taatctctca cgtttccctt tttagaactc tgccacacac agataaaacc
    12481 ttataacaag ctacaaaacc cgttattcag acgcggtaat gcctagtttt tttgccagta
    12541 tttcagatga caaagaaacc cttatccact tcccggttac aaggtgaatg attgtggctt
    12601 catgcccttt aacagagtgg gatattaact cacgctgaat gatatgcgtc tctccatcat
    12661 ttcccgtcac ggcaattagg ccctctgtag aacaggggtt gatactacta atgttggtgt
    12721 tgttttcggt tttgttcagc atcgctgatc ctcaaatatc ggtttgtgtt acgtctgccg
    12781 ctttgcgctg gataagcgac ttaaagaaat ccgacgcctt cagaatatcg ctatcctgga
    12841 agtcgggaaa tgtcgcttct gtcagctcct gcgccgtacc tgcccgtata acggtttcat
    12901 cgcggatcat cgttcgctta acgccatcag cctgtttttt gctgaaggag tgccggaaaa
    12961 taatcgcgta ttggccgccg ctatcctgat gaacagaagt atcccagcga tgattaccct
    13021 gtttacgata gtggtgatag atttgctggc cgtagcgctc ctgatcggaa ttacggtaat
    13081 cgaacattaa cagttccaaa agcattaacc gatctggcaa ttgccaggcg gtagggtgtt
    13141 gaagtgtcgc taacatagtt tcccctgagc gtgacagtca cgataaggcg ggctttgccc
    13201 gcctggttat cagttaatca atggcacgat aaatacgatt ctggctttcg ttctccagcg
    13261 tattaacgta ctcccgcaac aggtgatacc ggttagccat cgtttcgttc agttcggctt
    13321 tgccttcttc atatgccagc ccgcaaaagt aactgtaggc atacagacaa acaataatcc
    13381 ctacttcgcg cgcgctgcat tcaccttcaa aatagttagg taacgagagc caaagaggtt
    13441 ggggcgcttc cataaaaaac gcgccattgc tggcctgaag gtattcccaa taccctccct
    13501 ggtagtcttt agcgtaacga ttcagaaagg actgaatgaa gtgatctgcg ctgaagaaag
    13561 cgccacgaaa tgccgcaggc atgaagttca tgcgggcgtt ttcagaaatg tagcgggcgg
    13621 tgatttcgat agtttccatg atacttcctc ttaaagccga taccggcgat ggttaagcgg
    13681 caggcacatc acctgccact ttttaattat cgtacaatgg ggcgttaaag tcaatataag
    13741 tacggattat atttacctaa ttttatgccc gtcagagcat ggaaggcgac ctcgccggac
    13801 tccaccggac accgggggca aatcgccgga aactgcggga ctgaccggag cgacaggcca
    13861 ccccccctcc ctgctagccc gccgccacgc ggccggttac aggggacact gagaaaacag
    13921 aaagccaaca aacactatat atagcgttcg ttggcagctg aagcagcact acatatagta
    13981 gagtacctgt aaaacttgcc aacctgacca taacagcgat actgtataag taaacagtga
    14041 tttggaagat cgctatgaag gtcgatattt ttgaaagctc cggcgccagc cgggtacaca
    14101 gcatcccttt ttatctgcaa agaatttctg cggggttccc cagcccggcc cagggctatg
    14161 aaaagcagga gttaaacctg catgagtatt gtgttcgtca cccttcagca acttacttcc
    14221 tacgggtttc tggctcgtca atggaagatg gccgcatcca tgatggtgac gtactggttg
    14281 tggatcgctc gctgacggcc agccacggct caatcgtagt cgcctgcatc cataatgaat
    14341 ttaccgtgaa gcggctactg ctgaggccca gaccctgcct gatgccgatg aacaaagatt
    14401 ttcctgtgta ctacattgac ccggataatg agagcgttga aatctgggga gtggttacgc
    14461 attcccttat cgagcatccg gtatgtttgc gctgattgat gtcaatggca tgtacgccag
    14521 ctgtgagcag gcatttaggc cagatctggc aaaccgagca gtggccgttt tatccaacaa
    14581 tgacggcaac attgtggccc gtaattacct ggcgaagaaa gcgggcctga aaatgggcga
    14641 tccgtacttc aaagtcagac ccataatcga gcgtcataac atcgctattt ttagctctaa
    14701 ttacactctc tatgcctcca tgtcggcccg gttcgcggcc gtagttgagt cccttgcaag
    14761 ccacgtcgaa cagtattcaa tcgacgagct ttttgttgac tgcaaaggga taacggccgc
    14821 catgagcctt gacgctttcg ggcgccaact gcgcgaggaa gtcaggcgac acacaacgct
    14881 ggtatgcggg gtcggtattg cccgtactaa gacgctggcg aagctgtgta accacgctgc
    14941 aaaaacatgg cccgctactg gcggggtggt tgctctggac gatggcgcca gactgaagaa
    15001 attaatgagc atcctgccgg ttgcggaagt ctggggcgtc ggccatcgta cagagaaagc
    15061 actcgccaca atggggatca aaacggtgct ggatttagcc agggcagata cgcgcctaat
    15121 ccgtaaaaca ttcggcgttg tgcttgaaag aacggtacgg gagttgcgcg gcgaggcttg
    15181 cttcagcctg gaagaaaacc ctcctgcgaa gcagcagatt gttgtgtcgc gctcattcgg
    15241 ccaacgcgta gaaaccctga cggacatgca gcaggctgtc accggatttg cagcgcgcgc
    15301 agctgaaaaa ctgcgtaatg agaggcaata ctgccgcgtc ataagcgtct ttatccgtac
    15361 cagtccttat tcagtgcgtg atacacagta tgccaatcag gcaaccgaaa aactgacggt
    15421 ggcaacccag gacagccgca cgataattca ggcagcacaa gccgcgctgg cgcggatctg
    15481 gcgggaagat attgcgtatg caaaagcagg ggtcatgctg gcagatttta gcgggaagga
    15541 ggcccagctt gatttattcg actctgctac gccttcagct ggcagcgagg ctttaatggc
    15601 tgttcttgat ggtataaacc ggcgtggaaa gagccagctt ttttttgcag gccagggcat
    15661 cgataactcc tttgccatgc gtcgtcagat gttgtcacct gattacacga cagactggcg
    15721 ctcaatacca atagccacca tcaaataatt accggcgccg tacacgggcc ggttaacccc
    15781 tcaaccggcc gaaacaagtt tcggcacggt ttcgcggttt tcggtaaaag ccgtttcctc
    15841 tgtataaaag atcagctaaa ttatgtgtat tgcacaatac atatatgtga ggttagcagt
    15901 gaatttgcct acgcccgaaa cctacgatga acttcagaga gcctacgatt ttttcaatga
    15961 gaagctattc agcaacgagc tgccgccatg cctgataacg ttgcagcgtg agaagcgaac
    16021 gtatggctat tgttccttta agcgtttcgt cggccgtgag agtgggtaca cggtagacga
    16081 gatcgctatg aatccggtgt atttctcgat cagaaccata aaggccacgc tttcaacact
    16141 ggtgcatgag atggttcatc agtggcaatt ccattttggc gagcctggcc gccgtggcta
    16201 tcacaacaaa cagtgggcgg cccggatgga acgggtagga ctaatggctt ctgataccgg
    16261 cgaaccggga ggcaggaaag tgggccagag catgacccat tatattattg ccggtggccc
    16321 tttcgatatg gcctgtgatg aactgctgac aggccatttc cggctttcct ggatggacag
    16381 gtttccgcct taccagccta agcctggcgc tgtgctaagc cctacaggaa aaggctatat
    16441 tgacgacgag gaagatgata gcgaacacga acaggaggtg gaggaagggc gcgacccggt
    16501 tgaactcgac gacgagatca tagaggccat gcgatttgta accccaccgc ctgaagcacc
    16561 ggtgaacaaa acaaaccggg aaaagtacag ctgcccggtg tgtcatatca atctctgggg
    16621 taaaccgggg atagtggttt actgtggtgg cgagcactgt aataaagccg cgttagtagt
    16681 cttaaaataa agtcctttcg gactttattt tttttccatt tccgaggtcg tgatgttatt
    16741 aatgctgtac ttcgcggctt cttttaaaac agtttcagca aggcttgctg gtatccagac
    16801 ctgaactaat tttaatggtt cgccgttctc ggctttaaga gtggtgttct ggtacaaatc
    16861 ccagattcgc ttaacggtgc tggaaatgtt ttgcttggaa cggcctactc gcgtggctac
    16921 gtctgatgat ttctcacctt tgacaagcac ggaatagcca atatctgttg tgatgtgtgc
    16981 aaaggaagcc atttgcggca gcagctgttt ccattctgtt tctgaaattc tgtttttctg
    17041 agccatctgt ggcgcctccg tagttttggt tacagaaagg atatactcag aataaacagg
    17101 ggtcaataca agtacgattt ttataaactt tattttattt gagggtgagg cccggtgcgg
    17161 cagcagcgcg ggcctcgatg gtgccgcgaa ggtgctggcg ccatgctcgg attaaaacat
    17221 gaaccgtgaa gaactgcgaa acttgttttc gcggttctga ggggttgacc gagccgcgaa
    17281 gcggcgctgg taagcgatga tatgcacata tccacaggca tatttttaaa aggtatttta
    17341 tagatttttt atctttttaa agtcttttag agctatataa ctcattgatt taaaatcata
    17401 aataagtgtt atctctggga atccgcccac cttgttatgg gaattggccc accttactat
    17461 gggaaacagc ccaccttact atgggaatta gcccaccttg ttatgggaat tggcccacct
    17521 tagacgaaac tgtaaaaaat gtatttactt gtttgaactt tgtggtagtg tggagagtaa
    17581 tttttaaccc acaaaggcaa ggcgcatgga taagttgctg aacaaaaaga taaaagttaa
    17641 gcagtctaac gagcttaccg aagctgctta ctacctctcg ctaaaagcaa agcgcgttct
    17701 ctggttatgt cttatgcaga cgtatttcac agcttcagta agcgaagatg atgatgagat
    17761 ggctgtactc ggtgactcta ctttcaaagt aaaggtggct gactatcagc aaatttttca
    17821 ggtaagccgt aaccaggcta tcaaggatgt taaagaaggc gtgtttgagt taagccgttc
    17881 tgcggtaatc ttttacccga aagaggggcg ttttgactgc gtcgcgcgcc cctggctaac
    17941 agaggctggc agccgatcag ctcgtggtat ctgggaaatc gaatttaacc ataaactcct
    18001 gcggtacatt tacggcctga cgaaccagtt caccacctac tcgctccgcg attgtggcag
    18061 tcttcgaaat ccccggacga tccgccttta tgaaagtctt gctcaattca aatcttcagg
    18121 cttatgggtt actactcatg cttggttaaa tgaccgtttc cttttgccgg aatcccaaca
    18181 gaagaacttg gcagagttga aacgatcttt ccttgatcct gcactcaagc agataaatga
    18241 gaaaacacct ttacttgcta agtatagtat tgatgattca ggaaaatttc tgttctcaat
    18301 aattgataag caaaatcccg tctgacataa atcagcacac atgagcctgt catttgacaa
    18361 atttttgtca tgaagatggg cgaatttcca cacagcaccg gcgcccggca agatgggcgg
    18421 attcccacac gacagcggcg cccggcaaga tgggcggatt tccacactac agcggcgccc
    18481 ggcaagatgg gcggattccc acacgacagc ggcgcccggc aagatgggcg gatttccaca
    18541 cggcagcggc gcccggcaag atgggcggat ttccacacgg cagcggcgcc cggcaaggtg
    18601 ggcggattct cacgcggcag cggcgcccgg caagatgggc ggatttccac acggcagcgg
    18661 cgcccggcaa ggtgggcgga ttctcacgcg gcagcggcgc ccggcaaggt gggccgattc
    18721 ccacgcggca gcggcgcccg gcaaggtggg ccgattccca cgcggcagcg gcgcccggca
    18781 aggtgggccg attcccacgc ggcagcggcg cccggcaagg tgggcggatt ctcacgcggc
    18841 agcggcgccc ggcaaggtgg gcggattccc acacggcagc ctcgcccggc aaggtgggcg
    18901 gattcccaca cggtagcctc gcccggcaag gtgggccgat tcccacgcgg cagcctcgcc
    18961 cggcaaggtg ggcggattcc cacacggcac cggcgcgcgg caaggtgggc ggattcccac
    19021 acggcaccgg cgcgcggcaa ggtgggccga ttcccacacg gcaccggcgc gcggcaaggt
    19081 gggccgattc ccacacggca gccgcgcccg gcaaggtggg ccgattccca cgcggcagcc
    19141 tcgcccggca aggtgggccg attcccacgc ggcagcctcg cccggcaagg tgggcggatt
    19201 cccacacggc accggcgcgc ggcaaggtgg gcggattccc acacggcagc ggcgcccggc
    19261 aaggtgggcg gattcccaca cggcagcggc gcccggcaag gtgggcggat tcccacacgg
    19321 cagcggcgcc cggcaaggtg ggcggattcc cacacggcag cggcgcccgg caaggtgggc
    19381 ggattcccac acggcagcct cgcccggcaa ggtgggcgga ttcccacacg gtagcctcgc
    19441 ccggcaaggt gggccgattc ccacgcggca gcctcgcccg gcaaggtggg cggattccca
    19501 cacggcaccg gcgcgcggca aggtgggcgg attcccacac ggcaccggcg cgcggcaagg
    19561 tgggccgatt cccacacggc accggcgcgc ggcaaggtgg gccgattccc acacggcagc
    19621 cgcgcccggc aaggtgggcc gattcccacg cggcagcctc gcccggcaag gtgggccgat
    19681 tcccacgcgg cagcctcgcc cggcaaggtg ggcggattcc cacacggcac cggcgcgcgg
    19741 caaggtgggc ggattcccac acggcagcgg cgcccggcaa ggtgggcgga ttcccacacg
    19801 gcagcggcgc ccggcaaggt gggcggattc ccacacggca gcggcgcccg gcaaggtggg
    19861 cggattccca cacggcagcg gcgcccggca aggtgggcgg atttccacac ggcagcggcg
    19921 cggggccagt gggattcagg agaataggtg ttttaccgaa tgccctgacg aggcgtaaaa
    19981 aaaccgcttg gcggcggcct cataaagcag aaaacccgct caaggcgggt tatctgctct
    20041 gtagcctgtg atgcttcgcg ggcatccggc atacagcgag gtgaaattct tcttttggca
    20101 tgttaattat acgtctaacg cggcatatga tcaaacctgt attaaataag ccactgtacc
    20161 gtttataatg ctctcagatc aaagaggtaa agcccgttta gccgcctgtg tgatgagcca
    20221 gttcagactc ttcaaaatcg aatttggtac taaacaggac ccgaaccgtg ggcaagcaca
    20281 cggcaacggt atagccctct tccggtttcg cacccggaag cctgggcggc agcgtggtga
    20341 aattcttctt ttggttaagt gaatggcata accggatggg cggattagag gaaaggggat
    20401 tgcctagtaa cctacgcgcc acagagatgg aggtgcgggg aatgattgag ctgattatcg
    20461 ctattctgac cttaattgcg gctgtattgc agttgatcaa ctggttcctt taatggtgcc
    20521 ggagtctgtg aaggtgaaag cctgaacggg caaaactgaa aggtttatag ccgtccttcg
    20581 gggcggcttt ttttcggcaa aattagggtt ttaccgaata atgcagagtt ttaaggtgag
    20641 aatttgcaga cttggcgttt taccgaacat agatactccc taggctgata ggtgcattag
    20701 ttatcaccct acctgaacat attgtaaaag atgtcagtct ccagtgactt gtgtactatc
    20761 aactgacaag actcttacac gcaacgcagg gggatggagt tttatgctta gaaaaataat
    20821 caggggtagc ggattcactc agtcagaaga aaaactgata gagttcgctg atgatgcttt
    20881 ttttggtctt tggtcttatc ctaatgttta tagcgatgag ggttactcta aaaataaaat
    20941 tgggaaagaa gttagtgact tattagttat ttttgataaa gatataataa ttttttccga
    21001 taaagctatt acatacaata aaaacaaaga tcctaaggtt gcatggcaga gatggtttaa
    21061 aaaatcagtc atacagtctt gcacacagtt atttggcgca gagaagttta taaaagatca
    21121 tcccgaaaga ctttttgttg acaaagaatg ctcagttaac ctccccatta aaatagataa
    21181 ttcttttaat tttcatttgg tggccgtcac taataatatt tcagatccgg cgatctcgta
    21241 ctttgacaaa atagaaaaag gcagctctgc tactttagtt aacatatttc ctttaaacgc
    21301 ccatcaatgt ctagaaaatc cattttgtgt cggagacgtt tatcctgata agacttttgt
    21361 ccatatactt gatgagactg ccctaaaact actgttaacc gagttaaaca cagcaactga
    21421 tttcattggc taccttaacg aaaaagagag ggttgtaaga gaaagaacat tattggtcag
    21481 cgctggggaa gaagagactc ttgctgctta cattatgggt gataaaacca taatatcaaa
    21541 agaaattatt ggaaacgatc aagggatgac cataccggaa ggtgaatgga aaaactataa
    21601 aaccactttc aattatcaat atcagctctc aatgaaaaag ggtagcgttt tctgggataa
    21661 cctaatccac aacttctcga caagtatatt gtcagctaac gttggttttt ttagtgaaat
    21721 tgaattttct acacatgaat taggtgttag agaattagcc aaagaaagta ggcaatctag
    21781 atattacctt tcaaagaact ttaaagagaa attaaaaaca actcagcctc atctaagaac
    21841 gtcaagaatg gtcgaatcaa tcgatgagcc tggaaagttt tacttattcc ttttttttcc
    21901 taacgatagc aagttgagtt actctgatta cagaattcaa cgtatatctt atataaatgc
    21961 ttatgctgag gttgccttta ataaatacag acatattaaa aaattaatta ctattgcaac
    22021 agagccgcaa aatacagaag gaagatctga agacctaata tatagcatat ccccagagaa
    22081 atttaccaaa gagcaaaatg aaaaagccaa aagattatca agagaataca aaatactaag
    22141 tgatttttta cctactaaaa cgacaaagag cgataacttt aaatcagtta tatcaaaagg
    22201 tgaaaaaata gggcggaata caccttgtcc atgtggctcc ggtgttaaat ttaaaaagtg
    22261 ccatggtgcg aataattagc attattgtat gtataacggt aatggcgcgg cagagaaacc
    22321 ggcgcgttct gccctagtgt tggcctgcgg gttcccccgc acccgctgta tgtagtatcg
    22381 gcagcatctg agaaaaccac tacatgtagt tatcagcgcc acaacggcgc ggggacgagt
    22441 gcggttcgga aaaattgggg ttttaccgaa tccggcaaaa gattgcttcc tataacgtcc
    22501 gcttctggca cacagcagcc gttaagatgt aaggccttac gccaactaaa tctaatggga
    22561 cagatttagt tggtgatggt caagtaatct gcaaacggtc accaagtaat ctgcaaacgg
    22621 tcaccaagta aaatgcaaat gggtagtcaa gtccgatgca attacgcacc cggcaaggtg
    22681 ggccgattcc cacacgacag cagcgcccgg caaggtgggc ggatttccac acggcagcgg
    22741 cgcccggcaa ggtgggcgga tttccacacg gcagcagcgc ccggcaaggt gggcggattt
    22801 ccacacggca gcggcgcccg gcaaggtggg cggattggca ctgttgcaaa tagtcggtgg
    22861 tgataaactt atcatcccct tttgctgatg gagctgcaca tgaacccatt caaaggccgg
    22921 cattttcagc gtgacatcat tctgtgggcc gtacgctggt actgcaaata cggcatcagt
    22981 taccgtgagc tgcaggagat gctggctgaa cgcggagtga atgtcgatca ctccacgatt
    23041 taccgctggg ttcagcgtta tgcgcctgaa atggaaaaac ggctgcgctg gtactggcgt
    23101 aacccttccg atctttgccc gtggcacatg gatgaaacct acgtgaaggt caatggccgc
    23161 tgggcgtatc tgtaccgggc cgtcgacagc cggggccgca ctgtcgattt ttatctctcc
    23221 tcccgtcgta acagcaaagc tgcataccgg tttctgggta aaatcctcaa caacgtgaag
    23281 aagtggcaga tcccgcgatt catcaacacg gataaagcgc ccgcctatgg tcgcgcgctt
    23341 gctctgctca aacgcgaagg ccggtgcccg tctgacgttg aacaccgaca gattaagtac
    23401 cggaacaacg tgattgaatg cgatcatggc aaactgaaac ggataatcgg cgccacgctg
    23461 ggatttaaat ccatgaagac ggcttacgcc accatcaaag gtattgaggt gatgcgtgca
    23521 ttacgcaaag gccaggcctc agcattttat tatggtgatc ccctgggcga aatgcgcctg
    23581 gtaagcagag tttttgaaat gtaaggcctt tgaataagac aaaaggctgc ctcatcgcta
    23641 actttgcaac agtgcccgat catcggcacc agtacctgct tgaggtcacc atagcggcgc
    23701 gaatgagcga gccagacatc tccggaacga aaagcatccc ggaggtgaaa gagtaccgcc
    23761 acttcccaaa gacgggtatc tcctttttcc tgagctcgta aatgacggtt ccatttggag
    23821 ctgggccgca ggaaacgcct ttctggcgat gcaacacctt tcatctctcc gatcgacaaa
    23881 gctgctgcta ccaatggtcc ggcgaccggc gcggcttcga gcttcagaca gcgcaacatg
    23941 cggggcgcat aacgacgaaa gcgatggtat ccctgcccga catatgcaag aggctcatcg
    24001 gctagcgtgt tgctgagttg agtccctgtc gctaccagtt gagcgagccg gtcccatgca
    24061 accgaactgg cgacagccat ctccagcggg gttccgtcac tgcgggcctc aagcaacgaa
    24121 gctcccagcg cggtgaaggt acggatcgta tccgtgagtg tggctttaga gccggaaatt
    24181 gtttcgtcat gctggcgctt cgcttcccgc caggtttttc ctacgatcct gtcatgggtt
    24241 tcgactatgg catcagcaat cgccgcttcc cactccacaa cacagacggc aaggatcgcc
    24301 cagcggcggt ccgaagtgat gtcacgcaaa ccgtcggtga agtagcgttc accctgccga
    24361 cgcagccggg caatgcgatg ggcaggtatg ctggccaaag cactatgatt gatattcagg
    24421 gtacgcagaa attcgagcct gtcgagcaaa cggttagcag cagccgagtt gttaccaacc
    24481 tcgaagttgc gaagccagat gaaacgactg atattgccgg cgagcatttc actcagaagt
    24541 ttgtccaggt gatcgcgaac atccgctgtt aaattttccg caatccgcgt ttcaatccgc
    24601 cgctcagcgg cgaccagagc atccgcgcac aagcgctcga ttgtcgatac tgcgggcaga
    24661 atggtggaag tttcccgaca ccgcacaata aaacgatgag caagatcctc gtttgatctg
    24721 gcatcttcgg cctggccgaa agtccactcc cgcagatcac gggcaccacg gcccgtgaag
    24781 gtcttgtagc cgtaaatttc gcgcagcgtg tccatgtgct gctgacgggt ttggcgccgt
    24841 gtggcataag tgagaagcgc atcagccgga actccaagct gagcaccgac gaaggaaagg
    24901 acttcacgcg ggatcatctc accaggagcc agtgcacggc ccggatatcg taaggcacaa
    24961 agttgcaggg caaagccaat cctgttttcc ggtctgcggc gctgcctaat gttttccagg
    25021 tcatcatcgc ccagcgtgta gaacttcagt agcgacagtt cgtccgtggg cagatcgaac
    25081 agcgctgctc gctgccgttc ggtgaaaata tggcgtcgtg acatacaaat tcgtcccttt
    25141 tgaagtatag tctgttttgg acaacagcca gcccatataa atcagggcgt tccgatacaa
    25201 aaatccagga gggttcaatt gggacatcgt gccgccattt actgccgggt ttcaacagcg
    25261 gatcagtctt gtgaacgcca ggaatttgat ctgcgagcct tcgccggccg tgccggctac
    25321 gacgtggtgg gaatatttaa ggaaacaggt tcaggaacta aactcgaccg ggccgagcga
    25381 aagaaagtcc tggcgcttgc ccagtccaga caaattgatg caatcctggt cactgagctt
    25441 tcccggtggg ggcgctcgac gctcgatctg ctcaatacgc tacgtgaact ggagaactgg
    25501 aaggtttccg tgatagccat gaatggaatg gcgttcgatc tttcgtcgcc gtatggacga
    25561 atgctggcga cgtttctttc cggcattgcg gagtttgagc gggatctcat cagcgagcgg
    25621 gtcaagtcag gccttgctgt tgcgaaggca cgtggtaaga ggcttggtcg tcaggccgga
    25681 gtgcgaccaa aatcagaccg acttttgcct aaggtggttg cgatgagggc cgagggacgc
    25741 agctatcgct ggatcgcacg cgagctcggt atcagcaaga ataccgtcgc tgacatcgtg
    25801 caacgacaca gagctaacgc ttagggtgtc atttcgccct cagccggaac cgacccctat
    25861 aatatctgcg ccagacgacc tttttacatg taaaaatttg atgcgagcga atctgttgac
    25921 tcaaataatt tgactggaag cctagtcgat gcgcagtggc tcacatttag ccgtagtggg
    25981 ctggtgagat acaaataaat cgttgttgag gtataaataa ttttgctttt tttagttcaa
    26041 taataatcgt aagttgtcag tagcagaaaa gatgattaat tattgcctgt gttagtgaaa
    26101 cctaatttat acagtgatcc ggtattttaa ttctggtgaa taataaaatt acggcggtga
    26161 tgtttttatg gaaatagtcg tgttattgcc attgttggta atgctgatac tcgttttgcg
    26221 aaataagcat atgattctgg caggactggt gggcggacta accgcgatgc tggttggtgg
    26281 catcggtttt tcgcaggcaa gtaagatcgt tatgacatca attcccggga tgacgggaat
    26341 tatcaccccg gttatctatt ctgctgtggc gttggtactg gctaaactcg gtggttttga
    26401 agcgttgctc ggtctgagtc gcagagtgtt tggccgaaag caatatctca ttgcggcggc
    26461 gattgtactc actcaggcgt tagcaactta tgccgcaggg cttggggcgg gtaataccat
    26521 ggtaaccggg cctcttgcgc tggcgattgt aggtgctgtt ccacagctga tagcgggcat
    26581 ggcaattgtg actgccgcga gctttatgac gtcaccttca ggggccgatg cggccgctat
    26641 ttcaaaaatt gccaacattg aaattgcaac ctatagcgat acgatgttcc ccattaccgt
    26701 ctgcttgtgg actttgggaa tgactatcgc tgcattcggc gtctggaaaa gcggaagcgt
    26761 cctgcaggat gaggatacga tgtccgatgt tacgctgaaa gaacagttaa ttaaggtcat
    26821 gcctcccgta tattttctgg tagtcgttgt ggcaggcaaa aacttgaatg agttattcga
    26881 ttattcgctg tttagcccga tatttaatat gttcagtacg ttgatgctgg gttttgcagt
    26941 aacacgtcag tctcccggta agctggctga agaactggta cagaactctt ctttcctgct
    27001 aacaaaacta ttcgcaattg gcattttcct cggttttatc aacatactgg cggaaattgg
    27061 tacgttcacc tacattgctg aatttattaa atcatcaccc gcctttgtta ccgtacccgt
    27121 ggctgtattt attgcttttt gcatctcgat tccggcagga ggatacagcg tgggggtcag
    27181 taccctggtc atgccgatta tggtggagtc cgggctttct attacacaaa ttggtctggc
    27241 ggcacttgct gtaggtgtgg gcacgcaaat gagcccggtt caaatcaacg tggcttcact
    27301 gtcacagtca ttcaagctgg atattcagcg aattgttaaa attaatgcac cttatatggc
    27361 tggcgttgcg gcgatactgt gcatcatggg attcttctta taaaacatct tacaaaactt
    27421 gctgtccctg gtatctgaaa aagaggaaat acactatgca aaaagttgaa gtgttccgta
    27481 ttccaactgc atcgccggat gatgtatctg gtctgaaaaa tttgattgag aatggtagtg
    27541 ttgatccacg tgatattatt gctgtattgg gtaaaactga aggtaatggt tgcgttaacg
    27601 actttacccg cggttttgca acgcaaagcc tctctatctt catggctgag caattagata
    27661 tgtccgtcag cgccgtacag gagcggatcg catttgtcat gtcaggcggc acggaaggcg
    27721 taatgtcgcc ccatctgacg gtgtttaccc gcaaagaggt ggatcaaccc gcaaaggaag
    27781 gtaaacgtct ggcagccggt attgccttta cccgggattt tctcccagaa gaaattggca
    27841 gaatggcgca ggtgaaagaa gtcgctgaag gggtgcgtat tgcgatgaaa gatgctggca
    27901 ttaccgatcc gcaggatgtt cattttgtgc aaatcaagtg tcctttactg acggcagatc
    27961 gtattgagga cgccagagtg cgcggtcaaa ccgttgctgt tcatgatacg tataaatcaa
    28021 tggcctactc cagaggggca tccgccctcg gcgtcgcgct ggccctcggt gaagtgtcag
    28081 aagatgcgtt gaacgataag gtcatttgtc aggactggac gctttattcc ggtgtggcgt
    28141 ctacttcggc aggtgtggaa cttctgaagg atgaaattat tgttatcgga aacgctgaaa
    28201 acacgaccag cgatctgcgc atcgggcatg cggtgatgca ggatgctatt gatatcgatg
    28261 ccctgtttgc cgctatgcgt gaagccggtc ttgaatttga cggtctgccg ccgcaggaag
    28321 agctggatcg gatcgtaaat gtgttggcca aggctgaagc aagctccaca ggaacggtgc
    28381 ggggaagaag aaatacgatg caggacgact ctgatatcaa ccatacccgc tcggcccggg
    28441 ccgtggtcaa tgcagccatt gccgcaatta cacgtgaccc gctcgtgtat gtctccgggg
    28501 gggctgagca tcaggggcca gatggcggcg gtcccattag cgtaatcgcg aaagtgtaag
    28561 cagcctggca agggggaacg agcggttaat cacgctcact cctgcgccag aacaaccgcg
    28621 gggcggccct gccgggcagg gagcgagccg gacttggttt tacgatgaga ggtgatgcac
    28681 atgaataacc actttgtcgg aattgatgag aagcccccgt ttctatcttt gctgttaatg
    28741 gggattcagc acgtgctggt gctgttctca ggtctggtag ccgtaccgtt ggtggtgggc
    28801 atggcgcttg gtctgcccag tacggatatt actgttctgg tccagggcag cttgattgtt
    28861 agcggtactg gtacgctgat tcaatgcctt ggtttaggac atctgggatc ccggttgccc
    28921 atttgcatgg gctcggcgtt tgtcttcatt gcacccagta tcacggtggg gtcgcagatg
    28981 gggatccagg ccgtgtttgg cgcatccatg gtgtgcgggt ttgtcgcctg gatcctcagt
    29041 ttttttattg gaagagtgca gaaactgatt cctccgctgg tgaccggaac tattgtttca
    29101 ctgattggta tcaagctgct gccgctggga ttcacctggc ttgctggtgg gcatagtgaa
    29161 ctttatggca agccggtatg ttttctgatc ggcggcgttg tgctggtggc attactggtt
    29221 gccagccagt cgcgaaaagg cttgttatca tcgttttccg tcattattgc cattatgctg
    29281 ggatatgttg tatcggcact gctcggcatt cttgacctcc accacgtgca ggatgcttcc
    29341 tgggtctctt ttcctgattt gctgcatttt ggttggccga ctttttcgta ttcggccatt
    29401 gtcatcatga tgattgctca acttaccgcc gtactggaaa gcattggtaa tacatacggt
    29461 acgggagctg cggtacgcag agagatcacg cataagcatt tgtctggcgc aatctcagtc
    29521 gatggtatcg gctcgattgt cgcgccgctg cttaacggtt ttcctctgac ctgttttgcc
    29581 cagaatatag gggtcatcag tatcactcgc gtggcaagcc gctatgtggt tgcctcagcg
    29641 ggtgtggttc tgattgcact tgggttgatt cccaaatttt cagccctggt cgcgggaatg
    29701 ccggcaccgg tgctcggtgg agcgtctctg attatgttcg gctctatcgt cgggtcaggc
    29761 gtcgcccaga ttaaggattc aggaccgttc gaccagcgag cagccatggt tttttcaacc
    29821 tctctcgcac tcggactggg gtttggcctg gcgccgaaag acgcttttga tgccttttcg
    29881 ccatcgctgg tcgtgctcct ggagtcgggt gtggcgattg gtggaatggc ggcaattata
    29941 ttgaatctgg ttcttccgcg atcacctgaa ccatccgtta gctgaaatcg cgagggttga
    30001 agtttattta tttaattcat ttttcgcttt tattgaattg ttctgccgta taaatgatat
    30061 tttatgattc cagtctctgg caggtattta cctgaccaat ggaagatggc caattattta
    30121 tttttacttg tggtggatat aaggttgaat cattatcggt aattctccga tggaggtgaa
    30181 atatgacatc tttaacactg attcccgtta cggtcgggta tttggccatt gaccgtctga
    30241 acgatgccgg gaatcaacaa ataaatgttc acagctgctt tacaaatacg atgaatttat
    30301 tgttgtctga tggtgaatta ctgatactgg cttcggagca caccggttta aatcatcctg
    30361 atactattat tgttagcgta ccggcgaact gggattggcg ttgtaccggg cgtgcgggga
    30421 ttacgttcgg tgatggtata ttcagcaacc cggtttggca aatggatata cgccatgtta
    30481 aacgttggca gcaaacagac ttatatccat taataatgac ggaaactgaa aggaaatata
    30541 cgtttcttgc tgagcaatta aaagtg
//
