LOCUS       NZ_CP133003             6585 bp    DNA     circular CON 17-APR-2024
DEFINITION  Staphylococcus epidermidis strain SEA37 plasmid unnamed4, complete
            sequence.
ACCESSION   NZ_CP133003
VERSION     NZ_CP133003.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36827138
            Assembly: GCF_038116975.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 6585)
  AUTHORS   Puls,J.S., Winnerling,B., Power,J.J., Kruger,A.M., Brajtenbach,D.,
            Johnson,M., Bilici,K., Camus,L., Fliesswasser,T., Schneider,T.,
            Sahl,H.G., Ghosal,D., Kubitscheck,U., Heilbronner,S. and Grein,F.
  TITLE     Staphylococcus epidermidis bacteriocin A37 kills natural competitors
            with a unique mechanism of action
  JOURNAL   ISME J 18 (1) (2024)
   PUBMED   38470311
REFERENCE   2  (bases 1 to 6585)
  AUTHORS   Power,J.J. and Heilbronner,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2023) Microbiology,
            Ludwig-Maximilians-Universitaet Muenchen, Grosshaderner Str. 2-4,
            Martinsried, Bavaria 82152, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2022
            Assembly Method                   :: nf-core:bacass v. v2.0.0
            Assembly Name                     :: SEA37
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_038116975.1-RS_2024_04_16
            Annotation Date                   :: 04/16/2024 23:46:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,442
            CDSs (total)                      :: 2,358
            Genes (coding)                    :: 2,298
            CDSs (with protein)               :: 2,298
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 37 of 60
            Pseudo Genes (incomplete)         :: 39 of 60
            Pseudo Genes (internal stop)      :: 20 of 60
            Pseudo Genes (multiple problems)  :: 27 of 60
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP133003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6585
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="SEA37"
                     /isolation_source="Nasal cavity"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="unnamed4"
                     /geo_loc_name="Germany: Bonn"
                     /collection_date="2013"
     gene            complement(354..959)
                     /locus_tag="SHJJP9001_RS12160"
                     /old_locus_tag="SHJJP9001_002425"
     CDS             complement(354..959)
                     /locus_tag="SHJJP9001_RS12160"
                     /old_locus_tag="SHJJP9001_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="WP_077431415.1"
                     /translation="MKRLEEIEKREYERNQRHDQLLTSIETTASNFNQATDFTQKRFIS
                     AARHYIERINNDNLKQDFHTAIQKELEDVKTDTQNVVKEVQNNQSELRQANNNYKKMID
                     ERMKSNAIVIKQYDQVIHRLTKGITAMFFIVALVMVAFLVISPLGDWLGVQHFYEWLNH
                     VLKTGHSAWRYFMLVFYLVPYILFGVLIYAILKAYERL"
                     /name="mobilization protein"
     gene            complement(862..1872)
                     /locus_tag="SHJJP9001_RS12165"
                     /old_locus_tag="SHJJP9001_002426"
     CDS             complement(862..1872)
                     /locus_tag="SHJJP9001_RS12165"
                     /old_locus_tag="SHJJP9001_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_002498904.1"
                     /translation="MATTKLSATKSTSRAINYAEKRAVEKSGLNCDVDYAKSSFKAARE
                     LYGKTDGNQGHVIIQSFQPGEVTPEQCNQLGLALAEKLVPNHQVAVYTHADTNHVHNHI
                     VLNSIDLNTGKKFNNNKQALRDVRAFNDEVCRAQGLSVPEKDTARLRYTQTEKAIADPN
                     TTSTAQYSWKDDIREAIDQSTATNMEEFQKHLNQHGITIERVTPKSITYRHLAENKKVR
                     GRKLGEDYNKGGIQHGFERQIQRRQQQKHKSDTNFQPKRSTSNRHESTERDTGVTQSDW
                     DQFAQDTNELERRRQAAESARLVDEKARRDREKRVREKPTSRPIINIDRDHGLEL"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(2038..2424)
                     /gene="mobC"
                     /locus_tag="SHJJP9001_RS12170"
                     /old_locus_tag="SHJJP9001_002427"
     CDS             complement(2038..2424)
                     /gene="mobC"
                     /locus_tag="SHJJP9001_RS12170"
                     /old_locus_tag="SHJJP9001_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_011117491.1"
                     /translation="MSEQNTFVASDETVGRNRKPNRKAPKQISFRVSESEYLKLQQSAE
                     TLNMSVPAFVKKKAQGARLVAPKLDQATRQSVAKDLSMLGANANQIAKYCNQHQHEAPN
                     YEALERNISELRERLDEIWNMIQK"
                     /name="mobC"
     gene            complement(2760..3560)
                     /locus_tag="SHJJP9001_RS12175"
                     /old_locus_tag="SHJJP9001_002428"
     CDS             complement(2760..3560)
                     /locus_tag="SHJJP9001_RS12175"
                     /old_locus_tag="SHJJP9001_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498218.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_002498218.1"
                     /translation="MKSSLFILKEHFNNLYLMKRLAQFEMKISNKNNYLGTAWELINPS
                     IQIFMYWFIFGLGFRNNRTVENIPFIFWLIVGISMWFFVNQGILNGTKAVTSKYKQVAK
                     MNFPLSILSSYIVLSKFYTHVLLLILIMLICALNGYYPTIYTLQLLIFIPYTLLLTMTI
                     TLLTSTLAVIIRDIQMLMQALMRIIFFISSILYLPTNALVLKVIQFNPIYFIAESYRAA
                     ILYQNWFFITHWKLSLYNLAFLLITFVLGSILHVKYREQFADFL"
                     /name="ABC transporter permease"
     gene            complement(3656..3850)
                     /locus_tag="SHJJP9001_RS12180"
                     /old_locus_tag="SHJJP9001_002429"
     CDS             complement(3656..3850)
                     /locus_tag="SHJJP9001_RS12180"
                     /old_locus_tag="SHJJP9001_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002447414.1"
                     /translation="MKKISKLLIAFSLVTTLSYASASTGFMNDNSHEAFAKSKKKKHKG
                     NGNKHNCFPVGNSEFCTTP"
                     /name="hypothetical protein"
     gene            4584..5189
                     /locus_tag="SHJJP9001_RS12185"
                     /old_locus_tag="SHJJP9001_002430"
     CDS             4584..5189
                     /locus_tag="SHJJP9001_RS12185"
                     /old_locus_tag="SHJJP9001_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002498907.1"
                     /translation="MNKSKVAEIRKQKSLTQENLAEKAYVTVRTIQRMEAGEEVSSETL
                     KSVSNALDVTVNELFESISSSDKEEEIMEISKEQQKQFNYRKNELFTIKLITFSFIFVF
                     LGLFGIFVGELNGLEQNIYRIIWIFALFLSLAIMYYFLNVFISKKLDKKYPMTIGMKNR
                     NRKNEPVKNGWDFMARYWWIVFPIGGFLSWLIPELTGK"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(5237..6094)
                     /locus_tag="SHJJP9001_RS12190"
                     /old_locus_tag="SHJJP9001_002431"
     CDS             complement(5237..6094)
                     /locus_tag="SHJJP9001_RS12190"
                     /old_locus_tag="SHJJP9001_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458658.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_002498908.1"
                     /translation="MSGETVVYKNDMNLVPLRKFNNTEVNLFFTLCNKLKDKGNLTVNV
                     PFEELKELSNYYSHDKKLFIQDLEKFYDKVFSLTYREETENVIRKFILFTKVEIYKDKE
                     YVAIGVNPDLEHIINSLTSNFTKFELKEMTHLKSTYSKHMFRILKQYKHTGYVKIKIDD
                     FRERLDIPNSYRMTNINQKVLAPIIKELGFIFNNLNINKIKAKKGRKIEWLEFTFDAEK
                     RIHNKRQPQMANIDKSRQYISREKTPRWLEERTYEKQIKNEYDPQLEKERKAFLKQLQL
                     DWED"
                     /name="RepB family plasmid replication initiator protein"
     Typing          2396..2634
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.72e-122"
     Typing          complement(5238..6061)
                     /name="rep_cluster_1256"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(866..1881)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.705"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcacactatc ccgacattcg tcgaaacagt ttaattaagg gttcttctca atgctcaata
       61 aattttctcg gcataagcgc atgtgctatt cttcattttc catatctttt acaaccttta
      121 atatcggtgt gattagtaat gataaaataa atgctgattc taaaatcaga aaaatatttg
      181 ttccttcaaa aaatattaag ttgaccacat atccaaaaag acaaaataca ataaaaaaac
      241 aaataaagtg aacaatagaa ttcaaggcga gcactccttt ttggtttcta cgctaattta
      301 agcttgatat agcttcttca ttaaacaaaa ggtaattttc tatttatttt gtattaaaga
      361 cgctcatatg cttttaaaat ggcatatata agcactccaa ataaaatata aggtacaaga
      421 tagaaaacaa gcatgaaata acgccatgct gaatgccccg ttttaagcac gtggttcagc
      481 cattcgtaaa aatgttggac gcctaaccag tcacctaagg gacttataac taaaaaggcg
      541 accatcacta aggcaacgat aaaaaacatg gctgtgatgc ctttagttaa acgatgtatg
      601 acttgatcat attgtttaat cactattgcg ttgctcttca tacgttcatc aatcattttt
      661 ttataattat tattggcttg tcgcagttcg gattggttgt tttgaacttc cttaactacg
      721 ttttgtgtgt ctgttttgac atcttctaat tctttttgta tagctgtgtg aaaatcttgt
      781 tttaaattat cgttattaat ccgttcaata taatgtcttg ccgcgcttat aaaacgcttt
      841 tgtgtgaagt ctgtggcttg attaaagttc gaggccgtgg tctcgatcga tgttaataat
      901 tggtcgtgac gttggtttct ctcgtactct cttttctcga tctcttcgag ccttttcatc
      961 aacaagtctt gctgattctg cagcttgtcg gcgacgctca agctcatttg tgtcttgggc
     1021 gaattggtcc caatctgatt gagtgacgcc tgtatctcgt tcagttgatt catgacggtt
     1081 tgaagttgat cgttttggct ggaagttcgt gtctgattta tgtttttgtt gttgtcgtcg
     1141 ttgtatttgt ctttcaaagc catgttggat gcctccttta ttgtaatctt cgcccaattt
     1201 acgcccgcgt acttttttat tttcagctaa atgccgatag gtaatgcttt tgggggtaac
     1261 acgttcaatc gtaataccat gttgattcag atgtttttga aattcttcca tatttgtcgc
     1321 tgttgattgg tcaattgcct cacgtatgtc atctttccat gagtattgtg ctgtcgacgt
     1381 cgtgttaggg tcggcaatcg ctttttctgt ttgggtgtaa cgtaagcgtg ctgtgtcttt
     1441 ctcaggcacg ctcaacccct gtgctcgaca aacctcgtcg ttgaacgctc tcacatcgcg
     1501 tagggcttgt ttattattgt taaatttctt acctgtattg aggtcaattg aattaagtac
     1561 aatatgattg tgtacatggt ttgtatctgc atgcgtatag acggcgactt gatgattggg
     1621 gacgagtttt tcagcaagcg ctaatcctaa ttggttacat tgttcgggcg tcacttcgcc
     1681 aggttgaaac gattggataa tgacatgccc ttgattaccg tctgttttgc catacaattc
     1741 acgagcggct ttaaaactag atttggcata gtccacgtca caatttaagc cacttttctc
     1801 aacggcacgt ttttcagcgt aattgatggc ccgtgatgtt gatttagtcg cacttaattt
     1861 agttgttgcc attggtatca cgcgcttttt tctttttata tgatatatat aaatcaatac
     1921 ctgtgataaa agttaaaagt gaaaaacaca aaatcaccgg aaattgtgga tcaaagaaaa
     1981 taaaataaaa caatatcatt aaacacatca caaataaaat ggcacttaca atcattttta
     2041 tttttggatc atgttccata tctcatctaa cctttcacgt aattcactaa tgttacgttc
     2101 taatgcttcg tagttcggtg cttcgtgttg atgttggttg caatatttcg caatctgatt
     2161 ggcatttgca cccaacatac ttaaatcttt agctaccgat tgtcgcgttg cttgatccaa
     2221 tttgggtgcg accaatcggg cgccttgtgc ctttttctta acgaacgcag gaacactcat
     2281 atttaaagtt tcagctgatt gttgtaactt taaatattcg gattcgctca cacgaaaact
     2341 aatttgtttc ggcgccttac ggttgggttt acggtttcgc ccaacagttt cgtcgctagc
     2401 cacaaatgtg ttttgttcgc tcattcaatc ccaccacgct ttcttcgaaa gataacgccg
     2461 ttcttacatc ttactttata tgataaagta agattcatca agtcgttaag tggtttggca
     2521 agcattggct ttgctagcca ctaacgtggc agacgcgcct gcttgttggg ggtaatcccc
     2581 aagcccctta tggatttttt ctaacgaaaa aatagtggct aattgctagc cactaaattc
     2641 aaaaccatca aaaccgcagc aaccaaaaat atttttgcta taattattaa acccaaatga
     2701 aaaataaaat taaaaaagaa atgagaataa gatcaaaaat aatgttcttt atattctgtt
     2761 tataaaaaat ctgcaaattg ttcacgatat ttaacatgta aaatagagcc caacacaaaa
     2821 gtaattaaaa ggaaagcaag attatataaa gatagtttcc aatgtgttat aaaaaaccaa
     2881 ttttgatata gaattgctgc tctataactt tcagctataa aatagatagg attaaattgt
     2941 ataaccttta aaactaaagc atttgtcggt aaatataaaa ttgaagatat aaaaaatatt
     3001 attctcataa gagcttgcat aagcatttgg atgtctctaa taattacagc taatgttgaa
     3061 gttaatagtg ttattgtcat tgtcagtaac agagtgtaag ggataaaaat taataattgt
     3121 aatgtatata tagtagggta atatccattt aaagcacata taagcataat taaaataagc
     3181 aataacacat gggtataaaa tttacttaag acgatataac tagataatat agataatgga
     3241 aaattcattt tagctacttg cttatatttg ctagtaactg cttttgtacc atttaaaata
     3301 ccttgattca caaaaaacca catacttatt cctacaatta accaaaaaat aaaaggtata
     3361 ttctcaacag ttctattatt tctgaaacct aaaccaaaaa taaaccaata cataaaaatc
     3421 tgtattgaag gattaattaa ttcccatgct gttcccaaat aattattttt gttagaaatt
     3481 ttcatttcaa attgtgctaa tcttttcatt aaatataaat tattaaaatg ttcttttaat
     3541 ataaacaaag atgatttcat aacattaagt tacctttcta agattatcaa tattataaat
     3601 gaaacctaaa aaaaaggtaa agcaattgtt tattgcttta ccttttctat tttaattatg
     3661 gagttgtaca aaattcactg tttccgactg ggaagcaatt atgtttgtta ccatttcctt
     3721 tatgtttttt ctttttagat ttagcaaatg cttcatgaga gttatcattc ataaaaccag
     3781 ttgaagcact tgcatatgat agtgttgtta ctaatgaaaa tgcaataaga agtttcgaga
     3841 tttttttcat ttctacccct ccaaaatatt aatttaaagt aaagatatca caattttaag
     3901 aaaaatcaag acgaaaaaaa tataaattta ttaattggtt ttagcatata tttttgaaga
     3961 gtaaaatata gaatttttta atattctatt caattttaca aattatacgt attctataca
     4021 aactaactac ctataatagt taattatgtc aacttacaca caagggacaa acgccgtcat
     4081 ttcagcgttt gtccctttta tgtgaattca tggattattc atattttata catcccttta
     4141 acgaagcgtt ttcattcttt ttcatcaagt gaacttttgt atctttattc acaatttcac
     4201 gtgataacac accgttttaa attgtagttt tttgttatac tggaaaagca cttccgtgca
     4261 caaaggaggt gtcacataca atgataatct tgctatttgt actagataag ctcatttttc
     4321 caattattgt tggttatgtt ctttatctat tacaacaaga gcataagtaa aaagaaaccc
     4381 ccagccggca cgctgggggt tttcacatac aatgatatat ctgctatttg ttactttcag
     4441 tatatccttt cttatgcttt ttgtaaaatt agatatatac tttcttttaa gaatataatt
     4501 ttgaagtaac tgtcgtttca ttgtcgccca tctgtcggca atttttcgtg ttcatttttt
     4561 tagttgagga gtagtttatg agtatgaaca aatcaaaagt tgcagaaatt agaaaacaaa
     4621 aatcgttaac tcaagaaaat ttagcagaaa aggcttatgt aacagtaaga acaattcaaa
     4681 gaatggaggc tggagaagaa gttagtagtg aaacacttaa aagtgtctca aacgcattag
     4741 atgtgacagt caatgaacta ttcgaatcta tctcgtcttc tgataaggag gaggaaataa
     4801 tggaaatatc taaagaacaa caaaagcagt ttaattatcg taaaaatgaa ctttttacta
     4861 ttaaattaat aacatttagt tttatttttg tgtttttagg actatttgga atctttgtag
     4921 gtgaattaaa cggtttagaa caaaatattt accgcatcat ttggattttc gctttatttt
     4981 tgagcttagc aataatgtat tattttttaa atgtttttat ttcaaaaaaa ttagataaaa
     5041 aatatcctat gactattgga atgaaaaata gaaatagaaa aaatgaacct gtaaaaaatg
     5101 gctgggattt tatggctaga tattggtgga ttgtttttcc tattggaggg tttctaagtt
     5161 ggctaattcc tgaattaaca ggaaaataaa atacaaaaca aaagatcttt agcaaggggg
     5221 ctaaagatct tttgttttaa tcttcccagt ctaattgaag ttgttttaaa aatgcttttc
     5281 gctctttttc taattgtgga tcatattcat tttttatttg tttttcataa gtacgttctt
     5341 ctaaccatct cggcgttttt tcccgactta tatattgtcg tgacttatct atattcgcca
     5401 tttgtggctg tcgtttattg tgaatgcgtt tctcagcgtc aaaagtaaac tctaaccatt
     5461 caattttacg tccttttttt gcctttattt tattgatatt aaggttatta aaaataaagc
     5521 ctaattcttt aatgataggg gctaatactt tttgattaat atttgtcata cggtaactat
     5581 taggaatatc cagccgttct ctaaaatcat caattttaat ttttacatag ccagtatgtt
     5641 tatactgctt aagtattctg aacatatgct tagaatatgt agatttaagg tgtgtcattt
     5701 ctttaagttc aaatttagtg aagttactag ttaatgaatt aataatatgt tctaaatctg
     5761 gattaacacc aatagccaca tactctttat ctttataaat ttctacttta gtaaaaagaa
     5821 taaattttct aataacattc tcagtttctt ctctatatgt taaagagaaa actttgtcat
     5881 agaatttttc taaatcttga ataaaaagct ttttatcatg actatagtaa ttacttaatt
     5941 cttttaattc ttcaaatggc acattaacag tcaaattgcc tttatctttt aatttattac
     6001 acaaagtaaa aaatagatta acttcagtat tattaaattt tctcagtgga actaaattca
     6061 tatcattttt atatactact gtttctccac tcaactaact ccactccaat ctaaaagaaa
     6121 cctatataga ataaagattc ctattaactt taattgtaaa tacttataat cactatgtta
     6181 taaacaataa taacataaag aaacctaata taaaaaaagt ttctttagtt taatgattgg
     6241 ttgcctttag tttaatgatt ggttgccttt agtttaatga ttggttgcct ttagtttaat
     6301 gattggttgc ctttaacatt tcaaatctat tgtcactcta aggatcaaat gactcctaaa
     6361 aaggttttaa aaagatttat aaaaagatat taaaaagttc ggggcaattt gcccctcaca
     6421 aattcaaaag acaaaaagga aacccaccac atttgtggtg ggtttttatt atttaaaaaa
     6481 gtaataagtg atataacttt aatgcattat tccaattgct ttattgacat tgagcctctg
     6541 aacccttaat aaaccctaaa actgtcgact cgtcggtttc atagc
//
