LOCUS       NZ_CP132628             6925 bp    DNA     circular CON 24-AUG-2023
DEFINITION  Klebsiella pneumoniae strain 15056 plasmid p5, complete sequence.
ACCESSION   NZ_CP132628
VERSION     NZ_CP132628.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36071309
            Assembly: GCF_030845515.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6925)
  AUTHORS   Luo,T.
  TITLE     Differentiation of hypervirulent and classical Klebsiella pneumoniae
            with acquired drug resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6925)
  AUTHORS   Luo,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2023) Walter Reed Army Institute of Research, MRSN
            BI Team, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Trycycler v. 0.5.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 460x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/21/2023 17:33:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,914
            CDSs (total)                      :: 5,789
            Genes (coding)                    :: 5,559
            CDSs (with protein)               :: 5,559
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 230
            CDSs (without protein)            :: 230
            Pseudo Genes (ambiguous residues) :: 0 of 230
            Pseudo Genes (frameshifted)       :: 73 of 230
            Pseudo Genes (incomplete)         :: 162 of 230
            Pseudo Genes (internal stop)      :: 34 of 230
            Pseudo Genes (multiple problems)  :: 35 of 230
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP132628.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="15056"
                     /isolation_source="wound"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p5"
                     /geo_loc_name="Afghanistan:Kabul"
                     /collection_date="2013-02-04"
                     /collected_by="Multidrug Resistance Surveillance Network"
     gene            complement(join(6582..6925,1..802))
                     /locus_tag="RA189_RS29530"
                     /old_locus_tag="RA189_29495"
     CDS             complement(join(6582..6925,1..802))
                     /locus_tag="RA189_RS29530"
                     /old_locus_tag="RA189_29495"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-4"
                     /protein_id="WP_015056382.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAI
                     PGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIK
                     LSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWT
                     PGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYARG
                     YREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWR
                     IGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTG
                     GFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
                     /name="class C beta-lactamase CMY-4"
     gene            complement(1376..2227)
                     /gene="repC"
                     /locus_tag="RA189_RS29535"
                     /old_locus_tag="RA189_29500"
     CDS             complement(1376..2227)
                     /gene="repC"
                     /locus_tag="RA189_RS29535"
                     /old_locus_tag="RA189_29500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_000240536.1"
                     /translation="MVKPKNKHSLSHVRHDPAHCLAPGLFRALKRGERKRSKLDVTYDY
                     GDGKRIEFSGPEPLGADDLRILQGLVAMAGPNGLVLGPEPKTEGGRQLRLFLEPKWEAV
                     TADAMVVKGSYRALAKEIGAEVDSGGALKHIQDCIERLWKVSIIAQNGRKRQGFRLLSE
                     YASDEADGRLYVALNPLIAQAVMGGGQHVRISMDEVRALDSETARLLHQRLCGWIDPGK
                     TGKASIDTLCGYVWPSEASGSTMRKRRQRVREALPELVALGWTVTEFAAGKYDITRPKA
                     AG"
                     /name="repC"
     gene            complement(2214..3053)
                     /locus_tag="RA189_RS29540"
                     /old_locus_tag="RA189_29505"
     CDS             complement(2214..3053)
                     /locus_tag="RA189_RS29540"
                     /old_locus_tag="RA189_29505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_000190708.1"
                     /translation="MATHKPINILEAFAAAPPPLDYVLPNMVAGTVGALVSPGGAGKSM
                     LALQLAAQIAGGPDLLEVGELPTGPVIYLPAEDPPTAIHHRLHALGAHLSAEERQAVAD
                     GLLIQPLIGSLPNIMAPEWFDGLKRAAEGRRLMVLDTLRRFHIEEENASGPMAQVIGRM
                     EAIAADTGCSIVFLHHASKGAAMMGAGDQQQASRGSSVLVDNIRWQSYLSSMTSAEAEE
                     WGVDDDQRRFFVRFGVSKANYGAPFADRWFRRHDGGVLKPAVLERQRKSKGVPRGEA"
                     /name="helicase RepA family protein"
     gene            complement(3083..3289)
                     /gene="urfF"
                     /locus_tag="RA189_RS29545"
                     /old_locus_tag="RA189_29510"
     CDS             complement(3083..3289)
                     /gene="urfF"
                     /locus_tag="RA189_RS29545"
                     /old_locus_tag="RA189_29510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007857788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid repression protein F"
                     /protein_id="WP_007857788.1"
                     /translation="MKDQKDKQTGDLLASPDAVRQARYAERMKAKGMRQRKFWLTDDEY
                     EALRECLEELRAAQGGGSDPASA"
                     /name="urfF"
     gene            complement(3291..3503)
                     /locus_tag="RA189_RS29550"
                     /old_locus_tag="RA189_29515"
     CDS             complement(3291..3503)
                     /locus_tag="RA189_RS29550"
                     /old_locus_tag="RA189_29515"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455501.1"
                     /translation="MEYEKSASGSVYLIKSDKGYWLPGGFGYTSNKAEAGRFSVADMAS
                     LNLDGCTLSLFREDKPFGPGKFLGD"
                     /name="hypothetical protein"
     gene            complement(3564..4535)
                     /locus_tag="RA189_RS29555"
                     /old_locus_tag="RA189_29520"
     CDS             complement(3564..4535)
                     /locus_tag="RA189_RS29555"
                     /old_locus_tag="RA189_29520"
                     /inference="COORDINATES: protein motif:HMM:NF028103.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-primase RepB domain-containing protein"
                     /protein_id="WP_010890158.1"
                     /translation="MKNDRTLQAIGRQLKAMGCERFDIGVRDATTGQMMNREWSAAEVL
                     QNTPWLKRMNAQGNDVYIRPAEQERHGLVLVDDLSEFDLDDMKAEGREPALVVETSPKN
                     YQAWVKVADAAGGELRGQIARTLASEYDADPASADSRHYGRLAGFTNRKDKHTTRAGYQ
                     PWVLLRESKGKTATAGPALVQQAGQQIEQAQRQQEKARRLASLELPERQLSRHRRTALD
                     EYRSEMAGLVKRFGDDLSKCDFIAAQKLASRGRSAEEIGKAMAEASPALAERKPGHEAD
                     YIERTVSKVMGLPSVQLARAELARAPAPRQRGMDRGGPDFSM"
                     /name="DNA-primase RepB domain-containing protein"
     gene            complement(4532..4945)
                     /locus_tag="RA189_RS29560"
                     /old_locus_tag="RA189_29525"
     CDS             complement(4532..4945)
                     /locus_tag="RA189_RS29560"
                     /old_locus_tag="RA189_29525"
                     /inference="COORDINATES: protein motif:HMM:NF036929.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncQ-type mobilization protein MobB"
                     /protein_id="WP_010890157.1"
                     /translation="MNAIDRVKKSRGINELAEQIEPLAQSMATLADEARQVMSQTQQAS
                     EAQAAEWLKAQRQTGAAWVELAKELREVAAEVSSAAQSARSASRGWHWKLWLTVMLASM
                     MPTVVLLIASLLLLDLTPLTTEDGSIWLRLVAR"
                     /name="IncQ-type mobilization protein MobB"
     gene            complement(<5103..5693)
                     /locus_tag="RA189_RS29565"
                     /old_locus_tag="RA189_29530"
                     /pseudo=""
     CDS             complement(<5103..5693)
                     /locus_tag="RA189_RS29565"
                     /old_locus_tag="RA189_29530"
                     /inference="COORDINATES: protein motif:HMM:NF015354.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /name="MobA/MobL family protein"
     gene            5892..6176
                     /locus_tag="RA189_RS29570"
                     /old_locus_tag="RA189_29535"
     CDS             5892..6176
                     /locus_tag="RA189_RS29570"
                     /old_locus_tag="RA189_29535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein C"
                     /protein_id="WP_000238497.1"
                     /translation="MVKGSNKAADRLAKLEEQRARINAEIQRVRAREQQQERKNETRRK
                     VLVGAMILAKVNSSEWPEDRLMAAMDAYLERDHDRALFGLPPRQKDEPG"
                     /name="mobilization protein C"
     ARG             complement(6583..6923)
                     /name="CMY-26"
                     /gene="CMY-26"
                     /gene_name="CMY beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephamycin"
                     /identity="100.0"
                     /coverage="29.66"
     ARG             complement(3..802)
                     /name="CMY-132"
                     /gene="CMY-132"
                     /gene_name="CMY beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephamycin"
                     /identity="99.63"
                     /coverage="70.08"
     Typing          complement(5783..5938)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.28e-76"
     Typing          complement(2215..3036)
                     /name="IncQ1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="96.0"
                     /evalue="0.0"
     Typing          complement(3568..5693)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gcgttttctc ctgaacgtgg ctggcatcca tgttggcctg aacccagcgg gccatatcaa
       61 taacgctgga tttcacgcca taggcttcgg cgtcaagttg tcccggagaa acgtgtacgg
      121 gcttcccttc gcgatagccc ctggcataat ctttttgttc gttctgcgga accgtaatcc
      181 aggtatgcgc cagttttaat ggttgcagga cgcgtctggt cattgcctct tcgtaactca
      241 ttcctgaggg tttcaccgcc agcgcgccaa acagaccaat gctggagtta gcgtaaagtc
      301 gcttagcgcc cggagtccat tgcggctgcc agttttgata aaaatgcagt aatgcggctt
      361 tatccctaac gtcatcgggg atctgcagcg gtaggccgcc tgccgtatag gtggctaagt
      421 gcagcaggcg gataccctgc cactgtttgc ctgtcagttc tggccagtat ttcgtgaccg
      481 gatcgctgag cttaatttcg ccgcgggcga tagcatcgcc gcccaacacg ccgttaaacg
      541 tcttactaac cgatcctagc tcaaacagcg tttgctgcgt gactgggtgg ttattggcga
      601 tatcggcttt accccaggtg aaataatagg gttttccctg gtagataacg gcaacggcca
      661 tacccggaat agcctgctcc tgcatcaacg gggtgatggt gcgattaacg atatcggcaa
      721 tctgttgttc tgtttttgcg gcagcaaatg tggagaaaga ggctgtcagc agcagagcgc
      781 agcataacga ttttttcatc atgaaatcag ttccgtaatt aaaagcaaaa aggtgtccgg
      841 gcccgtcaga cgcaatcagt gtgtttgatt tgcaccgtgt tgacaaacgg ttaaatttag
      901 cagcagatat aagtttttcc taaattccat gtgtgttttt tattagcttc aaaaatcact
      961 atttcacgaa gaatttagac tgcttctcac acattgtaac attatttaca cggagaaact
     1021 gtccgaggtt atgttgacga tgccgaaaat gatgagcgat ttattcatgg gggcttctat
     1081 aataataata atcgagcatg agtctcatac ggatgctcgg gtcgaaaggg aatccccagg
     1141 cgagtaacct gtttgcggtg atccattagc tgcaggagca gaagagcata catctggaag
     1201 caaagccagg aaagcggcct atggagctgt gcggcagcgc tcagtaggca atttttcaaa
     1261 atattgttaa gccttttctg agcatggtat ttttcatggt attaccaatt agcaggaaaa
     1321 taagccattg aatataaaag ataaaaatgt cttgtttaca atagagtggg gggggtcagc
     1381 ctgccgcctt gggccgggtg atgtcgtact tgcccgccgc gaactcggtt accgtccagc
     1441 ccagcgcgac cagctccggc aacgcctcgc gcacccgctg gcggcgcttg cgcatggtcg
     1501 aaccactggc ctctgacggc cagacatagc cgcacaaggt atctatggaa gccttgccgg
     1561 ttttgccggg gtcgatccag ccacacagcc gctggtgcag caggcgggcg gtttcgctgt
     1621 ccagcgcccg cacctcgtcc atgctgatgc gcacatgctg gccgccaccc atgacggcct
     1681 gcgcgatcaa ggggttcagg gccacgtaca ggcgcccgtc cgcctcgtcg ctggcgtact
     1741 ccgacagcag ccgaaacccc tgccgcttgc ggccattctg ggcgatgatg gataccttcc
     1801 aaaggcgctc gatgcagtcc tgtatgtgct tgagcgcccc accactatcg acctctgccc
     1861 cgatttcctt tgccagcgcc cgatagctac ctttgaccac catggcatca gcggtgacgg
     1921 cctcccactt gggttccagg aacagccgga gctgccgtcc gccttcggtc ttgggttccg
     1981 ggccaagcac taggccatta ggcccagcca tggccaccag cccttgcagg atgcgcagat
     2041 catcagcgcc cagcggctcc gggccgctga actcgatccg cttgccgtcg ccgtagtcat
     2101 acgtcacgtc cagcttgctg cgcttgcgct cgccccgctt gagggcacgg aacaggccgg
     2161 gggccagaca gtgcgccggg tcgtgccgga cgtggctgag gctgtgcttg ttcttaggct
     2221 tcaccacggg gcaccccctt gctcttgcgc tgcctctcca gcacggcggg cttgagcacc
     2281 ccgccgtcat gccgcctgaa ccaccgatca gcgaacggtg cgccatagtt ggccttgctc
     2341 acaccgaagc ggacgaagaa ccggcgctgg tcgtcgtcca caccccattc ctcggcctcg
     2401 gcgctggtca tgctcgacag gtaggactgc cagcggatgt tatcgaccag taccgagctg
     2461 ccccggctgg cctgctgctg gtcgcctgcg cccatcatgg ccgcgccctt gctggcatgg
     2521 tgcaggaaca cgatagagca cccggtatcg gcggcgatgg cctccatgcg accgatgacc
     2581 tgggccatgg ggccgctggc gttttcttcc tcgatgtgga accggcgcag cgtgtccagc
     2641 accatcaggc ggcggccctc ggcggcgcgc ttgaggccgt cgaaccactc cggggccatg
     2701 atgttgggca ggctgccgat cagcggctgg atcagcaggc cgtcagccac ggcttgccgt
     2761 tcctcggcgc tgaggtgcgc cccaagggcg tgcaggcggt gatgaatggc ggtgggcggg
     2821 tcttcggcgg gcaggtagat caccgggccg gtgggcagtt cgcccacctc cagcagatcc
     2881 ggcccgcctg caatctgtgc ggccagttgc agggccagca tggatttacc ggcaccaccg
     2941 ggcgacacca gcgccccgac cgtaccggcc accatgttgg gcaaaacgta gtccagcggt
     3001 ggcggcgctg ctgcgaacgc ctccagaata ttgataggct tatgggtagc cattgattgc
     3061 ctcctttgca ggcagttggt ggttaggcgc tggcggggtc actacccccg ccctgcgccg
     3121 ctctgagttc ttccaggcac tcgcgcagcg cctcgtattc gtcgtcggtc agccagaact
     3181 tgcgctgacg catccctttg gccttcatgc gctcggcata tcgcgcttgg cgtacagcgt
     3241 cagggctggc cagcaggtcg ccggtctgct tgtccttttg gtctttcata tcagtcaccg
     3301 agaaacttgc cggggccgaa aggcttgtct tcgcggaaca aggacaaggt gcagccgtca
     3361 aggttaaggc tggccatatc agcgactgaa aagcggccag cctcggcctt gtttgacgta
     3421 taaccaaagc caccgggcaa ccaatagccc ttgtcacttt tgatcaggta gaccgaccct
     3481 gaagcgcttt tttcgtattc cataaaaccc ccttctgtgc gtgagtactc atagtataac
     3541 aggcgtgagt accaacgcaa gcactacatg ctgaaatctg gcccgcccct gtccatgcct
     3601 cgctggcggg gtgccggtgc ccgtgccagc tcggcccgcg caagctggac gctgggcaga
     3661 cccatgacct tgctgacggt gcgctcgatg taatccgctt cgtggccggg cttgcgctct
     3721 gccagcgctg ggctggcctc ggccatggcc ttgccgattt cctcggcact gcggccccgg
     3781 ctggccagct tctgcgcggc gataaagtcg cacttgctga ggtcatcacc gaagcgcttg
     3841 accagcccgg ccatctcgct gcggtactcg tccagcgccg tgcgccggtg gcggctaagc
     3901 tgccgctcgg gcagttcgag gctggccagc ctgcgggcct tctcctgctg ccgctgggcc
     3961 tgctcgatct gctggccagc ctgctgcacc agcgccgggc cagcggtggc ggtcttgccc
     4021 ttggattcac gcagcagcac ccacggctga taaccggcgc gggtggtgtg cttgtccttg
     4081 cggttggtga agcccgccaa gcggccatag tggcggctgt cggcgctggc cgggtcggcg
     4141 tcgtactcgc tggccagcgt ccgggcaatc tgcccccgaa gttcaccgcc tgcggcgtcg
     4201 gccaccttga cccatgcctg atagttcttc gggctggttt ccactaccag ggcaggctcc
     4261 cggccctcgg ctttcatgtc atccaggtca aactcgctga ggtcgtccac cagcaccaga
     4321 ccatgccgct cctgctcggc gggcctgata tacacgtcat tgccctgggc attcatccgc
     4381 ttgagccatg gcgtgttctg gagcacttcg gcggctgacc attcccggtt catcatctgg
     4441 ccggtggtgg cgtccctgac gccgatatcg aagcgctcac agcccatggc cttgagctgt
     4501 cggcctatgg cctgcaaagt cctgtcgttc ttcatcgggc caccaagcgc agccagatcg
     4561 agccgtcctc ggttgtcagt ggcgtcaggt cgagcaagag caacgatgcg atcagcagca
     4621 ccaccgtagg catcatggaa gccagcatca cggttagcca tagcttccag tgccaccccc
     4681 gcgacgcgct ccgggcgctc tgcgcggcgc tgctcacctc ggcggctacc tcccgcaact
     4741 ctttggccag ctccacccat gccgcccctg tctggcgctg ggctttcagc cactccgccg
     4801 cctgcgcctc gctggcctgc tgggtctggc tcatgacctg ccgggcttcg tcggccagtg
     4861 tcgccatgct ctgggccagc ggttcgatct gctccgctaa ctcgttgatg cctctggatt
     4921 tcttcactct gtcgattgcg ttcatggtct attgcctccc ggtattcctg taagtcgatg
     4981 atctgggcgt tggcggtgtc gatgttcagg gccacgtctg cccggtcggt gcggatgccc
     5041 cggccttcca tctccaccac gttcggcccc aggtgaacac cgggcaggcg ctcgatgccc
     5101 tgcgcctcaa gtgttctgtg gtcaatgcgg gcgtcgtggc cagcccgctc taatgcccgg
     5161 ttggcatggt cggcccatgc ctcgcgggtc tgctcaagcc atgccttggg cttgagcgct
     5221 tcggtcttct gtgccccgcc cttctccggg gtcttgccgt tgtaccgctt gaaccactga
     5281 gcggcgggcc gctcgatgcc gtcattgatc cgctcggaga tcatcaggtg gcagtgcggg
     5341 ttctcgccgc caccggcatg gatggccagc gtatacggca ggcgctcggc accggtcagg
     5401 tgctgggcga actcggacgc cagcgccttc tgctggtcga gggtcagctc gaccggcagg
     5461 gcaaattcga cctccttgaa cagccgccca ttggcgcgtt catacaggtc ggcagcatcc
     5521 cagtagtcgg cgggccgctc gacgaactcc ggcatgtgcc cggattcggc gtgcaagact
     5581 tcatccatgt cgcgggcata cttgccttcg cgctggatgt agtcggcctt ggccctggcc
     5641 gattggccgc ccgacctgct gccggttttc gccgtaaggt gataaatcgc catgctgcct
     5701 cgctgttgct tttgcttttc ggctccatgc aatggccctc ggagagcgca ccgcccgaag
     5761 ggtggccgtt aggccagttt ctcgaagaga aaccggtaag tgcgccctcc cctacaaagt
     5821 agggtcggga ttgccgccgc tgtgcctcca tgatagccta cgagacagca cattaacaat
     5881 ggggtgtcaa gatggttaag gggagcaaca aggcggcgga tcggctggcc aagctcgaag
     5941 aacaacgagc gcgaatcaat gccgaaattc agcgggtgcg ggcaagggaa cagcagcaag
     6001 agcgcaagaa cgaaacaagg cgcaaggtgc tggtgggggc catgattttg gccaaggtga
     6061 acagcagcga gtggccggag gatcggctca tggcggcaat ggatgcgtac cttgaacgcg
     6121 accacgaccg cgccttgttc ggtctgccgc cacgccagaa ggatgagccg ggctgaatga
     6181 tcgaccgaga caggccctgc ggggctgcac acgcgccccc acccttcggg tagggggaaa
     6241 ggccgctaaa gcggctaaaa gcgctccagc gtatttctgc ggggtttggt gtggggttta
     6301 gcgggctttg cccgcctttc cccctgccgc gcagcggtgg ggcggtgtgt agcctagcgc
     6361 agcgaataga ccagctatcc ggcctctggc cgggcatatt gggcaagggc agcagcgccc
     6421 cacaagggcg ctgataaccg cgcctagtgg attattctta gataatcatg gatggatttt
     6481 tccaacaccc cgccagcccc cgcccctgct gggtttgcag gtttgggggc gtgacagtta
     6541 ttgcaggggt tcgtgacagt tattgcaggg gggcgtgaca gttattgcag cttttcaaga
     6601 atgcgccagg ccgcctcgac acggacaggg ttaggatagc ttttgtttgc cagcatcacg
     6661 atgccaaggt ttttttctgg aacgaaggct acgtagctgc caaatccacc agtggagccc
     6721 gttttatgca cccatgaggc tttcactgcg ggggcgggcg ggtttacctc aacggcggga
     6781 agcgctgcca atgccacttt gctgtcgctg ccgttgatga tcgaatcagc tttcagcggc
     6841 cagttcagca tctcccagcc taatccctgg tacatatcgc caatacgcca gtagcgagac
     6901 tgcgcaagcg caatgccctg ctgga
//
