LOCUS       NZ_CP132287            11203 bp    DNA     circular CON 26-JAN-2024
DEFINITION  Citrobacter youngae strain UL-CPE-01 plasmid pUL-CPE-08, complete
            sequence.
ACCESSION   NZ_CP132287
VERSION     NZ_CP132287.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN13927060
            Assembly: GCF_010119415.2
KEYWORDS    RefSeq.
SOURCE      Citrobacter youngae
  ORGANISM  Citrobacter youngae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 11203)
  AUTHORS   Ryan,M.P., Pembroke,J.T. and Slattery,S.
  TITLE     Characterization of an Extensively-Resistant Citrobacter youngae
            isolate carrying blaKPC-2 from municipal wastewater
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11203)
  AUTHORS   Ryan,M.P., Pembroke,J.T. and Slattery,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2023) Department of Chemical Sciences, University
            of Limerick, University of Limerick, Limerick, Limerick 00000,
            Ireland
REFERENCE   3  (bases 1 to 11203)
  AUTHORS   Ryan,M.P., Pembroke,J.T. and Slattery,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JAN-2020) Department of Chemical Sciences, University
            of Limerick, Limerick, Ireland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-APR-2023
            Assembly Method                   :: SPAdes v. 3.15.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30.0x
            Sequencing Technology :: Oxford Nanopore PromethION; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/25/2023 15:07:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,015
            CDSs (total)                      :: 5,896
            Genes (coding)                    :: 5,747
            CDSs (with protein)               :: 5,747
            Genes (RNA)                       :: 119
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 45 of 149
            Pseudo Genes (incomplete)         :: 112 of 149
            Pseudo Genes (internal stop)      :: 22 of 149
            Pseudo Genes (multiple problems)  :: 28 of 149
            Pseudo Genes (short protein)      :: 1 of 149
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP132287.1.
            Bacteria and source DNA available from Michael Ryan.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11203
                     /organism="Citrobacter youngae"
                     /mol_type="genomic DNA"
                     /strain="UL-CPE-01"
                     /isolation_source="sewage sludge"
                     /db_xref="taxon:133448"
                     /plasmid="pUL-CPE-08"
                     /geo_loc_name="Ireland"
                     /collection_date="2017-11"
     gene            complement(join(11107..11203,1..152))
                     /locus_tag="GXN37_RS30010"
     CDS             complement(join(11107..11203,1..152))
                     /locus_tag="GXN37_RS30010"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743609.1"
                     /translation="MASPTEAVHRARAQSIQDAAFLNEMKAAGVAPADLVLLDGVLTSS
                     RGMPDAARAPAFAEVRRQVQAGGMTLSPAARGIDWNA"
                     /name="hypothetical protein"
     gene            complement(314..973)
                     /locus_tag="GXN37_RS30015"
     CDS             complement(314..973)
                     /locus_tag="GXN37_RS30015"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061548402.1"
                     /translation="MTEIKKESADGAWLRSTLAELAGDAFPVYDLPSLQVDTNSSIQLS
                     ALADRQAAREMRQAASDVEARRLDAARVVEGLKTEAERLRGLIADGKAALRAGEPVSPD
                     AGVASFLLPDIEAELVVAEAAEADVARERDTLLQDADRRDAAAALALFNWAHSVRVQRI
                     ELLLKLAMDEATTLAETDGGRGLYRTVIAPDRRLNQIFATQGAIEILRRNRGMEGV"
                     /name="hypothetical protein"
     gene            1224..1799
                     /locus_tag="GXN37_RS30020"
     CDS             1224..1799
                     /locus_tag="GXN37_RS30020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016151785.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_101998997.1"
                     /translation="MSRVFGYGRVSTGEQTVAGQKKAILDRYPQATFHADEGISGTVPA
                     TQRDKFKAILEFAAPGDSIVVVAIDRIGRNARSVMEVCEELEKRQVSLISLREGFDFST
                     PTGKMMLTMVAAFAEMELATLKERTKAGMAAAAAAGRHAGRPTKQTPENVGAVIMKHDA
                     GVSAARIARDLGISRGTVNRILQKHAKA"
                     /name="recombinase family protein"
     gene            2027..2239
                     /locus_tag="GXN37_RS30025"
     CDS             2027..2239
                     /locus_tag="GXN37_RS30025"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743611.1"
                     /translation="MTYRLSPRLKALARWTKLANNGARWALLNTRDEVVAWGRYLSDYT
                     LCSASRRTDVRLVNVAEEIDRLIES"
                     /name="hypothetical protein"
     gene            2474..2941
                     /locus_tag="GXN37_RS30030"
     CDS             2474..2941
                     /locus_tag="GXN37_RS30030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324036.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_172743613.1"
                     /translation="MKKYTPEQKAQALKLLEQDGATSASVARTMGIPASTVRGWASEKA
                     AAPSNVLSIEEMRERAQRAVEATPTAKLLRLKNHFTEKQYELLNRHATDLQALRNKALQ
                     ATIQGDAVMMKATASLIAVMIHAQKHEREIYNIKPGTEHEILKLGMNRQQS"
                     /name="transposase"
     gene            complement(3596..5167)
                     /locus_tag="GXN37_RS30035"
     CDS             complement(3596..5167)
                     /locus_tag="GXN37_RS30035"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743615.1"
                     /translation="MSNHEENSGAAVATVTPITAAPSPLSLKLGDALFSVLSVSADWSG
                     DYRAQFELYGLNVKAINSAVGTAVWHAGKGRFLSVLNGSLTEFDKGDGMKLLEDSCGKF
                     WHRTDAFIARLTDLKIKTDDKVTKACIDMARAVRQAVAEFIMLRRQVAVVRLDVDMFAT
                     APRVELVGETVTFVRPHAPYPVANADSDVVADWLVHFPQCHEFLDALVAARFASSRKNA
                     YLFFRAQSDWGKGLLFGAGGVLSRLGATVELSEGELLNILSGANSGVTASHFMGALALI
                     VNECTRVTKKHFRLEESLALTPKYLTTQCVNLYMKIFTSADPIPGLSDTNGIDPQVANR
                     FSMLDLQGDIKTRPLFLSDKGRYVDSLTSFFAAELNARVASYQAKGFDAARRDADHVLA
                     AFTAAHGLAKTAGLITDAYDEIRDDWVAFVHSRVADGHPDFLTFESSNGLVLRSPAGCW
                     SRFLEWYVDKSEPLRRARLLHDRDLIIGVAKAERDVTTGKVTKGVILPFVSGSMPDNVH
                     RFRYKN"
                     /name="hypothetical protein"
     gene            5678..6166
                     /locus_tag="GXN37_RS30040"
     CDS             5678..6166
                     /locus_tag="GXN37_RS30040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743617.1"
                     /translation="MREKTRTLTVRLPVSLIERIEQRAEKTKVTRTDAVIEALVAGLGT
                     KPEGMDTKLLTAIEALRSEVRALAGGGKDARQFAPQTARQSAPQNARQIVPRGADPRFQ
                     AVSDEADQLIVSMTGENATLPAIAQALNAAGHTTATGQEWNTSRVRDYRHKLRERGLI"
                     /name="hypothetical protein"
     gene            complement(6184..6645)
                     /locus_tag="GXN37_RS30045"
     CDS             complement(6184..6645)
                     /locus_tag="GXN37_RS30045"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061301015.1"
                     /translation="MKSKTELRAAATARALEVIASEMGAWSADDFNVQMLPNFSAGERR
                     ETVAGSVVIERPPFDYEWAGTEKFNALATRALQVKLPASRERNYAWLCGVERETLATAL
                     LVELFSVTGCVEFAGLGKVADLAFLTLDEDDAGQIRAAMVGWLDDPAAA"
                     /name="hypothetical protein"
     gene            complement(6903..8075)
                     /locus_tag="GXN37_RS30050"
     CDS             complement(6903..8075)
                     /locus_tag="GXN37_RS30050"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743605.1"
                     /translation="MAFVDFDTTHLKEDPGLFWRAVSAAGAPADRDEWVRLCLALGCWA
                     SLCGEDGLAAIEAWSTRHGRGENRHRQQYRSFLKGDLDTFAAQAFLNFSGVEWRNGRAS
                     VQSDVDRAERLRLSREATAKAKAERDKKGDAAARAAVKLLAKGGDPASTPYWRKKTALA
                     AAGGVQLPALSTDLGVGGMFRSFDPRAYWSDCLLIPVYKFDAARQLYVDGLEAICGRCS
                     AEGSQLTGSKFSPAGTRKQGGFYPMPGFMDVLDGSPHAPYSPLFVCEGFATAFALHHLS
                     RGKVAVCAAFSIAGFGSCVASLRRFWPDVEVMLVPDAGEAYRLAHKAAYGDDREPVPTI
                     PGASVVSFDGLNRFEPRDNLDWFDVLVEEGEDRARELLRYAVRHARLERG"
                     /name="hypothetical protein"
     gene            complement(8062..8271)
                     /locus_tag="GXN37_RS30055"
     CDS             complement(8062..8271)
                     /locus_tag="GXN37_RS30055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_064186834.1"
                     /translation="MKKRIYTADLAALLNVSLRTLSRLSSRGIVPTPAGRSLRGGHYWL
                     AGNPEIKRFVADQRRPGRAADGVR"
                     /name="hypothetical protein"
     gene            8627..9916
                     /locus_tag="GXN37_RS30060"
     CDS             8627..9916
                     /locus_tag="GXN37_RS30060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_172743607.1"
                     /translation="MNDDNDTNESTQPNPAALERVSATEKFPEQLPGVLFVTCPGGCSL
                     RVEACRQIYEQSHLDRTIENPHLECHRCPTGLALWVGTEQPPDAPLTTPADTRKLCPRC
                     SRKDNRLIAPNKPGSSLCVSCWNREREATIGANARGRVNRTPPFVSPFLIGIGDGWQVW
                     YGIHQGEALVRAMRANPGARFHDRRPGPVGQTRRDGFVYYCHEHREPLRWNGGDGHAGE
                     VELACPRCQPWAAPLSVAPTFQTVSFQTPHDAAHQYRNATLPDNAVWTASVCSDCKAAP
                     LVISKAPVKGKPRREIVVSCPSCDSSASARPGGRTWTDEHIAVPEFTQNETRSLAKIPV
                     ILPQREQPQLLKRPGTGRGPGRPRKRIPLTLDRVPESRFNRLTLSVLAAVGRWDYINDI
                     IRRIDRDRGDAATLIALADHIRTNRPERDL"
                     /name="hypothetical protein"
     gene            9913..10554
                     /locus_tag="GXN37_RS30065"
     CDS             9913..10554
                     /locus_tag="GXN37_RS30065"
                     /inference="COORDINATES: protein motif:HMM:NF016255.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_145062807.1"
                     /translation="MTEPTRPILTIKRRNRTVYVPPEKATKSEPQPAERTTSKAKVQPK
                     AKAPQKPAQKPTAAKPKKTPEQVAEGIRRQEENDRRQQDIAIANKSKKALANRVTKAFL
                     KEHWPDLLTRGVDRRPMAKGIIEQILTRGAELDMPPEADRKAVRRILGIVTGTSSYQQS
                     LIDQCMRYDLDGNPTEPATPEEAENAKARLTEIKAFRRKARQAKGEKKGA"
                     /name="ProQ/FINO family protein"
     gene            complement(10574..10759)
                     /locus_tag="GXN37_RS30070"
     CDS             complement(10574..10759)
                     /locus_tag="GXN37_RS30070"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162780107.1"
                     /translation="MSEFAVSRLVIPEVVIPDGVIAARRARGQAQRVAAARRAAERRAA
                     PTWRWVRREQPRSTGR"
                     /name="hypothetical protein"
     gene            complement(10752..11114)
                     /locus_tag="GXN37_RS30075"
     CDS             complement(10752..11114)
                     /locus_tag="GXN37_RS30075"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_064186829.1"
                     /translation="MRKLPRHLQGEVLMPLSSRITRSQRLELIWLLPVLRLHPGDRSVT
                     ERRALGRFRGSLAAGGQTDAFVRSDASLYALGLRFQRKRTRELVASDPDVAAAGEALEQ
                     RANGVNLSETFGGGDE"
                     /name="hypothetical protein"
ORIGIN
        1 gcgtctggca taccgcgaga ggacgtcagc acgccgtcga gcagcaccag gtcagccggt
       61 gccacacccg ccgccttcat ctcgttcaga aacgccgcgt cctggatgga ctgcgctcgc
      121 gcccggtgaa ccgcctcggt cggagacgcc accggagccc cgatcggcgc gaaagtctgc
      181 gcagcgccgc ctgtctccac cactgtctcg accactgacg acagcggagg gaggccgaag
      241 tcatcagcgc cggtggattt ggtcagcgtc gcctcattac gaagccggtc acacaggagt
      301 ttgaaagcag acattacaca ccctccatgc cacggttacg gcgcaggatt tcaatagcgc
      361 cctgcgtggc gaaaatttgg ttaagacggc ggtcaggcgc gatcacggta cggtacaggc
      421 cgcgcccgcc gtcggtttca gcgagcgtcg tcgcctcgtc catcgccagc ttgagaagca
      481 gctcgatacg ctgcacgcga acggagtgcg cccagttgaa cagcgccagc gcagccgccg
      541 cgtcacggcg atcggcatcc tgcagcaggg tgtcacgctc ccgggccacg tcggcctcag
      601 cagcctcagc aacaaccagc tcggcctcga tgtccggcag caggaacgac gcaacacccg
      661 cgtcggggct caccggctcg ccagcacgca gcgcagcctt gccgtcggcg atcaaacccc
      721 gcagccgttc ggcctcggtc ttgagccctt ccaccactcg agcggcgtcc agccgtcgcg
      781 cttccacgtc ggaagcggcc tgtcgcattt cacgcgcagc ctgacgatcg gcgagcgccg
      841 agagctgaat ggaggagttc gtgtctacct gcagggacgg gaggtcatac acagggaacg
      901 catcacccgc caattcggca agggtagagc gtagccaagc gccgtcggcg ctctctttct
      961 taatttcggt catggtttgg ttctcagcaa gttatcagca aagcggcaag aaacgccgct
     1021 cagacagcat gccgtcacga cgcagcgcag acatcaacgc agagggcgca gggctctcgc
     1081 ccagcgcggg gtgatcacgt ccaaaaagga gcgaaactgc gcagcccccg tggctctagg
     1141 cgtttacagt tttttgcgct tgctttttgc tcataagtgg tcaaatatcc ccaaacaacc
     1201 ttttttgtac aacaggagac agcatgagca gagtattcgg gtacgggcgc gtcagcaccg
     1261 gagaacagac agtagccgga cagaagaaag cgatcctcga tcgctaccca caagccacct
     1321 tccacgccga cgagggcatc agcggaacgg tacccgccac ccagcgcgac aagttcaaag
     1381 ccatcctgga gtttgccgca ccaggcgaca gcatcgtggt ggtcgcgatc gaccgcatcg
     1441 gacgcaacgc cagatcggtc atggaggtct gcgaggagct ggagaagcgg caggtcagcc
     1501 tgatcagcct ccgcgaaggt ttcgacttca gcaccccgac cgggaagatg atgctcacca
     1561 tggtcgctgc cttcgcagag atggaactcg ccaccctcaa ggagcgcaca aaggcaggga
     1621 tggcagcagc cgcagccgca ggacgccacg caggacgacc gaccaaacag acgccggaga
     1681 acgtcggagc ggtgatcatg aagcacgacg caggagtaag cgccgcacgc atagcacgcg
     1741 acctaggcat cagcagggga acggtgaaca gaattttaca gaagcacgcg aaagcgtaag
     1801 agagagcgca gcggtgcagg tggatccaac cattccgcac cgccgcaacc cagcccgggg
     1861 aacgcatgag gagcagaccc gggcacgtta acccacccaa atgaggtaac accatgatcg
     1921 tatcaccaca gagcatcgca cgccagctgg cacgccgcgc agtcaccaac cgcaacccgc
     1981 agacatggcg cagagccatg cgccgccttc gccgcgaggt agcagcatga cctaccgcct
     2041 aagcccacgc ctcaaggcgc tggcacgctg gacgaagctg gcgaacaacg gcgcacgatg
     2101 ggcgctcctc aacacccgcg acgaagtggt cgcatggggc aggtacctca gcgattacac
     2161 cctttgcagc gccagccgcc gcaccgacgt caggctggtc aacgtcgccg aggagatcga
     2221 ccgcctcatt gaaagttaag cgccgcttac accgtaggcg attcttactt acaccatagg
     2281 caatacttac acacggggcg gggagccgcc ccaaccaacc agaagccctc agacgcactg
     2341 taagccactc agccacgaaa ccgcaccgac gtaccaacca gcacgcgatc gccactccta
     2401 ccccccaaaa gttgccgcca ttctcagcgc gtgacgctca aatagccgga gggaaccaac
     2461 cggagcagga accatgaaga aatacacccc cgaacagaaa gcccaggcac tcaaactact
     2521 ggagcaggac ggcgcaacca gcgccagcgt cgcacgcacc atggggatcc ccgccagcac
     2581 cgtcagagga tgggcaagcg agaaggccgc agcacccagc aacgtcctca gcatcgagga
     2641 gatgcgagaa cgcgcacagc gagccgtcga ggccaccccc acagccaagc tcctgcgcct
     2701 gaagaaccac ttcaccgaga agcagtacga gctactcaac agacacgcca ccgacctgca
     2761 agccctacgc aacaaggcgc tacaggccac cattcagggc gacgcggtca tgatgaaagc
     2821 caccgccagc ctcatcgccg tcatgatcca cgcgcagaag cacgagcggg agatctacaa
     2881 catcaagcca ggcaccgagc acgagatcct caagctcggc atgaaccgtc agcagagctg
     2941 aaaacgacgg gaaaaccgcc tttttaccgt cactgttccg tcagcaaaaa cccgccagcc
     3001 cccggaatac gcggatccgc acgttacgca attgttaccg ctcgcgtgcg cgagaagccc
     3061 cgttttgatg cccggacgaa ccaaacgcgc acctgcagct acgcattcca ctcataacgc
     3121 agagggcgcg agggcacgcc ctcacgctga accaccaagc gaccacccag cgcgagcgac
     3181 agctcgtgcc ctcagcgacc ccccaaccac cccctaacca ctaccaccca ccaccccggc
     3241 acgacgaacc tatccaccga tcgaccaaga caagcaaagt gcatccccga aggggtgcag
     3301 ctgcggcgcg tcaactgcgc aggaattgag ctgtaaccgc ctgtaaccgc ctgtaaccaa
     3361 tactgtaacc gcaaaaaagc ctttaaaatc aacaatgcaa ccttgtaacc attaaaacag
     3421 aaagacttat tagaaaaaaa tagaaaacag ttttcatagc agggatcgtt cggtattttc
     3481 cggttacaaa gttgcagcca gagctggcac gggtttgcgg cggttacaag gtcggttaca
     3541 gacggttgca agccggttac aaggcgtaaa aaaacccgcc gaagcgggtt attgtttaat
     3601 ttttgtacct gaaccggtga acgttgtcag gcatcgaacc ggaaacgaag gggaggatca
     3661 cccccttggt cactttgccg gtggttacat ccctttcagc ctttgccacc ccaatgatca
     3721 ggtcgcggtc atgcagcagg cgagcacggc gcagtggttc gcttttgtcc acgtaccact
     3781 cgaggaaccg actccagcat ccagcaggtg agcggagaac gagcccgtta gacgactcga
     3841 aggtgaggaa gtcagggtgc ccatcggcaa cacggctatg aacgaacgca acccagtcgt
     3901 cgcggatttc gtcatacgca tcggtgatca gcccggcggt tttcgctaac ccatgcgcgg
     3961 cggtgaaagc agccagaaca tggtcagcat cgcggcgggc ggcatcaaag cccttcgcct
     4021 gataggacgc cacccgagca tttagctcgg cggcaaagaa cgacgtcagg ctgtcgacat
     4081 agcgtccctt gtcggacagg aacagcgggc gcgtcttgat gtcgccctgc agatcgagca
     4141 tagaaaaacg gttggccacc tgcgggtcaa tgccattggt atcggacagg ccggggattg
     4201 gatcggcgct ggtgaaaatt ttcatgtaca ggttcacgca ctgcgtcgtg aggtacttcg
     4261 gcgtcagagc cagcgactcc tcaagacgaa agtgcttttt cgtcaccctg gtgcattcgt
     4321 tgacgatcag cgccagcgcc cccatgaagt gactagccgt tacaccggag ttggcaccgc
     4381 tcaggatgtt gagcagctcc ccctcggaca gctccaccgt cgcccccagg cgtgacagaa
     4441 cgccgccagc accaaacagc agccccttac cccaatcgga ctgcgcacgg aaaaacaggt
     4501 aggcattctt acggcttgaa gcaaagcggg ctgcaaccag cgcgtcgagg aactcatggc
     4561 attgagggaa atgaaccagc caatcagcca ccacgtcact gtcggcatta gccaccggat
     4621 agggagcatg aggacggacg aacgtcacag tttcacccac cagttcgacg cgaggagccg
     4681 tggcgaacat gtccacgtcg aggcgaacga ctgccacctg acggcgcagc atgatgaact
     4741 cagccaccgc ctgacgaaca gcccgagcca tatcgataca cgccttggtt accttgtcgt
     4801 cggtcttgat tttgaggtca gtcaggcggg cgataaacgc atcggtgcgg tgccagaact
     4861 tgccgcagga gtcctccagc agcttcattc cgtcgccctt atcgaactcg gtcagggagc
     4921 catttaggac agagaggaac cgccccttgc cagcgtgcca gacggcagtg ccgacggcag
     4981 agttgatagc ttttacattc aggccataca gctcgaattg agcgcggtag tcaccagacc
     5041 agtccgcaga caccgacaag acagaaaaca gcgcatcgcc caattttagc gacagcggtg
     5101 acggtgcggc ggtgatcggc gttacggtgg cgacagcagc gccagaattt tcttcatggt
     5161 ttgacaattt tacgtcctca aaattgaaca gccaatctca aggagcctta caacggcggg
     5221 actttacgag gaaaacaccc tttgcacgcg tcattatgat cgcgtataat tcacgctggc
     5281 ttcacaccca acatgagtta ttatgtgttt tccacggtgc ccgccgtgaa agctccaaac
     5341 tcaaaacagc tttgaagaaa acccgtctcc ccaaggcggg tttttctttt tcagccgcgc
     5401 catcataccg ttacacccac cccctgcgcc agtacatagc gatcccgcag cgataaacgc
     5461 gatcccgcgc cgatcttaga gccgcgcagc ctccgcgact tatccacggg ccggaaagtc
     5521 cgaaattttg ttatccacag aagttatcca cgggccgcgc cgctacccct tcctgcacga
     5581 caattgcact acgtcaaatt cgacgcgcac gacaaaacgc attacactcc gcaagacaaa
     5641 cagcacgaca aaacgcacga cacggagagg ccagcccatg cgagagaaaa ccagaaccct
     5701 aaccgttcga ctgcccgtca gcctgatcga gcgcatcgag cagcgagcgg agaaaaccaa
     5761 agtaactcgc acagatgccg taatagaggc gctcgtcgcc ggactcggca cgaagccgga
     5821 agggatggac accaaacttt tgaccgccat cgaggcgctg cggtcagagg tcagggcgct
     5881 ggccggaggc gggaaagatg cacgacagtt tgcaccacaa acagcacgac aaagcgcacc
     5941 acaaaacgca cgacagatag tcccccgggg agccgatccc cgcttccagg ccgtcagcga
     6001 tgaggccgac cagctcatcg tcagcatgac cggggagaac gccaccctgc ccgcgatcgc
     6061 ccaggcgctg aacgcagccg ggcacaccac cgccaccggg caggagtgga ataccagccg
     6121 cgtccgggac taccgccaca agctgcgcga gcgcggcctg atttgacgca gaggggcgac
     6181 ggctcacgcc gccgccgggt catccagcca gccaaccatc gccgcccgga tctgccctgc
     6241 atcgtcctcg tccagcgtca ggaacgccag atcggcaacc ttacccagcc cggcgaactc
     6301 cacgcagccg gtgacggaga acagctccac caggagcgcc gtcgccaacg tctcccgttc
     6361 caccccgcac aaccaggcgt agttacgctc acgcgacgcc ggaagtttca cctgcagcgc
     6421 acgggtggcc agcgcgttaa atttctcggt acccgcccac tcgtagtcga acggggggcg
     6481 ctcgatcacc accgagcccg ccaccgtctc gcgacgttcc cctgcggaga agttcggcag
     6541 catctggacg ttgaagtcgt ccgcagacca cgcccccatc tcagaagcga tcacctcaag
     6601 ggcgcgagcc gtcgcggcag cgcgtaattc agtctttgat ttcatgagcc ctccttacgg
     6661 gcgaaaaaaa aacccgacac caaaacggtg ccgggcttga gtgtgctgct ggaaaccaaa
     6721 ccagctgcag gatagcgtca cgaccgcagc ggcgtctaaa acggaggaaa ccggaagcgg
     6781 tcggatgtgc gtcttaaagg ttgtctcacc aacccaaaag cgactgcaaa aaagacgagc
     6841 cagaaaacga ccctttacgg tcagcggcct cccgaggaaa ccgacgcaaa aaagcccagc
     6901 catcagcccc gctcaagccg ggcatgacgc accgcatacc ggagcaactc acgcgcccga
     6961 tcctcgccct cctcaaccag cacgtcgaac cagtcgaggt tatcgcgggg ctcgaagcgg
     7021 ttcaggccgt cgaacgacac caccgacgca cctggaattg tcgggaccgg ttcgcgatcg
     7081 tcgccatagg ccgctttatg cgccagccgg tacgcctctc ccgcgtccgg tacaagcatc
     7141 acctcaacat caggccagaa ccgacgcagc gacgccacgc agctgccgaa cccggcgatc
     7201 gagaacgcag cgcagaccgc caccttgcca cggctcaggt ggtgcagggc gaacgccgta
     7261 gcgaacccct cacagacgaa cagaggcgag tagggcgcgt gcggggagcc gtcgagcacg
     7321 tccatgaacc ccggcatcgg gtagaagccg ccctgcttgc gggtacccgc cggagagaac
     7381 ttcgagccag tgagctggga accctcagcc gagcagcgcc cgcagatggc ctccaggccg
     7441 tcaacataca gctgacgggc ggcgtcgaac ttgtaaaccg gaatcaggag gcaatcagac
     7501 cagtaagcac gcggatcgaa cgatcgaaac atcccgccaa caccaagatc tgtgctgagg
     7561 gcgggcagct ggacgccacc cgcagccgcc agagcggtct ttttgcgcca gtatggggta
     7621 gacgcaggat cccctccctt cgccagcagc ttgaccgcag cacgcgcagc agcatcaccc
     7681 ttcttgtcgc gttcagcctt tgccttcgct gtggcctcac gggacaaccg cagccgttca
     7741 gcgcgatcga cgtcggactg gacagaagcg cgaccgttgc gccattcgac gccggagaaa
     7801 ttgaggaaag cctgagcggc gaatgtatcc aggtcgcctt ttaaaaacga cctgtactgc
     7861 tggcgatggc gattctcgcc tcgcccatgt cgagtggacc aggcctcgat agctgccagc
     7921 ccgtcctcgc cgcagagaga cgcccagcaa ccaagagcca ggcagagacg cacccattcg
     7981 tctcgatcag ccggagcacc cgcagccgat acggcacgcc agaacaggcc cggatcctct
     8041 ttcagatggg tagtgtcgaa atcaacgaac gccatcagca gccctccccg gacgacgctg
     8101 gtcggcaacg aagcgtttga tctcgggatt gccagccagc cagtaatgcc cgccacggag
     8161 ggagcgccct gccggagtcg gcacgatccc ccgcgaactt agccgcgaga gcgtgcgcag
     8221 cgacacgttc agcagcgcag cgaggtcagc ggtatagatt cgttttttca ttgggagtac
     8281 cagataggtg cccccctcag cttaacgggc atcggggggc gggagtgacg attatcgata
     8341 aagccgccct tgaggactta ccgcatagcg gcaggacagc agcccttctc gcttactcgc
     8401 acctgccaag gacgaagcgc gcatcctcgt ttacaacccc gcctcgttgg ggaggaggga
     8461 aagcggcacc gggcgatccg gtttcatgtt tcccaactgc tcgtcaggaa tcagtaagac
     8521 aagcgtaaca caattaacgc caaagtggcg ttttttgtga gatactaaaa aagacgcaca
     8581 gccagtgctg gcgctgtctg gcgaccattt cgacgcaggg ggagcagtga acgacgataa
     8641 cgacacgaac gaatcgacgc agccgaaccc ggcagcactt gaacgcgtaa gcgcgactga
     8701 aaaattcccc gagcagctcc ccggcgtttt gttcgtcacc tgccccggcg ggtgctccct
     8761 ccgggtcgag gcatgccgac agatttatga gcagagccac ctcgatcgca cgattgaaaa
     8821 cccccacctc gagtgccacc ggtgccccac tggcctcgcg ctttgggtcg gtaccgaaca
     8881 gccccctgac gcaccactga ccaccccggc agacacccgt aagctctgcc cccgttgcag
     8941 ccggaaagac aaccgcctga tcgcccccaa taagcccggt tcgagcctgt gcgtctcctg
     9001 ctggaaccgc gaacgcgaag ccaccatcgg agccaacgca cgcgggagag tcaaccgcac
     9061 cccaccgttc gtctcgccgt tcctgatcgg catcggcgat ggctggcagg tctggtacgg
     9121 catccaccag ggcgaggcgc tcgtccgcgc catgcgagcc aacccgggcg cacggttcca
     9181 cgatcgccga ccaggcccgg tcgggcaaac acgccgcgac ggtttcgtgt actactgcca
     9241 cgaacaccgc gagcccctgc gctggaacgg tggcgacggg cacgccggag aggtggagct
     9301 tgcttgtccc aggtgccagc catgggcggc acccctcagc gtcgccccca cgtttcagac
     9361 ggtcagcttc cagacaccgc atgacgccgc gcaccagtac cggaacgcca ccctgccaga
     9421 caacgcggtc tggacagcgt cggtctgctc cgattgcaaa gccgcgcccc tggtgatcag
     9481 caaggcaccg gtcaagggca agccgcgacg ggagatcgtc gtctcctgcc cgtcctgcga
     9541 ctccagcgca tcagccaggc ccggaggcag gacatggaca gacgagcaca tcgcggtgcc
     9601 cgagttcacg cagaacgaga cgcgcagcct ggcgaagatc cccgttattt tgccgcagag
     9661 ggagcagccg cagctgctca aaagaccagg gacagggcgc ggtccaggac gcccccgcaa
     9721 gcgcatcccc ctgaccctcg accgggtacc agagagtcgg ttcaaccgcc tcaccctttc
     9781 cgtccttgcc gccgtcgggc gctgggacta catcaacgac atcatccggc gcatcgatcg
     9841 ggaccgcggc gacgccgcca ccctgatcgc ccttgccgac cacatccgga ccaacagacc
     9901 tgagagagat ttatgaccga acccacccgc ccgatcctga ccatcaagcg acgcaaccgc
     9961 acggtctacg tcccgccgga aaaggccacg aaatctgagc cacagccagc cgaacggact
    10021 accagcaagg cgaaggtaca gccaaaagcg aaagccccgc agaagcccgc acagaagccc
    10081 acagcggcaa agccgaaaaa gacgcccgag caggtcgccg aggggatccg cagacaggag
    10141 gagaacgacc gccgccagca ggacatcgcg atcgccaaca agtccaaaaa ggcgctggcc
    10201 aaccgggtga ccaaagcatt cctgaaagag cactggcctg acttactgac ccggggagtt
    10261 gaccgtcgcc ccatggcaaa gggcatcatc gagcagatcc tgacccgagg cgcagagctg
    10321 gacatgccgc cagaggcaga ccgcaaagcc gtccgtcgca tcctgggcat tgtcacgggt
    10381 accagctcgt accagcagag cctcatcgac cagtgcatgc gctacgacct ggacggcaac
    10441 cccaccgaac cagcaacccc ggaggaggcc gaaaacgcca aagcccgcct gacagagatc
    10501 aaggcattcc ggcgcaaggc acgccaggcg aagggcgaaa aaaagggcgc ataacgcgcc
    10561 ccgtctcacc gtttcaccgc cctgtcgacc ggggctgttc ccgtctcacc cagcgccacg
    10621 taggcgcagc acgacgctct gcagcacggc gagcagctgc gacacgttga gcctgtcccc
    10681 ttgcccgtcg ggcagcaatg accccgtcgg ggatcaccac ttcaggaatg accaggcgcg
    10741 agacagcaaa ttcactcatc gccacccccg aacgtctcgg acaggttcac gccgtttgca
    10801 cgctgctcca gcgcctcgcc agccgcagca acatcgggat ccgaagcaac cagctcccgg
    10861 gtgcgcttgc gctggaaccg cagtcccagc gcgtacagag acgcatccga acggacgaaa
    10921 gcatccgtct ggccacccgc agcgagcgat ccccggaacc tgccaagcgc ccgccgctca
    10981 gtgaccgatc gatcgcccgg gtggagccgc agaacgggca acagccagat cagctccagc
    11041 cgttgcgagc gcgtgatcct gctggacagc ggcatcaaca cctcgccctg caggtgacgc
    11101 ggcagcttac gcattccagt caataccacg cgcagccggt gacagcgtca tgccacccgc
    11161 ctgaacctga cgacgcacct cggcaaacgc cggagcacgc gcc
//
