LOCUS       NZ_CP131888             8970 bp    DNA     circular CON 25-APR-2024
DEFINITION  Acinetobacter baumannii strain 2008S11-069 plasmid p2008S11-069-3,
            complete sequence.
ACCESSION   NZ_CP131888
VERSION     NZ_CP131888.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36766192
            Assembly: GCF_038441195.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 8970)
  AUTHORS   Chen,F.-J., Liao,Y.-C. and Chiu,Y.-T.
  TITLE     Rapid Diagnostics and Real-time Genomic Surveillance System for
            Pathogens from Culture
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8970)
  AUTHORS   Chen,F.-J., Liao,Y.-C. and Chiu,Y.-T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2023) National Institute of Infectious Diseases
            and Vaccinology, National Health Research Institutes, No. 35, Keyan
            Road, Zhunan Town, Miaoli County 350, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 27-FEB-2018
            Assembly Method                   :: CCBGpipe v. 1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80x
            Sequencing Technology :: Oxford Nanopore MinION and Illumina iSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_038441195.1-RS_2024_04_25
            Annotation Date                   :: 04/25/2024 19:56:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,982
            CDSs (total)                      :: 3,885
            Genes (coding)                    :: 3,813
            CDSs (with protein)               :: 3,813
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 18 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP131888.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8970
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="2008S11-069"
                     /isolation_source="Abs/pus/wd"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="p2008S11-069-3"
                     /geo_loc_name="Taiwan"
                     /collection_date="2008"
                     /collected_by="NHRI"
     gene            7..957
                     /gene="repM"
                     /locus_tag="Q7571_RS19860"
                     /old_locus_tag="Q7571_19895"
     CDS             7..957
                     /gene="repM"
                     /locus_tag="Q7571_RS19860"
                     /old_locus_tag="Q7571_19895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786597.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001205343.1"
                     /translation="MRDLVVKDNALINASYNLDLVEQRLILLAIVEARESGKGINANDP
                     LEVHADSYINQFGVHRNTAYQALKDACKDLFARQFSYQEKKANGNIRNVMSRWVSQIAY
                     NDNEATVDLIFAPAVVPFITRLEEQFTKYELQQVSSLSSAYAIRLYELLIQWRSTGKTP
                     TIELQEFRKKLGVLDNEYLRMAHLKERVLELSIKQINEHTDITVKYEQHKRGRSISGFS
                     FTFKQKKKDSPSIERDPNTLELFSKMTDAQRHMFANKLSELPEMGRYSQGTESYQQFAV
                     RIAEMLQDPAQFKELYPYLKKVGYMPSNKKDTVNG"
                     /name="repM"
     gene            950..1525
                     /locus_tag="Q7571_RS19865"
                     /old_locus_tag="Q7571_19900"
     CDS             950..1525
                     /locus_tag="Q7571_RS19865"
                     /old_locus_tag="Q7571_19900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_001096616.1"
                     /translation="MAKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRC
                     FGEPEQTSQKIESSKQEGDESTKKLIAHLENEVKKYQEREERLMQQIDRMQTLIELKSV
                     APATAAPHQDATACDTKMPQHATTQQDTDNKKNNELNIAENVAVPQQETTAYHTQTLQH
                     ATLQSVAVPQHKKRGLFGRVLNAVFDND"
                     /name="plasmid replication DNA-binding protein"
     gene            1545..1688
                     /locus_tag="Q7571_RS19870"
                     /old_locus_tag="Q7571_19905"
     CDS             1545..1688
                     /locus_tag="Q7571_RS19870"
                     /old_locus_tag="Q7571_19905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125246.1"
                     /translation="MPKLKDIALGIIVAPLLIPIMLIASYQDKKALKKELDECQKEKDQ
                     AS"
                     /name="hypothetical protein"
     gene            complement(1871..2698)
                     /locus_tag="Q7571_RS19875"
                     /old_locus_tag="Q7571_19910"
     CDS             complement(1871..2698)
                     /locus_tag="Q7571_RS19875"
                     /old_locus_tag="Q7571_19910"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057689930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /protein_id="WP_000713530.1"
                     /translation="MKKFILPIFSISILVSLSACSSIKTKSEDNFHISSQQHEKAIKSY
                     FDEAQTQGVIIIKEGKNLSTYGNALARANKEYVPASTFKMLNALIGLENHKATTNEIFK
                     WDGKKRTYPMWEKDMTLGEAMALSAVPVYQELARRTGLELMQKEVKRVNFGNTNIGTQV
                     DNFWLVGPLKITPVQEVNFADDLAHNRLPFKLETQEEVKKMLLIKEVNGSKIYAKSGWG
                     MDVTPQVGWLTGWVEQANGKKIPFSLNLEMKEGMSGSIRNEITYKSLENLGII"
                     /name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
     gene            3007..3294
                     /locus_tag="Q7571_RS19880"
                     /old_locus_tag="Q7571_19915"
     CDS             3007..3294
                     /locus_tag="Q7571_RS19880"
                     /old_locus_tag="Q7571_19915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_000438827.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRYTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            3281..3595
                     /locus_tag="Q7571_RS19885"
                     /old_locus_tag="Q7571_19920"
     CDS             3281..3595
                     /locus_tag="Q7571_RS19885"
                     /old_locus_tag="Q7571_19920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_001983304.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="BrnA antitoxin family protein"
     gene            3723..6134
                     /gene="znuD2"
                     /locus_tag="Q7571_RS19890"
                     /old_locus_tag="Q7571_19925"
     CDS             3723..6134
                     /gene="znuD2"
                     /locus_tag="Q7571_RS19890"
                     /old_locus_tag="Q7571_19925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /protein_id="WP_000932953.1"
                     /translation="MLNKSKLFLALITLGASKILLAAEGPVTTLNTIVLTAQSDELGSE
                     LLGKSLNVSNQFIDTSKLKQRSTTLGDALGTELGIHSNQYGGGASTPIIRGQEGKRIKV
                     LQNNADVLDMSNMSPDHAVTVEPSLAKSIEIIRGASTLLYSSNSAAGVVNVIDYKIPTQ
                     MPQDGLEGNTTLRFNTGSNEKLTTAGVTVGLSPHVALRAEGLYRNAGNYKTPHYQSSSY
                     NSLEDLENQNSIYKNLKYLPESWAESRVGTLGLSWIDDNTYLGVSYTHRHDEYGLPAHS
                     HLYEGCGASAIGIDSRISGLKNYLLYYPQLMDEQDINYINPRPDCHQHNHIHETNFSHN
                     APYIDLNTRRYDVRGEFTQPFTGIDKIRTSLSYIDYFHNELEGDKITNFFKNTGKVGRI
                     ELSHQPLGELTGILGLQYLEQDNSALSPVHSQEGHTTYLDNQQLLNRNVTKNFSVFGLE
                     KYNWNDFTFELGARIEKQKVSMDYDIEKIKDSMKPWPNKYNSPYVEKNNKIRAQNLKSI
                     LEAVQPNKETAFSYAGTVHWRFAPNYILSLTGTHQERLPNAQEMYTHGMHLATNSFEIG
                     NRFLRKEKSNNLEISLAYKDDLLDYQISTYYYDFDNYIYLQTLNEVLGTTKVRDQHTLR
                     INHYSQSAANFYGLEGNIGYQFNSVYHGSLFGDYVKGRLTNLPDAVIAYDIWNREPTLA
                     PQKDRYTPRLPPARLGTRLKADFDESLKGEIEYYRVFKQDNISKFEQVTSGYNMLNMTL
                     AYKNKLSHTEYDLFFKANNLLDQKVYAHETFLPYIPQIGRNFSLGLNLNF"
                     /name="znuD2"
     gene            6439..6900
                     /locus_tag="Q7571_RS19895"
                     /old_locus_tag="Q7571_19930"
     CDS             6439..6900
                     /locus_tag="Q7571_RS19895"
                     /old_locus_tag="Q7571_19930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /protein_id="WP_000761346.1"
                     /translation="MKLAEALLLRSDQQKKIISLKQRINANVLVQDGDQPSEDPNELLK
                     QVFSLIQEFQKLSYAIHETNALTKLNDGRSLLALLTLRDEFVEQHKTLTAAISNTSRES
                     DRYSTREIKWHKVIPVSSLQKQADDISLKLRDLNVLIQSTNWKIDLIEA"
                     /name="DIP1984 family protein"
     gene            complement(7223..7396)
                     /locus_tag="Q7571_RS19900"
                     /old_locus_tag="Q7571_19935"
     CDS             complement(7223..7396)
                     /locus_tag="Q7571_RS19900"
                     /old_locus_tag="Q7571_19935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001282484.1"
                     /translation="MSDNIIQLSKPCTLCENRQNVQLFAGLMLCGSCQENIRLTNPSMF
                     SANDEIEQKAQN"
                     /name="hypothetical protein"
     gene            complement(7396..7767)
                     /locus_tag="Q7571_RS19905"
                     /old_locus_tag="Q7571_19940"
     CDS             complement(7396..7767)
                     /locus_tag="Q7571_RS19905"
                     /old_locus_tag="Q7571_19940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000504218.1"
                     /translation="MGEKVKTYAVRLDPQVAEFYDQLANSEGIRTSKLFSKILTNDFQS
                     IAVKQQADRIEDLVNRLEKRIDDFEEDNNFSEKYYEDFSGLYFMMLWLLMKNGASKDEV
                     RMIQAKGYSYADDNYKRVK"
                     /name="hypothetical protein"
     gene            complement(8039..8293)
                     /locus_tag="Q7571_RS19910"
     CDS             complement(8039..8293)
                     /locus_tag="Q7571_RS19910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001014303.1"
                     /translation="MNGQKIDFLRFSKQGNKYFFPCKTKHRPYVTLANFPIQDPAHAGI
                     FLSHTTHLTMTPLKALQDKDFSDFLGSQKRVQKNGLFLE"
                     /name="hypothetical protein"
     ARG             complement(1875..2698)
                     /name="blaOXA-72"
                     /gene="blaOXA-72"
                     /gene_name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          8..957
                     /name="rep_cluster_1172"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtggctatga gagatttagt tgtaaaggac aatgccttaa tcaacgcaag ctataactta
       61 gacttagtag aacaacgttt aattttattg gctattgttg aagcaaggga aagtgggaaa
      121 gggattaatg caaatgatcc attagaagtt catgcagata gttatatcaa tcaatttggt
      181 gtacaccgta atacagctta tcaagcctta aaagatgctt gtaaggattt attcgcgcgt
      241 caatttagct atcaagagaa aaaagctaat gggaatatcc gaaatgttat gagtcgttgg
      301 gtatctcaaa ttgcttataa cgacaatgaa gcaactgtag acttaatatt tgcacctgct
      361 gttgttccct tcataacccg actggaagaa caatttacta aatatgaatt acagcaagtt
      421 agtagtctta gtagcgctta tgccattcgc ttatatgagc ttctaattca gtggcgaagc
      481 actggtaaaa ccccaaccat agaactacaa gaatttagaa agaagttagg cgttcttgat
      541 aatgaatatt tacggatggc tcatttaaaa gagcgtgttt tagagctttc aattaaacaa
      601 ataaatgagc atacggatat aactgtaaaa tatgaacagc ataaaagagg acgttctatt
      661 tcaggatttt cttttacctt taaacagaag aagaaggata gcccatcaat agaaagagat
      721 ccgaacactt tggagctttt ttcaaagatg accgatgctc aacggcatat gtttgcaaat
      781 aaactttcag aactccctga aatgggtcgc tattcacaag gaacagaaag ctaccaacag
      841 tttgctgtac gtattgctga gatgctacaa gatcccgctc aattcaaaga gctataccca
      901 tacctaaaaa aagtgggata catgccatca aataaaaagg acaccgtaaa tggctaagtt
      961 atcactaagt gaagtatcta aaaaatttca tgtggataga tcaaccattt acagagctgt
     1021 acgtaatgga cgtttatcac gctccagtga tggacaattc gatctagcag aggtcatacg
     1081 atgctttgga gaacctgagc aaacatctca aaaaattgaa tcatctaagc aagaaggtga
     1141 tgaatctaca aaaaaactta ttgcccattt agaaaatgaa gtcaaaaaat accaagaacg
     1201 tgaagaacgg ttaatgcaac aaattgaccg tatgcaaaca ctcattgagc tgaaaagtgt
     1261 tgcacctgcc acagcagcac cacaccaaga tgctacggca tgcgacacca agatgccaca
     1321 gcatgcgaca acacaacaag acactgataa caaaaagaat aatgaattaa atattgcaga
     1381 aaatgtagca gtgccacagc aagaaactac ggcataccac acccaaacgc tacagcatgc
     1441 cacgttgcaa agtgtggcag tgccacaaca caaaaaacgt ggtttatttg gccgtgtgct
     1501 gaatgccgtc tttgataatg actgagcaat aagggtgaaa gatcatgccg aaactgaaag
     1561 acattgccct gggaattatt gtagctccgc tgctgatccc gatcatgctg attgcatcgt
     1621 accaggataa aaaggcgctg aagaaagagc tggatgaatg ccaaaaagaa aaagaccagg
     1681 catcctgatt attcaattga gctaatcaaa agtgtggaac attgatgaaa taatagcgtg
     1741 gaacgtgaaa agtcataaaa aaagcccgaa cagggatgct cgggctataa actagaaact
     1801 acagcgttga attataagga taattataca gcatttcgta taaggcgtat tatgttaatt
     1861 ttagaaatta ttaaatgatt ccaagatttt ctagcgactt ataagtaatt tcattacgaa
     1921 tagaaccaga cattccttct ttcatttcta agttgagcga aaaggggatt ttttttccat
     1981 tagcttgctc cacccaacca gtcaaccaac ctacctgtgg agtaacatcc attccccatc
     2041 cactttttgc ataaatctta ctaccattta cttctttaat tagaagcatt tttttaactt
     2101 cttcttgagt ttctaattta aaaggtaatc ggttatgtgc aaggtcatcg gcaaaattaa
     2161 cttcttgtac tggtgtaatt ttaagggggc caactaacca aaaattatcg acctgtgttc
     2221 caatatttgt atttccaaaa ttaacccgct ttacttcttt ctgcattagc tctaggccag
     2281 tccgtcttgc aagctcttga tatactggaa ctgctgacaa tgccattgcc tcacctaaag
     2341 tcatatcttt ctcccacata ggataagttc tttttttacc atcccatttg aaaatctcat
     2401 ttgttgttgc tttatgattt tctagcccga ttaaagcatt tagcatctta aatgttgatg
     2461 cagggacata ttctttattt gctcgtgcaa gagcattacc ataggtgcta agatttttac
     2521 cctctttaat aataattaca ccctgtgttt gagcttcatc aaaatagctt ttaatagctt
     2581 tttcatgttg ctgagaagaa atatgaaaat tatcttcaga tttagtttta atagatgaac
     2641 atgcactgag agaaactaga atagaaatgc tgaatatagg aagtataaat tttttcatta
     2701 caaattcatg ttaggggaaa ttttggggct tagagtataa tatttttatt aaaaaagtta
     2761 aaactctttt aatttaacat aatggatatt atacgaagta cacttgtata ttaatttaaa
     2821 tatcaactac ttaataaaaa tataaaaatc caaaaatgcc caaaaagccg actttgaaac
     2881 aagtcggctt ttttatgatc gattttgata gtttttgcca ataaatctga ctaaaaatta
     2941 cgcttctcaa cttgagtgat acaatttcgt gatacattat tgtatataca aatttgaata
     3001 ttttttatgg aacagtattt tgaatgggat gaggctaaga atcgaaagaa tcagaaaaag
     3061 catgatatct ctttcgaaac tgcaagcctt gtttttgaag atccattacg gatctcaatc
     3121 caagacagat atactaatgg tgaagaacgt tggcaaacca ttggacgagt taaaggcgta
     3181 ctaatgttat tggtggctca caccattttt gatgaagatg actgtgaaat catccgaatc
     3241 attagtgcaa ggcaagtcac taaagcggag cgaaacaaat atgagcatgg ttagatactc
     3301 acacaaagag ctgaatgaga aatttggtga gaagcaagat gctgaaattc aacgcttgct
     3361 tgctaaaggc acggttcctg atgatcagct agatctatca gatattcctg aaattacaga
     3421 ctggagcaat gctgtacgcc aaaatcaatt ttaccgccca gtaaagcaac aaacttcaat
     3481 tcggttagat gctgatgtac ttgcttggtt caaagcacaa ggcaaaggtt atcaaacacg
     3541 tatgaatgaa attttacgag atgctatgct aaaagaatta aaaaatcatc aataagaatg
     3601 ggagcttagg ctcccatttt tgacttcatt tttagggggg attaccattc aaaaatttaa
     3661 atagtagatt ttataaattt ttaagtgtta tattataata taacattaaa tttggttgtt
     3721 ttatgctaaa taaaagtaaa ctatttttag ctttaattac tttaggggcc tcgaaaattt
     3781 tattggcagc tgaagggcct gttactacct taaatacaat agtattaact gcacaatctg
     3841 atgagttagg gtctgagctg ttaggcaaaa gtctaaatgt tagtaatcag tttattgata
     3901 ctagtaaact taaacagcgt tcgacaactc taggggatgc cttgggtacg gaattaggaa
     3961 ttcattctaa tcaatatgga ggtggagcat ctactcctat tattcgtggg caggaaggaa
     4021 aacgtattaa agttttacag aataatgctg acgtgttgga tatgtctaat atgtctccag
     4081 atcacgctgt cacagttgaa ccaagtttag ctaagtctat tgaaattata cgtggtgcaa
     4141 gtaccctttt gtatagttca aatagtgcgg caggggtagt caatgtcatt gactataaaa
     4201 ttccaaccca aatgcctcaa gacggattag agggtaatac tacattacgt tttaatactg
     4261 gcagtaatga gaagttgacc acagcaggtg taacagttgg cttaagccca catgtagctt
     4321 tacgggcaga agggttatat cgtaatgctg gtaactataa aactcctcat taccagtcta
     4381 gctcttataa ttctttagaa gatcttgaaa accaaaacag tatttataaa aatttaaaat
     4441 atttaccaga aagctgggca gagtcgagag taggtacgct tggattatcc tggatagacg
     4501 ataatactta tttaggagtt tcttatacac atcgtcatga tgaatatggt ttaccagccc
     4561 atagccattt atatgaaggt tgtggtgcct ctgcaatcgg tatcgattca cgaattagtg
     4621 gattaaaaaa ttatctttta tattatcctc aattgatgga tgagcaagat attaattaca
     4681 taaatccacg tcctgattgt catcagcata atcatattca tgaaactaat ttctctcata
     4741 atgctcctta tattgattta aatactcgac gttatgatgt gcgtggagaa ttcactcaac
     4801 catttaccgg tattgacaaa attcgtacct cattgagtta tatagattat tttcacaatg
     4861 aactcgaggg agataagatt actaactttt ttaaaaatac aggaaaagta ggccgcatag
     4921 agttatcaca tcagccatta ggggaattaa ccggtatctt ggggctacaa tatttggaac
     4981 aggataatag tgctttatca ccagtccatt ctcaagaagg ccataccacc tatctagata
     5041 atcagcagct attaaatcga aatgtcacta aaaactttag tgtatttggc ctagaaaaat
     5101 ataactggaa cgactttact ttcgaactag gtgctcgtat agaaaagcag aaagttagta
     5161 tggattatga tatagaaaaa attaaagatt caatgaaacc ttggcctaat aaatataaca
     5221 gtccttatgt agaaaaaaat aataaaatca gggctcaaaa tttaaaatct attttagaag
     5281 ctgttcaacc taacaaagaa acagcttttt cttatgcagg tacagtccac tggagatttg
     5341 ctccaaatta tatcttatca ttaacaggta cacatcaaga aagattacct aatgcacaag
     5401 aaatgtatac tcatggtatg catctcgcta ctaattcttt tgaaataggt aaccgctttc
     5461 taagaaaaga gaaatccaat aatttagaaa tcagtctggc ctataaggat gatttacttg
     5521 attatcaaat cagtacttac tattatgatt ttgataacta tatatattta cagacactca
     5581 atgaagtttt aggaactaca aaagttagag atcagcatac actacgtatt aatcattata
     5641 gccagtctgc tgctaatttt tatggattag agggcaacat agggtatcaa tttaattctg
     5701 tttatcacgg ctctcttttt ggagattatg tgaaaggccg tttaacaaat ttacctgatg
     5761 ctgtaattgc atacgatatc tggaatagag aaccgacttt agctccccaa aaggatcgtt
     5821 acactcctag attacctcct gctcgtttgg gtacacgact aaaagctgat tttgatgaat
     5881 cgcttaaagg tgaaatagaa tattatcgag tctttaaaca agataatatt tctaaatttg
     5941 agcaggttac atcaggttat aatatgctta atatgacttt agcatataaa aataagctat
     6001 ctcacacaga atatgattta ttctttaaag cgaataattt acttgatcag aaagtctatg
     6061 cccatgaaac atttttgcca tatattcccc aaattggaag aaattttagt ttaggcttaa
     6121 atcttaattt ctagataaga tactgtaatc ttctaagaaa atttcttaga agatttttct
     6181 tataaaatga ttagattaat aattaaggta agcgtccgct gaatcccata cctatttttt
     6241 aattcgattt aggtttccag cagtgtggca gtaactcttc aatctgggtc actttatgtg
     6301 tcggcagcct tttcagcact gaatagccac cgattttgta gacacctttt agctagataa
     6361 aaagcaattt ttttgatctt taaagaatga ggatataagc tgtttaaaac ttaattctaa
     6421 ttggttaata ggtgaaaaat gaaattagca gaagctctct tacttcgaag tgatcaacaa
     6481 aaaaaaatta tttcactaaa acaacgtatc aatgcaaatg tattggtaca agatggtgat
     6541 caaccatctg aagatccaaa tgaactacta aaacaagtat tttctttaat tcaagaattt
     6601 caaaaattaa gttatgcaat tcatgaaact aatgctttaa caaaattaaa tgatggccgt
     6661 tctctacttg ctttattgac tttgcgtgat gaatttgtag aacagcacaa aaccctaact
     6721 gcagcaataa gtaatacatc tcgtgaatct gatcgttata gtacgcggga aataaagtgg
     6781 cataaagtta ttccagtttc atcattacaa aaacaagctg atgatattag tcttaaatta
     6841 cgtgatttaa acgtgttaat tcagtcgact aattggaaaa ttgatttgat tgaagcctaa
     6901 tagtccttta gatataatca agttgaacat actgggcgag tacaagatcc cttacttcca
     6961 caacatagga ttgtaaataa agtgtagtgg cttgcaaagc aagtggataa gcttaaaatt
     7021 ttaagtacaa atcaatccat cacttggcat aactcaaatc tttgtgcaaa caaagttaca
     7081 cgttacttat aactaccatg tactgacagt atgttcacct caattactaa aaataaagaa
     7141 atgagcaagc atcagctcaa ctacatttct atttttaatt catttcggca tttaacataa
     7201 aatctcttat acgaagccca ggttaattct gggctttttg ttcaatctca tcattggccg
     7261 agaacatact tggattcgta agcctgatat tttcctgaca acttccacac agcatcaatc
     7321 ctgcaaaaag ttgtacattt tgtctatttt cacaaagcgt acatggcttt gaaagctgaa
     7381 taatattatc tgacactact ttaccctctt atagttatca tctgcatatg aataaccttt
     7441 agcttgtatc attctaacct catctttaga agcgccattt ttcattaaga gccacaacat
     7501 catgaaatat agtccagaaa agtcttcata gtatttttca gaaaaattgt tatcttcctc
     7561 aaaatcatct attcgctttt ctaatcgatt caccagatcc tcaatacgat cggcttgctg
     7621 tttaacagca atagattgaa aatcattggt caaaatttta ctgaataatt tactggttct
     7681 gattccttct gaattagcca attgatcgta gaattctgct acttgtggat ctaacctgac
     7741 tgcataagtt ttgacttttt cgcccataaa ttacacctct tattaaaatt agattttgta
     7801 caaaattaaa tatatataat tcaactaatt aaataaaaaa taataattag attacgtaca
     7861 aacttatttg tacagaatta atttattcta aaacaaaaac ttatttaaat ataatgcttt
     7921 ttttatgtac aatcatgagt acatattttt tcttaaattt atcaatatct tatctaaaaa
     7981 aagtgttgtt ttgatgtaca accatgagca cagcataaaa aatagataat tcaatcactt
     8041 attctaaaaa aagaccattt ttctgtacac gtttctgaga ccctaaaaaa tcgctgaaat
     8101 ccttatcctg taaggctttg aggggtgtca tcgttagatg cgtggtgtgt gacaaaaaaa
     8161 tcccggcatg tgccggatct tggattggaa aattggctaa agtgacgtag ggccggtgct
     8221 tggttttgca tggaaaaaag tatttatttc cttgtttaga aaaacgtaaa aaatcaattt
     8281 tttgtccatt catccaggtt aaaaatttca acccaaaact ttaattatga aaagcttcat
     8341 agaacgcgtt caaatgcgat ttaagagcct ttacctagaa aacatagatc tcatagtgaa
     8401 aaacacaaaa cagctcaaaa aacgcaaatg agagcgaaat aaagaggtat tttgacttta
     8461 gatagatgca tagagcgagt gtctacgagc gaactatcaa aatttgcgcc tagaccctct
     8521 gaaaaacatt tttttgtcct ctttagccta agaaagcgta agtttcgtgc agaaatttgc
     8581 tcctggatcg agcgtagcga gtaaaaaagt tttatgagcg aagcgaattc caagtttctt
     8641 ttgctttttt ttaaagtcac gccagtatta accaaaaaat tgccccaacg aactgagcga
     8701 aagcgaagtt caatagagtt tgagcgaagc gaaaaccaag ggcaattttt cattccctgg
     8761 gcttttaatt attttaaagt ttttaaatac ttttaaatgg cttgaaagcc ttatgaataa
     8821 agggttttag ctcttatatg tccacgttta ccttgcaata tgtccacgtt taccttgcaa
     8881 tatgtccacg tttaccttgc aatatgtcca cgtttacctt gcattagtac acaaataata
     8941 ttaacgtgta cttatacaca ataaaaaata
//
