LOCUS       NZ_CP130661            19458 bp    DNA     circular CON 01-AUG-2023
DEFINITION  Klebsiella pneumoniae subsp. pneumoniae strain SM117 plasmid
            pSM117_2, complete sequence.
ACCESSION   NZ_CP130661
VERSION     NZ_CP130661.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36664845
            Assembly: GCF_030552935.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 19458)
  AUTHORS   Bao,D.
  TITLE     Genomic characteristics of a carbapenem resistant Klebsiella
            pneumoniae isolate
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19458)
  AUTHORS   Bao,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUL-2023) Department of Clinical laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/30/2023 16:17:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,225
            CDSs (total)                      :: 6,101
            Genes (coding)                    :: 5,800
            CDSs (with protein)               :: 5,800
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 301
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 301
            Pseudo Genes (frameshifted)       :: 162 of 301
            Pseudo Genes (incomplete)         :: 151 of 301
            Pseudo Genes (internal stop)      :: 28 of 301
            Pseudo Genes (multiple problems)  :: 40 of 301
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP130661.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19458
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="SM117"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /plasmid="pSM117_2"
                     /geo_loc_name="China: Sanmen"
                     /collection_date="2023-01-19"
                     /collected_by="Danni Bao"
     gene            join(18214..19458,1..717)
                     /locus_tag="Q4S50_RS00425"
                     /old_locus_tag="Q4S50_00425"
     CDS             join(18214..19458,1..717)
                     /locus_tag="Q4S50_RS00425"
                     /old_locus_tag="Q4S50_00425"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_063938523.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIVWCAGGLV
                     AGILLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMGTNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEY
                     QPEAGRQRPGDDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            717..1448
                     /gene="mobC"
                     /locus_tag="Q4S50_RS00430"
                     /old_locus_tag="Q4S50_00430"
     CDS             717..1448
                     /gene="mobC"
                     /locus_tag="Q4S50_RS00430"
                     /old_locus_tag="Q4S50_00430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071653262.1"
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGASGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            1455..1985
                     /locus_tag="Q4S50_RS00435"
                     /old_locus_tag="Q4S50_00435"
     CDS             1455..1985
                     /locus_tag="Q4S50_RS00435"
                     /old_locus_tag="Q4S50_00435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938511.1"
                     /translation="MALYMVFIEDAEDRDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERDKPAGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQISAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(2013..2192)
                     /locus_tag="Q4S50_RS00440"
                     /old_locus_tag="Q4S50_00440"
     CDS             complement(2013..2192)
                     /locus_tag="Q4S50_RS00440"
                     /old_locus_tag="Q4S50_00440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_021515244.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGKE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            2261..2638
                     /locus_tag="Q4S50_RS00445"
                     /old_locus_tag="Q4S50_00445"
     CDS             2261..2638
                     /locus_tag="Q4S50_RS00445"
                     /old_locus_tag="Q4S50_00445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938513.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQIETHERDGLRLSDETEKMASDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTSRRWWQWGKR"
                     /name="hypothetical protein"
     gene            complement(2700..2999)
                     /locus_tag="Q4S50_RS00450"
                     /old_locus_tag="Q4S50_00450"
     CDS             complement(2700..2999)
                     /locus_tag="Q4S50_RS00450"
                     /old_locus_tag="Q4S50_00450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_063938515.1"
                     /translation="MPYEVEWKQGAIEDVTALFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2989..3252)
                     /locus_tag="Q4S50_RS00455"
                     /old_locus_tag="Q4S50_00455"
     CDS             complement(2989..3252)
                     /locus_tag="Q4S50_RS00455"
                     /old_locus_tag="Q4S50_00455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938517.1"
                     /translation="MSNSTHYENANFLRELAERLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            3629..4648
                     /locus_tag="Q4S50_RS00460"
                     /old_locus_tag="Q4S50_00460"
     CDS             3629..4648
                     /locus_tag="Q4S50_RS00460"
                     /old_locus_tag="Q4S50_00460"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="WP_304394122.1"
                     /translation="MAITIKSAVNVRSRVLIYSLLLFTGSAYAADIAESTFLTRDIGNG
                     LYEMSFDGKNNSLWAASSSSFDRDKGHGIVYQLEPSTLKTKSAVKIARLGFATALDEEH
                     ERLYIGNTLDGSVTVIDTLTGKELSVIPLTEGQDEAHFRPTREMVIDKKNQRLYVSSAA
                     DKGALWVIDMAVGKKIKTIDGLGHAVTGIALNKNGDNIYLVNGDGEIINLDASSYEIKK
                     RFVVEPEKKHFFLNVSLDEKNGRAFITDPDIPGVLVVDVNSGKILHRIDVINSLAILFN
                     PLRNEIYITHRNAKQVSIVDSNSYYVKTTIKTRLMPNSLSLSHDGENLYVSVKQEKKR"
                     /name="YncE family protein"
     gene            4710..6899
                     /locus_tag="Q4S50_RS00465"
                     /old_locus_tag="Q4S50_00465"
     CDS             4710..6899
                     /locus_tag="Q4S50_RS00465"
                     /old_locus_tag="Q4S50_00465"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_063938521.1"
                     /translation="MNKYLGLSIVYMMYTSSVMADDSGAVSKDKNISPEETLIVHGTAV
                     SESTTEGTDSYTTQSANTASKMNLSFRDTPQSTTVITRRRMDDVAAKNIIDVVKTAPGL
                     YVSTAEGSGRPNFMSRGFNANVMYEGFSLPWNSYIPSSQTSSAIFDRVEIVRGATGLVQ
                     GAGDPSAAINMIHKRPTRQYQASTNIGAGRWNDYRGGVDVSGPLNDSATLRGRAVVDGE
                     NSETFRDSEKRRNNVIYGIMEADLTDNTLLTIGGYQQYEYNNHWWYDLPISGTGHHLNL
                     PRSTFTGNDWEFERSKSKTAFATLEQKFSNSWKLKFSTLQNWRNADLLGTATYRHKDTR
                     QSMYQQVWGSLREYNSKSYDLSLNGDYALFGRVHQFVAGTTQQKYTDKDTGYTYSPIYI
                     ENVNIFDHGSHSSKKPMKMSGDASYDVTEQKSAYAATHFLLSDNWKILLGGRLDWYEYT
                     SKGTSINTGYKVTRNITKYAGSTYNLDDHHTIYGSYTDIFNPQSSTDLNGKVIKPIVGK
                     NYETGIKGEYFNGLLNASLAVFQVDQENRARLLPDQTGCVTNGNPQCYEASGKVRTKGI
                     DFELQGMVTPLWEIGVGYTYADTRYIKDGDRSNEGKRFNTAVSPQNLFKISSMYTFDGK
                     LTNWRAGVNTYWQSKIYANITDTRDGNPVINKQKAYSTTDIIIGYTPMPQLDLQLNITN
                     VFDKVYYTSIGESIGYGTETYGEPRNVKISATYRF"
                     /name="TonB-dependent siderophore receptor"
     gene            8485..10446
                     /locus_tag="Q4S50_RS00470"
                     /old_locus_tag="Q4S50_00470"
     CDS             8485..10446
                     /locus_tag="Q4S50_RS00470"
                     /old_locus_tag="Q4S50_00470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_063938523.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIVWCAGGLV
                     AGILLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMGTNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEY
                     QPEAGRQRPGDDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            10446..11177
                     /gene="mobC"
                     /locus_tag="Q4S50_RS00475"
                     /old_locus_tag="Q4S50_00475"
     CDS             10446..11177
                     /gene="mobC"
                     /locus_tag="Q4S50_RS00475"
                     /old_locus_tag="Q4S50_00475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071653262.1"
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGASGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            11184..11714
                     /locus_tag="Q4S50_RS00480"
                     /old_locus_tag="Q4S50_00480"
     CDS             11184..11714
                     /locus_tag="Q4S50_RS00480"
                     /old_locus_tag="Q4S50_00480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938511.1"
                     /translation="MALYMVFIEDAEDRDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERDKPAGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQISAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(11742..11921)
                     /locus_tag="Q4S50_RS00485"
                     /old_locus_tag="Q4S50_00485"
     CDS             complement(11742..11921)
                     /locus_tag="Q4S50_RS00485"
                     /old_locus_tag="Q4S50_00485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_021515244.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGKE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            11990..12367
                     /locus_tag="Q4S50_RS00490"
                     /old_locus_tag="Q4S50_00490"
     CDS             11990..12367
                     /locus_tag="Q4S50_RS00490"
                     /old_locus_tag="Q4S50_00490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938513.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQIETHERDGLRLSDETEKMASDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTSRRWWQWGKR"
                     /name="hypothetical protein"
     gene            complement(12429..12728)
                     /locus_tag="Q4S50_RS00495"
                     /old_locus_tag="Q4S50_00495"
     CDS             complement(12429..12728)
                     /locus_tag="Q4S50_RS00495"
                     /old_locus_tag="Q4S50_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_063938515.1"
                     /translation="MPYEVEWKQGAIEDVTALFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(12718..12981)
                     /locus_tag="Q4S50_RS00500"
                     /old_locus_tag="Q4S50_00500"
     CDS             complement(12718..12981)
                     /locus_tag="Q4S50_RS00500"
                     /old_locus_tag="Q4S50_00500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063938517.1"
                     /translation="MSNSTHYENANFLRELAERLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            13358..14377
                     /locus_tag="Q4S50_RS00505"
                     /old_locus_tag="Q4S50_00505"
     CDS             13358..14377
                     /locus_tag="Q4S50_RS00505"
                     /old_locus_tag="Q4S50_00505"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="WP_304394122.1"
                     /translation="MAITIKSAVNVRSRVLIYSLLLFTGSAYAADIAESTFLTRDIGNG
                     LYEMSFDGKNNSLWAASSSSFDRDKGHGIVYQLEPSTLKTKSAVKIARLGFATALDEEH
                     ERLYIGNTLDGSVTVIDTLTGKELSVIPLTEGQDEAHFRPTREMVIDKKNQRLYVSSAA
                     DKGALWVIDMAVGKKIKTIDGLGHAVTGIALNKNGDNIYLVNGDGEIINLDASSYEIKK
                     RFVVEPEKKHFFLNVSLDEKNGRAFITDPDIPGVLVVDVNSGKILHRIDVINSLAILFN
                     PLRNEIYITHRNAKQVSIVDSNSYYVKTTIKTRLMPNSLSLSHDGENLYVSVKQEKKR"
                     /name="YncE family protein"
     gene            14439..16628
                     /locus_tag="Q4S50_RS00510"
                     /old_locus_tag="Q4S50_00510"
     CDS             14439..16628
                     /locus_tag="Q4S50_RS00510"
                     /old_locus_tag="Q4S50_00510"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_063938521.1"
                     /translation="MNKYLGLSIVYMMYTSSVMADDSGAVSKDKNISPEETLIVHGTAV
                     SESTTEGTDSYTTQSANTASKMNLSFRDTPQSTTVITRRRMDDVAAKNIIDVVKTAPGL
                     YVSTAEGSGRPNFMSRGFNANVMYEGFSLPWNSYIPSSQTSSAIFDRVEIVRGATGLVQ
                     GAGDPSAAINMIHKRPTRQYQASTNIGAGRWNDYRGGVDVSGPLNDSATLRGRAVVDGE
                     NSETFRDSEKRRNNVIYGIMEADLTDNTLLTIGGYQQYEYNNHWWYDLPISGTGHHLNL
                     PRSTFTGNDWEFERSKSKTAFATLEQKFSNSWKLKFSTLQNWRNADLLGTATYRHKDTR
                     QSMYQQVWGSLREYNSKSYDLSLNGDYALFGRVHQFVAGTTQQKYTDKDTGYTYSPIYI
                     ENVNIFDHGSHSSKKPMKMSGDASYDVTEQKSAYAATHFLLSDNWKILLGGRLDWYEYT
                     SKGTSINTGYKVTRNITKYAGSTYNLDDHHTIYGSYTDIFNPQSSTDLNGKVIKPIVGK
                     NYETGIKGEYFNGLLNASLAVFQVDQENRARLLPDQTGCVTNGNPQCYEASGKVRTKGI
                     DFELQGMVTPLWEIGVGYTYADTRYIKDGDRSNEGKRFNTAVSPQNLFKISSMYTFDGK
                     LTNWRAGVNTYWQSKIYANITDTRDGNPVINKQKAYSTTDIIIGYTPMPQLDLQLNITN
                     VFDKVYYTSIGESIGYGTETYGEPRNVKISATYRF"
                     /name="TonB-dependent siderophore receptor"
     Typing          complement(7105..7685)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.625"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16834..17414)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.625"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          718..1445
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.885"
                     /coverage="100.0"
                     /evalue="3.93e-144"
     Typing          10447..11174
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.885"
                     /coverage="100.0"
                     /evalue="3.93e-144"
ORIGIN
        1 atcgacgtgg cggggataat caacggcggc ggctgcctgt acgtcatcgg ctcgatggac
       61 gatgaggcgg tgatccgggt gcagaagatg ctgtttgccc gctgcgcgca aatcatcatt
      121 gcgcgggatg agttccggag gtggccgcac gcgagcatca tgctcgatga gattaaatac
      181 ctgctgtcga agtacgtgct gaacgcgctg gggacgctgc gcagtcggga ctgcaacctg
      241 ctgctcgcgc accagtcgct gggcgacttc gggcagtgcg gccaggatct gcccgctgag
      301 tttgtgaaaa ccacggtgct ggataacacg ccgatccgct ggttctaccg ggcggccagc
      361 caggagtccg cgcagtgggc ggcgggccag accggggaaa tccgggtgga cgtggagcgc
      421 cgccgggcca gccgggaggc ggggaacgtg gagcatatca gcggggacag cttcattcag
      481 aaggaggcgc ggccgctgtt tgacgtgaac accctgcagc acctgcctga cgggtttgcg
      541 gtgatgaccg ggctgggcgt ggcccggatg gcgttcagca gcccgctgcg ggttgaacgc
      601 cgggaaatcc cgctgcagcg cttcccggtg ctggcgaaaa cggacccgct ggcggagtac
      661 cagccggagg ccgggcggca gcggccgggt gatgatgatt ttgcggggct gtactgatgg
      721 cactggagcg atacaacgtc agccacgcga agcggcaggc gcggaacgcg gagaaaaccc
      781 ggctgaccct gcgctggctg cgggaagagc tgtgttccac ggcggagctg gttgcgcgac
      841 ggctggggat tgcggcggtg cagccggttt accgcttcct ggacagcctg gtggcgaaag
      901 ggctgctggt ccgggcgaaa tacccggttg acggccgtca ggtcagcgtg tggggactga
      961 cgccgcacgg ggtggcgttc tcgttcgacg aggacgaacc gctgacggac gttattccgt
     1021 ttcagccgtc aagggtgtcg gcggcgcagc tgccgcaccg gctggccgtg cagtccctgc
     1081 gtctcgccat ggaggcccgg ggggcctccg gctggcggta cctgcaccgt atggccctga
     1141 aggggatgaa ggtgccggac gcgctggcgg agctggacgg cagaacggtg gcgtttgagg
     1201 tggagcgcac cgtgaagagc cgcaggcgct atcaggaggt ggtgtccggg tatctgttca
     1261 atcgcaaagc gaacggcatc gatgaaatct ggtacatctg cccggaccgg gcgacgcagg
     1321 tcagggtgca gcgggcgatc ctgtcggtgg atgaaatcgt gaatccacag accggcgagg
     1381 cccgcaaaac ggcggagctg gaccgggagc ggctgtttgc gtgctttaaa tttatgacaa
     1441 cggagtgagg gattatggcg ctgtacatgg tatttattga agacgcggag gaccgggacg
     1501 gcgagcgctg catcatgccg accagcgagc atcttgaaga tatggtggtg ctcgcctggc
     1561 agaccggggc gtatgttttc tgttttgtcg accgggccca gcatctggcg atgatgaaat
     1621 ccatcgggat gtatgacgag cggctcaaca gcgacgaaaa agccacgtac tttttcaccg
     1681 gtaaaaatcc gcaatgggaa cgggacaaac ccgcaggaat gaagctgtgt gattacctct
     1741 atcgcaaggt ggagcggttc gccatcgaga acggtgtgca ggtggttgat gccgggaagt
     1801 gctcaccgga gcagattagc gcgatgattg aggtggtcag cgagcggcac ggggaaagcg
     1861 cggtgaacga gaagctgaaa gcggagctga tgcgggaata taacagccgc tattttaacg
     1921 tgccggtgcc tgaactgccg gaggacaaac ccgcccgccg gtggtggccg ttcggcaaaa
     1981 aataaacggc agcaccggcc atgccggtgc tgttattcct tcccgagctt atcccgcatc
     2041 acctgccaga gtgtttccgc atcctcgtgc agccgctcgc acatgtcggc cggggtatcc
     2101 atatccagct cgttcagttt ctcgagtaac agcagcgact ggtccttaat aaatttagcc
     2161 atattgaggg cagttttttc ctgcttagtc atgttttctg tccttccggg tgtggtgtgc
     2221 ttcctgtcgg gtatactgtc tcaaaaccgg aggtgagaca atggcgtggg tgacggtgag
     2281 acaggcgacg gaactgacgg ggaaagcccg gagttccctg tatagggata tggcgaaagg
     2341 ccgcgtatca taccgtactg aagctgatgg tggtcgggtg gtggatacca gcgaacttat
     2401 ccgggtgtac ggtgaattaa gacagattga gactcacgag cgggacgggt tgagactgtc
     2461 ggatgagact gaaaaaatgg cctccgacgc gttgatcgcg gagataaaag cactcaggga
     2521 ggaggtggcc ggactgcggc aggaaatgca ggccatgaga ctgctggaac acaaaccaga
     2581 gacagcagag acaccggccg gaacatcgcg ccgatggtgg cagtggggaa aacgctgacg
     2641 cgctgtgctt gtccaaccgg cgacggccac gcaatgaatt gcgcccccat caccggttat
     2701 cagcgaacgg tatggggatt ctggcgctgg ccaaccacgg ccagaacccg gactttcctg
     2761 gtctggtcat caacatcata gaggacatgc tgtcccatca gactgatccg gcgaacgtcc
     2821 tcgccatagc gtgagtccac ttcatatagg cgcgggaagt cggccagttt gtccgctgca
     2881 gcgagaactc gatcggtaac gttctgcgca tcccacaggg atgaattttc cgcaatgtag
     2941 tcaaacaatg ctgtcacatc ctcgatggct ccctgcttcc attccacctc atacggcatc
     3001 gcgtagttcc tgatagcggc catgcagtct ctggcggagt tgttccgtgg tcatgcccgg
     3061 gcgcgtgtca gcgcgggcgg cggtcacttt agcgcgaacc tgatcttcat attctgcctg
     3121 ggccagttct tcgttagcca ggcgctgcaa cagtgcagct ttgtccgggc caccttcagg
     3181 cagtatgcgg ggcagtctct cggccagttc ccgcaggaaa ttggcgtttt catagtgtgt
     3241 actgttgctc attgtggagc ctcccgggct gatacgtcga tatgaaggag tttagcaggg
     3301 ggcggtctga aagaatatgc tcgtgtcagt caggctgatg aagacgaaag ctggtaaaaa
     3361 agggcttacg acacccattt tacgtcaaac tgcacgacat gcagttgcgt gcatagccat
     3421 gcagcgggtt aaaatttatc aggcgcgttt ccggcggttt tccgggtggt ttgttgccgg
     3481 ttttatcccg tagccgccgg aaatgccctc agaccgtctg agcggtgcgc gtaatgcgac
     3541 gttatggtaa atcatgtgat taatggtagt gataatcatt atcacttttg ctatattctt
     3601 gtttctttta ttgtaaggaa atgtaagtat ggcaatcacg attaaatccg ccgttaatgt
     3661 ccgtagcaga gtattaatat actctttact actgtttact ggttcagcgt atgcggctga
     3721 tatagctgaa tcaacattcc tgactcgtga tatcggcaat ggtctgtatg aaatgtcttt
     3781 tgatggcaaa aataatagtc tctgggcagc atcatcgtct tcattcgaca gagataaggg
     3841 ccacggaatt gtttatcagt tagaaccatc cactctgaaa acaaaatctg ccgttaaaat
     3901 cgcacgtctt gggtttgcca cagcactgga tgaggaacat gagcgacttt atatcggcaa
     3961 tactctggac ggctcagtga cggtcattga tactctaacc ggaaaagaac tttcagtaat
     4021 tccgttaact gagggacagg atgaggctca tttcagaccg accagagaaa tggtcattga
     4081 caaaaaaaat cagcgtcttt atgtctccag cgccgcagat aaaggggctc tgtgggttat
     4141 tgacatggct gtcgggaaga aaattaaaac cattgatgga ctggggcacg ctgttactgg
     4201 aattgcgtta aataaaaatg gggataatat ttatctggtt aacggggatg gtgagattat
     4261 taacctggat gccagtagct atgaaataaa aaaacggttt gttgtagagc ctgagaaaaa
     4321 acactttttc cttaatgtaa gtctggatga aaaaaacgga cgtgcattta ttaccgaccc
     4381 ggatattccc ggggtgctgg ttgttgatgt aaactcggga aaaatactac acagaattga
     4441 tgttataaat tcactggcga ttttatttaa tcctttacgg aacgaaatct atatcacgca
     4501 ccgtaatgca aaacaggtca gcattgtgga cagtaattct tattacgtaa aaacaacgat
     4561 aaaaacccgc ctgatgccaa acagtctgtc tttatcacat gacggtgaaa atctgtacgt
     4621 tagtgtaaaa caagaaaaaa agagatgagt actatgaagg attacatact caaaatcgaa
     4681 ttatctaaaa ttgctatgga gccagaagaa tgaataaata tttagggctg agcatagtat
     4741 atatgatgta tacatcatct gttatggctg atgattctgg cgcagttagt aaagataaaa
     4801 atatttcacc agaagaaaca ttaattgttc atgggaccgc tgtttctgaa agcacaacag
     4861 aaggaacaga ttcatacaca acccagtcag ccaatacagc atcaaagatg aatctgtcat
     4921 tccgggatac acctcagtca actacagtca ttacgcgacg aagaatggat gatgtagcag
     4981 caaaaaatat tattgatgtg gttaaaaccg ctcctggatt atatgtcagt acagcagaag
     5041 gttccggaag accgaatttt atgtccagag gatttaatgc taatgtcatg tatgaaggat
     5101 ttagcctgcc gtggaattca tacattccaa gttcacaaac tagttcagct atttttgacc
     5161 gggtggagat agtccgcggg gcaacaggtc ttgttcaggg tgccggagac ccttcagccg
     5221 cgataaatat gatacacaag cgtccgaccc ggcaatatca ggccagcact aacatcggtg
     5281 ccggacggtg gaatgactac cggggtgggg ttgatgtatc aggaccactg aatgacagcg
     5341 cgaccttacg cggaagggca gttgtggatg gcgaaaacag tgagaccttc agggatagtg
     5401 agaaacgcag gaataacgtc atttacggaa ttatggaggc agatctgact gataataccc
     5461 tacttacgat tgggggatat cagcagtatg aatataacaa tcattggtgg tatgacttac
     5521 ctatttctgg taccggacac caccttaatc ttcctcgctc gacgtttaca ggcaatgact
     5581 gggagtttga aagaagtaaa agtaaaactg catttgcaac tcttgagcag aagttcagta
     5641 atagctggaa gctgaaattt tcaacgctgc aaaactggag aaatgctgac ctgttaggga
     5701 cggcaacata ccggcataaa gatacccgac aaagtatgta tcagcaagta tggggatcac
     5761 tgagggaata taattccaaa agctatgacc tgtcgcttaa tggggactat gctttatttg
     5821 gtcgtgttca tcaattcgtg gctggaacaa ctcagcaaaa atacaccgat aaagatacag
     5881 gttatacata ttccccaata tatattgaga atgttaatat atttgatcat ggttcacatt
     5941 cttcgaaaaa acccatgaag atgtcaggtg atgcatccta cgacgtcact gaacaaaaaa
     6001 gcgcctacgc agcaactcat tttctactta gtgataactg gaaaatattg ctgggtggcc
     6061 gtcttgactg gtatgaatat acaagtaaag gtacatccat taatacaggt tataaagtta
     6121 ccagaaatat caccaaatat gcaggttcaa catacaatct tgacgatcat cataccattt
     6181 atgggagcta taccgatata ttcaatccac agtcaagcac cgacctcaat ggtaaagtga
     6241 tcaagcctat tgttggtaag aattatgaga caggtattaa gggtgagtat tttaacggct
     6301 tgcttaatgc ctctctggcg gtatttcagg tagaccagga aaatcgagcc aggctgcttc
     6361 ccgatcagac agggtgtgtt actaatggca atcctcaatg ctatgaggct agcggtaaag
     6421 tacgcacaaa agggatagat ttcgaacttc agggcatggt tacgccactc tgggaaattg
     6481 gggtgggata tacatatgca gatacgcgat atataaaaga tggagatcgt agtaatgaag
     6541 gcaagcgatt caatactgcc gtgtcgccac aaaatttatt taagatttcg agcatgtaca
     6601 cctttgacgg aaaattaaca aactggcgag caggagtaaa cacgtactgg caaagtaaaa
     6661 tatatgctaa cataacagac acaagggatg gcaatccggt tattaataaa caaaaggctt
     6721 attcaacaac tgacattatt attggctata ctccaatgcc acaactggat ttacagctca
     6781 atataactaa tgtctttgat aaggtttatt atacatccat aggtgaatcg attggatatg
     6841 gcacggaaac atatggagaa ccaagaaatg ttaaaattag tgcaacctat agattctaac
     6901 catgcggatt gggtcttctc ctcggatttg cccctataaa tccgtctttt gtggttccgg
     6961 cgtacaaccc cctgtttgcc acttcagttg atggttaatc aaatcatgta gaggatcttc
     7021 ttgagatcct ccatggttcg tcgtaatctt ttgccctgta aacgaaaaaa ccacctgggg
     7081 aggtggtttg atcgaaggtt aagtcagttg gggaactgct taaccgtggt aactggcttt
     7141 cgcagagcac agcaaccaaa tctgtccttc cagtgtagcc ggactttggc gcacacttca
     7201 agagcaaccg cgtgtttagc taaacaaatc ctctgcgaac tcccagttac caatggctgc
     7261 tgccagtggc gtttttgcgt gtctttccgg gttggactca agtgaacagt taccggataa
     7321 ggcgcagcag tcgggctgaa cggggagttc ttgcttacag cccagcttgg agcgaacgac
     7381 ctacaccgag ccgagatacc agtgtgtgag ctatgagaaa gcgccacact tcccgtaagg
     7441 gagaaaggcg gaacaggtat ccggtaaacg gcagggtcgg aacaggagag cgcaagaggg
     7501 agcgacccgc cggaaacggt ggggatcttt aagtcctgtc gggtttcgcc cgtactgtca
     7561 gattcatggt tgagcctcac ggctcccaca gatgcaccga aaaagcgtct gtttatgtga
     7621 attctggcag gagggcgaag cctatggaaa aacgccaccg gcgcggccct gccgttttgc
     7681 ctcacatgtt agtcccctgc ttatccacgg aatctgtggg taactttgcg agagttagca
     7741 gcgcccgccg cagtctcacg gccggagcgt agcgactgag tgagggagga ggcgcaatat
     7801 cccccctccc gcagacggcc accggacgcg cggatgtgac atattgcacc gtgttaccgc
     7861 ctttcccttc cctgccgata aatcattcag ataggtgaag tctgtcggtt ttctgctgaa
     7921 tattttacgt taacctatct ctgttgcttt tttctccttg cggagaaatg caggtcatcc
     7981 ccgctggggc gtggctgact tcaggaggaa atcccctgct tacgctggct ggacgccacc
     8041 gacgcacggt ctttccccct ctttctggct cagctcggct ggacgccggc cacgccagaa
     8101 attcacccgg cccccgtcag gctcacgcct gaccacccac aaaaacccac ggtgctgaac
     8161 gcacctgacg aagcagcaaa gctgctcctg attttgcggg tggtcagccg ctcgctatgg
     8221 cgaactctga cgggggccgg aacaccggaa aagaccgcac tggggtgccg ccttttcctc
     8281 tcacacgctg gggcgtgctc gttgttcctc cggggctgcg ccttttccgc ttggggcgga
     8341 aagaggctgg cctccgtggt gaaagctgaa tgcaatcacc acggacgtga ccgccgccgc
     8401 catgcctcgg ggcatgtccg cggcttgtgc agcaggggct gcacaccacg ccggtaaacc
     8461 cgtcgtctga aggagagaga ttgcatgttt aatacggatt cgcttgcctg gcagtggcat
     8521 atcccggagc tggcccggca gatttacccg tgggtcagct ggctgtacag ggagtattac
     8581 ggtctggccg gggctttcct ggttatcggc ctgtttttcg gtctggctga actctgggcc
     8641 ggacggatgc gttttgtggg gctgagtcat aaggagcgac gggagtatgc cgatcgctat
     8701 aagcgcgata ataaccggac tgcgccattt tcggtgctgg cttcgctgga ttcgcccggg
     8761 cggatggtca gggcacggcg gcatgtctgg aactacgcgt actggctgac cggcgctgcc
     8821 ggtctggccc ttctgggggg gctggttgtc gccgtgttta tcgagagctg gggagaaacc
     8881 gtcctgcgtc cggacctcta cgcgaacgca gattattacc tgctgcagcc ggctaacctg
     8941 ttcgggattg tctggtgtgc cggagggctt gtcgccggca tccttctggc gcggctgctg
     9001 gcatttctgc tgcttgacgg tcattttgcg gccgctgacg aggcggtgaa tgcgaaactg
     9061 aaccaggaga gccggcgcag cagccagcgg accggagaaa tgaccgacgt ccgccacctg
     9121 catttcgggg agccggtacc ggttaacgcg ctggccgatt tttccacaga gcaggcccgg
     9181 aaacagcagg cggtgtttct gggtaaggat gagcagggcc agccggtgct ggtcccgcgt
     9241 gatacctggc gcaagaccaa tattcagatc ctcggcctgc ccgggagcgg caagagcgtg
     9301 atgggcacca acgcgctcat tcgctgcgta cgcgatttcg gggacgcggt ggtgtacttc
     9361 gaccccaaag gggacgcgtg ggcgccgcac gtcttccggg cgcactgccc ggacttcacc
     9421 ctgctggatc tgcggccggg gaaaccggcg cagctgaatc tgtttcgcga tctcgaccag
     9481 tacgccctga agaatctgct ggttgccggg tttaacctga gtgagaccgg cgacgtggcg
     9541 gaccactacc gcatcagcga gcagaaagcg gcgaagctga ttgcggagca gttcccgcag
     9601 ggggcaaaca ttcagcaggt gctggcggcg gcatacgcgc tgccggaggc cctgaaaaag
     9661 gacgtgaagg ggctgatcac caagctggag aacgtggccg acctgagcgt cctgcagacg
     9721 gacagcggca tcgacgtggc ggggataatc aacggcggcg gctgcctgta cgtcatcggc
     9781 tcgatggacg atgaggcggt gatccgggtg cagaagatgc tgtttgcccg ctgcgcgcaa
     9841 atcatcattg cgcgggatga gttccggagg tggccgcacg cgagcatcat gctcgatgag
     9901 attaaatacc tgctgtcgaa gtacgtgctg aacgcgctgg ggacgctgcg cagtcgggac
     9961 tgcaacctgc tgctcgcgca ccagtcgctg ggcgacttcg ggcagtgcgg ccaggatctg
    10021 cccgctgagt ttgtgaaaac cacggtgctg gataacacgc cgatccgctg gttctaccgg
    10081 gcggccagcc aggagtccgc gcagtgggcg gcgggccaga ccggggaaat ccgggtggac
    10141 gtggagcgcc gccgggccag ccgggaggcg gggaacgtgg agcatatcag cggggacagc
    10201 ttcattcaga aggaggcgcg gccgctgttt gacgtgaaca ccctgcagca cctgcctgac
    10261 gggtttgcgg tgatgaccgg gctgggcgtg gcccggatgg cgttcagcag cccgctgcgg
    10321 gttgaacgcc gggaaatccc gctgcagcgc ttcccggtgc tggcgaaaac ggacccgctg
    10381 gcggagtacc agccggaggc cgggcggcag cggccgggtg atgatgattt tgcggggctg
    10441 tactgatggc actggagcga tacaacgtca gccacgcgaa gcggcaggcg cggaacgcgg
    10501 agaaaacccg gctgaccctg cgctggctgc gggaagagct gtgttccacg gcggagctgg
    10561 ttgcgcgacg gctggggatt gcggcggtgc agccggttta ccgcttcctg gacagcctgg
    10621 tggcgaaagg gctgctggtc cgggcgaaat acccggttga cggccgtcag gtcagcgtgt
    10681 ggggactgac gccgcacggg gtggcgttct cgttcgacga ggacgaaccg ctgacggacg
    10741 ttattccgtt tcagccgtca agggtgtcgg cggcgcagct gccgcaccgg ctggccgtgc
    10801 agtccctgcg tctcgccatg gaggcccggg gggcctccgg ctggcggtac ctgcaccgta
    10861 tggccctgaa ggggatgaag gtgccggacg cgctggcgga gctggacggc agaacggtgg
    10921 cgtttgaggt ggagcgcacc gtgaagagcc gcaggcgcta tcaggaggtg gtgtccgggt
    10981 atctgttcaa tcgcaaagcg aacggcatcg atgaaatctg gtacatctgc ccggaccggg
    11041 cgacgcaggt cagggtgcag cgggcgatcc tgtcggtgga tgaaatcgtg aatccacaga
    11101 ccggcgaggc ccgcaaaacg gcggagctgg accgggagcg gctgtttgcg tgctttaaat
    11161 ttatgacaac ggagtgaggg attatggcgc tgtacatggt atttattgaa gacgcggagg
    11221 accgggacgg cgagcgctgc atcatgccga ccagcgagca tcttgaagat atggtggtgc
    11281 tcgcctggca gaccggggcg tatgttttct gttttgtcga ccgggcccag catctggcga
    11341 tgatgaaatc catcgggatg tatgacgagc ggctcaacag cgacgaaaaa gccacgtact
    11401 ttttcaccgg taaaaatccg caatgggaac gggacaaacc cgcaggaatg aagctgtgtg
    11461 attacctcta tcgcaaggtg gagcggttcg ccatcgagaa cggtgtgcag gtggttgatg
    11521 ccgggaagtg ctcaccggag cagattagcg cgatgattga ggtggtcagc gagcggcacg
    11581 gggaaagcgc ggtgaacgag aagctgaaag cggagctgat gcgggaatat aacagccgct
    11641 attttaacgt gccggtgcct gaactgccgg aggacaaacc cgcccgccgg tggtggccgt
    11701 tcggcaaaaa ataaacggca gcaccggcca tgccggtgct gttattcctt cccgagctta
    11761 tcccgcatca cctgccagag tgtttccgca tcctcgtgca gccgctcgca catgtcggcc
    11821 ggggtatcca tatccagctc gttcagtttc tcgagtaaca gcagcgactg gtccttaata
    11881 aatttagcca tattgagggc agttttttcc tgcttagtca tgttttctgt ccttccgggt
    11941 gtggtgtgct tcctgtcggg tatactgtct caaaaccgga ggtgagacaa tggcgtgggt
    12001 gacggtgaga caggcgacgg aactgacggg gaaagcccgg agttccctgt atagggatat
    12061 ggcgaaaggc cgcgtatcat accgtactga agctgatggt ggtcgggtgg tggataccag
    12121 cgaacttatc cgggtgtacg gtgaattaag acagattgag actcacgagc gggacgggtt
    12181 gagactgtcg gatgagactg aaaaaatggc ctccgacgcg ttgatcgcgg agataaaagc
    12241 actcagggag gaggtggccg gactgcggca ggaaatgcag gccatgagac tgctggaaca
    12301 caaaccagag acagcagaga caccggccgg aacatcgcgc cgatggtggc agtggggaaa
    12361 acgctgacgc gctgtgcttg tccaaccggc gacggccacg caatgaattg cgcccccatc
    12421 accggttatc agcgaacggt atggggattc tggcgctggc caaccacggc cagaacccgg
    12481 actttcctgg tctggtcatc aacatcatag aggacatgct gtcccatcag actgatccgg
    12541 cgaacgtcct cgccatagcg tgagtccact tcatataggc gcgggaagtc ggccagtttg
    12601 tccgctgcag cgagaactcg atcggtaacg ttctgcgcat cccacaggga tgaattttcc
    12661 gcaatgtagt caaacaatgc tgtcacatcc tcgatggctc cctgcttcca ttccacctca
    12721 tacggcatcg cgtagttcct gatagcggcc atgcagtctc tggcggagtt gttccgtggt
    12781 catgcccggg cgcgtgtcag cgcgggcggc ggtcacttta gcgcgaacct gatcttcata
    12841 ttctgcctgg gccagttctt cgttagccag gcgctgcaac agtgcagctt tgtccgggcc
    12901 accttcaggc agtatgcggg gcagtctctc ggccagttcc cgcaggaaat tggcgttttc
    12961 atagtgtgta ctgttgctca ttgtggagcc tcccgggctg atacgtcgat atgaaggagt
    13021 ttagcagggg gcggtctgaa agaatatgct cgtgtcagtc aggctgatga agacgaaagc
    13081 tggtaaaaaa gggcttacga cacccatttt acgtcaaact gcacgacatg cagttgcgtg
    13141 catagccatg cagcgggtta aaatttatca ggcgcgtttc cggcggtttt ccgggtggtt
    13201 tgttgccggt tttatcccgt agccgccgga aatgccctca gaccgtctga gcggtgcgcg
    13261 taatgcgacg ttatggtaaa tcatgtgatt aatggtagtg ataatcatta tcacttttgc
    13321 tatattcttg tttcttttat tgtaaggaaa tgtaagtatg gcaatcacga ttaaatccgc
    13381 cgttaatgtc cgtagcagag tattaatata ctctttacta ctgtttactg gttcagcgta
    13441 tgcggctgat atagctgaat caacattcct gactcgtgat atcggcaatg gtctgtatga
    13501 aatgtctttt gatggcaaaa ataatagtct ctgggcagca tcatcgtctt cattcgacag
    13561 agataagggc cacggaattg tttatcagtt agaaccatcc actctgaaaa caaaatctgc
    13621 cgttaaaatc gcacgtcttg ggtttgccac agcactggat gaggaacatg agcgacttta
    13681 tatcggcaat actctggacg gctcagtgac ggtcattgat actctaaccg gaaaagaact
    13741 ttcagtaatt ccgttaactg agggacagga tgaggctcat ttcagaccga ccagagaaat
    13801 ggtcattgac aaaaaaaatc agcgtcttta tgtctccagc gccgcagata aaggggctct
    13861 gtgggttatt gacatggctg tcgggaagaa aattaaaacc attgatggac tggggcacgc
    13921 tgttactgga attgcgttaa ataaaaatgg ggataatatt tatctggtta acggggatgg
    13981 tgagattatt aacctggatg ccagtagcta tgaaataaaa aaacggtttg ttgtagagcc
    14041 tgagaaaaaa cactttttcc ttaatgtaag tctggatgaa aaaaacggac gtgcatttat
    14101 taccgacccg gatattcccg gggtgctggt tgttgatgta aactcgggaa aaatactaca
    14161 cagaattgat gttataaatt cactggcgat tttatttaat cctttacgga acgaaatcta
    14221 tatcacgcac cgtaatgcaa aacaggtcag cattgtggac agtaattctt attacgtaaa
    14281 aacaacgata aaaacccgcc tgatgccaaa cagtctgtct ttatcacatg acggtgaaaa
    14341 tctgtacgtt agtgtaaaac aagaaaaaaa gagatgagta ctatgaagga ttacatactc
    14401 aaaatcgaat tatctaaaat tgctatggag ccagaagaat gaataaatat ttagggctga
    14461 gcatagtata tatgatgtat acatcatctg ttatggctga tgattctggc gcagttagta
    14521 aagataaaaa tatttcacca gaagaaacat taattgttca tgggaccgct gtttctgaaa
    14581 gcacaacaga aggaacagat tcatacacaa cccagtcagc caatacagca tcaaagatga
    14641 atctgtcatt ccgggataca cctcagtcaa ctacagtcat tacgcgacga agaatggatg
    14701 atgtagcagc aaaaaatatt attgatgtgg ttaaaaccgc tcctggatta tatgtcagta
    14761 cagcagaagg ttccggaaga ccgaatttta tgtccagagg atttaatgct aatgtcatgt
    14821 atgaaggatt tagcctgccg tggaattcat acattccaag ttcacaaact agttcagcta
    14881 tttttgaccg ggtggagata gtccgcgggg caacaggtct tgttcagggt gccggagacc
    14941 cttcagccgc gataaatatg atacacaagc gtccgacccg gcaatatcag gccagcacta
    15001 acatcggtgc cggacggtgg aatgactacc ggggtggggt tgatgtatca ggaccactga
    15061 atgacagcgc gaccttacgc ggaagggcag ttgtggatgg cgaaaacagt gagaccttca
    15121 gggatagtga gaaacgcagg aataacgtca tttacggaat tatggaggca gatctgactg
    15181 ataataccct acttacgatt gggggatatc agcagtatga atataacaat cattggtggt
    15241 atgacttacc tatttctggt accggacacc accttaatct tcctcgctcg acgtttacag
    15301 gcaatgactg ggagtttgaa agaagtaaaa gtaaaactgc atttgcaact cttgagcaga
    15361 agttcagtaa tagctggaag ctgaaatttt caacgctgca aaactggaga aatgctgacc
    15421 tgttagggac ggcaacatac cggcataaag atacccgaca aagtatgtat cagcaagtat
    15481 ggggatcact gagggaatat aattccaaaa gctatgacct gtcgcttaat ggggactatg
    15541 ctttatttgg tcgtgttcat caattcgtgg ctggaacaac tcagcaaaaa tacaccgata
    15601 aagatacagg ttatacatat tccccaatat atattgagaa tgttaatata tttgatcatg
    15661 gttcacattc ttcgaaaaaa cccatgaaga tgtcaggtga tgcatcctac gacgtcactg
    15721 aacaaaaaag cgcctacgca gcaactcatt ttctacttag tgataactgg aaaatattgc
    15781 tgggtggccg tcttgactgg tatgaatata caagtaaagg tacatccatt aatacaggtt
    15841 ataaagttac cagaaatatc accaaatatg caggttcaac atacaatctt gacgatcatc
    15901 ataccattta tgggagctat accgatatat tcaatccaca gtcaagcacc gacctcaatg
    15961 gtaaagtgat caagcctatt gttggtaaga attatgagac aggtattaag ggtgagtatt
    16021 ttaacggctt gcttaatgcc tctctggcgg tatttcaggt agaccaggaa aatcgagcca
    16081 ggctgcttcc cgatcagaca gggtgtgtta ctaatggcaa tcctcaatgc tatgaggcta
    16141 gcggtaaagt acgcacaaaa gggatagatt tcgaacttca gggcatggtt acgccactct
    16201 gggaaattgg ggtgggatat acatatgcag atacgcgata tataaaagat ggagatcgta
    16261 gtaatgaagg caagcgattc aatactgccg tgtcgccaca aaatttattt aagatttcga
    16321 gcatgtacac ctttgacgga aaattaacaa actggcgagc aggagtaaac acgtactggc
    16381 aaagtaaaat atatgctaac ataacagaca caagggatgg caatccggtt attaataaac
    16441 aaaaggctta ttcaacaact gacattatta ttggctatac tccaatgcca caactggatt
    16501 tacagctcaa tataactaat gtctttgata aggtttatta tacatccata ggtgaatcga
    16561 ttggatatgg cacggaaaca tatggagaac caagaaatgt taaaattagt gcaacctata
    16621 gattctaacc atgcggattg ggtcttctcc tcggatttgc ccctataaat ccgtcttttg
    16681 tggttccggc gtacaacccc ctgtttgcca cttcagttga tggttaatca aatcatgtag
    16741 aggatcttct tgagatcctc catggttcgt cgtaatcttt tgccctgtaa acgaaaaaac
    16801 cacctgggga ggtggtttga tcgaaggtta agtcagttgg ggaactgctt aaccgtggta
    16861 actggctttc gcagagcaca gcaaccaaat ctgtccttcc agtgtagccg gactttggcg
    16921 cacacttcaa gagcaaccgc gtgtttagct aaacaaatcc tctgcgaact cccagttacc
    16981 aatggctgct gccagtggcg tttttgcgtg tctttccggg ttggactcaa gtgaacagtt
    17041 accggataag gcgcagcagt cgggctgaac ggggagttct tgcttacagc ccagcttgga
    17101 gcgaacgacc tacaccgagc cgagatacca gtgtgtgagc tatgagaaag cgccacactt
    17161 cccgtaaggg agaaaggcgg aacaggtatc cggtaaacgg cagggtcgga acaggagagc
    17221 gcaagaggga gcgacccgcc ggaaacggtg gggatcttta agtcctgtcg ggtttcgccc
    17281 gtactgtcag attcatggtt gagcctcacg gctcccacag atgcaccgaa aaagcgtctg
    17341 tttatgtgaa ttctggcagg agggcgaagc ctatggaaaa acgccaccgg cgcggccctg
    17401 ccgttttgcc tcacatgtta gtcccctgct tatccacgga atctgtgggt aactttgcga
    17461 gagttagcag cgcccgccgc agtctcacgg ccggagcgta gcgactgagt gagggaggag
    17521 gcgcaatatc ccccctcccg cagacggcca ccggacgcgc ggatgtgaca tattgcaccg
    17581 tgttaccgcc tttcccttcc ctgccgataa atcattcaga taggtgaagt ctgtcggttt
    17641 tctgctgaat attttacgtt aacctatctc tgttgctttt ttctccttgc ggagaaatgc
    17701 aggtcatccc cgctggggcg tggctgactt caggaggaaa tcccctgctt acgctggctg
    17761 gacgccaccg acgcacggtc tttccccctc tttctggctc agctcggctg gacgccggcc
    17821 acgccagaaa ttcacccggc ccccgtcagg ctcacgcctg accacccaca aaaacccacg
    17881 gtgctgaacg cacctgacga agcagcaaag ctgctcctga ttttgcgggt ggtcagccgc
    17941 tcgctatggc gaactctgac gggggccgga acaccggaaa agaccgcact ggggtgccgc
    18001 cttttcctct cacacgctgg ggcgtgctcg ttgttcctcc ggggctgcgc cttttccgct
    18061 tggggcggaa agaggctggc ctccgtggtg aaagctgaat gcaatcacca cggacgtgac
    18121 cgccgccgcc atgcctcggg gcatgtccgc ggcttgtgca gcaggggctg cacaccacgc
    18181 cggtaaaccc gtcgtctgaa ggagagagat tgcatgttta atacggattc gcttgcctgg
    18241 cagtggcata tcccggagct ggcccggcag atttacccgt gggtcagctg gctgtacagg
    18301 gagtattacg gtctggccgg ggctttcctg gttatcggcc tgtttttcgg tctggctgaa
    18361 ctctgggccg gacggatgcg ttttgtgggg ctgagtcata aggagcgacg ggagtatgcc
    18421 gatcgctata agcgcgataa taaccggact gcgccatttt cggtgctggc ttcgctggat
    18481 tcgcccgggc ggatggtcag ggcacggcgg catgtctgga actacgcgta ctggctgacc
    18541 ggcgctgccg gtctggccct tctggggggg ctggttgtcg ccgtgtttat cgagagctgg
    18601 ggagaaaccg tcctgcgtcc ggacctctac gcgaacgcag attattacct gctgcagccg
    18661 gctaacctgt tcgggattgt ctggtgtgcc ggagggcttg tcgccggcat ccttctggcg
    18721 cggctgctgg catttctgct gcttgacggt cattttgcgg ccgctgacga ggcggtgaat
    18781 gcgaaactga accaggagag ccggcgcagc agccagcgga ccggagaaat gaccgacgtc
    18841 cgccacctgc atttcgggga gccggtaccg gttaacgcgc tggccgattt ttccacagag
    18901 caggcccgga aacagcaggc ggtgtttctg ggtaaggatg agcagggcca gccggtgctg
    18961 gtcccgcgtg atacctggcg caagaccaat attcagatcc tcggcctgcc cgggagcggc
    19021 aagagcgtga tgggcaccaa cgcgctcatt cgctgcgtac gcgatttcgg ggacgcggtg
    19081 gtgtacttcg accccaaagg ggacgcgtgg gcgccgcacg tcttccgggc gcactgcccg
    19141 gacttcaccc tgctggatct gcggccgggg aaaccggcgc agctgaatct gtttcgcgat
    19201 ctcgaccagt acgccctgaa gaatctgctg gttgccgggt ttaacctgag tgagaccggc
    19261 gacgtggcgg accactaccg catcagcgag cagaaagcgg cgaagctgat tgcggagcag
    19321 ttcccgcagg gggcaaacat tcagcaggtg ctggcggcgg catacgcgct gccggaggcc
    19381 ctgaaaaagg acgtgaaggg gctgatcacc aagctggaga acgtggccga cctgagcgtc
    19441 ctgcagacgg acagcggc
//
