LOCUS       NZ_CP129375            28674 bp    DNA     circular CON 19-JUL-2023
DEFINITION  Staphylococcus epidermidis strain CSMH-411EB plasmid pCSME411-1,
            complete sequence.
ACCESSION   NZ_CP129375
VERSION     NZ_CP129375.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36269258
            Assembly: GCF_030435955.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28674)
  AUTHORS   Lee,G.Y. and Yang,S.-J.
  TITLE     Genome sequence of a S. epidermidis isolate recovered from a chicken
            meat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28674)
  AUTHORS   Lee,G.Y. and Yang,S.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2023) Department of veterinary microbiology, Seoul
            National University, 1, Gwanak-ro, Gwanak-gu, Seoul 08826, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Prokka v. v1.14.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 552.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina iSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/14/2023 15:52:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,412
            CDSs (total)                      :: 2,328
            Genes (coding)                    :: 2,267
            CDSs (with protein)               :: 2,267
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 38 of 61
            Pseudo Genes (incomplete)         :: 32 of 61
            Pseudo Genes (internal stop)      :: 25 of 61
            Pseudo Genes (multiple problems)  :: 24 of 61
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP129375.1.
            Bacteria and source DNA available from Seoul National University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28674
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="CSMH-411EB"
                     /isolation_source="Chicken meats"
                     /db_xref="taxon:1282"
                     /plasmid="pCSME411-1"
                     /geo_loc_name="South Korea: Gyeonggi"
                     /lat_lon="37.2 N 126.9 E"
                     /collection_date="2019-06-01"
                     /collected_by="Chung-Ang University"
     gene            1..972
                     /locus_tag="QYE82_RS11720"
     CDS             1..972
                     /locus_tag="QYE82_RS11720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_002485957.1"
                     /translation="MSNFNIKEIQKEKFYQLPKVFFTNPKYTNLSNDAKITWSILRDRL
                     DLSIRNNWIDKNGDIFFIYTNEKLKSILNISSPNKLSKIKKELTQADLFNQIRVGLNKP
                     NKLYIKKPEVTEADVYYISQQENDIEQRDNTDVSLSYVQKYDNDTSRNINNIRHEVSKE
                     YTSDTDLNETEYIKTENNDTNDLNDTSDIVSKNYHSNHTNHQQTEFNNNALKFQALEEL
                     PTQIKTYLSNFEIKDIRIIKSVLLKGKKSFNNAHDTYYRLEDVEFELVSVLKRFKAMLI
                     QKNENVEAMQGYLMQSIKAELEEIHALNMRRQNIPKYNIFNQ"
                     /name="replication initiator protein A"
     gene            complement(1609..1935)
                     /locus_tag="QYE82_RS11725"
     CDS             complement(1609..1935)
                     /locus_tag="QYE82_RS11725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="WP_002485949.1"
                     /translation="MPMFNKVLVKDIEKSEKWYEKTLGFKSVFKFRNDKNEVLMNHLRL
                     EKHQDLILIVQTDFEVGNSIYLNILVKDIEDKSQHISSKFIVTQLEDQPWNAKEMTIKD
                     PDGH"
                     /name="VOC family protein"
     gene            complement(2057..2620)
                     /locus_tag="QYE82_RS11730"
     CDS             complement(2057..2620)
                     /locus_tag="QYE82_RS11730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="WP_002485953.1"
                     /translation="MSKDKRSNKWAFLIYEESSPSNYRDILEQMHIPYILSPWHNQDID
                     HSTGEIKKSHKHGALFFDSLKSYSQVSELLQQHLNTPSHIEIIMSPKGMFDYFIHASNT
                     DKTPYDINDIESGCGFDLNQFLLDQGQSEIFNKIIDIIENQDFTEFQSLVMYARQHHPS
                     YLHLIIQRTYFFAKYLDSRRHMFN"
                     /name="replication protein"
     gene            complement(2744..3346)
                     /locus_tag="QYE82_RS11735"
     CDS             complement(2744..3346)
                     /locus_tag="QYE82_RS11735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001233000.1"
                     /translation="MRKTYFMRVYDIIIYLFLFAILTVMVSKLFVLLNFIVSQIDIIDT
                     RNVTHYITIISNGVYQLTFYLLVLALMLIVIDLMIRLLKDQLTNHIKSVYHTMVLRHYL
                     KQDVDTDTTQDWQNNGKSKTNSVQQYFNKMVGKSLVDVRQNEVRVAIKIPRKQQAHDIL
                     KKIEPQIHEEITHMHPNYYFSKPQRHHRYLWFAGHKR"
                     /name="hypothetical protein"
     gene            complement(3346..4422)
                     /locus_tag="QYE82_RS11740"
     CDS             complement(3346..4422)
                     /locus_tag="QYE82_RS11740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002272712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000125496.1"
                     /translation="MTAKELEQYLLQSLNMALGSMMQGETSYTNSFTCKVTEEGFYFLP
                     RLPAGYIVDDDLYQKIFLIASAALYPKFTLLKQNSAYFVPMDTDDIHTQRALFFPWQQG
                     ISERLVISDLDRFTSSLTNQQIPIMKQLTLNYQNITSIAIAGNSGSGKSYMLTYLLSVL
                     KPISELIIVDPKFDTPSRWARIHDITVIHPHQNRSKSDFLSEINENLSHCLQVIQQRQT
                     ILYDDPDYQFDHLTIVIDEVLALAEGVNKTIKDAFFSLLSQIALLGRATKVHLLLVSQR
                     FDHQTIPVSVREQLNVLIQIGNINKKTTQFLFPDLDPEGIVIPIGKGTGLIQVIDSESP
                     YQVLPLLCPTYYTKAGVL"
                     /name="hypothetical protein"
     gene            complement(4422..4736)
                     /locus_tag="QYE82_RS11745"
     CDS             complement(4422..4736)
                     /locus_tag="QYE82_RS11745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_025174876.1"
                     /translation="MQSNFKKGGYSTEIASNYIDNKKPIYSLSTELYPQQRFENNQPTG
                     EIIAYKAWFVQEGLPPFTVKFENEVTLPNYMSVITFDHLEACEVRYDVYFKASDLKEVK
                     "
                     /name="hypothetical protein"
     gene            4891..6090
                     /locus_tag="QYE82_RS11750"
     CDS             4891..6090
                     /locus_tag="QYE82_RS11750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002488420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001831368.1"
                     /translation="MIIINNKGINDLDFNYWMNNQLTDDNIEEILEGSDLSMEQEIFKS
                     NYKKFLEIDGKKERWYSLEEAAYIINGNYFSIYEEDSKKRSVTTDYVKNKSNDILNNIE
                     NGTNQNWNKYHYPQKRKFAFKKVKYVNEDMIDEILRDDVTKPEKIKRGNISIEELLPNQ
                     NRIAKYIRQNENIHNKSIMIDYLNQLSDTLAKSLDDVRYFSNKLSLFKSVIKDSREIAQ
                     NIHRDHDIDNKEKYELLKKEYSNFLENCIRFSNEYLDILDIKNIFNIFDTKKIVLNLSY
                     YTKMWEVPDINNEQPINNNLQKFVDLKKKKYLNNVHWSKNKILKQLNEIEVKPVTLKDG
                     TSETERVAEWMYRNKTKVVYEIINKEFDDVYDLLNGMLKSEYTELMGYMRIWHNLSKNL
                     "
                     /name="hypothetical protein"
     gene            6132..6947
                     /locus_tag="QYE82_RS11755"
     CDS             6132..6947
                     /locus_tag="QYE82_RS11755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001832799.1"
                     /translation="MYFKNMDFLIDLYKNFNEVGIFAVIYIIYALIQILSQNILYKRQK
                     MERVKTLIINIILYIFITLVALMYLLAMIFYSLSAYPKEEVIKYITDWDKISLPAILLV
                     LYSLLFPIFIFPFVGKRRRKNYFAENVNNCIIEREIIDRVSINGRDKLILKDALGYQTE
                     KDITGIKDLKISTSQKKSWLTLEDIKIATMSLRDKQLLLKMIIGLIIFGVPTGYFVWNF
                     ISVVDDWDRIMHANDIFMYMGLFTLPLMVTVELYVVAFIITKNLFKKKK"
                     /name="hypothetical protein"
     gene            7566..8048
                     /locus_tag="QYE82_RS11760"
     CDS             7566..8048
                     /locus_tag="QYE82_RS11760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="WP_001831392.1"
                     /translation="MKLYYVDEDYINELRNVDERVLLNKSTRPYLGVVLSINDLNYFVP
                     LSSPKENKKLNNQLSIKLFEVNNIQNRLGYLLFLNMIPVPDKYLSKIDMQYIKEQDLEY
                     YNLLTNQLIFIRQENQRIVNKAQKVYKNAVIKKVSFFESMCVDYLALERYVKDLKQ"
                     /name="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
     gene            complement(8316..8843)
                     /locus_tag="QYE82_RS11765"
     CDS             complement(8316..8843)
                     /locus_tag="QYE82_RS11765"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_001831394.1"
                     /translation="MIKFEYFEEKDFDLLINWINSPELLVKWAGTDFNYPLDEEQLKEY
                     IKDTNKENSSKIIYKVIIEENNSKKIIGHIALNNIDFKNCSATLSKVLVGDPQMRGQGL
                     GPKIIKKLLKKAFEDLGLHRIELGVFAFNKSAIKSYKKIGFIKEGEKRDFRKLNGEYYN
                     LWQMSMLESEWS"
                     /name="GNAT family protein"
     gene            complement(9036..9692)
                     /locus_tag="QYE82_RS11770"
     CDS             complement(9036..9692)
                     /locus_tag="QYE82_RS11770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001831384.1"
                     /translation="MNHNHEYHSNKPEIKANVVYRDGNIEITLEDEFNNAPLLDTMHEK
                     EMHFVLVSNDMEKYYHLHPQKKHEGLFIINQQLEPGTYQAFVDVTPKNHVYSVHPIELQ
                     IGDKITSTTSLNSDKNWVKVNKGVHVTLNSISAKEDEHVPLTFNTELTPQPYLGALGHV
                     IIFDEQLTDYIHVHPESPDSTTFYAHFPKKGMYKIWAEFKFNDEVHRFTYNIKVA"
                     /name="hypothetical protein"
     gene            complement(9756..9965)
                     /gene="copZ"
                     /locus_tag="QYE82_RS11775"
     CDS             complement(9756..9965)
                     /gene="copZ"
                     /locus_tag="QYE82_RS11775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831373.1"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="WP_001831373.1"
                     /translation="MTNEVINVEGMSCDHCKHSIEKALNGLDGVTSSEVSLANGNVEVE
                     FDENQVAFNDFKEAIEDQGYDVIK"
                     /name="copZ"
     gene            complement(9999..12386)
                     /locus_tag="QYE82_RS11780"
     CDS             complement(9999..12386)
                     /locus_tag="QYE82_RS11780"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485948.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0019829 - ATPase-coupled monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_001832797.1"
                     /translation="MSENIKKTSLGITGMTCAACSNKVEKNLNKLDEVNANVNPSTEKA
                     TIEYNPNVTSLEDIANTIQKTGYGVLTEKVDLDVMGMTCAACSNKIEKVLNRISGVNKA
                     TVNLTTESATVEYNPDMTSVDEFQQRIKNLGYEAQPKKEASEKSSQKEKQLKRQLIKLV
                     VSAVLAAPLLMTMFVHLFGIQIPHIFMNPWFQFVLATPVQFVIGWQFYVGAYKNLRNGS
                     ANMDVLVALGTSAAFFYSIYESIKWLINTNYEPHLYFETSAVLITLILFGKYLEARAKT
                     QTTNALSKLLNLQAKEARILRNGEETMVPLSEVKEGDYLVIKPGEKIPVDGKIIKGMTS
                     IDESMLTGESIPVEKMQNDNVIGSTMNKNGAITVEATKVGKDTALASIVKVVEEAQGSK
                     APIQRLADIISGYFVPIVVGIAIFTFIIWISLVQPGQFEPALVAAIAVLVIACPCALGL
                     ATPTSIMVGTGKAAENGILFKGGEHIEGTHAINTVVLDKTGTITNGTPEVTDFSGDDQT
                     LQLLASAEKGSEHPLAEAIVSYAKEKSLEFLEVDHFEAIPGRGINATIDGKELFVGNRK
                     LMSEKGIQTNEAETNLAQFEKEGKTAMLISVDNELRGVVAVADTVKDTAQQAIQKLHEL
                     GIEVAMLTGDNKRTAQAIAKQVGIDTIIAEVLPEEKASKVAEIQSEGKKVAMVGDGVND
                     APALVKADIGIAIGTGTEVAIEAADITILGGDLLLIPKAIKASKSTIRNIRQNLFWAFG
                     YNVAGIPIAAIGLLAPWVAGAAMALSSVSVVTNALRLKRMKL"
                     /name="heavy metal translocating P-type ATPase"
     gene            complement(12401..12676)
                     /locus_tag="QYE82_RS11785"
     CDS             complement(12401..12676)
                     /locus_tag="QYE82_RS11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831396.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="WP_001831396.1"
                     /translation="MNTTTVKNNDALLNRLKRLEGQMRGLQSMIAEDRYCIDVLVQITA
                     IQSALKQVGFIVTEDHISNCVSEGIKNGNGEESIKELMVVLKQFSK"
                     /name="metal-sensing transcriptional repressor"
     gene            12851..13126
                     /locus_tag="QYE82_RS11790"
     CDS             12851..13126
                     /locus_tag="QYE82_RS11790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489264.1"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="WP_001831374.1"
                     /translation="MDKNIQLELYTRPTCSDCQESKRYLNSQEISYSHKDVSQNLDLEE
                     EMKKISGNRIVPLFVFYKKIFWGKKKLFKYYVGFENNKKDILNILE"
                     /name="glutaredoxin family protein"
     gene            complement(13167..14108)
                     /locus_tag="QYE82_RS11795"
     CDS             complement(13167..14108)
                     /locus_tag="QYE82_RS11795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449936.1"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_001831389.1"
                     /translation="MENDHNHNHTHGANKKTLLISFIIITSYMIVEGLGGFFTNSLALI
                     SDAGHMLSDSISLGIALIAFTLGAKQANTNKTFGYKRFEILAAVLNGITLMLIAIYIFY
                     EAIERFKNPPEVASTGMLIIALVGLFINIIVAWIMLRGSDVEENLNMRGAYLHVISDML
                     GSIGAVIAALLIIFFRWGWADPLASVIVAILVLRSGFYVTKSSLHVLMEGAPSNINTKD
                     IIKTIKKFKEVKNIHDFHVWSVTSGLNALSCHIVVEDTMTITENEFLLKRIEHELNHQN
                     IQHVTIQTETSNNNHSEKLFCIVKEEDSQHHH"
                     /name="cation diffusion facilitator family transporter"
     gene            complement(14471..14872)
                     /locus_tag="QYE82_RS11800"
     CDS             complement(14471..14872)
                     /locus_tag="QYE82_RS11800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_008797778.1"
                     /translation="MKVNKVGNKSLIDDNTIDYLKTILNKKTTKESTKFDEKSTNKTES
                     LNNQYSSYIDKYIEHLESEIRQKNRQIDDLTIALKQEQSLNLNSQNILSNTKKIETDNI
                     DSKEDIITPKASKKNEQKQSIFSKLFKKK"
                     /name="hypothetical protein"
     gene            complement(14988..15662)
                     /locus_tag="QYE82_RS11805"
     CDS             complement(14988..15662)
                     /locus_tag="QYE82_RS11805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_096807895.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIKCIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(15729..16574)
                     /gene="blaZ"
                     /locus_tag="QYE82_RS11810"
     ARG             complement(15733..16574)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16681..18438
                     /gene="blaR1"
                     /locus_tag="QYE82_RS11815"
     ARG             16682..18435
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            18428..18808
                     /gene="blaI"
                     /locus_tag="QYE82_RS11820"
     ARG             18429..18805
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            19072..19650
                     /locus_tag="QYE82_RS11825"
     CDS             19072..19650
                     /locus_tag="QYE82_RS11825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001829991.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNQYGCEKIFSDHISGSRSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRMAARARGRYGGRPEKLNKQDLTLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNKLNNQENKDK"
                     /name="recombinase family protein"
     gene            19780..20388
                     /locus_tag="QYE82_RS11830"
     CDS             19780..20388
                     /locus_tag="QYE82_RS11830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_096807894.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFGAEKIFTEKQSGKSIENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSANAKDPQKRI
                     IYHRVVKMLEEGQAISKIAKEVNITRQTIYRIKHDNNLD"
                     /name="recombinase family protein"
     gene            <20394..20731
                     /locus_tag="QYE82_RS11835"
                     /pseudo=""
     CDS             <20394..20731
                     /locus_tag="QYE82_RS11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500394.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /name="ArsB/NhaD family transporter"
     gene            20724..21125
                     /gene="arsC"
                     /locus_tag="QYE82_RS11840"
     CDS             20724..21125
                     /gene="arsC"
                     /locus_tag="QYE82_RS11840"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468543.1"
                     /GO_function="GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="WP_096807893.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKQILGEDWHVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLINSDILKESDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRNEIGNTIKDFSKNIK"
                     /name="arsC"
     gene            21250..21552
                     /locus_tag="QYE82_RS11845"
     CDS             21250..21552
                     /locus_tag="QYE82_RS11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467792.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_096807892.1"
                     /translation="MKSKIHRKLFLGFVYIHILHHASEDKIYGAWMIKELYEHGYHMSP
                     GTLYPILHTLENDNLLKSATKTVNGKNRKYYSITPKGEKFLKESREKLKELTNEI"
                     /name="PadR family transcriptional regulator"
     gene            21571..>21873
                     /locus_tag="QYE82_RS11850"
                     /pseudo=""
     CDS             21571..>21873
                     /locus_tag="QYE82_RS11850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467791.1"
                     /GO_function="GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /name="chromate transporter"
     gene            21981..23153
                     /locus_tag="QYE82_RS11855"
     CDS             21981..23153
                     /locus_tag="QYE82_RS11855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            complement(23283..24722)
                     /gene="aph(2'')-Ia"
                     /locus_tag="QYE82_RS11860"
     CDS             complement(23283..24722)
                     /gene="aph(2'')-Ia"
                     /locus_tag="QYE82_RS11860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(24723..25115)
                     /locus_tag="QYE82_RS11865"
     CDS             complement(24723..25115)
                     /locus_tag="QYE82_RS11865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(25172..26344)
                     /locus_tag="QYE82_RS11870"
     CDS             complement(25172..26344)
                     /locus_tag="QYE82_RS11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            26400..27299
                     /gene="chrA"
                     /locus_tag="QYE82_RS11875"
     CDS             26400..27299
                     /gene="chrA"
                     /locus_tag="QYE82_RS11875"
                     /inference="COORDINATES: protein motif:HMM:TIGR00937.1"
                     /GO_function="GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="WP_301560577.1"
                     /translation="MLYGLFTFTQLYGLYLSFTWMQGLKLVAVAIVGQAIIGMGKKLTN
                     TKTTIALALFVLILSLVINNLYIQVIALSITGVYGLIFLKQTSTDKSKIKNKSFKLPKK
                     LGFVSLSLFFLLLTVLPIASSMTNNLWLKMFDSFYRSGSLVFGGGHVVLPLLKNEFVPS
                     GLISPDNFITGYAAAQAVPGPLFTFASYIGMSIEGIGGAILATFAIFLPAFLLLFGILP
                     FWDNIKSNIYAEGFLKGISAGVVGILIAAFYNPIWTSTIKSELDFTLASSLFILLMYFR
                     FPSWAIVLIGIILGILFY"
                     /name="chrA"
     gene            complement(27491..28180)
                     /locus_tag="QYE82_RS11880"
     CDS             complement(27491..28180)
                     /locus_tag="QYE82_RS11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002485951.1"
                     /translation="MKSMKEIADELNVTKMTVYNNAKKANVKFQKVDNVNYLASEDEII
                     VVNRIRKNQNKHNDFENEKKEEVKTNSNNLVKDETIKHLYNQLDIYKEQSNRDKEQINT
                     LNRLLENQQILALESNKKIQKLENQLEEERQLNYSFDIEKTNNKQNVNMQEAVFTEGNQ
                     NRAQQQEKKKPTETEHKDISEKNKNKSIKEDELLKDAKLTEAIKSEPDDREEESPKKGF
                     WSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             complement(23287..24722)
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(23284..24722)
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(15730..16574)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.02"
                     /coverage="100.0"
     Typing          2..972
                     /name="rep_cluster_1110"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.571"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2055..2623)
                     /name="rep_cluster_2341"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.266"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atgtccaact ttaatattaa agaaattcaa aaagaaaagt tttaccaatt acccaaagta
       61 ttttttacga atcctaagta tactaattta tccaatgatg caaaaatcac ttggtctata
      121 ctaagagatc gtttagattt atctataaga aataattgga tagataagaa tggagatata
      181 ttttttattt acaccaatga aaaacttaaa tctattttaa atatcagtag tcccaataaa
      241 ttatctaaaa ttaaaaaaga attaacacaa gctgatttat ttaatcaaat acgagtaggg
      301 ttgaataaac ctaataaatt atatattaaa aaaccagaag taacagaagc tgatgtatat
      361 tatatttcac aacaagaaaa cgatatagaa caacgagata acacggacgt atcattatca
      421 tacgtccaga aatatgataa tgatacatca agaaatatta ataacatacg tcatgaagta
      481 tcaaaagaat acacaagtga tactgatctt aatgaaactg aatatataaa gactgagaat
      541 aatgatacga atgatttgaa tgatacatct gacatagttt ctaaaaatta tcattcgaat
      601 catacaaatc atcaacaaac tgaatttaat aataatgctc taaaattcca agcgcttgaa
      661 gaattaccta cacaaatcaa gacttattta agtaattttg aaattaaaga catccgtatt
      721 attaaaagtg ttttactcaa agggaaaaag tcatttaata atgcacatga tacatattat
      781 cgtttagagg acgttgaatt tgaacttgtg agtgttttaa aacgttttaa agccatgttg
      841 atacaaaaaa atgaaaatgt tgaagcgatg caaggctatt taatgcaatc aattaaagct
      901 gaacttgaag aaatacatgc attaaatatg cgtcgccaaa atatacctaa atacaatatc
      961 tttaatcaat aattcaaata agcttctaac aagtaaaata attttaaaat atttgataat
     1021 gtcaggttct attttgaaat tgttgacata actggattat tcaaatttga ttttatatgt
     1081 aaataatatc taaaaattcg ccattcgtta gaaataaaca acaaatgtaa cggtttaaat
     1141 ttataaatga tagggagttc caatcaaatt agcgaaacat gagaaatggt tttgaattat
     1201 tacgagtact atgtataaaa gatacgaata catgtatatt aagtgacatg agccaatcag
     1261 tttatatatc acataaaata catgtaaagt acgtaataaa tgtcatatgt atatactctt
     1321 atttgtctcg tatttgtgtt ttaaagggca aaattaaatg gatagaaaaa actatgtgag
     1381 attagaattt gctctaaata cccctttaaa atgcaaaata atgatattta aaattcggaa
     1441 aaataaaaag atcctagaga aatttctaga atctttattt ggcataatga ctcatagata
     1501 tttatttttg tattatcaat aaaggtttat gcctcaataa tttttcgaag tatgtttcat
     1561 taatttttca aaatcagtat cgctaatatt tgattgagta agtgtgattt agtggccgtc
     1621 tggatctttg attgtcattt ctttagcgtt ccatggttgg tcttctaatt gagttactat
     1681 aaattttgat gagatatgtt gtgatttatc ttcgatatct ttgactaaga tattgagata
     1741 tattgaattg ccaacttcaa aatctgtttg aacaattaag attaaatctt gatgtttttc
     1801 tagtcttaaa tgattcataa gcacttcatt tttatcattt ctaaatttaa aaacactttt
     1861 aaagccaagt gttttttcat accatttttc tgatttctca atgtctttaa ctaggacttt
     1921 gttaaacata ggcatttggt aaaactctat cgttttcacc tctttttatt aattgtaatg
     1981 tattacgctg cgttaatgtc aagaaagagt aagctgagaa acaggtttct tctcgtcttg
     2041 atacatgata tccattttaa ttaaacatgt gacgccttga atccaaatat tttgcgaaaa
     2101 aatatgttcg ctgaataatc aaatgtaaat aggatggatg gtgttgccgc gcatacatca
     2161 ctagactttg aaattctgta aaatcttggt tctcaataat atcaataatc ttattaaata
     2221 tttcggactg accttgatct aataaaaatt gatttaagtc aaaaccacaa ccactttcaa
     2281 tatcgttgat gtcataaggg gttttatctg tattagacgc atgaataaaa taatcaaaca
     2341 tgcccttagg ggacataatt atttcaatat gactaggtgt atttaagtgt tgttgaagta
     2401 attcagagac ttgggaataa ctttttaaag aatcaaaaaa caaagctcca tgtttatgtg
     2461 acttcttaat ttctcctgtc gagtgatcaa tatcttgatt atgccacgga cttaaaatat
     2521 aggggatatg catttgttcc aaaatatctc ggtagttaga tggcgagctc tcttcatata
     2581 ttaagaaagc ccacttattt gaacgtttat cttttgacat catcaacatc ctttctgtga
     2641 ttattgatta atgatgccat gggggtcgta gtaaccccat ggcactgtta agatacacat
     2701 gcgcttgtgt ttatcacttc gtgtaccaca acgcatgtgt atcttaacgt ttgtggcctg
     2761 caaaccatag ataacgatga tgacgttgag gttttgaaaa gtaataattc gggtgcatat
     2821 gtgtaatttc ttcatgaatt tgaggttcaa tcttttttaa tatatcgtga gcttgctgtt
     2881 tccggggaat tttaattgcc acacggactt cattttgacg aacatcaacg agcgattttc
     2941 caaccatttt attaaagtat tgctggacag aatttgtttt acttttgccg ttattttgcc
     3001 aatcctgagt cgtgtctgtg tcaacatctt gtttaagata atgtcgtaaa accattgtgt
     3061 gataaacaga tttgatatga ttcgtgagtt gatctttcaa taaacgaatc attaaatcga
     3121 taactattaa catcaatgct aagactaata agtaaaatgt aagttgatat acaccatttg
     3181 aaatgattgt gatatagtgt gtgacgtttc gcgtatcgat aatatcaatt tgagacacaa
     3241 taaagtttaa taggacaaag agtttactaa ccataactgt caaaatagcg aacaggaaca
     3301 agtaaatgat aatatcatac acacgcatga aataggtttt cctcatcaca atacacctgc
     3361 tttcgtatag taagtcggac ataacaaggg taagacttga tagggagatt cactatcaat
     3421 cacttggatt agacctgtcc ctttaccaat gggtatcaca ataccttctg gatctaaatc
     3481 ggggaataaa aattgtgtgg tttttttatt aatattaccg atttgaatca gcacattgag
     3541 ttgttctcta acggaaaccg ggatggtttg atgatcaaat cgttgagaca ccagtaataa
     3601 atgaactttg gtggcacgac ctaataaagc aatttgagat agtaatgaaa agaacgcgtc
     3661 tttaatggtc ttattcacac cttcagctaa agcgagcact tcatcaatca caatggttag
     3721 gtgatcaaat tgatagtctg gatcgtcata aagaatggtt tgtcgttgtt gaataacttg
     3781 aaggcaatga cttaagtttt cattaatttc agataaaaaa tcagacttag atcgattttg
     3841 atgagggtga atcacagtaa tatcatgaat acgtgcccaa cggctcggtg tatcaaactt
     3901 agggtcaaca ataatgagtt ctgatatcgg ttttaataca cttagtaagt acgtcagcat
     3961 ataagattta ccactgcctg aattacctgc gatcgctata gatgtaatgt tttgatagtt
     4021 taaagttaat tgtttcatga tcggaatttg ttgattcgtt agagacgacg taaaacgatc
     4081 taaatcagaa atcactaagc gttctgatat cccttgttgc catgggaaaa acaaagcgcg
     4141 ttgcgtatga atatcgtcgg tatccatagg tacgaaatac gcagaattct gttttaacaa
     4201 tgtgaatttg ggatataaag ctgcactcgc aatgagaaat attttttgat ataagtcatc
     4261 atccacaata tagcctgcag gcaggcgagg aagaaagtaa aaaccttctt ccgtgacctt
     4321 gcaggtgaaa ctattggtat aactggtttc gccttgcatc atggatccta gtgccatatt
     4381 taagctttgt aggagatatt gttcgagctc tttggctgtc attatttaac ctccttcaga
     4441 tctgaagctt tgaagtaaac atcataacgg acttcacaag cttctaaatg atcaaaagta
     4501 atgacgctca tataattagg taatgtcact tcattttcga atttaactgt gaagggcggt
     4561 aagccttctt gaacaaacca ggctttatac gcaataattt ctccggtagg ctgattattc
     4621 tcaaaacgct gttgcggata aagttctgta cttaagctat aaatgggttt tttattatca
     4681 atataattgg aagctatttc agttgaatag ccaccttttt tgaaattaga ttgaattttc
     4741 atgtgaaaca tcctttctat cctattgatg cgcatcgttt aggaaatata aatagaatta
     4801 atcaaagata tctgtgattg attaaatttt cgcaaatgaa gtgataaaat aataggtgaa
     4861 aaaatttatt cggtttttgg aggtaatagc gtgattatca ttaataacaa aggaatcaat
     4921 gacttagatt ttaattattg gatgaataat caattaactg atgacaatat cgaagaaatt
     4981 ttagaggggt ctgatttaag tatggaacaa gaaattttta aaagtaatta taaaaaattc
     5041 ttggagatag atggcaaaaa ggaaagatgg tattctctgg aagaagctgc gtatattatt
     5101 aatgggaatt atttttcaat ttatgaggaa gatagcaaaa agcgaagtgt cacaacagac
     5161 tatgtaaaaa ataaaagtaa tgatatctta aataatatag aaaatggaac aaaccaaaat
     5221 tggaataaat atcattaccc acaaaaaagg aagtttgcat tcaaaaaagt aaagtatgtt
     5281 aatgaagata tgatcgatga aatattaaga gatgatgtaa caaaacctga aaaaataaaa
     5341 cgaggtaata tatcaatcga agagttgcta cctaatcaaa atagaatagc aaaatatatt
     5401 agacagaatg agaatataca taataaaagt ataatgatag attacctaaa tcaattaagt
     5461 gatacactgg caaaatcatt agacgacgta cgttattttt caaataaact atcattattt
     5521 aaatctgtta ttaaagattc tagagaaata gcacaaaata tacataggga tcacgatata
     5581 gataataaag aaaaatatga acttctgaaa aaagaatata gtaatttttt agaaaactgt
     5641 atacgttttt ctaatgaata tttagatata ctagatatca aaaatatttt taatattttt
     5701 gatactaaga aaattgtttt aaatctgtct tattatacga aaatgtggga ggttcctgat
     5761 attaataatg aacaaccgat aaataataat ttacaaaagt ttgttgattt gaaaaagaag
     5821 aagtatttaa ataatgtaca ttggagtaaa aataagatac ttaaacaatt aaatgaaatt
     5881 gaagttaaac ccgttacttt aaaagatggt actagtgaaa cagaacgcgt ggcagagtgg
     5941 atgtatagaa ataaaacaaa agttgtttat gaaattataa ataaagaatt tgatgatgtt
     6001 tatgatttac ttaacggtat gttgaagtct gaatacacag aacttatggg ctatatgaga
     6061 atatggcata acttaagcaa aaatttataa gtcttagtaa cctgttatac actttaattg
     6121 gaggagttaa cgtgtatttc aaaaatatgg atttcttgat tgacctatac aagaatttta
     6181 acgaagtagg gatttttgca gtaatatata ttatatatgc gcttattcaa attctaagtc
     6241 aaaatatttt atataaaaga caaaagatgg aaagagtaaa aacactgata atcaatataa
     6301 ttttatacat atttataaca ctagtagcat taatgtactt gttagcaatg attttttatt
     6361 cactcagtgc atatcctaaa gaagaagtga ttaaatatat aacagattgg gataaaatta
     6421 gtttgccagc tatattactt gttctttatt cgttattatt ccctattttt atatttccat
     6481 ttgtaggaaa acgacgtaga aaaaactatt ttgcagaaaa tgtaaataat tgtattattg
     6541 aaagagaaat tatagataga gtgagtatta atggtagaga taaattaatt ctaaaagatg
     6601 ccttaggata tcagacagaa aaagatataa caggaataaa ggatttaaaa attagtacat
     6661 ctcaaaaaaa atcttggtta acgttagaag acattaaaat agctacgatg agtctaagag
     6721 ataaacaatt actgttaaaa atgattatag gtttaataat atttggggtc cctacagggt
     6781 attttgtgtg gaacttcatc agtgtcgttg atgattggga tagaataatg cacgcaaatg
     6841 atatatttat gtatatgggt cttttcacgt taccattaat ggtaacagtt gagttatatg
     6901 tagttgcatt tattattacc aaaaatttat ttaaaaagaa aaaatgataa caaatttaga
     6961 ttaagagaaa ataacttatc aaaggtcgta tattagaaca tgatatatat agttcgccta
     7021 tctatcaaga atcaatctag tcgcagagag ggatcattac tttgctaatc attttcgtta
     7081 attggactat aacattggtt ggtggagaaa tgtaaaagac tattattatt gattttgtag
     7141 gatttttttg gttaataagt cttttcttat actatcaaca atacggtaat tagcttgtca
     7201 aaggatttta ctctttccaa tcaattgtgg atttgtatcg gtgtagaaag tattttgtac
     7261 caagcgtcta cctgctttat ttctaatgaa aaatcagtta gtaaatcttt aatcattttt
     7321 ctcttagaaa accaatttga acggttctga gaaatataat ataaagataa aaaattgaca
     7381 tatgatttat acagtgctaa aatttaaaat gtatatagga gaggtcttgc cacaagtaga
     7441 cattgaaaaa atagagagtc catgctaaaa gttggaattg aaaaaatgga gaggtcttgc
     7501 cacaagtaga cattgaaaag cgaccaaata tttggtcgct ttatttttat actgtaggag
     7561 aaattatgaa attatactat gttgatgaag attatattaa tgaattaaga aatgtagatg
     7621 agagagtatt attaaataaa tccactcgtc cttatttagg agttgtatta tctattaatg
     7681 atcttaatta ttttgtcccc ttaagttccc ctaaagaaaa taaaaaacta aataatcaac
     7741 tatcaataaa attgtttgag gttaataata ttcaaaatag attaggatat ctattatttt
     7801 taaatatgat acctgttcct gataaatatc tttctaaaat agatatgcaa tacataaagg
     7861 agcaagattt agaatattat aacttattaa ctaaccaatt aatttttatt aggcaagaaa
     7921 atcaaagaat cgtaaataaa gcccaaaaag tatataaaaa tgctgtgata aaaaaagttt
     7981 cattttttga atcaatgtgt gtagattatt tagcattgga aagatatgtg aaagatttaa
     8041 aacagtaaaa aagataattc tgtcaataat tcccctcaac atactcagaa gaattttagt
     8101 gtaaagtctt tgtaattgtc tatcttagtt aattagatgt ttactattat ttctatatta
     8161 atatatagct aaaattaata aaatagaagt cattagctga attacttatg aatcaaaata
     8221 aattttatat acaaaatgtc atttttgagt acgctctaaa taaacaaaaa tagtcctctt
     8281 attaaaataa gaggactatt tttgtttaaa attattcaag accattcgct ttctaacata
     8341 ctcatttgcc ataaattata atattctcca tttaattttc taaagtctct tttttctcct
     8401 tcttttataa atccaatctt tttgtaactt ttaatagctg atttattaaa ggcaaaaaca
     8461 cctaattcaa ttctgtgtag tcccaaatct tcaaaagcct ttttcaataa tttctttatt
     8521 attttagggc ctaatccttg gccacgcatt tgcggatcac ctactaaaac tttacttaac
     8581 gtggcggaac aatttttaaa atctatatta tttaaagcaa tatgacctat aatttttttt
     8641 gaattatttt cttcaatgat aactttataa attattttac tagaattttc tttatttgtg
     8701 tctttaatat attcctttaa ttgttcttca tctaggggat aattaaaatc tgtacctgcc
     8761 catttgacta aaagttcagg agagtttatc cagtttatta ataaatcaaa atctttctcc
     8821 tcaaaatatt caaacttaat caataaatta ctccttaaat aataggttat taactataaa
     8881 aattcagtga atgttgcaat ataaacaacc actacaattt tttgatactt tcttcatcaa
     8941 ctttctatct taaattttcg attttttata aagcgttttg tattatctaa ataactcttt
     9001 acaatttact gatttttaag cttttgctaa tagatttatg caactttaat attataagta
     9061 aatctatgca cttcatcatt aaatttaaat tctgcccaaa ttttatacat ccctttttta
     9121 ggaaaatgag cataaaaggt tgtagaatca ggtgattctg ggtgaacatg aatataatca
     9181 gttaattgct catcaaatat aatcacatgt cctaaagctc ctaaataagg ttggggagtt
     9241 aattctgtat tgaaagttaa agggacatgt tcatcttctt tagcacttat agaatttaaa
     9301 gttacatgaa ctcctttgtt aacttttacc caatttttat cagaatttaa agatgttgta
     9361 gaggttattt tatctccaat ttgcagttca ataggatgaa cggaatacac atggtttttt
     9421 ggtgtaacat caacaaaagc ctggtaagtt cctggctcta attgttggtt aattataaat
     9481 aaaccttcat gctttttttg agggtgtagg tggtaatatt tctccatgtc attagatact
     9541 aaaacgaaat gcatttcttt ttcatgcata gtatctaata atggggcatt attaaattca
     9601 tcttctaacg taatttctat attaccatct ctatatacaa catttgcttt aatttcgggt
     9661 ttgtttgaat gatattcatg attatgattc atatttttat cctccttaat ttttaataag
     9721 ggcatatcat taaacgatat gcccaactat ttaaattatt taattacatc gtaaccttga
     9781 tcttcaatag cttctttaaa gtcgttgaaa gctacttgat tttcatcaaa ttcaacttcc
     9841 acattcccat tcgccaagct tacttctgaa gatgttacac catctaatcc atttaatgct
     9901 ttttcaattg aatgcttgca atggtcacag ctcatacctt ctacattaat aacttcgtta
     9961 gtcaatgttg tcacctcctt tcaagaaata taagattctt ataatttcat acgttttaga
    10021 cgtaaagcgt ttgtgacaac acttacagaa cttaaagcca ttgctgctcc cgcaacccaa
    10081 ggtgctagca gaccaattgc tgctataggg atacctgcaa cattgtaacc aaacgcccaa
    10141 aatagatttt ggcgaatatt acgaattgta gatttacttg cttttattgc ttttggaatt
    10201 aataaaaggt ctcctcctaa aatagttata tcagcagctt cgattgcaac ttctgtacct
    10261 gtaccaatgg caataccaat atctgcttta actagtgctg gagcatcatt gacaccatct
    10321 ccaaccatag ctactttttt accttcagat tgaatttctg ctactttaga agctttttct
    10381 tctggtaaaa cctctgcaat aatcgtgtct ataccaactt gttttgctat tgcttgtgcg
    10441 gtacgtttgt tatcaccagt taacatagca acttcaatac ctaattcatg aagtttttga
    10501 atagcttgtt gggcagtatc tttaactgta tcagctacag cgacaacccc tctcaattcg
    10561 ttatctacgc ttataagcat tgcagttttt ccttcttttt caaattgagc gagatttgtt
    10621 tcagcttcat tagtttggat tcctttttca ctcattagtt ttcgatttcc gacaaaaagt
    10681 tctttaccat caattgttgc atttataccg cgccctggta tagcttcaaa atggtctact
    10741 tctaaaaatt ctaatgattt ttctttagca taacttacga tagcttcagc tagtgggtgt
    10801 tcagaacctt tttctgcact agctaacaat tgtaatgttt gatcatctcc actaaaatca
    10861 gtgacttcag gtgtgccatt tgttatagtg ccagttttat ctaaaacaac tgtattaata
    10921 gcgtgtgtac cttcaatgtg ttctccacct ttaaatagaa tgccattttc agcagctttt
    10981 ccggtaccca ccattataga agtaggcgta gctaagccta acgcacaagg acaagcgata
    11041 actaatactg ctattgcagc aactaaggct ggttcaaatt gtcccggctg aactaatgaa
    11101 atccatataa taaatgtgaa aatcgcgata cctacaacga taggtacaaa atatccagaa
    11161 ataatatctg ctagtctttg tattggcgct ttagaacctt gcgcttcttc gacaacttta
    11221 acaatggagg caagagctgt atctttacca acttttgttg cttcaacagt aattgctcca
    11281 tttttattca ttgttgatcc tataacatta tcattttgca ttttttcaac aggaatagat
    11341 tcacctgtca acattgactc gtcaattgaa gtcatacctt taattatttt gccatctact
    11401 ggtatttttt ctcctggttt gataactaaa tagtctcctt cttttacctc acttaaagga
    11461 accatagtct cttcaccgtt gcgtaatata cgtgcttctt tagcttgtaa attcaacaat
    11521 ttacttaacg catttgttgt ttgtgtttta gcacgtgctt ctaaatactt tccgaaaaga
    11581 attaaagtaa ttaatacagc acttgtttca aaatataggt gtggctcata atttgtatta
    11641 attaaccact taatcgattc ataaatacta taaaagaagg ctgcgcttgt acctaaagcg
    11701 acaagaacat ccatatttgc tgacccatta cgaaggtttt tataagcgcc tacataaaat
    11761 tgccaaccaa taacaaattg aacaggcgtt gctaatacaa attggaacca cgggttcata
    11821 aatatatgtg gtatttgaat accaaataaa tgaacgaaca ttgtcattaa caatggagct
    11881 gctaaaacag ctgaaacaac taatttaatt aactgtcgtt ttaattgttt ttctttttgg
    11941 gaactttttt ctgatgcttc ttttttaggt tgtgcctcat accctaggtt tttaatacgt
    12001 tgttgaaatt catctacaga cgtcatatca gggttgtatt ctacagtagc actttctgtg
    12061 gttaaattaa ctgtagcctt atttacacct gagattcgat ttaaaacttt ttcgatttta
    12121 ttcgaacaag ctgcacacgt cattcccatt acatcgagat ccactttttc ggttaaaact
    12181 ccataacctg ttttttgaat tgtatttgca atatcttcta atgatgtaac attggggtta
    12241 tattcaattg tagctttctc tgtagaagga tttacattag cgttaacttc atctaattta
    12301 tttagatttt tttctacttt attcgagcaa gctgcacatg tcatgcctgt gatacctaat
    12361 gaggtttttt taatattttc actcaattat ttctttcctc ctattttgaa aattgtttta
    12421 atacaaccat caattctttg atactttctt ctccgttgcc atttttaata ccttcactta
    12481 cacaattaga tatatggtct tcagttacta taaaacccac ttgttttagg gctgattgta
    12541 ttgctgttat ttgtactagt acatctatac aatatctatc ttctgctatc attgattgta
    12601 aaccgcgcat ttgtccttct aatcttttga gtctattgag caatgcgtca ttgtttttaa
    12661 cagtagtagt gttcaatttc acccctcctc atatacccta acggggtatc tcttgttgga
    12721 atctatatta tacccctagt aggtataagt caatacaaaa gtttcatata aaaaattaat
    12781 atttatagtt tgttttaaga ggtacacttg tataaaatgt atgctaaaac ttatattagg
    12841 agagatatat ttggataaaa atatacaact tgagctttac acaagaccta catgctctga
    12901 ttgccaagaa tcaaaaaggt atttaaactc tcaagagatt agttatagtc ataaagatgt
    12961 aagtcaaaat ttggacttag aagaagaaat gaaaaaaata tcaggcaacc gaattgttcc
    13021 cttatttgtt ttttataaaa aaattttttg gggtaaaaaa aagttgttta aatattacgt
    13081 gggatttgaa aataacaaaa aagatatatt aaatatattg gaataattaa ataaacagcc
    13141 attattaaaa aataatggct gtttatttaa tgatgatgtt gactgtcttc ttctttcacg
    13201 atacaaaaca atttttcact atgattattg ttagaagttt cagtctgtat tgtgacatgt
    13261 tgaatatttt gatgattgag ttcatgttct atacgtttaa gtaaaaactc attttcagta
    13321 atggtcattg tatcttctac aacaatatga caagataacg cgtttaatcc gctagttact
    13381 gaccaaacat gaaagtcatg aatattttta acttctttga attttttaat agttttaata
    13441 atgtcttttg tatttatatt gcttggtgct ccctccatta atacatgaag acttgatttt
    13501 gttacataaa agccgctacg tagtactaaa attgctacaa tcacacttgc taaaggatcc
    13561 gcccaccccc atctaaaaaa tataatgaga agggctgcta taactgcacc tatagatcca
    13621 agcatgtcgc ttattacatg caaatatgct ccacgcatat ttaagttttc ttctacatcg
    13681 ctcccgcgca gcattatcca agccacaata atattaataa acaagcctac caaggcgata
    13741 attaacatgc ctgtagaagc tacctcaggg gggtttttaa atctctcaat agcttcataa
    13801 aaaatataga tagctattaa catcaaagta ataccattaa gtacagctgc tagtatttca
    13861 aaccttttgt agccaaaagt tttatttgta ttagcttgct tcgctcctaa agtaaatgca
    13921 attaaagcaa tacctaaaga aatagaatca cttaacatat gaccagcatc tgaaattaac
    13981 gcaagactgt tagtaaagaa accacctaac ccttctacaa tcatgtaact tgtaataata
    14041 ataaaactaa ttaataaagt ctttttgttc gcgccatgtg tatgattatg attgtgatcg
    14101 ttttccattt aatccctcct ctttttaatg atgaaaaata ttttctataa tttgaatttt
    14161 tgtttttata actatagagt taaaaaatat aaaatttcaa ttaatgtttt gttactcgaa
    14221 gaaaatcata ctaacttatg aatatatgct catatattca taagttagta tgatttttat
    14281 cctttgtcaa tatagaaatg ctttgtattt tgtatattaa ataaaaaccc tactttgctt
    14341 tggacagtag tgggattttt gcatatgata aaccacactt cacttgctaa atattaacta
    14401 tattataatt aacaagtgat aatttctttt tagagaaaat aatgtattca cgcctttagg
    14461 cgtgaataca ttattttttt ttgaatagtt tagaaaagat agattgtttt tgttcatttt
    14521 tttttgatgc ttttggagta atgatatctt cttttgaatc tatattatca gtttctattt
    14581 ttttggtatt acttaatata ttttggctat ttaaattcaa agattgttct tgttttaatg
    14641 caattgttaa atcgtcaatt tgtcgattct tttgtcgaat ttctgattct aaatgctcta
    14701 tgtatttatc gatataactg ctatattggt tatttaatga ttctgttttg tttgtcgatt
    14761 tttcatcaaa ttttgtcgat tcttttgtcg tttttttatt taaaattgtt tttagataat
    14821 ctattgtatt atcatctatt aatgatttgt tacctacttt gtttaccttc aaatttgaag
    14881 gtaaactttt taaatgataa tgaattgttt gtttagagac atctaaaagg gttctgttgc
    14941 aaagtaaaaa atatagctaa tcactaatat atcatgtcag tgttcgttta acttgctagc
    15001 atgatgctaa tttcgtggca tggggaaaat ccgtagatct gaagagacct acggttcttt
    15061 ttatatagag cgtaaataca tttaatacct tttaaagtat tctttgccgt attgatactt
    15121 tgatatcttg tctttcttac tttaatatga cggtgatctt gctcaatgag gttattcaga
    15181 tatttcgatg tacaatgaca gtcaggttta agtttaaaag ctttaattat tttagccatt
    15241 gctgccttcg ttgaaggtgc ctgatctgta actacctttt gaggcttacc aaattgttta
    15301 atgagacgtt tgataaacgc atatgctgaa tgattatctc gttgcttacg caaccaaata
    15361 tctaatgtat gtccctctgt atcaatggca cgatataaat agctccattt tccttttatt
    15421 ttgatatacg tctcatcaat acgccatttg taataagctt ttttatgctt tttcttccaa
    15481 atttgatata aaattggggc atattcttga acccaacggt agatcgttga atgatgaacg
    15541 tttacaccac gttctcttaa tatttcagat atatcacgat agctcaatgc atatcttaga
    15601 tagtagccaa cggctacagt gataacatcc ttgttaaatt gtttatatct gaaatagttc
    15661 atacagaaga ctcctttttg ttaaaattat attataaatt caactttgca acagaaccat
    15721 ttagaatatt aaaattcctt cattacactc ttggcggttt cacttatcaa cttatcattt
    15781 ggcttatcac ttttattgtc tttattcgta aaaatgacta aaacaatagg ttcagattgg
    15841 cccttaggat aaacaaaagc aacatcattt ctagaagcat atgttattgc ttgaccactt
    15901 ttatcagcaa ccttacagtc ttttgaaaca ccgtctttaa ttaaagtatc tccgctttta
    15961 ttatttaaca ttaaatcaag taagaatttt ttgttttctt tgcttaattt tccatttgcg
    16021 ataagtttat ttaaagtctt accgaaagca gcaggtgttg aagtatcttt tttgctcttt
    16081 ggtgaatagt aatttaattc tatctcatat ctaactggat ttgttacttt atctcctagt
    16141 tcttttagac gttgtttaac ttttttgatt ccaccaattt cttttataat tttattgttt
    16201 gctgtattat cactatatgc cattgaagcc tcaataagtt cttttaaagt gatatctttt
    16261 cctacatatt tttctaaaat aggagaataa gcaactatat catctttgtt aatatgtatt
    16321 tttttattta acttattata aggtacttgt tctaacaaaa tagcactatt tatcgctttt
    16381 gaagtcgaag cataggcaaa tctcttatct gaattaaatt ttacttcctt accactttta
    16441 gtatctaaag cataaacacc aatatgagca ttatattttt tttctaaatc atttaactct
    16501 ttggcatgtg aactgtttga attacatgca cttaaaacta aagcaattgc aattaaaaat
    16561 attaactttt tcaaaataaa ccctccaata ttacagttgt aatttttaca aattaataat
    16621 attacaattg taatattggt gtcaattgtt tattataaat aattgaaaga aggtgtcaaa
    16681 atggctaaat tactaataat gagcgtagta agcttttgtt ttatatttct attgttagta
    16741 ttttttaggt atatattaaa acgctatttt aattatagtt taaattataa agtttggtat
    16801 ctaactgtgc ttgctggatt aattcctttt atcccaatta aattctcttt tataaaattt
    16861 aataatgtga ataatcaatc gcccacagtt gaaagtaggt cacacgactt gaaccataac
    16921 ataaatacca ccaaacctgt tcaagagttc acaacagata tccataagtt taattgggat
    16981 tcaattgata atatctgcac agttatttgg atagttttgg ttattatttt aagttttaaa
    17041 tttttgaaat ccttattata tcttaaatat ttaaagagac agtcacttta tctaaacgaa
    17101 aatgaaaaaa ataaaataga tacgatactt ttcaaccatc aatataaaaa aaatattgtg
    17161 attcgaaaag cagagactat tcaatctcca ataacttttt ggtatgggaa atatattatt
    17221 ttgattccta gttcatattt taaaagtgta attgacaaaa gactaaaata tataatattg
    17281 catgaatatg ctcatgctaa aaatagagat actttacatt taattatctt taatatcttc
    17341 tctattgtta tgagttacaa tccattaata catattgtaa aaagaaagat aattcatgac
    17401 aatgaagtag aagccgatag atttgttctt aataatatta acaaaaatga atttaaaact
    17461 tatgcggaat ctattatgga ctccgtatta aatattccat tttttaataa aaatatatta
    17521 agccattcat ttaatggtaa aaagtcatta ctcaaaagaa gattaattaa tataaaagaa
    17581 gccaatttga aaaaacagtc caaattaatt ccaattttta tttgtatttt tacttttttg
    17641 ctcatggtaa ttcaaagcca gtttttgatg gggcaatcca taactgatta taattataaa
    17701 aagcccttac agaacgatca ccaaatttta gatgaaagta aaaattttgg ttcaaatagt
    17761 ggatctttcg tcatgtacag catgaagaaa gacaaatact atatttataa tgaaaaagaa
    17821 agtagaaaga gatattctcc tgattcaact tataaaattt atttagcgat gtttggactt
    17881 gaccatcata tcataagtga taaaaattca cgtatgtcat ggaatcataa acattatcct
    17941 ttcgagtctt ggaataagga acaagattta aatacagcaa tgcaaaattc agttaattgg
    18001 tacttcgaac gtattagtaa tcaaatacca aagaactata ctgcggctca actcaagcaa
    18061 ttaaattatg gtaatgaaaa cttgggaagt tataaaagct attggatgga agatagtttg
    18121 aaaatatcta atcttgaaca agtaatagtt tttaaaaata tgatggaaca aaataaccat
    18181 tttagtaaaa aagcaaagaa tcaattatct tcttcattat tgattaagaa aaatgaaaag
    18241 tatgaactgt atgggaaaac aggtacaggt atagtaaacg ggaagtataa taatgggtgg
    18301 tttgtaggtt acgtaattac aaatcatgat aagtattatt ttgctacaca tttatcagat
    18361 ggaaagccgt ctgggaaaaa tgctgaatta atcagtgaaa aaatattaaa agaaatgggt
    18421 gttttaaatg gccaataagc aagttgaaat atctatggct gaatgggatg ttatgaatat
    18481 aatatgggat aaaaaatcag tatcagctaa tgaaattgta gttgaaattc aaaaatataa
    18541 agaagttagc gataaaacga ttagaacatt aatcacaaga ctatataaaa aagagattat
    18601 aaaacgatac aaatcagaga atatttattt ttactcatca aatattaaag aagacgatat
    18661 taaaatgaaa actgctaaaa cctttcttaa taaactgtat ggaggggaca tgaaaagttt
    18721 agtgctgaat tttgcgaaaa atgaagaatt aaataacaaa gaaattgaag aattgcgaga
    18781 cattttaaat gatattagta aaaagtaatt agagatatgt ttcaaacata atacatatgt
    18841 aaactatgct tgactcttat taaattagtt ttgttaataa catttaaaat attttattaa
    18901 atatgagagt gtccagaaaa taaccatttt ctgtacactc tctttttata tctagatata
    18961 tagctagtat acatatttta gtgttcaata acccaacaga aaatctatgt tcataaatat
    19021 ggttagaatt aagttatggt acaatgaaaa tctacatagg aggtttgtat tttgaaaata
    19081 ggttatgcaa gagtctcaac tggtttgcaa aatttgaatt tgcaggaaga tcgattaaat
    19141 caatatggtt gtgaaaagat atttagcgat catataagtg gatcaagaag taaacgtcct
    19201 ggtttagata aagctattga atttgcgagg tcaggagata cgattgttgt ttggagacta
    19261 gatagattag gacgtaacat ggaagattta atcacattag ttaatgaact taataatcga
    19321 ggcgtgagtt ttcatagttt agaagaaaat ataacaatgg ataaatcaag ttctacagga
    19381 caattgttat ttcatttatt cgcagcattt gcagagtttg aacgtaattt aattttagaa
    19441 cgttcttcag cggggcgaat ggcagctcgt gctagaggac gctatggagg tcgacccgaa
    19501 aaattaaata aacaagattt gactttactc aaaacacttt atgataatgg aaccccgatt
    19561 aaaactattg cagagcaatg gaaagtttca cgtacaacaa tctatcgtta tctcaataag
    19621 ttaaataacc aagaaaataa agataaataa aaaatattac tgagttttaa gaaagataaa
    19681 agttagacag gatacaccct aatcatacag atacagttgt tgaatttata gcaattaaaa
    19741 cgtatgatta gggtgtatat taattatgag gtgaaatcaa tgattgttgg ctatgcgaga
    19801 gtatcatcga acgatcaaaa tttagaaagg caacttgaaa atttaaagac gtttggtgct
    19861 gaaaaaatat ttacagaaaa acaatctggg aagtctattg aaaatagacc ggtatttcaa
    19921 gaagcactta attttgtgag aatgggcgat agatttgtag tagaatcgat tgatcgctta
    19981 ggtcgcaatt atgatgaggt gattaacaca gttaattatt taaaagacaa agaagttcaa
    20041 ttgatgatta ctagcttacc tatgatgaat gaagtcattg gtaatccttt attagataag
    20101 tttatgaaag atttaatcat tcaaatatta gcaatggttt cagaacaaga acgaaatgaa
    20161 agtaaacgta gacaagctca aggtattcaa gttgcgaaag aaaaaggtgt atataaaggg
    20221 cgtccgttac tttattcagc gaatgctaaa gatcctcaaa agcgtattat ttatcataga
    20281 gttgtaaaaa tgttagaaga aggccaagca attagtaaaa ttgcgaaaga agttaatata
    20341 acaaggcaga ctatttatag aatcaaacac gataataatt tggattaaca aatgggttat
    20401 tcagcattat catgtgtatg aactttataa ttactttctt atcttcaatt acgaacaaca
    20461 tgccaactgt tttaatagat gcaatattga ttgatcaatc taatgctaca ggtatattaa
    20521 aagaaggtat actttaaggc ttaaaattac gtcaattagt tctttagcaa cattattgtg
    20581 gctatacgtc ttaacacaaa aaggtatgaa aatttcgcgg ggaacatact ttaaaactgg
    20641 aattatcatt actattccag tcctatttgt aactctctta ggtttatatc ttacactata
    20701 ttttaagaaa agaggtttta attatggata agaaaacaat ttattttata tgtactggca
    20761 attcttgtcg tagccaaatg gctgaaggct ggggaaagca aatattaggc gaagactggc
    20821 atgtatattc tgcagggatt gaaacacacg gcgttaatcc taaagcaatt gaagctatga
    20881 aagaagtaga cattgatata tcaaaccata catcagactt gattaatagt gatattttaa
    20941 aggaatcaga tttggtcgta acgttatgta gtgatgcaga caataattgt cctattttac
    21001 caccaaacgt taaaaaagag cattggggtt tcgatgatcc agcaggtaaa gaatggtcag
    21061 aatttcaacg tgttagaaat gaaataggta atacaattaa agattttagt aaaaacatca
    21121 agtagatact tgatattttt tactactaat tcactgattg caaacttaat aaattaattg
    21181 aaaagaatat ttgtacatat taaaatcgaa ttacgatatc gtaattcgat tttaataagg
    21241 agatatattt tgaaaagtaa aatacaccga aaattatttt taggatttgt ctatatccat
    21301 atattacatc atgcaagcga agataaaata tatggggctt ggatgattaa agaattatac
    21361 gaacatggtt atcatatgag tcctggtact ctttatccaa tactccatac actagaaaac
    21421 gataatcttt taaaaagcgc aacaaaaact gtaaatggaa aaaatagaaa gtactattca
    21481 ataactccaa aaggcgaaaa atttttaaaa gaatctagag aaaaattaaa agagttaacc
    21541 aacgaaatat aaggagacct ttatgtataa atatataaat atttttttgt tgcattaaaa
    21601 cttggtttat tatcattcgg tggacctact gctcatttag gctattttta tgatgagtat
    21661 gtaaaaaaaa gaaaatggct tgatgaaaaa gagtactctg atttggtagc actatgccag
    21721 tttttacctg gtcctgcaag tagccaagta ggtattggta taggaactat aagaggtggc
    21781 atcggaggag gcattatctc atttatcgga tttacgctcc catctgtaat tatactaatg
    21841 attttttcag cgctatttac aaacagtgat gtaagtttcg ataaagtccg tataattgtg
    21901 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
    21961 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
    22021 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
    22081 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
    22141 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
    22201 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
    22261 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
    22321 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
    22381 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
    22441 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
    22501 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
    22561 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
    22621 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
    22681 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
    22741 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
    22801 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
    22861 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
    22921 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
    22981 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
    23041 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
    23101 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
    23161 aaaaacattg tatagcattt tacacaggag tctggacttg actcacttcc tttattattt
    23221 ttcatttttt taaactattt aatactaatg tcttttataa tagcttttca tatattatat
    23281 aatcaatctt tataagtcct tttataaatt tcttttctac cattttcgat aaattcctgt
    23341 ttaatatttt taattccata aacaatagtt tcaataggat aatattcttc aactatatct
    23401 tgatattctt ttgctttctc aatatctata tttccataca ttcttaatat atcttctcca
    23461 aaatttgttc ctatttcttc ttcactatct tcaagtaagt atataaaatc acaatattca
    23521 tctataattc cagaatctcc aaaatcaatt attccagtta atctattatt gccatctaac
    23581 aatagatgat tacaactaaa atcattatgg cataaacact ttttaccctc aaaaactgtt
    23641 gttgcattta gtctttccat aaaactttct atataatctt tttctatatc agttaaatca
    23701 ttataaatag tttcacgcaa caatatatac tcttctaata cattttgttt attatcaata
    23761 gtacattcac taatatctgt ataatctaaa ccgtgcattt gtcttaaaaa actggcaata
    23821 tctcgtttta acaaattttg ttcttcttct gacatagtag aataaatttc tggtgttaaa
    23881 aaagttcctt taatttcttt ataacctagt atagataatt catcactaat atacgaatat
    23941 tcaatattag gaatttttac attagtttct aaatttgtat ttaaaaaatt atatattgct
    24001 ttttcttttg cataaccttt tttcttatta gtactaaatt ttgttttaaa aatgtattca
    24061 ttattaacta aatatgccac actatcataa ccactaccga ttatttcaat actatctact
    24121 ttgaaattat caaagtaatg ctcaattaaa tatttcattg ccttaacatt tgtggcatta
    24181 tcatcatatc tatattccat taaataacaa tcttcttttt tgccctcgtg taattcatgt
    24241 tctggcaaat cttcaataat tctaaaacca gatttttggt atgcccttat tgctcttgga
    24301 ttatttttat gagggtctaa aataactgca ttagcatttc tttctttttt caaaaattca
    24361 aaaatcaatt taatatatct tgtaccaatt cctttactcc aataatttgg ctctcctata
    24421 aattgatcca taccatagac tatctcatca gtttttggat aatgataatc agtatataac
    24481 tcatcataca ttttatatat ttgtccatat ccaataggaa cattgttata ttcaataatt
    24541 actctaaaaa cttcatcttc ccaaggctct gtataatgtt tttttaatga ttctaatgta
    24601 tattttttat ctctaccacc ataaaattct aatactcttt catcagttaa ccattttaac
    24661 atcaaaggaa aatcatcatc tattaaagtt cttatacata tttcattttc aactatattc
    24721 atttatttat cacctttttc ataatcatat acatatacta tttcatcttt ataatcattt
    24781 ttaccaccta atttttcata tacatggcaa gctctaggat tacctttatc agttattaaa
    24841 aacatttcag aacaaccaat ctctttagaa tattccttaa taaaagataa taattttgaa
    24901 ccataacctt tgtcttgata gttaggtaac attcctattg agtgtaaata aaacattgtt
    24961 tttccatcag gtcttaaaag tgtatagcaa tatgcaaatc ctataatttt attattttct
    25021 ttagctataa acccaaatga actggtatca ttaagaaatc cttttaaatt atcaatatca
    25081 aaaaccatat tatcatcaat taaaacttct tccataaact cagtcaagtc cagactcctg
    25141 tgtaaaatgc tatacaatgt ttttaccatt tctacttatc aaaattgatg tattttcttg
    25201 aagaataaat ccattcatca tgtaggtcca taagaacggc tccaattaag cgattggctg
    25261 atgtttgatt ggggaagatg cgaataatct tttctcttct gcgtacttct tgattcagtc
    25321 gttcaattag attggtactc tttagtcgat tgtgggaatt tccttgtacg gtatattgaa
    25381 aggcgtcttc gaatccatca tccaatgatg cgcaagcttt tgaatatttt ggttgatcga
    25441 tataatcatg aatcaatcga tttttagcct cacgcgctaa gttaatatct gtgaacttaa
    25501 aaattccttt aacagcttct ctgaaagatt ttgaattttt tttaggaatg gtggtaaaga
    25561 tatttcttag gaagtgaact tggcatcttt gccaacttac gttggtgaag gattttctaa
    25621 tggcagagac taatcctttg tgcgcatcag aaataacgag ttccgtacct tgtaaaccgc
    25681 gttcttttag gtattcaaaa aatgttgtcc aggtctcttc gctttcgcca ctttgaatca
    25741 tgaagccgat aatttcacgg tcgccatctt tggttattcc aatcgctata tgacagcttt
    25801 ttgagagtac tcgattttct tctcgtactt ttatatagag tacatcggtc attaagtaag
    25861 gataattttt ttctgataat aaacgattct gccactcgtt aaccataggt tctagctgtt
    25921 ctgttaagct agaaacgaag gacttagaga cggatttacc acaaagttct tccacaattt
    25981 ttgatacttt acgagttgaa acgcctgata catacatttc caacattgaa gccatgaggg
    26041 ctttttcgtt tcgttgataa cgttcaaaca ctgtgggtga aaaatggcca tcacgtgttc
    26101 tgggtacttt taattctagc gtgcctacac gtgtcgtaaa gctgcgctca taatagccat
    26161 ttcgttgact ttgtcggttt tctgttcgtt catattcttt tgcttgaata tattctgttc
    26221 gttgattttc cattagttga ttaaataccg ttgttaaaat atttttagaa acgtcatcct
    26281 ttacagaata ttcaataatg ctttgaatct cttcgctttt cagtgtaaaa tgtacttggg
    26341 tcatgtaaaa gtcctcctgg gtatgttttt gtcgttaaaa acattgtacc gtaaaaggac
    26401 tgttatatgg cctttttact tttacacaat tatacggact ttatctaagt ttcacttgga
    26461 tgcaaggttt aaaactagta gctgtcgcta ttgtaggcca agctattata ggaatgggca
    26521 aaaaattaac aaataccaaa accactattg cactagcatt atttgttctt atattatcgt
    26581 tagtaataaa taatctttat atacaagtca ttgcactatc aataactggt gtatatggtc
    26641 tcatctttct aaaacaaact tcaacagata aatctaaaat aaaaaacaaa tcatttaagt
    26701 tacctaaaaa gttaggtttt gtttcattat cattattctt tttactatta actgtattac
    26761 ctatcgctag ttctatgaca aataatctat ggttaaaaat gtttgatagt ttttatagat
    26821 caggttcctt agtttttgga ggaggacatg ttgtcttacc tttattaaaa aatgagtttg
    26881 taccatcagg attaatatca cccgataact tcataacagg ttatgctgct gctcaagctg
    26941 tacctggacc attatttacg tttgcttcat atattggtat gtctatagaa gggattggag
    27001 gagcaatttt ggctactttt gctattttcc taccagcatt tcttttattg tttggaattt
    27061 tgccattctg ggataatatt aaatctaaca tttatgctga agggttttta aaagggataa
    27121 gtgcaggtgt agtcggtatc cttattgcag ctttttataa tcctatttgg acttcaacga
    27181 ttaaatcaga attagatttt actttagcca gctcattatt catattgtta atgtatttta
    27241 gatttccttc ttgggctatt gtcttgatag gtattatctt aggtattcta ttttattaat
    27301 ataaattaat ggatataaat aataattgaa atacttatat tctatacggg gctgagacat
    27361 aaattccaag ctccttatct cttcaaaaca attttttcga aaaattaaca taaattatga
    27421 ttatcagaag tacgatccac ataaaaagca cgataagttt ttaaacttat cgtgtccttt
    27481 ttaattacag ttagttacca aacaaacgac tccaaaaccc ctttttaggt gattcttcct
    27541 ccctatcatc aggttcgctc tttattgctt ctgttagttt agcatctttt agtaattcat
    27601 cttcttttat acttttattc ttattctttt cagaaatatc tttatgctca gtttctgttg
    27661 gttttttctt ttcttgttgt tgagccctat tttgatttcc ctcagtaaat actgcttctt
    27721 gcatattaac gttttgttta ttattagtct tctcaatatc aaaagaatag ttaagctgtc
    27781 tttcttcttc taattgattt tctagttttt gaatcttttt attactttcc aaagctaaaa
    27841 tttgttgatt ttctaaaagt ctattaagag tatttatttg ttctttatct ctatttgatt
    27901 gttctttata tatatctaac tggttatata aatgttttat tgtttcatct tttaccaggt
    27961 tattactatt agtcttaact tcttctttct tttcattttc aaaatcatta tgtttatttt
    28021 gattttttct tattcggttt actactataa tttcatcttc acttgctaaa taatttacat
    28081 tgtcaacctt ttggaatttc acattcgctt ttttagcatt attataaaca gtcattttcg
    28141 taacattcaa ttcatcagca atctctttca tactcttcat ataatgtcct ccatatagtt
    28201 atacacataa cacctatatc attatatagt ctttatactt gttaatacaa cattatatat
    28261 atattcaagt aatcttatat atatagttat acgtaaacac tatatatcta catttatata
    28321 ggcttatata gcctttatac ttgttatata ggtgtttata tagttctata caacttattc
    28381 atataatgtc attatacgaa attctaacat tctttgaaaa tgcatacata caaatgtata
    28441 taaacaattt aacaaaactt tcaaaagtgt taatataagt atatataaaa gaaacccgac
    28501 tacgggaata gtcaggtttc ttcggtaata aaacaagtgg tttgtttgtt tatataattg
    28561 ttatattctt attatatata ttaagaatta ttagtgcaag ccgaacacat ataaacttac
    28621 ttatagctta tttattacct cttttaaaat tcatatgtga aagaggtttt ttgt
//
