LOCUS       NZ_CP129261             6675 bp    DNA     circular CON 13-JUL-2023
DEFINITION  Escherichia coli strain STEC1587 plasmid p_STEC1587_2, complete
            sequence.
ACCESSION   NZ_CP129261
VERSION     NZ_CP129261.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN36269290
            Assembly: GCF_030413765.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6675)
  AUTHORS   Sui,X. and Yang,X.
  TITLE     Prevalence and Characterization of Shiga toxin-producing Escherichia
            coli isolated from asymptomatic carriers in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6675)
  AUTHORS   Sui,X. and Yang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2023) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, NO.155 Changbai Road, Changping District, Beijing
            102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/13/2023 02:10:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,077
            CDSs (total)                      :: 4,954
            Genes (coding)                    :: 4,768
            CDSs (with protein)               :: 4,768
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 67 of 186
            Pseudo Genes (incomplete)         :: 107 of 186
            Pseudo Genes (internal stop)      :: 49 of 186
            Pseudo Genes (multiple problems)  :: 38 of 186
            Pseudo Genes (short protein)      :: 3 of 186
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP129261.1.
            Bacteria and source DNA available from China CDC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6675
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="STEC1587"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p_STEC1587_2"
                     /geo_loc_name="China: Guangxi"
                     /collection_date="2021"
     gene            complement(147..470)
                     /locus_tag="QYF42_RS25300"
                     /old_locus_tag="QYF42_25300"
     CDS             complement(147..470)
                     /locus_tag="QYF42_RS25300"
                     /old_locus_tag="QYF42_25300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_001444404.1"
                     /translation="MLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPSKTSGLPTL
                     APPLLRQFASVGNNLNQIARKINSGQWSGHDRVHVVAALMAIGRELSELRDEVRKQGER
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            538..729
                     /locus_tag="QYF42_RS25305"
                     /old_locus_tag="QYF42_25305"
     CDS             538..729
                     /locus_tag="QYF42_RS25305"
                     /old_locus_tag="QYF42_25305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165980.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADDQADICEALHDHA
                     DELYRSCLARFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(881..1069)
                     /locus_tag="QYF42_RS25310"
                     /old_locus_tag="QYF42_25310"
     CDS             complement(881..1069)
                     /locus_tag="QYF42_RS25310"
                     /old_locus_tag="QYF42_25310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001479923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_024177148.1"
                     /translation="MDNTITAFEWADTARRSRTTERSESVSEEAEKRLDEHFLLTHLCG
                     ISHPAWCTFHTILTDAT"
                     /name="hypothetical protein"
     gene            complement(1776..1922)
                     /locus_tag="QYF42_RS25315"
                     /old_locus_tag="QYF42_25315"
     CDS             complement(1776..1922)
                     /locus_tag="QYF42_RS25315"
                     /old_locus_tag="QYF42_25315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711480.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_000726755.1"
                     /translation="MKKKIGGSMILVLAVLCLTACQANYVRDVQGGTIAPSSSSKLIGV
                     AVQ"
                     /name="colicin release lysis protein"
     gene            complement(1992..2255)
                     /locus_tag="QYF42_RS25320"
                     /old_locus_tag="QYF42_25320"
     CDS             complement(1992..2255)
                     /locus_tag="QYF42_RS25320"
                     /old_locus_tag="QYF42_25320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488334.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin immunity domain-containing protein"
                     /protein_id="WP_001038407.1"
                     /translation="MNKMAMIDLAKLFLASKITAIEFSERICVERRRLYGVKDLSPNIL
                     NCGEELFMAAERFEPDADRADYEIDDNGLKVEVRSILEKFKL"
                     /name="colicin immunity domain-containing protein"
     gene            complement(2252..4345)
                     /gene="cda"
                     /locus_tag="QYF42_RS25325"
                     /old_locus_tag="QYF42_25325"
     CDS             complement(2252..4345)
                     /gene="cda"
                     /locus_tag="QYF42_RS25325"
                     /old_locus_tag="QYF42_25325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-D"
                     /protein_id="WP_001286654.1"
                     /translation="MSDYEGSGPTEGIDYGHSMVVWPSTGLISGGDVKPGGSSGIAPSM
                     PPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAART
                     VLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGN
                     NVPVKYRLMDLMQNGTQYMAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNL
                     PDLVLSVGQMNTPVLSNPEIQEEGVIAETGNYVEAGYTMSSNNHDVIVRFPDGSGVSPL
                     YISTVEILDSNGLSQRQEAENKAKDDFRVKKEEAVARAEAEKAKAELFSKAGVNQPPVY
                     TQEMMERANSVMNEQGALVLNNTASSVQLAMTGTGVWTAAGDIAGNISKFFSNALEKVT
                     IPEVSPLLMRISLGALWFHSEEAGAGSDIVPGRNLEAMFSLSAQMLAGQGVVIEPGATS
                     VNLPVRGQLINSNGQLALDLLKTGNESIPAAVPVLNAVRDTATGLDKITLPAVVGAPSR
                     TILVNPVPQPSVPTDTGNHQPVPVTPVHTGTEVKPVEMPVTTITPVSDVGGLRDFIYWR
                     PDAAGTGVEAVYVMLNDPLDSGRFSRKQLDKKYKHAGDFGISDTKKNRETLTKFRDAIE
                     EHLSDKDTVEKGTYRREKGSKVYFNPNTMNVVIIKSNGEFLSGWKINPDADNGRIYLET
                     GEL"
                     /name="cda"
     gene            4609..4854
                     /locus_tag="QYF42_RS25330"
                     /old_locus_tag="QYF42_25330"
     CDS             4609..4854
                     /locus_tag="QYF42_RS25330"
                     /old_locus_tag="QYF42_25330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000820629.1"
                     /translation="MKRHRLTEAEERRLAEAIAAEARAMGLTKKDKMPQETKRRLRARI
                     LKAILDERTASKNREATLTAGQDPDDTFTWQPLRRR"
                     /name="hypothetical protein"
     gene            complement(5344..5577)
                     /locus_tag="QYF42_RS25335"
                     /old_locus_tag="QYF42_25335"
     CDS             complement(5344..5577)
                     /locus_tag="QYF42_RS25335"
                     /old_locus_tag="QYF42_25335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137424.1"
                     /translation="MTELEMHLLNALEQLQQDYTQRLKDWESAFTDLQHMFELTRQENG
                     QLREQCDDLSQQVLRLAGQVDRLSRLFITNSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(5584..6144)
                     /locus_tag="QYF42_RS25340"
                     /old_locus_tag="QYF42_25340"
     CDS             complement(5584..6144)
                     /locus_tag="QYF42_RS25340"
                     /old_locus_tag="QYF42_25340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_001345151.1"
                     /translation="MSNLLQMGTDFEKKLKERAVSTENMLNSEFRKLEASVDRELNLNG
                     QKIRDAISAHTAAVKEQLETLNSAVNAQFSATENELARRQEELLWKLVKGRILYPSLTA
                     LCVTVGIFLASWGLIQWQESRIAANILAIRDQEETLAKLREKTWGVTYHEGRNGKFLVL
                     PSGVKGENNWTVEKKNAVRLVRE"
                     /name="MbeB family mobilization protein"
     gene            complement(<6176..6589)
                     /locus_tag="QYF42_RS25345"
                     /old_locus_tag="QYF42_25345"
                     /pseudo=""
     CDS             complement(<6176..6589)
                     /locus_tag="QYF42_RS25345"
                     /old_locus_tag="QYF42_25345"
                     /inference="COORDINATES: protein motif:HMM:NF015397.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     BGC             1..6675
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(815..898)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="96.0"
                     /evalue="1.15e-36"
     Typing          complement(1360..1547)
                     /name="rep_cluster_2401"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.296"
                     /coverage="100.0"
                     /evalue="2.18e-82"
     Typing          complement(151..578)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="88.811"
                     /coverage="100.0"
                     /evalue="9.59e-78"
     Typing          complement(5238..6673)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.582"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 attttttcgc aaacggcgtg gcatcgatga gttcccgcac ctcttcggga gcaccccgca
       61 gaactctcgc cccttcccgg ttacgctccc ggcccagcag gtaatcaacc ggaccactgc
      121 caccgccttt tcccctggca tgaaacttaa ctatcatcgc gttctccctg tttacggacc
      181 tcatccctca gctcactcag ttcacgtccg atggccatca gtgcagccac cacatgaacc
      241 cggtcatgcc ccgaccactg tccactgttt atcttccggg ctatctgatt caggttattg
      301 ccgaccgaag cgaactggcg caacagcggc ggtgccagtg tcggaagacc tgacgttttc
      361 gatggcggtg cccccaggca gaccttacgc atccatgacg caagttgttt tccctcacaa
      421 cgtgccagca gccgcgcatg ttcctcatcc gtgacccgta tcgtgagcat cctttcgcgt
      481 ttcaccggta tcattaaaaa cctccgacag actccccaca catggagaaa cagaactgtg
      541 actaaacagg aaaaaaccgc ccttaacatg gcccgcttca tcagaagcca gacgctgacc
      601 ctgctggaaa aactgaatga actggacgcc gacgaccagg ctgacatctg cgaagcgctt
      661 cacgaccacg ctgacgagct ttaccgcagc tgcctcgcac gcttcgggga tgacggtgaa
      721 aacctctgac acatgcagct cccggagacg gtcacagctt gcctgtgagc ggatgccggg
      781 agcagacaag cccgtcaggg cgcgtcagcg ggttttagcg ggtgtcgggg cgcagccatg
      841 acccagtcac gtagcgatag cggagtgtat actggcttaa tcatgtggca tcagtgagga
      901 tggtatgaaa agtgcaccat gccgggtgtg aaatgccgca cagatgcgta aggagaaaat
      961 gctcgtccag gcgcttttcc gcttcctcgc tcactgactc gctacgctcg gtcgttcggc
     1021 tgcggcgagc ggtatctgcc cactcaaaag cggtgatagt gttatccaca gaatcagggg
     1081 ataacgccgg aaagaacatg tgagcaagaa acgaaaaccc cgaaaaaggc cgcgccggag
     1141 gcgctttttc cataggctcc gcccccctga cggacttcac aaaacagaca ctttttcggt
     1201 gcatctgtgg gagccgtgag gctcaaccat gaaatccgcc agcggtggcg aaacccgacg
     1261 tggcttaaag atcatcaccg tttccggtga atcgctccct cctgcgcccc cacgttcccg
     1321 ccatatcgat taccggatac cttttccgcc tttctccctt gcgggacacg tggcgctttc
     1381 tcatagctca cgtcttctgg tatctcgggg cgacttaggc agttcgctcc gggctgggct
     1441 gtatgcagga accccccgtt cagcccgact gctgcacctt ctccggtaac tgttctcttg
     1501 gggccaaccc ggaaaagaca cgacttaacg ccactggcag cagccattgg taactgattt
     1561 agaggagttg ctcttgaagt tatgaaccag ttaaggctaa actgaaaaga cagttttggt
     1621 gactgtgctc ctccaagcca gttaccaccg ccgattagaa gaggtcgaag acttctgatc
     1681 ggacggaagg acccgccaca aggcgggttt tttcgtttac aggcagcaga ttacgcgcag
     1741 aaaaaaagga tctcaagaag atcctttaat atttttcact gaaccgccac cccgattagt
     1801 ttcgaagatg atgatggagc aattgttcca ccctgaacat cccttacata gttagcttgg
     1861 caagcagtca gacacaaaac agcaagaacg agaatcatag atccccctat cttttttttc
     1921 atgacatctc cttgtcatga gtgaatatct gacatttata cttaaatgcc agatattaaa
     1981 atcactcatg attataattt aaatttttcc aagatagatc ggacctcaac cttaagtcca
     2041 ttatcatcaa tttcataatc agccctatct gcatcaggct caaatcgctc agcagccata
     2101 aacaactctt ccccacaatt taatatattc ggagacaaat ccttaacacc atacaatctt
     2161 ctccgttcaa cacaaattcg ctctgaaaac tcaattgctg taattttcga agctaaaaat
     2221 aatttcgcca aatcgatcat tgccatcttg ttcatagttc acccgtctct aaataaattc
     2281 gaccattatc cgcatctgga tttattttcc acccagataa gaactcacca tttgacttaa
     2341 ttataaccac attcatcgta ttaggattaa aataaacttt tgaacctttt tctcttcggt
     2401 atgttccttt ctctactgta tccttatccg ataaatgctc ctcaatagca tccctgaatt
     2461 tagtaagagt ttcacgattc ttttttgtat cactaatacc aaaatcacca gcatgtttat
     2521 attttttatc aagttgttta cgcgaaaatc gccctgaatc cagaggatca ttaagcatca
     2581 cataaacagc ttcaacacca gtcccagcag catcaggacg ccagtaaata aaatctcgta
     2641 gtccaccaac atcagaaaca ggagtaatcg tcgttactgg catttcgacc ggttttactt
     2701 ccgttcctgt atgcactggt gtaaccggaa cgggttgatg attacctgta tctgttggca
     2761 ccgaaggttg tggtaccgga ttaaccagaa tcgtccggga aggtgcgcct actactgctg
     2821 gtaacgtgat tttatccagt cctgttgctg tatcacggac agcattaaga acaggaaccg
     2881 cagctgggat actttcattc cctgttttca gtaaatccag agctaattgc ccgttactgt
     2941 ttatcaattg tccacgaaca ggcagattta cactcgtcgc accaggttca atgaccacgc
     3001 cctgtccagc caacatctga gcactcagcg aaaacatcgc ctccagattt cgccccggca
     3061 cgatatcact tcctgctcca gcttcttctg aatgaaacca cagagcacca agagaaatcc
     3121 gcataagcag gggactcact tcgggtatgg ttactttctc cagagcatta ctgaaaaact
     3181 tgcttatgtt gcctgcaata tcaccagcag cagtccagac accagttccg gtcatcgcca
     3241 gttgtacaga actggcagtg ttattcagaa caagagctcc ctgctcattc attactgaat
     3301 tagccctttc catcatttcc tgtgtatata caggaggctg gttcacacct gctttactaa
     3361 ataactcggc ttttgctttt tcagcttcag cccgggctac cgcttcttct ttcttgactc
     3421 tgaaatcatc ctttgcttta ttttcggctt cctgacgctg actcagacca ttactgtcca
     3481 gaatctctac agttgaaata tataacggag aaacaccact gccatcagga aaacgaacaa
     3541 tgacatcatg attattactg gacatcgtat aaccagcctc aacataatta cctgtctcag
     3601 caataactcc ttcttcctga atttcgggat tagacagaac cggagtattc atctgaccca
     3661 cacttaatac caggtccggt agatttggtg atacaggggc actgtaaaca tctttaatat
     3721 ttgttcccgg acgactccgg tccggaactg gaacggcatc aactaccggc actgtcatcg
     3781 gaatacctcc gataatagcc atatattgcg taccgttctg cataaggtcc atcagacgat
     3841 atttcaccgg tacattatta cccgctgctg gtaactggct ggccggaata tccgttacct
     3901 gttccagttg ctgtgtaacc ataagacgaa taattttttg ctcatttccg gaagcaggct
     3961 ccagacgggc aaaagaaaca gcagccgggc gagacggttc tggcaaacca ccacgtaaac
     4021 cattctcaag aactgttcgt gcagcggaaa ctttctcgtt tccccaaggg ctatgcacac
     4081 tgacagacca tcccgaccag tctccctctt caagttcctt atccagaata atccggcgaa
     4141 taattcccgg aaaaagaaca ctttgtacaa gtgcgatacc ctgtgggctg taatcccccc
     4201 atcccggagg catggatgga gcgatacctg atgagcctcc tggtttcaca tcaccacccg
     4261 aaatcagtcc tgttgacggc cacacgacca tcgagtgccc ataatcaata ccttctgtcg
     4321 gaccactacc ttcgtaatca ctcataaaaa cacctctttg acttttaaaa caatgcgtta
     4381 aaaacaacaa actgtacata aaaccactgg ttttatgtac agtaaaaagt tacgtcacct
     4441 cgtaaatcct gtcaacccac tggatttacg tttttgtgaa aacgctcaag aaaaacaacc
     4501 aatcattctt aaactcaatg gcaacaggca tgaaagaagg ctgattagca taaggagaga
     4561 gccaacagtt aaactgttat gacaccagag aaacacccgg agaccaccat gaaacgccat
     4621 agactgaccg aagccgaaga gcgccgactg gcagaagcca ttgccgctga agctcgtgcc
     4681 atggggctga cgaaaaagga caaaatgccg caggaaacaa agcgacgcct ccgggcacgg
     4741 atacttaaag ccattcttga tgaacgaacg gccagcaaaa atcgagaagc cacactgact
     4801 gccggacagg acccggatga caccttcacc tggcaaccac tgcgccgccg ctaagctaag
     4861 ggttatttaa cataacccct tattgtacgc accgctgaaa tgcgttcagc gcgatcacgg
     4921 ctgctgacag gtaaaaatgg caacaaacca cccgaaaagt tgccgcgatc gcacctgata
     4981 aattttaacc gtatgcatag ctattcagcc atgtgaataa cgctggtttt gcctgcgtaa
     5041 acctcatgac actgtttttt ttccatcttt tcagttgatg acatacgcag acatcgcggg
     5101 atgaggctga ggaatgagcg cgatctggca aagaggcaaa acacagcaac aaaaacgaca
     5161 cgccagaatc gcgcccggat gcgtttttaa cgcgttccgg taccatctgg caacctcccg
     5221 gaacaactca ccgtcacatc cccattgacg ggccacgcca tacccgtgct tcccgttcct
     5281 gctcttcatg ccaggaccgc gcacgctccc gttccaggcg tgcctgcctt tcctgttcat
     5341 cccttatctg ctgttcgtga taaataaccg actcaagcgg tccacctgcc cggctaatct
     5401 cagcacctgc tgactcaagt cgtcgcactg ttccctcagt tgcccgttct cctgtcgtgt
     5461 cagctcgaac atatgctgca aatccgtgaa ggcgctctcc cagtctttca gccgctgcgt
     5521 atagtcctgc tgcaattgct ctaaggcgtt cagtaagtgc atttccagct ctgtcatact
     5581 cacttactcc ctgaccagtc ttactgcgtt cttcttctcc accgtccagt tgttttcccc
     5641 cttcaccccg gacggcaaca ccagaaattt cccgttcctg ccctcgtgat acgtcacacc
     5701 ccatgttttt tcccggagtt tcgccagcgt ctcttcctgg tccctgatag ccaggatgtt
     5761 cgccgcaata cggctttcct gccactgaat cagcccccat gacgccagaa aaatcccgac
     5821 cgtgacgcaa agcgccgtca gcgacgggta cagtatccgc cctttgacca gcttccagag
     5881 cagctcttcc tgccgccggg caagttcgtt ctctgtggcg ctgaactgcg cgttcacggc
     5941 actgttcagc gtctccagtt gttctttcac cgctgctgtg tgtgcgctga tagcgtctct
     6001 gattttctgc ccgtttaagt tcagttccct gtctacagac gcttcgagct tcctgaactc
     6061 gctgttcagc atgttctctg tagagacggc acgctctttc agtttcttct cgaagtctgt
     6121 ccccatttgt aaaagattgc tcatacagcg cccctttcag cctgagatta cgcccgccct
     6181 ccgggtcggc gatactgata ctgctcctgg ttgtcctcac cacctcaaaa cctgccgctg
     6241 taagcgcctc agtgacatcc tgacgcgttt ttagcgctcc ggcatggtaa agagcctcca
     6301 gtcccctcgt aatcgcttct gcggcctcct gtttcgcttt cggcagatta ttcggggtga
     6361 caagtgtccg cctgttctcc ggtgcgttcg ggtcgtgcag cccgtaatgg tgattcacca
     6421 gtgtctgcca ggcattgatt cgcggacggt ccgcccggtc gtaatagggc tggagccgtt
     6481 ttccgctcgc cagctccata ttcgggatga caaaattcag ctcaagacgc cccttgtcct
     6541 ggtgctccac ccacaggatg ctgtactgat ttttttcaag accgggcatc agtacccgct
     6601 caaagctctc catcaccctt tcacgctctc ccggtggcag tgtctgctct gcaaaagaca
     6661 gaacccccga ggtgt
//
