LOCUS       NZ_CP128620            13810 bp    DNA     circular CON 05-JUL-2023
DEFINITION  Enterobacter roggenkampii strain WL374 plasmid pWL374-2, complete
            sequence.
ACCESSION   NZ_CP128620
VERSION     NZ_CP128620.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35977203
            Assembly: GCF_030384865.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter roggenkampii
  ORGANISM  Enterobacter roggenkampii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 13810)
  AUTHORS   Jiang,T.
  TITLE     Complete genome sequence of a carbapenem resistant Enterobacter
            roggenkampii isolate WL374
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13810)
  AUTHORS   Jiang,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2023) Department of Clinical Laboratory, The
            Affiliated Wenling Hospital, Chengxi, Wenling 317500, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/04/2023 08:17:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,950
            CDSs (total)                      :: 4,829
            Genes (coding)                    :: 4,750
            CDSs (with protein)               :: 4,750
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 27 of 79
            Pseudo Genes (incomplete)         :: 53 of 79
            Pseudo Genes (internal stop)      :: 12 of 79
            Pseudo Genes (multiple problems)  :: 12 of 79
            Pseudo Genes (short protein)      :: 1 of 79
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP128620.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13810
                     /organism="Enterobacter roggenkampii"
                     /mol_type="genomic DNA"
                     /strain="WL374"
                     /host="Homo sapiens"
                     /db_xref="taxon:1812935"
                     /plasmid="pWL374-2"
                     /geo_loc_name="China: Wenling"
                     /collection_date="2021"
                     /collected_by="JT"
     gene            149..1447
                     /locus_tag="QU521_RS24600"
                     /old_locus_tag="QU521_24600"
     CDS             149..1447
                     /locus_tag="QU521_RS24600"
                     /old_locus_tag="QU521_24600"
                     /inference="COORDINATES: protein motif:HMM:NF017116.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="WP_182410916.1"
                     /translation="MNTQDNVMPIEEAKALKEASDAIGKVIADLEKNDSGLDKGRIRNS
                     TRNLARIIENARLLLGFSAHYDEFLLETVLLSDKGRRPLDADAVTDVMRMLTDHEFRPY
                     AKPKSSMYSIIQEPDRERLKHVIKAVARLNAIDSLRDWFCSLPEWDGVERVDRFFGHYV
                     PCNDNPVYMAAVSRYFLTSLAGRAVCPGLKADAIPVLYGPQGTRKSTMLEAIAPDFNWY
                     ANTEIDGENKEVVRQRIGKMIVEYAEMDKMRPSDVQKIRRDLALRKDENRRMKQDYYDQ
                     VPRRWMGCGTVNSQKFLVDETGNRRFFPLTVTDKCLIDKFTSDREQVFAEALNIFNAEG
                     NVPSWLTAEELAKAAHEDYIDHDPWHGTIEMLLQSHPSQISNRLLNEAVGLDVGRRDKK
                     SAHRIRAIMTMLGWSEAKNIGPNKERGFRRNLP"
                     /name="VapE domain-containing protein"
     gene            complement(1963..2418)
                     /locus_tag="QU521_RS24605"
                     /old_locus_tag="QU521_24605"
     CDS             complement(1963..2418)
                     /locus_tag="QU521_RS24605"
                     /old_locus_tag="QU521_24605"
                     /inference="COORDINATES: protein motif:HMM:NF017834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_289784023.1"
                     /translation="MQPPSRRAIQARALRAEGLTIPQIAEKMGCNRGTVSKWLAKDITK
                     AQASGLDQLISAAQAKYDSLPPSEAERLSQLRDTLREQQQVIIKRQIKLLESVQGEAMT
                     ALRSKDLPTVRAAASLISALTRAFAHEAMVYQIIDPAEVMRQALKDD"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(2607..2969)
                     /locus_tag="QU521_RS24610"
                     /old_locus_tag="QU521_24610"
     CDS             complement(2607..2969)
                     /locus_tag="QU521_RS24610"
                     /old_locus_tag="QU521_24610"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063613592.1"
                     /translation="MKINIPVALTLLLASTQLHAGEIASRFLCTDGTIIRLETNTGPRM
                     TVTWNGNRFPVRELTSESYGVHITAGVPQQTIAMMDIFWLDGGNRKFFATFSTSLKADS
                     VSVECSHDLGSNRLQF"
                     /name="hypothetical protein"
     gene            complement(3030..3221)
                     /locus_tag="QU521_RS24615"
                     /old_locus_tag="QU521_24615"
     CDS             complement(3030..3221)
                     /locus_tag="QU521_RS24615"
                     /old_locus_tag="QU521_24615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_103850879.1"
                     /translation="MIVASQRHPAQFPGLTIEHGEIRQHGIQRTIAMNGRGIHQTSLRT
                     AEGKVITLPVCRLFDWQA"
                     /name="hypothetical protein"
     gene            complement(3330..3893)
                     /locus_tag="QU521_RS24620"
                     /old_locus_tag="QU521_24620"
     CDS             complement(3330..3893)
                     /locus_tag="QU521_RS24620"
                     /old_locus_tag="QU521_24620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016151785.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_289784024.1"
                     /translation="MIFGYVRVSTAEQNLGGQIDAILQRYPDARILSDEGVSGITPVME
                     RPGFSALMKVAGSGDVIVVAAIDRIGRNAVSTLEVVEDLKAKGITLISLREGFDATTPA
                     GKLMLTMLAGIAEMERTSMLERQRAGIDSAKKEGKHLGRPIKVTPELRKKILEKREIGI
                     PAARIARDLNISRASVFRVFKEES"
                     /name="recombinase family protein"
     gene            4108..4746
                     /locus_tag="QU521_RS24625"
                     /old_locus_tag="QU521_24625"
     CDS             4108..4746
                     /locus_tag="QU521_RS24625"
                     /old_locus_tag="QU521_24625"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_130944506.1"
                     /translation="MTNSNAAQVDNQLSLIEDALGKYAAPLPQIQSPDLIREQAVDLLN
                     RADVLESNADELRTELQNREQVVHDIDRQLATLVGLVEEGKACLRSGEPVRPECAMAHS
                     LIPEVENELSLARNAASAANGQLLAVTNQIDTLRSQYARMIGQVALDARMAHVQALLDT
                     AMQQAAELGLELANNHQFSAAIRVDNRLAILGRNNGMLSSLRNYQGSSR"
                     /name="hypothetical protein"
     gene            4746..5327
                     /locus_tag="QU521_RS24630"
                     /old_locus_tag="QU521_24630"
     CDS             4746..5327
                     /locus_tag="QU521_RS24630"
                     /old_locus_tag="QU521_24630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_289784025.1"
                     /translation="MTIKAVLAQLAALNSTMTKSHAGNDTGREARLNFEDHKLIGDCWQ
                     AKVSSAQIEELKKSLKATHDLPDADRKAAFSAVRQYLLKSTAGDALEQAMSGSPVQFAP
                     DMTVKRNMSTEQIHLARQQQISDQQLIRDCEVAGVATGQIVELAARLEDTRGLPNNIRQ
                     PGIDAVRQQLTQAQPSPAEQGIDWSAQGWK"
                     /name="hypothetical protein"
     gene            5318..5686
                     /locus_tag="QU521_RS24635"
                     /old_locus_tag="QU521_24635"
     CDS             5318..5686
                     /locus_tag="QU521_RS24635"
                     /old_locus_tag="QU521_24635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_289784026.1"
                     /translation="MEINSRAVLLACLSALRLPEGERTSDHVMQLAHLRTVLRNEGYSS
                     PAIHDDAALLKEAEGLAKARREWLADSADMRQRHAELQHLVALNLLPEDEARQEQGDNY
                     REHQLRDPVKQEGKPEYD"
                     /name="hypothetical protein"
     gene            complement(5901..8651)
                     /locus_tag="QU521_RS24640"
                     /old_locus_tag="QU521_24640"
     CDS             complement(5901..8651)
                     /locus_tag="QU521_RS24640"
                     /old_locus_tag="QU521_24640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase"
                     /protein_id="WP_289784027.1"
                     /translation="MAIKIPVSAQFDAADLKQQIQMVNDQIRILASQVGQANKQKFEPI
                     NVKSKDDLNAFIKQMQKLLSIQTELKQTMSKTGQGATNPLMADWSKMYTDQAVRIKKMQ
                     SMLQFLGVEFNDQPAPKPKLPAPTPSNPSPAPQSGPQNNNQPPAWQNHLSTMLRNAGPV
                     GGTISGAMNAGLSGGAGAGLMGLVGGLAALGVGKIIGAVADKIGQAQDNVIGLDKLYRQ
                     MGGIVSFSSLQRGVMSTANNLGMTNGDAIALASTYSRAANIQPGQNLGTGMLVSGGLAR
                     SYGLDPNSVAGTMGQLSASRVVNNDQQLRRMGLLMGEAIGKSGAFAQAGEAMQAISDFA
                     TQQARASLTAPNVPGYAGAMAGLMSSGIPGMDLQGSTNLLSRVNANLQRGGAMGEPSRA
                     FMARMAMRNGINNPMALEVLQSGGAFGTISSTLGPDTLYGQRFGGNHHGDQTLLDMTRQ
                     GIHRAYGYGPDSVAALSRHLGVSINDALAIDQMSSADMSGVSSRLSRLKINPNSVNATS
                     YAALGQIQSGKGLESMGNEYLKRGGLDAGERQRLTDALKGTDPEKLKDVLTQVATVHGP
                     AKTEGSEIRDNVAKLNNQFEDYARRALPALDVMRMALVKMTGGSEDSLRRDYEKGMRLD
                     TQQQARRKYGWRLDAYQQEMNTLQDKGVGMQTAGPEGDRYRALKRQQQLMRQQQLNFVE
                     QGNANAHAAAYGPQTAGEAALDSNYISSPSAAAAGSGAAGNWAGGNVGNLKDVNGNWRR
                     FPSQQAGIAASAGQLLRYSTGAFKGGRKRTLREIVSTYASGDPEVPRYIRQASEWTGYG
                     PDQQLDLTDQNTLLNVTRAILRKENVKNASIPQSVVTEGVNMALNNQNNYKIAPETMPA
                     GQRGGKIDISDANINVNLQYPDGRTQTQSVPVKSSFTQPRSFASR"
                     /name="lytic transglycosylase"
     gene            9253..10488
                     /locus_tag="QU521_RS24645"
                     /old_locus_tag="QU521_24645"
     CDS             9253..10488
                     /locus_tag="QU521_RS24645"
                     /old_locus_tag="QU521_24645"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_289784022.1"
                     /translation="MTGKNDWLLIPNLLDEALARTPAPSCGGGFEIWKRDITGIMCWLR
                     YLSRDAEAVNVCTRWSEEPGITPAQRSNNASLFSSTARYVLSLPPDTAKAYAIGLLYRA
                     PGLVDDIQTGRFGAEYQPTAEQLRQQEAQREARQQEFEARQQEQELATQKQRQKAYADA
                     MRIYGKSNADPDAVRATPYWREKEKAAGFPLPVPEGIRCGSPRMFLPVVGPVYWNNSVI
                     VPLHVISEYLQLGHVSIEVVCGTANPPASRTGDKRGLKGGLRQGAFFPINLDKARHNLP
                     LVIVEGLMTGIAVSLMTGGKLPIICAMSCEFFSNVIDELQIAYPVSPFYIIGDVGAGHR
                     KAADLATEKGRAEIYAVDLEPCLPEQEGADAFDMLARHGVDNGMVLLRSMFRTARLARG
                     DATVSPSSSVNP"
                     /name="AAA family ATPase"
     gene            10545..10847
                     /locus_tag="QU521_RS24650"
                     /old_locus_tag="QU521_24650"
     CDS             10545..10847
                     /locus_tag="QU521_RS24650"
                     /old_locus_tag="QU521_24650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008324014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228698703.1"
                     /translation="MSEQMPSPEMLDSLIFNHAADTASLLVSRGVCELDRLFGEGYAAA
                     NPVVLNQWVAVASTMQLAQLQINAANGLACQIERLGAMADAIEASAAAAYAGRMQ"
                     /name="hypothetical protein"
     gene            10844..11272
                     /locus_tag="QU521_RS24655"
                     /old_locus_tag="QU521_24655"
     CDS             10844..11272
                     /locus_tag="QU521_RS24655"
                     /old_locus_tag="QU521_24655"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032413484.1"
                     /translation="MSERVQQLITAELCSMIPKALAQWFREGGKSAGPEGPVIAFGKRI
                     KRGGVMTIVGRSIRGHLWATPAYYADAARIMRKDKRGKAYPSHCEIERETFTCQLLRQI
                     MSLTPAAYPGLPEAVPEWQTISEAEQRQIVETINACLR"
                     /name="hypothetical protein"
     gene            11282..11767
                     /locus_tag="QU521_RS24660"
                     /old_locus_tag="QU521_24660"
     CDS             11282..11767
                     /locus_tag="QU521_RS24660"
                     /old_locus_tag="QU521_24660"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061500276.1"
                     /translation="MQLDLFRQKGGMGLSEREAVEVARLRWHAFRRAFVGPPCPEFIRG
                     ARPACRVIPAAPPVVFIPEPEIEPELETLPEPSLEPESEEYDDFDIPDAIPLNTSQILA
                     SARYQIEAERLQSMGCYRRASNRYQKALTLAQPGKRADKLRAMVNRCARLAGKCVRE"
                     /name="hypothetical protein"
     gene            11882..12205
                     /locus_tag="QU521_RS24665"
                     /old_locus_tag="QU521_24665"
     CDS             11882..12205
                     /locus_tag="QU521_RS24665"
                     /old_locus_tag="QU521_24665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_045409922.1"
                     /translation="MAKTIELDKCTRCGGLTASAGFWAAIPGEQVGSTSQEVYLPIVAW
                     ASLGVEHRAVISGEHGLLYYAPIGCVTLRFDANMLDEQGNELCLTAAGDIGGAVYYVPI
                     ARA"
                     /name="hypothetical protein"
     gene            complement(12495..12956)
                     /locus_tag="QU521_RS24670"
                     /old_locus_tag="QU521_24670"
     CDS             complement(12495..12956)
                     /locus_tag="QU521_RS24670"
                     /old_locus_tag="QU521_24670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011899450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_024008463.1"
                     /translation="MAKNNYGINGSPNSHIAHPAGLPCFGSLPEFVSRGDVIPAGDIFL
                     RVGNHRGPNSGFGVRHIWAEHEKELVRLGYHTVNDVARFVCDVIQPGAGVYCEFNHPGG
                     KHRPKVLRSALGIVILEPKEADWAQSGWIYSVVTAYETHRTQGTLLGRL"
                     /name="hypothetical protein"
     gene            complement(12949..13440)
                     /locus_tag="QU521_RS24675"
                     /old_locus_tag="QU521_24675"
     CDS             complement(12949..13440)
                     /locus_tag="QU521_RS24675"
                     /old_locus_tag="QU521_24675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016155424.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_182410915.1"
                     /translation="MPQLSIRLPDDLVQLLDERASAEHLTRTDITAAALRAYLGVVPAP
                     AAADKLDRVIELLETIAGAPQRKTAAPQRQTVPDKSEMQRTTTPPNAPQRTTSDPRFQA
                     VDSEADALIVSLTQQRASLEDIVGALNAAGYRTATGGEWTRSRLRDYRHKLRDSGLLNG
                     "
                     /name="ribbon-helix-helix protein, CopG family"
ORIGIN
        1 gggaatactg agataactat acctgacggg catttgttac tcaacactga ttgtagcgtc
       61 aattttgacg ccattcaagc cgtattccct cgcaagatgc cccgccgtat cggccttaac
      121 gcaaaaaatt cgcagttaag gacataagat gaatacgcaa gataatgtaa tgccaatcga
      181 ggaagccaag gcgctgaaag aagcgagcga cgctatcggt aaagtgattg ccgacctcga
      241 aaaaaacgat tcagggctgg ataagggccg catccgtaac tccacgcgca acctcgcccg
      301 cattattgaa aatgcccgcc tgttactggg cttttccgca cattatgacg agttcctgct
      361 agaaaccgtc ctgctgagcg ataagggccg cagaccgctg gatgccgacg ccgtgaccga
      421 tgtcatgcgt atgcttaccg atcatgagtt ccggccttac gctaagccca aaagcagcat
      481 gtattccatc attcaggagc cagaccgcga gcgcctgaaa cacgtcatta aagccgttgc
      541 gcggctcaat gccattgact cgctgcggga ctggttttgc tcgctgcctg aatgggatgg
      601 cgtggagcgt gtggatcggt ttttcggtca ttatgtcccg tgcaacgata accccgtgta
      661 tatggcggcg gtgagccgtt atttcctcac ctcgctggca ggtcgcgccg tgtgccccgg
      721 attaaaggcg gatgccattc cggtgctata tggcccgcag ggcacgcgta aatccaccat
      781 gctggaggca atcgcgccag attttaactg gtacgccaac actgaaatcg acggggaaaa
      841 caaagaggtt gtgcgccagc gtatcggcaa aatgatcgtg gagtatgccg aaatggataa
      901 aatgcggcct tccgatgtgc agaaaatccg ccgtgatttg gcgctgcgca aggatgaaaa
      961 ccgccgcatg aaacaagact attacgatca ggttccgcgc cgctggatgg gctgcggcac
     1021 cgtaaactcc cagaaatttc ttgtcgatga aaccggaaac cgccgctttt tccccctgac
     1081 agtgaccgat aaatgcctga ttgataaatt tacctccgac cgtgagcagg tgtttgcgga
     1141 ggcgttgaat atcttcaatg ctgagggcaa cgtgcccagc tggctgacgg ctgaggagct
     1201 cgcaaaagcc gctcatgagg actatatcga ccacgatcca tggcacggca ccattgaaat
     1261 gctgctgcaa agccacccca gccagatctc caatcgcctc ctcaatgagg ctgtggggct
     1321 ggatgtaggc cggagagaca aaaaatcggc tcaccgcatc cgggcaatca tgactatgtt
     1381 gggatggtcg gaggccaaaa acatcgggcc aaacaaggag cgaggattcc ggcgtaacct
     1441 cccataaaca ggcgcatgag ccacctttcg aggtggcttt ttttatggag acgtggagac
     1501 aaaaggagac aaaaaggagg cataaaatag acgttttaac ttattgatat tattgaatat
     1561 agacgtaaga gacgtaataa atatatatta atataataaa ataccctata cagccacgcc
     1621 gccaccgcca gcagtaaaca acctctcgtt atgtctcctt acgtctctta cgtctatttc
     1681 ttttatattc aattggttgc gttgtctccc gtttagtctc tggagacgtt tatttgtctc
     1741 cgcctttgtc tccgctgccg catagcgtcg caaagtgcat ccccggaggg gtgcagctgc
     1801 gtgacgcggt tctgctgtaa tgggtgggat tgattgggat agtgcaaatt tggcaggcac
     1861 tgccgcagac gtgccggggt tgcctgaaat aaaaaaagat taacttttga gcaggtgctt
     1921 gcccttacgg ggaggggccg ggctgatcgc ccggcatggt gcctaatcgt ctttcagtgc
     1981 ctgccgcatg acctctgcgg ggtcaataat ctggtacacc atggcctcat gggcaaaggc
     2041 ccgcgtaagg gcggagatca ggcttgccgc tgcgcgaacg gtgggcaggt ctttgctgcg
     2101 gagtgctgtc atagcctcgc cctgcacgct ctccagtagt ttgatctggc gcttgatgat
     2161 gacctgctgc tgctcccgga gagtgtcgcg cagctggctg agccgttcgg cctcgctggg
     2221 tggcaggctg tcatatttgg cctgtgcagc gctgatcagc tggtcgagcc cgctggcctg
     2281 cgctttggtg atgtcttttg ccagccattt ggaaactgtg ccgcgattgc atcccatctt
     2341 ttccgcgatc tgcggaatgg tgagtccttc ggcgcgtagg gcacgggctt gaatggcgcg
     2401 gcgggatggt ggttgcatgg tgatgcctca aatgttgcca cgggttgccc atagtggcat
     2461 cacgactgct ttttggcggg cccagcccgc cgcctcccca ttgcctgcca ctggctcagc
     2521 ctgccagtcg cgacgctgtt aaacgaggcg tggtaatgcg ttggtacggc aaaaagaaag
     2581 cgccccgcag agaggcgctg aggaggtcag aattgcaggc ggttgctgcc taagtcgtgg
     2641 gagcattcca ctgatactga gtcagctttc agagaggtgg agaaggtcgc aaagaatttc
     2701 cggtttccgc cgtccagcca gaaaatatcc atcatggcga tagtctgctg tggcacgcct
     2761 gcggtgatgt ggacgccgta gctttcagag gttagttctc tgactgggaa tcggttcccg
     2821 ttccacgtca cagtcatgcg tggcccggta ttggtctcca gcctgattat ggtgccgtca
     2881 gtgcagagaa agcgggaggc tatctctccg gcgtgcagct gcgtgctggc gaggagtagc
     2941 gtgagcgcta cgggtatatt gattttcata atatgtaatt cattacacca tattgattat
     3001 gatatagggc ccccgcaggg gcccggtcgt tatgcctgcc agtcaaacaa gcggcacacg
     3061 ggcagagtta tcaccttgcc ctccgccgtt ctgagtgatg tctggtgaat gccgcgcccg
     3121 ttcatcgcta tagtgcgctg tataccgtgc tggcggatct ctccgtgctc gatggttaag
     3181 ccggggaatt gcgccgggtg acgctgtgat gctacgatca tttgtgtagt ccttctgtga
     3241 taggtcgggt tacaaggcgc ggttaaggtg gccacccgct ccgcgccgct ttcgggcctc
     3301 agctgttagc gcagctgggg cctgattctt tacgactcct ctttgaacac gcggaacacg
     3361 ctggcccggc taatgttcaa atctctggcg atacgtgcag caggtatgcc gatctcccgc
     3421 ttctccagta tctttttgcg taattccggc gtgaccttga tcggcctgcc aaggtgcttg
     3481 ccctctttct tcgctgaatc aatcccggcc cgctgacgtt ccagcatcga agtgcgttcc
     3541 atttctgcga tccccgccag catggtgagc atgagcttgc ccgctggggt tgttgcgtcg
     3601 aatccttccc ggaggctgat cagggtgatg cctttcgctt tcaggtcttc caccacttcc
     3661 agcgtgctga cggcattacg tcctatacgg tcgatagccg ccaccacgat cacgtcaccg
     3721 ctcccggcta ccttcatcag ggcggaaaat ccggggcgct ccattacggg cgtgatgccg
     3781 ctcactccct catcactcag gatccgcgca tcaggatagc gttgcaggat ggcgtctatt
     3841 tgcccgccaa ggttttgctc tgcggttgat acgcgtacat agccaaaaat cattatcgtt
     3901 accgtctaaa aaggtctctt taaaagataa tagacgcttt cgacgcataa aacaatctca
     3961 aatcctcgta agccccctct aattggggcg tcgcataagg gatgcctttt tgacactatg
     4021 cgagggcaac gcccgcgccc ctccccgttt gtcgtgacag tagtctgcat ctgcggcact
     4081 tcgccgctga ctttgacgag acaacacatg actaattcaa acgctgctca ggtggataac
     4141 cagctgagcc tgattgagga cgcgctgggc aaatacgccg cgccgctgcc tcaaatccag
     4201 tcccctgacc tcatccggga gcaggccgtc gatctgctca atcgcgccga tgtgctggaa
     4261 agcaacgcag acgagctgcg caccgagctg caaaaccgcg agcaggtcgt gcatgacatt
     4321 gatcgccagc tggcgacgct ggtcggtctg gtcgaggagg gtaaagcctg cctgcgttct
     4381 ggcgaaccgg ttcgccctga gtgcgccatg gctcactctc tgatccctga ggtggagaat
     4441 gagctgagtc tggcccgcaa tgccgccagc gccgccaacg ggcagctgct tgccgtcact
     4501 aaccagatcg acacgctgcg cagccagtat gcgcgaatga ttggacaggt agccttagac
     4561 gcccgcatgg ctcacgtaca ggcgctgctt gataccgcga tgcagcaggc tgctgagctg
     4621 gggctggagc tggcaaacaa tcatcagttt tccgctgcga tccgtgtaga taaccgcctg
     4681 gctattctgg gccgcaataa cggcatgtta tccagcctga gaaattatca agggagttcc
     4741 agataatgac tattaaagcc gtacttgcgc agctggctgc gttaaacagc acgatgacca
     4801 agagccacgc cggaaacgat accgggcgcg aggcaagact gaattttgaa gaccataaac
     4861 tgattggcga ctgctggcag gccaaagtct ccagtgctca gattgaggag ctgaaaaagt
     4921 ccctcaaagc tacccatgac ctacccgacg cagatcgtaa agcagcattc tcagccgttc
     4981 gccagtacct gctcaaatcc accgcaggcg atgcgctgga gcaggccatg agcggctccc
     5041 ctgtgcagtt cgcgccggat atgaccgtga aacgcaacat gagcaccgag caaatccacc
     5101 tcgcacggca gcagcagatc agcgatcagc agcttatccg tgattgtgaa gtcgccggag
     5161 tggccaccgg gcagatcgta gagctggcgg cacgcctcga agatactcgc ggcctgccga
     5221 ataacatcag acagcccgga attgatgctg tgcgccagca gttaactcag gcacaaccga
     5281 gccccgcaga gcagggcatc gactggagcg ctcagggatg gaaataaaca gccgggccgt
     5341 gttgctggcc tgtctgtctg cgttgcgctt gcctgagggt gagcgcacct ccgatcacgt
     5401 catgcagctg gcgcacctgc gcaccgttct gcgtaacgag gggtattcct cccctgctat
     5461 tcatgacgac gcggctttac tcaaagaggc tgaggggctg gcaaaggccc gccgtgagtg
     5521 gctggctgac tccgctgata tgcgtcaacg ccatgccgaa ctccagcacc ttgttgcgtt
     5581 aaacctctta cctgaggatg aagcgaggca ggaacagggc gataactacc gggagcacca
     5641 gttacgcgat ccggttaagc aggagggaaa acctgaatat gattgagtcc aatctggtga
     5701 tcccctcgcg cgttatggcc ccccatgacg cgcagaaaaa gcgcaggatg cacgcaagga
     5761 tccgcgccgc agcccgtgaa aagatgcggc gggttatggc agcgccaacg tggcactggc
     5821 gctaccctac gccgccgaga gcataaaaaa gggcccaaat atgggccctt tgttttttgc
     5881 gtgccagcac gcccctaccg ctaccgactg gcaaagctgc gcggttgtgt gaaagagctt
     5941 tttaccggga cgctttgggt ttgtgtgcgc ccatcagggt attgcaggtt tacattgata
     6001 ttggcgtctg aaatatcaat ttttcctccg cgttgcccgg ctggcatggt ttcaggggcg
     6061 atcttgtagt tgttctgatt gttcagtgcc atgttaacgc cctcagtaac cactgattgc
     6121 gggatgctgg catttttcac gttctctttg cggaggatgg cccgcgtcac gttcagcagc
     6181 gtgttctggt cggttaagtc cagttgctga tctggcccgt accctgtcca ttcgcttgcc
     6241 tgccggatgt agcgcggcac ctcaggatcg ccactggcat atgtgctgac aatctcgcgc
     6301 agggtgcgct tgcgtccgcc tttgaatgcc ccagtgctgt agcgcagcag ttgccccgca
     6361 gacgctgcaa tgcctgcctg ctgggatggg aagcgccgcc agtttccgtt aacgtctttc
     6421 aaattgccaa cgtttccgcc agcccagttt cctgcggcac cgctgccagc ggcggcggcg
     6481 gatggtgaag aaatatagtt gctgtctagc gcagcctctc ccgctgtttg cgggccgtat
     6541 gcagccgcgt gcgcatttgc attgccctgc tctacaaagt tgagctgctg ctggcgcatg
     6601 agctgctgct ggcgtttcag tgccctgtat cggtcgcctt ctggccctgc ggtctgcata
     6661 ccgacgccct tatcctgcaa ggtgttcatt tcctgctgat aggcatcgag acgccagcca
     6721 tatttgcggc gggcctgctg ctgcgtatca aggcgcatcc ccttctcata atcgcggcgc
     6781 agactgtcct cactgcctcc ggtcattttg accagtgcca tgcgcatgac atcgagagca
     6841 ggcagggcgc ggcgggcgta gtcctcaaac tggttgttga gcttcgccac gttatcgcgg
     6901 atctcgctgc cttcggtctt cgcagggcca tgcacggtgg caacctgagt gagcacgtct
     6961 ttcagtttct ccgggtcagt acctttaagg gcatcggtaa ggcgctggcg ttcgccagca
     7021 tcaaggcccc cgcgtttgag gtattcattg cccatggact ccagcccttt gccgctctga
     7081 atctggccca aagcggcgta actggtggcg tttacgctgt tagggttaat tttcaggcgg
     7141 ctgaggcgac tggagacgcc gctcatgtct gcgctgctca tctggtcaat tgccagcgcg
     7201 tcattgatgc tgacgccaag gtggcgcgag agagctgcta cggaatcagg gccgtagcca
     7261 taggcccggt ggatgccctg ccgggtcata tcgagcaggg tctgatcgcc gtgatgattg
     7321 ccgccaaagc gctgaccgta aagagtatca gggcccagcg tgctgctaat ggtgccgaaa
     7381 gcgccgccag actggaggac ttcgagcgcc atcgggttat tgatgccgtt gcgcatagcc
     7441 atgcgggcca tgaatgcccg tgacggctca cccatcgcac caccgcgctg gaggttcgca
     7501 ttaacacggc tcagcaggtt ggtggagccc tgcaaatcca tgccggggat ccctgagctc
     7561 atcaggccag ccattgcacc cgcatagcct ggtacatttg gcgcggtcag gcttgcgcgt
     7621 gcctgctggg tggcaaagtc gctgattgcc tgcatagctt cgccagcctg cgcaaacgcg
     7681 cctgatttgc cgatagcctc ccccatgagc aggcccatgc ggcgcagctg ctgatcgttg
     7741 tttacgacac gggaagcgga gagctggccc atcgtgcccg cgacgctgtt tgggtcgagg
     7801 ccgtaggaac gggccagacc gccagaaacc agcatcccgg tgccaaggtt ctggcccggc
     7861 tggatgttgg ctgcgcggga ataggtggag gccagcgcga tggcgtcacc gttggtcatg
     7921 cccagattgt tggcggtgct catgacgccg cgctggaggc tggaaaagct gacaatgccc
     7981 cccatctggc ggtatagctt gtcgagcccg atcacgttgt cctgtgcctg cccgatcttg
     8041 tctgcgaccg cgccgataat ctttcctact ccgagcgcag caagtccgcc gaccaagccc
     8101 atgagcccgg cacctgctcc gccagacagc ccggcgttca ttgccccgct aatggtgccg
     8161 ccgaccgggc cagcgttgcg cagcatcgtg ctgaggtgat tctgccatgc cggaggctgg
     8221 ttattattct gcggcccgct ctgaggcgct ggagaaggat ttgagggggt aggtgctggc
     8281 agcttaggtt tcggcgctgg ctggtcgtta aactccacgc cgagaaactg gagcatggac
     8341 tgcatttttt tgatgcgtac tgcctgatcg gtgtacatct ttgaccaatc agccataagc
     8401 ggattggtcg ctccctgtcc tgtcttgctc atagtctgtt tgagctcagt ctggatggag
     8461 agcagcttct gcatttgctt gatgaaagca ttcagatcgt cttttgactt gacgttaatc
     8521 ggctcgaatt tctgcttgtt ggcctgccct acctgagagg caaggatgcg gatctggtcg
     8581 ttgaccattt gaatctgttg cttgaggtct gccgcgtcaa actgcgcgga gaccgggatt
     8641 ttaatcgcca tgttatagcc ctgttttgtc atcgtcaggg ccagtctggc gtcacgacat
     8701 ttgaggcgct cgcattacgt cagtgacgcc gcaagccgcg ccagctgtgg ataactttac
     8761 taaatcgcac ttgctcaggt ttatcatttt gattaatctg taaagcagaa acaggctagt
     8821 gatagtcgcg tttccagcac accgagccga atacggtgtt aaacgggggc gcattccctc
     8881 cagagcatat cggcatgatg cgaaaggcgc agaccagtgc ggactctccg gggcagaaat
     8941 gcccgcatca ccgcataagt ccttatggtt tgcacggcgt gccatagttc gccaccacac
     9001 aaagccccgg cagaccatcg ccgggcacct aaccaaccct gaggatccat gaaaccaata
     9061 tttaaaacag acattgccag cgcactgagg ataagcgttg cgcatctcaa tcgactgata
     9121 gcggcgggcg tcatacctcc agctgtcggg cgtattaagc atgggcggct tttttggtac
     9181 atgacgccgg aactaaaggc catcatccgc cagcagcgcc gccccgaaag acaacgttaa
     9241 gagagagccg aaatgactgg gaagaatgac tggctgttaa tacctaattt gctggatgaa
     9301 gcgctggccc gcacgcctgc accgtcctgc ggtggtggct ttgagatctg gaagcgggac
     9361 atcaccggga tcatgtgctg gctgcgctat ctgagccgcg acgctgaggc cgtgaatgtc
     9421 tgcacccgat ggagtgagga gcccggcatt acacccgccc agcgttcgaa taatgcctct
     9481 cttttttctt ccaccgcccg ctatgtgctc agcctgccac cggacacggc gaaagcctac
     9541 gccatcggcc tgctgtaccg tgcgcccggt ctggttgatg acattcaaac gggccgcttt
     9601 ggggccgaat atcagcccac tgccgagcag ctgcgccagc aggaagccca gcgcgaagcc
     9661 agacagcagg aatttgaggc ccgtcagcag gagcaggagc tggcaacgca gaagcaacgc
     9721 cagaaagcct atgcagatgc gatgcgcatt tatggcaaga gtaacgccga tcccgatgcc
     9781 gtccgcgcaa ccccgtactg gcgcgagaaa gagaaagccg caggctttcc cctccccgtt
     9841 cctgagggca tccgctgcgg ttctcctcgc atgttcctgc cagtcgtcgg cccggtttac
     9901 tggaataaca gcgtgatcgt gccgctgcat gtcatcagtg agtatttgca gctgggccat
     9961 gtgtccatcg aggtcgtttg cggtacagct aacccgccag cctcccgcac tggtgacaag
    10021 cgcggcctca aaggtggatt gcgtcagggc gctttcttcc cgattaacct ggacaaagcc
    10081 cgccataatt tgccgcttgt tatcgttgag gggctcatga ctgggatcgc cgtttcgctc
    10141 atgactggcg gcaaactccc gataatctgc gccatgtcct gcgagttttt cagcaacgtg
    10201 atcgacgagc tccagattgc ctacccggta tcaccttttt acatcatcgg tgatgtggga
    10261 gcagggcacc gcaaggccgc agacctcgcc actgagaaag gacgcgccga gatttacgcg
    10321 gtagaccttg agccatgcct gccggagcag gaaggggccg acgcattcga tatgctggcc
    10381 cgtcatgggg tcgataatgg catggtgctg ctgcgctcca tgttccgcac tgcccggctg
    10441 gcgcgtggtg atgctactgt ctccccgtca tcgtcagtca atccttagta ccacaaagcc
    10501 gctctgtgac aggggcggct ttttcatgcc ttgaggagcc gaaaatgagt gagcaaatgc
    10561 caagccctga aatgctggat agcttgattt ttaaccatgc cgcagacact gccagcctgc
    10621 tggtatcacg gggcgtctgc gagcttgatc gcctctttgg tgaggggtac gccgccgcta
    10681 atccggttgt gctcaatcag tgggtggcgg tcgccagcac catgcagctg gcccagttgc
    10741 aaatcaatgc cgccaacggg ctggcctgtc agatcgagcg actgggggcc atggctgacg
    10801 ctatcgaggc cagcgccgca gcggcctacg cagggagaat gcaatgagcg agcgagtgca
    10861 gcagttaatc actgccgagc tgtgcagcat gatccccaag gcgctggcgc agtggttccg
    10921 tgagggcggc aaatcggcgg ggcctgaggg ccctgtgatt gcgttcggca agcgcatcaa
    10981 gcgcggcgga gtgatgacca ttgtcgggcg ctccatccga gggcacctgt gggccacccc
    11041 agcctattac gccgacgcgg ctcgcatcat gcgcaaggat aagcggggca aagcctaccc
    11101 cagccactgc gagattgagc gcgagacgtt cacctgccag ctgctgcgcc agatcatgag
    11161 cctgacgcct gcggcttatc cggggctccc tgaggctgtc ccggagtggc agaccattag
    11221 cgaggcggag cagcgccaga tcgttgagac cattaacgcc tgtttacgtt gagaggtgcc
    11281 catgcagctg gatttattca gacagaaagg cggcatggga ctctctgagc gggaagccgt
    11341 cgaggtggcc cgcctacgct ggcacgcttt ccgccgtgcg ttcgtgggcc cgccctgccc
    11401 tgagttcatc cgaggggccc gccctgcttg tcgcgtcata cctgccgccc ctcctgtcgt
    11461 ctttatccct gagcctgaga ttgagccgga gctggaaaca ttgccggagc catcgctgga
    11521 gcctgagagc gaggaatacg acgattttga tataccggac gccattccgc tgaatacgtc
    11581 gcaaattctt gcctctgcac gctatcagat agaagcggag cgcctgcaaa gcatgggctg
    11641 ctatcgtcgc gccagcaatc gctaccagaa ggccctcaca ctggctcagc caggcaaacg
    11701 agccgacaaa ctgcgagcga tggttaacag gtgcgcacgg ctggcgggta agtgtgttcg
    11761 ggaataacgc cgcgcatttc atcgcattac gtcatgcagg acgctgtatt acacaaaaat
    11821 ggacgctatc ctgcaccgac actaacgccc cgccaatcgg ggcataacgc aaggatttgt
    11881 gatggcaaag acaattgaac ttgataaatg tacccgctgc ggcggtttaa ccgcttccgc
    11941 tggcttttgg gcggcgatcc ccggcgagca agttggaagc acctcgcagg aggtatatct
    12001 gcccattgtt gcgtgggctt cgttaggcgt ggagcatcgg gcagtaattt ccggcgagca
    12061 tggtctgctt tactacgccc ctatcggatg cgttaccctg aggtttgacg cgaatatgct
    12121 cgacgagcag gggaacgagt tatgcctgac tgcggcgggc gatattggcg gggccgtcta
    12181 ttacgtccct attgctcgcg cataaccacg ggggcccatt gcgggccctt ttcttttgcg
    12241 gcccccgcgc cgtccctccc cgtaagggct gggaaggttg acgaatacgt cagcaatagc
    12301 gtactattgt tgtactgcaa gagcattcgc agggggcatc aaccagtaat tggccctttg
    12361 cgctgggcag tcaggaggct ggtctcctgt cggtagctca acctgaataa tcaggttggt
    12421 atctgaaccc acgagctaaa gattggctgc ggctaccaag cattacgaag ggcgcttatt
    12481 gcgccctttt gcttttatag cctgcctaac aacgtgcctt gtgtccggtg tgtctcatac
    12541 gccgttacta cgctgtaaat ccatccgctt tgagcccagt cggcctcttt tggctccaga
    12601 atgacgatcc caagcgccga gcgtaaaacc tttggcctgt gcttccctcc cggatgatta
    12661 aactcacaat aaacgcctgc acccggctga atcacatcac acacaaaacg cgccacatca
    12721 ttcacggtat gataaccgag ccgcaccagt tccttttcat gctctgccca gatatgacgc
    12781 acgccaaagc cgctattagg gcctctatga ttccccacgc gcagaaatat atccccggca
    12841 ggtattacat cccctcttga aacaaactcc ggtaaagagc cgaaacatgg gagccctgct
    12901 gggtgggcta tatggctgtt aggtgagcca ttaatgccgt agttattctt agccattgag
    12961 cagtccacta tcccgcagct tgtgccgata gtcccgcagg cggctgcgtg tccactctcc
    13021 cccggtcgcg gttcgatacc cggcagcatt aagcgccccc acaatatcct ccagactggc
    13081 ccgctgttgc gtcagtgaca cgatcagcgc gtcggcctcg ctatccactg cctgaaagcg
    13141 tggatcgctt gtggtgcgtt gtggtgcgtt tggtggcgtt gtcgtgcgtt gcatttccga
    13201 cttgtcaggc accgtctgac gttgcggtgc agctgtcttg cgttgtggtg cgcctgcgat
    13261 ggtctccagt agctcgatca cccggtcgag cttgtcagcg gcggcaggtg caggcacaac
    13321 cccaaggtag gcccgcagcg ctgctgcggt gatgtccgtg cgggtgaggt gttcggcgct
    13381 ggctcgttcg tcgagcagct gcacaaggtc gtcaggtagt cggatgctca gctggggcat
    13441 tgcgttgtcc tccgtttgtc atttcctgtc atgttacgtc atacgcagcg taatgcaatg
    13501 gagtgcgtca gggggagggg cgcagctgtc gcagcgcatt aaaacaatcc accatgaggc
    13561 cccgccgtgt gggcaaaaaa gcgctttcat caagaagtta tccacaattg cgggcgtgat
    13621 gatggaggat catttagatt gatcgtttac cttctggacg ctattctttg ggggcatttg
    13681 atttgggagg ttttggaacg gcaacccaga ttacaggcga aaaaaaacca gccgggcagc
    13741 tggtttttaa tcgcctcagg cagcgtcaac tgtctggtgc attccggtcg atgtcttggg
    13801 aacgtctccg
//
