LOCUS       NZ_CP127020            27322 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Staphylococcus aureus strain CC239-MRSA-III(var.) isolate
            Trinidad&Tobago_2020-009_371M plasmid unnamed1.
ACCESSION   NZ_CP127020
VERSION     NZ_CP127020.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35540728
            Assembly: GCF_030252735.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27322)
  AUTHORS   Monecke,S., Akpaka,P.E., Smith,M.R., Unakal,C.G., Thoms
            Rodriguez,C.A., Ashraph,K., Muller,E., Braun,S.D., Diezel,C.,
            Reinicke,M. and Ehricht,R.
  TITLE     Clonal Complexes Distribution of Staphylococcus aureus Isolates from
            Clinical Samples from the Caribbean Islands
  JOURNAL   Antibiotics (Basel) 12 (6), 1050 (2023)
   PUBMED   37370368
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27322)
  AUTHORS   Diezel,C., Braun,S.D., Reinicke,M. and Monecke,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2023) Optisch-Molekulare Diagnostik und
            Systemtechnologien, Leibniz Institute of Photonic Technology (IPHT),
            Philosophenweg 7, Jena 07743, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.9.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 14:34:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,181
            CDSs (total)                      :: 3,101
            Genes (coding)                    :: 2,946
            CDSs (with protein)               :: 2,946
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 106 of 155
            Pseudo Genes (incomplete)         :: 50 of 155
            Pseudo Genes (internal stop)      :: 23 of 155
            Pseudo Genes (multiple problems)  :: 23 of 155
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP127020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27322
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="CC239-MRSA-III(var.)"
                     /isolate="Trinidad&Tobago_2020-009_371M"
                     /isolation_source="Medical/diagnostic sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Trinidad and Tobago"
                     /collection_date="2020-01-16"
     gene            complement(<1..477)
                     /locus_tag="QQO11_RS15740"
                     /old_locus_tag="QQO11_15745"
     CDS             complement(<1..477)
                     /locus_tag="QQO11_RS15740"
                     /old_locus_tag="QQO11_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017432088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048517715.1"
                     /translation="MKNLKSFFIKNTLVLTSTALLFSSFEPVVHAAENKEVVKTVENDN
                     VEFNELLEGQEYIWEVLSRDDEGFKMFLDEQRAFNPNFDNDVLLAKQEGALNSSVFANN
                     SMTLNSNKPTPRGPIGATLKAIKALSPSLRHGGTAISWIIKPLSRKHAVLVKKYS"
                     /name="hypothetical protein"
     gene            complement(1977..>2081)
                     /locus_tag="QQO11_RS15910"
                     /pseudo=""
     CDS             complement(1977..>2081)
                     /locus_tag="QQO11_RS15910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(2141..2815)
                     /locus_tag="QQO11_RS15745"
                     /old_locus_tag="QQO11_15750"
     CDS             complement(2141..2815)
                     /locus_tag="QQO11_RS15745"
                     /old_locus_tag="QQO11_15750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISSau6 family transposase"
                     /protein_id="WP_001105943.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITNQAPSTKVAMSKVIKDFKLTPNCHCNSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRFLQIYGFSPCRVISIML
                     AS"
                     /name="IS6-like element ISSau6 family transposase"
     gene            2852..3763
                     /locus_tag="QQO11_RS15750"
                     /old_locus_tag="QQO11_15755"
     CDS             2852..3763
                     /locus_tag="QQO11_RS15750"
                     /old_locus_tag="QQO11_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_078056064.1"
                     /translation="MSNFATEPNVSYADILEILKIKKAYNVKQCGNVLEFKPTDEGYLK
                     LHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLSTKNAIDGDTL
                     EQSLKHLTKAFDRLSRYKKVKQNLVGFMRSTEVTVNKNDGNYNQHMHVLLCVENAYFRK
                     KENYITQEEWVNLWQKALQVDYRPVVNIKAIKPNQKGDKDIESAIKETSKYSVKSSDFL
                     TDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGNLINTSDEDKITDE
                     EAKAHSITAIWNFEKQNYYLRH"
                     /name="protein rep"
     gene            <4645..4746
                     /locus_tag="QQO11_RS15755"
                     /old_locus_tag="QQO11_15760"
                     /pseudo=""
     CDS             <4645..4746
                     /locus_tag="QQO11_RS15755"
                     /old_locus_tag="QQO11_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(5112..5459)
                     /locus_tag="QQO11_RS15760"
                     /old_locus_tag="QQO11_15765"
     CDS             complement(5112..5459)
                     /locus_tag="QQO11_RS15760"
                     /old_locus_tag="QQO11_15765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119692.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDGI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(5478..6094)
                     /gene="cadD"
                     /locus_tag="QQO11_RS15765"
                     /old_locus_tag="QQO11_15770"
                     /pseudo=""
     CDS             complement(5478..6094)
                     /gene="cadD"
                     /locus_tag="QQO11_RS15765"
                     /old_locus_tag="QQO11_15770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            complement(6275..6397)
                     /locus_tag="QQO11_RS15770"
                     /old_locus_tag="QQO11_15775"
     CDS             complement(6275..6397)
                     /locus_tag="QQO11_RS15770"
                     /old_locus_tag="QQO11_15775"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466482.1"
                     /translation="MFFYEDDDFDEMEEKYDYHEDKKIDDAFMPRKFIDVEKNP"
                     /name="hypothetical protein"
     gene            complement(6478..6666)
                     /locus_tag="QQO11_RS15775"
                     /old_locus_tag="QQO11_15780"
     CDS             complement(6478..6666)
                     /locus_tag="QQO11_RS15775"
                     /old_locus_tag="QQO11_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001030803.1"
                     /translation="MNKDTMLDKGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            complement(7246..7392)
                     /locus_tag="QQO11_RS15780"
                     /old_locus_tag="QQO11_15785"
     CDS             complement(7246..7392)
                     /locus_tag="QQO11_RS15780"
                     /old_locus_tag="QQO11_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001092935.1"
                     /translation="MNTKILTGMTGSSLERKINNFINDNQIEVIDIKFSSSVFYFGVMI
                     IYK"
                     /name="hypothetical protein"
     gene            complement(7397..7585)
                     /locus_tag="QQO11_RS15785"
                     /old_locus_tag="QQO11_15790"
     CDS             complement(7397..7585)
                     /locus_tag="QQO11_RS15785"
                     /old_locus_tag="QQO11_15790"
                     /inference="COORDINATES: protein motif:HMM:NF013603.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001559000.1"
                     /translation="MLSYGGLLKEKHKILNLDDAEDGNLINTSDEDKTTDEEEKAHSIT
                     AIWNFEKQNYYLKNLRS"
                     /name="hypothetical protein"
     gene            complement(7715..8659)
                     /locus_tag="QQO11_RS15790"
                     /old_locus_tag="QQO11_15795"
     CDS             complement(7715..8659)
                     /locus_tag="QQO11_RS15790"
                     /old_locus_tag="QQO11_15795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001132442.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDRNNNIYFIFSNKHLCEYLGYGEQKIIKLKKELVNFNLLTQERVGLN
                     KPNRLYLLKPNYDIEASLTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTELNNTN
                     YIENEDNDTYDMNDIISNTLINNNHHSNHTNHQKTEFNNDALKFQVLEELPQQLQDYLS
                     KFEIREIRIIKSVLLKGKKSFNTSHDTYYRLEDVEFEIVSVLKRFKAMLLQKNETVEAM
                     QGYLMQSIKAELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            9103..9873
                     /locus_tag="QQO11_RS15795"
                     /old_locus_tag="QQO11_15800"
     CDS             9103..9873
                     /locus_tag="QQO11_RS15795"
                     /old_locus_tag="QQO11_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000848988.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKNLNISFKKENGINYINDNDCLK
                     IIEKITKKERTMQNKESIKKERFNENTAEFEKHIYNNSNGFESLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEERQLN
                     YSFDTATNDRQSINPQEATFTEEYQNSNQQQKKIQPIEAELNHKGITKAKKDDSSNEDV
                     LKRDDKLSEEIESGPEDREVETPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(10189..10749)
                     /locus_tag="QQO11_RS15800"
                     /old_locus_tag="QQO11_15805"
     CDS             complement(10189..10749)
                     /locus_tag="QQO11_RS15800"
                     /old_locus_tag="QQO11_15805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(10954..12498)
                     /gene="qac"
                     /locus_tag="QQO11_RS15805"
                     /old_locus_tag="QQO11_15810"
     CDS             complement(10954..12498)
                     /gene="qac"
                     /locus_tag="QQO11_RS15805"
                     /old_locus_tag="QQO11_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_000622774.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSIMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            12676..13242
                     /gene="qacR"
                     /locus_tag="QQO11_RS15810"
                     /old_locus_tag="QQO11_15815"
     ARG             12677..13239
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13375..13560)
                     /locus_tag="QQO11_RS15815"
                     /old_locus_tag="QQO11_15820"
     CDS             complement(13375..13560)
                     /locus_tag="QQO11_RS15815"
                     /old_locus_tag="QQO11_15820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(13565..13903)
                     /locus_tag="QQO11_RS15820"
                     /old_locus_tag="QQO11_15825"
     CDS             complement(13565..13903)
                     /locus_tag="QQO11_RS15820"
                     /old_locus_tag="QQO11_15825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(14149..14757)
                     /locus_tag="QQO11_RS15825"
                     /old_locus_tag="QQO11_15830"
     CDS             complement(14149..14757)
                     /locus_tag="QQO11_RS15825"
                     /old_locus_tag="QQO11_15830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(14883..15461)
                     /locus_tag="QQO11_RS15830"
                     /old_locus_tag="QQO11_15835"
     CDS             complement(14883..15461)
                     /locus_tag="QQO11_RS15830"
                     /old_locus_tag="QQO11_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690625.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNRLNNQENKDK"
                     /name="recombinase family protein"
     gene            15833..16201
                     /gene="cadC"
                     /locus_tag="QQO11_RS15835"
                     /old_locus_tag="QQO11_15840"
     ARG             15834..16198
                     /name="cadC"
                     /gene="cadC"
                     /gene_name="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM/LEAD/ZINC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16194..18377
                     /gene="cadA"
                     /locus_tag="QQO11_RS15840"
                     /old_locus_tag="QQO11_15845"
     CDS             16194..18377
                     /gene="cadA"
                     /locus_tag="QQO11_RS15840"
                     /old_locus_tag="QQO11_15845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase CadA"
                     /protein_id="WP_000003264.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAKV
                     NFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFYKK
                     HSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDFDMK
                     TLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEALVMR
                     NGQEIMIHVDDIAVGDIMIVKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEV
                     FAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYTPIIMVI
                     AALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKG
                     GVYLEELGAIKAIAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALEYRSQHPLA
                     SAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKELNVSDFSLGF
                     ENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSKNVIQKLHQLGIKQTIMLTGDN
                     QGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVNDAPALAASTVGI
                     AMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVI
                     PGWLTLWIAILSDMGATILVALNSLRLMRVKDK"
                     /name="cadA"
     gene            complement(18612..19286)
                     /locus_tag="QQO11_RS15845"
                     /old_locus_tag="QQO11_15850"
     CDS             complement(18612..19286)
                     /locus_tag="QQO11_RS15845"
                     /old_locus_tag="QQO11_15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105968.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWHIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <19342..20085
                     /locus_tag="QQO11_RS15850"
                     /old_locus_tag="QQO11_15855"
                     /pseudo=""
     CDS             <19342..20085
                     /locus_tag="QQO11_RS15850"
                     /old_locus_tag="QQO11_15855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163428.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /name="FAD-dependent oxidoreductase"
     gene            20385..20792
                     /gene="merR"
                     /locus_tag="QQO11_RS15855"
                     /old_locus_tag="QQO11_15860"
     CDS             20385..20792
                     /gene="merR"
                     /locus_tag="QQO11_RS15855"
                     /old_locus_tag="QQO11_15860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator MerR"
                     /protein_id="WP_000525462.1"
                     /translation="MGMKISELAKACDVNKETVRYYERKGLIAGPPRNESGYRIYSEET
                     ADRVRFIKRMKELDFSLKEIHLLFGVVDQDGERCKDMYAFTVQKTKEIERKVQGLLRIQ
                     RLLEELKEKCPDEKAMYTCPIIETLMGGPDK"
                     /name="merR"
     gene            20809..21294
                     /locus_tag="QQO11_RS15860"
                     /old_locus_tag="QQO11_15865"
     CDS             20809..21294
                     /locus_tag="QQO11_RS15860"
                     /old_locus_tag="QQO11_15865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746200.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_000746202.1"
                     /translation="MKKRISFTAIMTVLLIGLTACGAESDTANESKVQDIQGNPVSLPN
                     EKPTLIYFMATWCPSCIYNEEIFKEMHQLNPNDVQLITVSLDPNTDTKESLAKFKQDYG
                     GDWPHVLKNGKEIADTYGVKQLEEIVLVNSENEVFYRSVRPSFDDLKEALTQIGVEL"
                     /name="TlpA disulfide reductase family protein"
     gene            21291..21971
                     /locus_tag="QQO11_RS15865"
                     /old_locus_tag="QQO11_15870"
     CDS             21291..21971
                     /locus_tag="QQO11_RS15865"
                     /old_locus_tag="QQO11_15870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010351.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="WP_000010352.1"
                     /translation="MSFSFLFILTAGMVAAFNPCGIALLPSYISYLIGGETKDHSFRYA
                     IFKGLGLGGAMTTGFLTIFVLAGLLIGGLGSALTGIFPILSLVMGILIALLGLGMLFGK
                     HLPIKIGSFQVKPGKWSIYFYGIAYAVTSLGCTLPAFMLVVSASLNDNSVTAVIIKFII
                     YSLGMGIVVTAITMVSLISRQLVQKFLHNYMGSIQKIAAVVIFLSVLYMAYYWYFGSGG
                     ICTF"
                     /name="cytochrome c biogenesis protein CcdA"
     gene            22059..22445
                     /gene="merT"
                     /locus_tag="QQO11_RS15870"
                     /old_locus_tag="QQO11_15875"
     ARG             22060..22442
                     /name="merT"
                     /gene="merT"
                     /gene_name="mercuric transport protein MerT"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22503..24146
                     /gene="merA"
                     /locus_tag="QQO11_RS15875"
                     /old_locus_tag="QQO11_15880"
     ARG             22504..24143
                     /name="merA"
                     /gene="merA"
                     /gene_name="mercury(II) reductase"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            24228..24878
                     /gene="merB"
                     /locus_tag="QQO11_RS15880"
                     /old_locus_tag="QQO11_15885"
     ARG             24229..24875
                     /name="merB"
                     /gene="merB"
                     /gene_name="organomercurial lyase MerB"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(25073..25588)
                     /locus_tag="QQO11_RS15885"
                     /old_locus_tag="QQO11_15890"
     CDS             complement(25073..25588)
                     /locus_tag="QQO11_RS15885"
                     /old_locus_tag="QQO11_15890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000377078.1"
                     /translation="MDSHLNHILSYWQGPPLEGAKTIISKYGYPQEATMSRLIWYNSGP
                     WKRTIVYKDPVPHNFPTPHLDFLKQTIDYKVPVHLYDAIAAFDGSVYLDRTTGEASAKC
                     HEEAMNFLSLNLLNDIVTGKRDVQGAKAFYAQTAEQFTKYHITSPYTEGFLFPMQYNTA
                     DLGVTYFK"
                     /name="hypothetical protein"
     gene            complement(25707..26381)
                     /locus_tag="QQO11_RS15890"
                     /old_locus_tag="QQO11_15895"
     CDS             complement(25707..26381)
                     /locus_tag="QQO11_RS15890"
                     /old_locus_tag="QQO11_15895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105988.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYTLYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(26618..26713)
                     /locus_tag="QQO11_RS15895"
                     /old_locus_tag="QQO11_15900"
     CDS             complement(26618..26713)
                     /locus_tag="QQO11_RS15895"
                     /old_locus_tag="QQO11_15900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000889979.1"
                     /translation="MLEILVHITTTVISGCIVALFTHWLRNRNDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     ARG             complement(10958..12498)
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.81"
                     /coverage="100.0"
     Typing          3819..3966
                     /name="MOBV"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2876..3763
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.625"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(7408..7585)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.179"
                     /coverage="95.0"
                     /evalue="3.73e-65"
     Typing          complement(7716..8659)
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.577"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tgaatatttt tttactagaa cagcatgttt tctacttaat ggtttaatga tccaagatat
       61 agcagttcca ccatgtctca aagaaggtga tagagcctta atagctttta aagttgcacc
      121 gataggacct ctaggagtag gcttatttga gtttaaagtc atagaattat tagcaaatac
      181 tgaagaattt aaagcacctt cttgttttgc tagtaaaaca tcattatcaa aattaggatt
      241 aaaagctctt tgctcatcta gaaacatttt aaatccttca tcatctctag ataaaacttc
      301 ccaaatatat tcttgtcctt ctaacaattc attgaattct acattatcat tttctactgt
      361 tttaacaact tccttatttt ctgcagcatg aactacaggt tcaaaactag aaaataataa
      421 tgcagtagat gttagtacca aagtattttt aataaaaaaa ctttttaaat tcttcatatg
      481 acttttatcc tccaattata aatgttaaaa ttttttatta ttaaatatta tatacataaa
      541 aggaattaaa ttattatgaa aaaagtaaac aaagagtact tattgaactt tataattgta
      601 acgttcttac tcggaataat aatcatacct atatccgtat tagtattctc aataccattt
      661 tttagcataa taggtttcca atcattagca gataatttaa atataagttc tttaataaca
      721 ataaattggt attcaaataa tatgttttat aacattggct atattgcatt attctttata
      781 gtaacttatc taatatttat ttttcttgaa ctttttataa tatttttaca tataaaatac
      841 aaaaagaaat ttaataatat tatcttattc atattcttta taactgctaa tatgatcgta
      901 ttaaacttaa taattttgaa gattttctac aacattcata taaacttata ttttcaaatt
      961 ttcatttatt ctttatgctt ctatctttta tttactcata aagagattta caaaatattt
     1021 gaagaaaata aaagtaaaaa ataaaaaaat aaaaaaatta atctctcaaa aagttttctc
     1081 ggcataaaag tacctctaac ttttatacat aaagtcatga gcataaggga aagtgccacc
     1141 acttttatat tttggcatac ccataacgtg gtgaactcgg cagtgccgag ttatttttcc
     1201 tagaaaaaaa gtgacatcac ttttttaact catatgtata aaaaccataa cgttatgtat
     1261 acatacaggt tacgtataca tatactttat gtgtataaaa catacacaaa agacatgcat
     1321 catacacatc aattttttta aaaatacatg tctttttgat atatattttt ttttgcgttt
     1381 taagaggtca tttagagcat tctctaattt tgagtacaaa aatacgtaat ataaaaaaat
     1441 cgtcctttta aaaccttttt aggacatttt aaacacattt ttatgatttg gatcaatgta
     1501 gaataaatgt cataaacgta tagaaaaaat acgtcgtcat ttctaagtac agataaattt
     1561 ctgatgcagt actaaattat ggggaaacct acctgtaaaa aataaaaaga ttactatatt
     1621 ttaattttat tttttctgtt cgttttttcg acaccaggac gggcgatttt tacgtactgc
     1681 ccatttacat gcaaatttaa aaattagcaa taaatcgttc cgaatttgca ttttaaatgg
     1741 gcaaacgtgc cgtttgatca catagttcgt gtagcgacaa aaagagtata acgaaagtat
     1801 aataagcgta taaaaaaagt gtaatgatag aaaatagcat tatacttttt tagtcgttca
     1861 tcgctcatca gaacaacaaa taaattttta agaaataaat tttgagagtt gaccacccac
     1921 gttctccgta aactacaaat gtgggtggtc aactctcaaa atatttttat atttttttat
     1981 tgttcttctt cggtaagttc gtgaagttca cttgccaggt actctttctg attccaaata
     2041 taataaattt ggtaaaggta ttcagttgga tcgatttctt ggttctgttg caaagttaaa
     2101 aaataagtgt ctaaccttat gtttaaaata atacttcgta ttaactagct agcatgatgc
     2161 taattacacg gcatggcgaa aacccgtaga tctgaagaaa tctgcggttc tttttatata
     2221 gtccataaat acattcaatg cctttgatcg tattctttgc cgtattgata ctttgataac
     2281 ttattttcct tactttgata tgacgatgat cttgttcaat gagattattt aaatatttag
     2341 agttacaatg acagttgggg gtaagtttaa aatctttaat cactttggac attgccacct
     2401 tcgttgaagg ggcttggttt gtaattatca tttgaggttt gccaaattgt ttaataagac
     2461 gtttaataaa cgtatatgct gagtgattat ctcgtttctt acgtaacgaa atatctagtg
     2521 tatggccatc tgcatcaata gcgcgatata aataattcca ttgcccttta attttgatat
     2581 acgtctcatc tatatgccat ttataataag cttgcttatt ttttttcttc caaatttgat
     2641 acaaaatagg agcatattcc tgtacccatc gataaattgt tgaatgatga acatagatgc
     2701 ctcgttctct caatatttca gatatatcac gataacttaa tgcatatctt agatagtagc
     2761 caacggctac agtaatgaca tctttgtcaa attgcttata tctgaaataa ttcatcctct
     2821 gcacctcatt ttttgttgac tattatacta tatttctaac tttgcaacag aacctaatgt
     2881 aagctatgca gatatacttg aaattttaaa aataaaaaag gcttataacg taaaacaatg
     2941 tggtaacgtc ttagaattca agccgaccga tgaaggttat ttgaaattac ataagacgtg
     3001 gttttgtaaa tcaaagctat gtccagtttg taattggagg cgtgctatga aaaatagtta
     3061 tcaagctcaa aaagtgattg aagaagtaat taaggaaaag ccaaaagcac gttggttgtt
     3121 tttaacactt tcaacaaaaa atgcgataga tggagatact ttagaacaaa gtttgaagca
     3181 tctaactaaa gcatttgata ggttgagtag atataaaaag gttaaacaaa atcttgttgg
     3241 atttatgcgt tcaacagaag ttaccgttaa taaaaatgac ggtaattata atcagcatat
     3301 gcacgttttg ttatgtgttg aaaatgcata ttttagaaaa aaagagaatt atataactca
     3361 agaagaatgg gttaatttat ggcaaaaagc attacaagtt gattatcgac ctgttgtaaa
     3421 tattaaagca attaaaccta atcaaaaagg cgataaagat attgaatcgg caatcaaaga
     3481 gacatcaaaa tattcggtta agtcatctga ttttttaact gacgatgacg aaaaaaatca
     3541 agaaattgta agtgatttag aaaaaggttt atatcgaaaa cgtatgttaa gttatggtgg
     3601 attgcttaaa caaaagcata aaattttaaa cttagacgat gccgaagatg gtaatttaat
     3661 taatacaagt gatgaagata aaataacaga tgaagaagca aaagcacatt caattacggc
     3721 aatttggaat tttgaaaagc aaaattatta tttaagacat tagtgatgac tgatgtcttt
     3781 tttattgatt ttttgtaaaa aagtactgtc ttatttttgt gacaaatgct gtatgtagtg
     3841 tcacaaaagt gtgacactac agctttttat gatatcactt taaaattact taaaaccctt
     3901 ggaatgtctg gctttgccag acctattatt tttgaatgat agcaaattct ccttatgctc
     3961 ttacggagtt cttagagaaa aattgaaatt tcttgatttt tgataaaaac gccctgcagg
     4021 aatttagaaa aacatgggga agttttaaaa gattttatgc tcatttttaa tttgcattta
     4081 aatgggcagt gttaaaaaat tagtcactgg ttttgctgaa atttttgttt gtgaaattac
     4141 catatattta tttgactcat atttgcgttt taagagcttg tatagatttt taagtagaag
     4201 actataagat ttacctctaa atctttaaaa taccctctta aaattcaaaa taaaggtgtt
     4261 tataatttga ataagtcctg agataaagtt ttttaaaagg agtggttttt tgaagaggtc
     4321 tttatttatt ttacaaatta ttcttggtat ttttttattg ttttttattt ataagcaaat
     4381 gaatcaaaat catttagata cttggtttat tctttataca gtctttttta tatttttttc
     4441 atcgtggttt gataaacatt ataaaaaaag ttagacgacg catttatgcc gagaaaattt
     4501 attgatgttg agaagaaccc ttaactaaac ttgaagacga atgtcggcat agcgtgagct
     4561 attaagccga ccattcgaca agttttggga ttgttaaggg ttccgaggct caacgacaat
     4621 aaagcaattg gaataaaata cacaggcatt gaatgtattt atggactata taaaaagaac
     4681 cgcagatctc ttcagatcta cgggttttcg ccatgccgtg taattagcat catgctagct
     4741 agttaataca aagtattact ttaaacataa ggttagacac ttatttttta actttgcaac
     4801 agaaccttac attatctatt ttcttttctc tccatgggcg ttgttttcca cttttcgtca
     4861 tatcttttaa cgttttatta tcttgatttt cggttatact tctagtagta ttatattgca
     4921 tataaaaaga actccagtat tgatttagat tagacacctt aatcatatta ctggagtttt
     4981 tttatgtcaa attttatttt ccccaagcaa aacagtatga aacgccgtca tatcaacgct
     5041 tcaaaaggat tttagaaaag aacgttattt ctatatagta tcaagacaag aagaaactcg
     5101 tttcactcgt ttcaaaaacc ctcatgattt ttagagaaaa actctcttat tccatcgtct
     5161 ttaataaaat aatatgccat ctttccatct ttataaaaat caagtacctc atttttatat
     5221 aaaagcctta aatgatgtga agttgaagca acactcattt tcaatatcaa agaaatatca
     5281 caaacacaca actcatcttc tttaatcaaa gataatatga ttttcaattt cttctcatca
     5341 caaatttttt ctaaaatgtt aagtaatttc ttagatttat catcttctaa aaaacttaaa
     5401 gcattgttaa ctttatcctc atgtacacag atcacatcac aagtattttc ataactcata
     5461 taaaatcaca ccctaaatta aaatataaat cctaaaattg tttgaatagt gtcattttca
     5521 ataataataa ataaacctaa agctatataa ataatagcca taatccaacg actaaatttc
     5581 tcaacaattt ctccaattcc tgggatatta gctaattttt gtgcagtaaa caccaagaag
     5641 aaaattaaaa ttaaaaagac aaacagagta agtaataaat tagtaacact taatgtcaca
     5701 aaatacggaa caaataaacc aatattatcg gcgccacaac ttgctatcgt aacaattgca
     5761 accgtaccaa ctaatttaga caatcctttt tcattcagtt cttttttagc tctcttttct
     5821 ccttcacaat cacataaata gccactttaa ttccaagata aattggtatt aaacccaata
     5881 aacctaatat ccacttctct gaaacataat ttaatacaaa agctaaaaac aaactaacta
     5941 atattaaaat aatagaccct aaatattgac caatataaat atctctatat tcttttttag
     6001 tctttgctct agcaaaaaat attaataaaa ttactaataa atcaaatgct gtagcaatat
     6061 aaagaatagc agcagtgaca accgtttgaa tcatacatac acctcattca aaaatatttt
     6121 tgaatgtatt ataactaata tttttaaata atcataggtg ctttattcca attgctttat
     6181 tgacgttgag cctcggaacc cctaacaatc ccaaaacttg tcgaatggtc ggcttaatag
     6241 ctcacgctat gccgacattc gtcttcaagt ttagttaagg gttcttctca acatcaataa
     6301 attttctcgg cataaatgcg tcgtctattt ttttatcttc atgataatca tatttttctt
     6361 ccatctcgtc aaaatcatca tcttcataga aaaacaaaaa gtaagcaaca acaccaatag
     6421 gaataaaaaa tagtgtgaaa acaagaagaa actcgtttca aaatcccctc aaatattcta
     6481 attattcttt ttgaaattca taactttaac aaccaaataa atagcattta ttcccatcaa
     6541 aataacatac ggaattaata tatataaatt ttccaaatga gatataaaaa ttaatccaag
     6601 taaaaagaaa acatttaaaa tagttgctat aacgtaacct ttatctaaca ttgtgtcttt
     6661 attcaaaata aaaactcctt tttaaaaaac tttatcacaa gacttactca aattataaat
     6721 acctttattt tgaattttaa gggggtattt taaagattta ggggtaaatc atatagtttt
     6781 ctatctaaaa cctacataat ctcttaaaac gcaaatatga accaaataca tatatgctat
     6841 tttcaaaaac aaaattttaa ataaaaccaa tgactatttt tttaaacact gcccatttac
     6901 atgcaaatta aaagttagca taaaatcctt taaaacttcc cccatgtttt tctaaattcc
     6961 tgcaagacat tttttatcaa aatcgagaat ttttattttt tctctaagaa ctccgtaact
     7021 ccgtaagagc ataagggaaa tttgacccca tgtatacatg gggtatctgg caaagccaga
     7081 caattcaaag cttcaacaat atttttatgt ggggtcataa aaagcttaag tgtcacactt
     7141 ttgtgacaca atatattgca tttgtcacaa aaataagcca gtactttttt ataaaaaaac
     7201 agtaaaaaaa gacatcagtc atcactaatg tcttaaactc tttaattatt tataaataat
     7261 cattacccca aaataaaata cagaacttga aaacttaata tcaatgactt cgatttggtt
     7321 atcattaata aaattattga tttttcgttc taaagaactt ccagtcattc cagttaaaat
     7381 tttagtgttc atatttttaa ctccttaaat tttttaaata ataattttgc ttttcgaaat
     7441 tccaaattgc tgtaatcgaa tgtgcttttt cttcttcgtc tgtcgtttta tcttcatcac
     7501 ttgtattaat caaattacca tcttcggcat cgtctaagtt taaaatttta tgcttttctt
     7561 taagtaatcc accataactt aacatacgtt ttcgatacaa accttttcta gatcacttaa
     7621 aatttcttga tttttttcgt cgtcatcagt taaaaagtca gatgatttaa cggaatattt
     7681 tgatgtctct ttgattgtta taaaatcatt tgaattattg attaaagata ttatattgtt
     7741 tcatgttttt acggcgcata taaagggcat gtgtttcttc aagttcagct ttaatggatt
     7801 gcattaaata accttgcata gcttcaacgg tttcattctt ttgtagcaac atcgctttaa
     7861 aacgtttcaa tacacttaca atttcaaact caacatcttc taaacgataa taagtatcat
     7921 gtgaagtatt aaatgacttt ttccctttga gtaatacgct tttaataatc cgaatttctc
     7981 taatttcaaa tttacttaaa tagtcttgaa gttgttgtgg caattcttcg agtacttgga
     8041 acttaagggc gtcattatta aattcagttt tttgatgatt tgtatgattc gaatgatgat
     8101 tattatttat taaagtatta gatataatat cattcatatc atacgtatca ttatcctcat
     8161 tttctatata attagtatta tttaactcag tatcattaga ctgtgaattt ggaagttctt
     8221 gaccacttaa attcacagtt ctagaacttc caaattcatt gttctggaac tgtgaatttg
     8281 gaagttcctt ggtaagactt gcttcaatat cataatttgg ttttaataaa tataatctat
     8341 ttggtttatt aaggccaaca cgctcttgag ttaataaatt aaaatttact aactcttttt
     8401 tcaattttat gattttttgt tctccataac ctaagtactc gcacaaatgt ttattactga
     8461 aaataaagta aatgttatta tttctatcta cccattcatt ttggatggat aattcgaaac
     8521 gatcttttaa taatgcatac ataattttgg cttctgctga cattttctta aaatatgcat
     8581 cttcgaacaa atatttagga agttggtaaa atctttcagt ttttacttgt gataaattgt
     8641 atttctcaaa attgggcata ataaaaacct catttccact ttttggatag aggtaataaa
     8701 acaattttta cgtaggttat atgttttgta cttgcactta tatgattaga tatatataat
     8761 acaagtatca aaaaattata taaacagacg aatgcgaatc gttttattac cgagagtcga
     8821 tgctacgcca atagtatcga ctcttttaat attcacaaag taatattaac acttttaaga
     8881 ttgtatataa agctttttaa gtttagttga aagaacattg taactttaaa atgataaaaa
     8941 ttcaccactt tagtacctaa ttagtcacct atagaaggtt ttaacggcta attaggtact
     9001 aaagtagtga aataggtagt aaatttagat gtcgaaagat gaaaaaatat ttgttaggtg
     9061 gtaaaattta ggtaccaatt tatgtaccta aggatgaatg ttatgaaaac tattaaaatg
     9121 gttgctgatg aattgaatgt aactaaacaa actattgtta ataatgctaa aaacttaaat
     9181 atatctttta aaaaagaaaa tggaattaat tatattaatg ataatgattg tttaaaaatt
     9241 atagaaaaga tcactaagaa agaaaggaca atgcaaaata aagaatcaat aaaaaaagaa
     9301 agatttaatg aaaatactgc agagtttgaa aagcatatat acaataattc aaatggtttt
     9361 gagtcattaa aaacaaaagt aaatgaatta gaaaagcaaa tagaaatctt tgaaactaga
     9421 gctaaaaatg acgaaaaata tattgagaat ttaactaaac aactagatca acaaaatagc
     9481 aatgttaata cattaaataa actgttggag aatcaacaaa tattagcttt agaaagtaat
     9541 aaaaagattc aaaaactaga aaaccaatta gaagaagaaa gacagcttaa ttactctttt
     9601 gatacagcga ctaatgatag acaaagcatt aatccgcaag aagcaacttt tactgaagaa
     9661 tatcaaaata gcaaccaaca acaaaagaaa atacaaccaa tagaagcaga attaaatcat
     9721 aagggcataa ctaaagcgaa aaaggatgac agttcaaacg aagacgtatt aaagagagat
     9781 gataaactat ctgaagaaat agagagtgga cctgaggaca gggaagtaga aacacctaaa
     9841 aaggggtttt ggagtcgttt gtttggtagc taaaataatt aattaggcac taaaagttta
     9901 taacttttag tgccttttat atagtgagaa cttctggtaa tcatcagtta tgttaaactc
     9961 taacaaaaac taaattatca gaagaattat ctagggtatt aaacataggt aaatcaattt
    10021 tctatcgcca atagtataaa catcatccat attaatctga agatagctac ataattcttt
    10081 aacagcatag cctttatttg tataaggcgc cataaactct attaaatatg gtttgttttg
    10141 aggtttctat gtttaatcat ttaatttttc attatataaa tcgaataatt ataaaaagtc
    10201 atcatacttt ttatttttta aaaatatttg aaaatttaat agtaatccaa ttataagatc
    10261 aaatatcatt atcattataa tcaaggcaac tataatcact gtgacactcg ttacataaca
    10321 agctagtaat ctccagataa aattgacatt ttcaccaatt ccataactta acatattaca
    10381 aagtagtaaa agaataataa tacctatact gtaaattaaa attgtcagtg tatatttttt
    10441 aataactcta ttaggaaaca atagttcatc tattaggttc tttttcacca gtatctctcg
    10501 ttcaattcta tctttgtcac agattttgat tttactattt tttatttttt cctctaataa
    10561 aataacctcg aacgatctgc taatttttaa taaatatgca ggaaaagcta atgttaagca
    10621 taatgtaatt aattcattta cattgttcat gtaacttata aaatagatga aagttgctac
    10681 tagtgctcct aaaaatatag ttatattaag ttctacatca aatattttaa aaatatctgc
    10741 tctattcatc agttaatcat cctttcaagg tttattaata ctaataaatt attagatata
    10801 ggtatatcat attattaatt taagaaattg tcttttataa ttttacttaa taataaaaaa
    10861 gtagaaccat ttaaaattaa tggttctact ttttaactat tactaatttt aaaaataaac
    10921 taatctacaa tatctaaaaa tatatgttta gtactatttt tgtttagtta tatcaagtga
    10981 tttgggaatt aacaaataga caactattga aatgataatc atgataatcc cacctactaa
    11041 agcagttgct acaaaagcat cattaaatga tgttacagcc tcgtttgcaa gctgttttat
    11101 ccccgtagct ttagctactt cgacagcgcc cactacagat tcttcagcta catgagctaa
    11161 atctccaact ataccttttg atgaaaaaga tgaaatatct aaaaatacac gataaagcat
    11221 agaagatagg ctaccaagta ctgctacacc aaaaacattt ccaaggtcat acatagactc
    11281 ttcaacagca gctgcattac ctgcttttga tgtaggtgtt tctaacatta ttagagcaga
    11341 tgcaactgct agtgaagcca taccagctcc aactaaaatt aatgctaaag ccattataga
    11401 atatgataat ggatgaccaa agaaatacat aataaacatg ccaatggctg caattccaat
    11461 tccggaaggt aacactattt tcggtccaaa tcgcgccgct aatccgggtg caattggtgc
    11521 aaacaccata tctcctattg ccataggtaa taggtataag ccagctttaa aaggagaaag
    11581 ttcttccaca acctgtaacc attgtgaagc taataacaaa acagatgcca ttgcaaacat
    11641 tgtcataaat gcagcaattg taccagctga aaatgatctc tttttaaaaa gtcttacgtc
    11701 taacattgga tcagaacttg ataaattacg tttaacaaat atcactatca tggtaattgc
    11761 taatactatt acaacccatg gaataatatc tgctagtcct tcttttgaaa attctttgat
    11821 actccatacc agtccaatca tgcctgcaat tgataaaatt gtagaaggaa tatcccacga
    11881 gtgagacttt tcttttgata acttagactc tggtaataaa aataaacctg ctacaactgc
    11941 tattatcgca aacggtacat taattaaaaa tgccgagtgc catgaaaatt gctcaagtaa
    12001 agctcctccg ataattggtc caaaaacagc acctatcgat gaagcgattg accatacagc
    12061 taatgcagtg gccctttctt tagggttttc aaaaattact cttatcattg aaagagtagt
    12121 tggcattatt aaagcacctg caataccaag taaaaatcga atagctatta cgaactctgc
    12181 actttctgcg aaaaatatag ctaatgaaac gaggccaaat aaagcaaatc cagttaataa
    12241 tgcttttttt cttccccatt tatcagcaaa ggcactcaat ggaattataa agccagctaa
    12301 aacaagagag tatatatcaa ctatccataa ctgttgggta ccagaaggct ctaactctct
    12361 tactaattcc ggtaaagcca taattaatat tgtcatatcc attgtaacaa caaacaaact
    12421 aacagctaat actactagtg cagtccatct tttttttgat gtcatcatat cagtagtttt
    12481 tgtaaaaaat gaaatcattt aagttccctc caatccttat agaccgtgcg atcggtctat
    12541 aaggattata atctattttt ttacatatta caacaaaaaa tcttgcgaaa tttaaatggc
    12601 tgtattgtgt tatacaatta ttctttgaat tttttgtgct atcattgata gtacttaata
    12661 ctcattaaag gcgtgatgaa cttgaaagat aaaatactag gtgtcgcaaa ggaattattt
    12721 ataaaaaatg gatataatgc cactactact ggagaaattg ttaaattatc agaaagtagt
    12781 aaagggaatc tttattatca ctttaaaaca aaagaaaatc tatttttaga aattttaaat
    12841 atagaagaat ctaaatggca agaacagtgg aaaaaggaac aaatcaaatg taaaactaat
    12901 agagaaaaat tttatttata taatgaacta tctttaacaa ccgaatacta ttatccactt
    12961 caaaacgcaa taattgaatt ttacactgaa tattataaaa ctaatagcat taatgaaaaa
    13021 atgaataaat tagaaaacaa atatatagat gcttatcatg taatttttaa ggagggtaat
    13081 ttaaatggcg aatggtgtat taatgatgtt aatgctgtta gtaaaatagc agcaaacgct
    13141 gttaatggaa ttgttacctt tacacatgaa caaaatatta atgaaagaat taaacttatg
    13201 aacaagttct ctcaaatttt tttaaatgga cttagtaaat aattatatat atattcttga
    13261 aataccaata aatattattt ctaaattacg ttcgttattg agacaaaatt taatagtact
    13321 actacacaaa aagagagtgc gaattcgcac tctctttttg tgataaatga atggttaaga
    13381 aaataattca tccacagttg tatcaaacaa tcttgccaac ttaaatgcta atgtcaatgt
    13441 aggatcatat ttattgtttt ctattgcatt aatagtttgc ctagacactt ttaattcttt
    13501 acttaaagtt tcttgagaaa ttcctttttg ttttctatat tctctaattc tatttttcat
    13561 taatttaacc tttagatgta tattttttat ttgtagtata gtaattaaac agcataagaa
    13621 atagtgctac aattataaag aaaatttctg gatattgaga aaaccaagat ccttcaatac
    13681 ttggtgacaa acctgtaaat ttaagcacta gtgtaaataa catacaatat acaatccaaa
    13741 taaaactttt agccagtatt tcaataaaca ttttacgttg tctttcatcg tatcgatctt
    13801 gttgtccttt tttatctaat gtttctgaag gtaaatattt gttagttata gccgtccata
    13861 aacaagaaaa aattaaaata ataataaaag gaattaaatt cattataaca cctcataaat
    13921 gtaaaaagta tttgacattt atgagtgtaa atatttttga tacaaatgtc aaatactttt
    13981 tacattataa tatattttaa aacaccttat tagtaaaaca attactatat agaaagctgc
    14041 gaactcgtac tcttttttct tgtataatta ttaaaatctc aattcaataa tatgttatgg
    14101 aatttgagac actgtgagag acgctcattt gcattgacaa tcaatttatc aagataatcc
    14161 cttatcatgt ttaattctat aaactgtttg tcttgtgata ttaacttctt tcgcaatctt
    14221 actaatcgct ttgccttctt ctaacatttc caccacgcga tgataaataa cacgtttctg
    14281 tgggtcttta gcatttggtg aataaagtaa agggcgccct ttatatacgc ctttttcctt
    14341 cgcaacttga atcccttgcg cttgtcgacg tttactttca tttctctctt gttctgaaac
    14401 cattgctaat atttgaatga ttaaatcttt cataaactta tccagtaatg gattgccaat
    14461 tacttcattc atcataggta agctggtaat cattaactga acgtcttttt cttttaaata
    14521 attcacagtt tcaataattt catcatagtt acgtcctaaa cgatcaatag attccacaac
    14581 gaatcgatct cccattctga caaaattgag tgcttcttga aatacaggtc tattttccac
    14641 tgactttccc gactgtttct ctgtaaagat tttctccaca ccaaacgtct ttaaattatc
    14701 caattgtctt tctaaatttt gatctatcga tgatactctc gcataaccta taatcattca
    14761 tcttcactcc ataataaata tacaccctaa tcatacgttt taattgttat aatttcaaca
    14821 attctttttg tatggttagg gtgtgtcctg tctattttta tctttcttaa aacttagtaa
    14881 tattatttat ctttattttc ttgattattt aacctattga gataacgata gattgtggta
    14941 cgtgaaactt tccattgttc tgcaatagtt ttaattggtg ttccattatc ataaagtgtt
    15001 ttgagtaact ttaaatcttg tttatttaat ttttcgggac gacctccata gcgtcctcta
    15061 gcacgagcgg caattcgtcc tgctgaagaa cgttctaaaa ttaagttgcg ttcaaactct
    15121 gcaaatgctg cgaataaatg aaataacaat tgtcctgtag aacttgattt atccattgtt
    15181 atattttctt ctaaactatg aaaactcacg cctcgattat taagttcatt aactaatgtg
    15241 attaaatctt ccatattacg ccctagtcta tctagtctcc aaacaacaat cgtatctcct
    15301 gccctcgcaa attcaatggc tttatctaaa ccaggacgtt tactttttga tccacttatg
    15361 tggtcgctaa atatcttttc acaaccatat tgatttaatt gatcttcctg caaatttaaa
    15421 ttttgtaaac cagttgaaac tcttgcataa cctattttca aaatacaaac ctcctatata
    15481 catcttcatt gtatcataac ttaattctaa ccatatttat gaacatagat tttctgttgg
    15541 gttattgaac actaaaatat gtatactcgc tatatatata gacataaaaa gagagtgtat
    15601 agaaaatggt tattttctgt acacagtttt aaatatcaaa aacattattt acattttacg
    15661 tttaagaact aatggttaaa aatttcattt tgtcaaaaac gttcgttttt gagactagaa
    15721 ttttatgccc tacttacttc ttttattttc attcaaatat ttgcttgcat gatgagtcga
    15781 aaatggttat aatacactca aataaatatt tgaatgaaga tgggatgata atatgaaaaa
    15841 gaaagatact tgtgaaattt tttgttatga cgaagaaaag gttaatcgaa tacaagggga
    15901 tttacaaaca gttgatattt ctggtgttag ccaaatttta aaggctattg ccgatgaaaa
    15961 tagagcaaaa attacttacg ctctgtgtca ggatgaagag ttgtgtgttt gtgatatagc
    16021 aaatatctta ggtgttacga tagcaaatgc atctcatcat ttacgtacgc tttataagca
    16081 aggggtggtc aactttagaa aagaaggaaa actagcttta tattctttag gtgatgagca
    16141 tatcaggcag ataatgatga tcgccctagc acataagaaa gaagtgaagg tcaatgtctg
    16201 aacaaaaggt taaactaatg gaagaagaaa tgaacgtcta tcgggtccaa ggatttacat
    16261 gtgcaaattg tgcaggaaag tttgagaaaa atgttaaaaa gattccaggc gttcaggacg
    16321 caaaagtaaa ctttggcgct tctaaaattg atgtatatgg aaatgcatcg gttgaagaac
    16381 ttgaaaaagc aggtgctttt gagaatctaa aagtatctcc tgaaaaacta gcgaatcaaa
    16441 cgatacaaag ggttaaagat gacactaagg ctcataaaga agagaaaaca ccattttata
    16501 aaaaacatag tacattgctg tttgccacac tactaattgc ttttggttac ctttctcact
    16561 ttgtaaatgg agaagataac ctcgtaactt ccatgttatt tgtaggttcg attgtaattg
    16621 gcggatattc actatttaaa gttggttttc aaaatttgat acgctttgat ttcgacatga
    16681 aaaccctgat gaccgtagca gttattggag ctgccatcat tggtgaatgg gcagaggcat
    16741 ccattgttgt cgttctcttt gcaatcagtg aagcacttga acgtttttct atggatagag
    16801 caagacagtc cattcgttca ttgatggata ttgccccaaa agaagcactt gttatgcgga
    16861 atggtcagga aataatgatc catgtggacg atattgccgt gggtgatatt atgatcgtca
    16921 aaccagggga gaaaattgcc atggatggga tcattataaa tggtgtgtcg gctgtcaacc
    16981 aggctgctat aacaggagaa tctgtccctg ttgccaaaac ggtagatgat gaagtatttg
    17041 caggtacgct taacgaagag ggactacttg aagtaaaaat caccaaatac gtagaggata
    17101 caactatctc caagattatt catctggttg aggaagcaca aggggagcgc gctccagcgc
    17161 aagcattcgt agataaattt gcgaaatatt atacgccgat cattatggtt attgcggcgc
    17221 tcgttgcagt cgttccacct ttattctttg gtggaagttg ggatacttgg gtttatcaag
    17281 gattagcggt acttgtagtt ggatgtccgt gtgcattagt tatttctact ccaatctcga
    17341 ttgtctcggc aattggaaat gcagctaaaa aaggtgtgtt gattaaaggc ggtgtctatc
    17401 tagaagaatt aggagccatt aaggcaatcg catttgataa aacaggaaca ctgacaaaag
    17461 gtgtaccagt ggtaacagat tttgaagtat taaatgacca agtggaagaa aaagagctat
    17521 tctctatcat tacagcttta gaatatcgtt cacaacatcc acttgcttca gcaataatga
    17581 aaaaggcaga gcaagataat atcccttatt ctaatgtaca agtggaagaa ttcacttcga
    17641 ttactgggcg aggtataaaa gggattgtaa acggaactac ttactatatt ggaagcccaa
    17701 aacttttcaa ggaattaaat gtttccgatt ttagccttgg gtttgaaaac aatgtgaaaa
    17761 tcctacaaaa ccaaggaaaa acagccatga ttattggaac ggaaaaaaca attctcggcg
    17821 taattgccgt tgcagatgag gttcgtgaaa caagtaaaaa tgtgattcaa aaacttcatc
    17881 agttaggtat caagcaaaca attatgctga caggtgataa tcaaggtact gcaaatgcaa
    17941 tcggtacaca tgtaggcgtt tctgatattc agtctgaatt gatgccacag gataaattag
    18001 attatattaa aaaaatgcaa tcggagtatg ataatgtagc tatgattggc gatggcgtta
    18061 atgatgctcc agcacttgct gcatctactg ttggaattgc aatgggcggt gctggaacgg
    18121 atactgcaat tgaaacagct gatattgcat taatgggaga tgatttaagt aagcttccat
    18181 ttgcagtaag actcagtcga aaaactttaa atatcattaa agctaacatc acttttgcta
    18241 tcggaattaa aataattgcc ttactattag ttatcccggg atggttaacc ctttggatag
    18301 cgattctttc cgatatggga gctactattt tggtagcatt aaatagttta cgactgatga
    18361 gagtgaagga taaataggta gaaaacagaa tagtaaggtc acgctgtgcg caattcaagg
    18421 ggggcttttc aatttgaaga aaagtcctac ccctaaaata taaaatattg gagatggaaa
    18481 aatgatcgca acgatactta cagcagctgc ggtatatgta gcaacaggaa ttgatatctc
    18541 gttatattaa ttctggttct gttgcaaagt aaaaatatag ctaaccacta atttatcatg
    18601 tcagtgttcg cttaacttgc tagcatgatg ctaatttcgt ggcatggcga aaatccgtag
    18661 atctgaagag acctgcggtt ctttttatat agagtgtaaa tacattcaat accttttaaa
    18721 gtattctttg ctgtattgat actttgatac cttgtctttc ttactttaat atgacggtga
    18781 tcttgctcaa tgaggttatt cagatatttc gatgtacaat gacagtcagg tttaagttta
    18841 aaagctttaa ttactttagc cattgctacc ttcgttgaag gtgcctgatc tgtaattacc
    18901 ttttgaggtt taccaaattg tttaatgaga cgtttgataa acgcatatgc tgaatgatta
    18961 tctcgttgct tacgcaacca aatatctaat gtatgtccct ctgcatcaat ggcacgatat
    19021 aaatagctcc attttccttt tattttgatg tacgtctcat caatatgcca tttgtaataa
    19081 gcttttttat gctttttctt ccaaatttga tacaaaattg gggcatattc ttgaacccaa
    19141 cggtagaccg ttgaatgatg aacgtttaca ccacgttccc ttaatatttc agatatatca
    19201 cgataactca atgcatatct tagatagtag ccaacggcta cagtgataac atccttgtta
    19261 aattgtttat atctgaaata gttcatacag aagattcctt tttgttaaaa ttatactata
    19321 aattcaactt tgcaacagaa ccagaatttt gatatagatc ttgtagatat ccttttagaa
    19381 aagtcgaaag agattggcat acaggtacat cttcaacatt ccgttgaatc cattgaaaaa
    19441 gaacaaggaa agtttcatgt gtacgctcga aaaaaagagg atataacgcg gtttgaagca
    19501 gacattgtta ttcatggtgc tggacggggc cctgccttag atatgaatct tgaaaaaggg
    19561 aatatagaaa ggaaaaaaca tggtgtccat gttaatgagt atttgcaaag tgtaagtaac
    19621 ccgaatgtct atgcagctgg agatgctgca gcaacggatg gcttgcccct cacacctgta
    19681 gccagtgcag attctcatgt cgtagcatct aatttattga aagggaacag caaaaaaatt
    19741 gaatatcccg tgattccatc tgctgtattt accgtaccta aaatggcatc ggtaggtatg
    19801 agcgaggagg aagccaaaaa ctctggccgg aatattaaag taaagcagaa aaacatctcc
    19861 gactggttta cgtataaacg gacaaatgag gactttgctg cgtttaaagt gctgattgac
    19921 gaagatcatg atcaaattgt tggtgctcat ttgattagta atgaagccga tgaactgatt
    19981 aatcattttg caacagccat tcgttttggg atttcaacca aagaattgaa acaaatgata
    20041 tttgcctatc caacggcagc ttcggacatt gcacacatgt tgtaagtttg cgttttgtga
    20101 gatgtttata aaccacttta tcgtctaatc ttgttatatg atcttagaat caaaaagaaa
    20161 ataacttttt tgacagccgc atttttcaac ggaagaatgt ggcttcttgg cgtgaagagc
    20221 agatatcttt attcttaaac ttctaaaaaa gcttatgtga acacttgata aataaggttt
    20281 tttatctgac ctattttata agattattct ataaaagaaa aaataatgta tgacttgacc
    20341 gtgtactatg gtacagggtt tatacttttt attgaggtga caatatgggg atgaaaatca
    20401 gtgaattggc taaagcgtgt gatgtgaata aagaaaccgt tcggtattac gagcggaaag
    20461 gattgatagc cgggcctccc agaaacgaat cagggtatcg aatatattca gaggaaacag
    20521 cagatcgggt acggtttatt aaacgaatga aggaattgga tttctcgcta aaggaaatcc
    20581 acctgttgtt tggtgtggtt gatcaagatg gggagagatg taaagatatg tacgccttta
    20641 ccgttcaaaa aaccaaagaa atcgagcgga aagtgcaggg tttgttacga atccaacggt
    20701 tattagagga attaaaagaa aagtgtccag atgaaaaggc gatgtatacc tgtcctatta
    20761 ttgaaacgtt aatgggaggg cctgataaat aaatggggga agatttgaat gaaaaaacgc
    20821 atttccttca ccgctataat gacggtgttg ttaatcggtt taacagcttg tggagcagaa
    20881 tctgataccg cgaatgaatc aaaggttcaa gacattcaag gaaatccagt cagcctacct
    20941 aatgagaaac ccacactcat ttattttatg gcaacctggt gtccatcttg tatatacaat
    21001 gaggaaatct ttaaggaaat gcatcaacta aacccgaacg atgttcaatt gatcacagtt
    21061 agtttagacc ctaacacaga tacaaaagaa agccttgcga aatttaaaca ggattatggc
    21121 ggggattggc cccatgtttt aaagaatggt aaagaaattg cggataccta tggcgtcaaa
    21181 caattggaag agatcgtact ggtcaattct gaaaatgagg tattctatcg ttctgttcga
    21241 ccgtcctttg atgatttaaa agaagcgttg actcaaatag gagtggaatt atgagttttt
    21301 cgtttctctt cattctgacc gctggaatgg ttgcggcctt taatccttgt ggtatcgcct
    21361 tgcttccttc ttatatctcc tatttaattg gaggcgaaac aaaggatcat tcgttccgct
    21421 atgcaatttt taaaggatta gggcttggtg gagcgatgac cacggggttt ttaacgattt
    21481 ttgtattggc tggtttattg ataggaggat tgggaagcgc actaacaggg atttttccga
    21541 ttctttcatt ggttatgggt atactcattg ctttattggg gttgggcatg ctattcggga
    21601 agcatttgcc gattaaaata ggatcttttc aagtcaagcc agggaaatgg tctatctatt
    21661 tttacggaat agcctatgcc gtgacatcac ttggttgtac cttgccagcc tttatgttgg
    21721 tggtctctgc atcgctgaat gacaatagcg taacggccgt gatcatcaag ttcatcatct
    21781 actcccttgg tatgggaatt gtggtgacag cgatcacgat ggtctcattg atttcacgac
    21841 aattggtaca gaagtttctg cacaactata tgggttctat ccaaaaaata gcagctgttg
    21901 tgattttcct ctccgttttg tacatggctt attactggta tttcggttct ggtggcattt
    21961 gtacatttta aaatccaacc gatcaggtgt aacaaaaaat agatgaaaga tgtaaaaaag
    22021 ctaaacgaac aaatttcaag ttaggctata ggccatgtat gtaccttaac caaagaataa
    22081 aatttttttt agaaagagtg gtgagaatga tggatgagaa tcgctcgaaa ggtaaccgct
    22141 ggggtgtttg ggcctttttc ggaatattat tggttccttt attggttcct ttactttgtt
    22201 gcgcaggacc gattctcctt gttgcattag ggagcacagg tattggtgcc ctctttgctg
    22261 gtgcgacagg aaattggtgg ttgaccggca tttttgcagc attggccatt gttatgattg
    22321 ctctgatcct cagcaagttg ttgaagaaca aatacaattc tcctgaaggc aatggaaaaa
    22381 caaaaaataa aacggattgc tgtacgcctc cagagagcgt ggatcggaaa catgagacaa
    22441 gataaatatg agataaatgt acagaactgt ctatcaaact ttaaatagaa agagggattc
    22501 aaatgactca aaattcatat aaaataccca ttcaaggcat gacatgcaca ggctgtgaag
    22561 aacatgtaac cgaagcattg gaacaagccg gagctaaaga tgtttcggcc gatttccgac
    22621 gcggtgaggc catttttgaa ctcagcgatg atcagatcga aaaggctaag caaaatattt
    22681 cggcagccgg ctatcaaccc ggagaggaag aaagccagcc ctctgaaaac agtgtagatt
    22741 tcaatcggga tggcgattac gatcttctga ttattggttc cggcggtgcg gcgttttctg
    22801 cagctatcaa ggccaatgaa aacggggcga aagtggccat ggtagaacgg ggaaccgtcg
    22861 gggggacctg cgttaacatc ggttgtgtac cgtcaaaaac catgcttcgt gccggtgaaa
    22921 taaacggtct cgcccaaaac aatccgttta ccggacttca aacgagtacc ggtgctgcgg
    22981 accttgccca attgaccgaa caaaaagatg gattagtcag tcaaatgcgt caagaaaaat
    23041 atatagactt gatcgaagaa tatggatttg atctcattcg tggcgaggcc tcgtttatcg
    23101 acgataagac gatacaagtg aatggacaaa acatcacgtc taaaagcttt ttaatcgcaa
    23161 cgggggcttc tccggctgtt ccggaaatcc cgggaatgaa tgaggttgat tatttaacaa
    23221 gtacatccgc actcgaatta aaagaggttc cacaacgatt ggcagtgatc ggttctggct
    23281 atatcgcagc ggaattaggt caaatgtttc acaacctcgg aacagaagtg actctcatgc
    23341 aaagaagcga gcgtctgttt aaaacctacg atcctgaaat ttccgaagcc atcgatgaat
    23401 ccttaactga gcaaggactt aacctgatca ctggggtcac ttatcaaaag gttgagcaaa
    23461 acggtaagtc gacaagcatt tatattgaag tgaacggtca agaacaagtc atcgaagccg
    23521 atcaagtcct cgtggcaaca ggaagaaagc cgaacacaga gactttaaac cttgaatcag
    23581 caggtgtgaa aacagggaaa aaaggcgaag tgctgaccaa tgaatatttg caaacgtcga
    23641 ataaccgaat atatgccgcg ggcgatgtga ccctcggtcc gcaattcgtt tatgttgcag
    23701 cttatgaagg cgggattgtg gcaaataatg cgttgggtct agcgaaacgc aaaatcgatc
    23761 ttcgctttgt tcccggcgta accttcacca atccatcgat cgccacagtc ggcttgactg
    23821 aacaacaggc aaaagaaaaa ggttacgatg tcaaaacatc ggtccttccg ttggacgctg
    23881 taccgcgggc cttagtcaat cacgaaacaa caggggtcta taaacttgta gtcaacgccc
    23941 aaacccagaa attgatcgga gcgcacattg tgagtgaaaa tgctggagat gtgatttatg
    24001 cggcaacgtt agcggttcaa tttggattga ccattgaaga ccttacggat agctttgcgc
    24061 cttatttaac gatggctgaa ggattaaagc ttgcagcctt gacgtttgat aaagacgtat
    24121 cgaaattatc ttgttgtgca ggctaatggt tccttttgat tctaatgcta tgttgcagga
    24181 ggcacttaaa acaatgaagt ggagaaaata taaggaggaa taagcttatg aaaaatattt
    24241 cagaattctc agcccaactt gatcaaactt ttgatcaagg ggaagccgtc tctatggagt
    24301 ggttattccg tccgttgcta aaaatgctgg cggagggcga tccagtcccc gttgaggaca
    24361 tcgcggcgga gaccgggaag cccgtcgagg aagttaagca agtcctacag actctaccta
    24421 gtgtggaact tgatgagcag ggccgtgtcg tcggttatgg cctcacactg ttccctaccc
    24481 cccatcgctt cgaggttgat gggaagcaac tatatgcatg gtgcgccctt gacacactta
    24541 tgttcccagc actcatcggc cggacggtcc acatcgcttc gccttgtcac ggcaccggta
    24601 agtccgtccg gttgacggtg gaaccggacc gcgttgtaag cgtcgagcct tcaacagccg
    24661 ttgtctcgat tgttacacca gatgaaatgg cctcggttcg gtcggccttc tgtaacgacg
    24721 ttcacttttt cagttcaccg agtgcagccc aagactggct taaccaacac cctgagtcga
    24781 gcgttttgcc cgttgaagat gcctttgaac tgggtcgcca tttgggagcg cgttatgagg
    24841 agtcaggacc tactaatggg tcctgttgta acatttaatc ttaggcaatt acgcctgcgt
    24901 caatcttggc cttacgatga tgtcctgtaa ccgaagctct atctagtgaa accaatttta
    24961 tgggaaacca aataaataaa aagatcaatt gcttgtgcct atatcgggga gttaataaag
    25021 cgagaaagtg gattcttgaa tataggagta aataaggtgc caaaatggca ccttatttaa
    25081 aatatgtaac gccaaggtct gccgtattat attgcattgg aaaaagaaaa ccttctgtat
    25141 aaggagatgt tatatgatat ttggtaaact gttcggcagt ttgggcgtag aaagcttttg
    25201 ctccttgaac atcacgtttg ccagttacaa tgtcatttaa caagtttaaa gataaaaaat
    25261 tcatcgcttc ctcatgacac tttgctgatg cctcacctgt agttcgatct aagtagacac
    25321 ttccatcaaa agcggcaatc gcatcatata agtgtacggg cactttataa tcgatggtct
    25381 gcttaaggaa atcaaggtga ggggtaggga agttatgagg gactggatcc ttatatacta
    25441 tcgtgcgttt ccatggcccg ctattgtacc aaattaatcg actcattgtt gcttcctggg
    25501 gatatccata cttactaatt atggtttttg ccccttccaa cggtggtccc tgccaatagg
    25561 acaaaatgtg atttaaatga ctatccattg ccatacctcc taaacatttg cctaaaagca
    25621 ttgtatgccc aataaatgaa ttttaggggt tctgttgcaa agtaaaaaaa tatagctaac
    25681 cactaattta tcatgtcagt gttcgcttaa cttgctagca tgatgctaat ttcgtggcat
    25741 ggcgaaaatc cgtagatctg aagagacctg cggttctttt tatatagagt gtaaatacat
    25801 tcaatacctt ttaaagtatt ctttgctgta ttgatacttt gataccttgt ctttcttact
    25861 ttaatatgac ggtgatcttg ctcaatgagg ttattcagat atttcgatgt acaatgacag
    25921 tcaggtttaa gtttaaaagc tttaattact ttagccattg ctaccttcgt tgaaggtgcc
    25981 tgatctgtaa ttaccttttg aggtttacca aattgtttaa tgagacgttt gataaacgca
    26041 tatgctgaat gattatctcg ttgcttacgc aaccaaatat ctaatgtatg tccctctgca
    26101 tcaatggcac gatataaata gctccatttt ccttttattt tgatgtacgt ctcatcaata
    26161 cgccatttgt aataagcttt tttatgcttt ttcttccaaa tttgatacaa aattggggca
    26221 tattcttgaa cccaacggta gaccgttgaa tgatgaacgt ttacaccacg ttcccttaat
    26281 atttcagata tatcacgata actcaatgca tatcttagat agtagccaac ggctacagtg
    26341 ataacatcct tgttaaattg tttatatctg aaatagttca tacagaagac tcctttttgt
    26401 taaaattata ctataaattc aactttgcaa cagaatcttt tatagtatca aagaaaatta
    26461 ataattctaa ttatagagtt acacttacgt ttcttatgtt tttgcattcc tctactaacc
    26521 agtgttataa tatgattaac aagaattcta gcgtgaatac accaatcccc tcactattgc
    26581 cgtagtgagg ggatttttta ggtgtgacta tagtcgccta tttatcgttg cgattgcgta
    26641 gccaatgcgt aaataacgca acaatacaac cactgatgac tgtggtcgtg atgtgaacaa
    26701 gaatttctag catgaataac acctcctctc tgcgtctaaa tttgacgcct gagagatagg
    26761 cgactctatt attataccat ctgtgaatat acaagcatat ctacttccga taagtcgtct
    26821 tatgttatat aacttcgttt tttatagtat caagacaaaa gaagaaacgc agttcaaaat
    26881 catcacctaa attcattaat ctaaagaaaa aacggtgtaa taaatagtga atattatagt
    26941 ctattaaaga atagatttaa aaacactcta aaaggtgcat taaagatttg taaaacttta
    27001 atatatcctt tttaggtgaa aacttatgat aattgtaggt tctctcatta tctatgatta
    27061 ttaattttaa ctgtatctag aaaatcatca ccccaatcac aaattgaaaa tactacttta
    27121 tcaagataag aaaaaagaaa aaaacttgcc ctaagatttt ataaaatctt agggcaagtc
    27181 agctcaatat ctaaataact aaaaatacaa tataagttaa agttttcgca tcacttcttg
    27241 gtatacctgc tttaacaaaa gcattttcaa cagctgattt cgtagactta tctaacctat
    27301 caattgcatt agacatcttt ct
//
