LOCUS       NZ_CP126857             5523 bp    DNA     circular CON 21-APR-2024
DEFINITION  Enterobacter hormaechei strain Ehh_7 plasmid pEh7_6, complete
            sequence.
ACCESSION   NZ_CP126857
VERSION     NZ_CP126857.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35394390
            Assembly: GCF_032202685.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 5523)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss
            companion animal clinic and their genetic relationship to clinical
            human isolates
  JOURNAL   J Antimicrob Chemother 78 (12), 2950-2960 (2023)
   PUBMED   37923369
REFERENCE   2  (bases 1 to 5523)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2023) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_032202685.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 14:01:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,106
            CDSs (total)                      :: 4,993
            Genes (coding)                    :: 4,900
            CDSs (with protein)               :: 4,900
            Genes (RNA)                       :: 113
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 93
            CDSs (without protein)            :: 93
            Pseudo Genes (ambiguous residues) :: 0 of 93
            Pseudo Genes (frameshifted)       :: 25 of 93
            Pseudo Genes (incomplete)         :: 69 of 93
            Pseudo Genes (internal stop)      :: 13 of 93
            Pseudo Genes (multiple problems)  :: 13 of 93
            Pseudo Genes (short protein)      :: 1 of 93
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP126857.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5523
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Ehh_7"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="pEh7_6"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-12-07"
     gene            complement(170..493)
                     /locus_tag="QPR83_RS25440"
                     /old_locus_tag="QPR83_25425"
     CDS             complement(170..493)
                     /locus_tag="QPR83_RS25440"
                     /old_locus_tag="QPR83_25425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_172971213.1"
                     /translation="MLTMWVTDDEHRRLLERCDGKQLAAWMRQTCLDEKPARAGKLPSI
                     SPALLRQLAGMGNNLNQIARRVNAGGGTGHDRVQIVAALMAIDAGLERLRHAVLDKGRD
                     DDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            1142..1273
                     /locus_tag="QPR83_RS25445"
     CDS             1142..1273
                     /locus_tag="QPR83_RS25445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_059686908.1"
                     /translation="MHEPPVQSDCCACSGNYHLESNPERHDKTPLAAATGKGCTRYY"
                     /name="hypothetical protein"
     gene            1638..2696
                     /locus_tag="QPR83_RS25450"
                     /old_locus_tag="QPR83_25430"
     CDS             1638..2696
                     /locus_tag="QPR83_RS25450"
                     /old_locus_tag="QPR83_25430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012508929.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_071949222.1"
                     /translation="MAIYAVWNNKGGVGKSYLTFQLASEYARQNPTKKVLVIDLCPQAN
                     SSSMLLGGMVNGENTLNQIHSATQRKTISGYIEDRIRSPYIPTNTGSNYVINVSTYNSR
                     IPNNLYLVTGDEQLELQASRVVGASFPGPHDAWRTVHLWINDLISDICNSWDNDDSCVF
                     IDCNPSFSIYTELALTAAERLLIPFSADGSSKRAVKAVLSLVYGERRHQNEPQSDFYLN
                     SNRYSMSLPQIYMYVGNRLTQMNNSSASAFKTVVTEIGDEIWKVWQTKPSLFCIHPNGN
                     STPNNKKSFRNMFQYEVNDANTASVVSGALGIPIATLTAGNKNVSGRTIKVNQTQLDKQ
                     VPNIVALAGMIE"
                     /name="ParA family protein"
     gene            complement(2725..2982)
                     /locus_tag="QPR83_RS25455"
                     /old_locus_tag="QPR83_25435"
     CDS             complement(2725..2982)
                     /locus_tag="QPR83_RS25455"
                     /old_locus_tag="QPR83_25435"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_057060549.1"
                     /translation="MGFNNDQNKDLQDKQADLLDQTYTLGWMDGYSEGYDDAIDDSQNA
                     LNKLENENELLNEIIEKKDNIINEMASGVGKALQTVKKNK"
                     /name="hypothetical protein"
     gene            complement(2972..3157)
                     /locus_tag="QPR83_RS25460"
                     /old_locus_tag="QPR83_25440"
     CDS             complement(2972..3157)
                     /locus_tag="QPR83_RS25460"
                     /old_locus_tag="QPR83_25440"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_109553065.1"
                     /translation="MTEDNVKNISDYRKKNDAVDANGSAVSSKNAPARLSEKLRNAIPS
                     GLRTQMRQQMRNKHGL"
                     /name="hypothetical protein"
     gene            3556..4107
                     /locus_tag="QPR83_RS25465"
                     /old_locus_tag="QPR83_25445"
     CDS             3556..4107
                     /locus_tag="QPR83_RS25465"
                     /old_locus_tag="QPR83_25445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_058999046.1"
                     /translation="MKDMKAVVVFTGKDLNIMRTEGGSGYWHARTDRLNDAEYLIAVRN
                     RRETWAVKDLEHGTAFLIAKITGCFKNPDYDDRNVITFDEYAEIHSPDAWKMLTGGQRY
                     PVAYLNAQEAFLRIGVTPEQLEWKKFHPSSPSLPNAVVPSLAEEKTEKLSLNEAIERAK
                     KDISNATGIDSSAITISIKI"
                     /name="hypothetical protein"
     gene            complement(4311..4526)
                     /locus_tag="QPR83_RS25470"
                     /old_locus_tag="QPR83_25450"
     CDS             complement(4311..4526)
                     /locus_tag="QPR83_RS25470"
                     /old_locus_tag="QPR83_25450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137421.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWENAFAEWRTMSGLMQRENA
                     ALSERVTGLSRQVQSLSEQLRRLSQG"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(4530..5015)
                     /locus_tag="QPR83_RS25475"
                     /old_locus_tag="QPR83_25455"
     CDS             complement(4530..5015)
                     /locus_tag="QPR83_RS25475"
                     /old_locus_tag="QPR83_25455"
                     /inference="COORDINATES: protein motif:HMM:NF016710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_057060552.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESE
                     KRISAAILDHDRKLSSAMSQRTKGMLRMVSQTWLTIVLVSVLLIASSAGILWWQGQQIL
                     DNYTTIREQKSTQAILSERNSGVQLSTCGEQGRRCVRVNPEAGRFGEDSSWMILAGK"
                     /name="MbeB family mobilization protein"
     gene            5266..5511
                     /locus_tag="QPR83_RS25480"
     CDS             5266..5511
                     /locus_tag="QPR83_RS25480"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_058999050.1"
                     /translation="MQSQPAVNDGLPGIDARTVGAVVIRLETPAGQQLRIWDQEVQLQP
                     PLVLVLNPQHAVLVFIKSGHQNPLEARHQLFTLAGR"
                     /name="hypothetical protein"
     Typing          complement(608..780)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="93.103"
                     /coverage="100.0"
                     /evalue="9.410000000000001e-66"
     Typing          705..1310
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.388"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(174..493)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.458"
                     /coverage="100.0"
                     /evalue="1.46e-61"
     Typing          complement(4208..5523)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.027"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaaggacagg acgccggagg tgtatttttt ggcgtagggc gaggcgtcga taagctcccg
       61 gacttcctcc ggttttccct gaagcacact ggcgccctcg cgctgccggt cttttcccag
      121 aaggtaatcc accggcccgg aaccacctcc gcgtccccgg ggatgaaatt taacgatcat
      181 catcccgccc cttatccagc acagcatgac gcaggcgctc cagtccggca tcgatggcca
      241 tcagcgccgc cacaatctgc accctgtcat ggccggtacc gcccccggca ttaacccggc
      301 gggctatctg gttcaggtta ttacccatgc cggcgagctg ccgcagcagc gccggcgaga
      361 tcgagggaag tttgccggcg cgggcgggct tctcgtccag gcacgtctgc cgcatccagg
      421 ccgcaagctg tttaccgtcg cagcgttcca gcagacggcg gtgctcatcg tcggtcaccc
      481 acatcgtgag cattttgctg cgtttgtctg ccaatccggc ctcctgataa cgccgcgacg
      541 ggcgggaaat ctgttcccgg tcggcgcggt gttggacaag ccgcaggcgc gtcagtggtt
      601 ttagcgggtt tcggggcgca gccctgaacc agtcacgcag cgctagcgga gtgtatactg
      661 gcttaatatg ttggcacagg tgcggaagtc agtgaagtgc ttcatgtggc aggagagaaa
      721 tgcagcagcg cagcgtaagc ataatatgtg atacaggata tattccgctt cctcgctcac
      781 tgactcgctg cgctcggtcg ttcggctgcg gcgagcggta ccggcttaca ggcggggcgg
      841 aaatttccta ggagatgcca ggaagaaact taacggggaa gcgataaggc cacggcggag
      901 ccgtttttcc ataggctccg cccccctgac aagcatcacg aaatctgacg ctcaaatcag
      961 tggtggcgaa acccgacagg actataaaga taccaggcgt ttccccctga tggctccctc
     1021 gtgcgctctc ctgttcctgc ctttcggttt accggtgtca ttccgctgtt atggccgcgg
     1081 ttctctcatt ccacgccaga cactcagttc cgggaaggca gttcgctcca agctggactg
     1141 tatgcacgaa ccccccgttc agtccgactg ctgcgcctgt tccggtaact atcatcttga
     1201 gtccaatccg gaaagacacg acaaaacgcc actggcagca gccactggta agggatgtac
     1261 aagatattac taacgcagag ttcttgaagt tgaagcctaa ctacagctaa actgaaagga
     1321 cagatttggt ggcagcggtc ttgtacaccc tgttaccacg gttcagaagt tccccaactt
     1381 actgatcctt cgaaaaacca cctccccagg tggttttttc gtttacggag caaaagatta
     1441 catcccacga ctaaggatct caagagatcc tttcaatcac gttcctacta tgccaaagaa
     1501 gtcatgccaa tacgtatccc ctaaccaggg tctactgctc gaaacacact cagttagctg
     1561 aaacaaacta acattagaac aataatctct agtactctga cgttaagcta acaacaaaac
     1621 tagattagga gtaatagatg gcgatctatg ccgtatggaa taacaaaggt ggtgtaggaa
     1681 aaagttatct tacctttcaa ctagcctctg agtacgccag acagaacccg acaaaaaagg
     1741 ttctggtgat tgatctatgc ccgcaagcta actcatcctc aatgttactt ggcgggatgg
     1801 ttaatggcga aaatacgcta aatcaaattc attctgcgac acaaagaaag actatttctg
     1861 gatatattga ggataggatc agaagcccat acattccgac aaacacaggt tctaactacg
     1921 taatcaacgt atctacatac aatagcagaa taccaaataa tctatatctt gttactggcg
     1981 atgaacaatt agaacttcaa gcatcaagag ttgttggagc atcattccca gggcctcacg
     2041 acgcatggcg aacagttcac ctttggatta acgatctaat tagtgacatt tgtaactcat
     2101 gggataatga cgacagctgt gtgttcatcg actgcaaccc tagcttctct atttatactg
     2161 agctagcgtt aaccgcagca gaacgcctct taattccatt ctctgctgat ggttcatcaa
     2221 aaagagcagt taaagctgtt ctttctttag tttatggcga gcgccgtcat cagaacgaac
     2281 cacagtcaga tttctattta aacagcaatc gctactctat gtcattaccg caaatataca
     2341 tgtatgtagg taatagatta acccaaatga acaactcatc tgctagcgca tttaagactg
     2401 tggtaacaga gattggcgat gagatttgga aagtgtggca aacaaaacca agtctgttct
     2461 gcatccatcc aaatggaaac tcaacgccga ataataaaaa atcatttagg aacatgttcc
     2521 agtatgaagt gaatgatgca aatacagcat ctgtcgtatc aggagcactt gggattccaa
     2581 ttgccacgct aaccgcagga aataaaaacg tttcaggaag aacaataaag gtaaatcaaa
     2641 cacagcttga taagcaagtt cccaacattg tagctcttgc cggtatgatt gagtaaaaac
     2701 aggcccttga aagggcctgt ttttttattt gtttttcttt actgtttgta acgccttgcc
     2761 tacaccggac gccatttcat tgattatatt atcttttttt tcaatgattt cattgagtaa
     2821 ttcgttttca ttttccagtt tattcaaagc attctgacta tcgtcaatgg catcatcgta
     2881 tccttcagaa taaccatcca tccagccaag agtataagtc tggtccagaa ggtcagcttg
     2941 cttatcttgt aggtctttat tctgatcgtt attaaagccc atgtttgttc ctcatttgtt
     3001 ggcgcatttg agttctcagt ccagaaggaa ttgcatttct aagtttctca ctcagcctgg
     3061 ctggagcatt tttacttgaa acagcgctac cattagcatc aacagcatca ttcttttttc
     3121 tgtagtcact aatattttta acgttatctt cagtcataga acactactcc tatcgctgtg
     3181 aataacccaa tatacactgg agaattgaac ataacatccc ttgcccgcac ccccgcaaag
     3241 gccctcagcg cgatcttagc gcgtccgggc caaaaggcat ccctttctct gcccgaaacc
     3301 gcgaaaatcc gtcctgatta gtttccccgg actgcatagc catgcagccg ggtgaatggc
     3361 tcaggctttc aatgtagatc ttcacctaaa gccctatttt acctgattca tcaaaaactc
     3421 ggagcagaga gtcttaccac taacggtaaa acaggcaatg atcgagattt tatcgcataa
     3481 aattattgat accttaaatt ctatcgtata gattaagtaa aaaatgagat tcattcacct
     3541 agtaaggatt tctatatgaa agatatgaag gctgttgttg tttttaccgg aaaagatttg
     3601 aacataatga gaactgaggg ggggtcaggc tactggcatg ccagaacaga caggcttaac
     3661 gatgccgaat acctcatagc agtaagaaac agaagggaaa cgtgggcagt aaaagacctg
     3721 gaacacggca cagccttcct gattgcaaaa attaccgggt gctttaaaaa tcccgattac
     3781 gatgacagga acgtcataac ctttgatgag tatgcagaaa ttcactctcc agacgcatgg
     3841 aaaatgctaa ccggtggtca gcgctatcct gttgcttacc tgaacgcaca ggaagccttt
     3901 ttacgtattg gggtaacacc ggaacaactg gaatggaaga aattccatcc ttcatcccca
     3961 tcgcttccta atgcagtggt tcctagtctg gctgaagaga aaacagaaaa actctccctt
     4021 aacgaggcaa ttgaaagagc caaaaaggat attagcaacg caacaggaat tgatagctca
     4081 gccataacaa taagcatcaa gatctgatgc agcgtgaaca acaggatagc agcctcacgt
     4141 tctaacatgc gagaactgaa tctgtgcgcc agaagtaagc tcatgctttt ccggcgcaca
     4201 gattcaaagt gacggaccgt tgtacgtccg ctgtcgctgc gatcgttcca gctccagcgc
     4261 tttctggtgc tgcgccgcgc gcgcctgctc ccggtgtgcc tcgacacagt tcagccttgc
     4321 gacaaccggc gcagctgctc gctcaaactc tgcacctgcc tgctcaagcc cgtgacgcgc
     4381 tcgctcagcg ccgcgttctc ccgttgcata agaccagaca tcgtccgcca ttccgcgaag
     4441 gcgttctccc actcgtccag ccttttcgag tagtcctgct gtagctgctc taatgcgctc
     4501 agcaactgtt tttccagctc tgtcatgtgc tatttccccg ccagtatcat ccagctcgaa
     4561 tcctctccga accgtcccgc ttccgggttc accctcacgc agcggcgtcc ctgctctccg
     4621 caggtcgaga gctgcacgcc gctgttcctc tcggacagta tggcctgcgt actcttctgc
     4681 tcccggatgg tcgtgtaatt gtcgagtatc tgctgcccct gccaccacag aatgcccgcg
     4741 ctcgaggcga tcagcaggac ggagaccagg acgatggtca gccacgtctg gctgaccatg
     4801 cgcagcatcc ctttcgtgcg ctggctcatg gctgaggaca gcttccggtc gtggtcgagg
     4861 atggcggcgc tgattctctt ctcgctttcg ctcagttccg ctctgacaga cttctcgtgc
     4921 tcgctgaagg cggctttcag catctcgccg gtactctgct gctgcgcttt cgatttctgc
     4981 tctaagtcct tcgccagcgt taaaagactg ttcatagatg gctcccttca gtcggatgtt
     5041 tcgccccccg tccgggtcgg caatgctgat gctgcttttt gtggtgcgga tcacctcaaa
     5101 acctgcgctt tccagcgcct cagtgacgtc ctgacgcgtt ttaagctccc cggacgaggc
     5161 taaggccagt aaaccccgcg taatcgcctg agctgcttcc tgcttcgctt ccggcagcgc
     5221 ggacggcgtg accagcgccc gccggttttc cggcgcgttc gggtcgtgca gtcccagcct
     5281 gccgttaacg atggtctgcc aggcatcgat gcgcggacgg tcggcgcggt cgtaatacgg
     5341 ctggagacgc ctgccggtca gcagctccgt atttgggatc aggaagttca gctccagccg
     5401 ccccttgtcc tggtgctcaa cccacagcac gctgtactgg tctttatcaa gtccgggcat
     5461 cagaacccgc tcgaagctcg ccatcagctt ttcacgctgg ccgggcggta aatccttttc
     5521 ggc
//
