LOCUS       NZ_CP126855             6075 bp    DNA     circular CON 21-APR-2024
DEFINITION  Enterobacter hormaechei strain Ehh_7 plasmid pEh7_4, complete
            sequence.
ACCESSION   NZ_CP126855
VERSION     NZ_CP126855.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35394390
            Assembly: GCF_032202685.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 6075)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss
            companion animal clinic and their genetic relationship to clinical
            human isolates
  JOURNAL   J Antimicrob Chemother 78 (12), 2950-2960 (2023)
   PUBMED   37923369
REFERENCE   2  (bases 1 to 6075)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2023) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_032202685.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 14:01:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,106
            CDSs (total)                      :: 4,993
            Genes (coding)                    :: 4,900
            CDSs (with protein)               :: 4,900
            Genes (RNA)                       :: 113
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 93
            CDSs (without protein)            :: 93
            Pseudo Genes (ambiguous residues) :: 0 of 93
            Pseudo Genes (frameshifted)       :: 25 of 93
            Pseudo Genes (incomplete)         :: 69 of 93
            Pseudo Genes (internal stop)      :: 13 of 93
            Pseudo Genes (multiple problems)  :: 13 of 93
            Pseudo Genes (short protein)      :: 1 of 93
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP126855.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6075
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Ehh_7"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="pEh7_4"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-12-07"
     gene            1..915
                     /locus_tag="QPR83_RS25360"
                     /old_locus_tag="QPR83_25345"
     CDS             1..915
                     /locus_tag="QPR83_RS25360"
                     /old_locus_tag="QPR83_25345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_032333168.1"
                     /translation="MSAALQYFDENLPHRPYHTDDLAFGLRISGKGRALLARYIQQNQP
                     HAQFWLVFDVDREGAAIDWSDRNAPAPNITVKNPVNGHAHLLYALNIAVRTAPDSSVKA
                     LKYAAAIERSLCEKLCADVNYSGLICKNPFHLEWQVMEWREEAYTLDELADYLDLSASA
                     RRSIDKHYGMGRNCHLFEMTRKWAYRAIRQGWPEFSQWLDAVIQRVEMYNASLPVPLSP
                     PECRAIGRSIAKYTHRNFTPETFAQYVADTHTPEIQAARGRKGGSKSKRSTVATSARTL
                     KPWEALGISRAWYYQLKKRGLVE"
                     /name="replication initiation protein"
     gene            complement(1119..1517)
                     /locus_tag="QPR83_RS25365"
                     /old_locus_tag="QPR83_25350"
     CDS             complement(1119..1517)
                     /locus_tag="QPR83_RS25365"
                     /old_locus_tag="QPR83_25350"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001560793.1"
                     /translation="MRISNIEWLKKRIGFIRKLGEQTARQRQIIDLLDNEAGLTEQERK
                     LLHVLATAEKNDLQAQESERKQAVQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELCYKKDRILQALKELKYDLETSPNPDA"
                     /name="hypothetical protein"
     gene            1694..2620
                     /locus_tag="QPR83_RS25370"
                     /old_locus_tag="QPR83_25355"
     CDS             1694..2620
                     /locus_tag="QPR83_RS25370"
                     /old_locus_tag="QPR83_25355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_023148976.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIERKGEYAKRKDLEYTEHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTPEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIDGGEQPHAHIMMSQRVNDGIDRTPEQYFRRYNARYPERGGAKKDSGSLT
                     LTQQKEQLRELRKRWEVKHNEHMRKHGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGHDIREWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQDRTEPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            2623..3156
                     /locus_tag="QPR83_RS25375"
                     /old_locus_tag="QPR83_25360"
     CDS             2623..3156
                     /locus_tag="QPR83_RS25375"
                     /old_locus_tag="QPR83_25360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031944069.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQRLDVAGLIGERISQDFQRLEESVANMKANADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFSVLGWGMKTILDRNYNATAAVYQKVVTLED
                     KLAEKPVTGKSRKN"
                     /name="hypothetical protein"
     gene            3377..5107
                     /locus_tag="QPR83_RS25380"
                     /old_locus_tag="QPR83_25365"
     CDS             3377..5107
                     /locus_tag="QPR83_RS25380"
                     /old_locus_tag="QPR83_25365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E7"
                     /protein_id="WP_021530049.1"
                     /translation="MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNP
                     WGGGSGSGVHWGGGSGHGNGGGNSNSGGGSNSSVAAPMAFGFPALAAPGAGTLGISVSG
                     EALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQ
                     VSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGV
                     PSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPVYVS
                     VTDVLTPAQVKQRQDEEKRLQQEWNDAHPVEVAERNYEQARAELNQANKDVARNQERQA
                     KAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDV
                     NNKKAAFDAAAKEKSDADVALSSALERRKQKENKEKDAKAKLDKESKRNKPGKATGKGK
                     PVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNN
                     NDRMKVGKAPKTRTQDVSGKRTSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIHRGK
                     "
                     /name="colicin E7"
     gene            5109..5372
                     /locus_tag="QPR83_RS25385"
                     /old_locus_tag="QPR83_25370"
     CDS             5109..5372
                     /locus_tag="QPR83_RS25385"
                     /old_locus_tag="QPR83_25370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_001560791.1"
                     /translation="MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKIT
                     EHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG"
                     /name="bacteriocin immunity protein"
     gene            5434..5577
                     /locus_tag="QPR83_RS25390"
                     /old_locus_tag="QPR83_25375"
     CDS             5434..5577
                     /locus_tag="QPR83_RS25390"
                     /old_locus_tag="QPR83_25375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724569.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_001560790.1"
                     /translation="MKKITGIILLLLAAIILAACQANYIRDVQGGTVSPSSTAELTGVE
                     TQ"
                     /name="colicin release lysis protein"
     BGC             1..6075
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          2..776
                     /name="Col156"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.139"
                     /coverage="83.0"
                     /evalue="0.0"
     Typing          1695..2617
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.104"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgagcgccg cgcttcaata cttcgacgaa aatttacccc accgtcccta tcacacggat
       61 gatctcgctt ttggtcttcg catctccggc aaagggcgtg cgcttcttgc gcggtacata
      121 cagcagaacc agcctcatgc acagttctgg ctggtttttg acgttgaccg cgagggggca
      181 gcgattgact ggagcgaccg gaacgctccc gcgccgaaca tcaccgtaaa aaatcctgtg
      241 aacggtcatg ctcacctgct ctacgcgctc aatatcgccg tgagaaccgc gccggacagc
      301 tcggttaagg cgctgaaata cgccgctgcg attgaacgtt cgctgtgtga gaaactttgt
      361 gcggatgtga actacagcgg actgatttgt aaaaatccgt tccacctgga atggcaggtg
      421 atggagtggc gagaggaagc ctataccctc gatgaactgg ctgattatct cgatttgagc
      481 gcctcagcgc gccgtagcat cgataaacat tacgggatgg ggcgaaactg ccacctgttc
      541 gaaatgacgc gcaaatgggc ttacagggcg attcgtcagg gctggcctga attctcacag
      601 tggcttgatg ccgtgattca gcgtgtcgaa atgtacaacg catcgcttcc cgttccgctt
      661 tcaccgcctg aatgtcgggc tattggcagg agcattgcga aatacacgca caggaacttc
      721 acgccggaaa ctttcgcaca gtatgtggct gatacgcaca caccagaaat tcaggctgca
      781 cgcggtcgca agggcggttc taagtctaag cgcagcacag tggctacatc tgcacgcacg
      841 ctgaaaccgt gggaggcatt agggatcagt cgcgcctggt attaccaact gaaaaaacga
      901 ggtctcgtag agtagaccaa ataagcctat atcagataac agcgcctttt tggcgtcttt
      961 ttgagcagca ggttttttgc cgtttttccc cgttcagccc tgcaatggtg ctgttttccg
     1021 catgattgcg ctggtagtgc tcgccgcagt ctcatgaccg agcgtagcga gcgaatgagc
     1081 gaggaagcac cagggaatcg gaacacggat ggaggcactt acgcgtctgg gtttggggat
     1141 gtctccagat cgtacttaag ttccttaagt gcctgtaata tcctgtcttt tttatagcat
     1201 agctcgcctg tttttgtgtc taccagtcct gcttcgatca gtagcccagc cgcgagaaag
     1261 agccggtgat tgcgttcccg tcgttgtttt tttccctcga ttcgtttttg gaccgcctgt
     1321 tttcgttcgc tctcctgtgc ctgtaagtcg tttttttccg ctgttgccag tacgtggagg
     1381 agtttgcgtt cctgttctgt gagtcctgct tcgttgtcga gcaggtcaat aatctgtctc
     1441 tgtcgtgcgg tctgttctcc gagcttcctg atgaatccga tccgtttctt cagccattcg
     1501 atgttgctga tgcgcatgtt cgtggtgctc cctggtgttt tttgcggtgt gttgtggtcg
     1561 tgcagtatat cgcttgcggt cggtgggtgc aggggggtat cttccgtgct aattcgtaaa
     1621 attagaagga agcgcactta tatgtttctc tccttcgtcg agaaacagtg cgctcctgcg
     1681 gagggctgaa accgtggcaa cctatcacct cagcgtcaaa tttggaggca agggacaggc
     1741 tgcaaaccac gccgattaca tcgagcgcaa aggggagtat gcgaaacgga aagatctgga
     1801 atacacggag cacggaaaca tgccggaatg ggccagggat aatccttccc atttctggca
     1861 ggcggctgac cagtttgaac gtgcgaacgg ttcgacttat cgggaactgg aaatcgcgct
     1921 gccccgtgaa ctgacaccgg aacagcgcct tgaactggtg caggattttg tacgtcagga
     1981 agccggcgaa cggcacgcct ggagttttgc cattcacaat ccgaaagcga gcattgacgg
     2041 cggcgaacag cctcatgcgc atatcatgat gagccagcgt gtgaatgatg gcattgaccg
     2101 tacaccggaa cagtatttcc ggcgctataa cgccaggtat cccgagcggg gaggtgcgaa
     2161 aaaggattcc ggaagcctga ctctcactca gcaaaaagag cagttgcggg aattgcgaaa
     2221 acgctgggag gtgaagcaca acgaacatat gagaaagcat ggctttgaaa ggggcttcat
     2281 tgactgccgg acgctgaaag aacagggcat tgaacgacgt cccgaagtgc atctgggttt
     2341 tgaagctgcc ggacggcttg atgatgccca gcgtcatgac atcatgcaaa aacggtctga
     2401 accggactat tcccgccatc ttgaacaggc gcgaacggtc gggcatgaca tcagggaatg
     2461 gctggacact ccggttaagc aacatgaact ggtcagaagg cttcaacatg atgttgcgcg
     2521 ggagcatggc tttgacatga gagacagagt gagcagacag gaccgaactg aacctgaacg
     2581 ggttaaatca ccgtcacgtg gattttctat gggattctga acatggccag cacagaagaa
     2641 aaattactca cgctcctgtt atcggtggag catctgcaac ataccgcaat ggagcaacag
     2701 aaagctgttg ctgattctct ggctgtggca agggaaacac ttcgcggata tcgggatatt
     2761 tctgacggtg tggcaaaaca ggtcagggat gaagtcagaa acgaagtgca gaggctggat
     2821 gttgcagggc tgataggtga gcgcatcagt caggattttc agcggctgga agagtcagtc
     2881 gcaaacatga aggcaaacgc ggatgccctg aacagggata ttgcgacaat tcacagcaat
     2941 atcgtgcagg aatacaacac ccttaaaggg tatagctgga aatggctggg tggggtgtca
     3001 gtggcctttc tggttatgtt cagtgtgctc ggatggggga tgaaaacaat tctcgacagg
     3061 aactacaacg ccacagcggc ggtgtatcag aaagttgtga cactggaaga taaactggcg
     3121 gagaaacctg tcacgggtaa gagccggaaa aactgacgcg cttcgtttgt ccaacgcctc
     3181 acggaccgcg aaaggatttc gcgaaccgtt caccgtttcc atgagtgact cctccgaact
     3241 gccaaaaaat atccctccct gacttgacag agaaaataat ggcgagtact ttttgatctg
     3301 tacataaaac cagtggtttt atgtacagta ttaactatgt aattaattgt tttaacgctt
     3361 aaaagaggga atttttatga gcggtggaga tggacgtggc cacaacagtg gcgcacataa
     3421 cacaggtggt aacattaatg gcggccctac ggggcttggt ggaaatggtg gggcttctga
     3481 cggctccgga tggagttcgg aaaataaccc atggggtggc ggttccggta gtggtgttca
     3541 ctggggaggt ggctccggcc atggcaatgg cggggggaat agtaattccg gtggtggcag
     3601 caattcatcc gtagcagcac ctatggcatt tggttttcct gctttggctg ctcctggtgc
     3661 cggaactctt ggtatttccg tatctggtga ggctttatct gcggcaatag cggatatctt
     3721 tgcagccctg aaaggtccgt ttaaattcag cgcatggggt attgcgcttt acggcattct
     3781 gccatctgaa atagcaaaag atgacccgaa tatgatgtca aagattgtga cgtcattacc
     3841 ggcagaaaca gtgacgaatg ttcaggtcag tacacttccg ctggaccagg caactgtcag
     3901 cgtgacgaaa cgtgtgacag atgttgtgaa ggacacacga cagcatattg ccgtagttgc
     3961 aggtgtgcct atgagtgtgc ctgttgtgaa tgccaaacca acacgtactc caggtgtatt
     4021 tcacgcatca tttcctggtg tcccttctct gacagtcagc actgtcaaag gccttccggt
     4081 gtcaacaacc cttccccgtg gtattacgga ggataaaggc cggactgccg ttcctgcggg
     4141 atttaccttt ggtggtggtt cacatgaagc ggtgattcgc tttccgaaag aaagtgggca
     4201 gaagccggtt tatgtatcag tgacagatgt tcttacccca gcacaggtaa aacaacgtca
     4261 ggatgaggaa aaacgcctcc agcaggaatg gaatgacgca catccggtgg aagtggctga
     4321 acgcaattat gaacaggccc gcgcagaact gaatcaggct aataaagatg ttgccagaaa
     4381 ccaggaacga caggctaaag ctgttcaggt ttataattct cgtaaaagtg aacttgatgc
     4441 agcgaataaa actcttgctg atgcaaaggc tgaaataaaa caattcgagc gatttgcccg
     4501 agaaccaatg gctgctggtc acagaatgtg gcaaatggca gggcttaagg cccagcgggc
     4561 acagacggat gtaaataata agaaggctgc atttgatgct gctgcaaaag aaaagtcaga
     4621 tgctgatgtt gcattgagtt ctgcgttgga gcgccgcaaa cagaaagaaa ataaagaaaa
     4681 ggacgctaaa gccaaattag ataaggagag taaacggaat aagccaggga aggcaacagg
     4741 taaaggaaaa cctgtcaata ataagtggtt aaataatgca ggtaaagact taggttctcc
     4801 tgttccagat cgtatagcta ataaactacg tgataaggag tttaaaagtt tcgatgattt
     4861 tcgtaagaaa ttctgggaag aagtgtcaaa agatcctgag ttaagtaaac aatttagtag
     4921 gaacaataat gatcgaatga aggttggaaa agcgcccaag actagaaccc aggatgtttc
     4981 agggaagaga acttcattcg agcttcatca tgagaagccg atcagccaaa atggtggtgt
     5041 ctatgatatg gataacatca gcgtggtaac acctaaaagg catattgata ttcaccgagg
     5101 taaataatat ggaactgaaa aatagtatta gtgattacac agaggctgag tttgttcaac
     5161 ttcttaagga aattgaaaaa gagaatgttg ctgcaactga tgatgtgtta gatgtgttac
     5221 tcgaacactt tgtaaaaatt actgagcatc cagatggaac ggatctgatt tattatccta
     5281 gtgataatag agacgatagc cccgaaggga ttgtcaagga aattaaagaa tggcgagctg
     5341 ctaacggtaa gccaggattt aaacagggct aaaatatgaa tgccggttgt ttaaggatga
     5401 atgactggca ttctttcaca acaaggagtc gttatgaaaa aaataacagg gattatttta
     5461 ttgcttcttg cagccattat tcttgctgca tgtcaggcaa actatatccg tgatgttcag
     5521 ggcgggacag tatcaccgtc gtcaactgct gaactgaccg gagtggaaac gcagtaacct
     5581 gcaatcctca tttgacaaga acaaagcgtg tcaggctgat tctgacgcgc tttttttgtt
     5641 gaagtgccac aaaaattcca tgtgggagat gggatctaaa atctccgtgc agaaccttcc
     5701 atcaggaggg agaaaacttt tcgttttgag ccgttcggtg ttcagaacgc acgaaaccga
     5761 tcgcacatcg ctttcgtgca tagttatgca ggcccctaaa aacgattctg acgcattttt
     5821 ctggttcagc ctggtgtttc cttgtctttt tgcgtttttt gcgtcagaaa gcgattgagc
     5881 gcgttttagc ggtgcgttta acgggagtta tggtaaatgg atcgggtttt cgggaaggtt
     5941 cgacaggatt tgccgttggg tgtagtgtaa gcgactgaaa aacaaacgcc cctgaaatca
     6001 tgtccagatc cggcaagatt caacatgaaa tacagagggc gtgtaggtcg cataacccgg
     6061 agagaatcgt aacac
//
