LOCUS       NZ_CP126802             6165 bp    DNA     circular CON 21-APR-2024
DEFINITION  Enterobacter hormaechei strain Ehh_15 plasmid pEh15_4, complete
            sequence.
ACCESSION   NZ_CP126802
VERSION     NZ_CP126802.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35394404
            Assembly: GCF_030848085.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 6165)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss
            companion animal clinic and their genetic relationship to clinical
            human isolates
  JOURNAL   J Antimicrob Chemother 78 (12), 2950-2960 (2023)
   PUBMED   37923369
REFERENCE   2  (bases 1 to 6165)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2023) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 95x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030848085.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 14:24:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,415
            CDSs (total)                      :: 5,298
            Genes (coding)                    :: 5,168
            CDSs (with protein)               :: 5,168
            Genes (RNA)                       :: 117
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 36 of 130
            Pseudo Genes (incomplete)         :: 100 of 130
            Pseudo Genes (internal stop)      :: 19 of 130
            Pseudo Genes (multiple problems)  :: 22 of 130
            Pseudo Genes (short protein)      :: 1 of 130
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP126802.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6165
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Ehh_15"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="pEh15_4"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-10-31"
     gene            join(6121..6165,1..174)
                     /locus_tag="QPR56_RS27015"
                     /old_locus_tag="QPR56_27015"
     CDS             join(6121..6165,1..174)
                     /locus_tag="QPR56_RS27015"
                     /old_locus_tag="QPR56_27015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_234784325.1"
                     /translation="MFGFSSGALMTFNDDERHLLVSVVSGWLRRAEGDAGAMMLDAYRQ
                     ILSETEPAARAVMLEFLKSVRIHYVSS"
                     /name="hypothetical protein"
     gene            complement(296..3193)
                     /locus_tag="QPR56_RS27020"
                     /old_locus_tag="QPR56_27020"
     CDS             complement(296..3193)
                     /locus_tag="QPR56_RS27020"
                     /old_locus_tag="QPR56_27020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="WP_001553819.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRRP
                     ENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQHM
                     DTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVSTIE
                     RLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGNNSAA
                     ANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWAILAVC
                     VVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALGASLLEA
                     RSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRYAPRMLRC
                     LKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDTRLWEVAVL
                     FHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLADRKARLTIA
                     LKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPSVRITDMLLEV
                     DAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTHDYWQLSRLARW
                     HVESEAMNQALAIVVAAQGKLPMSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSV
                     PGLKAYTHVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLF
                     GASSLLGYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAA
                     TMTAGKIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLN
                     KGEAHHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRN
                     EGLDVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
                     /name="Tn3-like element Tn5403 family transposase"
     gene            3288..3893
                     /locus_tag="QPR56_RS27025"
                     /old_locus_tag="QPR56_27025"
     CDS             3288..3893
                     /locus_tag="QPR56_RS27025"
                     /old_locus_tag="QPR56_27025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000509965.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETGS
                     GTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLRELENWKVSVIAMNGM
                     AFDLSSPYGRMLATFLSGIAEFERDLISERVKSGLAVAKARGKRLGRQAGVRPKSDRLL
                     PKVVAMRAEGRSYRWIARELGISKNTVADIVQRHRANA"
                     /name="recombinase family protein"
     gene            complement(4141..4326)
                     /locus_tag="QPR56_RS27030"
                     /old_locus_tag="QPR56_27030"
     CDS             complement(4141..4326)
                     /locus_tag="QPR56_RS27030"
                     /old_locus_tag="QPR56_27030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_032673404.1"
                     /translation="MTRQESAALNMAKFIRSQTLLLLERLEQMDLDEAAGCCEHLHDQA
                     EALYAMLNAQIGEKDA"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(4692..4919)
                     /locus_tag="QPR56_RS27035"
                     /old_locus_tag="QPR56_27035"
     CDS             complement(4692..4919)
                     /locus_tag="QPR56_RS27035"
                     /old_locus_tag="QPR56_27035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010615788.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="WP_021243043.1"
                     /translation="MKKIFVSVFAAAVALSALTGCTRTSYAIHTNDGRTIVSDGKPKES
                     DSGLLGYTDANGVKQQINKTDVKEVSEIPH"
                     /name="YgdI/YgdR family lipoprotein"
     Typing          4007..4094
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="94.382"
                     /coverage="100.0"
                     /evalue="1.5000000000000001e-30"
     Typing          5842..6011
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.698"
                     /coverage="98.0"
                     /evalue="2.0600000000000002e-57"
     Typing          complement(5335..5917)
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="87.331"
                     /coverage="97.0"
                     /evalue="0.0"
ORIGIN
        1 gagcgacacc tgcttgtgtc cgttgtttcg ggctggctcc ggcgtgccga aggggatgcc
       61 ggagccatga tgctggatgc ataccggcag attttgtctg aaaccgaacc ggccgcaagg
      121 gcggtcatgc tcgaatttct taaatcagtt cgcattcatt acgtttcgtc ctgagcattt
      181 cctgaagcat ttcctgaatt tttgtccata ctcaatccag gcggccgtca cggacggtgg
      241 tcgtcgttcc atgatgctgt taggggtcgg ttccggctga gggcgaaatg acaccctaag
      301 ctttcggttc cttgggccaa agatattcgc cagtcagtag aatgtgcgcc cagcccaatg
      361 gggatatgtg gggaagaaat tcagggggaa catccaaccc ttcgttccgc cgctccgtga
      421 cggcatgacc aagatggacg gtattccagt aaatgatcac cgcagtcaat aaattgagcc
      481 cagcgattcg gtagtgctgc ccctctgtcg tgcgatcgcg aatttccccc tgcctcccga
      541 tacggagcgc atttttgagc gcatggtggg cctctccctt gttaagaccg atctgagcac
      601 gccgctgcat gtccgtatcc aggatccact caataatgaa aagggtccgt tcaatacgac
      661 caacttcacg aagcgcaact gcaaggttgt tttgtcgtgg gtaagaagcg agcttgcgca
      721 ggagttggct gggcctgatt ttgccagcgg tcatcgtcgc ggcacaacgg aaaatatcag
      781 gccagttcgc aacgataaga tcctcccggg cttttccacc taccaacttg cgtaactccc
      841 tgggggtcgt atcgggatta aatacgtaca accgcttcga tggcagatcc ctgattcgca
      901 gaacgagatt gtagccgagc aggctactgg ctccgaacaa atggtcggtg aatcctgctg
      961 tatcggcata ctgttcgcga acatggcgac cgacctcgtt catcagtagt ccatcgagaa
     1021 tatacggtgc ctcgctcacg gtcgccggga tcgactgaca agcgaatggc gcgaactggt
     1081 cgcttacgtg agtatacgct ttgaggccgg gaacagaacc atatttggca ttgaccatgt
     1141 tcatggcttc gccatgccgc gctgtcggga aaaactgacc atcgctcgat gctgacgtgc
     1201 ccatccccca gacgcgtgac atcggcagtt taccctgcgc ggccaccaca attgccaatg
     1261 cctggttcat ggcttcgctt tcaacatgcc agcgggcaag gcgtgagagc tgccagtaat
     1321 catgcgtgtt tgtagcttcc gccatcttac gcaggcccag attgagccct tcagcgagca
     1381 ggacgttgag cagaccgatc cggtcgcgac atggagcccc ggttctcaga tgggtaaacg
     1441 catctgtgaa accaagggct gcatcaactt caagcagcat gtcggtaatc cgaacggacg
     1501 gcattcggcg atacagatcc agtatgagtg cctcggcacc atccggcacg tctgctgtca
     1561 acctgtcgat ccgcaacgtt ccatcttcta tgctaccgtg cggaatagtg ccgttacggg
     1621 cagcccgggc cagccgctta agagcgatcg tgagtcgcgc ctttctgtct gccagccaat
     1681 cctgtgggtt ggaaggcacg gccagttttg cattttcctg cgccgcgatc atcggcacca
     1741 gtacctgctt gaggtcacca tagcggcgcg aatgagcgag ccagacatct ccggaacgaa
     1801 aagcatcccg gaggtgaaag agtaccgcca cttcccaaag acgggtatct cctttttcct
     1861 gagctcgtaa atgacggttc catttggagc tgggccgcag gaaacgcctt tctggcgatg
     1921 caacaccttt catctctccg atcgacaaag ctgctgctac caatggtccg gcgaccggcg
     1981 cggcttcgag cttcagacag cgcaacatgc ggggcgcata acgacgaaag cgatggtatc
     2041 cctgcccgac atatgcaaga ggctcatcgg ctagcgtgtt gctgagttga gtccctgtcg
     2101 ctaccagttg agcgagccgg tcccatgcaa ccgaactggc gacagccatc tccagcgggg
     2161 ttccgtcact gcgggcctca agcaacgaag ctcccagcgc ggtgaaggta cggatcgtat
     2221 ccgtgagtgt ggctttagag ccggaaattg tttcgtcatg ctggcgcttc gcttcccgcc
     2281 aggtttttcc tacgatcctg tcatgggttt cgactatggc atcagcaatc gccgcttccc
     2341 actccacaac acagacggca aggatcgccc agcggcggtc cgaagtgatg tcacgcaaac
     2401 cgtcggtgaa gtagcgttca ccctgccgac gcagccgggc aatgcgatgg gcaggtatgc
     2461 tggccaaagc actatgattg atattcaggg tacgcagaaa ttcgagcctg tcgagcaaac
     2521 ggttagcagc agccgagttg ttaccaacct cgaagttgcg aagccagatg aaacgactga
     2581 tattgccggc gagcatttca ctcagaagtt tgtccaggtg atcgcgaaca tccgctgtta
     2641 aattttccgc aatccgcgtt tcaatccgcc gctcagcggc gaccagagca tccgcgcaca
     2701 agcgctcgat tgtcgatact gcgggcagaa tggtggaagt ttcccgacac cgcacaataa
     2761 aacgatgagc aagatcctcg tttgatctgg catcttcggc ctggccgaaa gtccactccc
     2821 gcagatcacg ggcaccacgg cccgtgaagg tcttgtagcc gtaaatttcg cgcagcgtgt
     2881 ccatgtgctg ctgacgggtt tggcgccgtg tggcataagt gagaagcgca tcagccggaa
     2941 ctccaagctg agcaccgacg aaggaaagga cttcacgcgg gatcatctca ccaggagcca
     3001 gtgcacggcc cggatatcgt aaggcacaaa gttgcagggc aaagccaatc ctgttttccg
     3061 gtctgcggcg ctgcctaatg ttttccaggt catcatcgcc cagcgtgtag aacttcagta
     3121 gcgacagttc gtccgtgggc agatcgaaca gcgctgctcg ctgccgttcg gtgaaaatat
     3181 ggcgtcgtga catacaaatt cgtccctttt gaagtatagt ctgttttgga caacagccag
     3241 cccatataaa tcagggcgtt ccgatacaaa aatccaggag ggttcaattg ggacatcgtg
     3301 ccgccattta ctgccgggtt tcaacagcgg atcagtcttg tgaacgccag gaatttgatc
     3361 tgcgagcctt cgccggctgt gccggctacg acgtggtggg aatatttaag gaaacaggtt
     3421 caggaactaa actcgaccgg gccgagcgaa agaaagtcct ggcgcttgcc cagtccagac
     3481 aaattgatgc aatcctggtc actgagcttt cccggtgggg gcgctcgacg ctcgatctgc
     3541 tcaatacgct acgtgaactg gagaactgga aggtttccgt gatagccatg aatggaatgg
     3601 cgttcgatct ttcgtcgccg tatggacgaa tgctggcgac gtttctttcc ggcattgcgg
     3661 agtttgagcg ggatctcatc agcgagcggg tcaagtcagg ccttgctgtt gcgaaggcac
     3721 gtggtaagag gcttggtcgt caggccggag tgcgaccaaa atcagaccga cttttgccta
     3781 aggtggttgc gatgagggcc gagggacgca gctatcgctg gatcgcacgc gagctcggta
     3841 tcagcaagaa taccgtcgct gacatcgtgc aacgacacag agctaacgct tagggtgtca
     3901 tttcgccctc agccggaacc gacccctgtt atggaagatt gagagtaatc taacttgatt
     3961 gagttccggg cgtgtcgccc ggtttttttt gctgtttccc ggtgtccgct cccggacagg
     4021 atgtgcattt gtaataccgc gcacgcggcg gcatcacaaa taccccgttc agggctgcgc
     4081 cccgacaccc cgccatcgcc tcacggccgc gcactgaatt gcgcacccgt tcaccgattt
     4141 tcacgcatct ttctcgccta tctgtgcgtt cagcatggcg taaagcgctt cagcctgatc
     4201 gtgcagatgc tcacagcagc cggctgcctc atccagatcc atctgttcga gccgttcgag
     4261 gaggaggagt gtctgtgagc ggataaattt ggccatgttg agggcggcgg attcctgtct
     4321 ggtcactggt gattttcccc gtctggtgat gatttttgcg tgaaaagagc atgccgtcat
     4381 tctggtgcat agtcatgcat gccgttaaaa tttaacaggc gcgtttctga cgggttccgg
     4441 ggtggtttgt tgtggttttt gtcatggttc cgtcagaaac gcgctgagcg cgtctgaggc
     4501 ggtgcgggca acggatgtta tggtaaattc ttgggggctt gattataaaa taccgcactt
     4561 cctcttatgt cttgtgcttt ttagacaacc ctgaaagctt ttagctttgg tgatgcaatt
     4621 tgctgggatt ttggcggaga accacaggta aagaaaaagg ccacattagc ggcctttttc
     4681 ggagaatatg ctcagtgcgg aatttcggag acttctttaa cgtcggtttt attgatctgc
     4741 tgtttgacac cattcgcgtc tgtatagcca agcaggcctg agtctgattc tttaggtttg
     4801 ccgtcgctga caatagtgcg accgtcattg gtgtgtatgg catagcttgt gcgcgtgcag
     4861 ccggtgaggg ctgaaagcgc aactgccgct gcgaacactg aaacaaaaat ctttttcaaa
     4921 gccagctcct tttatccata tcagttttgg tcactaacca tctaactata ggttattttt
     4981 tatgtgaaaa gaggcttgat ggtgggctgt atatcgagtt aggcgcgagg tgctatggtc
     5041 aaagtgtggt gtcaagcggg gaggaggctt atatgagatg taatccagca gatacatata
     5101 ccaagatgat ttaagtattc ctctttgtga ggttggatgt ctaatttata aaggatcttc
     5161 ttgagatcct tttttttcgc gcgtaatctc ttgccctgta aacgaaaaaa ccaccctggc
     5221 aggtggtttt tcgaaggtta ggtaatcctg gcagatcccc taaccgtggt aacagtcttg
     5281 tgcgagacat gtcaccaaat ttgtcctttc agtgtagcct cactaaggcc gccacttcaa
     5341 gaactcttga tacatctctc gcacatcctg tttaccaatg gccgttgcca atggcgatta
     5401 gtcgtgtctt tccgggttgg actcaagttg atagttaccg gataaggcgc agcggtcgga
     5461 ctgaacgggg ggttcgtgca tacagtccat cctggagcga actgccttcc cggaactgag
     5521 tgtcaggcgt ggaatgagaa accgcggcca taacagcgga gtgacaccgg taaaccgaaa
     5581 ggcaggaatg cgggggagca cgagggagcc accaggggga aacgcctggt atctttaagc
     5641 cgcatcgggt ttcgccacca ctgatttgag cgtcagattt cgtgatgctt gtcagggggg
     5701 cggagcctat ggaaaaacgg ctttgccgtg gccttatgcc tttttcgcta agaaccttcc
     5761 tggcattctc caggaaattt ctgctctgta cgtaagcccg taccgctcgc cgcagccgaa
     5821 cgaccgagcg cagcgagtca gtgagcgagg aagcggaata tctcctgtat cacatattct
     5881 gctgacgcac cgatgccgcc tttttctcct gccacatgaa gcacttaact gacatccgca
     5941 tccgtgccaa catattaagc cagtatacac tccgctagcg ctgcgtgact ggtccggcgc
     6001 tgcgcccgga acccgcctgt accggttaag cagccgttct ggtctgactg cgattttttt
     6061 cattcctgcc cgctaccctg taaacctttc ttctgcgttg ccgttaacag gaggtaagcc
     6121 atgtttggtt tttcctccgg agccctgatg acttttaatg atgat
//
