LOCUS       NZ_CP126787             3750 bp    DNA     circular CON 21-APR-2024
DEFINITION  Enterobacter hormaechei strain Ehh_17 plasmid pEh17_3, complete
            sequence.
ACCESSION   NZ_CP126787
VERSION     NZ_CP126787.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35394406
            Assembly: GCF_030848065.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 3750)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss
            companion animal clinic and their genetic relationship to clinical
            human isolates
  JOURNAL   J Antimicrob Chemother 78 (12), 2950-2960 (2023)
   PUBMED   37923369
REFERENCE   2  (bases 1 to 3750)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2023) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030848065.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 14:18:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,199
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,978
            CDSs (with protein)               :: 4,978
            Genes (RNA)                       :: 115
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 27 of 106
            Pseudo Genes (incomplete)         :: 75 of 106
            Pseudo Genes (internal stop)      :: 19 of 106
            Pseudo Genes (multiple problems)  :: 14 of 106
            Pseudo Genes (short protein)      :: 1 of 106
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP126787.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..3750
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Ehh_17"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="pEh17_3"
                     /geo_loc_name="Switzerland"
                     /collection_date="2021-08-18"
     gene            complement(join(3071..3750,1..247))
                     /locus_tag="QPR58_RS25985"
                     /old_locus_tag="QPR58_25980"
     CDS             complement(join(3071..3750,1..247))
                     /locus_tag="QPR58_RS25985"
                     /old_locus_tag="QPR58_25980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_014342223.1"
                     /translation="MATYHLSVKFGGKGQAANHADYIERKEKYRDRQDLEYSAHGNMPE
                     WARDNPSHFWQAADQFERANGSTYRELEIALPRELTAEQRLELVQDFVRQEAGERHAWS
                     FAIHNPKASIDGGEQPHAHIMMSQRVNDGIERTPEQYFRRYNARYPERGGAKKDSGSLT
                     LTQQKEQLRELRKRWEVKHNEHMRKHGFERGFIDCRTLKEQGIERRPEVHLGFEAAGRL
                     DDAQRHDIMQKRSEPDYSRHLEQARTVGYDIREWLDTPVKQHELVRRLQHDVAREHGFD
                     MRDRVSRQNRTEPERVKSPSRGFSMGF"
                     /name="MobA/MobL family protein"
     gene            424..822
                     /locus_tag="QPR58_RS25990"
                     /old_locus_tag="QPR58_25985"
     CDS             424..822
                     /locus_tag="QPR58_RS25990"
                     /old_locus_tag="QPR58_25985"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001222916.1"
                     /translation="MRISNIEWLKKRIGFIRKLGEQTARQRQIIDLLDNEAGLTEQERK
                     LLHVLATAEKNDLQAQESERKQAVQKRIEGKKQRRERNHRLFLAAGLLIEAGLVDTKTG
                     ELCYKKDRILQALKEIKYDLETSPNPDA"
                     /name="hypothetical protein"
     gene            complement(1083..2102)
                     /locus_tag="QPR58_RS25995"
                     /old_locus_tag="QPR58_25990"
     CDS             complement(1083..2102)
                     /locus_tag="QPR58_RS25995"
                     /old_locus_tag="QPR58_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001271364.1"
                     /translation="MSAALQYFEENLPHRPYHTDDLAFGLRISGKGRALLARYIQQNQP
                     HAQFWLVFDVDREGAAIDWSDRNAPAPNITVKNPVNGHAHLLYALNIAVRTAPDASVKA
                     LKYAAAVERSLCEKLCADVNYSGLICKNPFHLEWQVMEWREDAYTLDELADYLDLSASE
                     RRSIDKHYGMGRNCHLFEMTRKWAYRAIRQGWPAFSQWLEAVIQRVEMYNASLPVPLSL
                     AECRAIGKSIAKYTHRNFTPETFAQYVADTHTPEIQAARGRKGGKANSSENQSDKGKKS
                     AAVRWTANDDKRRRALDMYILGASTEDIAVAVGVSSRTIRRWMDNSGEWLTKKQIIKC"
                     /name="replication initiation protein"
     gene            complement(2535..3068)
                     /locus_tag="QPR58_RS26000"
                     /old_locus_tag="QPR58_25995"
     CDS             complement(2535..3068)
                     /locus_tag="QPR58_RS26000"
                     /old_locus_tag="QPR58_25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000168772.1"
                     /translation="MASTEEKLLTLLLSVEHLQHTAMEQQKAVADSLAVARETLRGYRD
                     ISDGVAKQVRDEVRNEVQKLDVAGLIGERISQDFQRLEESVANMKANADALNRDIATIH
                     SNIVQEYNTLKGYSWKWLGGVSVAFLVMFCVLGWGMKTMLDRNYNATAAVYQKVVTLED
                     KLAEKPVTGKSRKN"
                     /name="hypothetical protein"
     Typing          complement(1328..2102)
                     /name="Col156"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.907"
                     /coverage="83.0"
                     /evalue="0.0"
     Typing          complement(6..247)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.765"
                     /coverage="99.0"
                     /evalue="1.32e-45"
     Typing          complement(3075..3748)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.778"
                     /coverage="99.0"
                     /evalue="1.0999999999999999e-148"
ORIGIN
        1 ccgctgtcag ttcacggggt aatgcaattt caagttcccg ataggtcgaa ccgttcgcac
       61 gttcaaactg gtcagcagcc tgccagaaat gtgagggatt atctcgcgcc cattccggca
      121 tgtttccgtg tgcggaatat tccaaatcct gacggtcgcg gtatttctct ttgcgctcga
      181 tgtaatcggc gtggtttgca gcctgcccct tgccaccaaa tttaacgctg aggtgatagg
      241 ttgccacggt ttcagccctc cgcaggagcg cactgtttct cgacgaagga gagaaacata
      301 taagtgcgct tccttctaat tttacgaatt agcacggaag ataccccctg cacccgccga
      361 ccgcaagcga tatactgcac gaccacaaca caccgcaaaa aaacaccagg gagcaccacg
      421 aacatgcgca tcagcaacat cgaatggctg aagaaacgga tcggattcat caggaagctc
      481 ggagaacaga ccgcacgaca gagacagatt attgacctgc tcgacaacga agcaggactc
      541 acagaacagg aacgcaaact cctccacgta ctggcaacag cggaaaaaaa cgacttacag
      601 gcacaggaga gcgaacgaaa acaggcggtc caaaaacgaa tcgagggaaa aaaacaacga
      661 cgagaacgca atcaccgact ctttctcgcg gctgggctac tgatcgaagc aggactggta
      721 gacacaaaaa caggcgagct atgctataaa aaagacagga tattacaggc acttaaggaa
      781 attaagtacg atctggagac atccccaaac ccagacgcgt aagtgcctcc atccgtgttc
      841 cggttccctg gtgcttcctc gctcattcgc tcgctacgct cggtcatgag actgcggcga
      901 gcacgaccac ctcaatcatg cggtaagccg caccattgct gggctgagag gagaaaaccg
      961 ccggaaagcc cgctgctcaa aaagacgccg aaaggcgctg ttatctgata taggcttgtt
     1021 catgtccgcg aatttaaccc cccattaaca aaaaacgggg ggtagtgtta cttctttgtt
     1081 aactaacatt taattatttg tttcttggtt agccattctc cagaattatc catccagcgt
     1141 cgaatagtcc ggctgctaac accaaccgcc actgcaatat cttccgttga cgctcccaag
     1201 atatacatat caagcgccct acgacgtttg tcgtcgttag cagtccaccg aacagcggcg
     1261 ctttttttcc ctttgtccga ctgattttct gacgaattgg ccttcccgcc cttgcgaccg
     1321 cgtgctgcct gaatttctgg cgtgtgcgta tcagccacat actgtgcgaa agtttccggc
     1381 gtgaagttcc tgtgcgtgta tttcgcaatg ctcttgccaa tagcccgaca ttcagccagt
     1441 gaaagcggaa cgggaagcga tgcattgtac atttcgacac gctggatcac cgcttcaagc
     1501 cactgtgaga acgctggcca gccctgacga atcgccctgt aagcccattt gcgcgtcatt
     1561 tcgaacaggt ggcagtttcg ccccatcccg taatgtttat cgatgctacg acgctctgag
     1621 gcgctcaaat cgagataatc tgccagttca tcgagggtat aggcgtcctc gcgccactcc
     1681 atcacctgcc attccaggtg gaacggattt ttgcaaatca ggccgctgta gttcacatca
     1741 gcacaaagtt tctcacacag cgaacgttca accgctgcgg catatttcag cgccttaacc
     1801 gaggcatcag gcgcggttct cacggcgatg ttgagtgcgt agagcaggtg agcgtgtccg
     1861 ttcacaggat ttttaacggt gatgttcggc gcgggggcgt tccggtcgct ccagtcaatc
     1921 gcagccccct cgcggtcaac gtcaaaaacc agccagaact gcgcatgagg ctggttctgc
     1981 tggatgtacc gcgcaagaag cgcacgccct ttgccggaga tgcgaaggcc gaaagcgaga
     2041 tcatccgtgt gataggggcg gtggggtaaa ttttcttcga agtattgaag cgcggcgctc
     2101 atgtgttacg attccttcca ggttatcgac cgacctcgcc cctgtattct cgtgacaatc
     2161 ttggcggaga gacacgaatt tcaggggcgt ttgtttttca gtcgcttaca ctacccccaa
     2221 caacaaaacc tgtcgagcct tcccgcaaaa ccgatccatt taccataact cccgttgtac
     2281 gcccccttaa aacgccctca gtcgctctct ggcgcaaaaa acgcaaaaag acaaggaaac
     2341 accaggctaa accagaaaaa tgcgtcagaa tcgtttttag cgcgttgcat aactatgcac
     2401 gaaagcgatg cgcgatctgt ttcgagcgtt cagaagggcg aacgggtcaa aacagcaaac
     2461 tttctcatca gaaaacggtg aacgggacgc ggaatttttt cgcgggtcgt gaggcgttgg
     2521 acaagcgaag cgcgtcagtt tttccggctc ttgcccgtga caggtttctc cgccagttta
     2581 tcttccagtg tcacaacttt ctgatacacc gccgctgtgg cgttgtagtt cctgtcgagc
     2641 attgttttca ttccccatcc aagcacacag aacataacca gaaaagccac tgacacccca
     2701 cccagccatt tccagctata ccctttaagg gtgttgtatt cctgcacgat attgctgtga
     2761 attgtcgcaa tatccctgtt cagggcatcc gcgtttgcct tcatgtttgc gactgactct
     2821 tccagccgct gaaaatcctg gctgatgcgc tcacctatca gccctgcaac atccagcttc
     2881 tgcacctcgt ttctgacttc atccctgacc tgttttgcca caccgtcaga aatatcccga
     2941 tatccgcgaa gtgtttccct tgccacagcc agagaatcag caacagcttt ctgttgctcc
     3001 attgcggtat gttgcagatg ctccaccgat aacaggagcg tgagtaattt ttcttctgtg
     3061 ctggccatgt tcagaatccc atagaaaatc cacgtgacgg tgatttaacc cgttcaggtt
     3121 cagttcggtt ctgtctgctc actctgtctc tcatgtcaaa gccatgctcc cgcgcaacat
     3181 catgttgcag ccttctgacc agttcatgtt gcttaaccgg agtgtccagc cattccctga
     3241 tgtcataccc gaccgttcgc gcctgttcaa gatggcggga atagtccggt tcagaccgtt
     3301 tttgcatgat gtcatgacgc tgggcatcat caagccgtcc ggcagcttca aaacccagat
     3361 gcacttcggg acgtcgttca atgccctgtt ctttcagcgt ccggcagtca atgaagcccc
     3421 tttcaaagcc atgctttctc atatgttcgt tgtgcttcac ctcccagcgt tttcgcaatt
     3481 cccgcaactg ctctttttgc tgagtgagag tcaggcttcc ggaatccttt ttcgcacctc
     3541 cccgctcggg atacctggcg ttatagcgcc ggaaatactg ttccggtgta cgttcaatgc
     3601 catcattcac acgctggctc atcatgatat gcgcatgagg ctgttcgccg ccgtcaatgc
     3661 tcgctttcgg attgtgaatt gcaaaactcc aggcgtgccg ttcgccagct tcctgacgta
     3721 caaaatcctg caccagttca aggcgctgtt
//
