LOCUS       NZ_CP126777             4891 bp    DNA     circular CON 21-APR-2024
DEFINITION  Enterobacter hormaechei strain Ehh_22 plasmid pEh22_2, complete
            sequence.
ACCESSION   NZ_CP126777
VERSION     NZ_CP126777.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN35394411
            Assembly: GCF_030847985.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 4891)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss
            companion animal clinic and their genetic relationship to clinical
            human isolates
  JOURNAL   J Antimicrob Chemother 78 (12), 2950-2960 (2023)
   PUBMED   37923369
REFERENCE   2  (bases 1 to 4891)
  AUTHORS   Dona,V., Nordmann,P., Kittl,S., Schuller,S., Bouvier,M., Poirel,L.,
            Endimiani,A. and Perreten,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2023) Institute of Veterinary Bacteriology,
            University of Bern, Laenggassstrasse 122, Bern 3012, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 86x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030847985.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 14:05:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,036
            CDSs (total)                      :: 4,920
            Genes (coding)                    :: 4,823
            CDSs (with protein)               :: 4,823
            Genes (RNA)                       :: 116
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 36 of 97
            Pseudo Genes (incomplete)         :: 63 of 97
            Pseudo Genes (internal stop)      :: 14 of 97
            Pseudo Genes (multiple problems)  :: 14 of 97
            Pseudo Genes (short protein)      :: 1 of 97
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP126777.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4891
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="Ehh_22"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="pEh22_2"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-02-21"
     gene            161..1606
                     /locus_tag="QPR68_RS25160"
                     /old_locus_tag="QPR68_25140"
     CDS             161..1606
                     /locus_tag="QPR68_RS25160"
                     /old_locus_tag="QPR68_25140"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_101997250.1"
                     /translation="MFTGISVFNKNRSVNRPDNLKEFASVNGERITERKKETFNIALSM
                     KSKGEDLQDETLTKRAERSLKCSSFRYIATVNGQAQTLFTHRCKGRHCQECQRIKAYIW
                     QKKTESIFPKLEENYLNAKYLFATFTIKNPKITDLRVVLSVMNKAANRLFKMKKYKDFI
                     LGGIRSTEITRGKSGADECHPHFHFLLMVKGNYGKKYYVNQEDWGKDWGDCLAYECDRV
                     GYPYNPIDYPRGFPIVDVVRAMDKEKKIEITNKNIKNSGEAIINYVLKYSVKGSDILDH
                     KKGKNDDWFFEFDKQIKGCRMITPVGVFKKYLSEIKKDPFDYEIEKAKIEDRLGQGYQV
                     NKAIFKKGDYKLENKKDNEGYLLEALEAKAYNYQQLYLTMYSDYIKFYNDTNKEISKLE
                     DKLFTEYDNMIESKIGRLLLIQEDRKKRINNTIESLKRVGYLKEEKGLYYDEWGSLWAT
                     FEIEKTNIEIVEINDFADMFEVW"
                     /name="protein rep"
     gene            1606..1749
                     /locus_tag="QPR68_RS25165"
                     /old_locus_tag="QPR68_25145"
     CDS             1606..1749
                     /locus_tag="QPR68_RS25165"
                     /old_locus_tag="QPR68_25145"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_159106569.1"
                     /translation="MKKKQKPKKRNRNRKSKFFKLLMASVREAVEISKGNIEPARITIL
                     KK"
                     /name="hypothetical protein"
     gene            complement(1777..3075)
                     /gene="mobQ"
                     /locus_tag="QPR68_RS25170"
                     /old_locus_tag="QPR68_25150"
     CDS             complement(1777..3075)
                     /gene="mobQ"
                     /locus_tag="QPR68_RS25170"
                     /old_locus_tag="QPR68_25150"
                     /inference="COORDINATES: protein motif:HMM:NF041496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="WP_052318545.1"
                     /translation="MAIYYFDVSSVSRNSGKKSASSVAASAYQNRARYTDERTGTTYDY
                     TKKGGLYYSGILAPENAPESLTASPVALWGTVEAIEKRKDARLAKDFKISLLVELTPEQ
                     NKALILDFAQQAFVSKGMIVDLAIHDIDTQPHSHIKTTTRELTAEGFGGKVREWDKMDH
                     IMEWRELWAKVANEHLLKAGHDITISHLTLKEQMKEALEEMDKTTDLEEKIKLASKAIE
                     LNRPAMKTISKKDWGDPKFQEIRKQEQEAKKQILKKAKNFRIKNTRELREIQKELDKKF
                     RPSKIYKSISEAIRNLNNKITDSKLNNILNDKLDKLNETIKSVPDKIKHSVEKRKIKKE
                     NKERERINKEEERIFRETHKMDEFGNIYNKKEDKQYQKKNNELIKQQLASNKEKDEAER
                     QRKKLEDEANRLAEKNNISPNDFKQRKKKGPNI"
                     /name="mobQ"
     gene            3338..3640
                     /locus_tag="QPR68_RS25175"
                     /old_locus_tag="QPR68_25155"
     CDS             3338..3640
                     /locus_tag="QPR68_RS25175"
                     /old_locus_tag="QPR68_25155"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_148935522.1"
                     /translation="MSHDFYIERKKDKKKAVFNGYAEGVFYKHFHCEKYNAIWSGSNDG
                     QDVSKKGTENALRKILESEEIKNYPDPDRINEIREFYENVVLKSNDQDKFYVHFL"
                     /name="hypothetical protein"
     gene            3849..4172
                     /locus_tag="QPR68_RS25180"
                     /old_locus_tag="QPR68_25160"
     CDS             3849..4172
                     /locus_tag="QPR68_RS25180"
                     /old_locus_tag="QPR68_25160"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_047627867.1"
                     /translation="MTTTTEKKYIKRTPEQRKAYLEAQLNSVNAKLNKQKRKEANAKRR
                     ETDHLKYTFAGDILKVIGCDVREVDLSLILGAVFYATSENANPKNVELYRKTGLEILKE
                     NKK"
                     /name="hypothetical protein"
ORIGIN
        1 acggcataaa aacacggaaa aaatgggacg gtatcgactt ttagccggtg ggagaaaatt
       61 agaggggtat cgtgtaagtg cttgactggt ttgacaaaaa caaaaaaccc cgtaaagtaa
      121 gaattgctta ggttcaatac aatacggggt tcttcataat atgtttacag ggataagtgt
      181 atttaataaa aataggtctg tcaatagacc ggataatcta aaagagtttg ccagtgtaaa
      241 cggtgaacga ataacagaaa gaaaaaaaga gacctttaat attgctttgt ctatgaaaag
      301 caaaggtgaa gatctacaag acgagacact aactaaaagg gctgaaaggt ctttaaagtg
      361 ctcttctttt cgttatatcg caactgttaa cggacaggct caaaccttat ttactcaccg
      421 ttgcaaaggt cgtcattgtc aggaatgcca aagaattaag gcttatatct ggcagaaaaa
      481 aacagagtct atttttccaa aactggaaga aaattattta aatgcaaaat atctatttgc
      541 gacatttacg attaaaaacc caaaaataac agatctaagg gttgttttat cagtaatgaa
      601 taaagcagca aataggcttt ttaaaatgaa aaaatataaa gattttattc ttggcggtat
      661 ccgttcgacg gagatcacca ggggaaaatc tggggctgac gaatgccacc cccattttca
      721 ttttttgctt atggtaaaag gaaactatgg taaaaaatac tatgtaaatc aagaagattg
      781 ggggaaagat tggggggatt gcctggctta tgagtgtgat agggtagggt atccgtataa
      841 ccctatcgac tatcctcgtg ggttcccaat cgtggacgtt gtaagagcta tggataaaga
      901 aaagaaaatc gaaatcacaa ataagaatat taaaaattct ggtgaagcga ttataaatta
      961 tgttctaaaa tattccgtca aaggtagtga tattttagat cataaaaaag gaaaaaatga
     1021 cgattggttt tttgaatttg ataagcagat taaaggctgt cgaatgataa cacctgttgg
     1081 agtttttaaa aaatatctaa gtgaaattaa aaaagatccg tttgattatg aaatcgaaaa
     1141 agcaaaaata gaggatagat tgggacaagg ctatcaggtt aataaagcca tatttaaaaa
     1201 aggcgattat aaacttgaaa ataaaaaaga taatgagggt tatttattag aagcattgga
     1261 agcaaaagcc tataattacc aacaattata tttaactatg tatagcgatt atattaaatt
     1321 ctacaatgac actaacaagg aaatatctaa attagaagat aagttattta ccgaatatga
     1381 taatatgatc gagtctaaaa taggaagatt attattaatt caggaagata ggaaaaaacg
     1441 aattaataac actattgaaa gtttaaaaag ggtcggttat cttaaagaag aaaaagggct
     1501 ttattatgac gaatggggat cgctttgggc aacatttgaa attgaaaaga ccaatattga
     1561 aatagtggaa attaacgatt ttgctgatat gtttgaggtg tggtaatgaa aaagaaacag
     1621 aagcctaaaa aaagaaatcg caatagaaag agtaaatttt ttaaattatt aatggcttct
     1681 gttcgtgaag ccgttgaaat ttcgaaagga aacattgagc cagcaaggat cacaatttta
     1741 aaaaaatagt agtatagtat attgtagtat atagccctat atattcggtc ctttcttttt
     1801 tctttgctta aagtcattag gtgaaatatt atttttctca gctaatctat tagcctcgtc
     1861 ctctaatttt ttcctttgtc tttcggcttc gtccttttct ttattgctgg ctaattgttg
     1921 tttaattaac tcattatttt tcttttgata ttgcttatct tcttttttat tataaatatt
     1981 tccaaattca tccattttgt gggtttctct aaatattctc tcctcttcct tatttattct
     2041 ttccctttcc ttgttttctt tttttatttt tctcttctct acggaatgct ttattttatc
     2101 aggaactgat tttattgttt cgtttaattt atctaatttg tcatttagaa tattatttaa
     2161 ttttgagtcg gtgattttat tatttaaatt tctaattgcc tcggaaattg atttatatat
     2221 ttttgacggt ctaaattttt tatctaattc tttttgtatt tctcttaatt ctctggtgtt
     2281 tttaattcta aaatttttag ccttttttaa tatttgtttt tttgcctcct gttcctgttt
     2341 tcttatttcc tgaaatttgg gatcgcccca gtccttcttg ctgatagttt tcattgctgg
     2401 tctatttaat tcgatagcct tagaagcaag ttttattttt tcctccaggt cggttgtttt
     2461 gtccatttcc tccagtgctt ctttcatttg ttcttttaat gttaaatggc taatggttat
     2521 atcgtgtccg gcttttaata aatgttcatt agccactttt gcccataatt ccctccactc
     2581 cataatatga tccattttat cccattctct aacttttcca ccgaacccct cagccgttaa
     2641 ttctctggta gttgttttta tatggctatg tggttgggtg tctatatcgt ggatagccag
     2701 atctacaatc attccctttg agacaaaagc ctgttgtgca aagtctaaaa ttaaggcttt
     2761 gttctgttct ggggttagtt ctaccaatag ggagattttg aagtctttgg caagcctggc
     2821 atccttcctc ttctcaatgg cctctacggt accccatagt gccacaggtg aagctgtgag
     2881 actctcaggg gcattctccg gggctaaaat gccagagtag tataagcctc cttttttggt
     2941 gtaatcgtag gttgtgccgg ttcgttcgtc tgtgtacctg gctctgtttt ggtatgcgga
     3001 agcagcaaca gacgaagccg attttttgcc tgagtttcta ctcacactgg aaacatcaaa
     3061 ataatatata gccataattg taaacctcca tttttctaat tttttttggg gttggttttt
     3121 gcttttcttt tttcccgttt acgggaaaaa accctggcgt tgcgttagca atgcggagaa
     3181 gggcttcaag taatttttat tttttcgtaa actcaaaata aaaaactttc agaacggcaa
     3241 aaatgctttt ccttatttta gatataacat aaatttgact aaagtaaatt acggaggtat
     3301 atgcttaata attacaaaaa tatatatgga ggtttttatg tcgcatgatt tttatatcga
     3361 aagaaaaaaa gataaaaaga aggctgtttt taatggatat gctgagggag tattttataa
     3421 gcattttcat tgtgaaaaat ataatgctat ttggtctggt agtaatgacg gacaagatgt
     3481 atctaaaaaa ggtactgaaa atgcacttcg taaaatatta gagtcggaag aaattaagaa
     3541 ttacccagat cctgaccgta ttaatgaaat tagagaattt tatgaaaatg tagtcttgaa
     3601 atctaatgat caagataaat tctatgtaca ttttttatag gggtagatta tgatttttat
     3661 aggttttctt ttaggtctgg ggtttgtcct tataatgggt ttattgtatg aattttttaa
     3721 taattatcaa aaacttaaag gaaaaacgga cggcttagaa gctcttgttt taaggttgga
     3781 atataaatta gattatgtaa ttaatgaatg taataagagg ggttttgatt tagaggagga
     3841 aatatattat gacgacgacg actgaaaaaa aatatattaa aagaactcct gagcaaagaa
     3901 aggcatattt agaagcccag cttaatagtg taaatgcaaa actaaataag cagaaaagaa
     3961 aagaggctaa tgctaagaga agagaaacgg atcatttaaa atatactttt gcaggtgata
     4021 ttctaaaagt tatagggtgc gacgttcggg aagttgactt gtctttgatc ctcggtgccg
     4081 ttttttatgc tacaagtgaa aatgcaaacc ctaaaaatgt tgaactatat agaaaaacag
     4141 gactggaaat tttaaaagaa aataaaaaat aagtttgaca ataatataat tagaatacat
     4201 taatatataa gtcggtatgt ttatttaatt ccttgacaaa tttaatatat ataacggcaa
     4261 attgccccat ttatggggat attggagagg ctaacttagg ttagcctttc gtcctttctg
     4321 ataccgttca ccagtgccga accgtcaagc agaatgtcgg ggggtcccct ctggggttcc
     4381 gtcattgtgc ttgtacggct ccctggtcaa tacaacactt ggcaaaggtg gaaggtgaac
     4441 aaagtgagcc ttctacctga taagccgccc ttaaatggtt ttaagttgta ttaaatgaca
     4501 tttgataata caacttgccc cggtaggggt tgcctttggt tttaggggtt tggtttgagg
     4561 ttgccgaagg cgacccctcc ccttgtttag taagaaacaa atggaggcaa aacttagcct
     4621 ctaaaattcc cctgtaagcc ccgccattac tggctttaac cccctttttt tggtgttttt
     4681 taaggggggt aaatagcact ttttgctaaa gaattttaga ataaaaaata atcaattccc
     4741 cggaaatggg acaccactgc agaaacctcc cgaaaacacc cccaaaaatg ggacggaacc
     4801 tttagatcac tatccgacaa acggcagatt tgggacggaa cattttaaac accgtttttt
     4861 tggtgtgaaa aatgggacgg ttccaaccgt a
//
