LOCUS       NZ_CP123042             9030 bp    DNA     circular CON 01-JUN-2024
DEFINITION  Klebsiella pneumoniae strain KP160802 plasmid pKP160802-2, complete
            sequence.
ACCESSION   NZ_CP123042
VERSION     NZ_CP123042.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN34174741
            Assembly: GCF_029854575.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9030)
  AUTHORS   Chen,J., Li,X., Chen,C. and Huang,L.
  TITLE     Klebsiella pneumoniae strain KP160802
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9030)
  AUTHORS   Chen,J., Li,X., Chen,C. and Huang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-APR-2023) Zhuhai hospital, Jinan University, 79
            Kangning Road, Zhuhai, Guangdong 519000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. 0.13-r308; Canu v. 1.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.07x
            Sequencing Technology             :: Illumina NovaSeq; PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029854575.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:30:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,381
            CDSs (total)                      :: 5,258
            Genes (coding)                    :: 5,154
            CDSs (with protein)               :: 5,154
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 48 of 104
            Pseudo Genes (incomplete)         :: 61 of 104
            Pseudo Genes (internal stop)      :: 16 of 104
            Pseudo Genes (multiple problems)  :: 16 of 104
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP123042.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9030
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP160802"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKP160802-2"
                     /geo_loc_name="China: Guangzhou"
                     /lat_lon="23.19 N 113.33 E"
                     /collection_date="2022"
                     /collected_by="Jing Chen"
     gene            441..1559
                     /locus_tag="QDE57_RS26825"
                     /old_locus_tag="QDE57_26825"
     CDS             441..1559
                     /locus_tag="QDE57_RS26825"
                     /old_locus_tag="QDE57_26825"
                     /inference="COORDINATES: protein motif:HMM:NF014691.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="WP_151085616.1"
                     /translation="MKRTMHNIGDTDKENKGEMNISLYNFKKAEGVQEKIIHIKKTQFK
                     NKLVNFFWNTSKNEVLKGMGKVSSISDFHSTAHALSYGSDTSEIKNRTEIQLGDSVFYY
                     KKLSVDNESFVFGYVTGIFRKNNIESIEITRTSLDKTINRSQIKLILEKNTPIFLLSNG
                     YNDRYEKLAPTNNKLKIMYKYQLDSLEFVLGNVRLLHLIKNRYSNRQIPLGELAFKEIH
                     KSMFGDIHHWAGEYRNHEVIVGDRGRETVHQTEISKCMKTAFQKTHKNRLSSINNIDSL
                     SNMLTILHKDLAWIHPFEDGNGRAIRFYLLILSLSLGFKMDLKVFIGDKKRKSFYHYAV
                     RKAIYDNNNKYLHRIIKNSLTMISHNTNSQKN"
                     /name="Fic family protein"
     gene            2296..2505
                     /locus_tag="QDE57_RS26830"
                     /old_locus_tag="QDE57_26830"
     CDS             2296..2505
                     /locus_tag="QDE57_RS26830"
                     /old_locus_tag="QDE57_26830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgH/BhsA/McbA-like domain containing protein"
                     /protein_id="WP_073511423.1"
                     /translation="MKSIKTFVAVTALSMMSFGAFAQSVSATASTLDRAEAKIAAQAAE
                     QGASYKITSAQFNNRVHMTAELTK"
                     /name="YdgH/BhsA/McbA-like domain containing protein"
     gene            complement(3348..3749)
                     /locus_tag="QDE57_RS26835"
                     /old_locus_tag="QDE57_26835"
     CDS             complement(3348..3749)
                     /locus_tag="QDE57_RS26835"
                     /old_locus_tag="QDE57_26835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_280103469.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSVQVSEQRDTASADQSEQVIRHLRQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPVPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(3749..3940)
                     /locus_tag="QDE57_RS26840"
                     /old_locus_tag="QDE57_26840"
     CDS             complement(3749..3940)
                     /locus_tag="QDE57_RS26840"
                     /old_locus_tag="QDE57_26840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_258336618.1"
                     /translation="MTKQQKTALNMAKFIQHQSLLLLEKLNELDLDAEAGLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            4956..6074
                     /locus_tag="QDE57_RS26845"
                     /old_locus_tag="QDE57_26845"
     CDS             4956..6074
                     /locus_tag="QDE57_RS26845"
                     /old_locus_tag="QDE57_26845"
                     /inference="COORDINATES: protein motif:HMM:NF014691.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="WP_151085616.1"
                     /translation="MKRTMHNIGDTDKENKGEMNISLYNFKKAEGVQEKIIHIKKTQFK
                     NKLVNFFWNTSKNEVLKGMGKVSSISDFHSTAHALSYGSDTSEIKNRTEIQLGDSVFYY
                     KKLSVDNESFVFGYVTGIFRKNNIESIEITRTSLDKTINRSQIKLILEKNTPIFLLSNG
                     YNDRYEKLAPTNNKLKIMYKYQLDSLEFVLGNVRLLHLIKNRYSNRQIPLGELAFKEIH
                     KSMFGDIHHWAGEYRNHEVIVGDRGRETVHQTEISKCMKTAFQKTHKNRLSSINNIDSL
                     SNMLTILHKDLAWIHPFEDGNGRAIRFYLLILSLSLGFKMDLKVFIGDKKRKSFYHYAV
                     RKAIYDNNNKYLHRIIKNSLTMISHNTNSQKN"
                     /name="Fic family protein"
     gene            6811..7020
                     /locus_tag="QDE57_RS26850"
                     /old_locus_tag="QDE57_26850"
     CDS             6811..7020
                     /locus_tag="QDE57_RS26850"
                     /old_locus_tag="QDE57_26850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgH/BhsA/McbA-like domain containing protein"
                     /protein_id="WP_073511423.1"
                     /translation="MKSIKTFVAVTALSMMSFGAFAQSVSATASTLDRAEAKIAAQAAE
                     QGASYKITSAQFNNRVHMTAELTK"
                     /name="YdgH/BhsA/McbA-like domain containing protein"
     gene            complement(7863..8264)
                     /locus_tag="QDE57_RS26855"
                     /old_locus_tag="QDE57_26855"
     CDS             complement(7863..8264)
                     /locus_tag="QDE57_RS26855"
                     /old_locus_tag="QDE57_26855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_280103469.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSVQVSEQRDTASADQSEQVIRHLRQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPVPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(8264..8455)
                     /locus_tag="QDE57_RS26860"
                     /old_locus_tag="QDE57_26860"
     CDS             complement(8264..8455)
                     /locus_tag="QDE57_RS26860"
                     /old_locus_tag="QDE57_26860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_258336618.1"
                     /translation="MTKQQKTALNMAKFIQHQSLLLLEKLNELDLDAEAGLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     Typing          2..127
                     /name="rep_cluster_2374"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.26"
                     /coverage="98.0"
                     /evalue="1.26e-28"
     Typing          3989..4461
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.199"
                     /coverage="92.0"
                     /evalue="6e-157"
     Typing          8504..8976
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.199"
                     /coverage="92.0"
                     /evalue="6e-157"
ORIGIN
        1 tataactaat ttggtttctg tgctctgcga aagccagtta ccacggttag ataatctgcc
       61 aggattaact aaccttcgaa aaaccacctg ccagggtggt tttttcgttt acaggccaag
      121 agactacgac gccacggaaa ggatcacaag taaatctgtt agatctcaca cagacgttaa
      181 gcccatccac ccactacaca tcatcaccaa tgacttaaag actcaacata accacatgat
      241 ttaattaaag atatagatga atccgtaata tgaaaaagcg tgttctcatg ctccatgagc
      301 tcctcctaca cttatttttg atgagttatt aagctatgcc gttgcatggc aaaaagagat
      361 gctattgtga acaacctttt ttataagata ttatctataa gattacatgg cacttcagat
      421 taataccggc gattttaatt atgaaaagaa caatgcataa cattggtgat acagacaaag
      481 aaaataaagg tgaaatgaac atatctttat acaactttaa aaaggcagaa ggtgttcaag
      541 aaaaaataat tcacataaaa aaaacgcaat tcaagaataa attggttaat ttcttttgga
      601 acactagtaa aaatgaagtt ctaaaaggca tgggtaaagt tagtagcata agtgactttc
      661 acagtacagc tcatgcactt tcctacggta gtgataccag tgaaataaaa aacagaacag
      721 agatacagct tggagactct gttttttact acaaaaaatt gagtgtggat aatgaatcat
      781 ttgtctttgg gtatgtcact ggaatattca gaaaaaacaa cattgagtct attgaaataa
      841 caagaacatc tcttgataag acaataaaca gaagtcaaat taaattgatt ttagaaaaaa
      901 acacaccaat attcttatta tcaaatggat ataatgatcg atatgaaaaa ctagccccaa
      961 caaacaacaa gctaaaaata atgtataaat atcaactaga tagccttgag tttgttttgg
     1021 ggaatgtgcg gctattgcat ttaattaaga atagatacag taacagacaa ataccattgg
     1081 gtgagttagc atttaaggaa atacataaat caatgtttgg ggacattcat cattgggccg
     1141 gggaataccg taatcatgaa gttatagttg gtgatagggg cagggagacg gtgcaccaaa
     1201 cagagataag taaatgcatg aagacagcct ttcaaaaaac acataaaaac aggttaagca
     1261 gcataaataa cattgactcc ttatccaaca tgctcacaat cctgcataaa gatttggcat
     1321 ggattcatcc attcgaagat ggaaatggga gagcgataag attttattta ttaatcctat
     1381 cgctatctct cggatttaaa atggacttaa aagtgttcat tggagacaaa aagcgtaaat
     1441 cattttacca ctatgcggta agaaaggcga tttacgataa taataataaa tatctacata
     1501 ggataataaa aaactctcta actatgatat cccataatac gaattctcaa aagaactaat
     1561 aagtctttta gactcacttt cattcatgtt gattacatcg ccttccagat acaatgatga
     1621 cagcagagag tcatgaatga aaccaatcaa ctcaccaact tccatagaga atgattgatc
     1681 atcatttctc aactcgaagg ctactgattc caaacaatgt gacatagtta tccgcctagg
     1741 gttataaaaa aagcataata atcaacgact taaagcacta agccactgac gtaccggggc
     1801 gctgtagtga actacagcgc cccggtacgt cagtggcctt acattatcat gaatttcgca
     1861 aaaagtcaat agctaaaata tatcatcata acgagagggt tgtaatctca ttattgctac
     1921 taaacaaata gggcatagcc catcatgcaa ttcatatagc aaagaaaatt aaattttaac
     1981 aaatagttag catgattact caaatgcatc acgccataaa aaatcagcaa ttatcagcca
     2041 ataagtacgc atatataaat ggctgctaac tctctaaaga gggtcgacaa agttaccccc
     2101 cccccctcga ggctattcat cctgccccta aatcagagtc tcacatctgg ttttggcgtg
     2161 ctcaattttt gttctatttt tttgaataat atccgcaaat tgtttcgatt ttaatcagct
     2221 catggtcgcc ctattattta tcacatcagg gcaacaacgc cccatacaga acaaaatgac
     2281 ttaaggaata cgaccatgaa atcaatcaaa actttcgttg cagttaccgc tctatccatg
     2341 atgtctttcg gtgcctttgc tcagagcgtc agcgctaccg cctccaccct ggatcgtgct
     2401 gaagcaaaaa ttgccgcaca ggccgctgaa caaggtgcgt catacaaaat caccagcgct
     2461 cagttcaata accgtgtcca catgacggct gaactgacca aataagatgg tcgcagaggg
     2521 agctgccgaa caggtcgccg ggaggcggcc cgtttcgtcc cttagcagga aaaccctcag
     2581 gccccttcgg gggctttttt gcacctgcca tttaacataa aggcatgatt gtacgcaccg
     2641 ctaaaacggc ctcaggacgt ttctgacggg aaaccggtaa aacaggcaac aaaccacccg
     2701 aaaacccgcc agaaacgcgc aggctctgtt tttacggcat gcatgagtat gcacgcaagt
     2761 gcatagcgcg aaaattcacg ccattcagcc agggtaagtc ctgtttccgg cgttcttccc
     2821 atccgaaaac ggtgaacggg gacgcaattt attgcgtggc cgtgaatcgt tgccggcgca
     2881 gcaggaaaac cggttttcag cacgatcagg aatagggttc gtcgacggcc ggcaatcacg
     2941 ttatggcaag tcgccggacg actcaccaca cgattcaccg gcgattcgac tcgtgacttg
     3001 actctagagt cgtcaaggtc aaaaaaacac caaagtgacg attcgactct agagtcaagt
     3061 cgtcataagt tactgatagt gtggagtgag tcgtcgatga ctctatgacg agtcgtcggc
     3121 aagtcgtaca cgaatcaccg acgacttgga ttgaccttac agaaggtaat actgcgtaat
     3181 ttaataacaa ccaactaact gatattaatg agttatctgc aaaaatttaa ttttgcgtgg
     3241 ggtgtgggta tttttagtgg tgaggagcgt tcagagatct gccgattttt gggaaggttc
     3301 aggaactccc cgggatggcc ggagaggaaa actgaagcat gacggggtca ggattttttc
     3361 cagaatttcc accatggcac cggggattca gttaattttg cctggtgatt ttcaagaagg
     3421 agcatggcct gtttcaggct gtcaatgtgc gaatccttgg acaaaagtaa ggtgttcagg
     3481 tgttcaatct cctgtctcag atgacgaatc acctgttcac tctggtcagc agaggctgta
     3541 tcacgctgtt cagagacctg tacagaatgg tgttcaccct tcggttgctc aaagggacca
     3601 aagacacgta aaagctctga agtatctacc atttttgcat tacgctcacc gctacaggtg
     3661 gacaggtcac ctgctttaat taacctgtgc agtgttgttc tactcttacc cgtcagtcgg
     3721 gcagcctcac taatagacac tctggccatc agttaccatc ctgtaatgca tccagtctcg
     3781 aggacagtgt acggaaaaga tgctccgcat cgtcgtggag tttctcacaa aggccggcct
     3841 cagcatcaag atcaagctcg ttaagcttct ccagcaggag cagagactga tgctggatga
     3901 atttagccat gttcagcgct gttttctgtt gtttagtcat aagaagcctc agagcgtcag
     3961 tgctcagtgt agaaccagtc tcttttccgc ttcctcgctc actcagtcgc tacgctccgg
     4021 tcgttcggct gcggcgagcg gcaggagcat atacacaaaa gagtaggtaa ccagaggtat
     4081 aagggagaaa aggaaaagcc gccgcgcggc tgtttttcca taggcttcgc ccccctgaca
     4141 agtatcacag aatctgacac tcaaatcagt ggtggcgaaa cccgacagga ctataaagat
     4201 accaggcgtt tccccctgat ggctccctcg tgcgctctcc tgttcctgcc tttcggttta
     4261 ccggtgtcat tccgctgtta tggccgcgtt tatctcattc cacgcctgac actcagctcc
     4321 gggtaggcag ttcgctccaa gctggactgt gtgcacgaac cccccgttca gtccgactgc
     4381 tgcgccttat ccggtaacta tcatcttgag tccaacccgg aaagacacga caaaacgcca
     4441 ctggcagcag ccactggtaa caggttcgca gaacaaagaa gtcttgaagt gtggggctaa
     4501 ctacagctac actgctataa ctaatttggt ttctgtgctc tgcgaaagcc agttaccacg
     4561 gttagataat ctgccaggat taactaacct tcgaaaaacc acctgccagg gtggtttttt
     4621 cgtttacagg ccaagagact acgacgccac ggaaaggatc acaagtaaat ctgttagatc
     4681 tcacacagac gttaagccca tccacccact acacatcatc accaatgact taaagactca
     4741 acataaccac atgatttaat taaagatata gatgaatccg taatatgaaa aagcgtgttc
     4801 tcatgctcca tgagctcctc ctacacttat ttttgatgag ttattaagct atgccgttgc
     4861 atggcaaaaa gagatgctat tgtgaacaac cttttttata agatattatc tataagatta
     4921 catggcactt cagattaata ccggcgattt taattatgaa aagaacaatg cataacattg
     4981 gtgatacaga caaagaaaat aaaggtgaaa tgaacatatc tttatacaac tttaaaaagg
     5041 cagaaggtgt tcaagaaaaa ataattcaca taaaaaaaac gcaattcaag aataaattgg
     5101 ttaatttctt ttggaacact agtaaaaatg aagttctaaa aggcatgggt aaagttagta
     5161 gcataagtga ctttcacagt acagctcatg cactttccta cggtagtgat accagtgaaa
     5221 taaaaaacag aacagagata cagcttggag actctgtttt ttactacaaa aaattgagtg
     5281 tggataatga atcatttgtc tttgggtatg tcactggaat attcagaaaa aacaacattg
     5341 agtctattga aataacaaga acatctcttg ataagacaat aaacagaagt caaattaaat
     5401 tgattttaga aaaaaacaca ccaatattct tattatcaaa tggatataat gatcgatatg
     5461 aaaaactagc cccaacaaac aacaagctaa aaataatgta taaatatcaa ctagatagcc
     5521 ttgagtttgt tttggggaat gtgcggctat tgcatttaat taagaataga tacagtaaca
     5581 gacaaatacc attgggtgag ttagcattta aggaaataca taaatcaatg tttggggaca
     5641 ttcatcattg ggccggggaa taccgtaatc atgaagttat agttggtgat aggggcaggg
     5701 agacggtgca ccaaacagag ataagtaaat gcatgaagac agcctttcaa aaaacacata
     5761 aaaacaggtt aagcagcata aataacattg actccttatc caacatgctc acaatcctgc
     5821 ataaagattt ggcatggatt catccattcg aagatggaaa tgggagagcg ataagatttt
     5881 atttattaat cctatcgcta tctctcggat ttaaaatgga cttaaaagtg ttcattggag
     5941 acaaaaagcg taaatcattt taccactatg cggtaagaaa ggcgatttac gataataata
     6001 ataaatatct acataggata ataaaaaact ctctaactat gatatcccat aatacgaatt
     6061 ctcaaaagaa ctaataagtc ttttagactc actttcattc atgttgatta catcgccttc
     6121 cagatacaat gatgacagca gagagtcatg aatgaaacca atcaactcac caacttccat
     6181 agagaatgat tgatcatcat ttctcaactc gaaggctact gattccaaac aatgtgacat
     6241 agttatccgc ctagggttat aaaaaaagca taataatcaa cgacttaaag cactaagcca
     6301 ctgacgtacc ggggcgctgt agtgaactac agcgccccgg tacgtcagtg gccttacatt
     6361 atcatgaatt tcgcaaaaag tcaatagcta aaatatatca tcataacgag agggttgtaa
     6421 tctcattatt gctactaaac aaatagggca tagcccatca tgcaattcat atagcaaaga
     6481 aaattaaatt ttaacaaata gttagcatga ttactcaaat gcatcacgcc ataaaaaatc
     6541 agcaattatc agccaataag tacgcatata taaatggctg ctaactctct aaagagggtc
     6601 gacaaagtta cccccccccc ctcgaggcta ttcatcctgc ccctaaatca gagtctcaca
     6661 tctggttttg gcgtgctcaa tttttgttct atttttttga ataatatccg caaattgttt
     6721 cgattttaat cagctcatgg tcgccctatt atttatcaca tcagggcaac aacgccccat
     6781 acagaacaaa atgacttaag gaatacgacc atgaaatcaa tcaaaacttt cgttgcagtt
     6841 accgctctat ccatgatgtc tttcggtgcc tttgctcaga gcgtcagcgc taccgcctcc
     6901 accctggatc gtgctgaagc aaaaattgcc gcacaggccg ctgaacaagg tgcgtcatac
     6961 aaaatcacca gcgctcagtt caataaccgt gtccacatga cggctgaact gaccaaataa
     7021 gatggtcgca gagggagctg ccgaacaggt cgccgggagg cggcccgttt cgtcccttag
     7081 caggaaaacc ctcaggcccc ttcgggggct tttttgcacc tgccatttaa cataaaggca
     7141 tgattgtacg caccgctaaa acggcctcag gacgtttctg acgggaaacc ggtaaaacag
     7201 gcaacaaacc acccgaaaac ccgccagaaa cgcgcaggct ctgtttttac ggcatgcatg
     7261 agtatgcacg caagtgcata gcgcgaaaat tcacgccatt cagccagggt aagtcctgtt
     7321 tccggcgttc ttcccatccg aaaacggtga acggggacgc aatttattgc gtggccgtga
     7381 atcgttgccg gcgcagcagg aaaaccggtt ttcagcacga tcaggaatag ggttcgtcga
     7441 cggccggcaa tcacgttatg gcaagtcgcc ggacgactca ccacacgatt caccggcgat
     7501 tcgactcgtg acttgactct agagtcgtca aggtcaaaaa aacaccaaag tgacgattcg
     7561 actctagagt caagtcgtca taagttactg atagtgtgga gtgagtcgtc gatgactcta
     7621 tgacgagtcg tcggcaagtc gtacacgaat caccgacgac ttggattgac cttacagaag
     7681 gtaatactgc gtaatttaat aacaaccaac taactgatat taatgagtta tctgcaaaaa
     7741 tttaattttg cgtggggtgt gggtattttt agtggtgagg agcgttcaga gatctgccga
     7801 tttttgggaa ggttcaggaa ctccccggga tggccggaga ggaaaactga agcatgacgg
     7861 ggtcaggatt ttttccagaa tttccaccat ggcaccgggg attcagttaa ttttgcctgg
     7921 tgattttcaa gaaggagcat ggcctgtttc aggctgtcaa tgtgcgaatc cttggacaaa
     7981 agtaaggtgt tcaggtgttc aatctcctgt ctcagatgac gaatcacctg ttcactctgg
     8041 tcagcagagg ctgtatcacg ctgttcagag acctgtacag aatggtgttc acccttcggt
     8101 tgctcaaagg gaccaaagac acgtaaaagc tctgaagtat ctaccatttt tgcattacgc
     8161 tcaccgctac aggtggacag gtcacctgct ttaattaacc tgtgcagtgt tgttctactc
     8221 ttacccgtca gtcgggcagc ctcactaata gacactctgg ccatcagtta ccatcctgta
     8281 atgcatccag tctcgaggac agtgtacgga aaagatgctc cgcatcgtcg tggagtttct
     8341 cacaaaggcc ggcctcagca tcaagatcaa gctcgttaag cttctccagc aggagcagag
     8401 actgatgctg gatgaattta gccatgttca gcgctgtttt ctgttgttta gtcataagaa
     8461 gcctcagagc gtcagtgctc agtgtagaac cagtctcttt tccgcttcct cgctcactca
     8521 gtcgctacgc tccggtcgtt cggctgcggc gagcggcagg agcatataca caaaagagta
     8581 ggtaaccaga ggtataaggg agaaaaggaa aagccgccgc gcggctgttt ttccataggc
     8641 ttcgcccccc tgacaagtat cacagaatct gacactcaaa tcagtggtgg cgaaacccga
     8701 caggactata aagataccag gcgtttcccc ctgatggctc cctcgtgcgc tctcctgttc
     8761 ctgcctttcg gtttaccggt gtcattccgc tgttatggcc gcgtttatct cattccacgc
     8821 ctgacactca gctccgggta ggcagttcgc tccaagctgg actgtgtgca cgaacccccc
     8881 gttcagtccg actgctgcgc cttatccggt aactatcatc ttgagtccaa cccggaaaga
     8941 cacgacaaaa cgccactggc agcagccact ggtaacaggt tcgcagaaca aagaagtctt
     9001 gaagtgtggg gctaactaca gctacactgc
//
