LOCUS       NZ_CP122934            24405 bp    DNA     circular CON 08-JUN-2024
DEFINITION  Escherichia coli strain ETEC1702 plasmid unnamed5, complete
            sequence.
ACCESSION   NZ_CP122934
VERSION     NZ_CP122934.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN32549585
            Assembly: GCF_030012765.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24405)
  AUTHORS   Vereecke,N., Van Hoorde,S., Sperling,D., Theuns,S., Devriendt,B. and
            Cox,E.
  TITLE     Virotyping and genetic antimicrobial susceptibility testing of
            porcine ETEC/STEC strains and associated plasmid types
  JOURNAL   Front Microbiol 14, 1139312 (2023)
   PUBMED   37143544
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24405)
  AUTHORS   Vereecke,N., Van hoorde,S., Sperling,D., Theuns,S., Devriendt,B. and
            Cox,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-APR-2023) Department of Pathobiology, Pharmacology and
            Zoological Medicine, Universiteit Gent, Salisburylaan 133, Merelbeke
            9820, Belgium
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Trycycler; minimap2; medaka v. v0.5.3; v2.20;
            v1.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 131x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030012765.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:03:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,103
            CDSs (total)                      :: 4,982
            Genes (coding)                    :: 4,631
            CDSs (with protein)               :: 4,631
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 351
            CDSs (without protein)            :: 351
            Pseudo Genes (ambiguous residues) :: 0 of 351
            Pseudo Genes (frameshifted)       :: 166 of 351
            Pseudo Genes (incomplete)         :: 195 of 351
            Pseudo Genes (internal stop)      :: 51 of 351
            Pseudo Genes (multiple problems)  :: 54 of 351
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP122934.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24405
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="ETEC1702"
                     /isolation_source="feces"
                     /host="Sus scrofa"
                     /db_xref="taxon:562"
                     /plasmid="unnamed5"
                     /geo_loc_name="Belgium"
                     /collection_date="2012"
                     /collected_by="IMM_DI04"
     gene            1..>306
                     /locus_tag="QDX05_RS25025"
                     /old_locus_tag="QDX05_25020"
                     /pseudo=""
     CDS             1..>306
                     /locus_tag="QDX05_RS25025"
                     /old_locus_tag="QDX05_25020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            485..748
                     /locus_tag="QDX05_RS25030"
                     /old_locus_tag="QDX05_25025"
     CDS             485..748
                     /locus_tag="QDX05_RS25030"
                     /old_locus_tag="QDX05_25025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="WP_001312455.1"
                     /translation="MTIKILVVSNDGHEKLIDLSPDNDLAKITKSLRTAENRMVCVIQD
                     NNRILRWDRSYASRAKNHWRKVAPDRFEILGTVEHIHYVGKC"
                     /name="PilI type IV pilus biogenesis protein"
     gene            complement(780..1013)
                     /locus_tag="QDX05_RS25035"
                     /old_locus_tag="QDX05_25030"
     CDS             complement(780..1013)
                     /locus_tag="QDX05_RS25035"
                     /old_locus_tag="QDX05_25030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000024515.1"
                     /translation="MANVPPKPRNTKGEPPSLEDTQHGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(1053..1700)
                     /locus_tag="QDX05_RS25040"
                     /old_locus_tag="QDX05_25035"
     CDS             complement(1053..1700)
                     /locus_tag="QDX05_RS25040"
                     /old_locus_tag="QDX05_25035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000214917.1"
                     /translation="MTVAIALVNGKGGVKKSSMSRAIATEYTKADWKVLGLDMDVDQGS
                     FLDWGQRRLRYKVEPPVTIQGCGTVSQAKKHIESGIWDLVVIDSAAYATKSLLSLAEIV
                     DLLVLPSGFSVDDLRTTVTTVNALRNKGHSTNKMAVVFVGVSESESEYRTALEYLKPCG
                     VQVINGAIPFMTSFSQAQDKGLALTESPFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     gene            2066..2416
                     /locus_tag="QDX05_RS25045"
                     /old_locus_tag="QDX05_25040"
     CDS             2066..2416
                     /locus_tag="QDX05_RS25045"
                     /old_locus_tag="QDX05_25040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269926.1"
                     /translation="MWTVYFGRLFDEWFEEQELALKRKVLAELKHLEEFGPSLSRPHAD
                     TVKGSRHKNMKELRIQYEGHPIRAFFAFDPIRQAIILCAGDKSNDKKFYDRMIRIADEE
                     FSTHLAELEGKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            2413..2712
                     /locus_tag="QDX05_RS25050"
                     /old_locus_tag="QDX05_25045"
     CDS             2413..2712
                     /locus_tag="QDX05_RS25050"
                     /old_locus_tag="QDX05_25045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001259443.1"
                     /translation="MRTLEEVIAAQSPESQAIIKAMADEMILETGLQMMREELQLSQKQ
                     VADAMGISQPAVTQLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFNI"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(2743..2988)
                     /locus_tag="QDX05_RS25055"
                     /old_locus_tag="QDX05_25050"
     CDS             complement(2743..2988)
                     /locus_tag="QDX05_RS25055"
                     /old_locus_tag="QDX05_25050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001193619.1"
                     /translation="MQTKPTPADVKEARISAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTITAEPTTV"
                     /name="hypothetical protein"
     gene            complement(2978..3235)
                     /locus_tag="QDX05_RS25060"
                     /old_locus_tag="QDX05_25055"
     CDS             complement(2978..3235)
                     /locus_tag="QDX05_RS25060"
                     /old_locus_tag="QDX05_25055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000845367.1"
                     /translation="MKTDNVFFKSKGSYSYVVTVDMDNQMYMVRKYVKTYVKSCDKEQV
                     KGKKTVKKLVLDTNLTLPELLDLDNGILADLFTRGNNNAN"
                     /name="hypothetical protein"
     gene            complement(3271..3813)
                     /locus_tag="QDX05_RS25065"
                     /old_locus_tag="QDX05_25060"
     CDS             complement(3271..3813)
                     /locus_tag="QDX05_RS25065"
                     /old_locus_tag="QDX05_25060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000206647.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTEIRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANALDEIELL
                     REHESALQEKQDKVRIIKGMLSQLLSISPWYGALTGFNADNGLAGKILQNGDDYEMVIR
                     GLNVDQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            complement(3941..4474)
                     /locus_tag="QDX05_RS25070"
                     /old_locus_tag="QDX05_25065"
     CDS             complement(3941..4474)
                     /locus_tag="QDX05_RS25070"
                     /old_locus_tag="QDX05_25065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025389.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKNAFKKAALKYHPDRNPVGAEMMK
                     AVNSAFDFLMANLDKINQYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="J domain-containing protein"
     gene            complement(4845..5144)
                     /locus_tag="QDX05_RS25075"
                     /old_locus_tag="QDX05_25070"
     CDS             complement(4845..5144)
                     /locus_tag="QDX05_RS25075"
                     /old_locus_tag="QDX05_25070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000113288.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGEKYIVVFTDNNK
                     IRDYKNGVIEELGEITQEDIELIEYYAKKYEKYFDDLKIGEEPLNLKEYIECMQ"
                     /name="hypothetical protein"
     gene            complement(5218..5490)
                     /locus_tag="QDX05_RS25080"
                     /old_locus_tag="QDX05_25075"
     CDS             complement(5218..5490)
                     /locus_tag="QDX05_RS25080"
                     /old_locus_tag="QDX05_25075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001272119.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTNQEGT
                     EFLSTLQEITTELDALIDAVESHSPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            complement(6441..7106)
                     /locus_tag="QDX05_RS25085"
                     /old_locus_tag="QDX05_25080"
     CDS             complement(6441..7106)
                     /locus_tag="QDX05_RS25085"
                     /old_locus_tag="QDX05_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371526.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_001350943.1"
                     /translation="MAKQSPCYNVVSRKRRRFLNRWIKSLTTVAGRIKIKNELRRRIRH
                     NRYWVNEANKFGIEALCELMLAILDDLDLRSWETRHNLETLAERAGLVTRSDAGHKSIS
                     RASRGCDRLVWLNAIITEKAPFNPYDARCACKHIEVTEDFFAILGIPLKLVYRERARLL
                     KADPDEVIYSGDARLIAIRVQNWTRKAAAGLARMKAKRDAARQRKKEYYAHSPTPIPA"
                     /name="RepA family replication protein"
     gene            complement(7722..8087)
                     /locus_tag="QDX05_RS25090"
                     /old_locus_tag="QDX05_25085"
     CDS             complement(7722..8087)
                     /locus_tag="QDX05_RS25090"
                     /old_locus_tag="QDX05_25085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000248966.1"
                     /translation="MVPKRLKEARMEAGLSQEKLSQLLGVAEGINTRSRFSSYEVGRTE
                     PPFKLVKKIAELLDYPENYFYTEDDDFAKAVLDFHRKRTSPELNPNYDSEVEARRMASK
                     LDNVKKIVAQLNEYLKE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            8342..8791
                     /locus_tag="QDX05_RS25095"
                     /old_locus_tag="QDX05_25090"
     CDS             8342..8791
                     /locus_tag="QDX05_RS25095"
                     /old_locus_tag="QDX05_25090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998906.1"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_000995159.1"
                     /translation="MNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIKITPRKDCNAV
                     RKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKVVIAIKCAKIL
                     ALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            8868..9080
                     /locus_tag="QDX05_RS25100"
                     /old_locus_tag="QDX05_25095"
     CDS             8868..9080
                     /locus_tag="QDX05_RS25100"
                     /old_locus_tag="QDX05_25095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001133545.1"
                     /translation="MPNPIGQAKSTAVIYIGKKRYETLAKHARDISYVAEVNIRPSAFL
                     QYMIDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            9081..9287
                     /locus_tag="QDX05_RS25105"
                     /old_locus_tag="QDX05_25100"
     CDS             9081..9287
                     /locus_tag="QDX05_RS25105"
                     /old_locus_tag="QDX05_25100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125884.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNGKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     gene            9303..10007
                     /locus_tag="QDX05_RS25110"
                     /old_locus_tag="QDX05_25105"
     CDS             9303..10007
                     /locus_tag="QDX05_RS25110"
                     /old_locus_tag="QDX05_25105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000953548.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTRDDIATQSAILNATPVEAPTRPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            10011..10307
                     /locus_tag="QDX05_RS25115"
                     /old_locus_tag="QDX05_25110"
     CDS             10011..10307
                     /locus_tag="QDX05_RS25115"
                     /old_locus_tag="QDX05_25110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000608756.1"
                     /translation="MINKLKAICSRASAYILAPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            10320..13064
                     /locus_tag="QDX05_RS25120"
                     /old_locus_tag="QDX05_25115"
     CDS             10320..13064
                     /locus_tag="QDX05_RS25120"
                     /old_locus_tag="QDX05_25115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_001096401.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLFLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLLTHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLIADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDARTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            13079..13783
                     /locus_tag="QDX05_RS25125"
                     /old_locus_tag="QDX05_25120"
     CDS             13079..13783
                     /locus_tag="QDX05_RS25125"
                     /old_locus_tag="QDX05_25120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000819778.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLADERRKKWN
                     QQQLNAPEIMFN"
                     /name="type IV secretion system protein"
     gene            13795..14022
                     /locus_tag="QDX05_RS25130"
                     /old_locus_tag="QDX05_25125"
     CDS             13795..14022
                     /locus_tag="QDX05_RS25130"
                     /old_locus_tag="QDX05_25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000720509.1"
                     /translation="MKKIILFTIISGLMALTSGCKEEAKTTKWYREHPDELKVVYAECQ
                     KTGSASENCKHANEAHWQIQQLNAPEISFN"
                     /name="EexN family lipoprotein"
     gene            14032..15102
                     /locus_tag="QDX05_RS25135"
                     /old_locus_tag="QDX05_25130"
     CDS             14032..15102
                     /locus_tag="QDX05_RS25135"
                     /old_locus_tag="QDX05_25130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_024187435.1"
                     /translation="MMAGIFSSVEKNIIGGITDATNGLMMSYSSMMMGLAATSATIYIM
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGIKEGFSSSTSI
                     WQLLDTLWNSARVLGKTLHDLDNSEFIKEEGTIAELFVWGGVFVLMIITAFVSMIAEIM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAAILTIMFSALALRIVIGFLTSRMSEA
                     VTQASKANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     SAPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            15152..15295
                     /locus_tag="QDX05_RS25140"
                     /old_locus_tag="QDX05_25135"
     CDS             15152..15295
                     /locus_tag="QDX05_RS25140"
                     /old_locus_tag="QDX05_25135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000825480.1"
                     /translation="MKRLIALALLCVLSGCAQKSKSLPHAFSGQGSPVNTPQIIAELTT
                     HD"
                     /name="hypothetical protein"
     gene            15288..15971
                     /locus_tag="QDX05_RS25145"
                     /old_locus_tag="QDX05_25140"
     CDS             15288..15971
                     /locus_tag="QDX05_RS25145"
                     /old_locus_tag="QDX05_25140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000139290.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLITILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            15971..16876
                     /gene="virB9"
                     /locus_tag="QDX05_RS25150"
                     /old_locus_tag="QDX05_25145"
     CDS             15971..16876
                     /gene="virB9"
                     /locus_tag="QDX05_RS25150"
                     /old_locus_tag="QDX05_25145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001230135.1"
                     /translation="MRKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQTQIQKALRTAQTPRNWDYTKYPGKDSYNIEPDFAYDDGRFTFLGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQEITPRLVLRSGDAVVGLKNNGFGKVH
                     AADNSTVSDKVERVEKTDNT"
                     /name="virB9"
     gene            16918..18183
                     /gene="virB10"
                     /locus_tag="QDX05_RS25155"
                     /old_locus_tag="QDX05_25150"
     CDS             16918..18183
                     /gene="virB10"
                     /locus_tag="QDX05_RS25155"
                     /old_locus_tag="QDX05_25150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000129037.1"
                     /translation="MTDENKSPSTEEEKPVMTSDQDDIATLEREARAKREAELQASQDD
                     EKENSLQPAVNKLKKRQKGKAAAFLAICAVALIGLTWGGNWVYQNFLKQENGEKTKEVT
                     PPKKTNDYRKRTDLGMATNEPENSTEGEQAVSQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGKIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRLKNELQR"
                     /name="virB10"
     gene            18167..18358
                     /locus_tag="QDX05_RS25160"
                     /old_locus_tag="QDX05_25155"
     CDS             18167..18358
                     /locus_tag="QDX05_RS25160"
                     /old_locus_tag="QDX05_25155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000995652.1"
                     /translation="MNCKDKETWLHMLAAGHMGGLAGNPNEAAAQDAYQRLIKNKTAQA
                     VLQRCTTRITLKGANDDR"
                     /name="hypothetical protein"
     gene            18348..19373
                     /gene="virB11"
                     /locus_tag="QDX05_RS25165"
                     /old_locus_tag="QDX05_25160"
     CDS             18348..19373
                     /gene="virB11"
                     /locus_tag="QDX05_RS25165"
                     /old_locus_tag="QDX05_25160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000125556.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYKSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNVRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            19370..19768
                     /locus_tag="QDX05_RS25170"
                     /old_locus_tag="QDX05_25165"
     CDS             19370..19768
                     /locus_tag="QDX05_RS25170"
                     /old_locus_tag="QDX05_25165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_021533590.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNEKLPEWNPN
                     SLIIKSPVINDKWTLSISSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFSAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            19797..20096
                     /locus_tag="QDX05_RS25175"
                     /old_locus_tag="QDX05_25170"
     CDS             19797..20096
                     /locus_tag="QDX05_RS25175"
                     /old_locus_tag="QDX05_25170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000716758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000716758.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGGEC
                     RSAEKAFFNILKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            20099..20314
                     /locus_tag="QDX05_RS25180"
                     /old_locus_tag="QDX05_25175"
     CDS             20099..20314
                     /locus_tag="QDX05_RS25180"
                     /old_locus_tag="QDX05_25175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001090643.1"
                     /translation="MNTDENMVFYLTNSDLVYSYAHKIVCSIPSGMKGNFITSIGETLE
                     DLKKRYPDIILITESEALALQSKREN"
                     /name="hypothetical protein"
     gene            20342..20647
                     /locus_tag="QDX05_RS25185"
                     /old_locus_tag="QDX05_25180"
     CDS             20342..20647
                     /locus_tag="QDX05_RS25185"
                     /old_locus_tag="QDX05_25180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000910475.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     RLMRGLIEHTVKLKSSDANKLISYAASQGYEITEDRYNAAIKAEDECLTEITRAQV"
                     /name="hypothetical protein"
     gene            21457..23184
                     /locus_tag="QDX05_RS25190"
                     /old_locus_tag="QDX05_25185"
     CDS             21457..23184
                     /locus_tag="QDX05_RS25190"
                     /old_locus_tag="QDX05_25185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_001068080.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDVPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            23194..23928
                     /gene="mobC"
                     /locus_tag="QDX05_RS25195"
                     /old_locus_tag="QDX05_25190"
     CDS             23194..23928
                     /gene="mobC"
                     /locus_tag="QDX05_RS25195"
                     /old_locus_tag="QDX05_25190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_000905147.1"
                     /translation="MLIHDFYERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RNPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGVIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDAKNREMFIFRTIDELEQ"
                     /name="mobC"
     gene            23932..24396
                     /locus_tag="QDX05_RS25200"
                     /old_locus_tag="QDX05_25195"
     CDS             23932..24396
                     /locus_tag="QDX05_RS25200"
                     /old_locus_tag="QDX05_25195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_000697615.1"
                     /translation="MKILIIFALYILSPSLYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYEHYNTDNALADLQQEARSQKRGLWADPNPVPPWEWRHK"
                     /name="thermonuclease family protein"
     Typing          23195..23925
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.361"
                     /coverage="100.0"
                     /evalue="9.03e-162"
     Typing          10321..13061
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.527"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15289..15968
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.463"
                     /coverage="100.0"
                     /evalue="4.2000000000000004e-119"
ORIGIN
        1 atgcaaacaa ttaccacacg tgaacagtta ttagtgaatg ggaaagtcct ggaaagggtt
       61 gcgacacata tcgtaactgg cgctcatggg tatgaaacgc tttgtacagg tggctataac
      121 ttacagtaca accaagagcg agtactggtt caaaattgtg aaaagctggc tgaaggcgaa
      181 ctgcccatca cctgccacac ttgtttcgct gtatggcagg atgcatacaa attcaaagat
      241 agcgactttg acataaaatc aggaaatttc actgatacag gtctgacaga tatcacaatt
      301 ggccagattt cagaaccaga agaagaaagt gtgaatattc tctatgcgga tcaatacgaa
      361 acattgccaa tagaacgcta tatgacaaat gaagaagtag gcagattagt gttcaatttt
      421 atgaaacgca ccaacggcga agcgttacta atagtgtttc cagaatatga taatggagac
      481 gataatgacg ataaaaatac tcgttgtgtc aaatgacggc catgaaaaac taattgatct
      541 aagtccagat aatgatttag ctaaaattac aaaatcattg cgtacagcag aaaacaggat
      601 ggtatgtgtt atccaggaca ataatcgtat tctccgctgg gacagaagct atgcctctcg
      661 tgccaaaaat cactggcgaa aggtagctcc cgatcgtttt gagattttag gaaccgttga
      721 acatattcat tatgttggta agtgttaata tcaggggaca gttcgtcccc tatgccattt
      781 taatgatgct ttttccagaa ttcctggtat gcctccagca actccccgtg cttcatatca
      841 ttagccgctg caatcgagcg gaactcccgt ttaacttcca tatccacata aaggttaagc
      901 tgagcttttc tcccatcagc gtttttacgc gtcggattaa atccgtgttg tgtatcctcc
      961 agacttggcg gctcgccttt ggtgttacgc ggttttggtg gtacattagc catcttatca
     1021 cctctataaa aatataatta tagaattata tatcactgtg agagtttagt cagcaagtca
     1081 ataactccct ggacaacttc gtcagctttc tgccgtggac ctggaaaagg ggattccgtc
     1141 aatgccagtc ctttatcctg tgcctggctg aacgaggtca taaaaggtat tgcgccattg
     1201 ataacttgaa caccacacgg tttaagatat tcaagcgcgg tacgatactc actttcgctt
     1261 tcactgactc cgacaaaaac tacagccatc ttatttgttg agtgtccctt gttacgcaat
     1321 gcattcacgg ttgtaaccgt cgttctcaaa tcgtccacac taaaaccaga cggtaacacg
     1381 agcaaatcaa caatttctgc caggctcaac agcgatttag ttgcataagc agcactatcg
     1441 ataacgacta aatcccatat ccctgattca atatgttttt tagcctgtga taccgttccg
     1501 catccctgaa tagtgacagg tggttcaact ttatatctca atcgccgctg tccccaatcc
     1561 aggaatgacc cctgatcaac atccatatca agccctaata ccttccagtc tgccttcgtg
     1621 tactctgtgg caatagccct gctcattgag gactttttca ccccgccttt accgttaacc
     1681 agcgcaatag ctaccgtcat acgaccccct ataaaaatat ttttatagaa aaatataatt
     1741 atagtatccg tattggtgcc aagaattgca acaactattt gaactacagg cggcaagtga
     1801 agagataact tgtgaatata aggctttcac aaccaaattc agccaaaaca aaaaatgacg
     1861 ttttattaac aaatacgcaa cataaaaaac ggtggaaaac gcccaggaaa acatgatctt
     1921 ttgagcggat tttgcagatc cgacaacgaa cggtgatccg atggtgccga taacgtccat
     1981 tatgttaaat agccccgttt cccttgaaat tataagtcgt agcttataca atcatctata
     2041 agctataact tataggaaaa gggacatgtg gactgtttat tttggcagat tatttgatga
     2101 atggtttgaa gagcaggaac tagccctaaa acgaaaagtg ctggctgaac ttaaacatct
     2161 tgaagagttt ggcccctctc tttcacggcc acatgcagat acagtgaaag ggtcacgtca
     2221 taagaatatg aaggaactac gtatacaata tgagggacac ccaatcaggg cattctttgc
     2281 atttgatcca attagacaag caatcattct ttgcgctggc gacaaaagta atgataagaa
     2341 attttacgac agaatgattc gtattgctga cgaagaattt tccactcact tagccgaact
     2401 ggagggcaaa aaatgagaac attagaagaa gtaattgcgg ctcaatcacc tgaaagtcag
     2461 gcgatcatca aagctatggc tgatgagatg attctggaaa cagggctgca aatgatgcgt
     2521 gaagaattgc agctttcaca aaaacaggtt gctgatgcaa tgggaatcag tcagcccgct
     2581 gtaactcaac tggaacagcg cggaaatgat ttgaagctgg caacgttaaa gcgttacgtt
     2641 gaagctatgg gaggaaagtt gagcctagat gttgaactcc ctaccggaaa gcgagtggcc
     2701 tttaacattt agtagaaaag gggcgaaaag ccccttttgg ggtcagacag tggttggttc
     2761 tgcggtgatc gtatcccttt tacaaagaac atattcaggg tgttttccag ccaacaacaa
     2821 taagtagtta tattcaccta cagataaaga ccttgtagct ttacctgcgc tttctttcat
     2881 ttgccaggta tttaactgat agccaaaaat ttcggcagct tccttaagcg ttaaacctgc
     2941 ggaaattctc gcctctttaa catctgccgg agttggttta gtttgcattg ttattacctc
     3001 ttgtaaataa atcagccaga ataccattat caagatccaa taattctggc aatgtaagat
     3061 tcgtatcgag caccaatttt ttaactgtct ttttcccttt aacttgctct ttatcacaag
     3121 atttcacata tgtcttaaca tactttctga ccatatacat ctgattatcc atatctactg
     3181 taacaacata agagtaacta cccttacttt taaagaaaac attatcagtt ttcataaaca
     3241 accccatata aaattcacat caacactttg ttatagtttt tttataaaac ctgccacttt
     3301 gataagttga tcaacattaa gccctctgat aaccatttca taatcatcac cattttgtag
     3361 tatttttcct gcaagtccat tatccgcatt aaatcccgtt aatgccccat accagggaga
     3421 tatagaaagc aactgtgata acatcccttt gattattcgc actttatctt gtttttcctg
     3481 taatgcgctc tcatgctccc tgagcaattc aatttcatcc agtgcattag caaggatttt
     3541 ccgagatata tcattagcaa taccaacagg attgcgcgta agagatacag tacagacgga
     3601 aggattaccg tgccatacaa gactatcaac gctaccaact ataaaaaatc tttcacgctc
     3661 cagacgaata atgatggagt atttacgaat ttctgtagaa gtcagtttaa tacgatgctg
     3721 ataattatcc agtttgttaa cacgccagcc gttcccaaga atacggcata caacttcaaa
     3781 gacaggctga tatttttctg aaaatgttgt catgctttca aatcctttac tgcgctaacg
     3841 tagccagcaa tcgcagagtg tcagctactc aatccttttc gggttcgatg cccgaaaagg
     3901 attgctggcg aggatatagg gggcttacgc ccccgtttcg ttatgctctg gcttcaactc
     3961 ttgccctgcc ttcaacttgt tgccatcctc cggcctggaa ttttccgctt gtgccatatt
     4021 ttgcgcggat ttcctctatc gtgtgctctt cacggttcca gtaactttta tgttcttctg
     4081 gacgataaaa ccattgtttt ttctttgccg cccatttaca ccctatttct tttaatgctt
     4141 ctttgtgctc gatagtattt ccactaatcc agatccagtt accaataacc tcataaacta
     4201 aaccagacaa accgtaaaga gcctttaaaa cattttctag ttcatcacca tagttatata
     4261 ttgcactttg ttcaggactt tggtactgat taatcttatc aagattcgcc attaaaaaat
     4321 cgaatgctga attaaccgcc ttcatcattt cagcacctac cggattacgg tctgggtgat
     4381 attttaatgc agctttctta aaggcgtttt tgatgtcttt ttcagtcaac tggccagaca
     4441 agccaaaaat atttaatgct tcttggatat tcattttgta gctcccgccc ctgtggggct
     4501 aagatgagag ggaaaccatt tccctctcga tgatttaatt ataccttcaa ttgcaggtat
     4561 tgcaagtttt ttagctctct ttttgaaaaa atttataatt actgtcagga catcaacatt
     4621 gcttaaaaca tttcatatcc ctgtaaataa tttaaccacc acctgaattg atcccaatcc
     4681 gtaaatttca ttgctgggat tctcgtttcc catcctttga caagtgaatc cgcaagttgt
     4741 acgatctgac ctgttgacat ttgaacacct ctctattgtt ttgagtgtcg ataaagtgat
     4801 caggttgctc gaccaacctg atcacacctt tatagaatat atggctattg catacattct
     4861 atatattctt taagattcaa aggctcctca cctattttta aatcatcaaa atacttttca
     4921 tattttttag cataatactc aatcagttca atatcttctt gcgtaatttc ccctaattct
     4981 tctattacac catttttata atctctaatc ttattgttat ctgtaaatac tacaatatat
     5041 ttttcaccag tctctatatg aattaatcca atagtacaaa gtgtcaaagt attaaaaata
     5101 aaaatctgtt gcgtggttga ttcaatataa ggtaagcgag ccatttttaa actccacttg
     5161 ctttagattt ggattaaata aagagccata taacggggca attgccccgt tgaggactta
     5221 cagcaacgtt ttgtaatggg ctaaaagcgc ttccagttca gtcgctttct ttctgaaaac
     5281 aggggaatgg gactctaccg catcaatcag tgcgtcaagt tctgttgtga tttcctgcaa
     5341 agtgcttaaa aattctgtac cctcctggtt ggtcatccag gaaacaaagg cttttactgc
     5401 ttgttcctgc ataacttcaa tttgggtaat agcgtctttt tgctgatcgc cagttgcttt
     5461 aaatgtggtt ctaaaaataa atgcactcat tttaatctcc cgcccctgtg gggctaagtg
     5521 gaacctattt ccctttcgat gattttatta tacctgcata tgcaggtatt gcaactattt
     5581 ttcactattc gaactgaaaa attttccacc actcaccttt aattccttcg cgtatgtgct
     5641 caattcagca agggcactat tccgcttcct cacccactcg ctcactaacg ttcggtcgct
     5701 agggttgcgg cgagcggatc tactttccta gggttgtaca ccggaaacgc cgaaatttcc
     5761 gatttccaaa ctgaccccca acaggaacct ttttgtgatc tttctcgatc atattgttag
     5821 cagttagtta agttatgctc gatggtggga agatgccgcg ttagcggcat gtaaggcgcg
     5881 aaatatagtt ccatagaatc acaaatgcta aggcgcgccg atacccctaa tcaaggacgt
     5941 tcatgtcgcc aggaaccgcg tcagccccct gctaagccaa aattgcacgg aacttacagc
     6001 tacttaggtg gtaggtggtc gtagaccgtc gatgttacag cgatgatagg tgaatgattg
     6061 ttcgttttta atgaccggat atggtgtctc taatgccccg atgcttgcga ggggtgctac
     6121 ctttgaggcg cttgcgccga tgtttttcag ttatccactt gtaaaagggg ataacagtaa
     6181 tgtttttctt tttgcttctc ttttagtacg taagtaacta aaagagaagc aaaagagtaa
     6241 ttgcgtcata tcgtttgcac ttcacttatg attatccaca agctgtacat cgtttaccct
     6301 ctggccataa cctatggctg ctctttcctg agcagggagc cgcttggaaa acggaaatat
     6361 ctcacgctaa gactattttt tgtacagaga tttattatgg acgtgacgat ataccgccat
     6421 aaggcggtaa gtagccagca tcaggccgga atgggggtag gtgaatgtgc gtaatattct
     6481 tttttgcgtt gtcgagctgc gtcgcgtttt gctttcatcc tggctaatcc ggctgccgct
     6541 ttccgcgtcc agttctgaac tctgatagct ataagtctgg catcaccgga gtaaatcact
     6601 tcatcaggat ctgcctttaa cagcctggca cgttcccgat aaaccagttt taacggaatg
     6661 ccaaggatgg caaagaaatc ctcggttact tcaatgtgtt tacaggcaca ccgtgcatca
     6721 tacgggttaa acggagcctt ctctgtaatg atggcattca accaaaccag gcgatcacaa
     6781 ccacgactgg cgcgagaaat ggatttatgt cccgcatcgc tgcgtgtaac cagtccggca
     6841 cgttcggcaa gcgtttcaag gttatgcctg gtttcccacg agcgtaaatc gagatcgtcc
     6901 agaatagcta acatcaattc gcaaagagcc tctatgccaa acttgttagc ctcattaacc
     6961 caatagcggt tatgccggat acggcggcgg agttcgtttt tgattttgat acgccctgcg
     7021 accgtcgtca gcgatttaat ccagcgattg aggaaacggc gtcgcttacg cgacacaacg
     7081 ttatagcatg gactttgttt tgccacccct gacggcgata tgcgggggat taaggagttg
     7141 ttcttttcag ccaccaccgc ccgcacttat tgccggacag aggtcttgta ttgagaaatg
     7201 catttgctat aatcctttgc aggcacccag cctgctttgg accccctgat tatcttcttg
     7261 gaccggcaaa atcgaagaga gatatcaggg ggttgttgca ttcagggggg ctaaaatgct
     7321 tccccccttc ccctggacgc tgttacggga acgtcccacc caaaaatccg taaaaaccgc
     7381 acgaaaatag catgaaccca ttcgaagatc aattcatcca caaaagatcc cgccgattac
     7441 cttcctattt ttctttaaac ttcatctggt tatataattc ttaacaaaat tgagattaaa
     7501 tactgtacag catataactc acgatattaa tgctaatgta cgcatacatt agcattaata
     7561 tcgaaaagaa atcggcgata acaaacggaa aaataacgga atttaatagg gtatttaccg
     7621 ctcgccacaa ccctagcgac cgaacgttag tgagcgagtg ggtgaggaag cggaaaagcg
     7681 acttgaccaa atggagcaca tacgcactga tgcctaagca ctcattcctt tagatattca
     7741 tttaattgag caactatttt ttttacgtta tccagcttag atgccattct tcttgcttct
     7801 acttccgaat cgtaattagg gtttagctct ggactcgtac gttttcggtg aaaatcaaga
     7861 acagcctttg caaaatcatc gtcttctgta tagaaataat tttcaggata atcaagaagt
     7921 tctgcgattt tttttacaag tttaaaaggt ggttcagttc tgcctacctc gtagcttgaa
     7981 aatcgagatc gagtgttaat accttccgct acaccaagaa gttgagataa tttttcttga
     8041 gataatccag cctccatcct cgcttctttc agtcgtttag gcaccataat acaacctccc
     8101 tttttttggg aatcccatct tacagggcgt tacaggcctc aaagtcaaca taatgaatcg
     8161 gggttgattt tgaatcaagt aatgctatta tttctttaga ttcttgatat tgacacgcaa
     8221 gaattgctgt ataaaatcac aactgtgtat ttttacagtt aacacttaat gagtacgcca
     8281 gcctaagccc ggcaacttag gacggcggaa aatgggggct tgtgtccgta aggtgacgct
     8341 tatgaatgca tggtatcttc tatattgtaa taacaacgat ttagaccgca ttgcatatcg
     8401 ttgtaaaact atgaacgttg tggctttctg tccgagatac ataaagatca cacctcggaa
     8461 agattgcaac gcagtacgca aggaagaaaa agttttattt cctaactacc tcttcctcca
     8521 ttttgatgtg aatgtcacgc acacatcagc aataacctct attccaggtg caattggctt
     8581 cgtaagtttc ggttccacaa tatgtactgt accggaaaaa gtcgttatcg ctattaaatg
     8641 cgccaagata ctggcgctaa atcctgatga tgattccata gagtgccgta acatcggtag
     8701 tgacctactg gcagaaattc aacgcatatc ttcaatcatc tcaccgttag aacgtcaaac
     8761 ggccttctcc aggcttttac agaatcagta aaccagacct tcattccttc tccagtcgta
     8821 ccgctgtgct tttgcacacg gatatttcat acaggagcta taaactcatg ccgaacccta
     8881 taggccaggc taaatctaca gccgttattt acatcggcaa aaaacgctat gaaacactgg
     8941 caaaacacgc cagagatata agttatgttg cggaggtaaa tattcgtcca agtgcctttt
     9001 tgcagtacat gatcgacaaa ttaagtaatg aagctcacaa cgaaatgttg aaagagctaa
     9061 tgtcaaaaga ggataaataa atgcccaaac ccacctataa cgtatacgtc acacaggaag
     9121 ttcccactga cgaaaacggc ggtaaaaata cctactggac caaggttggc gcggcattcg
     9181 cgcataacgg aaaaccagga ctgaatatta tgctcgttcc tggtattgct gtttccggca
     9241 agctggtact actcgaacct aaagaagacg ccccacaagg aaactaattt agcgagggta
     9301 ctatgctttc caccgtttca tttatggcgg tggctatgca gtgtgccgcc acagttcacc
     9361 cctccacatc actggatgtt gcgcgggtcg agtctggttt taatccctac gctattgctg
     9421 agatcatccc caaacgtgaa cgccagccag gcgacaaggg ctttatctca catatgccaa
     9481 aaactaagga ggatgcatta agcatcgtca aacagataga ggcaaaaggt cgtcgctatt
     9541 ctgttggtct gatgcaaatc acaagtacaa attttaatag ttacgccgta acggctgctg
     9601 acctgttcaa cccgtgcaca aatctttctg tttttgaaaa gatcatcact gattgctacc
     9661 agcgaggcgg cacactgaaa cgggcgctga gttgttatta ctctggaaat tttactacag
     9721 gacaacaacc agaagctgcg ttatccagaa ccagttacat acagcgaatt ggttactcac
     9781 ctgaaaagcc ccgctatgtc gttcctggaa ccagggatga tatcgcaact caatcggcca
     9841 ttctgaatgc aacacccgtt gaagctccga cacgccctcg cgttgtctgg cctggcgcaa
     9901 tcgtgcgcgg ggttcctgct caactgcgcc agaaaaaggc agataccgtt tattaccccg
     9961 cacaagttat acgcggaaac agattttcaa ctgaaaaaga ggattaaccg atgattaaca
    10021 aattaaaggc catttgcagc cgcgcatctg cttatattct ggctccgtta gtaagtgttg
    10081 tcagtcccgt tttcgcggct gacggtttca gccgagcaaa taccatcatg gaaaaggttt
    10141 cgaatggtct gcatggtctg gcagccgtca ccatcaccgt cgctgtgatc tggattggct
    10201 ataagactct gtggaaaggc gaaagcctgt cgcagtgcgg ttacatcatc attggcggca
    10261 ttttaattgg cggaggcagt gaaattggcg ctctgctaat gagctaagag gccgaacata
    10321 tggcaaagct gcttaaggcg atgaaacgtc cggcggcgct gtggggggtg ccaatggtgc
    10381 ccctgctgac tgtcgtgggc gtgacaatta ttgttgctat ctggacttcc atagccctac
    10441 ttctcttcct ccctattgag tttctggtta tgaaatcact aaccagaaat gaacctctga
    10501 gatttaacct gatagctgtc tggctaaggg taaggggtaa tccggtagca aaccgtttat
    10561 ttggcgcaac cgcatttatg cctgttgaac ataatgctgt tgatatccag gagtttatcg
    10621 atgcgatgaa gctaaaccaa tgtgccacca taaaaaaata cattccttac tcgtcacata
    10681 ttcaccctaa tgttgtccgt tcactgaata gcgatttttt ctgtacctgg gaactgacag
    10741 gaacgccgtt tgattgtgaa tctgacgaga cactacagtt cggtacaaac cagttgcacg
    10801 ggctaatacg ctcatttgaa ggctttccgg ttacatttta tgtacataac agccgtgaac
    10861 agtttacgga ctcactgcat aaggtttcag gaaaccctta cgcggatacc gtgagcgaac
    10921 gctattacgc atcactgaat aaaaggccat tccgacgtaa ccgcctgttt gtgaccatct
    10981 gctatcgtcc gtttgccagt ctggataagg caaaccgtaa acgtatgaaa gacggtcaga
    11041 agctaaaaga gatagacagc gcattacttg aagtgctgga aatcaaaagt acgctggata
    11101 cagccttatc ccgttatggt gctcacgcgc tcggtacttt caccgaaaac gaggctgtat
    11161 tctcgtccca actggcattt tatgaatacc ttctcacgca tcaatggcga aaagtcagag
    11221 ttacacgtac ccccgcttac aacgtaatgg gaaatgttgc gctgtacttc tccgccgaat
    11281 cagggcaaat aaatcatgtt aatggcactc aatatttccg tggtctggag gttaaagagt
    11341 tttcggaaga aaccgcaacg ggcatgacag actccttact gtacgcgccg tgcgattatg
    11401 tgattacaca atcctatacc tgcatgtccc gtgaggaagc gaaaaaggcg attaagcgca
    11461 cccgacggct gatgatgagt gctgatgatg atgctgtatc tcaacgtttg gatctcgatg
    11521 tggcgcttga cctgctcacc tccggtaaaa tcgcctacgg taaacatcat ttatcaatta
    11581 tggtgttttc gccgtcactg gaaagtctga ttgcagacac aaacgagatc agcaatgcac
    11641 tcaacaatat agggataacc cctgttcctg ctgaaatctc attgtctgcg gcctatatgg
    11701 ctcaattacc aggcaattac aatctgcggc cacgagcggg agagttgagt agcctgaact
    11761 ttgttgaact ggcatcactt cataatttct atccaggaaa acgcgacaaa gccccgtggg
    11821 gtgacgcgat ggctctggtg cgaaccccgt caggtgatgg ctactatctg aatctgcata
    11881 acactctggc agataaagac gagttcaacg aaaaaaatcc tgcaagtacc tgcattctgg
    11941 gtacaaacgg ctcaggtaaa acaatgctga tgacgttttt acaaatcaat cagcaaaaat
    12001 ataaccgtga tgacagcttt tcaccggatg ccaggactaa acgactaacc acagtttacc
    12061 tcgataaaga ccgtggtgct gaaatcaaca ttcgcgcact tggaggaaag tactacaggg
    12121 tattcagcgg tgagccaaca ggctggaatc cgtttgctct gccagccact aagcgaaaca
    12181 tcaatttcat taagcaactg atgaaaatcc tttgtacccg caacggtgca accataacgc
    12241 cacgtgatga acgtcgcctc aatgatgctg taaatgccgt catgagtgac gagcctcaat
    12301 atcgcgtcta cggcataacc cgaatgctgg agaacctacc ggaaccggca acgcgtgaag
    12361 cgcaagaaaa tggcctgagt atccgtcttt cacagtgggc gcgcggtggt gaatttggtt
    12421 gggtgtttga taacgaacac gacactttcg atatcagcaa ctgcgataat ttcggaattg
    12481 acgggactga atttctggat gacccgaatg tctgcgcccc tatctcgttt tatctgctgt
    12541 accggataac cagcctgctg gatggcagac gacttgttat tttcatggat gaattctgga
    12601 agtggttacg cgaccctgta tttaaggatt ttgcgtataa caagctgaaa actatccgaa
    12661 aactgaacgg tatgctggtt gttggcacgc aatctccagc ggaaataatc aaggatgaga
    12721 tagctccggc agttattgag caatgtggta ctcaaatact ggccgccaac ccaagcgcag
    12781 atcgttctca ttacgtggat ggaatgaaat ttgaaccaga agtgtttgat gtcattaaag
    12841 gacttgatcc acaggcgcga cagtatgtcg ttgtcaaaaa tcagttccgc cgtggagata
    12901 caaaacgctt tgcagcccgt atcacgctgg atctgtctgg tatcggcaga tacacaaaag
    12961 taatgagcgg cgacgcacct aacctggaaa tattcgaatc actctatcag gagggaatga
    13021 agcccagcga ctggctggat tcctacctag ctaaagcact ataaccaagg agatatcgat
    13081 gaaaagattt cgccccctta ttctggcggt tcttattgcc agcccgatag taaacgctgc
    13141 tggtataccc gtgtttgatg caacagccag actagagaat attcgccagt ggacaaaaga
    13201 agccaatcaa tggctacaga cggtacaaca ctataaagac cagctacagg cgtatcaaaa
    13261 acaactggaa acagttacag gcatccgtga cattcaggcg ttcgttaatc aggccaaaag
    13321 ccttaaagct gacctggata aactacgtaa gccagggcaa gccctgaacg atttgctctt
    13381 atccggcggt tcttctggcc aatttgatga actgtacaac aaatacaaga ttttcgataa
    13441 ctgcaatgct gaacaatcaa aaagttatgc caatacatgc agacaagagg tcatcaacaa
    13501 agcaatacaa atcgaacaaa ccaatgaagt acaaacccag attggtgaga tgcttggtga
    13561 gatcaacgaa ttatcagacc gtgtagcaaa tgccaaagat atgaaagagg cccaagactt
    13621 agcaaacagt attcagttaa aatctgtgat gctaaatacg ctcacgaccc aatgggaaat
    13681 gaacgtaaaa gcggcggaga agcgtgaaaa gatgcttgct gatgaacgcc gtaagaaatg
    13741 gaatcagcag caattaaacg caccagaaat aatgtttaat tagcaggtga cttaatgaag
    13801 aaaatcattt tatttacaat tatttcaggc ctgatggcgt taacttcagg atgtaaggaa
    13861 gaagctaaaa caacaaaatg gtatcgtgaa catcctgatg aactcaaagt tgtttatgct
    13921 gaatgccaga aaacaggtag cgcatctgaa aactgcaaac atgccaatga agctcattgg
    13981 caaattcaac aattaaatgc acctgaaata agtttcaact aaagggcgtt tatcatggcc
    14041 ggtatatttt cttctgtcga aaaaaatatc atcggtggga taactgacgc gactaatggt
    14101 ttgatgatgt cttattcgtc aatgatgatg gggctggcgg ctacgtcagc cactatctac
    14161 attatgtggc gaggatatca aaccttagcg ggaaagctgt ctacaccaat ggaagatgtt
    14221 atgtgggata taatgaggat ggctatcatt ttatcctttg tagcaaacat taacggatat
    14281 cttgatggtg tcattgatgc tgtaaatgga ataaaagaag gtttttccag tagcacaagc
    14341 atctggcaat tacttgatac tctatggaac agcgcaagag ttttaggtaa aacgttacat
    14401 gatctagaca actccgaatt tatcaaagag gaaggcacaa ttgctgaatt atttgtatgg
    14461 ggtggtgtct ttgtcttaat gattatcaca gcattcgtat ctatgattgc ggagatcatg
    14521 atcttattgt taggtattac cgcaccaata tttatatttt gcctgatgta tggcttttta
    14581 cggccaatgt ttaataactg gcttcaaaat atatttgctg caatactaac aattatgttt
    14641 tcagccttag ctctgcgaat tgtaattggt tttcttacat ccagaatgtc agaagcagtg
    14701 acccaagcca gcaaagcaaa cattgtagaa cttggcgctc aagtttgtct tgccggagta
    14761 tgcgctgcaa tactggtgta catgtccgca aaactagctg gggcacttgc aggagcaagt
    14821 gctacagcca ctatgcaagg tgcggcggct ctcggcattg gcgctgctgc atacggcgct
    14881 ggaaagatgt taaaggaggc aggaaaagta ttacctaaag aagtagcaag cccaagtaat
    14941 aaagggttag gagatccaca atcgcgcata gtatttaacg ctgctgatgc acgtaaacac
    15001 gctatagaac aaatgatagc gcgtaatgaa gcgcggatgc tgacagatca atcagcacca
    15061 aaactaccgc catcaattaa acgtttacct cctccaagat aactataaaa atataattat
    15121 atttttatag aaatacaaaa aggtacataa aatgaaacgc ttaatcgcgc tggctttgct
    15181 gtgcgtgctt tctggctgcg cacaaaaatc taaatctctg ccgcacgcat tcagcggtca
    15241 gggtagccct gtaaacacac cccaaattat cgcggagcta accacacatg actgaacaga
    15301 aattaattgc tgattcccgc tcgtttgagc agcaaatgat tgacagggat aaacgcgcca
    15361 caaaagcagg ctttctggtc ggtggagcag ggttattaat cactatcctg tcactgatcg
    15421 cgatagtgat tatgttgcca cttaaacaaa caacagttga actctatacc gtagataatc
    15481 ataccggacg agtggaacac gttacccgtg catcaaaaac agccctgaca gcggaagaag
    15541 cctaccaaaa agctatggcc gccaattacg ttaaattacg tgaacggtac gtttatcctg
    15601 cattacagga cgattacgag acagtacaga tctacaactc accacaggta aacgacgact
    15661 acctggcact gtacgccgga aaaaacgcac cagacaaagt ttataataac gcggctcaca
    15721 ccgtgaaaat tgaaattatt tctgagcaga taacgaatgc aacagcacca gacaaagtag
    15781 ccaccgttcg ttataaaaaa ataattcgtc gcatggctga taacagtatt cgcaatgaat
    15841 actgggatgc acgtttcacc ttccattcag accctgaaaa agaaatgtca gatgttgagc
    15901 gggaaataaa cccgttcgga ttcaccgtaa caagctggca gactgaccgc gaaatcaggg
    15961 gaggcgagta atgagaaaac tgacgttaat taccctgata ataatgctga acagccaggc
    16021 atgggccgca gctacaccac aagcgagccg ttatgatgca cgtatccagc aggtcattta
    16081 taacccgcag aatgttaccg ttgtaaacac aaaaccagga tttatgacga ctctggtttt
    16141 tgataacgat gaagctgtta tcagtgccag tcctggcttt gatgaagcat gggaagccag
    16201 agcagatgca aacagggtaa acattcgtcc ggttgcgctc acacagggcg cacctggtga
    16261 agacggtaat acaacacagg ttgttatccc gccgaacagc cgtgactggc ataccaatat
    16321 gctgattgtg acaaataagc gcctgtacaa cgttgagctg aatgtcattg atgaaaaatc
    16381 gccacaacag cccgcatacc tggtgagtta ccgctatcca ggagacgaac gtaacagagc
    16441 taataaggaa gcagcagcgc gtcagaaaga atgggaacaa aagcaggaac aaacccagat
    16501 tcagaaagca ctgagaaccg cacaaacccc gcgtaactgg gactacacga aatatccagg
    16561 aaaagacagt tacaacattg aacctgattt tgcctacgac gacggtcgct ttacgtttct
    16621 cggattctca cccaacaaat cagttccatc agttaccaaa gaacagaacg gccaggaata
    16681 cgtggttaac agcagtatac agcgtaaggg caattttacc gttctcgtta tccaggaaat
    16741 cacaccacgg cttgtattac gttccggtga tgccgtagtg gggctgaaaa ataacggctt
    16801 tggaaaagta cacgcggctg ataattcaac cgtatctgac aaggtggagc gcgttgaaaa
    16861 aacagataac acctaatcta taaaaatata attatatttt tatataagga ctcatatatg
    16921 actgacgaaa ataaatcccc ctctacggaa gaagaaaagc cagtgatgac atctgatcag
    16981 gatgatatcg ccacgctgga acgagaagcc agagcaaaac gtgaggctga attacaagca
    17041 tcacaggacg atgaaaagga gaactcatta caaccagcag taaacaaact gaaaaaacgt
    17101 cagaagggga aagcagcggc ctttctggca atatgcgcag tagccctgat tggcctgaca
    17161 tggggcggta actgggtata tcaaaacttc ctgaagcaag aaaatggaga gaaaacaaag
    17221 gaggttacac cacctaaaaa aacgaatgac taccggaaac gaaccgattt aggcatggcc
    17281 accaatgagc cggaaaattc gactgagggt gagcaagctg ttagccagga taacacgggc
    17341 aatgtatccg gtactgccgg acagatgaaa acatttgagc caccacaact gaataaggcc
    17401 agcttccttg ttcgtcgtaa taatacggcc agcccccaaa atcaggtaaa aacaagacaa
    17461 caggaaatga tactggctgc ggaaaacaac gccacacagc ctacagacag tacagcaacc
    17521 acaacacaac atggcactgc atcacaggca atttcccccg caacagtgcg aagaatcccc
    17581 tacaaccctg atttgtacat accggaaaac acagtcattc catgctctat ggattaccgc
    17641 tttgtttccg atcgcgctgg aaaaatacga tgtacggtag ctaaagatat ctggagtgcc
    17701 agcggcaata caaaacttat cgagaaggga accacagcaa caggaatata ccagacagga
    17761 attacgcaag ggcaggggcg cgcttttatc atgatgacaa aattacgcac ccgacagcga
    17821 ccatatctgg atattccgct gattgatacc aacgccgctg gcgagcttgg agaatcaggt
    17881 gttgatggat ggattgatac ccacttctgg gagaggtttg gcggcgcatt aatggtcggc
    17941 atgatcccag atattggcgc atgggcatca aacaatgcgg gtaaaaaaga ccgcaataca
    18001 gactatacag agaacagccg ccaggctatg gcggatatgg ctcgaaccac gctggaaaac
    18061 agtatcaata tcccccctac gctctacaaa aaccagggcg aaattatcaa cctgattaca
    18121 gggcaggata ttgacttttc aaatatctac acgctgaggc tgaaaaatga actgcaaaga
    18181 taaagagact tggttgcaca tgctcgccgc cggacacatg gggggtctcg ccgggaaccc
    18241 gaacgaagcc gccgcacagg atgcttacca gcgtctgatt aaaaacaaaa ccgcacaggc
    18301 cgttttgcag cggtgtacca ccagaatcac actgaaagga gcaaacgatg accgctaaga
    18361 atatttccct ggaccgctat aaacagcgat tttttggtga ctttctggaa ttaccaggac
    18421 tgacagaaat agctgttaat cgtccaggtg aactctggac aaagatagat ggtgtctggg
    18481 ggcaacatac cgttgatctg aaatttgacg attgctataa ctttgctcgg tgtcttgcaa
    18541 aacaccataa cgataatatc gaggatatca aaccaggact ttctgcaacc ctggaatcag
    18601 gagaacgatg tcaggttgtc gtacctccgg cgtgcgaacg tgacacgatc tcaatcacga
    18661 tccgtaaacc gtcaaaaatt caaattccgc atcaggcata tattgatagc ggtttttata
    18721 accgcgtcac aggcattgaa aaagcatcca cacataacga agaattgatt gaattataca
    18781 aatcaaaaaa cattcctttg tttatggaaa aatgtgtgga gtatggaaaa acattagccg
    18841 tcgcaggtga aaccagtacg ggtaaaacaa catacatgaa aatgttgata caatatatac
    18901 ccgtccattt acgcataacg acgatagaag acaacccaga gataatattc tacaaacata
    18961 agaactatgt tcatctgttt tatccttctg agtcatccga tgaaaaaggt tctgttgtaa
    19021 caccagcggc gcttatacgc tggaattacc ggatgaatcc agacagaatt ttattaacag
    19081 aagtgagggg tggagaggca tgggattttc tgaaaataac ggggtcaggc catgaaggaa
    19141 gtatgacctc cattcatgct ggttcagccc atgaagcaat cgacggtttt attacccgct
    19201 gtactgaaaa cccacagtgt gcgcaattac catattcatt cttgctacgt aaagttctcg
    19261 actctctgga tgttgttgtg agcattgatt tagatggaaa cgtacgccgt atgaatgata
    19321 tttatttccg accgttacac cgcaatcaat attacgagga aatgaaagta tgataaagca
    19381 tatactggtt actgtgcttg taacactaat taccggatgt tcctcaccgc ctccaccagt
    19441 acccgtggaa tggaataaaa agccggtatc gcttaacgag aaacttcctg aatggaaccc
    19501 caatagctta ataataaaat cgcctgttat taatgacaaa tggacgttat ccattagctc
    19561 acaagatttc aataaagaag attggatgcc atctgtcttt tatgccattg ctcactcaac
    19621 acaaatcaca gtagcaacaa agtcaggcgc tgattatttc agtgcaaaaa actggttgta
    19681 tcatcatggt gcaaacgggg taattatata tcaccccatc acaaattgtc ttacgtgcaa
    19741 tgaaacaacc atctactttt cgcgttaaca caaaatatta aacaaagggt tctgacatga
    19801 aaaaaattgc agcaataaca atgtttgttt taacaaccgc cacacctgtt tactcttatg
    19861 ccgcagaccc atgcgaggtt gttttatgta tgtacggaaa agctacagga aacagcggag
    19921 gtggcgaatg cagatcagca gaaaaagcat tcttcaacat tcttaagaaa aagaaaggtt
    19981 caatacgatg gagtaaaaca tttgatgcac gtaaagcatt tttaaatcag tgttcatccg
    20041 ctgatcccgc agctatatca aaaataatga gtaagtttgg tagagttcga gggtaaatat
    20101 gaatacagat gaaaacatgg tattttatct gacaaactcc gatcttgttt atagctatgc
    20161 acacaagata gtgtgctcca ttccatcagg aatgaaaggg aatttcatta cttctatcgg
    20221 cgaaacgctt gaagatttaa agaaacgata tcctgatatt attctcatta cagaatcgga
    20281 agcattagca ttgcaatcga agagggaaaa ttaacatatt ctttcagatc tggagaatcc
    20341 tatgttaaaa gaagatatgt tcattaataa tattcattca aggaatcagg acagaatcca
    20401 tgtaaaaaga gtctttgatg atattagtaa taaagcaaac aggggatgcg ggctatatta
    20461 tgaaatatat caagcgaggt taatgcgagg gttaattgag cacacagtaa aactgaaaag
    20521 ttctgatgcc aataagctga ttagttacgc tgcttcacaa ggttatgaaa taacagaaga
    20581 cagatataat gctgcaataa aagccgagga tgaatgtctg actgaaataa cacgggcaca
    20641 ggtctgaggc agaggattgc gtagcaaccc gaagggcggg gcaaattcgc tttgcgaatt
    20701 tgggcgagtc cgacgcaggg cgtggtgcag ttcaggcttt ctttatttct ggcttcaatt
    20761 tcgaagaaat tgttaagaca ggaataaaga aagtggtgcg tggacagaaa attcaatttc
    20821 gaagaaattg ttaattttca ggcaccacgc ccacccgcga acattcgccc caagcgaatt
    20881 gaagcgggcc ggggggagcc gcaaaaattt ttccgcccca gcgagaaaaa aggcacgccc
    20941 acgtgccggt ttttgtgggg ggcttgcccc gcacaccgtc gggccaggta atatttcccg
    21001 ccccagcggg ggatattacc gattaggcgc gaccaccccc tttaaagcag cgttccaatt
    21061 ttttcgagct tgcgaagaaa aaataggcta aacgcgcgtc ttaaaggggg tggtcgcgcg
    21121 tagcgcgcga cggtgtgccg cctttgacct tgggggtttt ggtccggcgt ccagacgggc
    21181 cattaccccc atgtgacgtg aaggactggc gtttcagcca ggccgaaacg gcacacgccg
    21241 ttgcccgttc ttcgggcttt caggagccag acgataactt atcggctggc ttctgaaaga
    21301 acggataacg ggcatgatcg ccttaggcga tcacaacgtt tttggctttt attggggtac
    21361 aataatgggg tacagctatg gggtacatta tatcccccat tactgtaccc cattgtcgta
    21421 ccccatagat tcactttatg aatggggaaa acaaatatga atccacatct aatgcaaaag
    21481 ctgaatggta ttgctgatgc cttttcaata tttctgttat ggctacagaa cagccctgtc
    21541 atattgtcat tactggcagg actaacacta ccatttatat tcaacctacc acgagaggaa
    21601 agaaaaaacg ctcccttctg gttaaaatct gttgcgtgcg tgtccatttt ctttttcata
    21661 ttcggcacaa tgtcaccact tagtattcat ggtctgagct acctatttga cgttctcgat
    21721 cccaatacac tacttagaat accattatgg ataatcacaa ttctctttac actagctgga
    21781 ttagcttttc atttgaccgc gcgacgatta ttagcaggtg aaatagacag cctgaaacac
    21841 agaatgataa agaaaagcaa acttgagaga aatacaagaa cagatgttcg caaagtaaaa
    21901 gaattgttgc cagacagcat agaatacaat cccctagatt acattgattt gaaaaaaggg
    21961 gttttcattg gcttagacaa agacgaccaa ccgcaatata taacaataaa agaatttcag
    22021 aaacaacatg cagcaatcat aggtacaaca ggttccggta agggcattac cgcatcggtt
    22081 ttgctttatc aggcaattct gttaggcgag gctgtttttg ttgaagatcc aaaagatgat
    22141 gaatgggctg tgcatgttct tagggaagca tgtaaaaaag caggaaagaa atttgttgta
    22201 attaatttaa acagaaccaa ccatcaactt gacttacttg ctgacatatc acatgaacaa
    22261 ttagaagaat tatttaatgc aggatttagt ctatcaaaaa aaggagaggc cgcagatttt
    22321 tatcgtatag ctgatcgccg cgcagccaga aatgtagccg caattcataa aaccggaatg
    22381 acactgtatg atttattcaa cgatgacaac gtaaaatcaa taggagaaga tgccccagca
    22441 tttttaggtg aactagaaga aattgctctt gtaaattccg tcaatgcaaa aaatggattt
    22501 tctcttaaag agatttttga taatggagga tgctgctata tcattgggtc aacccgaaat
    22561 caaaaaatta tttctgcaca acgcatgata cttacgcgtt tgattcagat agctgaaacc
    22621 agagacagaa taaacacaac tccacgtgtt gttgcaattt ttcttgatga gttgaaatat
    22681 catatttcac gcccgacaat ggaaggatta ggtacagcac gagataaaag tgtgcatata
    22741 tttatggcct tccaggcaat agatgattta agagattgcc cttctgatct taatggcgat
    22801 tctgtaattg gtgctgttat tgaaaacgca aaattcaagt taatctataa aatccagaat
    22861 ccagaaacag cagagtgggc agctaaaatg actggttcaa tattagttga cgatgaaatg
    22921 aggaaggtga gaaccgactt atcattaaca gaaaaagttg atactgaccg catgataaga
    22981 caggcagaaa gttattatgt agacagtaat atgtttttaa atctacctga aagagtagga
    23041 tttgtgttca catcaaaaga tttaccaaaa gcaactaaaa tgtctcatat accagcaaac
    23101 aaagaaacca ttgaattgct atcttttgag acagaacaaa tagaacaaca caataacaac
    23161 gatgtgcctt ccagtggttt atgaggtttt actatgttaa ttcatgattt ttacgaaaga
    23221 aaaagaatat cagctaacaa catgctttgt cttttaaatt tccttaagga tgaaacgtat
    23281 tcagactttc acattataaa aagaaaatta ggattcacaa aaaaaagcag aaacccagta
    23341 tataaattac taaacaaggc tcttaaagaa ggttttatta tcaaacatga aataccatca
    23401 tcaaaaagaa aattaactgt ttggggtatt actatgcaag gattagcaat ggttgtaaaa
    23461 gccgatgaca ttacgttccc tagttatttc gaacccagca aactaaaata ctggactctt
    23521 gagcatcgtc ttttaaatca gcgagtgaga atatctctgg aaagtaaagg cgctactgaa
    23581 tggattaacg gtgatagtgc agccttcatc gcacgttatt ccggctgttc ccatcgccct
    23641 gatggagtaa taaaacaacc aactggcgca ataatggcta ttgaaacaga acgaacaatg
    23701 aaaactcgtg ctcgctatat aagcattata aacagtcatc ttacggcaag agataaagga
    23761 aactggcatt atgctttgta cgtcatgcct gacaccaaaa gtaaagaatc attaatcaga
    23821 ctgttcgact caatcaaaac tgtaatgagg aataatacac ctgtgccttt tgatgcaaaa
    23881 aacagagaga tgtttatttt tagaacaatt gatgaactgg aacaatagtt gatgaaaata
    23941 ttaatcatat tcgcattata tatcttgtcg ccttcactat atgccaatgc agcggatata
    24001 cagggaaaag ttattcgtgt acttgacggc gataccatcg aaattttaca gaataaaacg
    24061 ccagtaagga ttcgtctggc caatattgat gcaccggaaa agaaacaggc ttacggacgc
    24121 tggtcaactg accaacttaa aagcctgatt gccggacaat ccgtcagggt gacatattca
    24181 cacaacgacc gttacggtcg cattatcgga cgtgtattca caacaggcgg tagtgaggct
    24241 aaccgcttta tggtgcaatc gggtgctgca tgggtgtatg agcattacaa cacagataac
    24301 gctctggcag atctacaaca ggaagctcgc tcacaaaaac gaggtttgtg ggctgacccc
    24361 aatcccgttc caccgtggga atggcgacat aaataggaga ttgac
//
