LOCUS       NZ_CP122577             6535 bp    DNA     circular CON 31-MAY-2024
DEFINITION  Klebsiella pneumoniae strain KP-2683-1 plasmid pKP-2683-1-6.5,
            complete sequence.
ACCESSION   NZ_CP122577
VERSION     NZ_CP122577.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN34111323
            Assembly: GCF_029853855.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6535)
  AUTHORS   Lin,Y. and Chen,L.
  TITLE     Emergence of OXA-48 producing hypervirulent Klebsiella pneumoniae
            strains in Taiwan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6535)
  AUTHORS   Lin,Y. and Chen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2023) HMH-CDI, Hackensack-Meridian Health Center
            for Discovery and Innovation, 111 ideation way, Nutley, NJ 07110,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-SEP-2022
            Assembly Method                   :: Unicycler v. v0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology :: Oxford Nanopore MiniION and Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029853855.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 06:43:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,660
            CDSs (total)                      :: 5,540
            Genes (coding)                    :: 5,395
            CDSs (with protein)               :: 5,395
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 71 of 145
            Pseudo Genes (incomplete)         :: 80 of 145
            Pseudo Genes (internal stop)      :: 33 of 145
            Pseudo Genes (multiple problems)  :: 36 of 145
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP122577.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6535
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP-2683-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKP-2683-1-6.5"
                     /geo_loc_name="Taiwan"
     gene            complement(join(6280..6535,1..287))
                     /locus_tag="QDV38_RS02835"
                     /old_locus_tag="QDV38_02840"
     CDS             complement(join(6280..6535,1..287))
                     /locus_tag="QDV38_RS02835"
                     /old_locus_tag="QDV38_02840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase growth adaptation protein"
                     /protein_id="WP_186476026.1"
                     /translation="MNIDEVAKWRPFTDPDGNIWDLSFLDAHEVTYTHCSPGKPDIVYK
                     FTVSYSFHCFCKDYPEQTEEEKLSLMYDAGKDARPFCKIRYALARDKLRAIIEGLGNAK
                     VIHAGYGSYAVVEITVDEGESEFYFVPFRVYRERKKLRLHVTSAYPVSERPSGKPVSFF
                     KIAHNLLRGQPLPKPHM"
                     /name="stationary phase growth adaptation protein"
     gene            complement(940..1239)
                     /locus_tag="QDV38_RS02840"
                     /old_locus_tag="QDV38_02845"
     CDS             complement(940..1239)
                     /locus_tag="QDV38_RS02840"
                     /old_locus_tag="QDV38_02845"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_186552888.1"
                     /translation="MAFGNAYLVDDMTIQNFRIGFERIVFLGLLFFAVKAVLLFGIILF
                     HHGWNVWQRDGAFECLIIFAGIMISSQVLLWVAYGFAGKPFKPNFNPLTYVHRL"
                     /name="hypothetical protein"
     gene            complement(1208..1657)
                     /locus_tag="QDV38_RS02845"
                     /old_locus_tag="QDV38_02850"
     CDS             complement(1208..1657)
                     /locus_tag="QDV38_RS02845"
                     /old_locus_tag="QDV38_02850"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_065878593.1"
                     /translation="MSKQSQNLLNLTQAAEAVGITRKTLYSHIDKGFVSVTRQQGKRYV
                     DVSELIRHYGSVSLPEEKINAVTRSQTKRDDDTILAMQRELVELRKLIEKQQLLLEDKQ
                     EADRLREQVTGLQNERDAAAQELKKVKAELEAKRNNGFWKRLFGG"
                     /name="helix-turn-helix domain-containing protein"
     gene            1791..2135
                     /locus_tag="QDV38_RS02850"
                     /old_locus_tag="QDV38_02855"
     CDS             1791..2135
                     /locus_tag="QDV38_RS02850"
                     /old_locus_tag="QDV38_02855"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142499555.1"
                     /translation="MTSTPMLPTFAAPTDEERDTLSAILNDNGLRATTPRINVLHFLNI
                     ADVPVTAEAVSRCVDLPLSTAYRTLTVLEVTHLAGVTFARGDVTRWFRFTPDTPQHCPA
                     CGQSFYGEYA"
                     /name="hypothetical protein"
     gene            2253..2759
                     /locus_tag="QDV38_RS02855"
                     /old_locus_tag="QDV38_02860"
     CDS             2253..2759
                     /locus_tag="QDV38_RS02855"
                     /old_locus_tag="QDV38_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_154066764.1"
                     /translation="MTTKRQAQRATESDLQAFMNDAADRFKPDAAVLAARIDTAVQRYF
                     VTSTTQRFNAPAPLAMQQLQERILEGWRYDIGIPQSVYLAGTGNMSITLRKPAELVEQE
                     ITDLKRQVEDSYHNELAAAIEREVDKLVQDAADEAQRRAEEAAAAERDAMRQRLKDMLL
                     TGATA"
                     /name="hypothetical protein"
     gene            2756..2908
                     /locus_tag="QDV38_RS02860"
                     /old_locus_tag="QDV38_02865"
     CDS             2756..2908
                     /locus_tag="QDV38_RS02860"
                     /old_locus_tag="QDV38_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020244645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_185954838.1"
                     /translation="MTVTKVKSGPPAPAHIDPDALERAIAAARKIKEANPDRYKSLPVQ
                     PEVKQ"
                     /name="hypothetical protein"
     gene            2905..3102
                     /locus_tag="QDV38_RS02865"
                     /old_locus_tag="QDV38_02870"
     CDS             2905..3102
                     /locus_tag="QDV38_RS02865"
                     /old_locus_tag="QDV38_02870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015689669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142499558.1"
                     /translation="MKIYDITVTGTTADWLTATRGNMPLPVFVRRLLTEIASNPEKYND
                     LTQTLNDSVECKCQTRTTKK"
                     /name="hypothetical protein"
     gene            3075..4418
                     /locus_tag="QDV38_RS02870"
                     /old_locus_tag="QDV38_02875"
     CDS             3075..4418
                     /locus_tag="QDV38_RS02870"
                     /old_locus_tag="QDV38_02875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase-helicase family protein"
                     /protein_id="WP_142499557.1"
                     /translation="MPNPNNEKIIDNAANDSDGISIDEKNGHERLAHQFAEYLINQGFI
                     YLSRKNGADLYSTLTGKFHPFHAETNLYQQWLRKQSEHRRSGHNPLLHDILRQRIKYAS
                     AREFIPGGARPLVYEADGVPVLNTWKPYEPQTTAAAGADLSLWVEYLERLFPDADERHT
                     VVQWLAHMFQHPEVKPSWHLMLTSATGTGKGFLFDQVLSPLLCGQASLLSSYDKLTGQF
                     STVIANNLLVFLDDCRSSSKSLHTRLKSLLTERRQQIEEKQEQARMVSTYTRFILASNE
                     RRPIRFSPNERERRWFVVRFMEHRHNPVETGEFIGRLAQWLTQDGSLDAIYWWLMACDL
                     TGFNPHHCCATETLAEMQEQSRSMLDIELSDWLESNRVFKMETVRLLFDAPPDLIKHRL
                     EELGYRQAPINTNGAGVDRSRYWFPADWKPKQAAQWLEDAADGTTEQF"
                     /name="primase-helicase family protein"
     gene            complement(4975..5847)
                     /locus_tag="QDV38_RS02875"
                     /old_locus_tag="QDV38_02880"
     CDS             complement(4975..5847)
                     /locus_tag="QDV38_RS02875"
                     /old_locus_tag="QDV38_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005782831.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_232627572.1"
                     /translation="MIKVIDSDFQISCYKSINYVLSVFFIICLPFGKFMIQFVHDPFGG
                     VNMQVVTYRRVSTERQGRSGLGLEAQTDYIAHAVRQHGWEIIDEFTDEGVSGSLEPMQR
                     NGLRQAIELCKRTGACLLVAKLDRLSRSVLDIATLVEQLPCIKVATMPTADKFQLHLYA
                     ALAEQERDFIKQRTSDALASLKARAAAGDELSQQKVQTWSDNIAAAHASGVNRQRSIKV
                     RAVRADAFAATVEDNILAARTRGHTTLQAIANYLNERGITTRRGKRWTPAAVSRVESRF
                     PTPPDRSAM"
                     /name="recombinase family protein"
ORIGIN
        1 atggctctaa gtttgtctcg agcaagagca tatcggatct tacaaaatgg cctcgcgtct
       61 ttgcctgcgt catacatcaa cgataatttt tcttcctcag tctgctcagg ataatccttg
      121 caaaaacaat ggaacgagta agacacagta aacttgtaca caatgtcagg tttaccagga
      181 gaacaatgag tataagtaac ctcatgtgcg tcaagaaatg acaaatccca tatattgcca
      241 tcaggatccg taaaaggacg ccacttagca acttcatcaa tgttcacgaa aaaaacctca
      301 atacccggat ggcagaatcc gcatattcta ccagagaaga aacaagcaga cggagcgcgg
      361 aaaagaagaa aaactggcct tttacagaag gcttcgcccc tcctgacgag catcacaata
      421 cagacgctca aatcaagagt ggcgaaaccc gacacagctt aaagatcccc accgtttccg
      481 atgagtcgct ccctcgtgcg ctcctgtgtt cccgccttga cgtttgcagc cagccttgcc
      541 gctctttcta ccttgggggc gctaactctc agcttcccta tgctggcact gctcgtttta
      601 ggcggttcgc tccaagctgg actgtatgca cgaactcccc gttcagtccg accgttgcgc
      661 ctgctgggta actattctca cgattccaac cccagcggac acggcaaaac gccgctaatg
      721 gcaacagcca atacggtaac gagtaatcag gggaaggtag gtcttgcaga ttgcgctaag
      781 cgcaagtaga cttgatatac agttttggtg acgtcgttcc cccgaacacg ttaccaggtt
      841 caaagagcgc caactctgag aaccttcgaa aaaccacctt gccgggtggt tttttcgttt
      901 catggataat gcaccggtgt agcaacgccg tcaaattaat taaagccgat gcacatatgt
      961 taacggatta aagttaggct taaacggttt ccctgcaaag ccataagcaa cccaaagtag
     1021 aacctgacta gagatcatta ttccagcgaa aataattaag cactcaaacg ccccatctcg
     1081 ctgccataca ttccatccat gatggaaaag gatgatgcca aagagtagca ccgctttaac
     1141 tgcaaaaaat aacaatccca gaaaaacgat gcgttcaaag cctatgcgaa aattttgtat
     1201 agtcatatca tccaccaaat aagcgtttcc aaaagccatt attccgctta gcttccagct
     1261 ctgctttcac ttttttcagt tcctgagccg ctgcatcacg ctcattttgc aacccggtca
     1321 cctgttcccg cagccggtcg gcctcctgct tatcctcaag caataattgt tgcttctcga
     1381 tcagcttcct cagctcgacc agctcccgct gcattgccaa tattgtatcg tcatcacgtt
     1441 tagtttgtga ccgtgtaacg gcgtttattt tttcctctgg caaggataca gatccgtaat
     1501 gcctgattaa ctcggacaca tcgacgtatc gtttaccttg ctgacgggta acactcacaa
     1561 aacccttatc aatatgggag taaagcgttt ttcttgtgat acctacagcc tcagcagcct
     1621 gtgtaagatt gagtagattt tggctctgtt tactcactgt atacccgtca taaaatagat
     1681 gtgtttactc tgcatagtat acagaaaaat agccaacctg tagatgcgaa agtttctcat
     1741 ctgtgataaa ataggaactg accaataaaa cacacaaaac aggagaaata ttgacctcaa
     1801 cacccatgct gccaacattt gcagcaccta cagatgagga acgcgacacc ctctccgcga
     1861 tcctgaatga caacggcctc cgcgccacta ctccaagaat taacgttctt cactttctga
     1921 atatcgcaga tgtaccagtg acagcagagg cagtcagccg ctgcgttgac ctgccgctat
     1981 cgactgcgta caggacgctc acggtgctgg aagtcaccca ccttgccgga gtgaccttcg
     2041 cgcgtggtga tgtcacacgc tggttcaggt ttacaccgga tacaccgcaa cattgcccgg
     2101 cctgcgggca gagtttttac ggcgaatacg cctgaccgcc tgatacacaa acaccgaaaa
     2161 gatgaccgaa cctaacggtc acaccaaatg acgctcacca cagagcgcca gcggcctgct
     2221 acggcctcta ttcaacgatt acggagacaa ctatgactac aaaaagacag gctcagagag
     2281 ccactgagag cgatttacag gcattcatga acgatgccgc cgaccggttc aaaccagacg
     2341 ccgccgtgct ggccgcgcgg atcgataccg ccgtacaacg ttacttcgta acgagcacca
     2401 cacaacgttt caacgccccg gcaccactgg caatgcagca actacaggaa cgaatccttg
     2461 aaggttggag gtacgatatc ggcatcccgc agtcggtcta tctcgccggt acgggaaaca
     2521 tgagtatcac gcttcgcaaa ccggctgagc tggtggagca ggagatcacc gacctgaaac
     2581 ggcaggttga agattcatac cacaacgagc tggccgccgc catcgagaga gaagtggaca
     2641 agctggtaca ggacgcagca gacgaagccc aacgccgtgc agaggaagcc gcagccgcag
     2701 aacgcgatgc catgcgccag cgtctcaagg atatgctgct gaccggggcg acagcatgac
     2761 agttaccaag gtaaaaagtg ggccaccagc gcccgcacat atcgatcctg acgcactgga
     2821 gcgagctatt gccgccgctc gtaaaatcaa agaggccaac ccggatcgct acaaatcgct
     2881 gcccgtccag ccggaggtta aacaatgaaa atttacgata tcacagtgac gggaacaacc
     2941 gccgactggc tcaccgccac gcgcgggaat atgcccttgc cggtgttcgt ccgcaggctg
     3001 ctgactgaga tcgccagcaa tccggaaaaa tataacgacc tgacccaaac ccttaacgac
     3061 tcagtggagt gcaaatgcca aacccgaaca acgaaaaaat aattgataac gccgccaatg
     3121 attccgatgg gatctccatc gatgaaaaaa acggacatga gcgactggca caccagtttg
     3181 cggaatacct gattaaccag ggcttcatct atctgtcccg gaaaaatggc gcagacctgt
     3241 acagcacgtt gacaggtaaa ttccatccgt tccacgcgga gactaacctc tatcagcagt
     3301 ggctgcgaaa acagtcagag cacagacgta gtggtcacaa tcccctgtta cacgatattc
     3361 tccgccagcg gattaaatac gcatcggcgc gtgagtttat ccccggaggc gctcgccctc
     3421 tggtatacga ggcggacggt gtacccgtac tgaatacctg gaagccatac gaaccacaga
     3481 caaccgccgc agccggtgct gatttgtcac tctgggttga atatctggag cgcctgttcc
     3541 cggacgctga cgagcggcac accgttgtgc aatggctggc gcatatgttc cagcacccgg
     3601 aggttaaacc ctcatggcac ctcatgctga cgagtgcgac cggcacaggg aagggattcc
     3661 tgttcgatca ggttctctca cctctgctat gcgggcaggc atcgttactc agttcgtatg
     3721 acaaactgac cggtcagttc agcactgtga tcgccaataa tttgctggtg tttctggacg
     3781 attgccgcag tagctcaaaa tcgctgcata cccggttgaa atccctgctg acagagcgcc
     3841 gccagcagat cgaggagaag caggagcagg cccggatggt ctcaacctat acccggttta
     3901 tcctcgccag caacgagcga cgcccgatcc gcttttcacc gaacgagcgc gagcgccgtt
     3961 ggttcgtcgt ccggttcatg gagcatcgcc ataacccagt ggagaccggc gaatttatcg
     4021 gtcgattagc acaatggcta acgcaggatg gcagcctcga tgccatttac tggtggttga
     4081 tggcctgtga cctgactgga ttcaacccgc atcattgctg tgcgactgag acactggcgg
     4141 agatgcagga acaatcgcga tccatgctgg atatcgagtt atccgactgg ctggagtcaa
     4201 accgggtatt caaaatggaa acggtacgcc tgctgtttga tgcaccgcca gacctgatta
     4261 agcacaggct ggaggaactt ggatatcgac aagcgccaat caatactaat ggtgctggtg
     4321 ttgaccgttc ccgctactgg ttcccggcag actggaagcc caaacaggcg gcgcagtggc
     4381 tggaggatgc agcagacggt acgacagagc aattctgaca gggagctata cgctcccttt
     4441 tttgcatcca tcagtcgaaa aatcccaaat aatcccaccc atacagcaaa taatcccacg
     4501 ataatcccag caataaaatc aacaaaatac ttataaatca atatttaaag taaataatcc
     4561 caataatccc agcaatccag cgacattatt tatatacaac gtagttactg tggcgcacgc
     4621 cagtaagcta cagggcagcc gtaggcaaag cgaagcgccg tgtgcagatc ctaaagcggc
     4681 ggctctgttc ctggctcagg gacaaagacg gtgctggtgg agaaatgcat atgcaacgca
     4741 ggatcgctta acaaggttcg actccaccgg gccagcctta cgcacacgaa aaatttctac
     4801 aaggcatatt cccatgacag atttgtcgcc agcaggcaca ccaacgccca cagcgatcca
     4861 cgcaccgccg gttttctcac attaaatata cttaaacgtt tgttatttaa taaaaaataa
     4921 atcccagcac atcggcgagg ctaatttata cgatacaggg agtacgtcta caggtcacat
     4981 tgccgatctg tctggtggag tgggaaaccg gctctcgacc cggctcactg ccgcaggtgt
     5041 ccaacgttta ccgcgccggg tagtgatccc gcgctcattt aaataattag cgatagcctg
     5101 gagagtggta tggccgcgtg tccgggctgc gagaatatta tcctcgacgg tcgccgcgaa
     5161 agcatcggcc cgaacggctc tgaccttgat actacgctga cggtttaccc cactggcgtg
     5221 tgcagccgca atattgtcac tccacgtttg caccttttgt tgtgacagtt catcacccgc
     5281 cgcagccctc gcctttaacg acgccagcgc atcactggta cgctgtttga taaagtcccg
     5341 ctcctgttca gctaacgccg catacaaatg gagttgaaac ttatctgccg tgggcatagt
     5401 ggcaacttta atgcagggca actgctctac cagtgtggcg atatccaaca ccgaccgact
     5461 caggcgatcc agtttagcca ccagcaaaca cgccccagtg cgcttacaca actctatggc
     5521 ctggcgcagt ccattacgtt gcattggttc cagcgaacca ctgaccccct catcggtgaa
     5581 ctcatcaatg atctcccaac catgttggcg gacagcgtga gcgatgtagt cagtctgagc
     5641 ctcaagcccc aaaccagagc gcccctgacg ctcagtggat acccgacgat acgtaacaac
     5701 ctgcatattc acccctccaa aaggatcgtg aacgaactgt atcataaatt taccgaacgg
     5761 caaacaaatg ataaaaaaca cagaaagaac ataattaatt gatttatagc aagatatttg
     5821 aaaatcacta tcgataactt ttatcatcca gcgacaccgg tcaggcagat ctccaagtgc
     5881 gccagccgta caatcaccgg caggatattt gcagccagcc ggtttacata tggtgggggg
     5941 gtatcagcga tccagccgca gggggcgggg tgtatctgcc cagcgacatg ggggtcagaa
     6001 tatgcagtta gaatataggg tctctttagt cggtgatttc aagaaaccca gacaccgcaa
     6061 gggatagcgg ggagatcgag aaaagttagt atataggtac caccaaaatg ttggttgcaa
     6121 atctacatca cactacctac aattgcttta aggatgcagc agactggtaa taccagacat
     6181 cccactacca acagcaatgt tggtcgaggc caagcccggt aaaggtgttc tgaataccag
     6241 aagaaatttc tggcgaagcc cgcgactaag cgggctttgt tacatatggg gtttaggtaa
     6301 tggctgcccg cgtagaagat tgtgggcaat cttgaaaaag ctgaccggct tacctgacgg
     6361 tcgctcgctg acgggataag cgctggtgac atggaggcgc agctttttac gctcccgata
     6421 aactctaaaa ggcacaaagt agaactcact ttccccttca tccactgtaa tctctacaac
     6481 agcataacta ccatagccag catggataac cttcgcgtta cccaatcctt caatg
//
