LOCUS       NZ_CP122514            26284 bp    DNA     linear   CON 20-JUN-2024
DEFINITION  Escherichia coli strain W444 plasmid unnamed7.
ACCESSION   NZ_CP122514
VERSION     NZ_CP122514.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN34133716
            Assembly: GCF_030168755.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26284)
  AUTHORS   Yang,J.
  TITLE     Genomic insights into global blaCTX-M-55-positive Escherichia coli
            epidemiology and transmission characteristics
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26284)
  AUTHORS   Yang,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2023) Veterinary college, South China Agricultural
            University, Wushan, Guangzhou, Guangdong 510000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. Version 10.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10X
            Sequencing Technology             :: Illumina HiSeq 2500
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030168755.1-RS_2024_06_20
            Annotation Date                   :: 06/20/2024 05:37:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,474
            CDSs (total)                      :: 5,348
            Genes (coding)                    :: 5,033
            CDSs (with protein)               :: 5,033
            Genes (RNA)                       :: 126
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 315
            CDSs (without protein)            :: 315
            Pseudo Genes (ambiguous residues) :: 0 of 315
            Pseudo Genes (frameshifted)       :: 92 of 315
            Pseudo Genes (incomplete)         :: 217 of 315
            Pseudo Genes (internal stop)      :: 58 of 315
            Pseudo Genes (multiple problems)  :: 46 of 315
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP122514.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..26284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="W444"
                     /host="pig"
                     /db_xref="taxon:562"
                     /plasmid="unnamed7"
                     /geo_loc_name="China:Guangdong"
                     /collection_date="2009"
     gene            140..970
                     /locus_tag="QC806_RS27130"
     CDS             140..970
                     /locus_tag="QC806_RS27130"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /protein_id="WP_001334766.1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFL
                     LYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEI
                     WNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAW
                     LESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTA
                     NRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL"
                     /name="oxacillin-hydrolyzing class D beta-lactamase OXA-1"
     gene            1108..1740
                     /locus_tag="QC806_RS27135"
     CDS             1108..1740
                     /locus_tag="QC806_RS27135"
                     /EC_number="2.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B-3 chloramphenicol O-acetyltransferase
                     CatB3"
                     /protein_id="WP_000186237.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCAR
                     YLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSALDA
                     FQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVEPYAIVGGNPAKKIKK
                     RFTDEEISLLLEMEWWNWSLEKIKAAMPMLCSSNIVGLHKYWLEFAV"
                     /name="type B-3 chloramphenicol O-acetyltransferase CatB3"
     gene            1825..2277
                     /gene="arr"
                     /locus_tag="QC806_RS27140"
     CDS             1825..2277
                     /gene="arr"
                     /locus_tag="QC806_RS27140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)--rifampin ADP-ribosyltransferase"
                     /protein_id="WP_104773092.1"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISNFEDG
                     RILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGNPT
                     QSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
                     /name="arr"
     gene            2500..2847
                     /locus_tag="QC806_RS27145"
     CDS             2500..2847
                     /locus_tag="QC806_RS27145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            2841..>2999
                     /locus_tag="QC806_RS27150"
                     /pseudo=""
     CDS             2841..>2999
                     /locus_tag="QC806_RS27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019727244.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /name="dihydropteroate synthase"
     gene            <3000..3209
                     /locus_tag="QC806_RS27155"
                     /pseudo=""
     CDS             <3000..3209
                     /locus_tag="QC806_RS27155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            3669..3764
                     /gene="dqlB"
                     /locus_tag="QC806_RS27160"
     CDS             3669..3764
                     /gene="dqlB"
                     /locus_tag="QC806_RS27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609146.1"
                     /translation="MINLLIIVLRAVAALANALIAVLELIRQFID"
                     /name="dqlB"
     gene            3831..4010
                     /locus_tag="QC806_RS27165"
     CDS             3831..4010
                     /locus_tag="QC806_RS27165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000347021.1"
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFPGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
                     /name="hypothetical protein"
     gene            complement(4126..4770)
                     /locus_tag="QC806_RS27170"
     CDS             complement(4126..4770)
                     /locus_tag="QC806_RS27170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000203199.1"
                     /translation="MTSNAPTNFVRAYLRASTAEQDASRALETIEAFARERGLIICSYY
                     IENESGSRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISSAIKRKSLQSSGE"
                     /name="recombinase family protein"
     gene            5065..5685
                     /locus_tag="QC806_RS27175"
     CDS             5065..5685
                     /locus_tag="QC806_RS27175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864791.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000864788.1"
                     /translation="MKVISFLNPKGGSGKTTAVINIATALSRSGYNIAVVDTDPQMSLT
                     NWSKAGKAAFDVFTAASEKDVYGIRKDLADYDFAIVDGAGSLSVITSAAVMVSDLVIIP
                     VTPSPLDFSAAGSVVTVLEAQAYSRKVEARFLITRKIEMATMLNVLKESIKDTGVKAFR
                     TAITQRQVYVKSILDGDSVFESSDGAAKGEIEILTKEIVRMFE"
                     /name="ParA family protein"
     gene            5737..5967
                     /locus_tag="QC806_RS27180"
     CDS             5737..5967
                     /locus_tag="QC806_RS27180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_000051066.1"
                     /translation="MSLEKAHTSVKKMTFGENRDLERVVTAPVSSGKIKRVNVNFDEEK
                     HTRFKAACARKGTSITDVVNQLVDNWLKENE"
                     /name="plasmid partition protein ParG"
     gene            6391..7455
                     /locus_tag="QC806_RS27185"
     CDS             6391..7455
                     /locus_tag="QC806_RS27185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849600.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_012291478.1"
                     /translation="MKTISLFNNKGGVGKTTLTWNLSVSLSAKGKSVLLIDFDPQCNLS
                     IALLGETGFSDLLKKDANNPYGKTIRAFCQPFIQQDILPVVHTFPPQFPMEPGSGRLDI
                     APGDFWLNNLSDVISVGTDLIAGNAVNRFLIPSLIASKAQELNNCEYDYVLIDVPPSFN
                     TIVRSALYCSDYFLVPCTADIFSAYCIGLIGETLPKFRDDWEQGIRRTSAQNNSLISQK
                     GSPKFAGWVFNGFDKRKNPGQQNSSEIAADAAHRDKIIDSVKNDLRPKLASIKTYSAVA
                     SFTPDTPVAKVEDLNVMAPDSILQGVPLRYLSTVAPTRGVLARGAWSGPQKALMQTMSA
                     EHDVLADYIIQNFV"
                     /name="ParA family protein"
     gene            complement(7993..8346)
                     /gene="ddp1"
                     /locus_tag="QC806_RS27190"
     CDS             complement(7993..8346)
                     /gene="ddp1"
                     /locus_tag="QC806_RS27190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_024129958.1"
                     /translation="MKYLVKEFINEKYSKAVNILKDNLKEHYHVFYGVRLSEILFPTSE
                     YGTDAFFKEFELINSVILPLVIFDFIDRKPIMVIGFEEAPGIDSLIDSGMEVVLLDGLS
                     DLLLVEKLMPLFD"
                     /name="ddp1"
     gene            complement(8483..8929)
                     /locus_tag="QC806_RS27195"
     CDS             complement(8483..8929)
                     /locus_tag="QC806_RS27195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001074384.1"
                     /translation="MAKIYQFPQGEERAKFRKEIARERKKRFAVKTGSTFVKWLGWGWF
                     YLRLLAASVLHFIFVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWILGLLAEPLMELLNKTMPWHKLLVPEPADESTENSSEISQQ"
                     /name="hypothetical protein"
     gene            complement(8933..9775)
                     /locus_tag="QC806_RS27200"
     CDS             complement(8933..9775)
                     /locus_tag="QC806_RS27200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435061.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000435064.1"
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLEVLEINETLHIR
                     RKTESGALATKACPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRVFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVERSVAYKQMKDAADFFSRNKNLITHCDYISNEGLLR
                     VMFSSKTINYITAIDSRKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
                     /name="replication initiation protein"
     gene            complement(9796..10635)
                     /locus_tag="QC806_RS27205"
     CDS             complement(9796..10635)
                     /locus_tag="QC806_RS27205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722379.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_024129959.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVKRVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
                     /name="replication initiation protein"
     gene            11870..12121
                     /locus_tag="QC806_RS27210"
     CDS             11870..12121
                     /locus_tag="QC806_RS27210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            12111..12392
                     /locus_tag="QC806_RS27215"
     CDS             12111..12392
                     /locus_tag="QC806_RS27215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_284632255.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRALGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADMR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(12631..>12723)
                     /locus_tag="QC806_RS27220"
                     /pseudo=""
     CDS             complement(12631..>12723)
                     /locus_tag="QC806_RS27220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(<12995..14080)
                     /locus_tag="QC806_RS27225"
                     /pseudo=""
     CDS             complement(<12995..14080)
                     /locus_tag="QC806_RS27225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858395.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(14090..14278)
                     /locus_tag="QC806_RS27230"
     CDS             complement(14090..14278)
                     /locus_tag="QC806_RS27230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000957857.1"
                     /translation="MLTRKSIDTVLLSVGAEKLSQREWDWMKMLKPMDPPPAMVTTSIL
                     KRRGDTAALTLLQDTGV"
                     /name="hypothetical protein"
     gene            14398..15828
                     /locus_tag="QC806_RS27235"
                     /pseudo=""
     CDS             14398..15828
                     /locus_tag="QC806_RS27235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041207141.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS50R family transposase"
                     /name="IS4-like element IS50R family transposase"
     gene            15857..16651
                     /locus_tag="QC806_RS27240"
     CDS             15857..16651
                     /locus_tag="QC806_RS27240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3')-IIa"
                     /protein_id="WP_000572405.1"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKARMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
                     /name="aminoglycoside O-phosphotransferase APH(3')-IIa"
     gene            16799..17503
                     /locus_tag="QC806_RS27245"
     CDS             16799..17503
                     /locus_tag="QC806_RS27245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067858.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            18214..18870
                     /locus_tag="QC806_RS27250"
     CDS             18214..18870
                     /locus_tag="QC806_RS27250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS2"
                     /protein_id="WP_012537714.1"
                     /translation="METYRHTYRHHSFSHQDLSDITFTACTFIRCDFRRANLRDATFIN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIELRECDLKGANFSRANF
                     ANQVSNRMYFCSAFITGCNLSYANMERVCLEKCELFENRWIGTHLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIASWQQEQLLEALGIVVFPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS2"
     gene            19154..19813
                     /locus_tag="QC806_RS27255"
     CDS             19154..19813
                     /locus_tag="QC806_RS27255"
                     /inference="COORDINATES: protein motif:HMM:NF021759.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="WP_077898834.1"
                     /translation="MPLLHLQREKQTYGYFSPERFVNSQGTRTDEIAMNPAYFAVCPPE
                     EIMQTLCHEMCHLWQHHFGKPGRRGYHNKEWADFMEAIGLMPSSTGAPGGARTGDKMAD
                     YAIEGGRFLEAYESLMTDDYRISWMDRFPSREKLMAAIANGTTDEMAGDLSIMGLAGIS
                     VEDGEITFEPGERPNKSNREKWHCCKVSDEAAFCLIQRPYISKTLLTRRISPRGSP"
                     /name="SprT-like domain-containing protein"
     gene            complement(19759..20463)
                     /locus_tag="QC806_RS27260"
     CDS             complement(19759..20463)
                     /locus_tag="QC806_RS27260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            20573..20800
                     /locus_tag="QC806_RS27265"
     CDS             20573..20800
                     /locus_tag="QC806_RS27265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000335894.1"
                     /translation="MCMAGKLTGDSGGSECNSAEAAFFNIVKKNKHGFLPNHTKDARKA
                     FLNECPDNGEGGSNQSMISQIISKYGKVRL"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            20836..21147
                     /locus_tag="QC806_RS27270"
     CDS             20836..21147
                     /locus_tag="QC806_RS27270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001452736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001452736.1"
                     /translation="MKKIILSALACTALLTGCVSQDKGNAMQSQLNNQQRQINELSVRL
                     QSAESRLSKQEEKLRNELLQSSGYCYLNGARYSTGTVLYGRICQNQSGSASWQVYSRR"
                     /name="hypothetical protein"
     gene            21335..21883
                     /locus_tag="QC806_RS27275"
     CDS             21335..21883
                     /locus_tag="QC806_RS27275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000893479.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_235842573.1"
                     /translation="MLERIKTLPGFPQKINYLRKIDPFVFEELLLEGFEAHGFRTIRNK
                     RYTGDGGIDGQVIIGKYRYLIQAKRYRGHIALQHVQEFEKLLKRHNCRGLFCHTGKTGA
                     GSKSVSIASERMEIISGQRLIDLLTPGSSFTIATAPQTMMKRTAATLETSTIVKDAGRG
                     RLRKRKIKHAKPVAAVAMA"
                     /name="restriction endonuclease"
     gene            complement(21852..>22706)
                     /locus_tag="QC806_RS27280"
                     /pseudo=""
     CDS             complement(21852..>22706)
                     /locus_tag="QC806_RS27280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021138877.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            22902..23294
                     /locus_tag="QC806_RS27285"
     CDS             22902..23294
                     /locus_tag="QC806_RS27285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_000084745.1"
                     /translation="MSQVVDFLNEAKTFYFATVEGDQPRVRPFNAAMERNGKVYLGTTN
                     QKKVYQQLLANSKVEVSGMAKGKWIRLTGEAVIDDTVEAREAMLEANPPLRDWYSADDG
                     KFTVFYLKNMQAVLYSFTGDPEILDN"
                     /name="pyridoxamine 5'-phosphate oxidase family protein"
     gene            23409..>23976
                     /locus_tag="QC806_RS27290"
                     /pseudo=""
     CDS             23409..>23976
                     /locus_tag="QC806_RS27290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            24009..>24407
                     /locus_tag="QC806_RS27295"
                     /pseudo=""
     CDS             24009..>24407
                     /locus_tag="QC806_RS27295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /name="IS4 family transposase"
     gene            complement(24443..24795)
                     /locus_tag="QC806_RS27300"
                     /pseudo=""
     CDS             complement(24443..24795)
                     /locus_tag="QC806_RS27300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621591.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /name="VOC family protein"
     gene            complement(25017..>25226)
                     /locus_tag="QC806_RS27305"
                     /pseudo=""
     CDS             complement(25017..>25226)
                     /locus_tag="QC806_RS27305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            <25224..25433
                     /locus_tag="QC806_RS27310"
                     /pseudo=""
     CDS             <25224..25433
                     /locus_tag="QC806_RS27310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            26049..26144
                     /gene="dqlB"
                     /locus_tag="QC806_RS27315"
     CDS             26049..26144
                     /gene="dqlB"
                     /locus_tag="QC806_RS27315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609146.1"
                     /translation="MINLLIIVLRAVAALANALIAVLELIRQFID"
                     /name="dqlB"
     ARG             18215..18867
                     /name="qnrS2"
                     /gene="qnrS2"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS2"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2501..2844
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1826..2274
                     /name="arr-3"
                     /gene="arr-3"
                     /gene_name="NAD(+)--rifampin ADP-ribosyltransferase Arr-3"
                     /tool="amrfinderplus"
                     /drug_class="RIFAMYCIN"
                     /identity="99.33"
                     /coverage="100.0"
     ARG             15858..16648
                     /name="aph(3')-IIa"
                     /gene="aph(3')-IIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             141..967
                     /name="blaOXA-1"
                     /gene="blaOXA-1"
                     /gene_name="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1109..1737
                     /name="catB3"
                     /gene="catB3"
                     /gene_name="type B-3 chloramphenicol O-acetyltransferase
                     CatB3"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2842..3209
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="43.73"
     Typing          complement(8484..8929)
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gatgcctaac ccttccatcg agggggacgt ccaagggctg gcgcccttgg ccgcccctca
       61 tgtcaaacgt tgggcgaacc cggagcctca ttaattgtta gccgttaaaa ttaagccctt
      121 taccaaacca atacttatta tgaaaaacac aatacatatc aacttcgcta tttttttaat
      181 aattgcaaat attatctaca gcagcgccag tgcatcaaca gatatctcta ctgttgcatc
      241 tccattattt gaaggaactg aaggttgttt tttactttac gatgcatcca caaacgctga
      301 aattgctcaa ttcaataaag caaagtgtgc aacgcaaatg gcaccagatt caactttcaa
      361 gatcgcatta tcacttatgg catttgatgc ggaaataata gatcagaaaa ccatattcaa
      421 atgggataaa acccccaaag gaatggagat ctggaacagc aatcatacac caaagacgtg
      481 gatgcaattt tctgttgttt gggtttcgca agaaataacc caaaaaattg gattaaataa
      541 aatcaagaat tatctcaaag attttgatta tggaaatcaa gacttctctg gagataaaga
      601 aagaaacaac ggattaacag aagcatggct cgaaagtagc ttaaaaattt caccagaaga
      661 acaaattcaa ttcctgcgta aaattattaa tcacaatctc ccagttaaaa actcagccat
      721 agaaaacacc atagagaaca tgtatctaca agatctggat aatagtacaa aactgtatgg
      781 gaaaactggt gcaggattca cagcaaatag aaccttacaa aacggatggt ttgaagggtt
      841 tattataagc aaatcaggac ataaatatgt ttttgtgtcc gcacttacag gaaacttggg
      901 gtcgaattta acatcaagca taaaagccaa gaaaaatgcg atcaccattc taaacacact
      961 aaatttataa aaaatctaat ggcaaaatcg cccaaccctt caatcaagtc gggacggcca
     1021 aaagcaagct tttggctccc ctcgctggcg ctcggcgccc cttatttcaa acgttagacg
     1081 gcaaagtcac agaccgcggg atctcttatg accaactact ttgatagccc cttcaaaggc
     1141 aagctgcttt ctgagcaagt gaagaacccc aatatcaaag ttgggcggta cagctattac
     1201 tctggctact atcatgggca ctcattcgat gactgcgcac ggtatctgtt tccggaccgt
     1261 gatgacgttg ataagttgat catcggtagt ttctgctcta tcgggagtgg ggcttccttt
     1321 atcatggctg gcaatcaggg gcatcggtac gactgggcat catctttccc gttcttttat
     1381 atgcaggaag aacctgcatt ctcaagcgca ctcgatgcct tccaaaaagc aggtaatact
     1441 gtcattggca atgacgtttg gatcggctct gaggcaatgg tcatgcccgg aatcaagatc
     1501 gggcacggtg cggtgatagg cagccgctcg ttggtgacaa aagatgtgga gccttacgct
     1561 atcgttggcg gcaatcccgc taagaagatt aagaaacgct tcaccgatga ggaaatttca
     1621 ttgcttctgg agatggagtg gtggaattgg tcactggaga agatcaaagc ggcaatgccc
     1681 atgctgtgct cgtctaatat tgttggcctg cacaagtatt ggctcgagtt tgccgtctaa
     1741 caattcaatc aagccgatgc cgcttcgcgg cacggcttat ttcaggcgtt atgcagccaa
     1801 atcccaacaa ttaagggtct taaaatggta aaagattgga ttcccatctc tcatgataat
     1861 tacaagcagg tgcaaggacc gttctatcat ggaaccaaag ccaatttggc gattggtgac
     1921 ttgctaacca cagggttcat ctctaatttc gaggacggtc gtattcttaa gcacatctac
     1981 ttttcagcct tgatggagcc agcagtttgg ggagctgaac ttgctatgtc actgtctggc
     2041 ctcgagggtc gcggctacat atacatagtt gagccaacag gaccgttcga agacgatccg
     2101 aatcttacga acaaaagatt tcccggtaat ccaacacagt cctatagaac ctgcgaaccc
     2161 ttgagaattg ttggcgttgt tgaagactgg gaggggcatc ctgttgaatt aataagggga
     2221 atgttggatt cgttggagga cttaaagcgc cgtggtttac acgtcattga agactagtcc
     2281 tttgcataac aaagccatca aaccggacgc cagagattcc gcgcctgttg cgcatggctt
     2341 cgccatttta tgcgcaatag gcgcgccacc ctgtcgccgt ttatggcggc gttagatgca
     2401 ctaagcacat aattgctcac agccaaacta tcaggtcaag tctgctttta ttatttttaa
     2461 gcgtgcataa taagccctac acaaattggg agatatatca tgaaaggctg gctttttctt
     2521 gttatcgcaa tagttggcga agtaatcgca acatccgcat taaaatctag cgagggcttt
     2581 actaagcttg ccccttccgc cgttgtcata atcggttatg gcatcgcatt ttattttctt
     2641 tctctggttc tgaaatccat ccctgtcggt gttgcttatg cagtctggtc gggactcggc
     2701 gtcgtcataa ttacagccat tgcctggttg cttcatgggc aaaagcttga tgcgtggggc
     2761 tttgtaggta tggggctcat aattgctgcc tttttgctcg cccgatcccc atcgtggaag
     2821 tcgctgcgga ggccgacgcc atggtgacgg tgttcggcat tctgaatctc accgaggact
     2881 ccttcttcga tgagagccgg cggctagacc ccgccggcgc tgtcaccgcg gcgatcgaaa
     2941 tgctgcgagt cggatcagac gtcgtggatg tcggaccggc cgccagccat ccggacgcga
     3001 tgacggatgg ctggccgctg tatgaatccc gcctgaaggg aaagctgcac gttatcagca
     3061 agcgttacac tcagcgcatt gagcgacata atctgaatct gagacaacat ctggcaaggc
     3121 tgggacggaa gtcactgtcg ttctcaaaat cggtggagct gcatgacaaa gtcatcgggc
     3181 attatctgaa cataaaacac tatcagtaag ttgggtttgc cgcagaaaat ttattcattt
     3241 aaaatagatc taaatgaagc gggaaactgc agacgtaaaa aaaccgactg gtgaggtcgg
     3301 cttttttaca gttccggtac gagctggtaa ctcgcccgga agagaaactc tctacaactg
     3361 acaacagtat gataatccgt gaagcctgat tatgcaatat gacaggcggt gactacgcgt
     3421 taacggtttg cttgaaagtt agataaacgt ataatcagag ggttagtgct gtggtgagtc
     3481 tttccctgca ttccgctaaa tgcggcatga acagcttcaa agtcctgaca ggtaatacag
     3541 gtggtgctgg ttatctgtgc tctggtagga gtgagactct ctacaactga caagacgaag
     3601 agaagccgtg gtgacaggca gcgtaagagc aagccacggt gtctttactc catttatgga
     3661 gaaaacggat gattaacctg ttaatcatcg ttctgagggc ggtagctgcg cttgcaaacg
     3721 cgctgattgc agttctggaa ctgatccgtc agttcatcga ttgatgactg cggaaacgta
     3781 actaagggca ggaagtgcac cgcttcctgc cctttaacaa aggaggtgtt atggatttta
     3841 tgagcatttt ggggcgctgt ttacttcttc ctttccctgt tgcgatgttt gtcggttgcc
     3901 tgtttccagg catcgatgat cgttttactg gaatgttcat gagttttatt gtcggttgtc
     3961 tatcgtggta tatcaccaag ccaaaaccgc aaaaggctga ggtcgcgtaa gcggcctttt
     4021 attttgatac tcattagtta caacattcaa tttgcttttt aaaaatatcc acttcagcac
     4081 ctccctcata aataacgtca accagtttat tgagctcacc ctaccctact caccggagga
     4141 ttgcagggat ttacgtttta ttgcgctact gattgtgccg cggctgcacc ctagcacctt
     4201 ctgtacctgt gtccaggagc tgccactttc tatcaacctg ataattgcat catgtctggc
     4261 ttgattaggt ttacgccctt tatatttgcc gtctttcctt gctttctcta tcccctgttt
     4321 ctggcgttcg cgccgttgtt catagtccct tctggcaaca gcggccagca tatccagcag
     4381 catatcgtta atggctgcaa acaaccggct gtcaaactca ctcataccag aattaatcca
     4441 ggtcgtcggc acattcacgg ccataacccg gatatctttc tgacggatca ttttcttcag
     4501 cgtattccag tcttcccctg acagtcggga aagtctgtcc acatcctcga taagcaaaat
     4561 gtcattttgc tggcaatctc tcagaagacg aaagagttcc gggcggtcaa gacgggagcc
     4621 ggattcattc tcaatataat agctgcaaat gatcaggcct ctttccctgg caaaagcctc
     4681 gatagtttcc agggcacgcg aagcatcctg ttctgctgtt gaagctctca gataagcgcg
     4741 gacaaagttt gttggtgcat ttgaagtcat attacagaac cagttcgcat aaggtcacac
     4801 cactataccc aaaatgaacc agaaagtgga tcgacaggaa aggcacactc taaaagaacc
     4861 aaaaaacaaa taatgagtag atgtgacctt gtcactacac actcataaac tcaaacactc
     4921 atatacacaa gacaactcaa atgagtagat actccttaac tcatatacac ataaactcat
     4981 attaaccttt gctcatacaa agagtatgat aaactcaaaa actcacagga gtaattgagt
     5041 agacacacaa ttgaggattt gagtatgaag gtgatctcat ttctgaatcc gaaagggggt
     5101 tcaggtaaaa caactgccgt aatcaacata gccactgcgt tgagcaggag cggatacaac
     5161 attgctgtgg tagatacaga tccacaaatg agcctgacga actggagcaa agcgggcaag
     5221 gcagcatttg acgtatttac agcagcatct gaaaaagacg tctatggaat ccgaaaagat
     5281 ctggcggact atgactttgc tattgtggac ggggcaggtt cactctcagt aatcacctcc
     5341 gcagccgtca tggtaagcga tctggtaatt atccctgtca cccccagccc tctggatttc
     5401 tccgcagcag gaagcgtcgt tactgttctg gaagcacagg cttacagccg caaagttgaa
     5461 gcccgctttc tgatcacccg taagatagaa atggcaacca tgttgaatgt gcttaaagaa
     5521 agtatcaaag acaccggtgt taaagcattt cgtacagcta ttacacaacg tcaggtttac
     5581 gtgaaatcaa ttcttgatgg cgacagcgtg tttgaatcca gtgatggtgc tgcaaaaggt
     5641 gaaatagaaa tccttacaaa agagatagtt agaatgtttg agtaattaca catttactca
     5701 tataatcaaa taagtataaa aaccggagta gcctgaatgt cacttgaaaa agcgcatacg
     5761 tcagtaaaaa aaatgacctt tggtgaaaac agagatctgg aacgagtagt aacagcacca
     5821 gtatcatctg gaaaaatcaa acgtgttaac gttaattttg atgaagaaaa gcacacccgg
     5881 tttaaggctg catgcgccag gaaaggtaca tcaatcactg acgtggtgaa ccagcttgta
     5941 gataactggc tcaaagagaa cgaataattg gaagccgaag cgaacagaca ggccgacgca
     6001 aaacaactgt tctcaaagca gccctggcta tgtacaacag ccaatagtta cttgattctg
     6061 caaaacttag atgattcagg atttaatcta tcagtaggag ttcggacaaa atggggtccg
     6121 tgggaatttc tgtgataaca cccgctaagc gatttctcac tgaaagaaat cttcagcccc
     6181 tgcagttagt taaagaaaat taaatctata aacctgtaaa tttttgcgtg acaaactctg
     6241 tcggaatgag aaactgtacg gaaacttcaa ttttaaggtt tgtcgtgcat gttgatggtt
     6301 atatacgggt atcaagcaat cgattacgta ttacactatt ctccgatgta gttatttcta
     6361 aacattgaaa atgtctaaga aaggaataaa atgaaaacta tttcactatt taacaacaaa
     6421 ggcggggtag gaaaaacgac cctgacttgg aacttaagtg tatctctatc ggcaaaggga
     6481 aaatctgttt tgctgataga tttcgatcct caatgcaatt tatcaatagc tttacttggt
     6541 gagactggct tctctgacct tttaaagaag gatgcaaata atccttatgg taaaacgata
     6601 agagcatttt gccaaccatt tatacaacaa gatattctcc ctgtcgtaca tacattccca
     6661 ccacaatttc ccatggagcc tggctcagga aggttagaca tagctccagg tgacttttgg
     6721 ctcaataatc tttcagatgt gattagtgta ggtacagatt taattgctgg aaacgcagta
     6781 aacagattct tgatacctag tttaattgct agtaaagctc aagagttaaa taattgtgaa
     6841 tacgattatg ttcttattga tgtaccgccg tcatttaata cgatagtcag atcggctctc
     6901 tactgttctg attatttctt ggttccatgt actgccgata tattttcggc ttactgcata
     6961 ggactcattg gtgaaacttt accaaaattt agagacgact gggaacaggg tattagaaga
     7021 acttcagccc aaaataactc tctaataagc caaaaaggtt cacctaaatt tgcaggttgg
     7081 gtcttcaacg gatttgataa aagaaagaat ccaggccaac aaaactcatc agagatcgcg
     7141 gctgatgcag cccatagaga taaaataatt gattcagtaa aaaatgacct tcgccccaaa
     7201 ttagcatcta taaaaacata ctcagcagtg gcttctttta ctccagacac tcctgtcgca
     7261 aaagttgaag acctaaatgt tatggctcca gatagtatct tacagggggt cccgctcaga
     7321 tatttatcta ccgtagcacc tactaggggg gtgttggcca gaggggcttg gtcaggacct
     7381 cagaaagccc taatgcagac tatgtcggca gaacatgacg ttttagctga ttatataatc
     7441 caaaatttcg tttaatatct tttagggatt gtacgccggc acccctttta ccgtcttagg
     7501 ggttccgtgg gaatttctgc gataacaaac gctaaggaaa agtgaagttc tttagattga
     7561 agcgattagt acgaagtggc ctacataagt gaatggcgaa cagcatacag attctctctt
     7621 aaaaatatgt gagacaatag aaaaacgact gaaaattttt tgtatattaa tagcttcaca
     7681 agctttgatg atagagggta aaaatcacca ttatctaatc aatttgacgc tcatatcatt
     7741 gaatgaagaa acggtaaaaa tcaattgaga gcaatattaa atatcaaaat aaaaacgatg
     7801 aaaaaaagat tgttaccaat acaatgagga cattagaatc acgcccccca aattttatat
     7861 aattaagatc atagatgcag atcagtttgg ttagttctcc gtaggggaga agttatgaaa
     7921 acaggtaaat ggaataaaca tcgttcgtgt aaaatgcatt aatacgaatg ggtaacatgt
     7981 atttccaggg atttaatcaa acaatggcat cagtttttca accagtagca gatcgcttaa
     8041 accatctaac aaaacaactt ccataccaga gtcaataagt gaatcaatcc caggcgcttc
     8101 ctcaaagccg ataaccatga tcggctttcg gtctataaaa tcaaatatta ctaatggaag
     8161 tattacactg ttaattaatt caaattcttt aaagaaagca tctgtgccat attcactggt
     8221 aggaaaaaga atctcactta atctcacacc ataaaaaaca tgatagtgtt ctttaagatt
     8281 atcctttaaa atattaacag ccttagaata tttctcgtta ataaactctt tgaccagata
     8341 tttcataaac atctccaata agaaccgact gtaggtcacc gggcaaacgt tgcggaatgg
     8401 cgtcagagac gtcattttgc ggcgtttgcc ctatcctgca tcgcagtgaa aaggcaggga
     8461 ctggcataac tgctgagtag catcattgct ggcttatctc gctactgttc tcggtgcttt
     8521 cgtccgcagg ttcgggaaca agtaacttgt gccagggcat agttttgttg agcagctcca
     8581 tcagaggctc agccagcagt cccaaaatcc aggttgccgt aatcaccggt atagtcagat
     8641 tttgtggcgt ccataactgg tgatcgagat gataccaggt gatgacacac aaaatacccc
     8701 ccagccagaa cacagcccat ttaaacgcac caagaatggc taacacaaaa acaaagataa
     8761 aatgtaaaac actcgcggca agaagacgaa gataaaacca tccccagcca agccacttaa
     8821 caaaagtgct ccctgttttc actgcaaaac gtttcttacg ctccctggcg atttctttcc
     8881 tgaatttagc tcgttcttcc ccctgaggga attgatagat tttagccatg agttacctca
     8941 tttcgatctc aaaacggact ttgctgactc ttctcccctg cctttcagca ttaacacatt
     9001 taatgttttt aacatctgtc ctttctgtta tttcatcaat agctatattg attccatctc
     9061 ttttaaagaa agaaaacttt tgattttgaa tataacctat ttctttctta agttcatcta
     9121 cacctatagt gaaagattta agatggctaa attttatcag ttgatataaa ggccatgagt
     9181 atcttccttg aagagacaaa gcagatttta gaggaagctc ggtaacctga tatttacggg
     9241 agtctatcgc tgtaatataa tttatcgtct tagacgaaaa cataacacga agcaatccct
     9301 cattcgaaat atagtcacaa tgtgtaatta aatttttatt tcttgaaaag aaatctgctg
     9361 catccttcat ttgcttatat gcaacagaac gctcaacacc aacaaattct gcatacttat
     9421 cagcccggat caatagcgac ttatccgatt caagtttatt ttcaaagtaa taatataaac
     9481 aaataaaaaa gacccttctt gccgaaaatg acagttcatt aactaacaga tttaatccgc
     9541 tattatatct aataatttta tcgtaattaa catgcctcat agtagatgaa aaaagagaag
     9601 gacaagcttt agtagctaaa gctcctgatt ctgtctttct tcttatatga agagtctcat
     9661 ttatttctag tacctccaat aaggttccat cttcccatcc tgtattttct atcatactag
     9721 caggaatgat aattactgcc gcaccacctt gtttatgtaa ttttatttgc tccatagtgt
     9781 atttaccttt atatattaag cacctctgaa accatacggt attctggtat caagtccttc
     9841 gctttcttta tctattttat acgaaaatct tagctttgat gctcttcttg cgactctctt
     9901 aacaatttta acttcgagat gattaatctc tgtatattga tttatttttt caatattttt
     9961 ttgcagaaaa accttattaa aatccttaaa attctgataa aggtaaactt tttcgccatt
    10021 atctattctg aataattcaa gttcatcctt taatacatct acttcaatgt cgaaaaatgt
    10081 ctttttacca ctgctgtatt gtttcctgat aaactgataa agcatatttg aattttgatc
    10141 agcgagtctt acagacgata tcaaaacctg agtagtgtaa gaatccttta acatcgtgat
    10201 atatggctca atgacatgtg aaaaagcaat atcaatatat ccttcacttt caacataatc
    10261 acaaaacgca gtcaggttca taagcctgac tgcatcagaa ggtaatttac ctctcttctt
    10321 cgtatgtcca gagctttgat tgccctgagc tgtgagaagt tgatttcgag gaatacgaat
    10381 aacactggcc tgaagttctt ctgccccctc tttcaactgc cggtaagcac ctgttacatc
    10441 aatatcagcg ataaatgcat attcccgagc cgtaatacga aaggttgccc cctcagataa
    10501 ctcttcacgt gaatcaatct gcgccatagc cataaacaaa attcttctgg cagacaaagg
    10561 caacgatgag aatgtgctgt taatttcatt tctgtggcga atttttgttt tctttgtaac
    10621 gctcagtaag ttcatacatt acctttggtt tttaagttct tatggtgaaa tcataaccac
    10681 aaaggcggaa atatgtaaag tggtttatcc accttatatg tttccaccaa aacacggatc
    10741 acatgaaaga atttttatca tttatattca atatgataga aatgcgcagg tatccacctt
    10801 ttaacgtcat acgttagatt agagcactat aaagaactaa agaaatgaag atacaaagat
    10861 acgaatatct gaataaaaac agaaaaatgc gtacccatcc acctttcagt gcgtacccat
    10921 ccacctttca gtgcgcagcc atccaccttt catgaaaatt acagtgcgta cccatccacc
    10981 tttcagtgcg tacccatcca cctttcattt tgaggcgaca aaaaacaaca cctatcttaa
    11041 tgaaattatt gataaaaaaa ctggcacaat gtttgcagaa taagttagag taagttaaag
    11101 atcttaaagt agatctaccg atctacattt aagatcttaa aaacaagaag tttaataagc
    11161 aaaaaaacac aaaaaatctg tggataactt tgctcaaaac aaaaaattca cactacctgt
    11221 ggataacttt gcgtaaaccc agaggacaga tcactctgaa ccaagacaac cacacataaa
    11281 aacaatatgc tcgcttttta accactgcgc gtaattgcct gatgttatcc ctgtgctgtt
    11341 ccgcttcctc gctcactaac tcgctacact cggtcgttcg gctgcggcga gcggtgtctc
    11401 ctttctcaaa accagaagag ttcagatcat acgatccgtt gattgatcct ttttggatct
    11461 ttcactgaga agccctgaat cgctttctaa cgctttgttc gatgtaacca tgaggaaaac
    11521 catgtgaaat cgaaaaaatc gctcagaatg cgatacagcg cgttttagag ggtatttaca
    11581 aaacagtcgt tgccttgagg aaattttgat caagattgaa ctcctatccg gatcatggca
    11641 acagatcaca gcaacaaggc cgctaaaaag cgttgagcgg cgttaaaaac cgttaaaccg
    11701 tagctgacta taacgaaacg ggaaaaaacg ctcagaacgc gttacagagc gttttaaggc
    11761 gatgtcggaa agagccatac ctcacctgtt ctgatgtttt tctcaacaca agcactttta
    11821 agagtacttt taaagatgct attatgccaa taagacaagc ggaggactta tgagctatca
    11881 aattctgaca accacagcgg ccagtattac tgacctgaaa aaaaatccta tgggaaccgt
    11941 agctgaaggt gaaggggacg ctgttgcgat cctgaaccga aacgaaccgg cgttctattg
    12001 cgttccacca aaactttacg cctactatcg ggaactcgct gaagatgctg agttaaacgc
    12061 tgttgctgat gagcgcatga aaaacccgga aattgtgaag gttaacctgg atgacctatg
    12121 aactggcttt tgaccgcaga gcactgaagg aatggcagaa actcggccac accatccgtg
    12181 aacaattcaa aaagaagctg gcagaacggc tggaaaatcc acgcgtaccc gcagcccggt
    12241 tacatggtca tgctgatcgc tataaaatca aacttcgtgc acttggctac agacttgtat
    12301 atcaagtcat tgatgagaaa gtcgttttac tcgttattgc tgttggaaga agggaaagca
    12361 gcgaagttta tcagattgca gatatgcgct gaactgaaac ccgccccgta attcgcggct
    12421 gcagccgctc agacgcgcag atgctacaca ccgtcacggc gtaccgttcg caagcttacg
    12481 cgctaactgc gaaaggctaa ttgcgtgttg ttagtccggt aatgggcttt gcagggaggg
    12541 gggatgtccc tgatcttaat taagctggtt tgtttccggg cactgttgca aagttagcga
    12601 tgaggcagcc ttttgtctta ttcaaaggcc ttacatttca aaaactctgc ttaccaggcg
    12661 catttcgccc aggggatcac cataataaaa tgctgaggcc tggcctttgc gtagtgcacg
    12721 tataggaaat tgaaaaacca gtcgatacca ttgtccacgc cttatgccac gtgagccttt
    12781 ctgcttttcc caccactccg gtggtttccc tctctgtatg gtcgattttt ataccgtaac
    12841 aggctgtttt ttatactttc accgattccc gggcacttta gcctgatgaa tcaggccgga
    12901 tatacttctt cagtagactg ttgttgcgcg tttttcttca gccctgatac agctttgctg
    12961 caatggcccg gcggagatac catccggcag cccacagcac gcattcgaac gggtcacgac
    13021 tcaggaactg tttcaccatt tgtgccatag acctttcgcc actggttccg gtttatccat
    13081 ccccagtgca cggcacacct cggcagctta cgccagtaca cggttggcaa cccgaagttt
    13141 tcaccatctt caaaaacgct ccgggtatgt gctgtttcag cctcgcgacc agctcacgct
    13201 gtgtcagcgt ttccgtcgcc gtttctcccg ttttgtggtc cgtaacggaa gctcaggctt
    13261 gccctccgtt gtaatgagcc agtcgggaag ccgctattgg tggcttcttc agataacgag
    13321 ccagctatag cgtgccgtat tccgccctcc ggctgtcttc ttcgacatgt acaatgccag
    13381 tattttccgc cggatttcag caccgaaggc ttctccactg tgattccgtc gtgattgaca
    13441 acgactcctt tttgccatcc ctctgaccac gctttcagaa gcagctgccg catattccac
    13501 atccaccgtg aacgcatcgc gtctttcagg aagctcagct ttttccactg accatgctta
    13561 ttcagacctc cacaggttac agacacatgt acatgcggat gccagttgag acgacggcca
    13621 tacgtgtgga tggcgcagaa gataccgggt tccagccccg ttttcgggcg gcatacagca
    13681 gattctccac cgccagacgg cacacgtcat tcagcagcca gcggttgctt tcggccgaac
    13741 accggccaca gcgtgtccgg cagggtgaag accagatgta cccagtcgca gtcaggaaga
    13801 cgattcagct gtgttgctgt ccacaggtct gtggccttct ttccgcagga cggcaggcac
    13861 ggctgccgca tgagttggtc aggtaaaact ttacgtgctg acagtccggg ttatcacacc
    13921 cgaactcttt tacacccagt atccgtgtgc cgcaggccag cattttggtg acggcttcaa
    13981 cctcgatatc gcgcagaccg cccgcatcca ggaaggacgt ccagcactgg ttggctgtga
    14041 acagacgttt cagagggcgg ggagtaaaac cggacaacat gaggatggat taaaccccgg
    14101 tatcctgtag cagggtaagg gctgctgtat cgccacggcg cttcaggatg gaggtcgtca
    14161 ccatcgcagg tggtgggtcc atgggtttga gcattttcat ccagtcccat tctcgttgtg
    14221 agagcttctc agcaccaaca gagagcagaa ctgtatcgat acttttgcgg gtcaacataa
    14281 ggggatgagt ccttaataaa acaggtcctc agagcataca tattctgcgg ggcgtgcggc
    14341 aacaacagga cgaaccgggg cggttttcaa tttgcagccg ccaggctgcc gtggttcatg
    14401 ataacttctg ctcttcatcg tgcggccgac tgggctaaat ctgtgttctc ttcggcggcg
    14461 ctgggtgatc ctcgccgtac tgcccgcttg gttaacgtcg ccgcccaatt ggcaaaatat
    14521 tctggtaaat caataaccat ctcatcagag ggtagtgaag ccatgcagga aggcgcttac
    14581 cgatttatcc gcaatcccaa cgtttctgcc gaggcgatca gaaaggctgg cgccatgcaa
    14641 acagtcaagt tggctcagga gtttcccgaa ctgctggcca ttgaggacac cacctctttg
    14701 agttatcgcc accaggtcgc cgaagagctt ggcaagctgg gctctattca ggataaatcc
    14761 cgcggatggt gggttcactc cgttctcttg ctcgaggcca ccacattccg caccgtagga
    14821 ttactgcatc aggagtggtg gatgcgcccg gatgaccctg ccgatgcgga tgaaaaggag
    14881 agtggcaaat ggctggcagc ggccgcaact agccggttac gcatgggcag catgatgagc
    14941 aacgtgattg cggtctgtga ccgcgaagcc gatattcatg cttatctgca ggacaaactg
    15001 gcgcataacg agcgcttcgt ggtgcgctcc aagcacccac gcaaggacgt agagtctggg
    15061 ttgtatctgt acgaccatct gaagaaccaa ccggagttgg gtggctatca gatcagcatt
    15121 ccgcaaaagg gcgtggtgga taaacgcggt aaacgtaaaa atcgaccagc ccgcaaggcg
    15181 agcttgagcc tgcgcagtgg gcgcatcacg ctaaaacagg ggaatatcac gctcaacgcg
    15241 gtgctggccg aggagattaa cccgcccaag ggtgagaccc cgttgaaatg gttgttgctg
    15301 accagcgaac cggtcgagtc gctagcccaa gccttgcgcg tcatcgacat ttatacccat
    15361 cgctggcgga tcgaggagtt ccataaggca tggaaaaccg gagcaggagc cgagaggcaa
    15421 cgcatggagg agccggataa tctggagcgg atggtctcga tcctctcgtt tgttgcggtc
    15481 aggctgttac agctcagaga aagcttcacg ctgccgcaag cactcagggc gcaagggctg
    15541 ctaaaggaag cggaacacgt agaaagccag tccgcagaaa cggtgctgac cccggatgaa
    15601 tgtcagctac tgggctatct ggacaaggga aaacgcaagc gcaaagagaa agcaggtagc
    15661 ttgcagtggg cttacatggc gatagctaga ctgggcggtt ttatggacag caagcgaacc
    15721 ggaattgcca gctggggcgc cctctggtaa ggttgggaag ccctgcaaag taaactggat
    15781 ggctttcttg ccgccaagga tctgatggcg caggggatca agatctgatc aagagacagg
    15841 atgaggatcg tttcgcatga ttgaacaaga tggattgcac gcaggttctc cggccgcttg
    15901 ggtggagagg ctattcggct atgactgggc acaacagaca atcggctgct ctgatgccgc
    15961 cgtgttccgg ctgtcagcgc aggggcgccc ggttcttttt gtcaagaccg acctgtccgg
    16021 tgccctgaat gaactgcagg acgaggcagc gcggctatcg tggctggcca cgacgggcgt
    16081 tccttgcgca gctgtgctcg acgttgtcac tgaagcggga agggactggc tgctattggg
    16141 cgaagtgccg gggcaggatc tcctgtcatc tcaccttgct cctgccgaga aagtatccat
    16201 catggctgat gcaatgcggc ggctgcatac gcttgatccg gctacctgcc cattcgacca
    16261 ccaagcgaaa catcgcatcg agcgagcacg tactcggatg gaagccggtc ttgtcgatca
    16321 ggatgatctg gacgaagagc atcaggggct cgcgccagcc gaactgttcg ccaggctcaa
    16381 ggcgcgcatg cccgacggcg aggatctcgt cgtgacccat ggcgatgcct gcttgccgaa
    16441 tatcatggtg gaaaatggcc gcttttctgg attcatcgac tgtggccggc tgggtgtggc
    16501 ggaccgctat caggacatag cgttggctac ccgtgatatt gctgaagagc ttggcggcga
    16561 atgggctgac cgcttcctcg tgctttacgg tatcgccgct cccgattcgc agcgcatcgc
    16621 cttctatcgc cttcttgacg agttcttctg agcgggactc tggggttcga aatgaccgac
    16681 caagcgacgc ccaacctgcc atcacgagat ttcgattcca ccgccgcctt ctatgggcac
    16741 tgttgcaaat agtcggtggt gataaactta tcatcccctt ttgctgatgg agctgcacat
    16801 gaacccattc aaaggccggc attttcagcg tgacatcatt ctgtgggccg tacgctggta
    16861 ctgcaaatac ggcatcagtt accgtgagct gcaggagatg ctggctgaac gcggagtgaa
    16921 tgtcgatcac tccacgattt accgctgggt tcagcgttat gcgcctgaaa tggaaaaacg
    16981 gctgcgctgg tactggcgta acccttccga tctttgcccg tggcacatgg atgaaaccta
    17041 cgtgaaggtc aatggccgct gggcgtatct gtaccgggcc gtcgacagcc ggggccgcac
    17101 tgtcgatttt tatctctcct cccgtcgtaa cagcaaagct gcataccggt ttctgggtaa
    17161 aatcctcaac aacgtgaaga agtggcagat cccacgattc atcaacacgg ataaagcgcc
    17221 cgcctatggt cgcgcgcttg ctctgctcaa acgcgaaggc cggtgcccgt ctgacgttga
    17281 acaccgacag attaagtacc ggaacaacgt gattgaatgc gatcatggca aactgaaacg
    17341 gataatcaac gccacgctgg gatttaaatc catgaagacg gcttacgcca ccatcaaagg
    17401 tattgaggtg atgcgtgcac tacgcaaagg ccaggcctca gcattttatt atggtgatcc
    17461 cctgggcgaa atgcgcctgg taagcagagt ttttgaaatg taaggccttt gaataagaca
    17521 aaaggctgcc tcatcgctaa ctttgcaaca gtgccgtttt gcttactttg gataacgagc
    17581 agaaatcatc cctggtcatt tttagaaatt ccctggcatg gcggcattgt agatttgtaa
    17641 agtcgtgaga ggggctatta tagccttgcc gatttagctt tattcctatg tcggtagtcc
    17701 aactaacggc ggtgggatat gaaattccta acctacttgc taatttatgt aatgtacctt
    17761 cttcctgccc tagttctaac ccccccatgt tttttcgtac gtacgaaatt tttcggtttt
    17821 gcagtggctt ttggccttcg gccaggctca ccaggtcgcg gggctccctg gctcgtcggc
    17881 ttcccctaac tttggattgt gcaatccaaa aggctgccgc ataatggtta tagattgtgc
    17941 aatccaatac acggagcagg gcactagatg aaaccaacat ggcggacatc agtaatctat
    18001 tgggttcctt ttctctgtgg ctttttaagc ggataacttt tttcaatggt gccgcgtact
    18061 ttgaacgtta acatagaggc tcagggcgct attttacccc cttaaaatag gcaaaatgag
    18121 ggtttttaag atcttgattt ttagtgtttt tattttggtg atgtgatgtg gctttgatgg
    18181 tagtgttgcg tccagttcat cataggagtc aacatggaaa cctaccgtca cacatatcga
    18241 caccacagtt tttcacatca agatctaagt gatattactt tcactgcttg cacctttatc
    18301 cgatgcgatt ttcgacgtgc taacttgcgt gatgcgacat ttattaactg caagttcatt
    18361 gaacagggtg atatcgaagg ttgccatttt gatgtcgcag accttcgcga tgcaagtttc
    18421 caacaatgcc agcttgcgat ggcaaacttt agtaacgcca attgctacgg tattgagtta
    18481 cgtgagtgtg atttaaaagg ggccaacttt tcccgagcaa actttgccaa tcaagtgagt
    18541 aatcgtatgt acttttgctc agcctttatt actggatgta acctgtctta tgccaatatg
    18601 gagcgggtct gtttagaaaa atgtgagctg tttgaaaatc gctggatagg gactcacctc
    18661 gcgggcgcat cactgaaaga gtcagactta agtcgaggtg ttttttctga agatgtctgg
    18721 ggacagttta gcctacaggg tgctaattta tgtcacgccg aactcgacgg tttagatcct
    18781 cgaaaagtcg atacatcagg tatcaaaatt gccagctggc aacaagaaca gcttctcgaa
    18841 gcgttgggta ttgttgtttt tcctgactag atgcttacga atacctgctg ataaactata
    18901 cacaacatta atacattttc taattcaaat caccagagct agatcaatac ttctagctca
    18961 ttcttgtcca gaaacgtgtt tgaatggggc caatcaatct gtggatgctc aagacaacca
    19021 gtatgatact ttattactca gttgtagcgt gactcagatt ttgtagtagg aattagtatg
    19081 aatctttatt tctgggtgag tatcatttag aacggtacaa acagggttac ttgactgctt
    19141 agtatgaaac tttattcctc tcctacacct ccaacgagaa aaacaaacct atggctattt
    19201 cagcccggag aggttcgtta actcccaagg aacccggacg gacgaaatcg ccatgaatcc
    19261 ggcttacttc gccgtatgcc cccccgaaga aattatgcaa acgctttgcc acgaaatgtg
    19321 ccacctatgg cagcaccatt tcggcaagcc tgggcggcgt ggctatcaca acaaggaatg
    19381 ggccgacttc atggaagcta tcggactaat gccaagcagc accggcgcac ctggtggagc
    19441 acgaaccggc gacaagatgg cggattatgc cattgagggc gggcgcttct tggaagcata
    19501 tgaaagcctg atgacggatg actatcggat cagttggatg gatcgcttcc ccagtcgtga
    19561 aaagctgatg gcagcaatcg ccaacggcac caccgatgaa atggccgggg atctttctat
    19621 catggggctg gctgggatct ctgttgagga tggagaaatc acatttgagc caggggagcg
    19681 cccgaataag tcgaatcggg aaaaatggca ctgttgcaaa gttagcgatg aggcagcctt
    19741 ttgtcttatt caaaggcctt acatttcaaa aactctgctt accaggcgca tttcgcccag
    19801 gggatcacca taataaaatg ctgaggcctg gcctttgcgt agtgcacgca tcacctcaat
    19861 acctttgatg gtggcgtaag ccgtcttcat ggatttaaat cccagcgtgg cgccgattat
    19921 ccgtttcagt ttgccatgat cgcattcaat cacgttgttc cggtacttaa tctgtcggtg
    19981 ttcaacgtca gacgggcacc ggccttcgcg tttgagcaga gcaagcgcgc gaccataggc
    20041 gggcgcttta tccgtgttga tgaatcgcgg gatctgccac ttcttcacgt tgttgaggat
    20101 tttacccaga aaccggtatg cagctttgct gttacgacgg gaggagagat aaaaatcgac
    20161 agtgcggccc cggctgtcga cggcccggta cagatacgcc cagcggccat tgaccttcac
    20221 gtaggtttca tccatgtgcc acgggcaaag atcggaaggg ttacgccagt accagcgcag
    20281 ccgtttttcc atttcaggcg cataacgctg aacccagcgg taaatcgtgg agtgatcgac
    20341 attcactccg cgttcagcca gcatctcctg cagctcacgg taactgatgc cgtatttgca
    20401 gtaccagcgt acggcccaca gaatgatgtc acgctgaaaa tgccggcctt tgaatgggtt
    20461 catgtgcagc tccatcagca aaaggggatg ataagtttat caccaccgac tatttgcaac
    20521 agtgccgctt tatcttcctg ccagccatgc tgaagatccc tgcaaagtta ttatgtgcat
    20581 ggcgggcaag ctcaccggcg atagcggcgg aagcgagtgt aacagtgctg aagctgcttt
    20641 cttcaatatc gttaaaaaga acaagcacgg ctttttaccc aaccacacga aggatgctag
    20701 gaaggctttt cttaatgaat gcccggataa tggcgaaggt ggaagtaacc agtcgatgat
    20761 aagccagatc ataagtaaat acgggaaagt tcgcttatag gcgaaccagg aataatctca
    20821 atttaaggag ccaacgtgaa aaaaataata ttaagtgcat tagcctgtac agctctctta
    20881 actggttgcg tcagccagga taaaggtaat gcgatgcaga gccagctgaa taaccagcaa
    20941 cgccagatta acgaattatc cgttcgtttg cagtctgcgg agtcccggct atcaaagcag
    21001 gaagaaaagc tgcgcaacga actgctgcaa tccagcggct attgctatct gaatggcgcc
    21061 cgctactcga ccggcaccgt actttacggg cggatttgcc agaatcagtc aggcagcgct
    21121 tcgtggcagg tatacagccg tcgctaaaca tcagggcggt ttaaccgccc ttttctttac
    21181 cctcagaaag cccactataa ccatgatccc cttccccact acagaaaacc ttattctatg
    21241 ggcttgcagc gccatcgtac tgcttgccgt tgtattcttc cggcgttcag tacggcacag
    21301 gcgacacaaa aggaagcagc aaagtgcgcg gcgggtgctg gagcgcataa agacgttgcc
    21361 gggcttccca caaaaaatta actacctgag aaaaattgat ccttttgtgt ttgaagaact
    21421 gttgctggaa ggatttgaag cgcatggctt cagaaccatc agaaacaaac gctataccgg
    21481 cgatggaggc attgacggcc aggtaataat aggaaaatat cgctatctta ttcaggctaa
    21541 acgctatcgc ggccatattg ctttacagca cgtacaggag ttcgagaagt tgcttaaacg
    21601 tcataactgt cgcggtctgt tttgccatac cgggaaaacc ggcgcaggtt caaaatctgt
    21661 cagtattgcc agtgaacgga tggagattat cagcggccag cgcctgatag atttgctcac
    21721 gcccggtagc tccttcacta tcgcaaccgc cccgcagacg atgatgaagc gtaccgcagc
    21781 aacgctagaa acgagcacca ttgttaaaga tgccggtagg ggtcgtctca gaaaacggaa
    21841 aataaagcac gctaagccgg tggcagcggt cgcaatggcc taaacttccc cgcaccgacc
    21901 ttggcgctgc tgcgccatag gtaatcgccg gtcaggttga tgtgctccca ccccagcggc
    21961 gacagatatt gcaacaatgt gtcgtccagc gccgtgccgt tgccacacaa agcactggtg
    22021 gcacgctcca gatataccgt gttccacaac acgatggccg ccgtcaccag attgaggccg
    22081 ctggcccggt agcgctgctg ctcaaaactg cggtcgcgga tttcacccaa tcggtagaag
    22141 aagaccgccc tggccagcgc gttgcgcgcc tcgcccttat tcagccccgc atggacgcgg
    22201 cggcgcagct ccacgctttg cagccaatcc aaaatgaaca gcgtgcgctc gatgcgcccc
    22261 agctcgcgca acgccacggc caagccgttc tggcgcgggt agctgccgag tttgcgcagc
    22321 atcagcgaag ccgttaccgt gccttgcttg atggaggtgg ccagccgcag aatttcatcc
    22381 caatgggcgc gtatttgctt gatgttcagc ctgtcgctgc taatcatcgg cttgagcgcg
    22441 tcataggcgg catcgccctt ggggatgaat agcttggttt cgcccaagtc acggatacgc
    22501 ggcgcgaagc gaaatcccag caaatgcatc aagccaaaca cgtgatcggt gaagcctgcc
    22561 gtgtcggtgt agtgttcctc gatgcgcaag tccgactcgt ggtacagcag gccatcaagc
    22621 acgtaagttg aatcacgaat gcccacgttg accaccttgg cactgaaggg cgcgtactgg
    22681 tcggagatat gggtgtagaa agtccgtaag tatctttact caaaagttgc aatcaataat
    22741 ttattgaaaa agattgaaag gtggtggtaa ataatgttac aatgtgggag tatcagttta
    22801 aattcttcgt gaaatagtgt tcttttaagc taataaaaaa tgcacgtgga atttaggtca
    22861 aagaaaagta aagaaaaatt tatttatgga ggtaaaaaag gatgagtcaa gttgttgatt
    22921 ttttaaatga agcaaaaact ttttattttg caaccgttga aggagaccag ccaagggtca
    22981 gaccgtttaa tgcagccatg gagaggaatg gcaaggtcta tcttggtaca accaatcaga
    23041 aaaaagttta tcagcagtta ttggcaaatt caaaggtgga agtctcaggt atggcaaaag
    23101 gaaaatggat tcggctcacc ggcgaagccg taattgatga taccgtggaa gcaagggaag
    23161 caatgcttga agcaaatccg cctttgagag attggtatag cgctgatgat gggaaattca
    23221 ccgtatttta tttgaaaaac atgcaggcag ttttatattc ctttacagga gatccggaga
    23281 tattagataa ttaatcaaaa catgcagccc aagtgtagaa tgaactgacc cccataagtt
    23341 agaccaaaaa tctggtgatg ctgccaactt actgatttag tgtatgatgg tgtttttgag
    23401 gtgctccagt ggcttctgtt tctatcagct gtccctcctg ttcagctact gacggggtgg
    23461 tgcgtaacgg caaaagcacc gccggacatc agcgctatct ctgctctcac tgccgtaaaa
    23521 catggcaact gcagttcact tacaccgctt ctcaacccgg tacgcaccag aaaatcattg
    23581 atatggccat gaatggcgtt ggatgccggg caaccgcccg cattatgggc gttggcctca
    23641 acacgatttt ccgccattta aaaactcagg ccgcagtcgg taacctcgcg catacagccg
    23701 ggcagtgacg tcatcgtctg cgcggaaatg gacgaacagt ggggctatgt cggggctaaa
    23761 tcgcgccagc gctggctgtt ttacgcgtat gacaggctcc ggaagacggt tgttgcgcac
    23821 gtattcggtg aacgcactat ggcgacgctg gggcgtctta tgagcctgct gtcacccttt
    23881 gacgtggtga tatggatgac ggatggctgg ccgctgtatg aatcccgcct gaagggaaag
    23941 ctgcacgtaa tcagcaagcg atatacgcag caaatgagtt tcggcaaaat caataatcag
    24001 acaacaagat gtgcgaactc gatattttac acgactctct ttaccaattc tgccccgaat
    24061 tacacttaaa acgactcaac agcttaacgt tggcttgcca cgcattactt gactgtaaaa
    24121 ctctcactct taccgaactt ggccgtaacc tgccaaccaa agcgagaaca aaacataaca
    24181 tcaaacgaat cgaccgattg ttaggtaatc gtcacctcca caaagagcga ctcgctgtat
    24241 accgttggca tgctagcttt atctgttcgg gcaatacgat gcccattgta cttgttgact
    24301 ggtctgatat tcgtgagcaa aaacgactta tggtattgcg agcttcagtc gcactacacg
    24361 gtcgttctgt tactctttat gagaaagcgt tcccgctttc agagcaatcg cgcccgattg
    24421 ctgaacagat taatagccga ttttagcatt ttatttgtaa caaaaagcta atcaaattgt
    24481 gatgctggct tcaattactg caaagtctcg ttaatcccac cactgatctt ttaatgctgt
    24541 attggtgcaa aatgcccaaa gtcttaatat gttgatataa atacaattcc cagacttcaa
    24601 tgcggcaact agcagtacca gcaataaacg actccgcacc tgtacaaacc ggtgaatcat
    24661 tactcaaaga ctttaggcta taagaggctg actaaaagca atccgaacct cattacacat
    24721 tagaacaaat ccatcttcat ggtgaaccaa agtgaaacct agtttatcgc aataaaaacc
    24781 tatacttttt aatatccccg actaaaatgc cgggactcag actattattc atgggtcccc
    24841 ggagccacta cgctgacccg gttgatttca gaggtaaggg aaaaggcgac gttgcgcctg
    24901 tggaacaaac tggcactgat accgtcagcc gaacagcgtt cacagctgga gatgctgctg
    24961 gggcggcact gttgcaaagt tagcgatgag gcagcctttt gtcttattca aaggccttac
    25021 atttcaaaaa ctctgcttac caggcgcatt tcgcccaggg gatcaccata ataaaatgct
    25081 gaggcctggc ctttgcgtag tgcacgcatc acctcaatac ctttgatggt ggcgtaagcc
    25141 gtcttcatgg atttaaatcc cagcgtggcg ttgattatcc gtttcagttt gccatgatcg
    25201 cattcaatca cgttgttccg gtactgacgg atggctggcc gctgtatgaa tcccgcctga
    25261 agggaaagct gcacgtaatc agcaagcgat atacgcagcg aattgagcgg cataacctga
    25321 atctgaggca gcacctggca cggctgggac ggaagtcgct gtcgttctca aaatcggtgg
    25381 agctgcatga caaagtcatc gggcattatc tgaacataaa acactatcaa taagtctgtg
    25441 ctcgccattg caaacgcgct gattgccatt cagaaactaa tcgagtgatt gatggcttaa
    25501 ctaagggaga gacgtttacc gcttcctgcc ctttaacaaa ggagtgttta tgagttttga
    25561 acaattattt acactaacga cccaacgtcg ttgggtttgc cgcagaaaat ttattcattt
    25621 aaaatagatc taaatgaagc gggaaactgc agacgtaaaa aaaccgactg gtgaggtcgg
    25681 cttttttaca gttccggtac gagctggtaa ctcgcccgga agagaaactc tctacaactg
    25741 acaacagtat gataatccgt gaagcctgat tatgcaatat gacaggcggt gactacgcgt
    25801 taacggtttg cttgaaagtt agataaacgt ataatcagag ggttagtgct gtggtgagtc
    25861 tttccctgca ttccgctaaa tgcggcatga acagcttcaa agtcctgaca ggtaatacag
    25921 gtggtgctgg ttatctgtgc tctggtagga gtgagactct ctacaactga caagacgaag
    25981 agaagccgtg gtgacaggca gcgtaagagc aagccacggt gtctttactc catttatgga
    26041 gaaaacggat gattaacctg ttaatcatcg ttctgagggc ggtagctgcg cttgcaaacg
    26101 cgctgattgc agttctggaa ctgatccgtc agttcatcga ttgatgactg cggaaacgta
    26161 actaagggca ggaagtgcac cgcttcctgc cctttaacaa aggaggtgtt atggatttta
    26221 tgagcatttt ggggcgctgt ttacttcttc ctttccctgt tgcgatgttt gtcggttgcc
    26281 tgtt
//
