LOCUS       NZ_CP122392             8801 bp    DNA     circular CON 30-MAY-2024
DEFINITION  Klebsiella pneumoniae strain KP9650 plasmid pKP9650-3, complete
            sequence.
ACCESSION   NZ_CP122392
VERSION     NZ_CP122392.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN34136943
            Assembly: GCF_029814845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 8801)
  AUTHORS   Li,W., Li,X., Wei,J. and Zhang,Q.
  TITLE     Genomic Characterization of Klebsiella pneumoniae strain KP9650
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8801)
  AUTHORS   Li,W., Li,X., Wei,J. and Zhang,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2023) Zhuhai hospital, Jinan University, 79
            Kangning Road, Zhuhai, Guangdong 519000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. 0.13-r308; Canu v. 1.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 139.44x
            Sequencing Technology             :: Illumina NovaSeq; PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029814845.1-RS_2024_05_30
            Annotation Date                   :: 05/30/2024 04:45:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,886
            CDSs (total)                      :: 5,762
            Genes (coding)                    :: 5,568
            CDSs (with protein)               :: 5,568
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 91 of 194
            Pseudo Genes (incomplete)         :: 119 of 194
            Pseudo Genes (internal stop)      :: 42 of 194
            Pseudo Genes (multiple problems)  :: 46 of 194
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP122392.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8801
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP9650"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKP9650-3"
                     /geo_loc_name="China: Zhuhai"
                     /lat_lon="22.28 N 113.58 E"
                     /collection_date="2022"
                     /collected_by="Zhuhai People's Hospital"
     gene            join(7535..8801,1..419)
                     /locus_tag="QCB43_RS29350"
                     /old_locus_tag="QCB43_29350"
     CDS             join(7535..8801,1..419)
                     /locus_tag="QCB43_RS29350"
                     /old_locus_tag="QCB43_29350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_214301846.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARTAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            429..686
                     /locus_tag="QCB43_RS29355"
                     /old_locus_tag="QCB43_29355"
     CDS             429..686
                     /locus_tag="QCB43_RS29355"
                     /old_locus_tag="QCB43_29355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            771..920
                     /locus_tag="QCB43_RS29360"
                     /old_locus_tag="QCB43_29360"
     CDS             771..920
                     /locus_tag="QCB43_RS29360"
                     /old_locus_tag="QCB43_29360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            2403..4364
                     /locus_tag="QCB43_RS29365"
                     /old_locus_tag="QCB43_29365"
     CDS             2403..4364
                     /locus_tag="QCB43_RS29365"
                     /old_locus_tag="QCB43_29365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_032448356.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVDRREIPLKTFPVLAKTDPLAEY
                     QSEAGRQRPGDDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            4364..5095
                     /gene="mobC"
                     /locus_tag="QCB43_RS29370"
                     /old_locus_tag="QCB43_29370"
     CDS             4364..5095
                     /gene="mobC"
                     /locus_tag="QCB43_RS29370"
                     /old_locus_tag="QCB43_29370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_094313769.1"
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVAQRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDIIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGATGWRYLHRIALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRATQVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMMMD"
                     /name="mobC"
     gene            5124..5387
                     /locus_tag="QCB43_RS29375"
                     /old_locus_tag="QCB43_29375"
     CDS             5124..5387
                     /locus_tag="QCB43_RS29375"
                     /old_locus_tag="QCB43_29375"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_094313768.1"
                     /translation="MTNRVVAVGREALLMVAVMAGTLVVLAGNLLKLLWRVLPVLLLLY
                     GVVQFLARNPEIRDWLFLHFGQGGTAAILVGGILLCMRRLMK"
                     /name="hypothetical protein"
     gene            complement(5418..5597)
                     /locus_tag="QCB43_RS29380"
                     /old_locus_tag="QCB43_29380"
     CDS             complement(5418..5597)
                     /locus_tag="QCB43_RS29380"
                     /old_locus_tag="QCB43_29380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_094313767.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     EKLWLAMRDHLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            5666..6043
                     /locus_tag="QCB43_RS29385"
                     /old_locus_tag="QCB43_29385"
     CDS             5666..6043
                     /locus_tag="QCB43_RS29385"
                     /old_locus_tag="QCB43_29385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="WP_094313766.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVMDTSE
                     LIRVYGELRQGETHERDGLRLPDETEKTAFDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTPRRWWQWGKR"
                     /name="entry exclusion protein 1"
     gene            complement(6105..6404)
                     /locus_tag="QCB43_RS29390"
                     /old_locus_tag="QCB43_29390"
     CDS             complement(6105..6404)
                     /locus_tag="QCB43_RS29390"
                     /old_locus_tag="QCB43_29390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_094313765.1"
                     /translation="MPYEVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLTAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6394..6657)
                     /locus_tag="QCB43_RS29395"
                     /old_locus_tag="QCB43_29395"
     CDS             complement(6394..6657)
                     /locus_tag="QCB43_RS29395"
                     /old_locus_tag="QCB43_29395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_094313764.1"
                     /translation="MSNTTHYENANFLRELAENLPRILPESGPDKAALLQCLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="plasmid stabilization protein"
     gene            complement(6963..7208)
                     /locus_tag="QCB43_RS29400"
                     /old_locus_tag="QCB43_29400"
     CDS             complement(6963..7208)
                     /locus_tag="QCB43_RS29400"
                     /old_locus_tag="QCB43_29400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     BGC             2535..8801
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(1024..1602)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4365..5092
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.004"
                     /coverage="100.0"
                     /evalue="1.97e-140"
ORIGIN
        1 caatgaatga atccttatcc agagataagg ctgcacttac cggggcgatg gagagccgga
       61 aacaaaagga gaaaaaagcg aaggatgcag aaaataagtt aaatgaggaa aagaacaagc
      121 ctcgcaaggg gactaaagac tacggccatg attatcatcc agtacctaaa acagaagaca
      181 taaagggact tggagagtta aagcgaggtg atcctaaaac acctaaacaa ggtggtggtg
      241 gtaagcgggc ccgatggtat ggcgataaaa aacgtaaaat ttatgaatgg gattcccagc
      301 acggtgagct tgaagggtat cgtgccagtg atggcgaaca cctaggcgca tttgatccca
      361 aaacgggtaa gcaggttaaa gggccagatc caaaacggaa cattaaaaaa tatctttgag
      421 aggtaaatat ggggcttaaa ttacgtttga catggtttga taagaaaact gaagagttta
      481 aaggggaaga gtattctaaa gactttggtg acgatggttc tgtcattgaa agcttgggaa
      541 tgcctttaaa ggataatatt aataatggtg agtttgattt gaagaaagaa tgggttcctt
      601 tactacagcc attttttaaa aatcaaataa aacctgatgt ggataattgt tatatagctt
      661 ttgattatcg ggacggtaac tggtaacaaa aaattatcaa ggatgatttg aaatactgac
      721 ttccggtgtt cagggatgaa tgccggagtc tttaaataca gggaaagtat atgaaaaagg
      781 taaagactat ttttcttttt atattgattg ttgctggctt tcttctggcc gcatgtcagg
      841 caaattatat ccgggatgtt cagggcggaa cggtggcacc atcgtcctcc tctgaactga
      901 cggggatcgc ggttcagtag aaaagatcaa aggatcttct tgagatcctt tttttctgcg
      961 cgtaatcttt tgccctgtaa acgaaaaaac cacctgggga ggtggtttga tcgaaggtta
     1021 agtcagttgg ggaactgctt aaccgtggta actggctttc gcagagcaca gcaaccaaat
     1081 ctgtccttcc agtgtagccg gactttggcg cacacttcaa gagcaaccgc gtgtttagct
     1141 aaacaaatcc tctgcgaact cccagttacc aatggctgct gccagtggcg ttttgcgtgc
     1201 tttcccgggt tggactcaag tgaacagtta ccggataagg cgcagcagtc gggctgaacg
     1261 gggagttctt gcttacagcc cagcttggag cgaacgacct acaccgagcc gagataccag
     1321 tgtgtgagct atgagaaagc gccacacttc ccgcaaggga gaacggcgga caggtatccg
     1381 gtaaacggca gggtcggaac aggagagcgc aagagggagc gacctaccgg aaacggtggg
     1441 gatctttaag tcctgtcggg tttcgcccgt actgtcagat tcatggttga gcctcacggc
     1501 tcccacagat gcaccgaaaa agcgtctgtt tatgtgaact ctggcaggag ggcggagcct
     1561 atggaaaaac gccaccggcg cggccctgcc gttttgcctc acatgttagt cccctgctta
     1621 tccacggaat ctgtgggtaa ctttgtatgt gtccgcagcg cccgccgcag tctcacgccc
     1681 ggagcgtagc gaccgagtga gcgaggaggc gcaatttccc cggcacctgc aagacggtca
     1741 ccggacgcgc tgatgtggga tattgtcccc tgattaagtc tttctattcc ctgacgatca
     1801 attatcagga taggtgaacc atgtcggttt ttcgctgaac attttacgtt aacctatctc
     1861 tgttgctttt ttctccttgc ggagaaatgc aagtcatccc cgctggggcg tggctgactt
     1921 caggggaaaa gaccttgctt acgctggctg gacgccaccg acgcacggtc ttttcccctc
     1981 tttctggctc tgtccggctg gacgccggcc acgccagaaa ttcacccggc ccccgtcagg
     2041 ctcacgcctg accacccaca aaatccacgg tgctggacgc acctgacgaa gcagcaaagc
     2101 tgctcctgat tttgcgggtg gtcagccgct cgctatggcg aactctgacg ggggccggaa
     2161 caccggaaaa gaccgcactg gggtgccgcc ttttcctctc acacgctggg gcgtgctcgt
     2221 tgttcctccg gggctgcgcc ttttccgcat ggggcggaaa gaggctggcc tccgcggtga
     2281 aagctgaacg caatcaccac ggacgtgacc gccgccgcca tgccttgggg catgtccgcg
     2341 gcttgtgcag caggggctgc acaacacgcc ggtaaacccg tcgtctgaag gagagagatt
     2401 gcatgtttaa tacggattcg cttgcctggc agtggcatat cccggagctg gcccggcaga
     2461 tttacccgtg ggtcagctgg ctgtaccggg agtattacag tctggccggt ttttttctgg
     2521 ttatcggcct gtttttcggt ctggcagaac tctgggccgg gcggatgcga ttcgtggggc
     2581 tgagtcataa ggagcggcgg gagtatgccg atcgctataa gcgcgataat aaccggactg
     2641 cgccattttc ggtgctggcc tcgctggatt cgcccgggcg gatggtcagg gcacggcgac
     2701 atgtctggaa ctacgcatac tggctgaccg gcgctgccgg tctggccctt ctgggggggc
     2761 tggttgtcgc cgtgtttatc gagagctggg gagaaaccgt cctgcgtccg gacctctacg
     2821 cgaacgcaga ttattacctg ctgcagccgg ctaacctgtt cgggattgcc tggtgtgccg
     2881 gaggtcttgt cgcaggcgtc ctcctggcgc ggctgctggc gttcctgctg cttgacgggc
     2941 attttgcggc cgctgacgag gcggtgaacg cgaaactgaa tcaggagagc cggcgcagca
     3001 gccagcggac cggagaaatg accgacgtcc gccacctgca tttcggggag ccggtaccgg
     3061 ttaacgcgct ggccgatttt tccacggagc aggcccggaa acagcaggcg gtgtttctgg
     3121 gtaaggatga gcagggccag ccggtgctgg tcccgcgtga tacctggcgc aagaccaaca
     3181 ttcagatcct cggcctgccc gggagcggca agagcgtgat ggccaccaac gcgctcattc
     3241 gctgcgtacg cgatttcggg gacgcggtgg tgtacttcga cccgaaaggg gacgcgtggg
     3301 cgccgcacgt cttccgggcg cactgcccgg acttcaccct gctggatctg cggccgggga
     3361 aaccggcgca gctgaatctg ttccgcgatc tcgaccagta cgccctgaag aatcttctgg
     3421 ttgccggatt taacctgagt gagaccggcg acgtggcgga ccactaccgc atcagcgagc
     3481 agaaagcggc gaagctgatt gcggagcagt ttccgcaggg ggcaaatatt cagcaggtgc
     3541 tggcggcggc gtacgcactg ccggaggccc tgaaaaagga cgtgaagggg ctgatcacca
     3601 agctggagaa cgtggccgac ctgagcgtcc ttcagacgga cagcggcatc gacgtggcgg
     3661 ggataatcaa cggcggcggc tgcctgtacg tcatcggctc gatggacgat gaggcggtga
     3721 tccgggtgca gaagatgctg tttgcccgct gcgcgcaaat catcattgcg cgggacgagt
     3781 tccggaggtg gccgcacgcg agcatcatgc tcgatgagat taaatatctg ctgtcgaagt
     3841 acgtgctgaa cgcgctgggg acgctgcgca gccgggactg caacctgctg ctcgcgcacc
     3901 agtcgctggg cgacttcggc cagtgcgggc aggatctgcc cgctgatttt gtgaaaacca
     3961 cggtactgga taacacgccg atccgctggt tctaccgggc ggccagccag gagtccgctc
     4021 agtgggcggc cggacagacc ggggagatcc gggtggacgt ggagcgccgc cgggccagcc
     4081 gggaggcggg gaacgtggag catatcagcg gggacagctt catccagaag gaggcgcggc
     4141 cgctgtttga cgtgaacacc ctgcaacatc tgcctgacgg gttcgcggtg atgaccgggc
     4201 tgggcgtggc gcggctggcg ttcagcagcc cgctgcgtgt tgatcgccgg gaaattccgc
     4261 tgaaaacctt ccctgtgctg gcgaaaacgg acccgctggc ggagtaccag tcggaggccg
     4321 ggcggcagcg gccgggtgat gatgattttg cggggctgta ctgatggcac tggagcgata
     4381 caacgtcagc cacgcgaagc ggcaggcacg gaacgcggag aaaacacggc tgaccctgcg
     4441 ctggctgcgg gaagaactgt gttccacggc ggagctggtt gcgcaacggc tggggattgc
     4501 ggcggtacag ccggtttacc gcttcctgga cagcctggtg gcgaaagggc tgctggtccg
     4561 ggcgaaatac ccggttgacg gccgtcaggt cagcgtgtgg gggctgacgc cgcacggggt
     4621 ggcgttctcg ttcgacgagg acgagccgct gacggacatt attccgtttc agccgtcgcg
     4681 ggtgtcggcg gcgcagctgc cgcaccggct ggccgtgcag tccctgcgcc tcgccatgga
     4741 ggcccggggg gccaccggct ggcggtacct gcaccgtatt gccctgaaag ggatgaaggt
     4801 gccggacgcg ctggcggagc tggacggcag aacggtggcg tttgaggtgg aacgcaccgt
     4861 gaagagccgc aggcgctatc aggaggtggt gtccgggtat ctgtttaacc gccgggcgaa
     4921 cggcatcgat gaaatctggt acatttgccc ggaccgggcg acgcaggtca gggtgcaacg
     4981 ggctattctg gcggtggatg aaatcgtgaa cccgcagacc ggcgaggccc gcaaaacggt
     5041 ggagctggac cgggagcggc tgtttgcgtg ctttaaattc atgatgatgg actgagctta
     5101 tacattcact cagagaggtt tttatgacaa atcgtgttgt tgccgtgggg cgtgaagccc
     5161 tgttgatggt cgctgtcatg gccgggacgc tggtcgttct ggccggaaac ctgctgaaac
     5221 tgctttggcg cgtactgccg gtgcttctgc tgctctacgg ggttgtgcag tttctggcga
     5281 ggaacccgga gatccgtgac tggctgtttc tgcatttcgg gcagggaggc acggcggcca
     5341 ttcttgtcgg gggaatactc ctctgtatgc gccgcctgat gaaataatgc cggacagcac
     5401 cggctcggcc ggtgctgtta ttcctccccg agatggtccc gcattgccag ccagagcttt
     5461 tctgcatcct catgcagccg ttcgcacatg tcggccgggg tatccatatc cagctcgttc
     5521 agtttctcga gcaacagcag cgactggtcc ttaatgaatt tcgccatgtt gagggcggtt
     5581 ttttcctgct tcgtcatgtt tctgtccttc cgggcacggt ctgcgtctgt cgggtatact
     5641 gtctcaaaaa tagcggggtg agacaatggc gtgggtgacg gtgagacagg cgacggaact
     5701 gacggggaaa gcccggagtt ccctgtatcg ggatatggcg aaaggccgcg tatcataccg
     5761 tacggaagct gatggtggtc gggtgatgga taccagcgag cttatccggg tgtacggtga
     5821 gttaagacag ggtgagactc acgagcggga cgggttgaga ctgccggatg agactgaaaa
     5881 aacggccttc gacgcgttga tcgcggagat aaaagcactc agggaggagg tggccggact
     5941 gcggcaggaa atgcaggcca tgagactgct ggaacacaaa ccggagacag cagagacacc
     6001 ggccggaaca ccgcgccggt ggtggcagtg gggaaaacgc tgacgcgctg tgcttgtcca
     6061 accggcgacg gccacgcaat gaattgcgcc cccgtcaccg gttatcagcg aacggtatgg
     6121 ggattctggc gctggccaac cacggccaga acccggactt tcctggtctg gtcatcaaca
     6181 tcatacagga catgctgtcc catcagactg atccggcgaa cgtcctcgcc atagcgtgag
     6241 tccacttcat agaggcgcgg gaagtcggcc agtttgtccg ccgcagtgag aacgcgatcg
     6301 gtaacgttct gcgcatccca cagggatgaa ttttccgcga tatagtcaaa cagcgtcgtt
     6361 acatcctcga tggctccctg tttccattcc acctcatacg gcatcgcgca gttcctgata
     6421 acggccatgc aggcgctggc ggagttgttc cgtggtcatg cccggacgcg tgtcagcacg
     6481 ggcggcggtt actttggcgc gaacctgatc ttcatactct gcctgggcca gttcttcgtt
     6541 agccaggcat tgcaacaacg cagctttgtc cgggccactt tccggcagta tgcggggcag
     6601 gttttcagcc agttcccgca ggaagttggc gttttcgtag tgtgtagtgt tgctcattgc
     6661 ggagactccc ggattaatgg ggtgatatga agaagtttag cagggggcgg tctgaaagaa
     6721 tatgctcgtg tcagtcaggc tgatgaagac gaaagctggt aaaaaagggc ttacggcacc
     6781 cattttacgt caaactgcac gccatgcagt tgcgtgcata ggcatgcatt aggataaagt
     6841 ttaccgggcg cgtttccggc ggttttccgg gtggtttgtt gcctgtttta tcccgtagcc
     6901 gccggaaatg ccctcagacc gtctgagcgg tgcgcgtaat gcgacgttat ggtaaatacc
     6961 ccttaccggc ggcgctgtgg ctgccaggtg aaggtggttt ccgtagcctc gtatttctcc
     7021 cgacgcattt cctgcgcccg cctggcttca cgttcgtcct gaatggcacg aagcaccctt
     7081 tcccgcacct gttgttttac cgcctttggc agcgttttgt tccctttcag gcccatggcc
     7141 agtgcctgag cgacaaaggc gtccgccagg cgcttttctt cagcgggagt cagtttcagg
     7201 tgcgtcatag tggcctccgg gcgtctcagg tttcccgaac agtttaaccg caggtcctct
     7261 cctcatgcca gttagctttc agatgtgtct ataccatctg aaatgtaagt gtgatgaatg
     7321 tcttaaataa taaaatttgt tgccatgaga aattttcggg aaaagacgcg atctgcttac
     7381 aggtggctcc gggcgctttt ttgtgcctga agatgagaac taatctcata tattgacacc
     7441 tgaaaacggg aggagtaagg taataattat actgtgtata tgtacagtat gttggcttta
     7501 atttattgtt ttaaatgtca aagaggaaaa cgatatgagt ggtggagacg gtcgaggtcc
     7561 gggtaattca ggtctgggac ataatggtgg tcaggccagt gggaatgtga acggtacgtc
     7621 tggtaaaggt ggcccttcat caggtggtgg tacggatcca aacagcgggc cgggctgggg
     7681 tacgacgcat acgccgaatg gagatattca taactataat ccgggggagt ttggtaacgg
     7741 cgggagtaaa cccggtggta atggtggtaa cagcggcaat catagcggta gctctggtgg
     7801 cggacagtct tcggccactg cgatggcctt cggtctgcct gccctggcta ctccgggggc
     7861 tgaaggactg gctttatcag tttccggcga tgcgttgtcg gccgccgttg ctgatgtgct
     7921 ggctgccctg aaggggccgt ttaagtttgg tctgtggggg attgcgatct acggtgtgct
     7981 gccttctgag attgcaaaag atgatccgaa aatgatgtca aaaattatga cgtcattacc
     8041 ggccgatgcg gtgacggaga ctccggcaag tactttacca ctggaccagg cgacggttcg
     8101 tgtcagacaa cgggttgtgg atgtggtgaa ggatgagcgg cagcatattg cggttgtcgc
     8161 aggtcggcca atgagtgtcc ctgtggtgga tgcgaaaccg acaaaacgtc cgggggtatt
     8221 cagtgtgtcg attccgggtc tcccgtctct gcaggtgagc gtaccgaaag gtgttccgac
     8281 agcgaaagcc ccgccaaaag gcattgttgc tgaaaaaggt gattcacgtc cggctggttt
     8341 tacagccggt ggtaactccc gtgaggccgt tattcgtttc ccgaaagaga ccggacagaa
     8401 gccggtttat gtgtcggtga cagatgttct taccccggca caggtaaaac agcgtcagga
     8461 ggaagaaaag cgtcgccagc aggcatggga cgccgctcat ccggaagagg ggctgaaaag
     8521 agactatgat aaagcgaaag ctgagctgga tgccgaagat aaaaatattg cgaccttaaa
     8581 cagccgcatt gcatcgacag agaaggcgct ccccggtgca aggactgctg ttcaggaagc
     8641 cgataaaaag gtaaaagagg cagaggcaaa taaagatgat tttgtgactt ataacccgcc
     8701 tcatgaatat ggctccgggt ggcaggatca ggttcgctat cttgataagg atattcagaa
     8761 tcagaatgag aaattaaaag cggctcaggc atctttaaac g
//
