LOCUS       NZ_CP121498            24920 bp    DNA     circular CON 11-APR-2024
DEFINITION  Staphylococcus epidermidis strain 24FSE04 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP121498
VERSION     NZ_CP121498.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33711672
            Assembly: GCF_029691875.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24920)
  AUTHORS   Pitton,M.
  TITLE     S. epidermidis isolates collected from patients with left
            ventricular assist device
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24920)
  AUTHORS   Pitton,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2023) Intensive Care Medicine, Inselspital, Bern
            University Hospital, Freiburgstrasse 18, Bern 3010, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-DEC-2021
            Assembly Method                   :: Flye v. 2.8.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 277x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029691875.1-RS_2024_04_11
            Annotation Date                   :: 04/11/2024 17:07:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,452
            CDSs (total)                      :: 2,368
            Genes (coding)                    :: 2,292
            CDSs (with protein)               :: 2,292
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 50 of 76
            Pseudo Genes (incomplete)         :: 30 of 76
            Pseudo Genes (internal stop)      :: 25 of 76
            Pseudo Genes (multiple problems)  :: 22 of 76
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP121498.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24920
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="24FSE04"
                     /isolation_source="Forehead"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="unnamed2"
                     /geo_loc_name="Switzerland: Bern"
                     /lat_lon="46.9473 N 7.4247 E"
                     /collection_date="2020-10-06"
                     /collected_by="Inselspital"
     gene            complement(join(23986..24920,1..277))
                     /locus_tag="QA611_RS11435"
     CDS             complement(join(23986..24920,1..277))
                     /locus_tag="QA611_RS11435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017551895.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_161387123.1"
                     /translation="MNEDRLWNKNFIIVCLSNFFLYLIFYLLFTTVAVYASDNLNANTS
                     QAGLATGIFIIGVLIARLLAGRFVDQVGAKKILYIGAVLSIITTVGYLFSSSIFILDII
                     RLLHGFSLGVAITGTGAIVARIVPESKRGEGIGYFALSTPLGAGVGPLIGTLVTQHYSF
                     SANVVFCILLVVMSFTLSLFLNVPRIEALVEDKKEVAFKEKSKGFSLSNFFEPHALPIA
                     FIALLVGSAYASIISFINTYAVSIHAVQIASFFFLFYAATTAISRPFVGKLFDIKGENV
                     VLYPAFISLAVGLLLISLASVWPWLILLSGVFVGLGYGTFTASGQAIAVQEAPTVKAGL
                     ATSTFYILLDGGAGIAPSLLGLFIPFLGFNGLYVIMAIVAIIAGILYVIVHGRKASKRC
                     SYNH"
                     /name="MFS transporter"
     gene            complement(270..713)
                     /locus_tag="QA611_RS11440"
     CDS             complement(270..713)
                     /locus_tag="QA611_RS11440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003254514.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_161387124.1"
                     /translation="MNETYLKIDDVAQQTGLSKRTLRYYEEIGIIPPSERSNGGVRLYS
                     PTIIKRLNDIVRAKDVLGLTLQELQEFLSLRELLDNQRTEYRASTNDLIKQEKLQEIID
                     IINNQLNMIEQKKENMQQVEQELLDLRERGLTLFNKKGDDKNE"
                     /name="MerR family transcriptional regulator"
     gene            complement(1177..1410)
                     /locus_tag="QA611_RS11445"
     CDS             complement(1177..1410)
                     /locus_tag="QA611_RS11445"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202596476.1"
                     /translation="MEVFKISIEKAKEYKNYGNLSSIVMRASAISLFFLLIIKFTFEWS
                     FSDYFTNFFKGTFILVTVIDAIPNFLEKNVNV"
                     /name="hypothetical protein"
     gene            <1507..>1623
                     /locus_tag="QA611_RS11450"
                     /pseudo=""
     CDS             <1507..>1623
                     /locus_tag="QA611_RS11450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489187.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /name="LysR family transcriptional regulator"
     gene            complement(1654..2589)
                     /locus_tag="QA611_RS11455"
     CDS             complement(1654..2589)
                     /locus_tag="QA611_RS11455"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_278270175.1"
                     /translation="MALATVTIASAPAIGPVYGGLIIHLLNWKYMFLFPIPFLLISMFI
                     GLKCLSNVNNSKIANTTLKGIVGVSVLLTGILILINKLLINFWHAIIGLTLIFVGYVII
                     KLKSIKFINIKFVKNKYVFINLVIFSLLQFFSLSLSYLIPTMVQTVFNINALNASFVVI
                     IGSFMNALFVVIGGFLLDRLGIKIIYIGLLLNTLSFALSLFTYMSVLCLAINYGLFMIG
                     LGLSYGNIMTNTLTNTHEYAKTDVNTVFSTMQTYTGSIGVILTGTIVTLFQNSYGLVRG
                     IENATFFILSTFFILSIIEVIFFNIIRKNI"
                     /name="MFS transporter"
     gene            complement(2589..2984)
                     /locus_tag="QA611_RS11460"
     CDS             complement(2589..2984)
                     /locus_tag="QA611_RS11460"
                     /inference="COORDINATES: protein motif:HMM:NF012312.4"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_278270177.1"
                     /translation="MNKVLYFKIISIGTLAFFSVLLETSLNIAFPNLKNFFSKNYDTLN
                     WLTTGYLLTSTFIVATATYLQNRYSEKQLFIVSWITFFIGCILALISNNFYLLLIARCI
                     EGIGSGIAIPLLFLTVITQAPPKKWVV"
                     /name="MFS transporter"
     gene            complement(2977..4152)
                     /locus_tag="QA611_RS11465"
     CDS             complement(2977..4152)
                     /locus_tag="QA611_RS11465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016526677.1"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_161387126.1"
                     /translation="MMKPNYLLKENFFEKIFSPYHSKSKQKIIIVEHCVTNTVDFIKYL
                     SNYYDVYFIPKPNSLDKDIMNILEDYVTFLFINKEQLKNKKELINLIDEYVGKSKFYII
                     DIGGYFSWNYKVINEYYSNQILSIIEDTENGLQKYEKEIKNLKENNLVQRVPICTVARS
                     ILKIEEDFLVGNEVAIKSEVFLSEFGTNLIGKKVLVIGFGKIGSSLSQSLKHRGAIVYV
                     LDKQAVRQAFAISQGYLYEDFDNLLNNLDIIYIANGEKSIDMDYLNRKCSGKLYIFSVT
                     SVDDTFKNIEHFKNALEIESKVPYYSLNTELEGSIIVANKGNAINFTYTNSTLASFVQM
                     TQGEMLLLLNDKVKTITNSGITELKKADQENIAKIWLEEYIALKNTGGKFE"
                     /name="NAD(P)-dependent oxidoreductase"
     gene            complement(4152..4799)
                     /locus_tag="QA611_RS11470"
     CDS             complement(4152..4799)
                     /locus_tag="QA611_RS11470"
                     /inference="COORDINATES: protein motif:HMM:NF014069.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="WP_161387127.1"
                     /translation="MDVSNIYNFMSKKLMMDKTGHGISHIKRVENIAKKIASEEKIQNK
                     EWEIIQACVYLHDIIDDKITENIDLAKKEVIDILKESNAKEKEIEIIMYIINNMSYSKN
                     LKKKITLNKIGQIVQDADRIDALGAVGISRAFYYGGSKGHSMYNDNKARPISELNENNY
                     RNNSSVINHFYEKLLVLHTTMNTEEGKKIAYQRTETMKEFLEKFKNEVEGNL"
                     /name="HD domain-containing protein"
     gene            complement(4882..5511)
                     /gene="pyrE"
                     /locus_tag="QA611_RS11475"
     CDS             complement(4882..5511)
                     /gene="pyrE"
                     /locus_tag="QA611_RS11475"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: protein motif:HMM:TIGR00336.1"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_161387128.1"
                     /translation="MTFSEYIVNFNIIQFGNFTLKSGRKSPYFFNFGLFNNGEMINKLG
                     EYYADTIVEANIDFDIVYGSAYKGIPIALSTVMALKTKYGINKGYTFNRKEEKKHGDKG
                     IYVGSDLTNKKVLSVDDVLTSGKTTVETKKFIDTNGGELVASLVALNRGEQYFNNSNCS
                     AEVGLKNQYNIDILSITNITDVLETLNNNKMFEEYKKLDSYIKEYV"
                     /name="pyrE"
     gene            complement(5519..6520)
                     /locus_tag="QA611_RS11480"
     CDS             complement(5519..6520)
                     /locus_tag="QA611_RS11480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_161387129.1"
                     /translation="MIHNSLEDLIGNTPILSIKGGLVPYNKELLLKLEYFNPNFSIKDR
                     TAFGLIKYSIENGNLRPGDIIIESTSGNLGKSLAMFGASKNFEVILIVDPKIDKSLLNM
                     YKAYGADVITVTEKDDKGGYQKTRINKVKEIINSNPEKRYFWPNQYENIFNQKYHYQVT
                     SNEFLNINTDFITSPVSTGGHLSGIAKKLKELNKKLDIIGADVRGSCIFENNPKSYLLN
                     GVGLSWKSNNLKEEYLDWYSIVSDELAISVCRYFSENYGLLIGGSAGLSIATALKALQT
                     SDYNKGLAIVPDTGINYLNQIYDDKWVSDNGISLKQGKELYESINAIKIKEV"
                     /name="pyridoxal-phosphate dependent enzyme"
     gene            complement(6520..7719)
                     /locus_tag="QA611_RS11485"
     CDS             complement(6520..7719)
                     /locus_tag="QA611_RS11485"
                     /inference="COORDINATES: protein motif:HMM:NF012766.4"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="WP_161387130.1"
                     /translation="MYNISKLKEIFEETKCDVLVAVTKENVQYFSGFSPVCKTLRPYTS
                     DTYIVIHKNDLSTINVIHSLGEIDQVIDKYPDVQLNKVYTYGDFYREYIEADLNNDERK
                     IKEYSQKQYNYNSASEALLAMLKDLKAKSVLLDDEGLNFKKYKEISWKLKNLDLIDGSY
                     EIKRIRSIKTESEIQLLKKSANIIEYAINHIKNLSNTSLTEDLIVKEFNKCVASYGGVP
                     VLPMIKIGRQSVGGQRQPNNSVEFPEESFIWFDCDISYKGYWSDVARIIISKHSQYKYQ
                     KEYNILHQAQREAIQKLRPGMKASEAYNLVMNYAIQNGMKHYKRNHVGHGIGLEPYEMP
                     VLSRDNDQVIEENMVLCIETPYYEYGLGALHVEDLVLIKEEGNIVLNQTSGDLIEWEDE
                     "
                     /name="Xaa-Pro peptidase family protein"
     gene            complement(7712..8107)
                     /locus_tag="QA611_RS11490"
     CDS             complement(7712..8107)
                     /locus_tag="QA611_RS11490"
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_161387131.1"
                     /translation="MIHYNCACLIKIKNKKIFLVRTHDNEKYYLPGGKIEENETLDEAL
                     LRELKEELSLNVTGDEVVFWKTIQGAAYPDTNKTVLLNCFFLKKTTFDYTIKNEINHAK
                     FVSIYDEETMAPAVINVVKALEEDNYV"
                     /name="NUDIX domain-containing protein"
     gene            complement(8094..9494)
                     /locus_tag="QA611_RS11495"
     CDS             complement(8094..9494)
                     /locus_tag="QA611_RS11495"
                     /inference="COORDINATES: protein motif:HMM:NF023222.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-hydroxylase N-terminal
                     domain-containing protein"
                     /protein_id="WP_161387132.1"
                     /translation="MNNLCDGRKVYINGNLVEDVLDIPILKNTYKYVCKYYSMQKERDY
                     HTYLEGDNRYSKTFYPPKSKQDLKEKRQVYYDISNESHGMLGRTPDFLNPGLMSLYFHS
                     DFLGENKYANFTSNAKDYYIYAKNKDIFVSHASINPQIDRSKKISEIENKYSGVYINSY
                     DRDNVYVSGAKMIVTLSPLADELLIFNMPGLKPGDEDYAIAFSVPVNTEGIKIISRKTI
                     DKPDFSRFDYPLSNSMEEIDAYVIFEEVAVPWNRVFVFKDIDKSNQFFDKSKIRNHTGH
                     QDITRGLVKLEFLTGTAIELANILGLNKFINIQEELGYLTSSIELIKAGIYLCEENAEQ
                     SNGIYNPDIVAIQSVRYHLPFIYKRGIDLLQKLAAGSMLAIPTHKDYNNENKKILNESL
                     KSKLSTSEYRTKLLNLSWDITGEAFGQRQKVYEYYHAGDPMRIGASHYLNYDNESLIAK
                     VRELLDTL"
                     /name="4-hydroxyphenylacetate 3-hydroxylase N-terminal
                     domain-containing protein"
     gene            complement(9487..10221)
                     /locus_tag="QA611_RS11500"
     CDS             complement(9487..10221)
                     /locus_tag="QA611_RS11500"
                     /inference="COORDINATES: protein motif:HMM:NF014273.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="WP_278270186.1"
                     /translation="MYIDFIKIEKIYLHEKTEKQRLEKLKAKVTREKTQRNPIIVTEYN
                     QGYLVLDGAHRYTTLKEIGCQYAMCQVVEENDYSIKMWKHQITYDDFLKINPKLDDCSF
                     INAKSIECFFKDECLKINISNYECDNLVLYKYKELVSKINRCNSFKRILNISGNNLNDE
                     VLIVYPSLTIDIIKNIVSKGETIPAGISRVDLKCGRVLSVNIPLEILNNPKRHLSVSKN
                     INTNLRKYEDTVYMYEGDMIYE"
                     /name="ParB N-terminal domain-containing protein"
     gene            complement(10236..10805)
                     /locus_tag="QA611_RS11505"
     CDS             complement(10236..10805)
                     /locus_tag="QA611_RS11505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_145436673.1"
                     /translation="MNNICFFCGSNSGLDENFTEQTRNLIKYVKENHYNIVYGGGKIGL
                     MGVVAEEGMKHNINVTGIMPKFLIDKEIGNSEISKLIEVSDMSERIQVMLKMSEGFIVL
                     PGGFGTFEEFFEILSWSQMGLHKKPIGLLNINGFFDPLENLLEGCIQSGFAPKENKNLF
                     IIEKDPESLIKKMKDFRHTMPNKYVN"
                     /name="TIGR00730 family Rossman fold protein"
     gene            complement(11376..11825)
                     /locus_tag="QA611_RS11510"
     CDS             complement(11376..11825)
                     /locus_tag="QA611_RS11510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="WP_161387113.1"
                     /translation="MILISACLVGQNVRYDGGNKLNSELKTLVDQGLAKPICPEVLGCL
                     TTPRNPAEIVGGDGFDVLKNKAKIIDNQGNNVTDEYINGAIKALDICKEMKCKTLILKS
                     DSPTCSSQNIYSGQFDGSKKQGVGIFAALLIKNGIQIYDEKNYKI"
                     /name="DUF523 domain-containing protein"
     gene            12088..>12503
                     /locus_tag="QA611_RS11515"
                     /pseudo=""
     CDS             12088..>12503
                     /locus_tag="QA611_RS11515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501032.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            12536..13210
                     /locus_tag="QA611_RS11520"
     CDS             12536..13210
                     /locus_tag="QA611_RS11520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_161387114.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLIYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13291..13986)
                     /locus_tag="QA611_RS11525"
     CDS             complement(13291..13986)
                     /locus_tag="QA611_RS11525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020368001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_049393709.1"
                     /translation="MKSVKILSEELGVSKQTIFNNIKRLNIETIKQENTSFIKENTDIE
                     KIIQRVNENKKKYGFESTTEEKQKKESDNSNIKSKSDTQIIEILKKQIDTLNEQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQILALESNKKIQKLEHQLEEERQLNYSFDKSTNDR
                     ENVDVQEASYTSDSVNTDQYQKEEKKPEVQPKDISENQQDDSFNQNDKDIAIEETQTKK
                     GFWSRLFGG"
                     /name="DUF536 domain-containing protein"
     gene            14414..15364
                     /locus_tag="QA611_RS11530"
     CDS             14414..15364
                     /locus_tag="QA611_RS11530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020365660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_049393712.1"
                     /translation="MSNFKRIAIQEFEKERFYKLYKFLFEDDYFKKLSDSSKIAYCMFR
                     DRFELSKMNNWIDESGNVYLIFTTKDLCNLLNCGTQKVTKIKKELENFNLLEQERMGLN
                     KPNKIYILEPQTPFKYNSNKEFRKSKFQSFENQNSRVLKVKKQEFRKSKSNDTDSSDTD
                     YIETKNNDTNDTNDTSKMISNNSHSNHTNHQQTEFNNEALKFQVLEELPSQIKSYLSNF
                     EIKDIRIIKSVLLKGKKSFNNAHDTYYRLEDVEFELVSVLKRFKAMLLQKDESIEAMQG
                     YLMQSIKAELEEMHALNMRRQNAPQKNIFHTSNHW"
                     /name="replication initiator protein A"
     gene            complement(15355..15924)
                     /locus_tag="QA611_RS11535"
     CDS             complement(15355..15924)
                     /locus_tag="QA611_RS11535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="WP_049393716.1"
                     /translation="MKKDKRSNKWAFLIYEESTPSDYRDILEQMHIPYILSPWHNQDID
                     YSTGSIKKSHKHGALFFDSLKSYSQVSELLQQNLNSPSHVEIIMSPKGMFDYFIHASNP
                     DKTPYDINDIETGCGFDLNQFLLEQGQSEIFNAIIDLIESQDFTEFQNLVIYARQHHPS
                     YLNLIIQRTYFFAKYLDSRRHTSNHQ"
                     /name="replication protein"
     gene            complement(16055..16657)
                     /locus_tag="QA611_RS11540"
     CDS             complement(16055..16657)
                     /locus_tag="QA611_RS11540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_049393728.1"
                     /translation="MRKTYFMRVYNITFYLFIWAILTFLFSQVFHLLKNTLAQSDDIYI
                     SKITPYVTFISKGLYHITFYFLDIALLLVGIDLVIRLLKDKITNHIKSVYHTIILRRYI
                     KIDVEKVPSKDNQSKDEAKNSAVQQYFNKVVGKSLVDVRQKEVFVAIKIPRKHQAHKIL
                     NDIENQIYKEITYQHPDYYFSTPERQNRYLWFKGQRR"
                     /name="hypothetical protein"
     gene            complement(16657..17733)
                     /locus_tag="QA611_RS11545"
     CDS             complement(16657..17733)
                     /locus_tag="QA611_RS11545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002272712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="WP_161387115.1"
                     /translation="MTSKDLEKYLLQSLNMALGSIMQGETSYTNSFSCKVTEEGFYFLP
                     RLPAGYIIDDELYQKIFLIASAALYPKFTLLKQSSAYFVPMDTNDIHTQRALFFPWQQG
                     ISERLVITDLDRFTSTLTNQHIPIMKQLTLNYQKITSIAIAGNSGSGKSYMLTYLLSVL
                     EHISDLIIVDPKFDTPSRWARIHDINVIHPHQNRSKSDFLSEVNENLSYCLQIIQRRQT
                     TLYDDPDYQFEHLTIVIDEVLALAEGVNKAIKDAFFSLLSQIALLGRATKVHLLLVSQR
                     FDHQTIPISVREQLNVLIQIGNINKKTTQFLFPDLDPEGIVIPIGKGTGLIQVIDSESP
                     YQVLPLLCPTYYTKEGIL"
                     /name="cell division protein FtsK"
     gene            complement(17733..18053)
                     /locus_tag="QA611_RS11550"
     CDS             complement(17733..18053)
                     /locus_tag="QA611_RS11550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002466864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_278270162.1"
                     /translation="MKITQKFNKGGYSAEIASNYIDNKKPIYSLSSELYPQQRFENNQP
                     TGEIIAYKAWFIQEGLPPFMVKFESEVTLPNFMTVITLENLEACEIRYDVYFKASDIKE
                     VK"
                     /name="hypothetical protein"
     gene            complement(18135..18566)
                     /locus_tag="QA611_RS11555"
     CDS             complement(18135..18566)
                     /locus_tag="QA611_RS11555"
                     /inference="COORDINATES: protein motif:HMM:NF019886.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0016987 - sigma factor activity [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_161387117.1"
                     /translation="MNQVKSKREANIQIAYKNGDWDTISKLLNQSYENARRKDRYYQVL
                     SLNYPNINSQGQISELENFIASSTLTPIECLLLKERQIEVNKALSLLSKTDYEMIIDFY
                     LDHKSYSQISREVGISDKTVKKRIIKATTFLKQSLENIT"
                     /name="sigma-70 family RNA polymerase sigma factor"
     gene            18874..19365
                     /locus_tag="QA611_RS11560"
     CDS             18874..19365
                     /locus_tag="QA611_RS11560"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_278270165.1"
                     /translation="MNLEKMMDHMIGDKIRKLRKTLGLTQERFCEKYENKVSIDKYRLS
                     AIENGRREKNKNPHYLTKDQLIFFSDLMNEDITTFIYGDTQRKHQLIKLMLLNIFMNGT
                     TESGHTMDPKVEQTPFFEFNNDQEFFRLSYFNLDNNELKNMASDMNFDMHREKNILNKS
                     "
                     /name="helix-turn-helix transcriptional regulator"
     gene            19539..20171
                     /locus_tag="QA611_RS11565"
     CDS             19539..20171
                     /locus_tag="QA611_RS11565"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_278270167.1"
                     /translation="MSIVESLETFRLAGLLLRQRRSSYYIDNYLRGDGSFGSKATDWKE
                     MGYRIFITSFNEFYQQHAEVFFEFFEKNIFQSHYHAITNERINSLLQSDRFLNVLNEVY
                     ENDQYIPNRMLGHNFSRSMIQKLSLVEERSKRLAKKDNDLENKTIIDPIEYYDLVQVYQ
                     ERIQDTYDIDRYLYDLENMTLLFVDKDKDDKSTGLFLPEYFNITPLK"
                     /name="hypothetical protein"
     gene            20206..21027
                     /locus_tag="QA611_RS11570"
     CDS             20206..21027
                     /locus_tag="QA611_RS11570"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_161387119.1"
                     /translation="MNIKDQIDISKIILQIISMLVPLVGIILSQFKGTERRMDQKKEKM
                     KRIFNNIFRFIFVIVLIDLLILVELRDFYINIKPENLIKYKKDIYQLILILTTFSTVYA
                     FFLMPFWLKKKRYYEIELEHTKGKKIVCVVLNRDKSKNKDVIIYKDDKKEYEEDVDSIK
                     QREGRVTFIPKAKSIFNINRSAIEETKTLPIWSRWLFFILIILVSLVGIFSCIEMIMNV
                     WTFNLGKRVVMFRIIISIFPITIFMYFIAIIKFLYQSWLGKNKLVYEKSKK"
                     /name="hypothetical protein"
     gene            21227..21322
                     /locus_tag="QA611_RS11575"
     CDS             21227..21322
                     /locus_tag="QA611_RS11575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000493115.1"
                     /translation="MFSTLFVTIIAPIVVGVILTLFSHWLNNREK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            21541..22443
                     /locus_tag="QA611_RS11580"
     CDS             21541..22443
                     /locus_tag="QA611_RS11580"
                     /inference="COORDINATES: protein motif:HMM:NF014021.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="WP_161387120.1"
                     /translation="MTIPIKKLDHWSQKGATQAPKNLREKIEKVLTANESKIKRKNQLD
                     IYLQGSYRNNTNIFGNSDVDIVVQSNATFFSNISKLEAYERKIYNQTFDEATYTWRYFK
                     NDVIETLQYAFGSSNVEIGNKSIKIFTEDYEADVIPCFEYRNYLSFGNSEEDREYIPGI
                     KFFTTDKGEGIINYPKKHYVFGVDKNERTNNYYKSTIRIFKNIKKQLIKQKRITKKVVS
                     SYFIESLLYNVPDRYFCIDNASNRVADILNWLTKNQDSFSAFICQNEQINLFGSSQEQW
                     NEEDADKFIFEINKFWNEW"
                     /name="nucleotidyltransferase"
     gene            22534..23049
                     /locus_tag="QA611_RS11585"
     CDS             22534..23049
                     /locus_tag="QA611_RS11585"
                     /inference="COORDINATES: protein motif:HMM:NF037740.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_161387121.1"
                     /translation="MIINLLIEKIPYIEITISITTISIFGILYTLFDKFIWKWKILHKL
                     GIIKIPNLNGKWKGKFQSSYHDFKENLPVVLIIEQSWSKICIKGKFNHSKSSSDTASIK
                     VNLGKEIKLHYSYYNDKKPEYYKMGTSNHRGYANLEINGNSMEGNYFNDPSNNKNWGTL
                     NLKKVIES"
                     /name="hypothetical protein"
     gene            23152..23763
                     /locus_tag="QA611_RS11590"
     CDS             23152..23763
                     /locus_tag="QA611_RS11590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487382.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_161387122.1"
                     /translation="MIVGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGQSIENRPI
                     FQEVLNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDNDDLF"
                     /name="recombinase family protein"
     Typing          complement(13385..13985)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.281"
                     /coverage="81.0"
                     /evalue="0.0"
     Typing          14415..15321
                     /name="rep_cluster_1216"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.706"
                     /coverage="97.0"
                     /evalue="0.0"
ORIGIN
        1 aataaccaac tgttgtaata atacttaaaa ctgcgccaat gtataatatt tttttagcac
       61 ccacttgatc aacaaatctt cctgcaagta aacgagcaat taatacacca ataataaaaa
      121 tacctgttgc taatccagct tgacttgtat tcgcatttaa gttatctgat gcgtatacag
      181 ctacagtcgt aaataataag tagaagatta aatataagaa gaaattagat aaacagacaa
      241 taataaaatt cttattccat aatctatcct cattcatttt tgtcatctcc ttttttatta
      301 aataacgtta acccccgttc acgtaagtcc aataattctt gttccacctg ctgcatattt
      361 tctttcttct gctcaatcat atttaattga ttgttaataa tgtcgattat ctcttgtaac
      421 ttctcttgtt taatcaaatc gttggttgat gctctatact ctgtacgttg gttatctaat
      481 agttctcgta acgatagaaa ttcttgtagt tcttgcaatg ttagtcctaa aacatcttta
      541 gccctaacga tatcgttaag ccgtttgatg atagtaggag aatacaagcg cacgcccccg
      601 ttactacgtt cagatggtgg gatgatacct atctcttcat aataacgtaa cgtccgttta
      661 ctcagccccg tttgttgggc aacatcatca atttttaagt aagtttcatt catactcata
      721 actcccttat acttgtgtta tttatcgcca ttaaatagta tacatatcat ttaacgttaa
      781 ttttaaatat actaaaataa atagctctaa gatgaattgt taaagattac cttagagctt
      841 ctttttggtt cttttgcaaa gttaaaatta tatgaacatc tatacaaaac tataaaagca
      901 aatattgttt taacagtaaa gagttttgtt agtattaatt atttttcgtt tttcagtata
      961 aatattacat gatttttaac tttgcaaaag aaccttatac tgattagata ttgcttctgc
     1021 tttaaaaata tactgtttta attcttcgtt tttgatagct taaaagaaaa aggagtaaat
     1081 tatgtttaat ttaaaacttt ttgataattt acaatttcaa aatacaaaaa gtatcgaaat
     1141 cataattaag ataaatatca aatcccaaat cccaaattat acattcacat tcttttctaa
     1201 aaaatttgga atagcatcaa taacagtaac taatataaaa gttcccttaa aaaagttagt
     1261 aaaatagtct gaaaaagacc attcaaatgt aaatttaata attaataaga aaaacaatga
     1321 aattgcggaa gccctcataa caatgcttga taaatttccg taatttttat attcttttgc
     1381 tttttctata gatattttaa acacctccat aaataatatt aaattctaaa cttacattgt
     1441 cagaaatcac tctgcttttg taattacacc tcattatctt ttaaagttaa ttttactgaa
     1501 tgtgccgttt tagttattga aaataacact tcgcttttaa ttgaggaatt ttataaagat
     1561 aatatgaatg ttgttatcgg tgatattaca catttaaaaa ataactcgct atatatagaa
     1621 gaggtttaat actaaaaatt atttcaccat atattagata ttttttctaa taatattaaa
     1681 aaatattact tctattatac ttaatataaa aaaagtacta agtataaaaa acgttgcgtt
     1741 ttctatacct ctaactaatc cataagaatt ttgaaataaa gttactattg ttccagtcaa
     1801 aataactcct attgatcctg tatatgtttg cattgttgag aatacggtat taacatcagt
     1861 tttagcatat tcatgagtgt tagttaatgt attggtcata atgttaccgt atgataggcc
     1921 taaacctatc ataaataatc cataatttat tgctaagcat aaaacactca tgtatgtaaa
     1981 taaagataaa gcaaaagaaa gtgtatttag taatagtcct atgtatatta tttttatacc
     2041 taaacgatct agtagaaatc cccctataac tacgaaaaga gcattcataa aagatccaat
     2101 tataaccaca aaagatgcat tcaatgcatt aatattaaaa actgtttgga ccatagttgg
     2161 tattaaataa gaaagtgata aagaaaaaaa ttgaagtaaa gagaaaatta ccaagtttat
     2221 aaagacatat ttatttttta caaatttgat atttataaac tttatacttt tgagctttat
     2281 tatgacataa cctacaaata ttaaagttaa tcctataata gcatgccaaa agttaataag
     2341 aagtttatta atgagtatta gaattcctgt tagtaatact gaaactccta ctataccctt
     2401 taatgttgta tttgctattt tagaattatt tacattactt aaacacttaa gtcctatgaa
     2461 cattgaaatt aatagaaatg ggataggaaa aagaaacata tacttccagt ttaataaatg
     2521 gattatgagg cctccataaa caggtcctat agcaggtgct gaagcgattg ttacagtagc
     2581 taaagccatc atactaccca cttttttggg ggagcttgtg ttattacagt taaaaataat
     2641 aatggaatag ctattccaga tcctatgcct tcaatgcatc tagctattaa aagtaaataa
     2701 aagttattac taatcaaagc taatatacat cctataaaaa atgttatcca tgatacaata
     2761 aacaattgct tttctgagta tctattttgt agatatgtag ctgttgcgac aataaaagta
     2821 gaagtaagaa gatatccagt agttaaccaa tttagcgtat cataattttt tgaaaaaaag
     2881 ttttttaaat ttggaaatgc aatatttaat gaagtttcta ataatacact aaaaaaggct
     2941 aatgtaccta ttgatataat tttaaaatac aatactttat tcaaatttac ctcctgtatt
     3001 ctttaaagct atatattctt ctagccaaat tttagctata ttttcttgat ctgctttttt
     3061 aagttctgta attcctgaat ttgtaattgt ttttacttta tcattaagta gtaatagcat
     3121 ttcaccttga gtcatttgta caaacgaggc taaagttgaa tttgtatatg taaaattaat
     3181 agcatttcct ttattagcaa caataatgga gccctctaat tcagtattta aagaataata
     3241 tggaacttta ctttctattt ctaaagcatt tttaaaatgt tctatattct taaaagtgtc
     3301 gtctacagat gtaactgaaa aaatatataa ttttcctgag cattttctat ttaaataatc
     3361 catatctata gacttttctc catttgctat atatataata tctaaattat ttaatagatt
     3421 atcaaaatcc tcatataaat atccttgaga aatggcaaat gcttgtctta ctgcttgctt
     3481 atctaagaca taaactatag cacctctatg tttcaaagat tgggataaac tactaccaat
     3541 ttttccaaaa cctataacta aaactttttt accaattaaa tttgttccaa attcagataa
     3601 aaacacttct gatttaatag caacttcatt tcctactaaa aaatcttctt ctattttcaa
     3661 aatacttcta gctacagtac atataggtac tctttgaact aagttatttt cttttaaatt
     3721 tttaatttct ttttcatatt tttgtaaacc gttttccgta tcctctatta tacttaatat
     3781 ttgattagag taatattcgt ttataacttt ataattccaa gagaaatatc ctcctatatc
     3841 tataatataa aatttagatt ttccaacata ttcatctata agattaatca attctttttt
     3901 atttttcagt tgttctttat ttataaacaa gaatgtgaca taatcctcca atatattcat
     3961 aatatcttta tcaaggctat taggtttagg tataaaataa acgtcataat aattacttaa
     4021 atattttatg aaatctacag tattagttac acagtgctca acaattatta tcttttgttt
     4081 acttttagaa tgataaggag aaaaaatttt ttcaaaaaaa ttttctttta ataaatagtt
     4141 gggtttcatc attataaatt accttccact tcgtttttga atttttctaa aaattctttc
     4201 atagtttctg ttctttgata tgctattttt ttcccttctt ctgtattcat agtagtatgt
     4261 aaaactaata atttttcata aaaatggttg ataacactac tattatttct ataattattt
     4321 tcgtttaatt cactaattgg tcttgcttta ttatcattat acatagagtg ccctttggaa
     4381 ccgccataat agaaggctct agatattcct acagctccta aagcgtctat tctatctgca
     4441 tcttgaacaa tctgacctat tttatttaat gttatttttt tctttaagtt tttagagtaa
     4501 gacatattgt ttattatata cataattatt tctatttctt tttcttttgc attagattct
     4561 tttaatatat ctattacttc ttttttagct agatctatat tttcagtaat tttatcatca
     4621 ataatatcat gcaagtacac acatgcttgt ataatttccc attctttatt ttgtattttt
     4681 tcttcagaag ctatcttttt agctatattt tcaacacgtt ttatgtgaga aatcccatga
     4741 cctgttttat ccatcattaa ctttttgctc ataaaattat aaatatttga tacatccata
     4801 aaatagtaac ctctttcagc aaattattga tataaaatat atattaaaaa taaattattt
     4861 aaaaaagaga tgttatcatc tctaaacata ctcttttata tacgaatcta attttttata
     4921 ttcttcaaac attttattat tatttagagt ctctagcaca tcagtaatat ttgttataga
     4981 taatatgtca atattatatt gattttttaa tcctacttcg gcagaacagt tactattatt
     5041 aaaatattgt tctcctctat ttaaagctac taagctggca acaagttctc cgccatttgt
     5101 atcgataaat ttttttgttt caactgttgt tttaccagag gttaatacat catcaactga
     5161 taacactttt ttattggtta aatctgaacc tacatatata cctttatcac catgcttttt
     5221 ttcttctttt ctattaaaag tataaccttt attaatacca tattttgttt ttagagccat
     5281 aacagtagat aaagctatag gaataccttt atatgctgaa ccataaacta tatcaaaatc
     5341 aatatttgct tcaacaattg tatctgcata gtattctcct aatttattta tcatttctcc
     5401 attattaaat aatccaaaat taaaaaagta tggacttttt ctacctgact ttaacgtaaa
     5461 attaccaaac tgtataatgt taaaattgac aatatattca ctaaaagtca taaataattt
     5521 acacctcttt tatttttatt gcatttatac tttcatataa ttctttgcct tgtttaaggg
     5581 aaataccatt atcacttacc catttatcat cataaatttg gtttaaatag ttgatacctg
     5641 tatctggaac aatagctaaa cctttattat aatcgcttgt ttgaagagct tttaaagctg
     5701 tagctattga aagtcctgca gatcctccta ttagaagacc ataattctca gaaaaatatc
     5761 tacagactga tatagctaat tcatcggaaa ctatcgaata ccaatctaag tattcttctt
     5821 tcaaattatt acttttccaa gataatccga caccatttaa aagataagat ttcggattgt
     5881 tttcaaaaat acaagatcct cgtacatctg ctcctataat atctaatttt ttatttagct
     5941 ctttcaattt ttttgctata ccagaaagat gtccccctgt acttactggt gaagtaataa
     6001 aatctgtatt tatgtttaaa aattcatttg atgtaacttg ataatgatat ttttggttaa
     6061 atatattttc gtattgatta ggccaaaaat atcttttttc tggattggag tttataatct
     6121 cttttacttt attaatcctt gtcttctgat atccaccttt atcatctttt tctgtaacag
     6181 ttataacatc tgctccataa gctttgtaca tgtttaataa agacttatca attttaggat
     6241 ctacaattaa aatgacttca aaatttttac ttgctccaaa catagctaaa gatttaccta
     6301 agttaccaga agttgattct ataataatat cacctggtct taaattgcca ttttcaattg
     6361 aatatttaat aagaccaaac gctgttcgat cttttatgct aaagttagga ttaaaatatt
     6421 ctaattttaa aagtaactct ttattatatg gaaccaatcc ccctttaata cttaatatag
     6481 gtgtattacc tattaaatct tctaaagagt tgtgtatcat cattcatcct cccattctat
     6541 taaatctcct gaagtttgat taaggactat attcccttct tcttttatta aaactaaatc
     6601 ttctacatgt aatgctccta acccatattc ataataaggt gtttctatac atagaaccat
     6661 attttcttct attacttgat cgttatctct agataaaaca ggcatttcat atggctctag
     6721 ccctattcca tgaccaacat gattacgttt ataatgtttc attccgtttt gaatagcgta
     6781 attcattact aaattatatg cttctgaagc cttcattcct ggtcggagtt tttgaatagc
     6841 ctctcgttgt gcttgatgta atatattata ttctttttga tacttatatt ggctatgctt
     6901 ggatataata attcttgcta catcagacca atatccctta taagatatat cgcaatcaaa
     6961 ccaaataaat gattcttctg gaaattcaac agaattattt ggttgtcgtt gtccacctac
     7021 agattgtcta cctattttga tcattggtaa tacagggact cccccataag atgcaacaca
     7081 tttattaaat tccttaacta taaggtcttc agtaagtgat gtattagata aattttttat
     7141 gtgatttata gcatattcta ttatattggc tgacttcttt agtaattgta tttctgattc
     7201 agtcttaatg cttcttattc ttttaatttc ataagatcca tctattaaat ctaaattttt
     7261 taatttccaa ctaatttctt tatatttttt aaaattaagc ccttcgtcat caagaaggac
     7321 tgatttagct tttaagtcct ttaacatagc taataaagct tcacttgcac tattataatt
     7381 atattgcttt tgagaatatt cttttatttt cctttcatca ttattcaaat ctgcttctat
     7441 atattctcta taaaaatcac cataagtata cactttattt aattgaacat caggatattt
     7501 atcgattacc tgatctattt ctcctaagga atgtataaca tttatagttg ataaatcatt
     7561 tttatgaatt actatataag tgtcacttgt ataaggtctt aatgttttac atacaggtga
     7621 aaaaccagag aaatactgaa cattttcttt agtaactgct actaaaacat cacacttagt
     7681 ttcttcaaat atttctttca acttacttat attatacata gttatcttcc tccaaagctt
     7741 taacaacatt aataactgca ggagccattg tctcttcatc atatatagaa acaaatttag
     7801 cgtgattaat ttcgttttta atagtataat caaaagtggt tttttttaaa aagaaacaat
     7861 ttaataaaac tgttttatta gtatcaggat aagctgctcc ttgtattgtt ttccaaaata
     7921 ccacttcatc tccagtaaca tttaatgaaa gttcttcttt aagttctctt aacaatgctt
     7981 catcaagtgt ttcattttct tctatttttc cacccggtaa ataatatttt tcattatcat
     8041 gagttctaac taaaaatatt tttttatttt taatttttat taaacatgca caattataat
     8101 gtatcaagta attccctcac ttttgcaatt aaactttcat tgtcataatt taagtaatga
     8161 ctagcaccta ttctcatagg atctcctgca tgataatatt catatacttt ttgacgttga
     8221 ccgaatgctt ctcctgttat atcccaacta agatttaata acttcgttct atattctgat
     8281 gtacttaatt tagactttaa actttcattt aaaatttttt tattttcatt gttgtaatcc
     8341 ttatgtgtag gtattgccaa cattgatcct gctgctaact tttgtaataa atcaatgcct
     8401 cttttataaa taaatggtaa atgatatcgt acagattgaa ttgctactat atcaggatta
     8461 tatataccat tgctttgttc tgcattctct tcacataaat atataccagc ctttattagt
     8521 tcaatagaac tagttaagta tcctaattct tcttgaatat taataaattt attcaagcct
     8581 aatatattcg caagttctat cgctgttcca gttaaaaatt caagtttaac taatcctctt
     8641 gttatatctt gatgtcccgt gtggtttcga atttttgatt tatcaaaaaa ttggtttgat
     8701 ttgtcaatat ctttaaatac aaaaactcta ttccaaggta ctgctacttc ttcaaatatg
     8761 acatatgcat ctatctcttc catagaattc gaaagagggt aatcaaatct cgaaaaatca
     8821 ggtttatcaa ttgtttttct tgatataatc tttatacctt ccgtatttac tggtacagaa
     8881 aaagcgatag cataatcttc atccccaggt tttaaaccag gcatgttaaa tattaaaagt
     8941 tcgtctgcca aaggagataa tgtaactatc attttagctc cacttacata aacattatct
     9001 ctatcataac tatttatata tacacctgaa tatttatttt ctatttcact aattttttta
     9061 gatctatcta tttgaggatt tatagatgca tgagacacaa aaatgtcttt atttttagca
     9121 tatatataat aatcttttgc attagaagta aaattagcat atttattttc acctaaaaaa
     9181 tctgaatgaa aataaaggct cattagacct ggatttaaaa aatctggtgt tctgcctaac
     9241 ataccatgag attcattaga gatatcataa tatacttgtc tcttttcctt taaatcctgt
     9301 ttagattttg gaggataaaa cgttttagaa tatctattgt caccttctaa gtatgtatga
     9361 taatcacgct ctttttgcat tgaataatat ttacaaacat atttatacgt attttttaat
     9421 ataggaatat ctaaaacatc ttcaactaaa ttaccattaa tatatacttt tcttccgtca
     9481 cataaattat tcatatatca tatctccttc atacatatat actgtatctt cgtattttct
     9541 taaattcgta ttaatatttt tacttacact aagatgtctt ttaggattat tcaatatttc
     9601 taaaggaata ttaacggata aaacgcgtcc acattttaaa tcgactctgc ttattccagc
     9661 cggtatagtt tcgcctttag aaactatatt tttaattata tcgattgtaa gactaggata
     9721 tactatcaat acttcatcat ttaagttgtt accacttata tttaaaattc ttttaaaaga
     9781 gttacatcta ttaattttag atacaagttc tttatattta tataaaacta aattatcgca
     9841 ttcataattg cttatattta tttttaaaca ttcatcttta aaaaaacatt caatactttt
     9901 tgcatttata aaactacaat catctaattt gggatttatc tttaaaaaat catcatacgt
     9961 tatttgatgt ttccacatct ttattgaata atcgttttct tctacaacct gacacatagc
    10021 atattggcat cctatttctt ttaaagtagt atatctatgt gccccatcta aaactaaata
    10081 tccttgatta tattccgtaa caataatagg atttctttgt gttttctctc ttgttacctt
    10141 agcttttaat ttttctaatc tttgtttttc tgttttttcg tgtaagtaga ttttttctat
    10201 tttgataaaa tcaatataca cattttatcc tccttttaat taacatattt atttggcatt
    10261 gtatgacgaa aatctttcat tttttttatt agtgactctg gatctttttc tattataaat
    10321 aaatttttat tctccttagg cgcaaagcct gattgtatac atccctctaa aaggttttct
    10381 aacggatcaa aaaagccatt aatatttaat aaccctatgg gttttttatg taatcccatt
    10441 tgactccaag ataaaatttc aaaaaattct tcaaaagttc caaagccacc gggtaataca
    10501 ataaatcctt ccgacatttt taacattact tgtattcttt cactcatgtc tgaaacttca
    10561 atgagtttac ttatctcact atttcctatt tctttatcaa tcagaaattt aggcattatt
    10621 cctgttacat taatattatg tttcatacct tcttcagcaa ctactcccat tagaccaatt
    10681 tttccacctc cataaacaat attataatga ttctctttta catatttgat tagatttctt
    10741 gtttgttctg taaaattttc atctaaaccg ctattagatc cacaaaaaaa acaaatatta
    10801 ttcattaaat atatcctcct agaattctct ttatataatt atattatcat aagaataata
    10861 taattatagt cttttaaaga gcttctgtta ctttgattat ctctacctta attaatacat
    10921 gaacaatacc agcaactaga acaatttatg agagatcaaa ataagactaa ttgtcctaac
    10981 ctttttgaag attaacttca attactaaat gaaagagcgt attggaaaat acatcatgga
    11041 gagatggtta taataaccta ttaaaaaacg aaaaatttta tacgtagaat aataaaatgt
    11101 tctagaaagg gcttaaaatg caaagtaaaa agactactca ttttttgaat agtctggaga
    11161 atagctataa tgttgtgcaa ttaaaaatga gcactgtatt gagcatatca cacgcattta
    11221 tgccgagaaa atttattgat gttgagaaga acccttaact aaacttgcag acgaatgtcg
    11281 gcatagcgtg agctactaag ccgactattc gacaagtttt gggattgtta agggttccga
    11341 ggctcaacgt caataaagca attggaataa agcaattaaa ttttatagtt tttttcatca
    11401 taaatttgta ttccgttttt tatcagtaaa gcagcaaata tacctacccc ttgtttttta
    11461 ctaccgtcaa attgaccaga atagatattt tgagaactac atgttgggct gtcagatttt
    11521 aaaattagtg ttttgcattt catttcctta caaatatcta atgcttttat cgctccgttt
    11581 atatattcat ctgtgacgtt atttccttga ttgtcgataa ttttagcttt atttttcaat
    11641 acatcaaaac catcgcctcc tacgatttcc gcaggatttc ttggggttgt taaacatcct
    11701 agaacttcgg gacaaattgg ttttgctagt ccttgatcta caagagtttt caattcacta
    11761 ttgagtttgt tacctccatc gtatcgaaca ttttgaccaa ctaaacatgc gctaatgaga
    11821 atcatatttt gacctccaga tttgggtttt agaaacgagt tgaaaacgag tttcttcttg
    11881 tcctgatact aagggtaact attgccggcg aggctaatta cccttaagtt attgatatga
    11941 ctggtttcaa acacaaaaaa gttgcttttt ctagcatact attgtaacgt ttatggtgtc
    12001 gaatcaaaaa cgtgaataga aaggagaaaa agcaactttt ttattatcat agtttgtgaa
    12061 aactaagttg ttttgatgta ttataacata gagaagtata ctgaaaaaaa acaaagaaat
    12121 caagtatttc agaaatttat taaacgtcat attggagaga atcaaatgga tttggtcaaa
    12181 gattgtaata catttctgtc ttttgtagct gataaaactt ttgaaaaaca gaagttgtat
    12241 aaagctaatt cttgtaaaaa tcgattttgt cctgtctgtg cttggcgtaa agctcgttaa
    12301 gatgcgttag gtttatcttt gatgatgcaa tatattaagc agcaagaaaa caaagagttt
    12361 atctttttaa ctttaacgac acctaatgta aatagtgatg aattagaaaa tgaaataaaa
    12421 ggttacaata attcttttag aaaacttata aagagaaaaa agtagatagt gttataaagg
    12481 gttctgttgt aaagttgaat ttatagtata attttaataa aaaggaatct tttgtatgaa
    12541 ctatttcaga tataaacaat ttaacaagga tgttatcact gtagccgttg gctactatct
    12601 aatatatgca ttgagttatc gtgatatatc tgaaatatta agggaacgtg gtgtaaacgt
    12661 tcatcattca acggtctacc gttgggttca agaatatgcc ccaattttat atcaaatttg
    12721 gaagaaaaag cataaaaaag cttattacaa atggcgtatt gatgagacgt acatcaaaat
    12781 aaaaggaaaa tggagctatt tatatcgtgc cattgatgca gagggacata cattagatat
    12841 ttggttgcgt aagcaacgag ataatcattc agcatatgcg tttatcaaac gtctcattaa
    12901 acaatttggt aaacctcaaa aggtaattac agatcaggca ccttcaacga aggtagcaat
    12961 ggttaaagta attaaagctt ttaaacttaa acctgactgc cattgtacat cgaaatatct
    13021 gaataacctc attgagcaag atcaccgtca tattaaagta agaaagacaa ggtatcaaag
    13081 tatcaataca gcaaagaata ctttaaaagg tattgagtgt atttacgctc tatataaaaa
    13141 gaaccgcagg tctcttcaga tctacggatt ttcgccatgc cacgaaatta gcatcatgct
    13201 agcaagttaa gcgaacactg acatgataaa ttagtggtta gctatatttt tttactttgc
    13261 aacagaacca tatatttttt caaacaatca ttagccacca aacaaacgac tccagaagcc
    13321 ttttttagtt tgggtttctt ctatagcaat atctttatca ttttgattaa atgaatcatc
    13381 ttgttgattc tcagatatat ctttaggttg aacctctggt ttcttttctt ctttctgata
    13441 ttgatcagta tttacagaat ccgaagtata tgatgcttct tgtacatcaa cgttttctcg
    13501 atcattagta gatttatcaa aggaataatt taattgtctc tcttcctcta attgatgttc
    13561 caatttttga atctttttat tgctttctaa ggctaaaatt tgttggtttt caagtaattt
    13621 tgacctttcc tgcaactctt ttctatagaa ttcaattgtg gtttcatgac gactttcttg
    13681 tttttcaatt tgttcattta aagtatcaat ctgttttttt agaatttcta ttatttgagt
    13741 atcacttttc gatttaatat tactattatc tgattctttt ttttgctttt cttctgtagt
    13801 actttcaaaa ccatatttct ttttgttttc attgactctt tgaatgattt tttctatatc
    13861 ggtattttct ttaataaatg aagtattttc ctgttttatt gtctctatat ttaatcgctt
    13921 aatgttatta aaaatcgttt gcttactgac ccctaattct tcacttaaga tttttacact
    13981 tttcacttta tcaacccttt ataaaatgtt tataaaccct ttacattata aacttatata
    14041 gttttataat caaagccatt attagttaga gatgagaaaa ttaaattttc atcaacactt
    14101 tgtcaaaggt tgatgacgat tagcaaagtt catcaacact ttaccaacct ttgacaaagt
    14161 attattttct tcttttataa gcttatttaa agtgctataa tagtcttaac acattaaaaa
    14221 ccccaactac tggtaatagt cggggtacgg taataaaacg ttgcagcacg tttgtttaat
    14281 atcaaattta tacttgtatt atataatgaa taacacctta gcgcaagcac ttaaatcatt
    14341 aaataaatgt aacgctatat aaaagcgttt tattacctct taccaaacta aatttcggaa
    14401 agaggttttt attatgtcaa atttcaaaag aattgcaata caagaatttg aaaaagaaag
    14461 attttataaa ctttataaat ttttatttga agatgattat tttaaaaaac ttagtgattc
    14521 ttcaaaaatt gcttactgta tgtttagaga tcgttttgaa ttatctaaaa tgaataattg
    14581 gattgatgaa agtggaaatg tatatttaat atttactacc aaagatttat gtaatctttt
    14641 aaattgcgga actcaaaaag ttactaaaat taaaaaagaa ttagaaaact ttaacttatt
    14701 agaacaagaa agaatggggt taaacaaacc aaacaagata tatatattag aaccccaaac
    14761 accttttaaa tacaatagta acaaggaatt tcgaaaatca aaattccaga gttttgaaaa
    14821 tcaaaattcc agagttttga aagtcaaaaa acaagaattt cgaaaatcaa aatctaatga
    14881 tactgattca agtgatactg attatataga gactaaaaat aatgatacga atgatacgaa
    14941 tgatacatct aaaatgattt ctaacaattc tcattcgaat catacaaatc atcaacaaac
    15001 cgaatttaat aatgaggcct taaaattcca ggtgcttgaa gaattacctt cgcaaatcaa
    15061 atcttattta agtaattttg aaattaaaga catccgtatt attaaaagtg ttttactcaa
    15121 aggaaaaaaa tcatttaata atgcacatga tacatattac cgtttagaag acgtcgaatt
    15181 tgaacttgtg agtgttttaa aacgttttaa agccatgttg ctacaaaaag atgaaagcat
    15241 tgaagccatg caaggctatt taatgcaatc aattaaagct gaacttgaag aaatgcatgc
    15301 cttaaatatg cgtcgtcaaa atgcgccaca aaaaaatata tttcatacat caaatcattg
    15361 gtgatttgat gtatggcgtc tagaatctaa atattttgcg aaaaagtaag ttcgttggat
    15421 aattagattt aaatacgatg gatgatgttg tcgcgcatat atcactaagt tttgaaattc
    15481 tgtaaagtct tggctttcaa tcaaatcaat aatggcatta aaaatttcag attgtccttg
    15541 ctcaagtaaa aattgattta aatcaaaccc acaaccagtt tcaatatcgt tgatatcata
    15601 aggagtttta tctggattag aggcatgaat aaaatagtcg aacatccctt taggagacat
    15661 aataatttca acgtgactgg gtgaatttaa gttttgttga agtaattcag agacttgaga
    15721 ataacttttt aatgaatcaa agaataaagc cccatgttta tgcgacttct tgatagatcc
    15781 tgttgaataa tctatatctt gattgtgcca tgggctcaaa atataaggaa tatgcatttg
    15841 ttcaagaata tctcgataat cagagggtgt gctttcttca taaattagga atgcccattt
    15901 atttgaacgt ttatcttttt tcatagggga tctcctttct gtgattattg attaatgatg
    15961 gcatgggggt cgtagtaacc ccatgccatc ttacaaattg tcaaagggcg tttgtgcctt
    16021 tcactacgtg aaacacaacg ccctttgaca tccatcatcg tctttgtcct ttaaaccata
    16081 aataacgatt ctgacgttca ggtgttgaaa agtaataatc gggatgctga taagtgattt
    16141 ctttataaat ttgattttca atatcattga gaattttatg agcttgatgt tttcgaggta
    16201 ttttaatggc aacaaaaact tccttttgtc taacatcaac aagtgattta cctaccactt
    16261 tgttaaaata ttgttgtaca gcactatttt ttgcttcatc ttttgattga ttatccttag
    16321 acgggacttt ttcaacatct attttgatat aacgtcgcaa tataatagta tgatagacag
    16381 acttaatatg attcgttatt ttatctttta ataaacgaat cactaaatca ataccaacaa
    16441 gcaatagagc gatatcaaga aagtaaaaag tgatatgata taagcccttt gaaatgaatg
    16501 taacataggg cgttatttta cttatataga tatcatcgct ttgtgctaaa gtgtttttta
    16561 aaagatggaa gacctgactg aagaggaaag ttaaaatggc ccaaatgaat aaataaaaag
    16621 tgatgttata cacacgcata aaatatgttt tcctcatcat aagatacctt ctttcgtata
    16681 gtaagtagga cataataatg gcaagacttg atagggggac tcgctatcaa tgacttgaat
    16741 cagccccgtt cctttcccaa taggtatcac aataccttcg ggatccaaat cgggaaacag
    16801 aaattgcgtt gtctttttat tgatattacc gatttgaatg agaacattaa gttgttctct
    16861 taccgaaatt ggtatggttt gatgatcaaa ccgttgagat accagcaata aatgtacttt
    16921 ggttgcacga cctaataaag caatttgtga tagtaatgaa aagaaagcat ctttaatagc
    16981 tttattcaca ccttcggcca aagcgaggac ttcatcaatc acaatggtta agtgttcaaa
    17041 ttgataatct ggatcatcgt acagagttgt ttgacgccgt tgaatgattt gaagacaata
    17101 actcaagttt tcattcacct cagataaaaa atcagattta gatcgatttt gatgaggatg
    17161 aatcacatta atatcatgaa tacgtgccca tcgactggga gtatcaaact tgggatcaac
    17221 aataatgaga tcagatatgt gttccaatac acttaataaa taggtcaaca tataagattt
    17281 accactgcct gaattgcctg cgattgcgat ggatgtaatc ttctgatagt ttaaggttaa
    17341 ttgtttcatg atcggaatgt gttggttcgt tagcgtagaa gtgaaccgat ctaagtccgt
    17401 aattactaag cgctcagata tcccttgttg ccatggaaaa aacagcgcac gttgtgtgtg
    17461 aatatcatta gtatccatag gaacgaaata tgcagagctt tgttttagca gtgtaaactt
    17521 ggggtataaa gctgcacttg cgataagaaa tattttttga tataactcat cgtcaataat
    17581 gtagcctgca gggaggcgag gaagaaagta aaaaccttct tccgtaacct tgcagctaaa
    17641 actattggta taacttgtct ctccttgcat aatagatccg agtgccatat ttaagctttg
    17701 aaggagatac ttttctagat cttttgatgt cattatttaa cctccttaat atctgatgct
    17761 ttaaagtaaa catcataacg aatttcgcaa gcttctaagt tttctaaagt aatgaccgtc
    17821 ataaaattcg gcaatgtcac ttcactttca aacttgacca tgaaaggtgg caatccttct
    17881 tgaataaacc aagctttata cgcaatgatt tctccagttg gttgattatt ttcaaaacgt
    17941 tgttgcggat aaagttcact acttaagcta taaatgggtt tcttgttgtc gatatagttt
    18001 gaagctattt cagctgaata cccaccttta ttaaatttct gtgtaatctt catataatgc
    18061 actccttatt tccttcttaa attaattcct acttattagg agaaaaatta aaagtatctc
    18121 ggaaagcata tctattaagt aatattttct agagattgct taagaaaagt tgttgcttta
    18181 ataattcgct tttttacagt tttgtcactg ataccaactt ctctactgat ttgtgaataa
    18241 cttttatgat ctaaataaaa gtctataatc atctcataat cggttttact taatagagac
    18301 agtgctttat ttacttcaat ttgacgttct tttaataaaa gacattctat aggtgttagt
    18361 gtggaactag cgataaagtt ttcaagttct gatatttgac cttgtgagtt tatattagga
    18421 taatttaaag aaaggacttg atagtatcta tctttacgtc gagcattctc ataagattga
    18481 ttgagtaatt tagatatagt atcccaatct ccattcttat aagcgatttg tatattagct
    18541 tctcttttac tttttacttg gttcatatat cagtcactcc ttcaatatgt gtaaatatag
    18601 aaagaaacga catttttgat ataaaaaagc acaccaaatc aacggtgaaa catgttatat
    18661 caaactttta tataaataat aaaagcttaa tcgtttcaat ccgtccgttt gatgcgcatc
    18721 tataggactg tgtaatcaaa gatcactttg atttagttat atcttctcaa aaaatacgat
    18781 tgaagtagtt agtaaaaatt gtcgcttttt atcttggaaa tctaccaact ttttgaaaat
    18841 gttactcaat taccaatata tggaggtttc gtaatgaatt tagaaaaaat gatggatcat
    18901 atgatcgggg ataaaataag aaagttaaga aagacactag gtttaacaca agagagattt
    18961 tgcgaaaagt atgaaaataa agtaagtatt gataaatata gactatcagc aatagaaaat
    19021 ggcagaagag aaaaaaataa aaatcctcat tatcttacta aagatcaact tatatttttt
    19081 tctgatttaa tgaatgaaga tattacaaca tttatttatg gggatactca aagaaagcat
    19141 caattaataa aattaatgtt attaaatatt tttatgaatg gaactactga atcaggtcat
    19201 actatggatc ctaaagtaga gcaaacacca ttctttgagt ttaacaatga ccaagaattt
    19261 tttagactat cttattttaa tttagataat aatgagttga agaatatggc gtctgatatg
    19321 aactttgata tgcataggga aaagaatata ctgaacaaga gttaaataat agaaaaagaa
    19381 aaatattgaa agaattacaa aaatacgatg atttctttta taatgaagat ttttctcgat
    19441 attataattt attaatggat ggaaaacagt gtttttcgaa gcaatcttct atactattaa
    19501 aatgcttatt tggaaatttt gactttgctt atgaattttt gtcaattgta gaaagtttgg
    19561 agacattccg tttagcaggt cttctactta gacaacgaag atcaagctat tatattgata
    19621 attatcttag aggcgatgga agttttggat ctaaagcgac agattggaag gaaatgggtt
    19681 atagaatatt tataactagc ttcaatgaat tttatcaaca acatgctgaa gtattctttg
    19741 agttctttga aaaaaatatt tttcaatcac attatcatgc tataacaaat gaacgtatca
    19801 attcactact ccaaagtgat agatttttaa atgtattaaa tgaggtctat gaaaatgatc
    19861 aatacatacc taatagaatg ttagggcata atttttcaag gtcaatgatt caaaagttat
    19921 cattggtaga agaacggtcg aaaaggttgg ctaaaaaaga taacgattta gaaaataaaa
    19981 caatcattga tccaatagaa tactatgatt tagttcaagt ttatcaggaa agaatacaag
    20041 atacttatga tatagatagg tatttatatg atttagaaaa tatgacttta ttatttgttg
    20101 ataaagataa agatgataag agtacagggt tgtttttacc agagtacttt aatattactc
    20161 ctttgaaata aatttatttc aaagataata aaaggataaa tagaaatgaa tattaaagat
    20221 caaatagaca tcagtaaaat tattttacaa atcattagta tgcttgttcc gttagttggt
    20281 attatactga gccaatttaa agggactgaa agaagaatgg accaaaagaa agaaaaaatg
    20341 aaacgcatat ttaataatat atttaggttt atatttgtaa tagtattgat agatttactt
    20401 atattagtgg aacttagaga cttttatata aatattaagc ctgaaaatct gattaaatat
    20461 aaaaaagata tctatcaatt aattttaata ttaacaactt tttctacagt atatgctttt
    20521 ttcttaatgc cattttggct aaaaaagaag agatattatg aaatagaatt ggaacacaca
    20581 aaagggaaaa aaatagtttg tgtggtattg aatagagata aatcaaaaaa taaggatgta
    20641 ataatatata aagatgataa aaaagaatat gaagaagatg ttgattcaat taagcagaga
    20701 gagggacgag ttacatttat tccgaaagca aaatctatat ttaatattaa taggtcggct
    20761 atagaagaaa ctaaaacatt acctatatgg agcagatggt tattttttat attgataata
    20821 ttagtttctt tagttgggat ttttagttgc attgaaatga taatgaatgt ctggactttt
    20881 aatttaggaa aaagagtagt aatgtttaga ataattatat ctatattccc aattactatt
    20941 ttcatgtatt ttattgccat aattaagttt ttatatcaat cttggttagg aaaaaataaa
    21001 ttagtatatg agaagagcaa aaaataataa aggtaaatca ttaatagact ttaatagaaa
    21061 aatgtatctc taaaatcgta agactgaaat taagtcagac caatagatat ttaaaaacat
    21121 aatttcactt atcggaagtt atctgtaact caattattag aaatgatata atacaaaggt
    21181 cgtcgttcac ttctgtgctg tatttagcat gggaggaggt gacatcatgt tcagtacact
    21241 atttgtaact attatagctc ctatcgtagt aggagttata ctcacattat tttctcattg
    21301 gctgaataat cgtgagaaat aatttagcgg cgacatatag ctaatacacc aaaagagccc
    21361 gataactatt cgcagtagtt atcgggctcg gtgtttatca tgctagtaca ctatttgtta
    21421 actaaattat aacactagtt agtagagaaa tgcaaaattc tattttcagt agctactttg
    21481 aaattattat gtttcataat tgtactataa ttataataat aaagaagttg gaggatattt
    21541 atgactatac ctataaaaaa attggatcat tggtctcaaa aaggtgctac acaagcacct
    21601 aaaaatttaa gagaaaaaat agagaaagta cttactgcta atgaatcgaa aattaagagg
    21661 aaaaatcaac ttgatatcta tcttcaaggg tcttaccgaa ataatacgaa tatctttggg
    21721 aatagtgatg tagatattgt tgttcaaagt aatgctactt tttttagcaa tatttcaaaa
    21781 ctagaagctt atgaacgaaa aatatataac caaacatttg atgaagcaac ttatacttgg
    21841 agatatttca aaaatgatgt aatagaaact ttacaatatg cttttggaag ttcaaatgtt
    21901 gaaattggta acaaatcaat aaagatattt acagaagact atgaagctga tgttatacca
    21961 tgctttgagt atagaaatta cttgtctttt ggaaatagtg aagaagatag agaatatatt
    22021 cctggaatta aattttttac tactgacaaa ggggagggta tcattaatta tccgaaaaag
    22081 cactacgtct ttggagttga taaaaatgag agaacaaata attactataa atctactata
    22141 agaatattta aaaatataaa aaaacaatta attaaacaaa aaagaattac aaaaaaagta
    22201 gtttcatctt attttataga gagtttatta tataatgttc cagaccgata tttttgtatt
    22261 gataatgctt ctaatagagt tgcagatatt cttaattggt taactaaaaa tcaagattct
    22321 ttttcagcat ttatatgtca aaatgagcaa attaatttgt ttggctcttc gcaagaacag
    22381 tggaatgaag aagatgcaga taaatttatt tttgaaataa ataaattttg gaatgagtgg
    22441 taaataatgc atgagtacag tattgatgta gaaaataata aagtcatctt ttatttatct
    22501 atagtctcaa tttttatttc gagtgtttta actatgatta taaatttatt gatagaaaaa
    22561 attccctata ttgagattac tatatctatt acaacaatca gtatttttgg cattttatat
    22621 actttattcg ataaatttat ttggaaatgg aaaattcttc ataaattagg gataattaaa
    22681 attccaaatt tgaatgggaa atggaaaggt aaatttcaat cttcttatca tgatttcaaa
    22741 gaaaatctcc cagttgtatt aattattgaa caatcatggt caaaaatttg tattaaagga
    22801 aagtttaatc attctaaatc atcaagtgat acagcttcaa taaaagttaa tttaggtaaa
    22861 gaaattaagt tacattattc ttattataat gataaaaaac cagaatatta taagatggga
    22921 actagtaatc atagaggata tgcaaatttg gaaataaatg gaaactcaat ggagggaaat
    22981 tactttaatg atccttctaa taataaaaat tggggtacgc taaatttaaa aaaagttatt
    23041 gaatcataag tgtattatag aggtacaccc taatcataca aatggaattg ttgaatttat
    23101 agcaatctca atgtatgatt agggtgtata ttaattgcga ggtgggaatc aatgattgta
    23161 ggttatgcta gagtttcttc catcgatcaa aatttagaaa ggcaattaga caatttaaaa
    23221 acctttggcg ttgaaaaaat atttacagaa aaacaatcag gtcaatctat tgagaataga
    23281 cccatttttc aagaagtatt gaacttcgtg agaatgggag accgttttgt cgtggaatca
    23341 attgatcgtt taggtcgtaa ttatgatgaa gtcattaata ccgttaatta tctaaaggat
    23401 aaagatgtgc aattgatgat tactagcctg ccgatgatga atgaagtgat tggcaatccg
    23461 ttactagata aatttatgaa agatttaatt atacagatat tagctatggt ttcagaacaa
    23521 gaaagaaatg aaagtaaacg tcgacaagct caaggtattc aagttgcaaa agagaaaggc
    23581 gtatataaag gccgcccttt actctattct ccgaatgcga aagatcctca gaaacgtatt
    23641 atctatcatc gtgttgtaga aatgttagaa gaaggtaaag caattagtaa aattgcaaaa
    23701 gaggtgaata taacaaggca aacggtttat cgaattaaac acgataacga tgatttgttt
    23761 taataaactg tttttcgatg caaatgaacg cttctcacag cgtctaaaaa cttataagca
    23821 tcatttatta tgaaatttta ataataagac aagaaaaaat aaggcaaaaa ctggtactag
    23881 tttttgcctt attaatattc aatataaata agtgagttgt acttcatctc aaataaattt
    23941 tatagtttag aaatattata tatcattact tactgtaata tatccctaat ggttataaga
    24001 acaacgctta ctggcttttc taccatgaac tataacatat aatataccag cgataattgc
    24061 aacaatggcc ataattacat ataaaccgtt aaagcctaag aatgggataa agagtcctag
    24121 caatgaaggt gctattccag ccccaccatc aagtaaaata tagaaagtgg aagttgctag
    24181 ccctgctttt accgtaggag cttcttgtac cgcaatcgct tgtccactcg cagtgaatgt
    24241 accatatcca agtcctacaa aaacacctga taataaaata agccaaggcc atacacttgc
    24301 taaactaatt aatagtaaac cgactgccaa gctaataaag gcaggatata atactacatt
    24361 ttcaccttta atatcgaaca attttcctac aaaaggtcga gaaattgctg ttgtcgctgc
    24421 ataaaataag aaaaagaaac tagcaatttg tacagcgtga atagaaactg catatgtatt
    24481 aatgaatgaa ataatacttg cataagctga accgacgagt aatgcgataa atgcaattgg
    24541 taaggcatgt ggttcaaaga aattacttag actaaagccc ttggattttt ctttaaaagc
    24601 aacttctttt ttatcttcta ctaatgcttc gatgcgaggc acatttaaaa ataaagaaag
    24661 tgtaaagctc attactacta atagaataca gaagacaacg ttagcactga atgaataatg
    24721 ctgtgtcact aatgtaccga ttaatggtcc aacgcctgcg ccaagaggag tacttaaagc
    24781 aaaatagcca ataccttcgc cacgtttact ttcgggtaca atgcgcgcaa caatcgctcc
    24841 agtacctgta atagcaacac ctagtgaaaa tccatgtagt aaacgaataa tgtctaatat
    24901 aaatatggat gaagaaaata
//
