LOCUS       NZ_CP120538             9630 bp    DNA     circular CON 20-OCT-2023
DEFINITION  Providencia sp. PROV099 plasmid pPROV099-NR2, complete sequence.
ACCESSION   NZ_CP120538
VERSION     NZ_CP120538.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33762892
            Assembly: GCF_032707925.1
KEYWORDS    RefSeq.
SOURCE      Providencia sp. PROV099
  ORGANISM  Providencia sp. PROV099
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Providencia.
REFERENCE   1  (bases 1 to 9630)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of PROV099
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9630)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-MAR-2023) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology, No.
            20, Dongdajie, Fengtai, Beijing, Beijing 100071, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/18/2023 17:33:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,633
            CDSs (total)                      :: 4,530
            Genes (coding)                    :: 4,461
            CDSs (with protein)               :: 4,461
            Genes (RNA)                       :: 103
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 22 of 69
            Pseudo Genes (incomplete)         :: 52 of 69
            Pseudo Genes (internal stop)      :: 19 of 69
            Pseudo Genes (multiple problems)  :: 15 of 69
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9630
                     /organism="Providencia sp. PROV099"
                     /mol_type="genomic DNA"
                     /strain="PROV099"
                     /host="Homo sapiens"
                     /db_xref="taxon:2949815"
                     /plasmid="pPROV099-NR2"
                     /geo_loc_name="China:Beijing"
     gene            316..936
                     /locus_tag="P3L54_RS23045"
                     /old_locus_tag="P3L54_23030"
     CDS             316..936
                     /locus_tag="P3L54_RS23045"
                     /old_locus_tag="P3L54_23030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008322831.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_210831828.1"
                     /translation="MIISCIGQKGGGAKSTIARTLAVGFTEAGWKTHLADIDEKQQTSL
                     KWCKRREDAGLAVVDCALYRRIETAVKIKDQYHLLIIDGRPAAETTSLDVALESDLVLV
                     STGTTIDDLEPSLELVRELIKKGIDKDKITFIVAKSPSDSEGAKAQETIRAWGFNVLNS
                     IIPFKTSYGNALDLGRALNETSFKSLNLIAKNMIEEVHDIINS"
                     /name="ParA family protein"
     gene            987..1214
                     /locus_tag="P3L54_RS23050"
                     /old_locus_tag="P3L54_23035"
     CDS             987..1214
                     /locus_tag="P3L54_RS23050"
                     /old_locus_tag="P3L54_23035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_096865195.1"
                     /translation="MKAPKSNIKLTPPQDNEPTLDVTGKGAKPDTDIKPIQIKIPVNKH
                     KEMKAYAAEQGISMTEMLLTGYEMYRSKMN"
                     /name="hypothetical protein"
     gene            complement(1366..1860)
                     /locus_tag="P3L54_RS23055"
                     /old_locus_tag="P3L54_23040"
     CDS             complement(1366..1860)
                     /locus_tag="P3L54_RS23055"
                     /old_locus_tag="P3L54_23040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_272663302.1"
                     /translation="MKSLSIIFISLFTLNGCAYYSHQFGLGDHSAFCSNIENDRDRHNE
                     KYYISGSQFFYITKNGDYYSEKEFNQLTSPTLINVSYGGLSAKELKDTAKKVFTVKFTN
                     TNTNKNICSSTLVSSDTYEKNYMDSILGRKLLISSEKGKGASGKEIYRDEGKKSLSIQY
                     F"
                     /name="hypothetical protein"
     gene            complement(1885..2475)
                     /locus_tag="P3L54_RS23060"
                     /old_locus_tag="P3L54_23045"
     CDS             complement(1885..2475)
                     /locus_tag="P3L54_RS23060"
                     /old_locus_tag="P3L54_23045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006710188.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_048609164.1"
                     /translation="MGRIFIYCRCSKVEQDTENQVMAIRNWRAEFKDIPDYRVVNETIS
                     GGVPAMQRPHFANLVNNKLEAGDSLVVLKLDRLGRDNIDIQKTISLLSEKEINLICLDL
                     PIADLMSAEGKLMMQLFASFAEFEKSRIIERTHEGLRKAKAKGVTLGRPKGSSIHKEAI
                     QIAKEAGLSQSKVAKHLGIGIATVKRHWNANKI"
                     /name="recombinase family protein"
     gene            2632..2943
                     /locus_tag="P3L54_RS23065"
                     /old_locus_tag="P3L54_23050"
     CDS             2632..2943
                     /locus_tag="P3L54_RS23065"
                     /old_locus_tag="P3L54_23050"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015353861.1"
                     /translation="MAECPFCKSEVHDEASICRSCGAEKVDSFGGHFNKAFKETQHGVA
                     PLGFVGLLIGGLLGLSVGMNSNGVLGFIVFILILLFFITLPALLRTLLFRRNKTIWYR"
                     /name="hypothetical protein"
     gene            2963..3484
                     /locus_tag="P3L54_RS23070"
                     /old_locus_tag="P3L54_23055"
     CDS             2963..3484
                     /locus_tag="P3L54_RS23070"
                     /old_locus_tag="P3L54_23055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001588079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_048609169.1"
                     /translation="MSKFKCSVLALTVLALSGCGEKSDIENAINKNIENKEYCYSLQDN
                     DISFPITIGRDNFSQDFSPILKGLANQGLVTLHNQGYRDYVISLTEKGAKTDFWDKKRG
                     VCMGKRVVDDIKEWTEGEQNTIMVTYTEKLVDVPRWVDKKSFSDIEGMDSPAEKRAVLK
                     KTSNGWKVWN"
                     /name="hypothetical protein"
     gene            3656..4186
                     /locus_tag="P3L54_RS23075"
                     /old_locus_tag="P3L54_23060"
     CDS             3656..4186
                     /locus_tag="P3L54_RS23075"
                     /old_locus_tag="P3L54_23060"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_272663289.1"
                     /translation="MNYNLPSPEEMIKQLGDLINKRNEKERLGDFFNNDYFSEFRKCIN
                     NEVSEIKNMEVKRSIKGAYLSACIKRYKRNIVKDYILKIALIEGLDLTQRIADLFFIEC
                     LGRSVGEFFLNEHFSGLQYKENKLTKIKRTSENIVLNPVKKEEVKGIIAKYKNQIIDSV
                     EKIKCYFYEAKLY"
                     /name="hypothetical protein"
     gene            4470..4829
                     /gene="mobC"
                     /locus_tag="P3L54_RS23080"
                     /old_locus_tag="P3L54_23065"
     CDS             4470..4829
                     /gene="mobC"
                     /locus_tag="P3L54_RS23080"
                     /old_locus_tag="P3L54_23065"
                     /inference="COORDINATES: protein motif:HMM:NF017524.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_272663290.1"
                     /translation="MEVKKFYKDRYQRKNFVRLCFNDFEFSIVEQIAKDKRKSKATALR
                     EFILDKEIKIKKDIQLTDRSGVYYELHKIGVNINQIAKKMNTDLESFLSGNGEEFAYLM
                     EEIFEYIEYIKNRIN"
                     /name="mobC"
     gene            4832..6244
                     /locus_tag="P3L54_RS23085"
                     /old_locus_tag="P3L54_23070"
     CDS             4832..6244
                     /locus_tag="P3L54_RS23085"
                     /old_locus_tag="P3L54_23070"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_272663292.1"
                     /translation="MYHKIIGGIADRKQRNIKNAVNYLLRLNKSEEQIHVKTLSMTSQQ
                     DLLNFNNFILPKNKKSPYVCGVLSFEEENINEDLKVKIMTDFEEMLFSGIELTNRPPLM
                     WVQHTDKGRLELNYLTFNVLADGRSFTAYFDKTDRKLFNTFSEIINYENDFSSPLEKLD
                     KRNTLINNPNPQAPKDKKLLIENLNNEIMGQILIGELADRNEVIKYIKSKGYKINRVRK
                     NAISIKLENDDKPIVLKGDIYEEGRIYADYRREPEVSNRRDPEVVKSALNQFRDDFERL
                     LSKRQDKNRKRFKSSQRSIEKRIESRVNSQYLDQNFEVKNSFGVGGVTFSKSNLYHDIN
                     HNNNFKIKEKNSELYIGTYKRKEKTEAERFELLRNRILEAKRVQKSTDHGIERFRDQQH
                     RIRDSIRTTQYRTRFVRGYVARFSELFNEILQRAFSFSFRAKTLEERKEKAKILQKEKT
                     AELKSSGRKFRV"
                     /name="hypothetical protein"
     gene            complement(6367..6891)
                     /locus_tag="P3L54_RS23090"
                     /old_locus_tag="P3L54_23075"
     CDS             complement(6367..6891)
                     /locus_tag="P3L54_RS23090"
                     /old_locus_tag="P3L54_23075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_272663294.1"
                     /translation="MTLKPNKDYEKLLHLWPAIQEYQNLANEHGIYDIFQDNGGKLLQV
                     LLLLDIKVLPGREGNDAIDSSGIEYELKSANIDLVKNFSTHHHMNPKIIEKYRKVPWVF
                     AIYENIEIKSIYILQPENLEFFYDKWEKKWHSDGGKDINNPKIPIKYVIENGDLYFGSP
                     PDLSKPRSKKL"
                     /name="restriction endonuclease"
     gene            complement(6872..7102)
                     /locus_tag="P3L54_RS23095"
                     /old_locus_tag="P3L54_23080"
     CDS             complement(6872..7102)
                     /locus_tag="P3L54_RS23095"
                     /old_locus_tag="P3L54_23080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004698325.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_272663295.1"
                     /translation="MMLREILAKNIKNHRNKNNISQESFADLVGLHRTYIGAVERSERN
                     ISIDNIEKIAKAMKISASDLLKEEFNDSETK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            7182..8159
                     /locus_tag="P3L54_RS23100"
                     /old_locus_tag="P3L54_23085"
     CDS             7182..8159
                     /locus_tag="P3L54_RS23100"
                     /old_locus_tag="P3L54_23085"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009029636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0008170 - N-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="WP_272663297.1"
                     /translation="MIDDLKRAYYTNNGAVYEGDSLKLLDSIADNSINLIITSPPFALQ
                     RKKEYGNHDQDDYIDWFIPFAEKAKRKLTDDGSFVIDFGGAYKKGMPVRSLYNFKILIE
                     LVETVGFHLAEDFYWFNPSKLPSPIEWVNKRKLRVKDSVNTIWWLSKTPWPKSDVTKVL
                     SPYSEKMKKLIDNPEKYYTPKMRPSGHDIGSSFGKDNGGAIPPNLLQIPNSESNSGYLS
                     GCKKVGVKSHPARFPAKLPEFFIKMLTDENDIVLDIFGGSNTTGMVAENLNRKWITFEK
                     EINYIATSAFRFFDKGENEESLIKVHDDILSGNEVKLNEFLVKK"
                     /name="site-specific DNA-methyltransferase"
     gene            complement(8203..8466)
                     /locus_tag="P3L54_RS23105"
                     /old_locus_tag="P3L54_23090"
     CDS             complement(8203..8466)
                     /locus_tag="P3L54_RS23105"
                     /old_locus_tag="P3L54_23090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein"
                     /protein_id="WP_272663298.1"
                     /translation="MKIKNQKRNTKAKDLAFEYGVSIATVKKYYSQDREDYEQEAAARR
                     KQAFELRQKGLAWKDVADSMNATIDAVKSLAKRYKQQDKNQI"
                     /name="plasmid replication protein"
     gene            complement(8463..9317)
                     /locus_tag="P3L54_RS23110"
                     /old_locus_tag="P3L54_23095"
     CDS             complement(8463..9317)
                     /locus_tag="P3L54_RS23110"
                     /old_locus_tag="P3L54_23095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_272663300.1"
                     /translation="MYNDNQETIISQLPYKPYCSDNLDYGLKIRPKNKALDMLYLQINN
                     PSIQTCLLFDIDRDNSFYDFEEAHLPVPHFTTQNPENGRCHMGYILKRGVCKTQNAKLE
                     PLRYAAAVELEMGKNLKADQGFAGLITKNPFNPHWRPHWSNADLYELDYLADFITLENS
                     NKETTKYESFGLGRNVNLFDDLRHYAYKNVLKFKEISDFHHWMNEIEKQAINLNTYSNP
                     TNLLPFNEIKATARSVGKWVWKNFSSEQFSKIQSERGKRNLGKTKTKKKAANLLAALRN
                     ELL"
                     /name="replication initiation protein"
     Typing          complement(8464..9317)
                     /name="rep_cluster_1478"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.854"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4833..6241
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.34"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tctaaatgtt cttatatctg tagtggacat ttattttatc taattgagcg agatccgaaa
       61 gagatcctga tttagaacct tcgttatgtt tcctctatct agtttttcgg cgttttttat
      121 attcaccctt tacgattact caaaactcaa tcaagcgcgt tatacgacgt ttaacgtatg
      181 gtgataaaaa ttagttaata tttttattga atgagactta tcattaaatc atgatagcat
      241 gaagttttat tttaatctca atctaaatat ggcaatataa ccaactacaa catgaaataa
      301 tgaaagagtg aaatcatgat aatttcttgc attggtcaga aaggtggtgg tgcaaaaagc
      361 actatagcca gaacgttagc cgtaggtttt actgaagccg gttggaaaac tcaccttgca
      421 gatattgacg aaaaacagca aacctctttg aagtggtgca aaagaagaga agatgccggc
      481 ttagctgttg ttgattgtgc attatatcgg cgaattgaaa ctgcagttaa aataaaagat
      541 caatatcatt tgctaattat cgatggaaga cctgcagcgg agacgacttc gttagacgta
      601 gctctcgagt cagaccttgt tctggtttct actggaacaa caattgacga cttagagcca
      661 tcattagagt tagtgagaga gctgatcaaa aagggaatag ataaagataa gattactttt
      721 attgttgcta aatccccgtc tgacagtgaa ggcgctaagg ctcaagaaac cataagggct
      781 tggggcttta atgtgcttaa ttcaataatt ccttttaaaa cgagctacgg aaacgcactt
      841 gatctaggta gagcattgaa tgaaacctcg tttaagtcat taaatcttat tgctaaaaat
      901 atgattgaag aagttcatga tataattaat tcatgatatc atgaattggt attgtgaata
      961 aaattgatta attagtagag gtgagaatga aagcgccaaa aagtaatatc aaattaacac
     1021 caccacaaga taatgagcca acccttgacg tgacagggaa aggagcaaaa cctgatacag
     1081 atatcaagcc tattcaaata aaaattcctg ttaacaaaca taaagaaatg aaagcgtatg
     1141 ctgcagagca ggggatctca atgacagaaa tgttattgac tggatatgaa atgtatcgaa
     1201 gtaaaatgaa ttaatgaaat catgatttca ttaatttgtt tgtgttatat caaatagtta
     1261 gttggatttt taattgtttg ttatttttac attcagtatt ttcttatttg aatattttgt
     1321 atttcagtaa taaaatgcca gtatcaaaaa ccgaacggtt attatttaaa aatattgaat
     1381 tgaaaggctt tttttgcctt catctcgata aatctctttt ccagaagctc ccttaccttt
     1441 ctcgcttgaa ataagaagtt ttctacctaa aatggaatcc atatagtttt tttcataagt
     1501 atcagagcta actagtgttg aagaacaaat atttttgttt gtattcgtat ttgtgaattt
     1561 aacagtgaag acttttttgg ctgtgtcttt tagctcttta gcagatagcc caccatagga
     1621 aacattgatc agtgttggag aggtcaattg gttgaactct ttttcagagt agtaatcacc
     1681 gttctttgtg atatagaaaa attgagagcc actaatgtaa tatttttcgt tatgtcgatc
     1741 tctatcattt tctatattag aacaaaaagc ggaatggtca cctaacccga actggtgaga
     1801 gtaatatgca cagccattta acgtaaataa tgatatgaat atgattgata atgatttcat
     1861 gctaaatatt actctttgaa ttatttaaat tttattagcg ttccagtgtc tttttactgt
     1921 tgctatacca atacctaaat gctttgctac tttgctttgg cttaaacctg cttctttggc
     1981 tatttgtata gcttctttat gaatgcttga ccctttaggc ctccccagtg tgacgccttt
     2041 cgctttggct tttcttaatc cttcatgtgt tctctcgata atccgagatt tttcaaattc
     2101 agcaaaagag gcaaaaagtt gcatcattaa tttaccttct gcagacatga gatcggctat
     2161 tggtaaatcg agacaaatta ggtttatttc tttctcactt aataagctta tcgttttttg
     2221 aatatcgata ttatctcttc ctaagcgatc taatttcaaa acaactaacg agtcacccgc
     2281 ttccagctta ttgttaacca agttagcaaa atggggacgt tgcattgcag gaacaccacc
     2341 actaatagtc tcattcacaa ccctataatc tggaatatct ttaaattctg ctctccaatt
     2401 acgtattgcc ataacttggt tttctgtatc ttgttctacc tttgaacacc tacaataaat
     2461 aaaaattcta cccataactt tatcctccta agaatcatta atcggtatca taatgtttta
     2521 aggtatcaat aagttatgtc aatgcttttg tagcgaataa agttacctat atccctaata
     2581 tcaataaccg ttcggttttt gataccgtaa aaatacttag ggggaatagg tatggctgag
     2641 tgtccatttt gtaaatcaga ggttcatgat gaagcttcga tatgtcgaag ctgtggagct
     2701 gaaaaagttg actcattcgg ggggcacttt aataaagcat ttaaagagac tcaacatgga
     2761 gtagcgccat taggttttgt aggattgctt attggggggc ttttggggct ttcagtcggc
     2821 atgaattcaa atggtgttct aggttttatt gtattcatac ttattctttt attttttata
     2881 acgctccctg ctttattaag aacactactt tttagaagaa ataagacaat ttggtataga
     2941 taacttataa ataggaataa ttatgtctaa gtttaaatgt tcagtattag ctttaacggt
     3001 attagctttg tctggttgtg gtgagaaaag cgacatagag aacgcgataa ataaaaacat
     3061 agaaaataag gagtattgtt atagcctaca agataatgat atttcatttc ctatcacaat
     3121 aggacgagat aacttttctc aagatttttc acctatttta aaaggattag ctaatcaagg
     3181 gttagtaact ttacataatc aaggttatag ggattatgtt ataagcttaa ccgaaaaggg
     3241 ggctaaaaca gatttttggg ataaaaaacg tggtgtgtgt atggggaaac gggttgttga
     3301 cgatataaaa gagtggactg aaggtgagca aaatacaatc atggtcacat atacagagaa
     3361 attagttgat gttcctcgtt gggtagataa aaagtctttc tctgatattg aaggaatgga
     3421 tagccctgca gagaaacgtg ctgttttaaa aaaaacaagt aatggttgga aagtttggaa
     3481 ttaatataaa actttttcaa aaaaacacag aaagcagaca aaacaagttt tgcctgcttt
     3541 ctgtgttgtc ataactaaat ttaatagtat tcgatagata aaaatttgac attacctttt
     3601 tatgtattat ttatattgct aaataatcga ttaaataact ataaagaggt ttataatgaa
     3661 ttataattta ccaagcccag aggaaatgat taaacaatta ggtgatttaa ttaataaaag
     3721 gaatgaaaaa gagaggttgg gagatttttt caataatgat tatttttctg agttcagaaa
     3781 atgtataaac aatgaagttt ctgaaataaa aaacatggag gttaaaaggt caataaaagg
     3841 tgcatattta agcgcttgta taaaaagata caaaaggaac atagtaaaag actacatact
     3901 taaaatagcg cttattgagg ggttagacct gactcagagg atagcagatc tattttttat
     3961 tgaatgccta ggaagaagtg tgggagagtt ctttctcaat gagcattttt ctgggttgca
     4021 atataaagaa aataaattaa ctaaaataaa aagaacgagt gaaaatattg tattaaatcc
     4081 agtaaaaaaa gaagaagtaa aaggaattat agcaaaatat aaaaatcaaa ttatcgactc
     4141 agtagaaaaa ataaaatgtt atttttacga agctaagctt tattgaaata ctattgctat
     4201 ttaatcgact atataacttt tagtatctaa gctaattaat cgattaattg atattaataa
     4261 ctaaagctaa ataatcgatt aattagcttt aaatgtaaat atttgacttt tattttattt
     4321 gttttattta ctttatatgt gagagagcaa gctcagacaa tactgcgtat tgtcgcttgt
     4381 gaggggttgg cttcgccctc cccttcaatc cccacccaag ggcggaaaaa ctaaaagaaa
     4441 aaatcaaaac ctaatcggag gtgttattta tggaagtgaa aaagttttac aaagatcgct
     4501 atcagagaaa aaattttgtg cgtttatgtt ttaatgattt cgagttttct attgttgaac
     4561 aaatcgcaaa agataaaagg aaaagcaaag ctaccgcatt gcgtgaattt attctcgata
     4621 aagaaataaa aattaaaaaa gatattcagt taacagatcg atctggtgtt tattatgaat
     4681 tacacaaaat tggtgtgaac ataaaccaaa ttgctaaaaa aatgaataca gatttggaat
     4741 catttttatc tggtaatggt gaggaattcg cttatttaat ggaggaaatc ttcgaatata
     4801 ttgaatatat aaagaacagg ataaattaat tatgtatcat aaaattatag gcgggatagc
     4861 agatagaaaa caacgaaata taaaaaatgc ggttaattat ttattaaggc taaataaatc
     4921 agaagagcag atacacgtta aaacgctctc tatgacgtca caacaagact tattaaattt
     4981 taataacttc atattaccaa agaataaaaa atcgccctac gtgtgtggcg tgctctcatt
     5041 tgaagaagaa aacataaatg aagacttaaa agttaaaatt atgactgatt ttgaagaaat
     5101 gcttttttca gggatagaac taacgaatag accacctctc atgtgggtgc agcataccga
     5161 caagggtagg ttagaactta attatttaac atttaatgta ttagctgatg gtcgttcttt
     5221 tactgcttac tttgataaga ctgatagaaa attattcaac acattttctg agatcataaa
     5281 ttatgaaaat gatttttcta gcccactgga gaagttagat aaaagaaaca cattaataaa
     5341 taacccaaat cctcaagccc ccaaagataa aaagcttctt attgaaaacc ttaacaatga
     5401 aattatgggg caaattttga ttggcgaatt agcagatcgt aacgaagtaa taaaatacat
     5461 aaaatcaaaa ggttataaaa taaatagagt aagaaaaaat gcgataagta taaagttaga
     5521 aaatgacgat aaacccattg ttttgaaagg agatatttat gaagagggta gaatatacgc
     5581 agattataga agagagccag aagttagcaa tagaagagat ccagaagttg ttaaaagcgc
     5641 actcaatcaa tttagagacg actttgagcg attgcttagc aaacgacaag ataaaaatag
     5701 aaaacgcttt aaaagctcac agagaagcat tgagaaaaga attgagagca gagttaacag
     5761 ccaatatttg gatcaaaatt ttgaagttaa aaattcattt ggggttgggg gcgttacttt
     5821 ctctaagtct aatttatatc acgatattaa ccataataat aattttaaaa taaaggagaa
     5881 aaacagtgag ttatatattg gaacgtataa gagaaaagaa aaaacagaag cagaaagatt
     5941 tgaattatta cgaaatagaa tacttgaagc taaacgagtc cagaaatcaa ctgatcatgg
     6001 aattgagaga tttagagatc agcagcatag aattcgagac tcaattagaa ctactcaata
     6061 cagaactcga tttgttagag gatacgttgc tagatttagt gaattattta acgaaatctt
     6121 gcaaagagct ttcagcttta gtttcagagc taaaaccctc gaagagcgca aagaaaaagc
     6181 aaaaatcctc caaaaagaaa aaacggccga actcaaaagt tcaggaagaa agtttagagt
     6241 ctgatattga aaatattaag cgtatggttg attttttaat gtcagaatat aaaaaatcta
     6301 tagaaaaaaa tagaaaggct agaaactagc ctttctattt aagctatttt cctgagtaaa
     6361 aaaaacttat aactttttac ttctaggttt tgacaagtct ggaggcgaac caaaatataa
     6421 atcaccattt tctattacgt attttattgg tatttttggg ttattgatat cttttcctcc
     6481 atctgaatgc catttttttt cccatttatc ataaaaaaat tctagatttt caggctgtaa
     6541 aatatatatg ctttttattt ctatgttttc gtaaattgca aaaacccaag gaacttttct
     6601 gtatttttct attatttttg gattcatatg gtggtgtgtt gaaaagtttt tcactagatc
     6661 aatatttgct gattttaatt catattcaat accacttgag tcaattgcat catttccctc
     6721 tcttccgggg agtactttta tgtctagtaa taataatact tgtaataatt ttcctccatt
     6781 gtcttgaaat atatcatata ttccatgctc attagctaga ttttggtatt cttggatagc
     6841 aggccataaa tgtagtagtt tttcgtagtc tttatttggt ttcagagtca ttaaattctt
     6901 cctttaacaa atctgatgct gatattttca tcgcttttgc aattttttca atattatcaa
     6961 tagatatatt tctttctgac cgctctacag ctccaatgta tgtgcggtgt aagccaacaa
     7021 ggtctgcgaa agattcttgt gatatattgt ttttatttct atgattttta atgtttttag
     7081 cgagtatttc tcgtagcatc atcttcattt tcattgaata ataaaggaat aaaatgtact
     7141 atttgatgac tatatatcta cagactatga gtagcagatt gatgattgat gatttaaagc
     7201 gtgcatatta tacgaataat ggagcggtat atgaggggga ctctctgaag ttattagatt
     7261 ctatcgctga taatagtata aatctaatta ttacaagtcc gccttttgct ttgcagcgta
     7321 aaaaagaata tgggaatcat gatcaagatg actatataga ttggtttatc ccttttgctg
     7381 aaaaagcaaa gagaaaatta actgatgatg gtagttttgt tatagatttt ggtggtgctt
     7441 ataaaaaagg tatgccagta agaagtttat ataattttaa aattctaatt gaattagttg
     7501 aaacggttgg ctttcatttg gctgaggatt tttattggtt taatccatca aaactaccaa
     7561 gtcctattga atgggtaaat aaaagaaaac taagggtaaa ggattcagta aatactattt
     7621 ggtggttaag taaaactcca tggcctaaat cagatgtaac aaaagtattg agtccatata
     7681 gtgaaaaaat gaaaaagcta attgataatc ctgaaaaata ttatacacct aagatgagac
     7741 cgtcaggaca tgatattgga agtagctttg gtaaagacaa tggtggtgct atccctccga
     7801 atttacttca aatcccaaat tcagaatcaa atagtggata tttatcaggt tgtaaaaaag
     7861 taggagttaa atcgcaccca gcaagattcc ctgctaagtt gcctgagttt tttatcaaaa
     7921 tgcttacaga cgaaaatgat attgttcttg atatttttgg tggttcaaat actacaggaa
     7981 tggttgcaga aaatctaaat aggaaatgga ttacttttga gaaagagatt aattatatag
     8041 caacatcagc tttcagattc tttgataaag gtgaaaatga ggaatctctc ataaaagttc
     8101 atgatgatat cctttctgga aatgaagtta agttaaatga gtttttagta aaaaaataat
     8161 ttaataaaaa gagaatttta ttagaataaa ttctctttta ttttaaattt ggtttttatc
     8221 ttgctgcttg tagcgctttg ctaaggattt taccgcatca attgtagcgt tcatgctatc
     8281 agcaacgtct ttccaggcta agcctttctg tctaagttca aacgcttgtt ttctacgggc
     8341 tgcagcttct tgttcgtaat cttcacgatc ctgtgaatag tattttttta ctgttgcgat
     8401 tgatacgcca tattcaaatg ctaaatcttt tgcttttgtg tttctttttt gatttttaat
     8461 tttcatagta attcattcct tagtgcagcg agtagattag cagctttttt cttcgtctta
     8521 gtcttcccta ggtttctttt tcctcgctca ctttgtattt ttgaaaattg ttcggagcta
     8581 aaattcttcc atacccactt tccaacgctt cttgctgttg ctttaatttc gttaaaaggt
     8641 aataaattag tcggatttga ataagtattg agattaattg cttgtttttc gatttcattc
     8701 atccagtgat gaaaatcgct gatttcttta aattttaaaa catttttata agcataatgt
     8761 cttaagtcgt caaagaggtt gacgttgcga cctaatccaa agctttcata cttagtggtc
     8821 tctttatttg agttttctag tgtaatgaaa tcagctaaat aatcgagttc atataaatcc
     8881 gcattgctcc aatgaggtct ccagtgtgga ttgaatgggt ttttagtgat taaacctgca
     8941 aatccctgat ctgcttttag attttttccc atttctaatt caactgcagc cgcataacgt
     9001 aatggttcta actttgcatt ttgagtctta catactcctc tttttagtat atatcccata
     9061 tgacaacgcc cgttttctgg gttttgagtt gtaaaatgag gaactgggag gtgtgcttct
     9121 tcaaaatcat aaaagctgtt atctctatct atatcaaaca ataagcatgt ttgaattgaa
     9181 ggattattta tctgtaagta aagcatatct aacgctttat ttttaggtct tatttttagc
     9241 ccgtaatcta ggttatcact acaatatggc ttatagggaa gttgactaat tattgtttct
     9301 tggttatcgt tatacatgaa taaacaattc cttgtagttg aaaccctgca cttaagtttg
     9361 ccgaccagag tgtggggttt tgttttttat aagttataac tccttttttc tttgtgtcaa
     9421 gtgtctaaat taaccatatc agataacagc caatttttgg tgggttttca tattcaaaag
     9481 gaaaactgtt tatttagatt attgaacgtg tcaagtgtct aaattaacca tatcagataa
     9541 cagccggatc tcttgggggg ttttagatca taggaaagta atgctattta tcaaaacgga
     9601 ctgatttctc agcccttttc ttcatattgt
//
