LOCUS       NZ_CP120037            20730 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Staphylococcus aureus strain Dog138 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP120037
VERSION     NZ_CP120037.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33696823
            Assembly: GCF_034043215.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Canine Staphylococcaceae circulating in a Kenyan animal shelter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
  REMARK    Annotation added by database at the submitter's request
REFERENCE   3  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Flye v. v2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 286x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/06/2024 10:54:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,726
            CDSs (total)                      :: 2,644
            Genes (coding)                    :: 2,580
            CDSs (with protein)               :: 2,580
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 32 of 64
            Pseudo Genes (internal stop)      :: 18 of 64
            Pseudo Genes (multiple problems)  :: 17 of 64
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Dog138"
                     /isolation_source="nasal swab"
                     /host="Canis lupus familiaris"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="Kenya:Nairobi"
                     /lat_lon="1.3345 S 36.7331 E"
                     /collection_date="2015-06-27"
                     /collected_by="Joerg Jores, Anna Lacasta, Anne Liljander,
                     Paul Ssajjakambwe (International Livestock Research
                     Institute, ILRI)"
     gene            complement(108..923)
                     /locus_tag="P3U31_RS13515"
                     /old_locus_tag="P3U31_13515"
     CDS             complement(108..923)
                     /locus_tag="P3U31_RS13515"
                     /old_locus_tag="P3U31_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(916..2359)
                     /locus_tag="P3U31_RS13520"
                     /old_locus_tag="P3U31_13520"
                     /pseudo=""
     CDS             complement(916..2359)
                     /locus_tag="P3U31_RS13520"
                     /old_locus_tag="P3U31_13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(2331..2924)
                     /locus_tag="P3U31_RS13525"
                     /old_locus_tag="P3U31_13525"
     CDS             complement(2331..2924)
                     /locus_tag="P3U31_RS13525"
                     /old_locus_tag="P3U31_13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(3188..3568)
                     /gene="blaI"
                     /locus_tag="P3U31_RS13530"
                     /old_locus_tag="P3U31_13530"
     ARG             complement(3192..3568)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(3558..5315)
                     /gene="blaR1"
                     /locus_tag="P3U31_RS13535"
                     /old_locus_tag="P3U31_13535"
     ARG             complement(3562..5315)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            5422..6267
                     /gene="blaZ"
                     /locus_tag="P3U31_RS13540"
                     /old_locus_tag="P3U31_13540"
     ARG             5423..6264
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6636..7244
                     /locus_tag="P3U31_RS13545"
                     /old_locus_tag="P3U31_13545"
     CDS             6636..7244
                     /locus_tag="P3U31_RS13545"
                     /old_locus_tag="P3U31_13545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            7658..7951
                     /locus_tag="P3U31_RS13550"
                     /old_locus_tag="P3U31_13550"
     CDS             7658..7951
                     /locus_tag="P3U31_RS13550"
                     /old_locus_tag="P3U31_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            8026..9960
                     /locus_tag="P3U31_RS13555"
                     /old_locus_tag="P3U31_13555"
     CDS             8026..9960
                     /locus_tag="P3U31_RS13555"
                     /old_locus_tag="P3U31_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            9964..10275
                     /locus_tag="P3U31_RS13560"
                     /old_locus_tag="P3U31_13560"
     CDS             9964..10275
                     /locus_tag="P3U31_RS13560"
                     /old_locus_tag="P3U31_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            10287..10913
                     /locus_tag="P3U31_RS13565"
                     /old_locus_tag="P3U31_13565"
     CDS             10287..10913
                     /locus_tag="P3U31_RS13565"
                     /old_locus_tag="P3U31_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            11151..11780
                     /gene="mobV"
                     /locus_tag="P3U31_RS13570"
                     /old_locus_tag="P3U31_13570"
                     /pseudo=""
     CDS             11151..11780
                     /gene="mobV"
                     /locus_tag="P3U31_RS13570"
                     /old_locus_tag="P3U31_13570"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            11874..12419
                     /locus_tag="P3U31_RS13575"
                     /old_locus_tag="P3U31_13575"
     CDS             11874..12419
                     /locus_tag="P3U31_RS13575"
                     /old_locus_tag="P3U31_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            12803..13663
                     /locus_tag="P3U31_RS13580"
                     /old_locus_tag="P3U31_13580"
     CDS             12803..13663
                     /locus_tag="P3U31_RS13580"
                     /old_locus_tag="P3U31_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_054105168.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNIFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="RepB family plasmid replication initiator protein"
     gene            13750..14091
                     /locus_tag="P3U31_RS13585"
                     /old_locus_tag="P3U31_13585"
     CDS             13750..14091
                     /locus_tag="P3U31_RS13585"
                     /old_locus_tag="P3U31_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(14330..14401)
                     /locus_tag="P3U31_RS13590"
                     /old_locus_tag="P3U31_13590"
     CDS             complement(14330..14401)
                     /locus_tag="P3U31_RS13590"
                     /old_locus_tag="P3U31_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            14550..14735
                     /locus_tag="P3U31_RS13595"
                     /old_locus_tag="P3U31_13595"
     CDS             14550..14735
                     /locus_tag="P3U31_RS13595"
                     /old_locus_tag="P3U31_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(14954..15697)
                     /locus_tag="P3U31_RS13600"
                     /old_locus_tag="P3U31_13600"
     CDS             complement(14954..15697)
                     /locus_tag="P3U31_RS13600"
                     /old_locus_tag="P3U31_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            16108..16784
                     /locus_tag="P3U31_RS13605"
                     /old_locus_tag="P3U31_13605"
                     /pseudo=""
     CDS             16108..16784
                     /locus_tag="P3U31_RS13605"
                     /old_locus_tag="P3U31_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <16795..17077
                     /locus_tag="P3U31_RS13610"
                     /old_locus_tag="P3U31_13610"
                     /pseudo=""
     CDS             <16795..17077
                     /locus_tag="P3U31_RS13610"
                     /old_locus_tag="P3U31_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            18288..18905
                     /gene="cadD"
                     /locus_tag="P3U31_RS13615"
                     /old_locus_tag="P3U31_13615"
     ARG             18289..18902
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            18924..19271
                     /locus_tag="P3U31_RS13620"
                     /old_locus_tag="P3U31_13620"
     CDS             18924..19271
                     /locus_tag="P3U31_RS13620"
                     /old_locus_tag="P3U31_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            19440..19532
                     /locus_tag="P3U31_RS13625"
                     /old_locus_tag="P3U31_13625"
     CDS             19440..19532
                     /locus_tag="P3U31_RS13625"
                     /old_locus_tag="P3U31_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19744..20718
                     /locus_tag="P3U31_RS13630"
                     /old_locus_tag="P3U31_13630"
     CDS             19744..20718
                     /locus_tag="P3U31_RS13630"
                     /old_locus_tag="P3U31_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     ARG             5423..6267
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          17135..17282
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          12804..13663
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(14955..15697)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11152..11426
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ctaatcatac atatataatt gttgtcactt tactcgatat atgagaatga ctttacctaa
       61 taaatgagaa aagcaacgca ctatattaaa atgcgttgct ttttctatta tcgaatacct
      121 ataactaaac tatctctagc tgtttctaca acttctgtac ttattttatc taaaccattt
      181 atatccataa ttctgtctat ctgcgcaaat aaacgatgaa tcagcctaaa attccctttt
      241 gtaattttaa taatcgtcgt tattgcctca taatcagtaa agtcttcgag ttttaaatca
      301 aatcctaagt cttgccactt atattctaat atatgatgcg tctcatcttt acttagatta
      361 tcaaattcat gcgcaaaacc tatacgcgaa tatagttgag gataacgaga tagttttttc
      421 tctatacccg gcataccaat aaatatcatt gctaaattat gttcatcata aatagctctt
      481 aattgctcta aatgttgcac tttaaggcga tcaatctcat ctactataat taaatcaata
      541 tatttaaaca tatcactata atgtttacta tgttcatgtc catacttatt tacaacatgt
      601 aatttttgac ccaaatcaat gattgcagta atactatata aatcattcct taatttagtt
      661 tgtttttctg ctggtgcatt ataaaatatt ttatccaccg atagtatgtc atcggtcgtt
      721 ttactagcta aatcttccca acctctatgg ttaacttgtt tttcaatagt atcccaattt
      781 gtgtaatacc tagacgataa agtttttccg acaccaggtt gaccataaca tataccaata
      841 tactgatatt taatacaagc atcacaaaat tcagcaaagc gtttatactc tttcgtttca
      901 atgaaatttt gatttttagt cattacgata tctctttaat tttttgacgt ttttagtcgt
      961 ttcttgaggt gaataaccac aatttttttc ttccttaatt aattccgtgg tacttggact
     1021 agcaatattt tgttttaagt gttttcttct ctgactacga gcgtgctgta tgtcttttat
     1081 atctatggag taatcagcta tttctggaca tatagcagta caaagaaatt catctctata
     1141 aaacacacgt atttcagcca tatcatttgg gttataacga atcagtacat attcacctac
     1201 ataagcttct agattagtat tactgtatcg aaaaccttga aaatgaatgc catctgaatg
     1261 aacttttcta gatttaggta tttccaacaa taataaatca agttgttcta agctacttgg
     1321 catattaggg aaaaagtgat tactattcca atgactgata ggcgtggtat gaatagtact
     1381 atgttctttt tgattataat cttcaattaa aaagtaacgt aatttttctt caaaattgtg
     1441 aaaatttatt agattactag gagtatcatt attgtttata tatccaggca gttgttctaa
     1501 gaaagtttga ttaactgtct gaaagaatcg ttctattttt ccacgaccac gaggaacacc
     1561 aactttcgaa aacatcaagt taattttcaa atcaatagcg acttgttcca tatgatgtga
     1621 agtaaagtca cttccatgat ctgtgtagaa tttttcgggt ataccacaca ctggccaatt
     1681 ggtatcattt ttattccata ttgcttggtg tagtgttaat gctgtgtttt gagcattggg
     1741 gggcatcaaa acttaagaaa tagcctgcaa ttgcacgact atagtcatcc ataataatag
     1801 ttagccatgg tctattgata ttaccttttt ggtctaatat aaagatatct agcaaagtat
     1861 ggtctgcttg ccatatttca ttgggtctcg aggattctct aatttgtatt aaatcgtact
     1921 tattttgata gtatttttca ccctgatgag agaaatcaat aacagactta ggcatcgctt
     1981 taataacact ataaatttgt ttataacttg gtatatcaaa attattttct ttacagtaat
     2041 tagtgatttt cctatgaatt gtggctatac tatttctttt attcataagc gcaaggcgtt
     2101 caatttcatc aattatcttt ggttctattt tacgtgttcc tttatcagct cttgtcgcat
     2161 agattagtcc tttaagtcct tgttctttat atgacttatt ccacctataa agggtgctta
     2221 acgcaatccc tttactttta gaaatacttg ataaagattg ttcgcctagg ataaaaggtt
     2281 ttataatatt gtacttttga gtagcttttt tacgtttggc ttcagaaaaa ttagttagat
     2341 acttctcctt gtttttcatc ttccttgtcc tccaatttat tgaggtaacg ataaattgtt
     2401 gtacgtgaaa catgccactg ttctgcaatt gtcttaattg gcgtgccatt atcataaagg
     2461 gtcttaagta agtttaaatc tttttgattt aatttttctg gtctgcctcc atatcggcct
     2521 ctagcacgtg ctgcaattcg gccagctgaa gaacgctcta aaattaaatt acgttcaaat
     2581 tctgcaaatg ctgcgaataa atgaaataat aattgtccag ttgaacttga tttatccatt
     2641 gttatatttt cttctaaact atggaaactt acacctcgtt cgttaagctc attaactaat
     2701 gtgattaaat cctccatatt acgtcccaat ctatctaatc tccaaacaac aatcgtatct
     2761 cctgacctcg caaattcaat tgctttatct aaaccaggtc ttttactttt tgaaccactc
     2821 atatggtcat taaatatctt ttcacaacca tatgtattta atcgatcctc ctgtaaattt
     2881 aaattttgta atccagttga aactcttgca taacctattt tcaaaataca aacctcctat
     2941 atacatcttc agtgtaccat aacttaatta caaggtcttt tatgaacata gattttttgt
     3001 tgggtttttg aacacataat cctatgtaat tcttacttat ttagacataa aagaagagtg
     3061 tacagaaaat ggttattttc tgtacactct catctttaat aatatatttt aaatgtcatt
     3121 aacaaaacta atttaataag agtcaagcat agtttacata tgtattatgt ttgaaacata
     3181 cctctaatta ctttttacta atatcattta aaatatctcg caattcttca atttctttgt
     3241 tatttaattc ttcatttttc gcaaaattca acactaaact tttcatatcc cctccataca
     3301 gtttattaag aaaggtttta gcagttttca ttttaatatc gtcttcttta atatttgatg
     3361 agtaaaaata aatattttct gatttgtatc gttttataat ctctttttta tatagtcttg
     3421 tgattaatgt tctaatcgtt ttatcactaa cttctttata tttttgaatt tcaactacaa
     3481 tttcattagc tgatactgat tttttatccc atattatatt cataacatcc cattcagcca
     3541 tagatatttc aacttgctta ttggccattt aaaacaccca ttccttttaa tattttttca
     3601 cttattaatt cagcattttt cccagacggg tttccatctg ataaatgtgt agcaaaataa
     3661 tacttatcat gatttgtaat tacgtaacct acaaaccacc cattattata cttcccgttt
     3721 actatacctg tacctgtttt cccatacagt tcatactttt catttttctt aatcaataat
     3781 gaagaagata attgattctt tgctttttta ctaaaatggt tattttgttc catcatattt
     3841 ttaaaaacta ttacttgttc aagattagat attttcaaac tatcttccat ccaatagctt
     3901 ttataacttc ccaaattttc attaccataa tttaattgct tgagttgagc cgcagtatag
     3961 ttctttggta tttgattact aatacgttcg aagtaccaat taactgaatt ttgcattgct
     4021 gtatttaaat cttgttcctt attccaagac tcgaaaagat aatgtttatg attccatgac
     4081 atacgtgaat ttttatcact tataatatga cggtcaagtc caaacagtgc taaataaatt
     4141 ttgtaagttg aatcaggaga atatcttttt ctactttctt tttcattata aatatagtat
     4201 ttgtctttct tcatgctgta cataacgaaa gatccactat ttgaaccaaa atttttactt
     4261 tcatctaaaa tttggtaatc gctttgtaag ggctttttat aattataatc agttaaggat
     4321 tgccccatta aaaactggct ttgaattatc atgataaaaa aagtaaaaat acaaataaaa
     4381 attagaatta attttgactg ctttttcaga tcggcttctt ttatattaat taatctattt
     4441 ttgagtaatg attttttacc attaaatgaa tggcttaata tatttttgtt gaaaaatgag
     4501 gtttttaata cggagtccat aatagattcc gcataagttt taaattcatt tttgttaata
     4561 ttattaagga caaatctatc ggcttctact tcattgtcat gaattatctt tctttttaca
     4621 atatgtacta atggattgta actcataata atagagaaga tattaaagat aattaaatgt
     4681 aaagtatctc tatttttagc atgagcatat tcatgcagta ttatatattt tagtctttta
     4741 tcaattacac ttttaaaata tgaactagga atcaaaataa tatatttccc ataccaaaaa
     4801 gttattggag attgaatagc ctctgctttt cgaatcacaa tatttttttt atattgatgg
     4861 ttgaaaagta tcgtatctat tttatttttt tcattttcgt ttagataaag tgactgtttc
     4921 tttaaatatt taagatataa taaggctttc aaaaatttaa aacttaaaat aataactaaa
     4981 actatccaaa taactgtgca gatattatca attgaatccc aattaaactt atggatatct
     5041 gttgcgaact cttgaacagg tttggtggta attatgttat ggttcaagtc gtgtgactta
     5101 ctttcaactg tgggcgcttg attattcaca ttattaaatt ttataaaaga gaatttaatt
     5161 gggataaaag gaattaatcc agcaagcaca gttagatacc aaactttata atttaaacta
     5221 taattaaaat agcgttttaa tatgtaccta aaaaatacta acaatagaaa tataaaacaa
     5281 aagcttacta cactcattat tagtaattta gccattttga caccttcttt caaatattta
     5341 taataaacaa ttgacatcaa tattacaatt gtaatattat tgttttgtaa aaattacaac
     5401 tgtaatatcg gagggtttat tttgaaaaag ttaatatttt taattgtaat ggctttagtt
     5461 ttaagtgcat gtaattcaaa cagttcacat gccaaagagt taaatgattt agaaaaaaaa
     5521 tataatgctc atattggtgt ttatgcttta gatactaaaa gtggtaagga agtaaaattt
     5581 aattcagata agagatttgc ctatgcttcg acttcaaaag cgataaatag tgctattttg
     5641 ttagaacaag taccttataa taagttaaat aaaaaagtac atattaacaa agatgatata
     5701 gttgcttatt ctcctatttt agaaaaatat gtaggaaaag acatcacttt aaaagaactt
     5761 attgaggctt caatgacata tagtgataat acagcaaaca ataaaattat aaaagaaatc
     5821 ggtggaatca aaaaagttaa acaacgtcta aaagaactag gagataaagt aacaaatcca
     5881 gttagatatg agatagaatt aaattactat tcgccaaaga gcaaaaaaga tacttcaacg
     5941 cctgctgctt tcggcaagac tttaaataaa cttatcgcaa atggaaaatt aagcaaaaaa
     6001 aataaaaatt tcttacttga tttaatgttt aataataaaa acggagacac tttaattaaa
     6061 gatggtgttc caaaagacta taaggttgct gataaaagtg gtcaagcaat aacatatgct
     6121 tctagaaatg atgttgcttt tgtttatcct aagggccaat ctgaacctat tgttttagtc
     6181 atttttacga ataaagacaa taaaagtgat aagccaaatg ataagttgat aagtgaaacc
     6241 gccaagagtg taatgaagga attttaatat tctaaatgca taataaatac tgataacatc
     6301 ttatagtttg tattatattt tctattatcg ttgacatgta taattttgat atcaaaacct
     6361 gattttccct ttattatttt cgagatttat tttcttaatt ctctttaaca aactagaaat
     6421 attgtatata caaaaaatca taaataatag atgaatagtt taattatagg tgttcatcaa
     6481 tcgaaaaagc aacgtatctt atttaaagtg cgttgctttt ttctcattta taaggttaaa
     6541 taattctcat atatcaagca aagtgacata attgttgaat ttatagtaac tgaaacgtat
     6601 gattagggtg tatattaatt atgagatgga aatcaatgat tgttggctat gcgagagtat
     6661 catcgaacga tcaaaattta gaaagacaac ttgaaaattt aaagacgttt tgtgctgaaa
     6721 aaatatttac agaaaaacag tctgggaaat ctattgaaaa tagaccagta cttcaagaag
     6781 cacttaactt tttgaggatg ggagatcggt ttgtagtaga atccattgat tgtttaggtc
     6841 gtaattatga tgaagtgatt cataccgtta attatttaaa agacaaagaa gtacaattaa
     6901 tgattactag cttacctatg atgaatgaag tggttggcaa tccattactg gataagttta
     6961 tgaaagattt aattattcaa atattagcaa tggtttcaga acaagagaga aatgaaagta
     7021 aacgtcgaca agcgcaagga attcaagttg cgaaggaaaa aggcgtatat aaagggcgcc
     7081 ccttacttta ttcaccaaat gctaaagatc cacagaaacg tattatttat catcgcgttg
     7141 tagaaatgtt agaagaaggc caatcaatta gtaaaattgc gaaagaagta aatataacaa
     7201 ggcagacgat ttacagaatt aaaaacgata atgatttgat ttaataaact ttgtttcaat
     7261 gcaactgaga gcttctcaca gcgtctcaaa acagatgatt ataatctatt atgagttttt
     7321 aataataaga caagaaaaga gagcgtaaat atgctctctc tttttctcat taacgaatgt
     7381 ttataacgca atcatgatga gagtattaat acagttaatt atttgaaata ctttagttta
     7441 tataatgttg aattataggt agtgaaattg tatttattat acattgtcat atcgttgttt
     7501 aatgatagtt aatttaagga taatagaatt aatattatat atagatgaac aaaacaagca
     7561 acagagcaga aaaaacactt ttagattatt tttactcatt ctctatttta tttatttttg
     7621 ctataataaa taaagaatat taaatggagg tgtttttata aaaaagaaat ttgtttctag
     7681 ttgtattgct agtacaatct tattcggcac tttattaggt gtaacttata aagctgaagc
     7741 tgcaacagta catgtagctg gtggtgtttg gagccatggt attggaaaac attacgtatg
     7801 gtcttattat agtcacaata aaagaaatca tggttcaaca gcagtaggga aatattcatc
     7861 ttttagtggt gttgctcgac ctggtgttca atctaaggca tctgctccaa aggcttgggg
     7921 tggaaacaaa acattttata gtcttcacta attacatata ttaattaagg agaatagaca
     7981 gaattaagta aacttaattc tgtctattct cttgaaagag gcaatatgaa aaaattcaaa
     8041 ttatttttag attttagtac tttattatta atttcagggc tattattttt atttttcttc
     8101 aaagaaaatg aagaaattat acctgaaagt tccaatattt taacaatctc taattgggat
     8161 aaatctaaca gtaaatcaaa agtgttagat gtcattgaat caggcgccaa aaatcaaaat
     8221 atacaaataa ttaaatccgt taaagatttt gataataaaa aagaattttt tgttttcaac
     8281 tcaaaacgaa ataattctga ctttatacgt aataaaacat cacttttaac tccatcagat
     8341 ttattaaaca gagagataaa aggaaagtat tatattattg gtgaacattt caatgtagaa
     8401 gagcttacga gtgaattaaa aaaagctggt ttaacatctg aagttgaata cataaataga
     8461 aacatattat tttttgaatt agtcatagat aatgatttat tagtgccttt catattctta
     8521 ggcgtattat atcttttgta cttcttatat gacagaggat ataatttgaa attttatgct
     8581 attcaaaagc tacatggctt ttcaactaca cgcattattt ttcataatat tcatataaaa
     8641 atcatttatt ggctagtact taccgctatt ttctttattg ctaatatatt aatcattcat
     8701 atagccaatt tagaattgga tttcttaatg tttattcgta gatttatcgt gttgcttttt
     8761 gtttttgctt gtattactac attgctgtgg ctgatttcgt atagtcttct tttgaagtta
     8821 agtattccat taatcttaaa agggaaaaaa ggatataagt tttcaatatt tatgggtacc
     8881 ttcaccaaat gtatcatggt gctaatacta tcttttttac tggcacaaaa tttaaatgct
     8941 tatacgaagt taaagaatat atatgactct gaaaaaatct ggcaaaagtt agataattac
     9001 tatacattag agatttctcc taatattaga aattcagaag aaaaacaaat tttagaaact
     9061 aatatataca atttaattaa gaaaagcgaa caacttggtg gattgctttt aaagaataat
     9121 aatatagcca atcccgataa aaacaattac attcctgaaa atggcaatgt cttttttatc
     9181 aataacaatt ttctgaattt ctataaaaat ataaatcatg attttaaaat gattgacaat
     9241 cattcggata aaataaacgt gtttattcct ccaaggttac aatatcaaaa atctgaaatt
     9301 caaaaaaatc accaaggatg gattgacttt caaaagcaac aaaacaaaaa agtagatgtg
     9361 caagtactgt caaaaaacgt atctgttttt tcttttgatc gcacaactaa tttgaaattt
     9421 gggtatctag attctccaat agtaatgttg ttgacacttg acgatttaac aggagatttt
     9481 tatttagctg ctgtttctca aggtggatat ctatttaaag atttagatac acttaaacag
     9541 ttgcttaaag ataatcacct agaagaagaa attagcggta taactaatta caaggattct
     9601 gtgttaaatg aattaaatga aacgaaaaca aaaatgataa taacaatagt tactattatt
     9661 attaacgttt tcattctttt gatagctact gtatttgaaa caattcaata ttttagctgg
     9721 aataaaaagc aactattatt aagaaaaatt catggttatt cattattcag cagtaatgta
     9781 cgttatttaa caatttctat cttactttct attatgttag cttacactac gcatatttta
     9841 tttggttcaa agatattact attcataata atgtctattg ctattattca acatttactt
     9901 caaattgctt atattaaata tcttgaaaaa tactttaaag atttaatgag ggagatttaa
     9961 acaatgaaaa gaactttaat tattgtaaca attgtactat taatcatcat acttagtctg
    10021 ttattggtta gaaatgagca tttagatcgt tttaacccac tgttaaaaga aaaagtatct
    10081 tatgccaaag ttccaaaaga tacccaggac tatagaaata taactgtata ctctaaaaat
    10141 ggagaaaaaa agagttataa attggatttt ttaggttatg atcctacaaa agaatatgtg
    10201 aaagtaaatc ataaagggaa atatgtgcgt tcgatagaat acattacaaa agatattcct
    10261 agctttttaa aatgaggtga ccgatagtga taaaacttga aaatgttttt gtaaaaaaag
    10321 gtaataaaaa cattttagac ggatgtaact ttaattttga aaaaggaaaa tcatatgctt
    10381 tagttggaga aagtggcgct ggaaaatcta ctttacttaa cataatcgct gggttcgaag
    10441 atgtatcaca aggaagcata tatattgaag ataagttact aaaaaagaaa gtcgattttt
    10501 atagatatac gttagggtat ttgtttcaaa attttgcttt acttgaaaat caaacaatca
    10561 gtcaaaattt agatttagcc ctaaagttca aaaagaataa aaaagataat atgaacttaa
    10621 agaaagaagt attaaaaaag gtcggcctag atttagatat caagagaatt gttagttctc
    10681 taagcggtgg tgaacaacaa agagtagcat tggcaagatt aatattaaaa gatccgaaaa
    10741 tcattttagc tgatgaacct actgggtcac tagatacgaa aaatggaaaa atagttattg
    10801 atttattatt gaagctactt gatgaaaata aaactatgat tgtcgtaacg catgatttag
    10861 agcttgcgaa acgatttgat gtcatagtca atatttctga gcttagaagt taagaaatat
    10921 tgataggtat agccatacat agagaaaaaa caatatgaaa tatgattagt cattactttt
    10981 gagtttttta atttaaggac tggattttcc agtccttttt tatgatgaca aaaaacaagc
    11041 ctcgcagagc acacgttttt aatgacttat ttggttttta ataagtctag tatgttaaaa
    11101 cttttctgtg tttaggtgtt ataatcatat gcagtggaag ttgatttatt atgtcttatt
    11161 caattattcg agttgttaaa gtgaaatcaa aaacaaatac aagaggtatt caaagacata
    11221 ttcaaagaga aaataaaaat tatgaaaata tagatattga tttaagtaag tcatatttaa
    11281 actatgattt agtcaatgat actaagtttg attttaataa aaaaattgat gagaaaatcg
    11341 aaaaaaatta taaagggaaa cgcaaaatta gaacagatgc cattaaacat attgatggat
    11401 taattacatc agataatgtg ttttttaatc aattatctga agaagagaca aaatagtttt
    11461 ttaagcatgc taaagcgttc ttggaagaag aatacggtaa agaaaatctt ttatatgcga
    11521 cagtacatat ggatgagata acaccacata tgcattatgg cgtagttcct attactaaag
    11581 atggacgttt aagtgcgaaa gaagttgtag gtaataaaaa agcattaacc gaattccaag
    11641 atagattcaa tacgtatatt aataagcaag gctatgattt aaaacgagga atttctagac
    11701 aacttacaaa agaaaaacat gatcaagtta gccgttataa acaaaaaaca gaatatcata
    11761 aacaaatgca tatgcgctag aagcaaatag aggattattt aaagcaagaa aatgataaat
    11821 tgatacaaaa ctaccaaaaa tcattagata cgcttaaaaa gcttctgagt gtcatgtatg
    11881 aaattaaaac taaaaatgta ggtggatggt ttcataaaga gaagcaagaa acaggcaata
    11941 ttgtaattac taaaactgat tttgaaaaat acactaaaca aattaaagca gcacagatga
    12001 tattagatga ttatgaatgt attaaaagtg ggaagtcatt aaaaaaagca gagaaacaaa
    12061 atgaaagttt agttaatgaa ttgactagtg tccatatgga aaatgaaaag ctggttgaag
    12121 aatttaatga tttagcacaa cgttataatt atttgttgtc agagaatgaa aagaaagata
    12181 aagaactaaa ttatacgctt aagttattca atcaagtttt taaaatcatt aaaagtatga
    12241 tgaaagaaga gcgttatcat acactaataa atcatattga taatcattta gacaattcta
    12301 aaatacgtga agtaatgacg atagataaca atgatgaaca gttctttaag aagaaatatc
    12361 aagcacaaga acgagaaatc atttttaaag aagatagaga agatggttat acattataaa
    12421 aatagatatt taaatgcatt tgtttgaggt taattatttt ttaggatgaa aaataggtag
    12481 cccccctcga actttttaat atatttttat aaatcttttt aaaaaccttt ttaggggctt
    12541 gttcagccct agagcaacaa gggatttcaa tgcctaaagg agtgtttttg ccacataaaa
    12601 ggagtgtttt tgccacataa aaggagtgtt tttgccacat aaaaggagtg tttttgccac
    12661 ataaaaggag tgttttaaaa agttgtactc cttttatggt ttgacattga taataaagta
    12721 gtttattgtg aataaaagtt ttcaaatggg agtgtatatt caaacgatac tcctttaggt
    12781 tcgtaataaa gggggctgta tcatgacagg agagacagtt gtatataaaa atgaaatgaa
    12841 tttagttcca ttaaggcgat ttacagctac tgaaattaat ttattttttg cgatgtgtaa
    12901 taaattaaaa gagcaagata ctaatacatt acgtttgtct tttgatgaat taaaaaaatt
    12961 aagtaattat agtccagaaa cacgtaatat taatagattt gctaatgatt tagataatgt
    13021 gtataaaaag atgttgaatt taaccattag atatgaagat gatgatgtaa tagaaagatt
    13081 cgttttattc aatcattata gaatccataa gcgagaacaa tatctagaaa tatcaacttc
    13141 ttcaaattta aaacacatat tgaattcaat tactaataat tttacaaaat ttgaattaaa
    13201 agaaatgact aggcttaaat ctacatattc taaaaatatg tttagattac ttaaacaata
    13261 caaacataca ggctatttaa aaattcacat cgatgatttt aaaaatcgtt tagatatacc
    13321 taaatcttat cgtatgactg atattaacaa aaatattttt aaacctatta ttattgaatt
    13381 aggttctata tttaataatc ttactatcaa taaaatcaaa gcgaaaaaag ggcgtaaaat
    13441 tgaatggata gagttcacat ttgacgctga gaaacgcatt cataacaaac gacaacctca
    13501 aatgtccaag atagataaat caagacaata tgtgaggcgt gaaaagacgc ctaaatggtt
    13561 agaagaacgg tcatatgaaa agcaacctca aaaagattac gacccacaat tagagaaaga
    13621 acgagaggat tttttaaaac aacttgaact gaattgggaa taacgcaact tttcgttgcg
    13681 agttggttaa ctaaaagtat cgtgactttt caattatttt aattatagtt tgagttaagg
    13741 agtgatttta tgaaattagc tgaagctata aaagaacaga gagaattaaa aggatggtct
    13801 caagaggaat tagccaatat attaaaggtt tccagacaaa gtgtttctaa atgggaaagt
    13861 gccaaaaact atccttcctt agatattttg attgctatga gcgatttatt cggaatctct
    13921 ttagagcatt taattaaagg agatgcacgt tttaaaaaag ttattttaga gggaaattat
    13981 agagagagta acagggtacc ttccatagtt gattttcttt atgatttttg gtggcttttc
    14041 tttcctgttg ccggattttt agtttgggcc attcattcgt tcatgggttg attttaaaat
    14101 caaaatttaa tgcacatcag gcaatatgaa aaaggaaagt atttttacga caccttgaaa
    14161 tgtattgata agaatagaag agtttacaaa aggcaatatg aaatatatac taaaagtaac
    14221 aagaatttcg tttgtaaacg cacaaaaccc cgaactattc gccgtagttc ggggtttttt
    14281 ggtgaattgg ctttaatcgt ctatattatt ttttatcacg tttatggagc taataaccaa
    14341 ataacgtaac gagacaacca ctgattgccg ttgtcatgat gtgaacaaga atttcattca
    14401 taaatcgcac ctcctctcta cgccgaattg acatctgaga gatagacgac cttcacatta
    14461 taacaaatct ctccttccat gaaataacat gaatattaat aaatgttgtt atatattaaa
    14521 gataaataaa tataagggtg ggattgataa tgtttggcga tcaaagacaa gaagctacaa
    14581 aatatgtcat taaagaaggt tatcaagata tttatttcct caacaaaaac ggggaatggt
    14641 attatttcga agtaagaagt gtctggcgtg gcaaacatat tattagagtt aaagatggtt
    14701 tgttaggttg gagaaaagaa atagtaactg aataaagata caaaatactt gccaatgcaa
    14761 aagaatgaaa acgcgtcaaa tcaacgatgt ataaaagatg cataaaagat aatgaaagta
    14821 aaaagccata aatgccgtca tataggcatt tatggctttt tgtttggtta acataatcga
    14881 tgattatcag aagttcaatt cacataaaaa agcacggcta atttatgaac ttgtcgtacc
    14941 tttttaatta aaattagtta ccaaatagac gactccaaaa ccccttttta ggttccgttt
    15001 cttcactctt ttcttctata tcactatcat tgtcatttgg attagctgaa acgtcttctc
    15061 tttgtgcttc ttcaccttgt gtactttcgt cgctttgact tccagatata tccttatatt
    15121 gaatctctgt ttctttagtt tcttcctgat ctcggttaat atttacagga ctagtagtat
    15181 atgttttttc ttgtgcatca acgttttgtc tagcgttagt agatgtatca aagggataat
    15241 taaggtgttt ttctttttct aattgatttt ctaatttttg aatcttttta ttactctcta
    15301 atgccagaac ttgctgattc tcaagcaatt ttgatctttc ttgcaactct tttctgtaaa
    15361 attcaattgt tgtttcatga cgactttctt gtttttcaat ttgattattt aaagtattaa
    15421 tctgattttt aagtatttct actatttgag catcgctttt agattcaaaa ttaatattat
    15481 ccgactcttt tttttgtttg tcttcagtag cactttcaaa accatatttc tttttatttt
    15541 catttactct ttgaatgatt ttttctatat cggtatcttc tttaataaac gaagtgtttt
    15601 cctgttttat tgtctctata ttcaatctct taatattatt aaaaatcgtt tgcttactaa
    15661 cccctaattc ttcactcaac ctttttacac ttttcatatc atcaaccctt tataaaatgt
    15721 ttataaaccc ttagtaaaat attataagct tataacgatt aataataaag taatcgacaa
    15781 ataaaaatat aaattcgcca acctttttat caagggtttg taaagggttt atggtgttta
    15841 tcaaaggttt ataaacctat attttccctt ttttaagttt attcaaagtg ctataataac
    15901 cttaatataa caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta
    15961 gaaactgttt atttatataa ttttcgatac ttagattata taatgaataa tatcttagtg
    16021 caagcaccta gattattaaa taaacacaaa aaatgtaagc gttttattac ctcttaccaa
    16081 actaaaattc ggaaagaggt ttttattatg tcaattaaac tttacaacat aaatgaggaa
    16141 tacagagaaa agttttatca aataccgaaa gtatttttta caaatcctaa atatatcaag
    16201 ttatccaatg atgcaaaaat ggcatggggt attcttagag atcgtttaga tttatcaatt
    16261 aaaaatggtt gggttgattc taaaacaggt aatatttatt tttattacaa aaatgaaaac
    16321 ccacaaaata tattaaattg taaaaaagat aaagtaatta aaataaagaa agaacttaat
    16381 tgaagccgaa ttactactac aagaaagaca aggtttaaat aagacaaata aactttattt
    16441 agttaaacca gaagtaacag aagatgatat ttataaaatt caaaagcaag aaaacactgt
    16501 tgagagcagc aatggcaagg aagtcggaaa aaccgacttc aagaagtcga taaaacagaa
    16561 tctaatgata ctgaacttag ctatactgaa tctaacaata ctgaaataaa tgatatgaat
    16621 gacttgaatg atatagagtc cgaaaatgaa attagtaatc attcaagtca atgcaaggtt
    16681 atttaatgca aacaatttta actgaatttg aagaaacaca tgcactttat atgcgccgta
    16741 aaaacatgaa acaatataat atctttaatc aatcattcaa atgattttat aacaatcaaa
    16801 gatacatcaa aatatttcgt taaatcatct gactttttaa ctgatagcga tgaaaaaatc
    16861 aagaaattgt cagtgatcta gaaaaagatt tgtatcgaaa acgtatgtta agttatggtg
    16921 gattgcttaa ataaaaacat aaaattttaa acttagacga tgctgaagat ggcaatttaa
    16981 ttaatacaag tgatgaagat aaaatagcaa atgaagaaga aaaggcacat tcgattacgg
    17041 caattttgaa aagcaaaatt attatttaag gcattagtga taactgatgt ctttttttat
    17101 tacttttttg taaaaaaagt gctgtcttat ttttgtgaca aatgctgtat gtagtgtcac
    17161 aaaagtgtga cacttgagct ttttatgacc ccacacaaaa acattttcga agccttgaaa
    17221 tatctggctt tgccagatcc cccattcatt gatggggaca aatttccctt atgctcttac
    17281 ggagatttta gagttaaatt aaaatttcta agtttttgat aagaaaagcc ctgcaggaat
    17341 ttagaagaac gtggggaagt tttaaagaat tttatgctaa tttttaattt gcatgtaaat
    17401 gggcagtgtc taaaaaatag ttattgtttt tgctcaaatt tttgtttttg aaaatagcat
    17461 atatttattt ggctcatatt tgcgttttaa aagcgtatat aagttttaga tataaaacta
    17521 tatgaatcac ccctaaatct ttaaaatgcc ctcttaaaat tcaaaataag ggcataaaaa
    17581 ataaaagccc ccccagataa agtgaggtag ctttttcttt cgacgccgta tcgtcgatgt
    17641 aattcaaaaa agttatgggc tataaatcta catcactttt tcaagaatgt agtagcaata
    17701 ttcaacgcaa attaattttt ataactgctc ggaatatctc aagccgtttc tttaattttg
    17761 aaataaaaaa atcgacgaag gtcgattacg tttttgcaca tgtcgattta tccgacgtat
    17821 aagtgcgccc ttacgggatt taactagatt ataacgacga attttagacc tgtaaagcaa
    17881 taacaattag gtctaccagg tagataaagt gtacaaagta gaaccgaaaa agttatttat
    17941 tttgaagatt tttcgtagat ataatttgct aataaacttc ctaaaactga ataaagaaaa
    18001 atagttaaac tcatgtaatc actccataat tctgaagtgt ctccatgtct acgcatagac
    18061 acgcatttat gccgagaaaa tttattgtgc gttgagaaga acccttaact aaacttgcag
    18121 acgaatgtcg gcatagcgtg agctattaag ccgaccattc gacaagtttt gggattgtta
    18181 agggttccga ggctcaacgt caataaagca attggaataa agcacctatg attatttaaa
    18241 aatataagtt ataatacatt caaaaatatt tttgaatgag gtgtattatg attcaaacgg
    18301 ttgttgctgc tgctgttctt tatattgcta cagcagttga tttattagta attttattaa
    18361 tattttttgc tagagcaaag actagaaaag aatatagaaa tatttatgtt ggtcaatatt
    18421 tagggtctat tattttaata ttagttagtt tgtttttagc ttttgtatta aattatgttc
    18481 cagaaaagtg gatattaggt ttattgggtt taataccaat ttatcttgga attaaagtgg
    18541 ctatttatga tgattgtgaa ggagaaaaga gagctaaaaa agaattgaat gaaaaaggat
    18601 tgtctaaatt agttggtacg gttgcaattg ttacgatagc aagttgtggc gccgataata
    18661 ttggtttatt tgttccgtat tttgtgacat taagtgttac taatttatta cttactctgt
    18721 ttgtcttttt aattttaatt ttcttcttgg tgtttactgc acaaaaatta gctaatatcc
    18781 caggaattgg agaaattgtt gagaaattta gtcgttggat tatggctatc atttatatag
    18841 ctttaggttt atttattatt attgaaaatg acactattca aacaatttta ggatttatat
    18901 tttaatttag ggtgtgattt tatatgagtt atgaaaatac ttgtgatgtg atctgtgtac
    18961 atgaggataa agttaacaat gctttaagtt ttttagaaga tgataaatct aagaaattac
    19021 ttaacatttt agaaaaaatt tgtgatgaga agaaattgaa aatcatatta tctttgatta
    19081 aagaagatga gttgtgtgtt tgtgatattt ctttgatatt gaaaatgagt gttgcttcaa
    19141 cttcacatca tttaaggctt ttatataaaa atgaggtact tgatttttat aaagatggaa
    19201 agatggcata ttattttatt aaagacgatg aaataagaga gtttttctct aaaaatcagg
    19261 agggtttttg aaacgagtga aacgagtttc ttcttgtctt gatactataa aaaacaaagt
    19321 tatataacat aagacgactt atcggaagtt atctatcatc gtatattcgg agatgatata
    19381 atatacaggt cgcctatctc tcaggcgtca attcagacgc agagaggagg tgcattactt
    19441 tgctaatcat tttcgttcac atcatagcac cagtcatcag tggctgtgct gttgcgtatt
    19501 atacttattg gcttagtaaa cgcaacaaat aattaatagg cgactttata agccagcatc
    19561 gaaaaaatcc ccacactatt gcagtagtgt ggggattggt gcattaattg ttaatcattt
    19621 tcgttatcta gattataaca ctggttagta gaggaatgca aaaagataat attttaagta
    19681 gtctttttgg atattatcat atgatatatt tatgtaaatt gattttttat taaaggagca
    19741 tatatgagta atactaaaat taaatatcaa atttttattt catcaactta tttagattta
    19801 atagaagagc gtcaagcagt agtagaagca gttttaaaca gtaataatat tccagcaggt
    19861 atggaacttt ttaactcaag tagtaaaagc caatgggaaa taataacaca atggatcaat
    19921 gaatcagatg cagtgatatt attgttaggt tctagttatg gaacaattga tagtgaagaa
    19981 aatattagct atacagaaat ggagtacaat tttgctaaat ctttaggtaa acctatatat
    20041 gtttttgaga tgaataaagc atctaccgaa tccgcggaaa agtctaaaaa attagatgag
    20101 tttaagacaa aagttaaaga aaatagacta attagtccaa atattaatga tatttcggaa
    20161 ttaaaaagta aagtatctca gactttaatg caaagtgtac ctagtgaaat taaagaaaat
    20221 agtggatgga taagagtaca ggattgtggt aaaaatgtaa aaaaattaaa aaaattggat
    20281 gctatacaaa gagatttaga tacatatgat tttttgaaag aagaacttta taaaatattc
    20341 atgtatgtaa aaacttttta tttccagcac acaccatttg atgatagtta tattgaagat
    20401 atagaaaact acctgctaaa ttatgaaaat aatccacata aatcattcat gaaaataaaa
    20461 gtttatgatt ataaaaactt tttaaaacat ttaaaaaaca tattgatttt aattaaacaa
    20521 ggaaaaaagc cattagctca agccggtcat tttaaattaa gcttttacga agaggattta
    20581 aaattgttac aaaaaaatta taagactacg ctagtcgata ttaaaggatt gaataaacat
    20641 ttttataagg aatgtgatag gtgcttaaaa gcatataata tttttattga gggtataaat
    20701 aaacatttat atgaatgata taagtacacc
//
