LOCUS       NZ_CP120024            20729 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Staphylococcus aureus strain Dog147 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP120024
VERSION     NZ_CP120024.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33696829
            Assembly: GCF_034043095.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20729)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Canine Staphylococcaceae circulating in a Kenyan animal shelter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20729)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
  REMARK    Annotation added by database at the submitter's request
REFERENCE   3  (bases 1 to 20729)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Flye v. v2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 488x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/06/2024 10:57:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,734
            CDSs (total)                      :: 2,651
            Genes (coding)                    :: 2,584
            CDSs (with protein)               :: 2,584
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 33 of 67
            Pseudo Genes (incomplete)         :: 33 of 67
            Pseudo Genes (internal stop)      :: 20 of 67
            Pseudo Genes (multiple problems)  :: 18 of 67
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20729
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Dog147"
                     /isolation_source="nasal swab"
                     /host="Canis lupus familiaris"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya:Nairobi"
                     /lat_lon="1.3345 S 36.7331 E"
                     /collection_date="2015-06-27"
                     /collected_by="Joerg Jores, Anna Lacasta, Anne Liljander,
                     Paul Ssajjakambwe (International Livestock Research
                     Institute, ILRI)"
     gene            complement(397..>679)
                     /locus_tag="P3U63_RS13550"
                     /old_locus_tag="P3U63_13550"
                     /pseudo=""
     CDS             complement(397..>679)
                     /locus_tag="P3U63_RS13550"
                     /old_locus_tag="P3U63_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(690..1366)
                     /locus_tag="P3U63_RS13555"
                     /old_locus_tag="P3U63_13555"
                     /pseudo=""
     CDS             complement(690..1366)
                     /locus_tag="P3U63_RS13555"
                     /old_locus_tag="P3U63_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            1777..2520
                     /locus_tag="P3U63_RS13560"
                     /old_locus_tag="P3U63_13560"
     CDS             1777..2520
                     /locus_tag="P3U63_RS13560"
                     /old_locus_tag="P3U63_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(2739..2924)
                     /locus_tag="P3U63_RS13565"
                     /old_locus_tag="P3U63_13565"
     CDS             complement(2739..2924)
                     /locus_tag="P3U63_RS13565"
                     /old_locus_tag="P3U63_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            3073..3144
                     /locus_tag="P3U63_RS13570"
                     /old_locus_tag="P3U63_13570"
     CDS             3073..3144
                     /locus_tag="P3U63_RS13570"
                     /old_locus_tag="P3U63_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(3383..3724)
                     /locus_tag="P3U63_RS13575"
                     /old_locus_tag="P3U63_13575"
     CDS             complement(3383..3724)
                     /locus_tag="P3U63_RS13575"
                     /old_locus_tag="P3U63_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(3811..4671)
                     /locus_tag="P3U63_RS13580"
                     /old_locus_tag="P3U63_13580"
     CDS             complement(3811..4671)
                     /locus_tag="P3U63_RS13580"
                     /old_locus_tag="P3U63_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            4729..5013
                     /locus_tag="P3U63_RS13585"
                     /old_locus_tag="P3U63_13585"
     CDS             4729..5013
                     /locus_tag="P3U63_RS13585"
                     /old_locus_tag="P3U63_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            complement(5055..5600)
                     /locus_tag="P3U63_RS13590"
                     /old_locus_tag="P3U63_13590"
     CDS             complement(5055..5600)
                     /locus_tag="P3U63_RS13590"
                     /old_locus_tag="P3U63_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(5694..6323)
                     /gene="mobV"
                     /locus_tag="P3U63_RS13595"
                     /old_locus_tag="P3U63_13595"
                     /pseudo=""
     CDS             complement(5694..6323)
                     /gene="mobV"
                     /locus_tag="P3U63_RS13595"
                     /old_locus_tag="P3U63_13595"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(6561..7187)
                     /locus_tag="P3U63_RS13600"
                     /old_locus_tag="P3U63_13600"
     CDS             complement(6561..7187)
                     /locus_tag="P3U63_RS13600"
                     /old_locus_tag="P3U63_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(7199..7510)
                     /locus_tag="P3U63_RS13605"
                     /old_locus_tag="P3U63_13605"
     CDS             complement(7199..7510)
                     /locus_tag="P3U63_RS13605"
                     /old_locus_tag="P3U63_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(7514..9448)
                     /locus_tag="P3U63_RS13610"
                     /old_locus_tag="P3U63_13610"
     CDS             complement(7514..9448)
                     /locus_tag="P3U63_RS13610"
                     /old_locus_tag="P3U63_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(9523..9816)
                     /locus_tag="P3U63_RS13615"
                     /old_locus_tag="P3U63_13615"
     CDS             complement(9523..9816)
                     /locus_tag="P3U63_RS13615"
                     /old_locus_tag="P3U63_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(10230..10838)
                     /locus_tag="P3U63_RS13620"
                     /old_locus_tag="P3U63_13620"
     CDS             complement(10230..10838)
                     /locus_tag="P3U63_RS13620"
                     /old_locus_tag="P3U63_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(11207..12052)
                     /gene="blaZ"
                     /locus_tag="P3U63_RS13625"
                     /old_locus_tag="P3U63_13625"
     ARG             complement(11211..12052)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            12159..13916
                     /gene="blaR1"
                     /locus_tag="P3U63_RS13630"
                     /old_locus_tag="P3U63_13630"
     ARG             12160..13913
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="96.07"
                     /coverage="100.0"
     gene            13906..14286
                     /gene="blaI"
                     /locus_tag="P3U63_RS13635"
                     /old_locus_tag="P3U63_13635"
     ARG             13907..14283
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            14550..15143
                     /locus_tag="P3U63_RS13640"
                     /old_locus_tag="P3U63_13640"
     CDS             14550..15143
                     /locus_tag="P3U63_RS13640"
                     /old_locus_tag="P3U63_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_054192780.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERSVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKKDEKQGEVSN"
                     /name="recombinase family protein"
     gene            15115..16557
                     /locus_tag="P3U63_RS13645"
                     /old_locus_tag="P3U63_13645"
     CDS             15115..16557
                     /locus_tag="P3U63_RS13645"
                     /old_locus_tag="P3U63_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_054192781.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISESKGI
                     ALSTLYRWNKSYKEQGLKGLIYATRADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     ITNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDLQHARSQRRKHLKQNIASPSTTELIKKEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            16550..17365
                     /locus_tag="P3U63_RS13650"
                     /old_locus_tag="P3U63_13650"
     CDS             16550..17365
                     /locus_tag="P3U63_RS13650"
                     /old_locus_tag="P3U63_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(17485..18459)
                     /locus_tag="P3U63_RS13655"
                     /old_locus_tag="P3U63_13655"
     CDS             complement(17485..18459)
                     /locus_tag="P3U63_RS13655"
                     /old_locus_tag="P3U63_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_054192782.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKNLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(18671..18763)
                     /locus_tag="P3U63_RS13660"
                     /old_locus_tag="P3U63_13660"
     CDS             complement(18671..18763)
                     /locus_tag="P3U63_RS13660"
                     /old_locus_tag="P3U63_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18932..19279)
                     /locus_tag="P3U63_RS13665"
                     /old_locus_tag="P3U63_13665"
     CDS             complement(18932..19279)
                     /locus_tag="P3U63_RS13665"
                     /old_locus_tag="P3U63_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(19298..19915)
                     /gene="cadD"
                     /locus_tag="P3U63_RS13670"
                     /old_locus_tag="P3U63_13670"
     ARG             complement(19302..19915)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     ARG             complement(11208..12052)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             4523..14816
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(193..340)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          1778..2520
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(3812..4671)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(6049..6323)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 gccaaataaa tatatgctat tttcaaaaac aaaaatttga gcaaaaacaa taactatttt
       61 ttagacactg cccatttaca tgcaaattaa aaattagcat aaaattcttt aaaacttccc
      121 cacgttcttc taaattcctg cagggctttt cttatcaaaa acttagaaat tttaatttaa
      181 ctctaaaatc tccgtaagag cataagggaa atttgtcccc atcaatgaat gggggatctg
      241 gcaaagccag atatttcaag gcttcgaaaa tgtttttgtg tggggtcata aaaagctcaa
      301 gtgtcacact tttgtgacac tacatacagc atttgtcaca aaaataagac agcacttttt
      361 ttacaaaaaa gtaataaaaa aagacatcag ttatcactaa tgccttaaat aataattttg
      421 cttttcaaaa ttgccgtaat cgaatgtgcc ttttcttctt catttgctat tttatcttca
      481 tcacttgtat taattaaatt gccatcttca gcatcgtcta agtttaaaat tttatgtttt
      541 tatttaagca atccaccata acttaacata cgttttcgat acaaatcttt ttctagatca
      601 ctgacaattt cttgattttt tcatcgctat cagttaaaaa gtcagatgat ttaacgaaat
      661 attttgatgt atctttgatt gttataaaat catttgaatg attgattaaa gatattatat
      721 tgtttcatgt ttttacggcg catataaagt gcatgtgttt cttcaaattc agttaaaatt
      781 gtttgcatta aataaccttg cattgacttg aatgattact aatttcattt tcggactcta
      841 tatcattcaa gtcattcata tcatttattt cagtattgtt agattcagta tagctaagtt
      901 cagtatcatt agattctgtt ttatcgactt cttgaagtcg gtttttccga cttccttgcc
      961 attgctgctc tcaacagtgt tttcttgctt ttgaatttta taaatatcat cttctgttac
     1021 ttctggttta actaaataaa gtttatttgt cttatttaaa ccttgtcttt cttgtagtag
     1081 taattcggct tcaattaagt tctttcttta ttttaattac tttatctttt ttacaattta
     1141 atacattttg tgggttttca tttttgtaat aaaaataaat attacctgtt ttagaatcaa
     1201 cccaaccatt tttaattgat aaatctaaac gatctctaag aataccccat gccatttttg
     1261 catcattgga taacttgata tatttaggat ttgtaaaaaa tactttcggt atttgataaa
     1321 acttttctct gtattcctca tttatgttgt aaagtttaat tgacataata aaaacctctt
     1381 tccgaatttt agtttggtaa gaggtaataa aacgcttaca ttttttgtgt ttatttaata
     1441 atctaggtgc ttgcactaag atattattca ttatataatc taagtatcga aaattatata
     1501 aataaacagt ttctaaacgt tttattacca aaccccgact attaccagta gttggggttt
     1561 ttgttatatt aaggttatta tagcactttg aataaactta aaaaagggaa aatataggtt
     1621 tataaacctt tgataaacac cataaaccct ttacaaaccc ttgataaaaa ggttggcgaa
     1681 tttatatttt tatttgtcga ttactttatt attaatcgtt ataagcttat aatattttac
     1741 taagggttta taaacatttt ataaagggtt gatgatatga aaagtgtaaa aaggttgagt
     1801 gaagaattag gggttagtaa gcaaacgatt tttaataata ttaagagatt gaatatagag
     1861 acaataaaac aggaaaacac ttcgtttatt aaagaagata ccgatataga aaaaatcatt
     1921 caaagagtaa atgaaaataa aaagaaatat ggttttgaaa gtgctactga agacaaacaa
     1981 aaaaaagagt cggataatat taattttgaa tctaaaagcg atgctcaaat agtagaaata
     2041 cttaaaaatc agattaatac tttaaataat caaattgaaa aacaagaaag tcgtcatgaa
     2101 acaacaattg aattttacag aaaagagttg caagaaagat caaaattgct tgagaatcag
     2161 caagttctgg cattagagag taataaaaag attcaaaaat tagaaaatca attagaaaaa
     2221 gaaaaacacc ttaattatcc ctttgataca tctactaacg ctagacaaaa cgttgatgca
     2281 caagaaaaaa catatactac tagtcctgta aatattaacc gagatcagga agaaactaaa
     2341 gaaacagaga ttcaatataa ggatatatct ggaagtcaaa gcgacgaaag tacacaaggt
     2401 gaagaagcac aaagagaaga cgtttcagct aatccaaatg acaatgatag tgatatagaa
     2461 gaaaagagtg aagaaacgga acctaaaaag gggttttgga gtcgtctatt tggtaactaa
     2521 ttttaattaa aaaggtacga caagttcata aattagccgt gcttttttat gtgaattgaa
     2581 cttctgataa tcatcgatta tgttaaccaa acaaaaagcc ataaatgcct atatgacggc
     2641 atttatggct ttttactttc attatctttt atgcatcttt tatacatcgt tgatttgacg
     2701 cgttttcatt cttttgcatt ggcaagtatt ttgtatcttt attcagttac tatttctttt
     2761 ctccaaccta acaaaccatc tttaactcta ataatatgtt tgccacgcca gacacttctt
     2821 acttcgaaat aataccattc cccgtttttg ttgaggaaat aaatatcttg ataaccttct
     2881 ttaatgacat attttgtagc ttcttgtctt tgatcgccaa acattatcaa tcccaccctt
     2941 atatttattt atctttaata tataacaaca tttattaata ttcatgttat ttcatggaag
     3001 gagagatttg ttataatgtg aaggtcgtct atctctcaga tgtcaattcg gcgtaaagag
     3061 gaggtgcgat ttatgaatga aattcttgtt cacatcatga caacggcaat cagtggttgt
     3121 ctcgttacgt tatttggtta ttagctccat aaacgtgata aaaaataata tagacgatta
     3181 aagccaattc accaaaaaac cccgaactac ggcgaatagt tcggggtttt gtgcgtttac
     3241 aaacgaaatt cttgttactt ttagtatata tttcatattg ccttttgtaa actcttctat
     3301 tcttatcaat acatttcaag gtgtcgtaaa aatactttcc tttttcatat tgcctgatgt
     3361 gcattaaatt ttgattttaa aatcaaccca tgaacgaatg aatggcccaa actaaaaatc
     3421 cggcaacagg aaagaaaagc caccaaaaat cataaagaaa atcaactatg gaaggtaccc
     3481 tgttactctc tctataattt ccctctaaaa taactttttt aaaacgtgca tctcctttaa
     3541 ttaaatgctc taaagagatt ccgaataaat cgctcatagc aatcaaaata tctaaggaag
     3601 gatagttttt ggcactttcc catttagaaa cactttgtct ggaaaccttt aatatattgg
     3661 ctaattcctc ttgagaccat ccttttaatt ctctctgttc ttttatagct tcagctaatt
     3721 tcataaaatc actccttaac tcaaactata attaaaataa ttgaaaagtc acgatacttt
     3781 tagttaacca actcgcaacg aaaagttgcg ttattcccaa ttcagttcaa gttgttttaa
     3841 aaaatcctct cgttctttct ctaattgtgg gtcgtaatct ttttgaggtt gcttttcata
     3901 tgaccgttct tctaaccatt taggcgtctt ttcacgcctc acatattgtc ttgatttatc
     3961 tatcttggac atttgaggtt gtcgtttgtt atgaatgcgt ttctcagcgt caaatgtgaa
     4021 ctctatccat tcaattttac gccctttttt cgctttgatt ttattgatag taagattatt
     4081 aaatatagaa cctaattcaa taataatagg tttaaaaaca tttttgttaa tatcagtcat
     4141 acgataagat ttaggtatat ctaaacgatt tttaaaatca tcgatgtgaa tttttaaata
     4201 gcctgtatgt ttgtattgtt taagtaatct aaacatattt ttagaatatg tagatttaag
     4261 cctagtcatt tcttttaatt caaattttgt aaaattatta gtaattgaat tcaatatgtg
     4321 ttttaaattt gaagaagttg atatttctag atattgttct cgcttatgga ttctataatg
     4381 attgaataaa acgaatcttt ctattacatc atcatcttca tatctaatgg ttaaattcaa
     4441 catcttttta tacacattat ctaaatcatt agcaaatcta ttaatattac gtgtttctgg
     4501 actataatta cttaattttt ttaattcatc aaaagacaaa cgtaatgtat tagtatcttg
     4561 ctcttttaat ttattacaca tcgcaaaaaa taaattaatt tcagtagctg taaatcgcct
     4621 taatggaact aaattcattt catttttata tacaactgtc tctcctgtca tgatacagcc
     4681 ccctttatta cgaacctaaa ggagtatcgt ttgaatatac actcccattt gaaaactttt
     4741 attcacaata aactacttta ttatcaatgt caaaccataa aaggagtaca actttttaaa
     4801 acactccttt tatgtggcaa aaacactcct tttatgtggc aaaaacactc cttttatgtg
     4861 gcaaaaacac tccttttatg tggcaaaaac actcctttag gcattgaaat cccttgttgc
     4921 tctagggctg aacaagcccc taaaaaggtt tttaaaaaga tttataaaaa tatattaaaa
     4981 agttcgaggg gggctaccta tttttcatcc taaaaaataa ttaacctcaa acaaatgcat
     5041 ttaaatatct atttttataa tgtataacca tcttctctat cttctttaaa aatgatttct
     5101 cgttcttgtg cttgatattt cttcttaaag aactgttcat cattgttatc tatcgtcatt
     5161 acttcacgta ttttagaatt gtctaaatga ttatcaatat gatttattag tgtatgataa
     5221 cgctcttctt tcatcatact tttaatgatt ttaaaaactt gattgaataa cttaagcgta
     5281 taatttagtt ctttatcttt cttttcattc tctgacaaca aataattata acgttgtgct
     5341 aaatcattaa attcttcaac cagcttttca ttttccatat ggacactagt caattcatta
     5401 actaaacttt cattttgttt ctctgctttt tttaatgact tcccactttt aatacattca
     5461 taatcatcta atatcatctg tgctgcttta atttgtttag tgtatttttc aaaatcagtt
     5521 ttagtaatta caatattgcc tgtttcttgc ttctctttat gaaaccatcc acctacattt
     5581 ttagttttaa tttcatacat gacactcaga agctttttaa gcgtatctaa tgatttttgg
     5641 tagttttgta tcaatttatc attttcttgc tttaaataat cctctatttg cttctagcgc
     5701 atatgcattt gtttatgata ttctgttttt tgtttataac ggctaacttg atcatgtttt
     5761 tcttttgtaa gttgtctaga aattcctcgt tttaaatcat agccttgctt attaatatac
     5821 gtattgaatc tatcttggaa ttcggttaat gcttttttat tacctacaac ttctttcgca
     5881 cttaaacgtc catctttagt aataggaact acgccataat gcatatgtgg tgttatctca
     5941 tccatatgta ctgtcgcata taaaagattt tctttaccgt attcttcttc caagaacgct
     6001 ttagcatgct taaaaaacta ttttgtctct tcttcagata attgattaaa aaacacatta
     6061 tctgatgtaa ttaatccatc aatatgttta atggcatctg ttctaatttt gcgtttccct
     6121 ttataatttt tttcgatttt ctcatcaatt tttttattaa aatcaaactt agtatcattg
     6181 actaaatcat agtttaaata tgacttactt aaatcaatat ctatattttc ataattttta
     6241 ttttctcttt gaatatgtct ttgaatacct cttgtatttg tttttgattt cactttaaca
     6301 actcgaataa ttgaataaga cataataaat caacttccac tgcatatgat tataacacct
     6361 aaacacagaa aagttttaac atactagact tattaaaaac caaataagtc attaaaaacg
     6421 tgtgctctgc gaggcttgtt ttttgtcatc ataaaaaagg actggaaaat ccagtcctta
     6481 aattaaaaaa ctcaaaagta atgactaatc atatttcata ttgttttttc tctatgtatg
     6541 gctataccta tcaatatttc ttaacttcta agctcagaaa tattgactat gacatcaaat
     6601 cgtttcgcaa gctctaaatc atgcgttacg acaatcatag ttttattttc atcaagtagc
     6661 ttcaataata aatcaataac tatttttcca tttttcgtat ctagtgaccc agtaggttca
     6721 tcagctaaaa tgattttcgg atcttttaat attaatcttg ccaatgctac tctttgttgt
     6781 tcaccaccgc ttagagaact aacaattctt ttgatatcta aatctaggcc gacctttttt
     6841 aatacttctt tctttaagtt catattatct tttttattct ttttgaactt tagggctaaa
     6901 tctaaatttt gactgattgt ttgattttca agtaaagcaa aattttgaaa caaataccct
     6961 aacgtatatc tataaaaatc gactttcttt tttagtaact tatcttcaat atatatgctt
     7021 ccttgtgata catcttcgaa cccagcgatt atgttaagta aagtagattt tccagcgcca
     7081 ctttctccaa ctaaagcata tgattttcct ttttcaaaat taaagttaca tccgtctaaa
     7141 atgtttttat tacctttttt tacaaaaaca ttttcaagtt ttatcactat cggtcacctc
     7201 attttaaaaa gctaggaata tcttttgtaa tgtattctat cgaacgcaca tatttccctt
     7261 tatgatttac tttcacatat tcttttgtag gatcataacc taaaaaatcc aatttataac
     7321 tctttttttc tccattttta gagtatacag ttatatttct atagtcctgg gtatcttttg
     7381 gaactttggc ataagatact ttttctttta acagtgggtt aaaacgatct aaatgctcat
     7441 ttctaaccaa taacagacta agtatgatga ttaatagtac aattgttaca ataattaaag
     7501 ttcttttcat tgtttaaatc tccctcatta aatctttaaa gtatttttca agatatttaa
     7561 tataagcaat ttgaagtaaa tgttgaataa tagcaataga cattattatg aatagtaata
     7621 tctttgaacc aaataaaata tgcgtagtgt aagctaacat aatagaaagt aagatagaaa
     7681 ttgttaaata acgtacatta ctgctgaata atgaataacc atgaattttt cttaataata
     7741 gttgcttttt attccagcta aaatattgaa ttgtttcaaa tacagtagct atcaaaagaa
     7801 tgaaaacgtt aataataata gtaactattg ttattatcat ttttgttttc gtttcattta
     7861 attcatttaa cacagaatcc ttgtaattag ttataccgct aatttcttct tctaggtgat
     7921 tatctttaag caactgttta agtgtatcta aatctttaaa tagatatcca ccttgagaaa
     7981 cagcagctaa ataaaaatct cctgttaaat cgtcaagtgt caacaacatt actattggag
     8041 aatctagata cccaaatttc aaattagttg tgcgatcaaa agaaaaaaca gatacgtttt
     8101 ttgacagtac ttgcacatct acttttttgt tttgttgctt ttgaaagtca atccatcctt
     8161 ggtgattttt ttgaatttca gatttttgat attgtaacct tggaggaata aacacgttta
     8221 ttttatccga atgattgtca atcattttaa aatcatgatt tatattttta tagaaattca
     8281 gaaaattgtt attgataaaa aagacattgc cattttcagg aatgtaattg tttttatcgg
     8341 gattggctat attattattc tttaaaagca atccaccaag ttgttcgctt ttcttaatta
     8401 aattgtatat attagtttct aaaatttgtt tttcttctga atttctaata ttaggagaaa
     8461 tctctaatgt atagtaatta tctaactttt gccagatttt ttcagagtca tatatattct
     8521 ttaacttcgt ataagcattt aaattttgtg ccagtaaaaa agatagtatt agcaccatga
     8581 tacatttggt gaaggtaccc ataaatattg aaaacttata tccttttttc ccttttaaga
     8641 ttaatggaat acttaacttc aaaagaagac tatacgaaat cagccacagc aatgtagtaa
     8701 tacaagcaaa aacaaaaagc aacacgataa atctacgaat aaacattaag aaatccaatt
     8761 ctaaattggc tatatgaatg attaatatat tagcaataaa gaaaatagcg gtaagtacta
     8821 gccaataaat gatttttata tgaatattat gaaaaataat gcgtgtagtt gaaaagccat
     8881 gtagcttttg aatagcataa aatttcaaat tatatcctct gtcatataag aagtacaaaa
     8941 gatataatac gcctaagaat atgaaaggca ctaataaatc attatctatg actaattcaa
     9001 aaaataatat gtttctattt atgtattcaa cttcagatgt taaaccagct ttttttaatt
     9061 cactcgtaag ctcttctaca ttgaaatgtt caccaataat ataatacttt ccttttatct
     9121 ctctgtttaa taaatctgat ggagttaaaa gtgatgtttt attacgtata aagtcagaat
     9181 tatttcgttt tgagttgaaa acaaaaaatt cttttttatt atcaaaatct ttaacggatt
     9241 taattatttg tatattttga tttttggcgc ctgattcaat gacatctaac acttttgatt
     9301 tactgttaga tttatcccaa ttagagattg ttaaaatatt ggaactttca ggtataattt
     9361 cttcattttc tttgaagaaa aataaaaata atagccctga aattaataat aaagtactaa
     9421 aatctaaaaa taatttgaat tttttcatat tgcctctttc aagagaatag acagaattaa
     9481 gtttacttaa ttctgtctat tctccttaat taatatatgt aattagtgaa gactataaaa
     9541 tgttttgttt ccaccccaag cctttggagc agatgcctta gattgaacac caggtcgagc
     9601 aacaccacta aaagatgaat atttccctac tgctgttgaa ccatgatttc ttttattgtg
     9661 actataataa gaccatacgt aatgttttcc aataccatgg ctccaaacac caccagctac
     9721 atgtactgtt gcagcttcag ctttataagt tacacctaat aaagtgccga ataagattgt
     9781 actagcaata caactagaaa caaatttctt tttcataaaa acacctacat ttaatattct
     9841 ttatttatta tagcaaaaat aaataaaata gagaatgagt aaaaataatc taaaagtgtt
     9901 ttttctgctc tgttgcttgt tttgttcatc tatatataat attaattcta ttatccttaa
     9961 attaactatc attaaacaac gatatgacaa tgtataataa atacaatttc actacctata
    10021 attcaacatt atataaacta aagtatttca aataattaac tgtattaata ctctcatcat
    10081 gattgcgtta taaacattcg ttaatgagaa aaagagagag catatttacg ctctcttttc
    10141 ttgtcttatt attaaaaact cataatagat tataatcatc tgttttgaga cgctgtgaga
    10201 agctctcagt tgcattgaaa caaagtttat taaatcaaat cattatcgtt tttaattctg
    10261 taaatcgtct gccttgttat atttacttct ttcgcaattt tactaattga ttggccttct
    10321 tctaacattt ctacaacgcg atgataaata atacgtttct gtggatcttt agcatttggt
    10381 gaataaagta aggggcgccc tttatatacg cctttttcct tcgcaacttg aattccttgc
    10441 gcttgtcgac gtttactttc atttctctct tgttctgaaa ccattgctaa tatttgaata
    10501 attaaatctt tcataaactt atccagtaat ggattgccaa ccacttcatt catcataggt
    10561 aagctagtaa tcattaattg tacttctttg tcttttaaat aattaacggt atgaatcact
    10621 tcatcataat tacgacctaa acaatcaatg gattctacta caaaccgatc tcccatcctc
    10681 aaaaagttaa gtgcttcttg aagtactggt ctattttcaa tagatttccc agactgtttt
    10741 tctgtaaata ttttttcagc acaaaacgtc tttaaatttt caagttgtct ttctaaattt
    10801 tgatcgttcg atgatactct cgcatagcca acaatcattg atttccatct cataattaat
    10861 atacacccta atcatacgtt tcagttacta taaattcaac aattatgtca ctttgcttga
    10921 tatatgagaa ttatttaacc ttataaatga gaaaaaagca acgcacttta aataagatac
    10981 gttgcttttt cgattgatga acacctataa ttaaactatt catctattat ttatgatttt
    11041 ttgtatatac aatatttcta gtttgttaaa gagaattaag aaaataaatc tcgaaaataa
    11101 taaagggaaa atcaggtttt gatatcaaaa ttatacatgt caacgataat agaaaatata
    11161 atacaaacta taagatgtta tcagtattta ttatgcattt agaatattaa aattccttca
    11221 ttacactctt ggcggtttca cttatcaact tatcatttgg cttatcactt ttattgtctt
    11281 tattcgtaaa aatgactaaa acaataggtt cagattggcc cttaggataa acaaaagcaa
    11341 catcatttct agaagcatat gttattgctt gaccactttt atcagcaacc ttatagtctt
    11401 ttggaacacc atctttaatt aaagtgtctc cgtttttatt attaaacatt aaatcaagta
    11461 agaaattttt attttttttg cttaattttc catttgcgat aagtttattt aaagtcttgc
    11521 cgaaagcagc aggcgttgaa gtatcttttt tgctctttgg cgaatagtaa tttaattcta
    11581 tctcatatct aactggattt gttactttat ctcctagttc ttttagacgt tgtttaactt
    11641 ttttgattcc accgatttct tttataattt tattgtttgc tgtattatca ctatatgtca
    11701 ttgaagcctc aataagttct tttaaagtga tgtcttttcc tacatatttt tctaaaatag
    11761 gagaataagc aactatatca tctttgttaa tatgtacttt tttatttaac ttattataag
    11821 gtacttgttc taacaaaata gcactattta tcgcttttga agtcgaagca taggcaaatc
    11881 tcttatctga attaaatttt acttccttac cacttttagt atctaaagca taaacaccaa
    11941 tatgagcatt atattttttt tctaaatcat ttaactcttt ggcatgtgaa ctgtttgaat
    12001 tacatgcact taaaactaaa gccattacaa ttaaaaatat taactttttc aaaataaacc
    12061 ctccgatatt acagttgtaa tttttacaaa acaataatat tacaattgta atattgatgt
    12121 caattgttta ttataaatat ttgaaagaag gtgtcaaaat ggctaaatta ctaataatga
    12181 gtgtagtaag cttttgtttt atatttctat tgttagtatt ttttaggtac atattaaaac
    12241 gctattttaa ttatagttta aattataaag tttggtatct aactgtgctt gctggattaa
    12301 ttccttttat cccaattaaa ttctctttta taaaatttaa taatgtgaat aatcaagcgc
    12361 ccacagttga aagtaagtca cacgacttga accataacat aattaccacc aaacctgttc
    12421 aagagttcgc aacagatatc cataagttta attgggattc aattgataat atctgcacag
    12481 ttatttggat agttttagtt attattttaa gttttaaatt tttgaaagcc ttattatatc
    12541 ttaaatattt aaagaaacag tcactttatc taaacgaaaa tgaaaaaaat aaaatagata
    12601 cgatactttt caaccatcaa tataaaaaaa atattgtgat tcgaaaagca gaggctattc
    12661 aatctccaat aactttttgg tatgggaaat atattatttt gattcctagt tcatatttta
    12721 aaagtgtaat tgataaaaga ctaaaatata taatactgca tgaatatgct catgctaaaa
    12781 atagagatac tttacattta attatcttta atatcttctc tattattatg agttacaatc
    12841 cattagtaca tattgtaaaa agaaagataa ttcatgacaa tgaagtagaa gccgatagat
    12901 ttgtccttaa taatattaac aaaaatgaat ttaaaactta tgcggaatct attatggact
    12961 ccgtattaaa tgttccattt tttaataaaa atatattaag ccattcattt aatggtaaaa
    13021 agtcattact caaaagaaga ttaattaata taaaagaagc cgatctgaaa aagcagtcaa
    13081 aattaattct aatttttatt tgtattttta ctttttttat catgataatt caaagccagt
    13141 ttttaatggg gcaatcctta actgattata attataaaaa gcccttacaa agcgattacc
    13201 aaattttaga tgaaagtaaa aattttggtt caaatagtgg atctttcgtt atgtacagca
    13261 tgaagaaaga caaatactat atttataatg aaaaagaaag tagaaaaaga tattctcctg
    13321 attcaactta caaaatttat ttagcactgt ttggacttga ccgtcatatt ataagtgata
    13381 aaaattcacg tatgtcatgg aatcataaac attatctttt cgagtcttgg aataaggaac
    13441 aagatttaaa tacagcaatg caaaattcag ttaattggta cttcgaacgt attagtaatc
    13501 aaataccaaa gaactatact gcggctcaac tcaagcaatt aaattatggt aatgaaaatt
    13561 tgggaagtta taaaagctat tggatggaag atagtttgaa aatatctaat cttgaacaag
    13621 taatagtttt taaaaatatg atggaacaaa ataaccattt tagtaaaaaa gcaaagaatc
    13681 aattatcttc ttcattattg attaagaaaa atgaaaagta tgaactgtat gggaaaacag
    13741 gtacaggtat agtaaacggg aagtataata atgggtggtt tgtaggttac gtaattacaa
    13801 atcatgataa gtattatttt gctacacatt tatcagatgg aaacccgtct gggaaaaatg
    13861 ctgaattaat aagtgaaaaa atattaaaag gaatgggtgt tttaaatggc caataagcaa
    13921 gttgaaatat ctatggctga atgggatgtt atgaatataa tatgggataa aaaatcagta
    13981 tcagctaatg aaattgtagt tgaaattcaa aaatataaag aagttagtga taaaacgatt
    14041 agaacattaa tcacaagact atataaaaaa gagattataa aacgatacaa atcagaaaat
    14101 atttattttt actcatcaaa tattaaagaa gacgatatta aaatgaaaac tgctaaaacc
    14161 tttcttaata aactgtatgg aggggatatg aaaagtttag tgttgaattt tgcgaaaaat
    14221 gaagaattaa ataacaaaga aattgaagaa ttgcgagata ttttaaatga tattagtaaa
    14281 aagtaattag aggtatgttt caaacataat acatatgtaa actatgcttg actcttatta
    14341 aattagtttt gttaatgaca tttaaaatat attattaaag atgagagtgt acagaaaata
    14401 accattttct gtacactctt cttttatgtc taaataagta agaattacat aggattatgt
    14461 gttcaaaaac ccaataaaaa atctatgttc ataaaaggcc ttgtaattaa gttatggtac
    14521 actgaagatg tatataggag gtttgtattt tgaaaatagg ttatgcaaga gtttcaactg
    14581 gattacaaaa tttaaattta caggaggatc gattaaatac atatggttgt gaaaagatat
    14641 ttaatgacca tatgagtggt tcaaaaagta aaagacctgg tttagataaa gcaattgaat
    14701 ttgcgaggtc aggagatacg attgttgttt ggagattaga tagattggga cgtaatatgg
    14761 aagatttaat cacattagtt aatgaactta atgagagaag cgtgagtttc catagcttag
    14821 aagaaaatat aaccatggat aaatcaagtt ctacaggaca attattattt catttattcg
    14881 cagcatttgc agagtttgaa cggaatttaa ttttagaacg ttcttcagct ggcagaattg
    14941 cagcacgtgc tagaggccga tatggaggca gaccagaaaa attaaatcaa aaagatttaa
    15001 acttacttaa gacactttat gataatggca cgccaatcaa gacaattgca gaacagtggc
    15061 atgtttcacg tacaacaatt tatcgttacc tcaataaatt ggaggacaag aaagatgaaa
    15121 aacaaggaga agtatctaac taatttttct gaagccaaac gtaaaaaagc tactcaaaag
    15181 tacaatatta taaaaccttt tatcctaggc gaacaatctt tatcaagtat ttctgaaagt
    15241 aaagggattg cgttaagcac cctttatagg tggaataagt catataaaga acaaggactt
    15301 aaagggctaa tctatgcgac aagagctgat aaaggaacac gtaaaataga accaaagata
    15361 attgatgaaa ttgaacgcct tgcgcttatg aataaaagaa atagtatagc cacaattcat
    15421 aggaaaatca ctaattactg taaagaaaat aattttgata taccaagtta taaacaaatt
    15481 tatagtgtta ttaaagcgat gcctaagtct gttattgatt tctctcatca gggtgaaaaa
    15541 tactatcaaa ataagtacga tttaatacaa attagagaat cctcgagacc caatgaaata
    15601 tggcaagcag accatacttt gctagatatc tttatattag accaaaaagg taatatcaat
    15661 agaccatggc taactattat tatggatgac tatagtcgtg caattgcagg ctatttctta
    15721 agttttgatg cccccaatgc tcaaaacaca gcattaacac tacaccaagc aatatggaat
    15781 aaaaatgata ccaattggcc agtgtgtggt atacccgaaa aattctacac agatcatgga
    15841 agtgacttta cttcacatca tatggaacaa gtcgctattg atttgaaaat taacttgatg
    15901 ttttcgaaag ttggtgttcc tcgtggtcgt ggaaaaatag aacgattctt tcagacagtt
    15961 aatcaaactt tcttagaaca actgcctgga tatataaaca ataatgatac tcctagtaat
    16021 ctaataaatt ttcacaattt tgaagaaaaa ttacgttact ttttaattga agattataat
    16081 caaaaagaac atagtactat ccataccacg cctatcagtc gttggaatag taatcacttt
    16141 ttccctaata tgccaagtag cttagaacaa cttgatttat tattgttgga aatacctaaa
    16201 tctagaaaag ttcattcaga tggcattcat tttcaaggtt ttcgatacag taatactaat
    16261 ctagcagctt atgtaggtga atatgtactg attcgttata acccaaatga tatggctgaa
    16321 atacgtgtgt tttatagaga tgaatttctt tgtactgcta tatgtccaga aatagctgat
    16381 tactccatag atataaaaga cttacagcac gctcgtagtc agagaagaaa acacttaaaa
    16441 caaaatattg ctagtccaag taccacggaa ttaattaaga aagaaaaaaa ttgtggttat
    16501 tcacctcaag aaacgactaa aaacgtcaaa aaattaaaga ggtatcgtaa tgactaaaaa
    16561 tcaaaatttt attgaaacga aagagtataa acgctttgct gaattttgtg atgcttgtat
    16621 taaatatcag tatattggta tatgttatgg tcaacctggt gtcggaaaaa ctttatcgtc
    16681 taggtattac acaaattggg atactattga aaaacaagtt aaccatagag gttgggaaga
    16741 tttagctagt aaaacgaccg atgacatact atcggtggat aaaatatttt ataatgcacc
    16801 agcagaaaaa caaactaaat taaggaatga tttatatagt attactgcaa tcattgattt
    16861 gggtcaaaaa ttacatgttg taaataagta tggacatgaa catagtaaac attatagtga
    16921 tatgtttaaa tatattgatt taattatagt agatgagatt gatcgcctta aagtgcaaca
    16981 tttagagcaa ttaagagcta tttatgatga acataattta gcaatgatat ttattggtat
    17041 gccgggtata gagaaaaaac tatctcgtta tcctcaacta tattcgcgta taggttttgc
    17101 gcatgaattt gataatctaa gtaaagatga gacgcatcat atattagaat ataagtggca
    17161 agacttagga tttgatttaa aactcgaaga ctttactgat tatgaggcaa taacgacgat
    17221 tattaaaatt acaaaaggga attttaggct gattcatcgt ttatttgcgc agatagacag
    17281 aattatggat ataaatggtt tagataaaat aagtacagaa gttgtagaaa cagctagaga
    17341 tagtttagtt ataggtattc gataatagaa aaagcaacgc attttaatat agtgcgttgc
    17401 ttttctcatt tattaggtaa agtcattctc atatatcgag taaagtgaca acaattatat
    17461 atgtatgatt agggtgtact tatatcattc atataaatgt ttatttatac cctcaataaa
    17521 aatattatat gcttttaagc acctatcaca ttccttataa aaatgtttat tcaatccttt
    17581 aatatcgact agcgtagtct tataattttt ttgtaacaat tttaaatcct cttcgtaaaa
    17641 gcttaattta aaatgaccgg cttgagctaa tggctttttt ccttgtttaa ttaaaatcaa
    17701 tatgtttttt aaatgtttta aaaagttttt ataatcataa acttttattt tcatgaatga
    17761 tttatgtgga ttattttcat aatttagcag gtagttttct atatcttcaa tataactatc
    17821 atcaaatggt gtgtgctgga aataaaaagt ttttacatac atgaatattt tataaagttc
    17881 ttctttcaaa aaatcatatg tatctaaatc tctttgtata gcatccaatt tttttaaatt
    17941 ttttacattt ttaccacaat cctgtactct tatccatcca ctattttctt taatttcact
    18001 aggtacactt tgcattaaag tctgagatac tttacttttt aattccgaaa tatcattaat
    18061 atttggacta attagtctat tttctttaac ttttgtctta aactcatcta attttttaga
    18121 cttttccgcg gattcggtag atgctttatt catctcaaaa acatatatag gtttacctaa
    18181 agatttagca aaattgtact ccatttctgt atagctaata ttttcttcac tatcaattgt
    18241 tccataacta gaacctaaca ataatatcac tgcatctgat tcattgatcc attgtgttat
    18301 tatttcccat tggcttttac tacttgagtt aaaaagttcc atacctgctg gaatattatt
    18361 actgtttaaa actgcttcta ctactgcttg acgctcttct attaaatcta aataagttga
    18421 tgaaataaaa atttgatatt taattttagt attactcata tatgctcctt taataaaaaa
    18481 tcaatttaca taaatatatc atatgataat atccaaaaag actacttaaa atattatctt
    18541 tttgcattcc tctactaacc agtgttataa tctagataac gaaaatgatt aacaattaat
    18601 gcaccaatcc ccacactact gcaatagtgt ggggattttt tcgatgctgg cttataaagt
    18661 cgcctattaa ttatttgttg cgtttactaa gccaataagt ataatacgca acagcacagc
    18721 cactgatgac tggtgctatg atgtgaacga aaatgattag caaagtaatg cacctcctct
    18781 ctgcgtctga attgacgcct gagagatagg cgacctgtat attatatcat ctccgaatat
    18841 acgatgatag ataacttccg ataagtcgtc ttatgttata taactttgtt ttttatagta
    18901 tcaagacaag aagaaactcg tttcactcgt ttcaaaaacc ctcctgattt ttagagaaaa
    18961 actctcttat ttcatcgtct ttaataaaat aatatgccat ctttccatct ttataaaaat
    19021 caagtacctc atttttatat aaaagcctta aatgatgtga agttgaagca acactcattt
    19081 tcaatatcaa agaaatatca caaacacaca actcatcttc tttaatcaaa gataatatga
    19141 ttttcaattt cttctcatca caaatttttt ctaaaatgtt aagtaatttc ttagatttat
    19201 catcttctaa aaaacttaaa gcattgttaa ctttatcctc atgtacacag atcacatcac
    19261 aagtattttc ataactcata taaaatcaca ccctaaatta aaatataaat cctaaaattg
    19321 tttgaatagt gtcattttca ataataataa ataaacctaa agctatataa atgatagcca
    19381 taatccaacg actaaatttc tcaacaattt ctccaattcc tgggatatta gctaattttt
    19441 gtgcagtaaa caccaagaag aaaattaaaa ttaaaaagac aaacagagta agtaataaat
    19501 tagtaacact taatgtcaca aaatacggaa caaataaacc aatattatcg gcgccacaac
    19561 ttgctatcgt aacaattgca accgtaccaa ctaatttaga caatcctttt tcattcaatt
    19621 cttttttagc tctcttttct ccttcacaat catcataaat agccacttta attccaagat
    19681 aaattggtat taaacccaat aaacctaata tccacttttc tggaacataa tttaatacaa
    19741 aagctaaaaa caaactaact aatattaaaa taatagaccc taaatattga ccaacataaa
    19801 tatttctata ttcttttcta gtctttgctc tagcaaaaaa tattaataaa attactaata
    19861 aatcaactgc tgtagcaata taaagaacag cagcagcaac aaccgtttga atcataatac
    19921 acctcattca aaaatatttt tgaatgtatt ataacttata tttttaaata atcataggtg
    19981 ctttattcca attgctttat tgacgttgag cctcggaacc cttaacaatc ccaaaacttg
    20041 tcgaatggtc ggcttaatag ctcacgctat gccgacattc gtctgcaagt ttagttaagg
    20101 gttcttctca acgcacaata aattttctcg gcataaatgc gtgtctatgc gtagacatgg
    20161 agacacttca gaattatgga gtgattacat gagtttaact atttttcttt attcagtttt
    20221 aggaagttta ttagcaaatt atatctacga aaaatcttca aaataaataa ctttttcggt
    20281 tctactttgt acactttatc tacctggtag acctaattgt tattgcttta caggtctaaa
    20341 attcgtcgtt ataatctagt taaatcccgt aagggcgcac ttatacgtcg gataaatcga
    20401 catgtgcaaa aacgtaatcg accttcgtcg atttttttat ttcaaaatta aagaaacggc
    20461 ttgagatatt ccgagcagtt ataaaaatta atttgcgttg aatattgcta ctacattctt
    20521 gaaaaagtga tgtagattta tagcccataa cttttttgaa ttacatcgac gatacggcgt
    20581 cgaaagaaaa agctacctca ctttatctgg gggggctttt attttttatg cccttatttt
    20641 gaattttaag agggcatttt aaagatttag gggtgattca tatagtttta tatctaaaac
    20701 ttatatacgc ttttaaaacg caaatatga
//
