LOCUS       NZ_CP120015            20724 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Staphylococcus aureus strain Dog152 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP120015
VERSION     NZ_CP120015.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33696832
            Assembly: GCF_034043035.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20724)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Canine Staphylococcaceae circulating in a Kenyan animal shelter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20724)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
  REMARK    Annotation added by database at the submitter's request
REFERENCE   3  (bases 1 to 20724)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Flye v. v2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 662x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/06/2024 11:15:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,737
            CDSs (total)                      :: 2,655
            Genes (coding)                    :: 2,588
            CDSs (with protein)               :: 2,588
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 33 of 67
            Pseudo Genes (incomplete)         :: 33 of 67
            Pseudo Genes (internal stop)      :: 20 of 67
            Pseudo Genes (multiple problems)  :: 18 of 67
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20724
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Dog152"
                     /isolation_source="nasal swab"
                     /host="Canis lupus familiaris"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya:Nairobi"
                     /lat_lon="1.3345 S 36.7331 E"
                     /collection_date="2015-06-27"
                     /collected_by="Joerg Jores, Anna Lacasta, Anne Liljander,
                     Paul Ssajjakambwe (International Livestock Research
                     Institute, ILRI)"
     gene            join(20254..20724,1..150)
                     /locus_tag="P3U01_RS13555"
                     /old_locus_tag="P3U01_13555"
     CDS             join(20254..20724,1..150)
                     /locus_tag="P3U01_RS13555"
                     /old_locus_tag="P3U01_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_323715463.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEGSLDTK
                     NGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ATP-binding cassette domain-containing protein"
     gene            388..1017
                     /gene="mobV"
                     /locus_tag="P3U01_RS13560"
                     /old_locus_tag="P3U01_13560"
                     /pseudo=""
     CDS             388..1017
                     /gene="mobV"
                     /locus_tag="P3U01_RS13560"
                     /old_locus_tag="P3U01_13560"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            1111..1656
                     /locus_tag="P3U01_RS13565"
                     /old_locus_tag="P3U01_13565"
     CDS             1111..1656
                     /locus_tag="P3U01_RS13565"
                     /old_locus_tag="P3U01_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            2040..2900
                     /locus_tag="P3U01_RS13570"
                     /old_locus_tag="P3U01_13570"
     CDS             2040..2900
                     /locus_tag="P3U01_RS13570"
                     /old_locus_tag="P3U01_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            2987..3328
                     /locus_tag="P3U01_RS13575"
                     /old_locus_tag="P3U01_13575"
     CDS             2987..3328
                     /locus_tag="P3U01_RS13575"
                     /old_locus_tag="P3U01_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(3567..3638)
                     /locus_tag="P3U01_RS13580"
                     /old_locus_tag="P3U01_13580"
     CDS             complement(3567..3638)
                     /locus_tag="P3U01_RS13580"
                     /old_locus_tag="P3U01_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3787..3972
                     /locus_tag="P3U01_RS13585"
                     /old_locus_tag="P3U01_13585"
     CDS             3787..3972
                     /locus_tag="P3U01_RS13585"
                     /old_locus_tag="P3U01_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(4191..4934)
                     /locus_tag="P3U01_RS13590"
                     /old_locus_tag="P3U01_13590"
     CDS             complement(4191..4934)
                     /locus_tag="P3U01_RS13590"
                     /old_locus_tag="P3U01_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            5345..6021
                     /locus_tag="P3U01_RS13595"
                     /old_locus_tag="P3U01_13595"
                     /pseudo=""
     CDS             5345..6021
                     /locus_tag="P3U01_RS13595"
                     /old_locus_tag="P3U01_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <6032..6314
                     /locus_tag="P3U01_RS13600"
                     /old_locus_tag="P3U01_13600"
                     /pseudo=""
     CDS             <6032..6314
                     /locus_tag="P3U01_RS13600"
                     /old_locus_tag="P3U01_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            7526..8143
                     /gene="cadD"
                     /locus_tag="P3U01_RS13605"
                     /old_locus_tag="P3U01_13605"
     ARG             7527..8140
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            8162..8509
                     /locus_tag="P3U01_RS13610"
                     /old_locus_tag="P3U01_13610"
     CDS             8162..8509
                     /locus_tag="P3U01_RS13610"
                     /old_locus_tag="P3U01_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            8678..8770
                     /locus_tag="P3U01_RS13615"
                     /old_locus_tag="P3U01_13615"
     CDS             8678..8770
                     /locus_tag="P3U01_RS13615"
                     /old_locus_tag="P3U01_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            8982..9956
                     /locus_tag="P3U01_RS13620"
                     /old_locus_tag="P3U01_13620"
     CDS             8982..9956
                     /locus_tag="P3U01_RS13620"
                     /old_locus_tag="P3U01_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_054192782.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKNLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(10076..10891)
                     /locus_tag="P3U01_RS13625"
                     /old_locus_tag="P3U01_13625"
     CDS             complement(10076..10891)
                     /locus_tag="P3U01_RS13625"
                     /old_locus_tag="P3U01_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(10884..12326)
                     /locus_tag="P3U01_RS13630"
                     /old_locus_tag="P3U01_13630"
     CDS             complement(10884..12326)
                     /locus_tag="P3U01_RS13630"
                     /old_locus_tag="P3U01_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_054192781.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISESKGI
                     ALSTLYRWNKSYKEQGLKGLIYATRADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     ITNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDLQHARSQRRKHLKQNIASPSTTELIKKEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(12298..12891)
                     /locus_tag="P3U01_RS13635"
                     /old_locus_tag="P3U01_13635"
     CDS             complement(12298..12891)
                     /locus_tag="P3U01_RS13635"
                     /old_locus_tag="P3U01_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_054192780.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERSVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKKDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(13155..13535)
                     /gene="blaI"
                     /locus_tag="P3U01_RS13640"
                     /old_locus_tag="P3U01_13640"
     ARG             complement(13159..13535)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(13525..15282)
                     /gene="blaR1"
                     /locus_tag="P3U01_RS13645"
                     /old_locus_tag="P3U01_13645"
     ARG             complement(13529..15282)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="96.07"
                     /coverage="100.0"
     gene            15389..16234
                     /gene="blaZ"
                     /locus_tag="P3U01_RS13650"
                     /old_locus_tag="P3U01_13650"
     ARG             15390..16231
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16603..17211
                     /locus_tag="P3U01_RS13655"
                     /old_locus_tag="P3U01_13655"
     CDS             16603..17211
                     /locus_tag="P3U01_RS13655"
                     /old_locus_tag="P3U01_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            17625..17918
                     /locus_tag="P3U01_RS13660"
                     /old_locus_tag="P3U01_13660"
     CDS             17625..17918
                     /locus_tag="P3U01_RS13660"
                     /old_locus_tag="P3U01_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            17993..19927
                     /locus_tag="P3U01_RS13665"
                     /old_locus_tag="P3U01_13665"
     CDS             17993..19927
                     /locus_tag="P3U01_RS13665"
                     /old_locus_tag="P3U01_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            19931..20242
                     /locus_tag="P3U01_RS13670"
                     /old_locus_tag="P3U01_13670"
     CDS             19931..20242
                     /locus_tag="P3U01_RS13670"
                     /old_locus_tag="P3U01_13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     ARG             15390..16234
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             12625..20724
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          6372..6519
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          2041..2900
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4192..4934)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          389..663
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 gggtcactag atacgaaaaa tggaaaaata gttattgatt tattattgaa gctacttgat
       61 gaaaataaaa ctatgattgt cgtaacgcat gatttagagc ttgcgaaacg atttgatgtc
      121 atagtcaata tttctgagct tagaagttaa gaaatattga taggtatagc catacataga
      181 gaaaaaacaa tatgaaatat gattagtcat tacttttgag ttttttaatt taaggactgg
      241 attttccagt ccttttttat gatgacaaaa aacaagcctc gcagagcaca cgtttttaat
      301 gacttatttg gtttttaata agtctagtat gttaaaactt ttctgtgttt aggtgttata
      361 atcatatgca gtggaagttg atttattatg tcttattcaa ttattcgagt tgttaaagtg
      421 aaatcaaaaa caaatacaag aggtattcaa agacatattc aaagagaaaa taaaaattat
      481 gaaaatatag atattgattt aagtaagtca tatttaaact atgatttagt caatgatact
      541 aagtttgatt ttaataaaaa aattgatgag aaaatcgaaa aaaattataa agggaaacgc
      601 aaaattagaa cagatgccat taaacatatt gatggattaa ttacatcaga taatgtgttt
      661 tttaatcaat tatctgaaga agagacaaaa tagtttttta agcatgctaa agcgttcttg
      721 gaagaagaat acggtaaaga aaatctttta tatgcgacag tacatatgga tgagataaca
      781 ccacatatgc attatggcgt agttcctatt actaaagatg gacgtttaag tgcgaaagaa
      841 gttgtaggta ataaaaaagc attaaccgaa ttccaagata gattcaatac gtatattaat
      901 aagcaaggct atgatttaaa acgaggaatt tctagacaac ttacaaaaga aaaacatgat
      961 caagttagcc gttataaaca aaaaacagaa tatcataaac aaatgcatat gcgctagaag
     1021 caaatagagg attatttaaa gcaagaaaat gataaattga tacaaaacta ccaaaaatca
     1081 ttagatacgc ttaaaaagct tctgagtgtc atgtatgaaa ttaaaactaa aaatgtaggt
     1141 ggatggtttc ataaagagaa gcaagaaaca ggcaatattg taattactaa aactgatttt
     1201 gaaaaataca ctaaacaaat taaagcagca cagatgatat tagatgatta tgaatgtatt
     1261 aaaagtggga agtcattaaa aaaagcagag aaacaaaatg aaagtttagt taatgaattg
     1321 actagtgtcc atatggaaaa tgaaaagctg gttgaagaat ttaatgattt agcacaacgt
     1381 tataattatt tgttgtcaga gaatgaaaag aaagataaag aactaaatta tacgcttaag
     1441 ttattcaatc aagtttttaa aatcattaaa agtatgatga aagaagagcg ttatcataca
     1501 ctaataaatc atattgataa tcatttagac aattctaaaa tacgtgaagt aatgacgata
     1561 gataacaatg atgaacagtt ctttaagaag aaatatcaag cacaagaacg agaaatcatt
     1621 tttaaagaag atagagaaga tggttataca ttataaaaat agatatttaa atgcatttgt
     1681 ttgaggttaa ttatttttta ggatgaaaaa taggtagccc ccctcgaact ttttaatata
     1741 tttttataaa tctttttaaa aaccttttta ggggcttgtt cagccctaga gcaacaaggg
     1801 atttcaatgc ctaaaggagt gtttttgcca cataaaagga gtgtttttgc cacataaaag
     1861 gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt tttaaaaagt
     1921 tgtactcctt ttatggtttg acattgataa taaagtagtt tattgtgaat aaaagttttc
     1981 aaatgggagt gtatattcaa acgatactcc tttaggttcg taataaaggg ggctgtatca
     2041 tgacaggaga gacagttgta tataaaaatg aaatgaattt agttccatta aggcgattta
     2101 cagctactga aattaattta ttttttgcga tgtgtaataa attaaaagag caagatacta
     2161 atacattacg tttgtctttt gatgaattaa aaaaattaag taattatagt ccagaaacac
     2221 gtaatattaa tagatttgct aatgatttag ataatgtgta taaaaagatg ttgaatttaa
     2281 ccattagata tgaagatgat gatgtaatag aaagattcgt tttattcaat cattatagaa
     2341 tccataagcg agaacaatat ctagaaatat caacttcttc aaatttaaaa cacatattga
     2401 attcaattac taataatttt acaaaatttg aattaaaaga aatgactagg cttaaatcta
     2461 catattctaa aaatatgttt agattactta aacaatacaa acatacaggc tatttaaaaa
     2521 ttcacatcga tgattttaaa aatcgtttag atatacctaa atcttatcgt atgactgata
     2581 ttaacaaaaa tgtttttaaa cctattatta ttgaattagg ttctatattt aataatctta
     2641 ctatcaataa aatcaaagcg aaaaaagggc gtaaaattga atggatagag ttcacatttg
     2701 acgctgagaa acgcattcat aacaaacgac aacctcaaat gtccaagata gataaatcaa
     2761 gacaatatgt gaggcgtgaa aagacgccta aatggttaga agaacggtca tatgaaaagc
     2821 aacctcaaaa agattacgac ccacaattag agaaagaacg agaggatttt ttaaaacaac
     2881 ttgaactgaa ttgggaataa cgcaactttt cgttgcgagt tggttaacta aaagtatcgt
     2941 gacttttcaa ttattttaat tatagtttga gttaaggagt gattttatga aattagctga
     3001 agctataaaa gaacagagag aattaaaagg atggtctcaa gaggaattag ccaatatatt
     3061 aaaggtttcc agacaaagtg tttctaaatg ggaaagtgcc aaaaactatc cttccttaga
     3121 tattttgatt gctatgagcg atttattcgg aatctcttta gagcatttaa ttaaaggaga
     3181 tgcacgtttt aaaaaagtta ttttagaggg aaattataga gagagtaaca gggtaccttc
     3241 catagttgat tttctttatg atttttggtg gcttttcttt cctgttgccg gatttttagt
     3301 ttgggccatt cattcgttca tgggttgatt ttaaaatcaa aatttaatgc acatcaggca
     3361 atatgaaaaa ggaaagtatt tttacgacac cttgaaatgt attgataaga atagaagagt
     3421 ttacaaaagg caatatgaaa tatatactaa aagtaacaag aatttcgttt gtaaacgcac
     3481 aaaaccccga actattcgcc gtagttcggg gttttttggt gaattggctt taatcgtcta
     3541 tattattttt tatcacgttt atggagctaa taaccaaata acgtaacgag acaaccactg
     3601 attgccgttg tcatgatgtg aacaagaatt tcattcataa atcgcacctc ctctttacgc
     3661 cgaattgaca tctgagagat agacgacctt cacattataa caaatctctc cttccatgaa
     3721 ataacatgaa tattaataaa tgttgttata tattaaagat aaataaatat aagggtggga
     3781 ttgataatgt ttggcgatca aagacaagaa gctacaaaat atgtcattaa agaaggttat
     3841 caagatattt atttcctcaa caaaaacggg gaatggtatt atttcgaagt aagaagtgtc
     3901 tggcgtggca aacatattat tagagttaaa gatggtttgt taggttggag aaaagaaata
     3961 gtaactgaat aaagatacaa aatacttgcc aatgcaaaag aatgaaaacg cgtcaaatca
     4021 acgatgtata aaagatgcat aaaagataat gaaagtaaaa agccataaat gccgtcatat
     4081 aggcatttat ggctttttgt ttggttaaca taatcgatga ttatcagaag ttcaattcac
     4141 ataaaaaagc acggctaatt tatgaacttg tcgtaccttt ttaattaaaa ttagttacca
     4201 aatagacgac tccaaaaccc ctttttaggt tccgtttctt cactcttttc ttctatatca
     4261 ctatcattgt catttggatt agctgaaacg tcttctcttt gtgcttcttc accttgtgta
     4321 ctttcgtcgc tttgacttcc agatatatcc ttatattgaa tctctgtttc tttagtttct
     4381 tcctgatctc ggttaatatt tacaggacta gtagtatatg ttttttcttg tgcatcaacg
     4441 ttttgtctag cgttagtaga tgtatcaaag ggataattaa ggtgtttttc tttttctaat
     4501 tgattttcta atttttgaat ctttttatta ctctctaatg ccagaacttg ctgattctca
     4561 agcaattttg atctttcttg caactctttt ctgtaaaatt caattgttgt ttcatgacga
     4621 ctttcttgtt tttcaatttg attatttaaa gtattaatct gatttttaag tatttctact
     4681 atttgagcat cgcttttaga ttcaaaatta atattatccg actctttttt ttgtttgtct
     4741 tcagtagcac tttcaaaacc atatttcttt ttattttcat ttactctttg aatgattttt
     4801 tctatatcgg tatcttcttt aataaacgaa gtgttttcct gttttattgt ctctatattc
     4861 aatctcttaa tattattaaa aatcgtttgc ttactaaccc ctaattcttc actcaacctt
     4921 tttacacttt tcatatcatc aaccctttat aaaatgttta taaaccctta gtaaaatatt
     4981 ataagcttat aacgattaat aataaagtaa tcgacaaata aaaatataaa ttcgccaacc
     5041 tttttatcaa gggtttgtaa agggtttatg gtgtttatca aaggtttata aacctatatt
     5101 ttcccttttt taagtttatt caaagtgcta taataacctt aatataacaa aaaccccaac
     5161 tactggtaat agtcggggtt tggtaataaa acgtttagaa actgtttatt tatataattt
     5221 tcgatactta gattatataa tgaataatat cttagtgcaa gcacctagat tattaaataa
     5281 acacaaaaaa tgtaagcgtt ttattacctc ttaccaaact aaaattcgga aagaggtttt
     5341 tattatgtca attaaacttt acaacataaa tgaggaatac agagaaaagt tttatcaaat
     5401 accgaaagta ttttttacaa atcctaaata tatcaagtta tccaatgatg caaaaatggc
     5461 atggggtatt cttagagatc gtttagattt atcaattaaa aatggttggg ttgattctaa
     5521 aacaggtaat atttattttt attacaaaaa tgaaaaccca caaaatatat taaattgtaa
     5581 aaaagataaa gtaattaaaa taaagaaaga acttaattga agccgaatta ctactacaag
     5641 aaagacaagg tttaaataag acaaataaac tttatttagt taaaccagaa gtaacagaag
     5701 atgatattta taaaattcaa aagcaagaaa acactgttga gagcagcaat ggcaaggaag
     5761 tcggaaaaac cgacttcaag aagtcgataa aacagaatct aatgatactg aacttagcta
     5821 tactgaatct aacaatactg aaataaatga tatgaatgac ttgaatgata tagagtccga
     5881 aaatgaaatt agtaatcatt caagtcaatg caaggttatt taatgcaaac aattttaact
     5941 gaatttgaag aaacacatgc actttatatg cgccgtaaaa acatgaaaca atataatatc
     6001 tttaatcaat cattcaaatg attttataac aatcaaagat acatcaaaat atttcgttaa
     6061 atcatctgac tttttaactg atagcgatga aaaaatcaag aaattgtcag tgatctagaa
     6121 aaagatttgt atcgaaaacg tatgttaagt tatggtggat tgcttaaata aaaacataaa
     6181 attttaaact tagacgatgc tgaagatggc aatttaatta atacaagtga tgaagataaa
     6241 atagcaaatg aagaagaaaa ggcacattcg attacggcaa ttttgaaaag caaaattatt
     6301 atttaaggca ttagtgataa ctgatgtctt tttttattac ttttttgtaa aaaaagtgct
     6361 gtcttatttt tgtgacaaat gctgtatgta gtgtcacaaa agtgtgacac ttgagctttt
     6421 tatgacccca cacaaaaaca ttttcgaagc cttgaaatat ctggctttgc cagatccccc
     6481 attcattgat ggggacaaat ttcccttatg ctcttacgga gattttagag ttaaattaaa
     6541 atttctaagt ttttgataag aaaagccctg caggaattta gaagaacgtg gggaagtttt
     6601 aaagaatttt atgctaattt ttaatttgca tgtaaatggg cagtgtctaa aaaatagtta
     6661 ttgtttttgc tcaaattttt gtttttgaaa atagcatata tttatttggc tcatatttgc
     6721 gttttaaaag cgtatataag ttttagatat aaaactatat gaatcacccc taaatcttta
     6781 aaatgccctc ttaaaattca aaataagggc ataaaaaata aaagcccccc cagataaagt
     6841 gaggtagctt tttctttcga cgccgtatcg tcgatgtaat tcaaaaaagt tatgggctat
     6901 aaatctacat cactttttca agaatgtagt agcaatattc aacgcaaatt aatttttata
     6961 actgctcgga atatctcaag ccgtttcttt aattttgaaa taaaaaaaat cgacgaaggt
     7021 cgattacgtt tttgcacatg tcgatttatc cgacgtataa gtgcgccctt acgggattta
     7081 actagattat aacgacgaat tttagacctg taaagcaata acaattaggt ctaccaggta
     7141 gataaagtgt acaaagtaga accgaaaaag ttatttattt tgaagatttt tcgtagatat
     7201 aatttgctaa taaacttcct aaaactgaat aaagaaaaat agttaaactc atgtaatcac
     7261 tccataattc tgaagtgtct ccatgtctac gcatagacac gcatttatgc cgagaaaatt
     7321 tattgtgcgt tgagaagaac ccttaactaa acttgcagac gaatgtcggc atagcgtgag
     7381 ctattaagcc gaccattcga caagttttgg gattgttaag ggttccgagg ctcaacgtca
     7441 ataaagcaat tggaataaag cacctatgat tatttaaaaa tataagttat aatacattca
     7501 aaaatatttt tgaatgaggt gtattatgat tcaaacggtt gttgctgctg ctgttcttta
     7561 tattgctaca gcagttgatt tattagtaat tttattaata ttttttgcta gagcaaagac
     7621 tagaaaagaa tatagaaata tttatgttgg tcaatattta gggtctatta ttttaatatt
     7681 agttagtttg tttttagctt ttgtattaaa ttatgttcca gaaaagtgga tattaggttt
     7741 attgggttta ataccaattt atcttggaat taaagtggct atttatgatg attgtgaagg
     7801 agaaaagaga gctaaaaaag aattgaatga aaaaggattg tctaaattag ttggtacggt
     7861 tgcaattgtt acgatagcaa gttgtggcgc cgataatatt ggtttatttg ttccgtattt
     7921 tgtgacatta agtgttacta atttattact tactctgttt gtctttttaa ttttaatttt
     7981 cttcttggtg tttactgcac aaaaattagc taatatccca ggaattggag aaattgttga
     8041 gaaatttagt cgttggatta tggctatcat ttatatagct ttaggtttat ttattattat
     8101 tgaaaatgac actattcaaa caattttagg atttatattt taatttaggg tgtgatttta
     8161 tatgagttat gaaaatactt gtgatgtgat ctgtgtacat gaggataaag ttaacaatgc
     8221 tttaagtttt ttagaagatg ataaatctaa gaaattactt aacattttag aaaaaatttg
     8281 tgatgagaag aaattgaaaa tcatattatc tttgattaaa gaagatgagt tgtgtgtttg
     8341 tgatatttct ttgatattga aaatgagtgt tgcttcaact tcacatcatt taaggctttt
     8401 atataaaaat gaggtacttg atttttataa agatggaaag atggcatatt attttattaa
     8461 agacgatgaa ataagagagt ttttctctaa aaatcaggag ggtttttgaa acgagtgaaa
     8521 cgagtttctt cttgtcttga tactataaaa aacaaagtta tataacataa gacgacttat
     8581 cggaagttat ctatcatcgt atattcggag atgatataat atacaggtcg cctatctctc
     8641 aggcgtcaat tcagacgcag agaggaggtg cattactttg ctaatcattt tcgttcacat
     8701 catagcacca gtcatcagtg gctgtgctgt tgcgtattat acttattggc ttagtaaacg
     8761 caacaaataa ttaataggcg actttataag ccagcatcga aaaaatcccc acactattgc
     8821 agtagtgtgg ggattggtgc attaattgtt aatcattttc gttatctaga ttataacact
     8881 ggttagtaga ggaatgcaaa aagataatat tttaagtagt ctttttggat attatcatat
     8941 gatatattta tgtaaattga ttttttatta aaggagcata tatgagtaat actaaaatta
     9001 aatatcaaat ttttatttca tcaacttatt tagatttaat agaagagcgt caagcagtag
     9061 tagaagcagt tttaaacagt aataatattc cagcaggtat ggaacttttt aactcaagta
     9121 gtaaaagcca atgggaaata ataacacaat ggatcaatga atcagatgca gtgatattat
     9181 tgttaggttc tagttatgga acaattgata gtgaagaaaa tattagctat acagaaatgg
     9241 agtacaattt tgctaaatct ttaggtaaac ctatatatgt ttttgagatg aataaagcat
     9301 ctaccgaatc cgcggaaaag tctaaaaaat tagatgagtt taagacaaaa gttaaagaaa
     9361 atagactaat tagtccaaat attaatgata tttcggaatt aaaaagtaaa gtatctcaga
     9421 ctttaatgca aagtgtacct agtgaaatta aagaaaatag tggatggata agagtacagg
     9481 attgtggtaa aaatgtaaaa aatttaaaaa aattggatgc tatacaaaga gatttagata
     9541 catatgattt tttgaaagaa gaactttata aaatattcat gtatgtaaaa actttttatt
     9601 tccagcacac accatttgat gatagttata ttgaagatat agaaaactac ctgctaaatt
     9661 atgaaaataa tccacataaa tcattcatga aaataaaagt ttatgattat aaaaactttt
     9721 taaaacattt aaaaaacata ttgattttaa ttaaacaagg aaaaaagcca ttagctcaag
     9781 ccggtcattt taaattaagc ttttacgaag aggatttaaa attgttacaa aaaaattata
     9841 agactacgct agtcgatatt aaaggattga ataaacattt ttataaggaa tgtgataggt
     9901 gcttaaaagc atataatatt tttattgagg gtataaataa acatttatat gaatgatata
     9961 agtacaccct aatcatacat atataattgt tgtcacttta ctcgatatat gagaatgact
    10021 ttacctaata aatgagaaaa gcaacgcact atattaaaat gcgttgcttt ttctattatc
    10081 gaatacctat aactaaacta tctctagctg tttctacaac ttctgtactt attttatcta
    10141 aaccatttat atccataatt ctgtctatct gcgcaaataa acgatgaatc agcctaaaat
    10201 tcccttttgt aattttaata atcgtcgtta ttgcctcata atcagtaaag tcttcgagtt
    10261 ttaaatcaaa tcctaagtct tgccacttat attctaatat atgatgcgtc tcatctttac
    10321 ttagattatc aaattcatgc gcaaaaccta tacgcgaata tagttgagga taacgagata
    10381 gttttttctc tatacccggc ataccaataa atatcattgc taaattatgt tcatcataaa
    10441 tagctcttaa ttgctctaaa tgttgcactt taaggcgatc aatctcatct actataatta
    10501 aatcaatata tttaaacata tcactataat gtttactatg ttcatgtcca tacttattta
    10561 caacatgtaa tttttgaccc aaatcaatga ttgcagtaat actatataaa tcattcctta
    10621 atttagtttg tttttctgct ggtgcattat aaaatatttt atccaccgat agtatgtcat
    10681 cggtcgtttt actagctaaa tcttcccaac ctctatggtt aacttgtttt tcaatagtat
    10741 cccaatttgt gtaataccta gacgataaag tttttccgac accaggttga ccataacata
    10801 taccaatata ctgatattta atacaagcat cacaaaattc agcaaagcgt ttatactctt
    10861 tcgtttcaat aaaattttga tttttagtca ttacgatacc tctttaattt tttgacgttt
    10921 ttagtcgttt cttgaggtga ataaccacaa tttttttctt tcttaattaa ttccgtggta
    10981 cttggactag caatattttg ttttaagtgt tttcttctct gactacgagc gtgctgtaag
    11041 tcttttatat ctatggagta atcagctatt tctggacata tagcagtaca aagaaattca
    11101 tctctataaa acacacgtat ttcagccata tcatttgggt tataacgaat cagtacatat
    11161 tcacctacat aagctgctag attagtatta ctgtatcgaa aaccttgaaa atgaatgcca
    11221 tctgaatgaa cttttctaga tttaggtatt tccaacaata ataaatcaag ttgttctaag
    11281 ctacttggca tattagggaa aaagtgatta ctattccaac gactgatagg cgtggtatgg
    11341 atagtactat gttctttttg attataatct tcaattaaaa agtaacgtaa tttttcttca
    11401 aaattgtgaa aatttattag attactagga gtatcattat tgtttatata tccaggcagt
    11461 tgttctaaga aagtttgatt aactgtctga aagaatcgtt ctatttttcc acgaccacga
    11521 ggaacaccaa ctttcgaaaa catcaagtta attttcaaat caatagcgac ttgttccata
    11581 tgatgtgaag taaagtcact tccatgatct gtgtagaatt tttcgggtat accacacact
    11641 ggccaattgg tatcattttt attccatatt gcttggtgta gtgttaatgc tgtgttttga
    11701 gcattggggg catcaaaact taagaaatag cctgcaattg cacgactata gtcatccata
    11761 ataatagtta gccatggtct attgatatta cctttttggt ctaatataaa gatatctagc
    11821 aaagtatggt ctgcttgcca tatttcattg ggtctcgagg attctctaat ttgtattaaa
    11881 tcgtacttat tttgatagta tttttcaccc tgatgagaga aatcaataac agacttaggc
    11941 atcgctttaa taacactata aatttgttta taacttggta tatcaaaatt attttcttta
    12001 cagtaattag tgattttcct atgaattgtg gctatactat ttcttttatt cataagcgca
    12061 aggcgttcaa tttcatcaat tatctttggt tctattttac gtgttccttt atcagctctt
    12121 gtcgcataga ttagcccttt aagtccttgt tctttatatg acttattcca cctataaagg
    12181 gtgcttaacg caatcccttt actttcagaa atacttgata aagattgttc gcctaggata
    12241 aaaggtttta taatattgta cttttgagta gcttttttac gtttggcttc agaaaaatta
    12301 gttagatact tctccttgtt tttcatcttt cttgtcctcc aatttattga ggtaacgata
    12361 aattgttgta cgtgaaacat gccactgttc tgcaattgtc ttgattggcg tgccattatc
    12421 ataaagtgtc ttaagtaagt ttaaatcttt ttgatttaat ttttctggtc tgcctccata
    12481 tcggcctcta gcacgtgctg caattctgcc agctgaagaa cgttctaaaa ttaaattccg
    12541 ttcaaactct gcaaatgctg cgaataaatg aaataataat tgtcctgtag aacttgattt
    12601 atccatggtt atattttctt ctaagctatg gaaactcacg cttctctcat taagttcatt
    12661 aactaatgtg attaaatctt ccatattacg tcccaatcta tctaatctcc aaacaacaat
    12721 cgtatctcct gacctcgcaa attcaattgc tttatctaaa ccaggtcttt tactttttga
    12781 accactcata tggtcattaa atatcttttc acaaccatat gtatttaatc gatcctcctg
    12841 taaatttaaa ttttgtaatc cagttgaaac tcttgcataa cctattttca aaatacaaac
    12901 ctcctatata catcttcagt gtaccataac ttaattacaa ggccttttat gaacatagat
    12961 tttttattgg gtttttgaac acataatcct atgtaattct tacttattta gacataaaag
    13021 aagagtgtac agaaaatggt tattttctgt acactctcat ctttaataat atattttaaa
    13081 tgtcattaac aaaactaatt taataagagt caagcatagt ttacatatgt attatgtttg
    13141 aaacatacct ctaattactt tttactaata tcatttaaaa tatctcgcaa ttcttcaatt
    13201 tctttgttat ttaattcttc atttttcgca aaattcaaca ctaaactttt catatcccct
    13261 ccatacagtt tattaagaaa ggttttagca gttttcattt taatatcgtc ttctttaata
    13321 tttgatgagt aaaaataaat attttctgat ttgtatcgtt ttataatctc ttttttatat
    13381 agtcttgtga ttaatgttct aatcgtttta tcactaactt ctttatattt ttgaatttca
    13441 actacaattt cattagctga tactgatttt ttatcccata ttatattcat aacatcccat
    13501 tcagccatag atatttcaac ttgcttattg gccatttaaa acacccattc cttttaatat
    13561 tttttcactt attaattcag catttttccc agacgggttt ccatctgata aatgtgtagc
    13621 aaaataatac ttatcatgat ttgtaattac gtaacctaca aaccacccat tattatactt
    13681 cccgtttact atacctgtac ctgttttccc atacagttca tacttttcat ttttcttaat
    13741 caataatgaa gaagataatt gattctttgc ttttttacta aaatggttat tttgttccat
    13801 catattttta aaaactatta cttgttcaag attagatatt ttcaaactat cttccatcca
    13861 atagctttta taacttccca aattttcatt accataattt aattgcttga gttgagccgc
    13921 agtatagttc tttggtattt gattactaat acgttcgaag taccaattaa ctgaattttg
    13981 cattgctgta tttaaatctt gttccttatt ccaagactcg aaaagataat gtttatgatt
    14041 ccatgacata cgtgaatttt tatcacttat aatatgacgg tcaagtccaa acagtgctaa
    14101 ataaattttg taagttgaat caggagaata tctttttcta ctttcttttt cattataaat
    14161 atagtatttg tctttcttca tgctgtacat aacgaaagat ccactatttg aaccaaaatt
    14221 tttactttca tctaaaattt ggtaatcgct ttgtaagggc tttttataat tataatcagt
    14281 taaggattgc cccattaaaa actggctttg aattatcatg ataaaaaaag taaaaataca
    14341 aataaaaatt agaattaatt ttgactgctt tttcagatcg gcttctttta tattaattaa
    14401 tcttcttttg agtaatgact ttttaccatt aaatgaatgg cttaatatat ttttattaaa
    14461 aaatggaaca tttaatacgg agtccataat agattccgca taagttttaa attcattttt
    14521 gttaatatta ttaaggacaa atctatcggc ttctacttca ttgtcatgaa ttatctttct
    14581 ttttacaata tgtactaatg gattgtaact cataataata gagaagatat taaagataat
    14641 taaatgtaaa gtatctctat ttttagcatg agcatattca tgcagtatta tatattttag
    14701 tcttttatca attacacttt taaaatatga actaggaatc aaaataatat atttcccata
    14761 ccaaaaagtt attggagatt gaatagcctc tgcttttcga atcacaatat tttttttata
    14821 ttgatggttg aaaagtatcg tatctatttt atttttttca ttttcgttta gataaagtga
    14881 ctgtttcttt aaatatttaa gatataataa ggctttcaaa aatttaaaac ttaaaataat
    14941 aactaaaact atccaaataa ctgtgcagat attatcaatt gaatcccaat taaacttatg
    15001 gatatctgtt gcgaactctt gaacaggttt ggtggtaatt atgttatggt tcaagtcgtg
    15061 tgacttactt tcaactgtgg gcgcttgatt attcacatta ttaaatttta taaaagagaa
    15121 tttaattggg ataaaaggaa ttaatccagc aagcacagtt agataccaaa ctttataatt
    15181 taaactataa ttaaaatagc gttttaatat gtacctaaaa aatactaaca atagaaatat
    15241 aaaacaaaag cttactacac tcattattag taatttagcc attttgacac cttctttcaa
    15301 atatttataa taaacaattg acatcaatat tacaattgta atattattgt tttgtaaaaa
    15361 ttacaactgt aatatcggag ggtttatttt gaaaaagtta atatttttaa ttgtaatggc
    15421 tttagtttta agtgcatgta attcaaacag ttcacatgcc aaagagttaa atgatttaga
    15481 aaaaaaatat aatgctcata ttggtgttta tgctttagat actaaaagtg gtaaggaagt
    15541 aaaatttaat tcagataaga gatttgccta tgcttcgact tcaaaagcga taaatagtgc
    15601 tattttgtta gaacaagtac cttataataa gttaaataaa aaagtacata ttaacaaaga
    15661 tgatatagtt gcttattctc ctattttaga aaaatatgta ggaaaagaca tcactttaaa
    15721 agaacttatt gaggcttcaa tgacatatag tgataataca gcaaacaata aaattataaa
    15781 agaaatcggt ggaatcaaaa aagttaaaca acgtctaaaa gaactaggag ataaagtaac
    15841 aaatccagtt agatatgaga tagaattaaa ttactattcg ccaaagagca aaaaagatac
    15901 ttcaacgcct gctgctttcg gcaagacttt aaataaactt atcgcaaatg gaaaattaag
    15961 caaaaaaaat aaaaatttct tacttgattt aatgtttaat aataaaaacg gagacacttt
    16021 aattaaagat ggtgttccaa aagactataa ggttgctgat aaaagtggtc aagcaataac
    16081 atatgcttct agaaatgatg ttgcttttgt ttatcctaag ggccaatctg aacctattgt
    16141 tttagtcatt tttacgaata aagacaataa aagtgataag ccaaatgata agttgataag
    16201 tgaaaccgcc aagagtgtaa tgaaggaatt ttaatattct aaatgcataa taaatactga
    16261 taacatctta tagtttgtat tatattttct attatcgttg acatgtataa ttttgatatc
    16321 aaaacctgat tttcccttta ttattttcga gatttatttt cttaattctc tttaacaaac
    16381 tagaaatatt gtatatacaa aaaatcataa ataatagatg aatagtttaa ttataggtgt
    16441 tcatcaatcg aaaaagcaac gtatcttatt taaagtgcgt tgcttttttc tcatttataa
    16501 ggttaaataa ttctcatata tcaagcaaag tgacataatt gttgaattta tagtaactga
    16561 aacgtatgat tagggtgtat attaattatg agatggaaat caatgattgt tggctatgcg
    16621 agagtatcat cgaacgatca aaatttagaa agacaacttg aaaatttaaa gacgttttgt
    16681 gctgaaaaaa tatttacaga aaaacagtct gggaaatcta ttgaaaatag accagtactt
    16741 caagaagcac ttaacttttt gaggatggga gatcggtttg tagtagaatc cattgattgt
    16801 ttaggtcgta attatgatga agtgattcat accgttaatt atttaaaaga caaagaagta
    16861 caattaatga ttactagctt acctatgatg aatgaagtgg ttggcaatcc attactggat
    16921 aagtttatga aagatttaat tattcaaata ttagcaatgg tttcagaaca agagagaaat
    16981 gaaagtaaac gtcgacaagc gcaaggaatt caagttgcga aggaaaaagg cgtatataaa
    17041 gggcgcccct tactttattc accaaatgct aaagatccac agaaacgtat tatttatcat
    17101 cgcgttgtag aaatgttaga agaaggccaa tcaattagta aaattgcgaa agaagtaaat
    17161 ataacaaggc agacgattta cagaattaaa aacgataatg atttgattta ataaactttg
    17221 tttcaatgca actgagagct tctcacagcg tctcaaaaca gatgattata atctattatg
    17281 agtttttaat aataagacaa gaaaagagag cgtaaatatg ctctctcttt ttctcattaa
    17341 cgaatgttta taacgcaatc atgatgagag tattaataca gttaattatt tgaaatactt
    17401 tagtttatat aatgttgaat tataggtagt gaaattgtat ttattataca ttgtcatatc
    17461 gttgtttaat gatagttaat ttaaggataa tagaattaat attatatata gatgaacaaa
    17521 acaagcaaca gagcagaaaa aacactttta gattattttt actcattctc tattttattt
    17581 atttttgcta taataaataa agaatattaa atgtaggtgt ttttatgaaa aagaaatttg
    17641 tttctagttg tattgctagt acaatcttat tcggcacttt attaggtgta acttataaag
    17701 ctgaagctgc aacagtacat gtagctggtg gtgtttggag ccatggtatt ggaaaacatt
    17761 acgtatggtc ttattatagt cacaataaaa gaaatcatgg ttcaacagca gtagggaaat
    17821 attcatcttt tagtggtgtt gctcgacctg gtgttcaatc taaggcatct gctccaaagg
    17881 cttggggtgg aaacaaaaca ttttatagtc ttcactaatt acatatatta attaaggaga
    17941 atagacagaa ttaagtaaac ttaattctgt ctattctctt gaaagaggca atatgaaaaa
    18001 attcaaatta tttttagatt ttagtacttt attattaatt tcagggctat tatttttatt
    18061 tttcttcaaa gaaaatgaag aaattatacc tgaaagttcc aatattttaa caatctctaa
    18121 ttgggataaa tctaacagta aatcaaaagt gttagatgtc attgaatcag gcgccaaaaa
    18181 tcaaaatata caaataatta aatccgttaa agattttgat aataaaaaag aattttttgt
    18241 tttcaactca aaacgaaata attctgactt tatacgtaat aaaacatcac ttttaactcc
    18301 atcagattta ttaaacagag agataaaagg aaagtattat attattggtg aacatttcaa
    18361 tgtagaagag cttacgagtg aattaaaaaa agctggttta acatctgaag ttgaatacat
    18421 aaatagaaac atattatttt ttgaattagt catagataat gatttattag tgcctttcat
    18481 attcttaggc gtattatatc ttttgtactt cttatatgac agaggatata atttgaaatt
    18541 ttatgctatt caaaagctac atggcttttc aactacacgc attatttttc ataatattca
    18601 tataaaaatc atttattggc tagtacttac cgctattttc tttattgcta atatattaat
    18661 cattcatata gccaatttag aattggattt cttaatgttt attcgtagat ttatcgtgtt
    18721 gctttttgtt tttgcttgta ttactacatt gctgtggctg atttcgtata gtcttctttt
    18781 gaagttaagt attccattaa tcttaaaagg gaaaaaagga tataagtttt caatatttat
    18841 gggtaccttc accaaatgta tcatggtgct aatactatct tttttactgg cacaaaattt
    18901 aaatgcttat acgaagttaa agaatatata tgactctgaa aaaatctggc aaaagttaga
    18961 taattactat acattagaga tttctcctaa tattagaaat tcagaagaaa aacaaatttt
    19021 agaaactaat atatacaatt taattaagaa aagcgaacaa cttggtggat tgcttttaaa
    19081 gaataataat atagccaatc ccgataaaaa caattacatt cctgaaaatg gcaatgtctt
    19141 ttttatcaat aacaattttc tgaatttcta taaaaatata aatcatgatt ttaaaatgat
    19201 tgacaatcat tcggataaaa taaacgtgtt tattcctcca aggttacaat atcaaaaatc
    19261 tgaaattcaa aaaaatcacc aaggatggat tgactttcaa aagcaacaaa acaaaaaagt
    19321 agatgtgcaa gtactgtcaa aaaacgtatc tgttttttct tttgatcgca caactaattt
    19381 gaaatttggg tatctagatt ctccaatagt aatgttgttg acacttgacg atttaacagg
    19441 agatttttat ttagctgctg tttctcaagg tggatatcta tttaaagatt tagatacact
    19501 taaacagttg cttaaagata atcacctaga agaagaaatt agcggtataa ctaattacaa
    19561 ggattctgtg ttaaatgaat taaatgaaac gaaaacaaaa atgataataa caatagttac
    19621 tattattatt aacgttttca ttcttttgat agctactgta tttgaaacaa ttcaatattt
    19681 tagctggaat aaaaagcaac tattattaag aaaaattcat ggttattcat tattcagcag
    19741 taatgtacgt tatttaacaa tttctatctt actttctatt atgttagctt acactacgca
    19801 tattttattt ggttcaaaga tattactatt cataataatg tctattgcta ttattcaaca
    19861 tttacttcaa attgcttata ttaaatatct tgaaaaatac tttaaagatt taatgaggga
    19921 gatttaaaca atgaaaagaa ctttaattat tgtaacaatt gtactattaa tcatcatact
    19981 tagtctgtta ttggttagaa atgagcattt agatcgtttt aacccactgt taaaagaaaa
    20041 agtatcttat gccaaagttc caaaagatac ccaggactat agaaatataa ctgtatactc
    20101 taaaaatgga gaaaaaaaga gttataaatt ggatttttta ggttatgatc ctacaaaaga
    20161 atatgtgaaa gtaaatcata aagggaaata tgtgcgttcg atagaataca ttacaaaaga
    20221 tattcctagc tttttaaaat gaggtgaccg atagtgataa aacttgaaaa tgtttttgta
    20281 aaaaaaggta ataaaaacat tttagacgga tgtaacttta attttgaaaa aggaaaatca
    20341 tatgctttag ttggagaaag tggcgctgga aaatctactt tacttaacat aatcgctggg
    20401 ttcgaagatg tatcacaagg aagcatatat attgaagata agttactaaa aaagaaagtc
    20461 gatttttata gatatacgtt agggtatttg tttcaaaatt ttgctttact tgaaaatcaa
    20521 acaatcagtc aaaatttaga tttagcccta aagttcaaaa agaataaaaa agataatatg
    20581 aacttaaaga aagaagtatt aaaaaaggtc ggcctagatt tagatatcaa gagaattgtt
    20641 agttctctaa gcggtggtga acaacaaaga gtagcattgg caagattaat attaaaagat
    20701 ccgaaaatca ttttagctga tgaa
//
