LOCUS       NZ_CP120010            20707 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Staphylococcus aureus strain Dog158 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP120010
VERSION     NZ_CP120010.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33696834
            Assembly: GCF_034042995.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20707)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Canine Staphylococcaceae circulating in a Kenyan animal shelter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20707)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
  REMARK    Annotation added by database at submitter's request
REFERENCE   3  (bases 1 to 20707)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Flye v. v2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 345x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/06/2024 11:11:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,733
            CDSs (total)                      :: 2,650
            Genes (coding)                    :: 2,583
            CDSs (with protein)               :: 2,583
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 33 of 67
            Pseudo Genes (incomplete)         :: 33 of 67
            Pseudo Genes (internal stop)      :: 20 of 67
            Pseudo Genes (multiple problems)  :: 18 of 67
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20707
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Dog158"
                     /isolation_source="nasal swab"
                     /host="Canis lupus familiaris"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya:Nairobi"
                     /lat_lon="1.3345 S 36.7331 E"
                     /collection_date="2015-06-27"
                     /collected_by="Joerg Jores, Anna Lacasta, Anne Liljander,
                     Paul Ssajjakambwe (International Livestock Research
                     Institute, ILRI)"
     gene            complement(200..745)
                     /locus_tag="P3U45_RS13550"
                     /old_locus_tag="P3U45_13550"
     CDS             complement(200..745)
                     /locus_tag="P3U45_RS13550"
                     /old_locus_tag="P3U45_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(839..1468)
                     /gene="mobV"
                     /locus_tag="P3U45_RS13555"
                     /old_locus_tag="P3U45_13555"
                     /pseudo=""
     CDS             complement(839..1468)
                     /gene="mobV"
                     /locus_tag="P3U45_RS13555"
                     /old_locus_tag="P3U45_13555"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(1706..2332)
                     /locus_tag="P3U45_RS13560"
                     /old_locus_tag="P3U45_13560"
     CDS             complement(1706..2332)
                     /locus_tag="P3U45_RS13560"
                     /old_locus_tag="P3U45_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(2344..2655)
                     /locus_tag="P3U45_RS13565"
                     /old_locus_tag="P3U45_13565"
     CDS             complement(2344..2655)
                     /locus_tag="P3U45_RS13565"
                     /old_locus_tag="P3U45_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(2659..4593)
                     /locus_tag="P3U45_RS13570"
                     /old_locus_tag="P3U45_13570"
     CDS             complement(2659..4593)
                     /locus_tag="P3U45_RS13570"
                     /old_locus_tag="P3U45_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(4668..4961)
                     /locus_tag="P3U45_RS13575"
                     /old_locus_tag="P3U45_13575"
     CDS             complement(4668..4961)
                     /locus_tag="P3U45_RS13575"
                     /old_locus_tag="P3U45_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(5375..5983)
                     /locus_tag="P3U45_RS13580"
                     /old_locus_tag="P3U45_13580"
     CDS             complement(5375..5983)
                     /locus_tag="P3U45_RS13580"
                     /old_locus_tag="P3U45_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(6352..7197)
                     /gene="blaZ"
                     /locus_tag="P3U45_RS13585"
                     /old_locus_tag="P3U45_13585"
     ARG             complement(6356..7197)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            7304..9061
                     /gene="blaR1"
                     /locus_tag="P3U45_RS13590"
                     /old_locus_tag="P3U45_13590"
     ARG             7305..9058
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="96.07"
                     /coverage="100.0"
     gene            9051..9431
                     /gene="blaI"
                     /locus_tag="P3U45_RS13595"
                     /old_locus_tag="P3U45_13595"
     ARG             9052..9428
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            9695..10288
                     /locus_tag="P3U45_RS13600"
                     /old_locus_tag="P3U45_13600"
     CDS             9695..10288
                     /locus_tag="P3U45_RS13600"
                     /old_locus_tag="P3U45_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_054192780.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERSVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKKDEKQGEVSN"
                     /name="recombinase family protein"
     gene            10260..11702
                     /locus_tag="P3U45_RS13605"
                     /old_locus_tag="P3U45_13605"
     CDS             10260..11702
                     /locus_tag="P3U45_RS13605"
                     /old_locus_tag="P3U45_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_054192781.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISESKGI
                     ALSTLYRWNKSYKEQGLKGLIYATRADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     ITNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDLQHARSQRRKHLKQNIASPSTTELIKKEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            11695..12510
                     /locus_tag="P3U45_RS13610"
                     /old_locus_tag="P3U45_13610"
     CDS             11695..12510
                     /locus_tag="P3U45_RS13610"
                     /old_locus_tag="P3U45_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(12630..13604)
                     /locus_tag="P3U45_RS13615"
                     /old_locus_tag="P3U45_13615"
     CDS             complement(12630..13604)
                     /locus_tag="P3U45_RS13615"
                     /old_locus_tag="P3U45_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_054192782.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKNLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(13816..13908)
                     /locus_tag="P3U45_RS13620"
                     /old_locus_tag="P3U45_13620"
     CDS             complement(13816..13908)
                     /locus_tag="P3U45_RS13620"
                     /old_locus_tag="P3U45_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(14077..14424)
                     /locus_tag="P3U45_RS13625"
                     /old_locus_tag="P3U45_13625"
     CDS             complement(14077..14424)
                     /locus_tag="P3U45_RS13625"
                     /old_locus_tag="P3U45_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(14443..15060)
                     /gene="cadD"
                     /locus_tag="P3U45_RS13630"
                     /old_locus_tag="P3U45_13630"
     ARG             complement(14447..15060)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            complement(16271..>16553)
                     /locus_tag="P3U45_RS13635"
                     /old_locus_tag="P3U45_13635"
                     /pseudo=""
     CDS             complement(16271..>16553)
                     /locus_tag="P3U45_RS13635"
                     /old_locus_tag="P3U45_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(16564..17240)
                     /locus_tag="P3U45_RS13640"
                     /old_locus_tag="P3U45_13640"
                     /pseudo=""
     CDS             complement(16564..17240)
                     /locus_tag="P3U45_RS13640"
                     /old_locus_tag="P3U45_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            17651..18394
                     /locus_tag="P3U45_RS13645"
                     /old_locus_tag="P3U45_13645"
     CDS             17651..18394
                     /locus_tag="P3U45_RS13645"
                     /old_locus_tag="P3U45_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(18613..18798)
                     /locus_tag="P3U45_RS13650"
                     /old_locus_tag="P3U45_13650"
     CDS             complement(18613..18798)
                     /locus_tag="P3U45_RS13650"
                     /old_locus_tag="P3U45_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            18947..19018
                     /locus_tag="P3U45_RS13655"
                     /old_locus_tag="P3U45_13655"
     CDS             18947..19018
                     /locus_tag="P3U45_RS13655"
                     /old_locus_tag="P3U45_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(19257..19598)
                     /locus_tag="P3U45_RS13660"
                     /old_locus_tag="P3U45_13660"
     CDS             complement(19257..19598)
                     /locus_tag="P3U45_RS13660"
                     /old_locus_tag="P3U45_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19685..20545)
                     /locus_tag="P3U45_RS13665"
                     /old_locus_tag="P3U45_13665"
     CDS             complement(19685..20545)
                     /locus_tag="P3U45_RS13665"
                     /old_locus_tag="P3U45_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     ARG             complement(6353..7197)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             1..9961
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(16067..16214)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17652..18394
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19686..20545)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(1194..1468)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 atgtggcaaa aacactcctt ttatgtggca aaaacactcc tttaggcatt gaaatccctt
       61 gttgctctag ggctgaacaa gcccctaaaa aggtttttaa aaagatttat aaaaatatat
      121 taaaaagttc gaggggggct acctattttt catcctaaaa aataattaac ctcaaacaaa
      181 tgcatttaaa tatctatttt tataatgtat aaccatcttc tctatcttct ttaaaaatga
      241 tttctcgttc ttgtgcttga tatttcttct taaagaactg ttcatcattg ttatctatcg
      301 tcattacttc acgtatttta gaattgtcta aatgattatc aatatgattt attagtgtat
      361 gataacgctc ttctttcatc atacttttaa tgattttaaa aacttgattg aataacttaa
      421 gcgtataatt tagttcttta tctttctttt cattctctga caacaaataa ttataacgtt
      481 gtgctaaatc attaaattct tcaaccagct tttcattttc catatggaca ctagtcaatt
      541 cattaactaa actttcattt tgtttctctg ctttttttaa tgacttccca cttttaatac
      601 attcataatc atctaatatc atctgtgctg ctttaatttg tttagtgtat ttttcaaaat
      661 cagttttagt aattacaata ttgcctgttt cttgcttctc tttatgaaac catccaccta
      721 catttttagt tttaatttca tacatgacac tcagaagctt tttaagcgta tctaatgatt
      781 tttggtagtt ttgtatcaat ttatcatttt cttgctttaa ataatcctct atttgcttct
      841 agcgcatatg catttgttta tgatattctg ttttttgttt ataacggcta acttgatcat
      901 gtttttcttt tgtaagttgt ctagaaattc ctcgttttaa atcatagcct tgcttattaa
      961 tatacgtatt gaatctatct tggaattcgg ttaatgcttt tttattacct acaacttctt
     1021 tcgcacttaa acgtccatct ttagtaatag gaactacgcc ataatgcata tgtggtgtta
     1081 tctcatccat atgtactgtc gcatataaaa gattttcttt accgtattct tcttccaaga
     1141 acgctttagc atgcttaaaa aactattttg tctcttcttc agataattga ttaaaaaaca
     1201 cattatctga tgtaattaat ccatcaatat gtttaatggc atctgttcta attttgcgtt
     1261 tccctttata atttttttcg attttctcat caattttttt attaaaatca aacttagtat
     1321 cattgactaa atcatagttt aaatatgact tacttaaatc aatatctata ttttcataat
     1381 ttttattttc tctttgaata tgtctttgaa tacctcttgt atttgttttt gatttcactt
     1441 taacaactcg aataattgaa taagacataa taaatcaact tccactgcat atgattataa
     1501 cacctaaaca cagaaaagtt ttaacatact agacttatta aaaaccaaat aagtcattaa
     1561 aaacgtgtgc tctgcgaggc ttgttttttg tcatcataaa aaaggactgg aaaatccagt
     1621 ccttaaatta aaaaactcaa aagtaatgac taatcatatt tcatattgtt ttttctctat
     1681 gtatggctat acctatcaat atttcttaac ttctaagctc agaaatattg actatgacat
     1741 caaatcgttt cgcaagctct aaatcatgcg ttacgacaat catagtttta ttttcatcaa
     1801 gtagcttcaa taataaatca ataactattt ttccattttt cgtatctagt gacccagtag
     1861 gttcatcagc taaaatgatt ttcggatctt ttaatattaa tcttgccaat gctactcttt
     1921 gttgttcacc accgcttaga gaactaacaa ttcttttgat atctaaatct aggccgacct
     1981 tttttaatac ttctttcttt aagttcatat tatctttttt attctttttg aactttaggg
     2041 ctaaatctaa attttgactg attgtttgat tttcaagtaa agcaaaattt tgaaacaaat
     2101 accctaacgt atatctataa aaatcgactt tcttttttag taacttatct tcaatatata
     2161 tgcttccttg tgatacatct tcgaacccag cgattatgtt aagtaaagta gattttccag
     2221 cgccactttc tccaactaaa gcatatgatt ttcctttttc aaaattaaag ttacatccgt
     2281 ctaaaatgtt tttattacct ttttttacaa aaacattttc aagttttatc actatcggtc
     2341 acctcatttt aaaaagctag gaatatcttt tgtaatgtat tctatcgaac gcacatattt
     2401 ccctttatga tttactttca catattcttt tgtaggatca taacctaaaa aatccaattt
     2461 ataactcttt ttttctccat ttttagagta tacagttata tttctatagt cctgggtatc
     2521 ttttggaact ttggcataag atactttttc ttttaacagt gggttaaaac gatctaaatg
     2581 ctcatttcta accaataaca gactaagtat gatgattaat agtacaattg ttacaataat
     2641 taaagttctt ttcattgttt aaatctccct cattaaatct ttaaagtatt tttcaagata
     2701 tttaatataa gcaatttgaa gtaaatgttg aataatagca atagacatta ttatgaatag
     2761 taatatcttt gaaccaaata aaatatgcgt agtgtaagct aacataatag aaagtaagat
     2821 agaaattgtt aaataacgta cattactgct gaataatgaa taaccatgaa tttttcttaa
     2881 taatagttgc tttttattcc agctaaaata ttgaattgtt tcaaatacag tagctatcaa
     2941 aagaatgaaa acgttaataa taatagtaac tattgttatt atcatttttg ttttcgtttc
     3001 atttaattca tttaacacag aatccttgta attagttata ccgctaattt cttcttctag
     3061 gtgattatct ttaagcaact gtttaagtgt atctaaatct ttaaatagat atccaccttg
     3121 agaaacagca gctaaataaa aatctcctgt taaatcgtca agtgtcaaca acattactat
     3181 tggagaatct agatacccaa atttcaaatt agttgtgcga tcaaaagaaa aaacagatac
     3241 gttttttgac agtacttgca catctacttt tttgttttgt tgcttttgaa agtcaatcca
     3301 tccttggtga tttttttgaa tttcagattt ttgatattgt aaccttggag gaataaacac
     3361 gtttatttta tccgaatgat tgtcaatcat tttaaaatca tgatttatat ttttatagaa
     3421 attcagaaaa ttgttattga taaaaaagac attgccattt tcaggaatgt aattgttttt
     3481 atcgggattg gctatattat tattctttaa aagcaatcca ccaagttgtt cgcttttctt
     3541 aattaaattg tatatattag tttctaaaat ttgtttttct tctgaatttc taatattagg
     3601 agaaatctct aatgtatagt aattatctaa cttttgccag attttttcag agtcatatat
     3661 attctttaac ttcgtataag catttaaatt ttgtgccagt aaaaaagata gtattagcac
     3721 catgatacat ttggtgaagg tacccataaa tattgaaaac ttatatcctt ttttcccttt
     3781 taagattaat ggaatactta acttcaaaag aagactatac gaaatcagcc acagcaatgt
     3841 agtaatacaa gcaaaaacaa aaagcaacac gataaatcta cgaataaaca ttaagaaatc
     3901 caattctaaa ttggctatat gaatgattaa tatattagca ataaagaaaa tagcggtaag
     3961 tactagccaa taaatgattt ttatatgaat attatgaaaa ataatgcgtg tagttgaaaa
     4021 gccatgtagc ttttgaatag cataaaattt caaattatat cctctgtcat ataagaagta
     4081 caaaagatat aatacgccta agaatatgaa aggcactaat aaatcattat ctatgactaa
     4141 ttcaaaaaat aatatgtttc tatttatgta ttcaacttca gatgttaaac cagctttttt
     4201 taattcactc gtaagctctt ctacattgaa atgttcacca ataatataat actttccttt
     4261 tatctctctg tttaataaat ctgatggagt taaaagtgat gttttattac gtataaagtc
     4321 agaattattt cgttttgagt tgaaaacaaa aaattctttt ttattatcaa aatctttaac
     4381 ggatttaatt atttgtatat tttgattttt ggcgcctgat tcaatgacat ctaacacttt
     4441 tgatttactg ttagatttat cccaattaga gattgttaaa atattggaac tttcaggtat
     4501 aatttcttca ttttctttga agaaaaataa aaataatagc cctgaaatta ataataaagt
     4561 actaaaatct aaaaataatt tgaatttttt catattgcct ctttcaagag aatagacaga
     4621 attaagttta cttaattctg tctattctcc ttaattaata tatgtaatta gtgaagacta
     4681 taaaatgttt tgtttccacc ccaagccttt ggagcagatg ccttagattg aacaccaggt
     4741 cgagcaacac cactaaaaga tgaatatttc cctactgctg ttgaaccatg atttctttta
     4801 ttgtgactat aataagacca tacgtaatgt tttccaatac catggctcca aacaccacca
     4861 gctacatgta ctgttgcagc ttcagcttta taagttacac ctaataaagt gccgaataag
     4921 attgtactag caatacaact agaaacaaat ttctttttca taaaaacacc tacatttaat
     4981 attctttatt tattatagca aaaataaata aaatagagaa tgagtaaaaa taatctaaaa
     5041 gtgttttttc tgctctgttg cttgttttgt tcatctatat ataatattaa ttctattatc
     5101 cttaaattaa ctatcattaa acaacgatat gacaatgtat aataaataca atttcactac
     5161 ctataattca acattatata aactaaagta tttcaaataa ttaactgtat taatactctc
     5221 atcatgattg cgttataaac attcgttaat gagaaaaaga gagagcatat ttacgctctc
     5281 ttttcttgtc ttattattaa aaactcataa tagattataa tcatctgttt tgagacgctg
     5341 tgagaagctc tcagttgcat tgaaacaaag tttattaaat caaatcatta tcgtttttaa
     5401 ttctgtaaat cgtctgcctt gttatattta cttctttcgc aattttacta attgattggc
     5461 cttcttctaa catttctaca acgcgatgat aaataatacg tttctgtgga tctttagcat
     5521 ttggtgaata aagtaagggg cgccctttat atacgccttt ttccttcgca acttgaattc
     5581 cttgcgcttg tcgacgttta ctttcatttc tctcttgttc tgaaaccatt gctaatattt
     5641 gaataattaa atctttcata aacttatcca gtaatggatt gccaaccact tcattcatca
     5701 taggtaagct agtaatcatt aattgtactt ctttgtcttt taaataatta acggtatgaa
     5761 tcacttcatc ataattacga cctaaacaat caatggattc tactacaaac cgatctccca
     5821 tcctcaaaaa gttaagtgct tcttgaagta ctggtctatt ttcaatagat ttcccagact
     5881 gtttttctgt aaatattttt tcagcacaaa acgtctttaa attttcaagt tgtctttcta
     5941 aattttgatc gttcgatgat actctcgcat agccaacaat cattgatttc catctcataa
     6001 ttaatataca ccctaatcat acgtttcagt tactataaat tcaacaatta tgtcactttg
     6061 cttgatatat gagaattatt taaccttata aatgagaaaa aagcaacgca ctttaaataa
     6121 gatacgttgc tttttcgatt gatgaacacc tataattaaa ctattcatct attatttatg
     6181 attttttgta tatacaatat ttctagtttg ttaaagagaa ttaagaaaat aaatctcgaa
     6241 aataataaag ggaaaatcag gttttgatat caaaattata catgtcaacg ataatagaaa
     6301 atataataca aactataaga tgttatcagt atttattatg catttagaat attaaaattc
     6361 cttcattaca ctcttggcgg tttcacttat caacttatca tttggcttat cacttttatt
     6421 gtctttattc gtaaaaatga ctaaaacaat aggttcagat tggcccttag gataaacaaa
     6481 agcaacatca tttctagaag catatgttat tgcttgacca cttttatcag caaccttata
     6541 gtcttttgga acaccatctt taattaaagt gtctccgttt ttattattaa acattaaatc
     6601 aagtaagaaa tttttatttt ttttgcttaa ttttccattt gcgataagtt tatttaaagt
     6661 cttgccgaaa gcagcaggcg ttgaagtatc ttttttgctc tttggcgaat agtaatttaa
     6721 ttctatctca tatctaactg gatttgttac tttatctcct agttctttta gacgttgttt
     6781 aacttttttg attccaccga tttcttttat aattttattg tttgctgtat tatcactata
     6841 tgtcattgaa gcctcaataa gttcttttaa agtgatgtct tttcctacat atttttctaa
     6901 aataggagaa taagcaacta tatcatcttt gttaatatgt acttttttat ttaacttatt
     6961 ataaggtact tgttctaaca aaatagcact atttatcgct tttgaagtcg aagcataggc
     7021 aaatctctta tctgaattaa attttacttc cttaccactt ttagtatcta aagcataaac
     7081 accaatatga gcattatatt ttttttctaa atcatttaac tctttggcat gtgaactgtt
     7141 tgaattacat gcacttaaaa ctaaagccat tacaattaaa aatattaact ttttcaaaat
     7201 aaaccctccg atattacagt tgtaattttt acaaaacaat aatattacaa ttgtaatatt
     7261 gatgtcaatt gtttattata aatatttgaa agaaggtgtc aaaatggcta aattactaat
     7321 aatgagtgta gtaagctttt gttttatatt tctattgtta gtatttttta ggtacatatt
     7381 aaaacgctat tttaattata gtttaaatta taaagtttgg tatctaactg tgcttgctgg
     7441 attaattcct tttatcccaa ttaaattctc ttttataaaa tttaataatg tgaataatca
     7501 agcgcccaca gttgaaagta agtcacacga cttgaaccat aacataatta ccaccaaacc
     7561 tgttcaagag ttcgcaacag atatccataa gtttaattgg gattcaattg ataatatctg
     7621 cacagttatt tggatagttt tagttattat tttaagtttt aaatttttga aagccttatt
     7681 atatcttaaa tatttaaaga aacagtcact ttatctaaac gaaaatgaaa aaaataaaat
     7741 agatacgata cttttcaacc atcaatataa aaaaaatatt gtgattcgaa aagcagaggc
     7801 tattcaatct ccaataactt tttggtatgg gaaatatatt attttgattc ctagttcata
     7861 ttttaaaagt gtaattgata aaagactaaa atatataata ctgcatgaat atgctcatgc
     7921 taaaaataga gatactttac atttaattat ctttaatatc ttctctatta ttatgagtta
     7981 caatccatta gtacatattg taaaaagaaa gataattcat gacaatgaag tagaagccga
     8041 tagatttgtc cttaataata ttaacaaaaa tgaatttaaa acttatgcgg aatctattat
     8101 ggactccgta ttaaatgttc cattttttaa taaaaatata ttaagccatt catttaatgg
     8161 taaaaagtca ttactcaaaa gaagattaat taatataaaa gaagccgatc tgaaaaagca
     8221 gtcaaaatta attctaattt ttatttgtat ttttactttt tttatcatga taattcaaag
     8281 ccagttttta atggggcaat ccttaactga ttataattat aaaaagccct tacaaagcga
     8341 ttaccaaatt ttagatgaaa gtaaaaattt tggttcaaat agtggatctt tcgttatgta
     8401 cagcatgaag aaagacaaat actatattta taatgaaaaa gaaagtagaa aaagatattc
     8461 tcctgattca acttacaaaa tttatttagc actgtttgga cttgaccgtc atattataag
     8521 tgataaaaat tcacgtatgt catggaatca taaacattat cttttcgagt cttggaataa
     8581 ggaacaagat ttaaatacag caatgcaaaa ttcagttaat tggtacttcg aacgtattag
     8641 taatcaaata ccaaagaact atactgcggc tcaactcaag caattaaatt atggtaatga
     8701 aaatttggga agttataaaa gctattggat ggaagatagt ttgaaaatat ctaatcttga
     8761 acaagtaata gtttttaaaa atatgatgga acaaaataac cattttagta aaaaagcaaa
     8821 gaatcaatta tcttcttcat tattgattaa gaaaaatgaa aagtatgaac tgtatgggaa
     8881 aacaggtaca ggtatagtaa acgggaagta taataatggg tggtttgtag gttacgtaat
     8941 tacaaatcat gataagtatt attttgctac acatttatca gatggaaacc cgtctgggaa
     9001 aaatgctgaa ttaataagtg aaaaaatatt aaaaggaatg ggtgttttaa atggccaata
     9061 agcaagttga aatatctatg gctgaatggg atgttatgaa tataatatgg gataaaaaat
     9121 cagtatcagc taatgaaatt gtagttgaaa ttcaaaaata taaagaagtt agtgataaaa
     9181 cgattagaac attaatcaca agactatata aaaaagagat tataaaacga tacaaatcag
     9241 aaaatattta tttttactca tcaaatatta aagaagacga tattaaaatg aaaactgcta
     9301 aaacctttct taataaactg tatggagggg atatgaaaag tttagtgttg aattttgcga
     9361 aaaatgaaga attaaataac aaagaaattg aagaattgcg agatatttta aatgatatta
     9421 gtaaaaagta attagaggta tgtttcaaac ataatacata tgtaaactat gcttgactct
     9481 tattaaatta gttttgttaa tgacatttaa aatatattat taaagatgag agtgtacaga
     9541 aaataaccat tttctgtaca ctcttctttt atgtctaaat aagtaagaat tacataggat
     9601 tatgtgttca aaaacccaat aaaaaatcta tgttcataaa aggccttgta attaagttat
     9661 ggtacactga agatgtatat aggaggtttg tattttgaaa ataggttatg caagagtttc
     9721 aactggatta caaaatttaa atttacagga ggatcgatta aatacatatg gttgtgaaaa
     9781 gatatttaat gaccatatga gtggttcaaa aagtaaaaga cctggtttag ataaagcaat
     9841 tgaatttgcg aggtcaggag atacgattgt tgtttggaga ttagatagat tgggacgtaa
     9901 tatggaagat ttaatcacat tagttaatga acttaatgag agaagcgtga gtttccatag
     9961 cttagaagaa aatataacca tggataaatc aagttctaca ggacaattat tatttcattt
    10021 attcgcagca tttgcagagt ttgaacggaa tttaatttta gaacgttctt cagctggcag
    10081 aattgcagca cgtgctagag gccgatatgg aggcagacca gaaaaattaa atcaaaaaga
    10141 tttaaactta cttaagacac tttatgataa tggcacgcca atcaagacaa ttgcagaaca
    10201 gtggcatgtt tcacgtacaa caatttatcg ttacctcaat aaattggagg acaagaaaga
    10261 tgaaaaacaa ggagaagtat ctaactaatt tttctgaagc caaacgtaaa aaagctactc
    10321 aaaagtacaa tattataaaa ccttttatcc taggcgaaca atctttatca agtatttctg
    10381 aaagtaaagg gattgcgtta agcacccttt ataggtggaa taagtcatat aaagaacaag
    10441 gacttaaagg gctaatctat gcgacaagag ctgataaagg aacacgtaaa atagaaccaa
    10501 agataattga tgaaattgaa cgccttgcgc ttatgaataa aagaaatagt atagccacaa
    10561 ttcataggaa aatcactaat tactgtaaag aaaataattt tgatatacca agttataaac
    10621 aaatttatag tgttattaaa gcgatgccta agtctgttat tgatttctct catcagggtg
    10681 aaaaatacta tcaaaataag tacgatttaa tacaaattag agaatcctcg agacccaatg
    10741 aaatatggca agcagaccat actttgctag atatctttat attagaccaa aaaggtaata
    10801 tcaatagacc atggctaact attattatgg atgactatag tcgtgcaatt gcaggctatt
    10861 tcttaagttt tgatgccccc aatgctcaaa acacagcatt aacactacac caagcaatat
    10921 ggaataaaaa tgataccaat tggccagtgt gtggtatacc cgaaaaattc tacacagatc
    10981 atggaagtga ctttacttca catcatatgg aacaagtcgc tattgatttg aaaattaact
    11041 tgatgttttc gaaagttggt gttcctcgtg gtcgtggaaa aatagaacga ttctttcaga
    11101 cagttaatca aactttctta gaacaactgc ctggatatat aaacaataat gatactccta
    11161 gtaatctaat aaattttcac aattttgaag aaaaattacg ttacttttta attgaagatt
    11221 ataatcaaaa agaacatagt actatccata ccacgcctat cagtcgttgg aatagtaatc
    11281 actttttccc taatatgcca agtagcttag aacaacttga tttattattg ttggaaatac
    11341 ctaaatctag aaaagttcat tcagatggca ttcattttca aggttttcga tacagtaata
    11401 ctaatctagc agcttatgta ggtgaatatg tactgattcg ttataaccca aatgatatgg
    11461 ctgaaatacg tgtgttttat agagatgaat ttctttgtac tgctatatgt ccagaaatag
    11521 ctgattactc catagatata aaagacttac agcacgctcg tagtcagaga agaaaacact
    11581 taaaacaaaa tattgctagt ccaagtacca cggaattaat taagaaagaa aaaaattgtg
    11641 gttattcacc tcaagaaacg actaaaaacg tcaaaaaatt aaagaggtat cgtaatgact
    11701 aaaaatcaaa attttattga aacgaaagag tataaacgct ttgctgaatt ttgtgatgct
    11761 tgtattaaat atcagtatat tggtatatgt tatggtcaac ctggtgtcgg aaaaacttta
    11821 tcgtctaggt attacacaaa ttgggatact attgaaaaac aagttaacca tagaggttgg
    11881 gaagatttag ctagtaaaac gaccgatgac atactatcgg tggataaaat attttataat
    11941 gcaccagcag aaaaacaaac taaattaagg aatgatttat atagtattac tgcaatcatt
    12001 gatttgggtc aaaaattaca tgttgtaaat aagtatggac atgaacatag taaacattat
    12061 agtgatatgt ttaaatatat tgatttaatt atagtagatg agattgatcg ccttaaagtg
    12121 caacatttag agcaattaag agctatttat gatgaacata atttagcaat gatatttatt
    12181 ggtatgccgg gtatagagaa aaaactatct cgttatcctc aactatattc gcgtataggt
    12241 tttgcgcatg aatttgataa tctaagtaaa gatgagacgc atcatatatt agaatataag
    12301 tggcaagact taggatttga tttaaaactc gaagacttta ctgattatga ggcaataacg
    12361 acgattatta aaattacaaa agggaatttt aggctgattc atcgtttatt tgcgcagata
    12421 gacagaatta tggatataaa tggtttagat aaaataagta cagaagttgt agaaacagct
    12481 agagatagtt tagttatagg tattcgataa tagaaaaagc aacgcatttt aatatagtgc
    12541 gttgcttttc tcatttatta ggtaaagtca ttctcatata tcgagtaaag tgacaacaat
    12601 tatatatgta tgattagggt gtacttatat cattcatata aatgtttatt tataccctca
    12661 ataaaaatat tatatgcttt taagcaccta tcacattcct tataaaaatg tttattcaat
    12721 cctttaatat cgactagcgt agtcttataa tttttttgta acaattttaa atcctcttcg
    12781 taaaagctta atttaaaatg accggcttga gctaatggct tttttccttg tttaattaaa
    12841 atcaatatgt tttttaaatg ttttaaaaag tttttataat cataaacttt tattttcatg
    12901 aatgatttat gtggattatt ttcataattt agcaggtagt tttctatatc ttcaatataa
    12961 ctatcatcaa atggtgtgtg ctggaaataa aaagttttta catacatgaa tattttataa
    13021 agttcttctt tcaaaaaatc atatgtatct aaatctcttt gtatagcatc caattttttt
    13081 aaatttttta catttttacc acaatcctgt actcttatcc atccactatt ttctttaatt
    13141 tcactaggta cactttgcat taaagtctga gatactttac tttttaattc cgaaatatca
    13201 ttaatatttg gactaattag tctattttct ttaacttttg tcttaaactc atctaatttt
    13261 ttagactttt ccgcggattc ggtagatgct ttattcatct caaaaacata tataggttta
    13321 cctaaagatt tagcaaaatt gtactccatt tctgtatagc taatattttc ttcactatca
    13381 attgttccat aactagaacc taacaataat atcactgcat ctgattcatt gatccattgt
    13441 gttattattt cccattggct tttactactt gagttaaaaa gttccatacc tgctggaata
    13501 ttattactgt ttaaaactgc ttctactact gcttgacgct cttctattaa atctaaataa
    13561 gttgatgaaa taaaaatttg atatttaatt ttagtattac tcatatatgc tcctttaata
    13621 aaaaatcaat ttacataaat atatcatatg ataatatcca aaaagactac ttaaaatatt
    13681 atctttttgc attcctctac taaccagtgt tataatctag ataacgaaaa tgattaacaa
    13741 ttaatgcacc aatccccaca ctactgcaat agtgtgggga ttttttcgat gctggcttat
    13801 aaagtcgcct attaattatt tgttgcgttt actaagccaa taagtataat acgcaacagc
    13861 acagccactg atgactggtg ctatgatgtg aacgaaaatg attagcaaag taatgcacct
    13921 cctctctgcg tctgaattga cgcctgagag ataggcgacc tgtatattat atcatctccg
    13981 aatatacgat gatagataac ttccgataag tcgtcttatg ttatataact ttgtttttta
    14041 tagtatcaag acaagaagaa actcgtttca ctcgtttcaa aaaccctcct gatttttaga
    14101 gaaaaactct cttatttcat cgtctttaat aaaataatat gccatctttc catctttata
    14161 aaaatcaagt acctcatttt tatataaaag ccttaaatga tgtgaagttg aagcaacact
    14221 cattttcaat atcaaagaaa tatcacaaac acacaactca tcttctttaa tcaaagataa
    14281 tatgattttc aatttcttct catcacaaat tttttctaaa atgttaagta atttcttaga
    14341 tttatcatct tctaaaaaac ttaaagcatt gttaacttta tcctcatgta cacagatcac
    14401 atcacaagta ttttcataac tcatataaaa tcacacccta aattaaaata taaatcctaa
    14461 aattgtttga atagtgtcat tttcaataat aataaataaa cctaaagcta tataaatgat
    14521 agccataatc caacgactaa atttctcaac aatttctcca attcctggga tattagctaa
    14581 tttttgtgca gtaaacacca agaagaaaat taaaattaaa aagacaaaca gagtaagtaa
    14641 taaattagta acacttaatg tcacaaaata cggaacaaat aaaccaatat tatcggcgcc
    14701 acaacttgct atcgtaacaa ttgcaaccgt accaactaat ttagacaatc ctttttcatt
    14761 caattctttt ttagctctct tttctccttc acaatcatca taaatagcca ctttaattcc
    14821 aagataaatt ggtattaaac ccaataaacc taatatccac ttttctggaa cataatttaa
    14881 tacaaaagct aaaaacaaac taactaatat taaaataata gaccctaaat attgaccaac
    14941 ataaatattt ctatattctt ttctagtctt tgctctagca aaaaatatta ataaaattac
    15001 taataaatca actgctgtag caatataaag aacagcagca gcaacaaccg tttgaatcat
    15061 aatacacctc attcaaaaat atttttgaat gtattataac ttatattttt aaataatcat
    15121 aggtgcttta ttccaattgc tttattgacg ttgagcctcg gaacccttaa caatcccaaa
    15181 acttgtcgaa tggtcggctt aatagctcac gctatgccga cattcgtctg caagtttagt
    15241 taagggttct tctcaacgca caataaattt tctcggcata aatgcgtgtc tatgcgtaga
    15301 catggagaca cttcagaatt atggagtgat tacatgagtt taactatttt tctttattca
    15361 gttttaggaa gtttattagc aaattatatc tacgaaaaat cttcaaaata aataactttt
    15421 tcggttctac tttgtacact ttatctacct ggtagaccta attgttattg ctttacaggt
    15481 ctaaaattcg tcgttataat ctagttaaat cccgtaaggg cgcacttata cgtcggataa
    15541 atcgacatgt gcaaaaacgt aatcgacctt cgtcgatttt tttatttcaa aattaaagaa
    15601 acggcttgag atattccgag cagttataaa aattaatttg cgttgaatat tgctactaca
    15661 ttcttgaaaa agtgatgtag atttatagcc cataactttt ttgaattaca tcgacgatac
    15721 ggcgtcgaaa gaaaaagcta cctcacttta tctggggggg cttttatttt ttatgccctt
    15781 attttgaatt ttaagagggc attttaaaga tttaggggtg attcatatag ttttatatct
    15841 aaaacttata tacgctttta aaacgcaaat atgagccaaa taaatatatg ctattttcaa
    15901 aaacaaaaat ttgagcaaaa acaataacta ttttttagac actgcccatt tacatgcaaa
    15961 ttaaaaatta gcataaaatt ctttaaaact tccccacgtt cttctaaatt cctgcagggc
    16021 ttttcttatc aaaaacttag aaattttaat ttaactctaa aatctccgta agagcataag
    16081 ggaaatttgt ccccatcaat gaatggggga tctggcaaag ccagatattt caaggcttcg
    16141 aaaatgtttt tgtgtggggt cataaaaagc tcaagtgtca cacttttgtg acactacata
    16201 cagcatttgt cacaaaaata agacagcact ttttttacaa aaaagtaata aaaaaagaca
    16261 tcagttatca ctaatgcctt aaataataat tttgcttttc aaaattgccg taatcgaatg
    16321 tgccttttct tcttcatttg ctattttatc ttcatcactt gtattaatta aattgccatc
    16381 ttcagcatcg tctaagttta aaattttatg tttttattta agcaatccac cataacttaa
    16441 catacgtttt cgatacaaat ctttttctag atcactgaca atttcttgat tttttcatcg
    16501 ctatcagtta aaaagtcaga tgatttaacg aaatattttg atgtatcttt gattgttata
    16561 aaatcatttg aatgattgat taaagatatt atattgtttc atgtttttac ggcgcatata
    16621 aagtgcatgt gtttcttcaa attcagttaa aattgtttgc attaaataac cttgcattga
    16681 cttgaatgat tactaatttc attttcggac tctatatcat tcaagtcatt catatcattt
    16741 atttcagtat tgttagattc agtatagcta agttcagtat cattagattc tgttttatcg
    16801 acttcttgaa gtcggttttt ccgacttcct tgccattgct gctctcaaca gtgttttctt
    16861 gcttttgaat tttataaata tcatcttctg ttacttctgg tttaactaaa taaagtttat
    16921 ttgtcttatt taaaccttgt ctttcttgta gtagtaattc ggcttcaatt aagttctttc
    16981 tttattttaa ttactttatc ttttttacaa tttaatacat tttgtgggtt ttcatttttg
    17041 taataaaaat aaatattacc tgttttagaa tcaacccaac catttttaat tgataaatct
    17101 aaacgatctc taagaatacc ccatgccatt tttgcatcat tggataactt gatatattta
    17161 ggatttgtaa aaaatacttt cggtatttga taaaactttt ctctgtattc ctcatttatg
    17221 ttgtaaagtt taattgacat aataaaaacc tctttccgaa ttttagtttg gtaagaggta
    17281 ataaaacgct tacatttttt gtgtttattt aataatctag gtgcttgcac taagatatta
    17341 ttcattatat aatctaagta tcgaaaatta tataaataaa cagtttctaa acgttttatt
    17401 accaaacccc gactattacc agtagttggg gtttttgtta tattaaggtt attatagcac
    17461 tttgaataaa cttaaaaaag ggaaaatata ggtttataaa cctttgataa acaccataaa
    17521 ccctttacaa acccttgata aaaaggttgg cgaatttata tttttatttg tcgattactt
    17581 tattattaat cgttataagc ttataatatt ttactaaggg tttataaaca ttttataaag
    17641 ggttgatgat atgaaaagtg taaaaaggtt gagtgaagaa ttaggggtta gtaagcaaac
    17701 gatttttaat aatattaaga gattgaatat agagacaata aaacaggaaa acacttcgtt
    17761 tattaaagaa gataccgata tagaaaaaat cattcaaaga gtaaatgaaa ataaaaagaa
    17821 atatggtttt gaaagtgcta ctgaagacaa acaaaaaaaa gagtcggata atattaattt
    17881 tgaatctaaa agcgatgctc aaatagtaga aatacttaaa aatcagatta atactttaaa
    17941 taatcaaatt gaaaaacaag aaagtcgtca tgaaacaaca attgaatttt acagaaaaga
    18001 gttgcaagaa agatcaaaat tgcttgagaa tcagcaagtt ctggcattag agagtaataa
    18061 aaagattcaa aaattagaaa atcaattaga aaaagaaaaa caccttaatt atccctttga
    18121 tacatctact aacgctagac aaaacgttga tgcacaagaa aaaacatata ctactagtcc
    18181 tgtaaatatt aaccgagatc aggaagaaac taaagaaaca gagattcaat ataaggatat
    18241 atctggaagt caaagcgacg aaagtacaca aggtgaagaa gcacaaagag aagacgtttc
    18301 agctaatcca aatgacaatg atagtgatat agaagaaaag agtgaagaaa cggaacctaa
    18361 aaaggggttt tggagtcgtc tatttggtaa ctaattttaa ttaaaaaggt acgacaagtt
    18421 cataaattag ccgtgctttt ttatgtgaat tgaacttctg ataatcatcg attatgttaa
    18481 ccaaacaaaa agccataaat gcctatatga cggcatttat ggctttttac tttcattatc
    18541 ttttatgcat cttttataca tcgttgattt gacgcgtttt cattcttttg cattggcaag
    18601 tattttgtat ctttattcag ttactatttc ttttctccaa cctaacaaac catctttaac
    18661 tctaataata tgtttgccac gccagacact tcttacttcg aaataatacc attccccgtt
    18721 tttgttgagg aaataaatat cttgataacc ttctttaatg acatattttg tagcttcttg
    18781 tctttgatcg ccaaacatta tcaatcccac ccttatattt atttatcttt aatatataac
    18841 aacatttatt aatattcatg ttatttcatg gaaggagaga tttgttataa tgtgaaggtc
    18901 gtctatctct cagatgtcaa ttcggcgtaa agaggaggtg cgatttatga atgaaattct
    18961 tgttcacatc atgacaacgg caatcagtgg ttgtctcgtt acgttatttg gttattagct
    19021 ccataaacgt gataaaaaat aatatagacg attaaagcca attcaccaaa aaaccccgaa
    19081 ctacggcgaa tagttcgggg ttttgtgcgt ttacaaacga aattcttgtt acttttagta
    19141 tatatttcat attgcctttt gtaaactctt ctattcttat caatacattt caaggtgtcg
    19201 taaaaatact ttcctttttc atattgcctg atgtgcatta aattttgatt ttaaaatcaa
    19261 cccatgaacg aatgaatggc ccaaactaaa aatccggcaa caggaaagaa aagccaccaa
    19321 aaatcataaa gaaaatcaac tatggaaggt accctgttac tctctctata atttccctct
    19381 aaaataactt ttttaaaacg tgcatctcct ttaattaaat gctctaaaga gattccgaat
    19441 aaatcgctca tagcaatcaa aatatctaag gaaggatagt ttttggcact ttcccattta
    19501 gaaacacttt gtctggaaac ctttaatata ttggctaatt cctcttgaga ccatcctttt
    19561 aattctctct gttcttttat agcttcagct aatttcataa aatcactcct taactcaaac
    19621 tataattaaa ataattgaaa agtcacgata cttttagtta accaactcgc aacgaaaagt
    19681 tgcgttattc ccaattcagt tcaagttgtt ttaaaaaatc ctctcgttct ttctctaatt
    19741 gtgggtcgta atctttttga ggttgctttt catatgaccg ttcttctaac catttaggcg
    19801 tcttttcacg cctcacatat tgtcttgatt tatctatctt ggacatttga ggttgtcgtt
    19861 tgttatgaat gcgtttctca gcgtcaaatg tgaactctat ccattcaatt ttacgccctt
    19921 ttttcgcttt gattttattg atagtaagat tattaaatat agaacctaat tcaataataa
    19981 taggtttaaa aacatttttg ttaatatcag tcatacgata agatttaggt atatctaaac
    20041 gatttttaaa atcatcgatg tgaattttta aatagcctgt atgtttgtat tgtttaagta
    20101 atctaaacat atttttagaa tatgtagatt taagcctagt catttctttt aattcaaatt
    20161 ttgtaaaatt attagtaatt gaattcaata tgtgttttaa atttgaagaa gttgatattt
    20221 ctagatattg ttctcgctta tggattctat aatgattgaa taaaacgaat ctttctatta
    20281 catcatcatc ttcatatcta atggttaaat tcaacatctt tttatacaca ttatctaaat
    20341 cattagcaaa tctattaata ttacgtgttt ctggactata attacttaat ttttttaatt
    20401 catcaaaaga caaacgtaat gtattagtat cttgctcttt taatttatta cacatcgcaa
    20461 aaaataaatt aatttcagta gctgtaaatc gccttaatgg aactaaattc atttcatttt
    20521 tatatacaac tgtctctcct gtcatgatac agcccccttt attacgaacc taaaggagta
    20581 tcgtttgaat atacactccc atttgaaaac ttttattcac aataaactac tttattatca
    20641 atgtcaaacc ataaaaggag tacaactttt taaaacactc cttttatgtg gcaaaaacac
    20701 tcctttt
//
