LOCUS       NZ_CP120002            20730 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Staphylococcus aureus strain Dog165 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP120002
VERSION     NZ_CP120002.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33696837
            Assembly: GCF_034042935.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Canine Staphylococcaceae circulating in a Kenyan animal shelter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-DEC-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
  REMARK    Annotation added by database at the request of the submitter
REFERENCE   3  (bases 1 to 20730)
  AUTHORS   Akarsu,H., Liljander,A., Lacasta,A., Ssajjakambwe,P., Brodard,I.,
            Cherbuin,J., Kuhnert,P., Perreten,V., Torres Puig,S., Labroussaa,F.
            and Jores,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-MAR-2023) Institute of Veterinary Bacteriology,
            University of Bern, Langgassstrasse 122, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Flye v. v2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 909x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/06/2024 11:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,736
            CDSs (total)                      :: 2,654
            Genes (coding)                    :: 2,586
            CDSs (with protein)               :: 2,586
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 34 of 68
            Pseudo Genes (incomplete)         :: 33 of 68
            Pseudo Genes (internal stop)      :: 20 of 68
            Pseudo Genes (multiple problems)  :: 18 of 68
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Dog165"
                     /isolation_source="nasal swab"
                     /host="Canis lupus familiaris"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="Kenya:Nairobi"
                     /lat_lon="1.3345 S 36.7331 E"
                     /collection_date="2015-06-27"
                     /collected_by="Joerg Jores, Anna Lacasta, Anne Liljander,
                     Paul Ssajjakambwe (International Livestock Research
                     Institute, ILRI)"
     gene            complement(join(19810..20730,1..522))
                     /locus_tag="P3U47_RS13550"
                     /old_locus_tag="P3U47_13550"
     CDS             complement(join(19810..20730,1..522))
                     /locus_tag="P3U47_RS13550"
                     /old_locus_tag="P3U47_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_054192781.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISESKGI
                     ALSTLYRWNKSYKEQGLKGLIYATRADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     ITNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDLQHARSQRRKHLKQNIASPSTTELIKKEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(494..1087)
                     /locus_tag="P3U47_RS13555"
                     /old_locus_tag="P3U47_13555"
     CDS             complement(494..1087)
                     /locus_tag="P3U47_RS13555"
                     /old_locus_tag="P3U47_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_054192780.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERSVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKKDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(1351..1731)
                     /gene="blaI"
                     /locus_tag="P3U47_RS13560"
                     /old_locus_tag="P3U47_13560"
     ARG             complement(1355..1731)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(1721..3478)
                     /gene="blaR1"
                     /locus_tag="P3U47_RS13565"
                     /old_locus_tag="P3U47_13565"
     ARG             complement(1725..3478)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="96.07"
                     /coverage="100.0"
     gene            3585..4430
                     /gene="blaZ"
                     /locus_tag="P3U47_RS13570"
                     /old_locus_tag="P3U47_13570"
     ARG             3586..4427
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4799..5407
                     /locus_tag="P3U47_RS13575"
                     /old_locus_tag="P3U47_13575"
     CDS             4799..5407
                     /locus_tag="P3U47_RS13575"
                     /old_locus_tag="P3U47_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            5821..6114
                     /locus_tag="P3U47_RS13580"
                     /old_locus_tag="P3U47_13580"
     CDS             5821..6114
                     /locus_tag="P3U47_RS13580"
                     /old_locus_tag="P3U47_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            6189..8123
                     /locus_tag="P3U47_RS13585"
                     /old_locus_tag="P3U47_13585"
     CDS             6189..8123
                     /locus_tag="P3U47_RS13585"
                     /old_locus_tag="P3U47_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            8127..8438
                     /locus_tag="P3U47_RS13590"
                     /old_locus_tag="P3U47_13590"
     CDS             8127..8438
                     /locus_tag="P3U47_RS13590"
                     /old_locus_tag="P3U47_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            8450..9076
                     /locus_tag="P3U47_RS13595"
                     /old_locus_tag="P3U47_13595"
     CDS             8450..9076
                     /locus_tag="P3U47_RS13595"
                     /old_locus_tag="P3U47_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            9314..9943
                     /gene="mobV"
                     /locus_tag="P3U47_RS13600"
                     /old_locus_tag="P3U47_13600"
                     /pseudo=""
     CDS             9314..9943
                     /gene="mobV"
                     /locus_tag="P3U47_RS13600"
                     /old_locus_tag="P3U47_13600"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            10037..10582
                     /locus_tag="P3U47_RS13605"
                     /old_locus_tag="P3U47_13605"
     CDS             10037..10582
                     /locus_tag="P3U47_RS13605"
                     /old_locus_tag="P3U47_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            10966..11826
                     /locus_tag="P3U47_RS13610"
                     /old_locus_tag="P3U47_13610"
     CDS             10966..11826
                     /locus_tag="P3U47_RS13610"
                     /old_locus_tag="P3U47_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            11913..12254
                     /locus_tag="P3U47_RS13615"
                     /old_locus_tag="P3U47_13615"
     CDS             11913..12254
                     /locus_tag="P3U47_RS13615"
                     /old_locus_tag="P3U47_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(12493..12564)
                     /locus_tag="P3U47_RS13620"
                     /old_locus_tag="P3U47_13620"
     CDS             complement(12493..12564)
                     /locus_tag="P3U47_RS13620"
                     /old_locus_tag="P3U47_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            12713..12898
                     /locus_tag="P3U47_RS13625"
                     /old_locus_tag="P3U47_13625"
     CDS             12713..12898
                     /locus_tag="P3U47_RS13625"
                     /old_locus_tag="P3U47_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(13117..13860)
                     /locus_tag="P3U47_RS13630"
                     /old_locus_tag="P3U47_13630"
     CDS             complement(13117..13860)
                     /locus_tag="P3U47_RS13630"
                     /old_locus_tag="P3U47_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            14271..14947
                     /locus_tag="P3U47_RS13635"
                     /old_locus_tag="P3U47_13635"
                     /pseudo=""
     CDS             14271..14947
                     /locus_tag="P3U47_RS13635"
                     /old_locus_tag="P3U47_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <14958..15240
                     /locus_tag="P3U47_RS13640"
                     /old_locus_tag="P3U47_13640"
                     /pseudo=""
     CDS             <14958..15240
                     /locus_tag="P3U47_RS13640"
                     /old_locus_tag="P3U47_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            16452..17069
                     /gene="cadD"
                     /locus_tag="P3U47_RS13645"
                     /old_locus_tag="P3U47_13645"
     ARG             16453..17066
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            17088..17435
                     /locus_tag="P3U47_RS13650"
                     /old_locus_tag="P3U47_13650"
     CDS             17088..17435
                     /locus_tag="P3U47_RS13650"
                     /old_locus_tag="P3U47_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            17604..17696
                     /locus_tag="P3U47_RS13655"
                     /old_locus_tag="P3U47_13655"
     CDS             17604..17696
                     /locus_tag="P3U47_RS13655"
                     /old_locus_tag="P3U47_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            17908..18882
                     /locus_tag="P3U47_RS13660"
                     /old_locus_tag="P3U47_13660"
     CDS             17908..18882
                     /locus_tag="P3U47_RS13660"
                     /old_locus_tag="P3U47_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_054192782.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKNLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(19002..19817)
                     /locus_tag="P3U47_RS13665"
                     /old_locus_tag="P3U47_13665"
     CDS             complement(19002..19817)
                     /locus_tag="P3U47_RS13665"
                     /old_locus_tag="P3U47_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     ARG             3586..4430
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             821..11114
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          15298..15445
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          10967..11826
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13118..13860)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9315..9589
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 tataaagata tctagcaaag tatggtctgc ttgccatatt tcattgggtc tcgaggattc
       61 tctaatttgt attaaatcgt acttattttg atagtatttt tcaccctgat gagagaaatc
      121 aataacagac ttaggcatcg ctttaataac actataaatt tgtttataac ttggtatatc
      181 aaaattattt tctttacagt aattagtgat tttcctatga attgtggcta tactatttct
      241 tttattcata agcgcaaggc gttcaatttc atcaattatc tttggttcta ttttacgtgt
      301 tcctttatca gctcttgtcg catagattag ccctttaagt ccttgttctt tatatgactt
      361 attccaccta taaagggtgc ttaacgcaat ccctttactt tcagaaatac ttgataaaga
      421 ttgttcgcct aggataaaag gttttataat attgtacttt tgagtagctt ttttacgttt
      481 ggcttcagaa aaattagtta gatacttctc cttgtttttc atctttcttg tcctccaatt
      541 tattgaggta acgataaatt gttgtacgtg aaacatgcca ctgttctgca attgtcttga
      601 ttggcgtgcc attatcataa agtgtcttaa gtaagtttaa atctttttga tttaattttt
      661 ctggtctgcc tccatatcgg cctctagcac gtgctgcaat tctgccagct gaagaacgtt
      721 ctaaaattaa attccgttca aactctgcaa atgctgcgaa taaatgaaat aataattgtc
      781 ctgtagaact tgatttatcc atggttatat tttcttctaa gctatggaaa ctcacgcttc
      841 tctcattaag ttcattaact aatgtgatta aatcttccat attacgtccc aatctatcta
      901 atctccaaac aacaatcgta tctcctgacc tcgcaaattc aattgcttta tctaaaccag
      961 gtcttttact ttttgaacca ctcatatggt cattaaatat cttttcacaa ccatatgtat
     1021 ttaatcgatc ctcctgtaaa tttaaatttt gtaatccagt tgaaactctt gcataaccta
     1081 ttttcaaaat acaaacctcc tatatacatc ttcagtgtac cataacttaa ttacaaggcc
     1141 ttttatgaac atagattttt tattgggttt ttgaacacat aatcctatgt aattcttact
     1201 tatttagaca taaaagaaga gtgtacagaa aatggttatt ttctgtacac tctcatcttt
     1261 aataatatat tttaaatgtc attaacaaaa ctaatttaat aagagtcaag catagtttac
     1321 atatgtatta tgtttgaaac atacctctaa ttacttttta ctaatatcat ttaaaatatc
     1381 tcgcaattct tcaatttctt tgttatttaa ttcttcattt ttcgcaaaat tcaacactaa
     1441 acttttcata tcccctccat acagtttatt aagaaaggtt ttagcagttt tcattttaat
     1501 atcgtcttct ttaatatttg atgagtaaaa ataaatattt tctgatttgt atcgttttat
     1561 aatctctttt ttatatagtc ttgtgattaa tgttctaatc gttttatcac taacttcttt
     1621 atatttttga atttcaacta caatttcatt agctgatact gattttttat cccatattat
     1681 attcataaca tcccattcag ccatagatat ttcaacttgc ttattggcca tttaaaacac
     1741 ccattccttt taatattttt tcacttatta attcagcatt tttcccagac gggtttccat
     1801 ctgataaatg tgtagcaaaa taatacttat catgatttgt aattacgtaa cctacaaacc
     1861 acccattatt atacttcccg tttactatac ctgtacctgt tttcccatac agttcatact
     1921 tttcattttt cttaatcaat aatgaagaag ataattgatt ctttgctttt ttactaaaat
     1981 ggttattttg ttccatcata tttttaaaaa ctattacttg ttcaagatta gatattttca
     2041 aactatcttc catccaatag cttttataac ttcccaaatt ttcattacca taatttaatt
     2101 gcttgagttg agccgcagta tagttctttg gtatttgatt actaatacgt tcgaagtacc
     2161 aattaactga attttgcatt gctgtattta aatcttgttc cttattccaa gactcgaaaa
     2221 gataatgttt atgattccat gacatacgtg aatttttatc acttataata tgacggtcaa
     2281 gtccaaacag tgctaaataa attttgtaag ttgaatcagg agaatatctt tttctacttt
     2341 ctttttcatt ataaatatag tatttgtctt tcttcatgct gtacataacg aaagatccac
     2401 tatttgaacc aaaattttta ctttcatcta aaatttggta atcgctttgt aagggctttt
     2461 tataattata atcagttaag gattgcccca ttaaaaactg gctttgaatt atcatgataa
     2521 aaaaagtaaa aatacaaata aaaattagaa ttaattttga ctgctttttc agatcggctt
     2581 cttttatatt aattaatctt cttttgagta atgacttttt accattaaat gaatggctta
     2641 atatattttt attaaaaaat ggaacattta atacggagtc cataatagat tccgcataag
     2701 ttttaaattc atttttgtta atattattaa ggacaaatct atcggcttct acttcattgt
     2761 catgaattat ctttcttttt acaatatgta ctaatggatt gtaactcata ataatagaga
     2821 agatattaaa gataattaaa tgtaaagtat ctctattttt agcatgagca tattcatgca
     2881 gtattatata ttttagtctt ttatcaatta cacttttaaa atatgaacta ggaatcaaaa
     2941 taatatattt cccataccaa aaagttattg gagattgaat agcctctgct tttcgaatca
     3001 caatattttt tttatattga tggttgaaaa gtatcgtatc tattttattt ttttcatttt
     3061 cgtttagata aagtgactgt ttctttaaat atttaagata taataaggct ttcaaaaatt
     3121 taaaacttaa aataataact aaaactatcc aaataactgt gcagatatta tcaattgaat
     3181 cccaattaaa cttatggata tctgttgcga actcttgaac aggtttggtg gtaattatgt
     3241 tatggttcaa gtcgtgtgac ttactttcaa ctgtgggcgc ttgattattc acattattaa
     3301 attttataaa agagaattta attgggataa aaggaattaa tccagcaagc acagttagat
     3361 accaaacttt ataatttaaa ctataattaa aatagcgttt taatatgtac ctaaaaaata
     3421 ctaacaatag aaatataaaa caaaagctta ctacactcat tattagtaat ttagccattt
     3481 tgacaccttc tttcaaatat ttataataaa caattgacat caatattaca attgtaatat
     3541 tattgttttg taaaaattac aactgtaata tcggagggtt tattttgaaa aagttaatat
     3601 ttttaattgt aatggcttta gttttaagtg catgtaattc aaacagttca catgccaaag
     3661 agttaaatga tttagaaaaa aaatataatg ctcatattgg tgtttatgct ttagatacta
     3721 aaagtggtaa ggaagtaaaa tttaattcag ataagagatt tgcctatgct tcgacttcaa
     3781 aagcgataaa tagtgctatt ttgttagaac aagtacctta taataagtta aataaaaaag
     3841 tacatattaa caaagatgat atagttgctt attctcctat tttagaaaaa tatgtaggaa
     3901 aagacatcac tttaaaagaa cttattgagg cttcaatgac atatagtgat aatacagcaa
     3961 acaataaaat tataaaagaa atcggtggaa tcaaaaaagt taaacaacgt ctaaaagaac
     4021 taggagataa agtaacaaat ccagttagat atgagataga attaaattac tattcgccaa
     4081 agagcaaaaa agatacttca acgcctgctg ctttcggcaa gactttaaat aaacttatcg
     4141 caaatggaaa attaagcaaa aaaaataaaa atttcttact tgatttaatg tttaataata
     4201 aaaacggaga cactttaatt aaagatggtg ttccaaaaga ctataaggtt gctgataaaa
     4261 gtggtcaagc aataacatat gcttctagaa atgatgttgc ttttgtttat cctaagggcc
     4321 aatctgaacc tattgtttta gtcattttta cgaataaaga caataaaagt gataagccaa
     4381 atgataagtt gataagtgaa accgccaaga gtgtaatgaa ggaattttaa tattctaaat
     4441 gcataataaa tactgataac atcttatagt ttgtattata ttttctatta tcgttgacat
     4501 gtataatttt gatatcaaaa cctgattttc cctttattat tttcgagatt tattttctta
     4561 attctcttta acaaactaga aatattgtat atacaaaaaa tcataaataa tagatgaata
     4621 gtttaattat aggtgttcat caatcgaaaa agcaacgtat cttatttaaa gtgcgttgct
     4681 tttttctcat ttataaggtt aaataattct catatatcaa gcaaagtgac ataattgttg
     4741 aatttatagt aactgaaacg tatgattagg gtgtatatta attatgagat ggaaatcaat
     4801 gattgttggc tatgcgagag tatcatcgaa cgatcaaaat ttagaaagac aacttgaaaa
     4861 tttaaagacg ttttgtgctg aaaaaatatt tacagaaaaa cagtctggga aatctattga
     4921 aaatagacca gtacttcaag aagcacttaa ctttttgagg atgggagatc ggtttgtagt
     4981 agaatccatt gattgtttag gtcgtaatta tgatgaagtg attcataccg ttaattattt
     5041 aaaagacaaa gaagtacaat taatgattac tagcttacct atgatgaatg aagtggttgg
     5101 caatccatta ctggataagt ttatgaaaga tttaattatt caaatattag caatggtttc
     5161 agaacaagag agaaatgaaa gtaaacgtcg acaagcgcaa ggaattcaag ttgcgaagga
     5221 aaaaggcgta tataaagggc gccccttact ttattcacca aatgctaaag atccacagaa
     5281 acgtattatt tatcatcgcg ttgtagaaat gttagaagaa ggccaatcaa ttagtaaaat
     5341 tgcgaaagaa gtaaatataa caaggcagac gatttacaga attaaaaacg ataatgattt
     5401 gatttaataa actttgtttc aatgcaactg agagcttctc acagcgtctc aaaacagatg
     5461 attataatct attatgagtt tttaataata agacaagaaa agagagcgta aatatgctct
     5521 ctctttttct cattaacgaa tgtttataac gcaatcatga tgagagtatt aatacagtta
     5581 attatttgaa atactttagt ttatataatg ttgaattata ggtagtgaaa ttgtatttat
     5641 tatacattgt catatcgttg tttaatgata gttaatttaa ggataataga attaatatta
     5701 tatatagatg aacaaaacaa gcaacagagc agaaaaaaca cttttagatt atttttactc
     5761 attctctatt ttatttattt ttgctataat aaataaagaa tattaaatgt aggtgttttt
     5821 atgaaaaaga aatttgtttc tagttgtatt gctagtacaa tcttattcgg cactttatta
     5881 ggtgtaactt ataaagctga agctgcaaca gtacatgtag ctggtggtgt ttggagccat
     5941 ggtattggaa aacattacgt atggtcttat tatagtcaca ataaaagaaa tcatggttca
     6001 acagcagtag ggaaatattc atcttttagt ggtgttgctc gacctggtgt tcaatctaag
     6061 gcatctgctc caaaggcttg gggtggaaac aaaacatttt atagtcttca ctaattacat
     6121 atattaatta aggagaatag acagaattaa gtaaacttaa ttctgtctat tctcttgaaa
     6181 gaggcaatat gaaaaaattc aaattatttt tagattttag tactttatta ttaatttcag
     6241 ggctattatt tttatttttc ttcaaagaaa atgaagaaat tatacctgaa agttccaata
     6301 ttttaacaat ctctaattgg gataaatcta acagtaaatc aaaagtgtta gatgtcattg
     6361 aatcaggcgc caaaaatcaa aatatacaaa taattaaatc cgttaaagat tttgataata
     6421 aaaaagaatt ttttgttttc aactcaaaac gaaataattc tgactttata cgtaataaaa
     6481 catcactttt aactccatca gatttattaa acagagagat aaaaggaaag tattatatta
     6541 ttggtgaaca tttcaatgta gaagagctta cgagtgaatt aaaaaaagct ggtttaacat
     6601 ctgaagttga atacataaat agaaacatat tattttttga attagtcata gataatgatt
     6661 tattagtgcc tttcatattc ttaggcgtat tatatctttt gtacttctta tatgacagag
     6721 gatataattt gaaattttat gctattcaaa agctacatgg cttttcaact acacgcatta
     6781 tttttcataa tattcatata aaaatcattt attggctagt acttaccgct attttcttta
     6841 ttgctaatat attaatcatt catatagcca atttagaatt ggatttctta atgtttattc
     6901 gtagatttat cgtgttgctt tttgtttttg cttgtattac tacattgctg tggctgattt
     6961 cgtatagtct tcttttgaag ttaagtattc cattaatctt aaaagggaaa aaaggatata
     7021 agttttcaat atttatgggt accttcacca aatgtatcat ggtgctaata ctatcttttt
     7081 tactggcaca aaatttaaat gcttatacga agttaaagaa tatatatgac tctgaaaaaa
     7141 tctggcaaaa gttagataat tactatacat tagagatttc tcctaatatt agaaattcag
     7201 aagaaaaaca aattttagaa actaatatat acaatttaat taagaaaagc gaacaacttg
     7261 gtggattgct tttaaagaat aataatatag ccaatcccga taaaaacaat tacattcctg
     7321 aaaatggcaa tgtctttttt atcaataaca attttctgaa tttctataaa aatataaatc
     7381 atgattttaa aatgattgac aatcattcgg ataaaataaa cgtgtttatt cctccaaggt
     7441 tacaatatca aaaatctgaa attcaaaaaa atcaccaagg atggattgac tttcaaaagc
     7501 aacaaaacaa aaaagtagat gtgcaagtac tgtcaaaaaa cgtatctgtt ttttcttttg
     7561 atcgcacaac taatttgaaa tttgggtatc tagattctcc aatagtaatg ttgttgacac
     7621 ttgacgattt aacaggagat ttttatttag ctgctgtttc tcaaggtgga tatctattta
     7681 aagatttaga tacacttaaa cagttgctta aagataatca cctagaagaa gaaattagcg
     7741 gtataactaa ttacaaggat tctgtgttaa atgaattaaa tgaaacgaaa acaaaaatga
     7801 taataacaat agttactatt attattaacg ttttcattct tttgatagct actgtatttg
     7861 aaacaattca atattttagc tggaataaaa agcaactatt attaagaaaa attcatggtt
     7921 attcattatt cagcagtaat gtacgttatt taacaatttc tatcttactt tctattatgt
     7981 tagcttacac tacgcatatt ttatttggtt caaagatatt actattcata ataatgtcta
     8041 ttgctattat tcaacattta cttcaaattg cttatattaa atatcttgaa aaatacttta
     8101 aagatttaat gagggagatt taaacaatga aaagaacttt aattattgta acaattgtac
     8161 tattaatcat catacttagt ctgttattgg ttagaaatga gcatttagat cgttttaacc
     8221 cactgttaaa agaaaaagta tcttatgcca aagttccaaa agatacccag gactatagaa
     8281 atataactgt atactctaaa aatggagaaa aaaagagtta taaattggat tttttaggtt
     8341 atgatcctac aaaagaatat gtgaaagtaa atcataaagg gaaatatgtg cgttcgatag
     8401 aatacattac aaaagatatt cctagctttt taaaatgagg tgaccgatag tgataaaact
     8461 tgaaaatgtt tttgtaaaaa aaggtaataa aaacatttta gacggatgta actttaattt
     8521 tgaaaaagga aaatcatatg ctttagttgg agaaagtggc gctggaaaat ctactttact
     8581 taacataatc gctgggttcg aagatgtatc acaaggaagc atatatattg aagataagtt
     8641 actaaaaaag aaagtcgatt tttatagata tacgttaggg tatttgtttc aaaattttgc
     8701 tttacttgaa aatcaaacaa tcagtcaaaa tttagattta gccctaaagt tcaaaaagaa
     8761 taaaaaagat aatatgaact taaagaaaga agtattaaaa aaggtcggcc tagatttaga
     8821 tatcaagaga attgttagtt ctctaagcgg tggtgaacaa caaagagtag cattggcaag
     8881 attaatatta aaagatccga aaatcatttt agctgatgaa cctactgggt cactagatac
     8941 gaaaaatgga aaaatagtta ttgatttatt attgaagcta cttgatgaaa ataaaactat
     9001 gattgtcgta acgcatgatt tagagcttgc gaaacgattt gatgtcatag tcaatatttc
     9061 tgagcttaga agttaagaaa tattgatagg tatagccata catagagaaa aaacaatatg
     9121 aaatatgatt agtcattact tttgagtttt ttaatttaag gactggattt tccagtcctt
     9181 ttttatgatg acaaaaaaca agcctcgcag agcacacgtt tttaatgact tatttggttt
     9241 ttaataagtc tagtatgtta aaacttttct gtgtttaggt gttataatca tatgcagtgg
     9301 aagttgattt attatgtctt attcaattat tcgagttgtt aaagtgaaat caaaaacaaa
     9361 tacaagaggt attcaaagac atattcaaag agaaaataaa aattatgaaa atatagatat
     9421 tgatttaagt aagtcatatt taaactatga tttagtcaat gatactaagt ttgattttaa
     9481 taaaaaaatt gatgagaaaa tcgaaaaaaa ttataaaggg aaacgcaaaa ttagaacaga
     9541 tgccattaaa catattgatg gattaattac atcagataat gtgtttttta atcaattatc
     9601 tgaagaagag acaaaatagt tttttaagca tgctaaagcg ttcttggaag aagaatacgg
     9661 taaagaaaat cttttatatg cgacagtaca tatggatgag ataacaccac atatgcatta
     9721 tggcgtagtt cctattacta aagatggacg tttaagtgcg aaagaagttg taggtaataa
     9781 aaaagcatta accgaattcc aagatagatt caatacgtat attaataagc aaggctatga
     9841 tttaaaacga ggaatttcta gacaacttac aaaagaaaaa catgatcaag ttagccgtta
     9901 taaacaaaaa acagaatatc ataaacaaat gcatatgcgc tagaagcaaa tagaggatta
     9961 tttaaagcaa gaaaatgata aattgataca aaactaccaa aaatcattag atacgcttaa
    10021 aaagcttctg agtgtcatgt atgaaattaa aactaaaaat gtaggtggat ggtttcataa
    10081 agagaagcaa gaaacaggca atattgtaat tactaaaact gattttgaaa aatacactaa
    10141 acaaattaaa gcagcacaga tgatattaga tgattatgaa tgtattaaaa gtgggaagtc
    10201 attaaaaaaa gcagagaaac aaaatgaaag tttagttaat gaattgacta gtgtccatat
    10261 ggaaaatgaa aagctggttg aagaatttaa tgatttagca caacgttata attatttgtt
    10321 gtcagagaat gaaaagaaag ataaagaact aaattatacg cttaagttat tcaatcaagt
    10381 ttttaaaatc attaaaagta tgatgaaaga agagcgttat catacactaa taaatcatat
    10441 tgataatcat ttagacaatt ctaaaatacg tgaagtaatg acgatagata acaatgatga
    10501 acagttcttt aagaagaaat atcaagcaca agaacgagaa atcattttta aagaagatag
    10561 agaagatggt tatacattat aaaaatagat atttaaatgc atttgtttga ggttaattat
    10621 tttttaggat gaaaaatagg tagcccccct cgaacttttt aatatatttt tataaatctt
    10681 tttaaaaacc tttttagggg cttgttcagc cctagagcaa caagggattt caatgcctaa
    10741 aggagtgttt ttgccacata aaaggagtgt ttttgccaca taaaaggagt gtttttgcca
    10801 cataaaagga gtgtttttgc cacataaaag gagtgtttta aaaagttgta ctccttttat
    10861 ggtttgacat tgataataaa gtagtttatt gtgaataaaa gttttcaaat gggagtgtat
    10921 attcaaacga tactccttta ggttcgtaat aaagggggct gtatcatgac aggagagaca
    10981 gttgtatata aaaatgaaat gaatttagtt ccattaaggc gatttacagc tactgaaatt
    11041 aatttatttt ttgcgatgtg taataaatta aaagagcaag atactaatac attacgtttg
    11101 tcttttgatg aattaaaaaa attaagtaat tatagtccag aaacacgtaa tattaataga
    11161 tttgctaatg atttagataa tgtgtataaa aagatgttga atttaaccat tagatatgaa
    11221 gatgatgatg taatagaaag attcgtttta ttcaatcatt atagaatcca taagcgagaa
    11281 caatatctag aaatatcaac ttcttcaaat ttaaaacaca tattgaattc aattactaat
    11341 aattttacaa aatttgaatt aaaagaaatg actaggctta aatctacata ttctaaaaat
    11401 atgtttagat tacttaaaca atacaaacat acaggctatt taaaaattca catcgatgat
    11461 tttaaaaatc gtttagatat acctaaatct tatcgtatga ctgatattaa caaaaatgtt
    11521 tttaaaccta ttattattga attaggttct atatttaata atcttactat caataaaatc
    11581 aaagcgaaaa aagggcgtaa aattgaatgg atagagttca catttgacgc tgagaaacgc
    11641 attcataaca aacgacaacc tcaaatgtcc aagatagata aatcaagaca atatgtgagg
    11701 cgtgaaaaga cgcctaaatg gttagaagaa cggtcatatg aaaagcaacc tcaaaaagat
    11761 tacgacccac aattagagaa agaacgagag gattttttaa aacaacttga actgaattgg
    11821 gaataacgca acttttcgtt gcgagttggt taactaaaag tatcgtgact tttcaattat
    11881 tttaattata gtttgagtta aggagtgatt ttatgaaatt agctgaagct ataaaagaac
    11941 agagagaatt aaaaggatgg tctcaagagg aattagccaa tatattaaag gtttccagac
    12001 aaagtgtttc taaatgggaa agtgccaaaa actatccttc cttagatatt ttgattgcta
    12061 tgagcgattt attcggaatc tctttagagc atttaattaa aggagatgca cgttttaaaa
    12121 aagttatttt agagggaaat tatagagaga gtaacagggt accttccata gttgattttc
    12181 tttatgattt ttggtggctt ttctttcctg ttgccggatt tttagtttgg gccattcatt
    12241 cgttcatggg ttgattttaa aatcaaaatt taatgcacat caggcaatat gaaaaaggaa
    12301 agtattttta cgacaccttg aaatgtattg ataagaatag aagagtttac aaaaggcaat
    12361 atgaaatata tactaaaagt aacaagaatt tcgtttgtaa acgcacaaaa ccccgaacta
    12421 ttcgccgtag ttcggggttt tttggtgaat tggctttaat cgtctatatt attttttatc
    12481 acgtttatgg agctaataac caaataacgt aacgagacaa ccactgattg ccgttgtcat
    12541 gatgtgaaca agaatttcat tcataaatcg cacctcctct ttacgccgaa ttgacatctg
    12601 agagatagac gaccttcaca ttataacaaa tctctccttc catgaaataa catgaatatt
    12661 aataaatgtt gttatatatt aaagataaat aaatataagg gtgggattga taatgtttgg
    12721 cgatcaaaga caagaagcta caaaatatgt cattaaagaa ggttatcaag atatttattt
    12781 cctcaacaaa aacggggaat ggtattattt cgaagtaaga agtgtctggc gtggcaaaca
    12841 tattattaga gttaaagatg gtttgttagg ttggagaaaa gaaatagtaa ctgaataaag
    12901 atacaaaata cttgccaatg caaaagaatg aaaacgcgtc aaatcaacga tgtataaaag
    12961 atgcataaaa gataatgaaa gtaaaaagcc ataaatgccg tcatataggc atttatggct
    13021 ttttgtttgg ttaacataat cgatgattat cagaagttca attcacataa aaaagcacgg
    13081 ctaatttatg aacttgtcgt acctttttaa ttaaaattag ttaccaaata gacgactcca
    13141 aaaccccttt ttaggttccg tttcttcact cttttcttct atatcactat cattgtcatt
    13201 tggattagct gaaacgtctt ctctttgtgc ttcttcacct tgtgtacttt cgtcgctttg
    13261 acttccagat atatccttat attgaatctc tgtttcttta gtttcttcct gatctcggtt
    13321 aatatttaca ggactagtag tatatgtttt ttcttgtgca tcaacgtttt gtctagcgtt
    13381 agtagatgta tcaaagggat aattaaggtg tttttctttt tctaattgat tttctaattt
    13441 ttgaatcttt ttattactct ctaatgccag aacttgctga ttctcaagca attttgatct
    13501 ttcttgcaac tcttttctgt aaaattcaat tgttgtttca tgacgacttt cttgtttttc
    13561 aatttgatta tttaaagtat taatctgatt tttaagtatt tctactattt gagcatcgct
    13621 tttagattca aaattaatat tatccgactc ttttttttgt ttgtcttcag tagcactttc
    13681 aaaaccatat ttctttttat tttcatttac tctttgaatg attttttcta tatcggtatc
    13741 ttctttaata aacgaagtgt tttcctgttt tattgtctct atattcaatc tcttaatatt
    13801 attaaaaatc gtttgcttac taacccctaa ttcttcactc aaccttttta cacttttcat
    13861 atcatcaacc ctttataaaa tgtttataaa cccttagtaa aatattataa gcttataacg
    13921 attaataata aagtaatcga caaataaaaa tataaattcg ccaacctttt tatcaagggt
    13981 ttgtaaaggg tttatggtgt ttatcaaagg tttataaacc tatattttcc cttttttaag
    14041 tttattcaaa gtgctataat aaccttaata taacaaaaac cccaactact ggtaatagtc
    14101 ggggtttggt aataaaacgt ttagaaactg tttatttata taattttcga tacttagatt
    14161 atataatgaa taatatctta gtgcaagcac ctagattatt aaataaacac aaaaaatgta
    14221 agcgttttat tacctcttac caaactaaaa ttcggaaaga ggtttttatt atgtcaatta
    14281 aactttacaa cataaatgag gaatacagag aaaagtttta tcaaataccg aaagtatttt
    14341 ttacaaatcc taaatatatc aagttatcca atgatgcaaa aatggcatgg ggtattctta
    14401 gagatcgttt agatttatca attaaaaatg gttgggttga ttctaaaaca ggtaatattt
    14461 atttttatta caaaaatgaa aacccacaaa atatattaaa ttgtaaaaaa gataaagtaa
    14521 ttaaaataaa gaaagaactt aattgaagcc gaattactac tacaagaaag acaaggttta
    14581 aataagacaa ataaacttta tttagttaaa ccagaagtaa cagaagatga tatttataaa
    14641 attcaaaagc aagaaaacac tgttgagagc agcaatggca aggaagtcgg aaaaaccgac
    14701 ttcaagaagt cgataaaaca gaatctaatg atactgaact tagctatact gaatctaaca
    14761 atactgaaat aaatgatatg aatgacttga atgatataga gtccgaaaat gaaattagta
    14821 atcattcaag tcaatgcaag gttatttaat gcaaacaatt ttaactgaat ttgaagaaac
    14881 acatgcactt tatatgcgcc gtaaaaacat gaaacaatat aatatcttta atcaatcatt
    14941 caaatgattt tataacaatc aaagatacat caaaatattt cgttaaatca tctgactttt
    15001 taactgatag cgatgaaaaa atcaagaaat tgtcagtgat ctagaaaaag atttgtatcg
    15061 aaaacgtatg ttaagttatg gtggattgct taaataaaaa cataaaattt taaacttaga
    15121 cgatgctgaa gatggcaatt taattaatac aagtgatgaa gataaaatag caaatgaaga
    15181 agaaaaggca cattcgatta cggcaatttt gaaaagcaaa attattattt aaggcattag
    15241 tgataactga tgtctttttt tattactttt ttgtaaaaaa agtgctgtct tatttttgtg
    15301 acaaatgctg tatgtagtgt cacaaaagtg tgacacttga gctttttatg accccacaca
    15361 aaaacatttt cgaagccttg aaatatctgg ctttgccaga tcccccattc attgatgggg
    15421 acaaatttcc cttatgctct tacggagatt ttagagttaa attaaaattt ctaagttttt
    15481 gataagaaaa gccctgcagg aatttagaag aacgtgggga agttttaaag aattttatgc
    15541 taatttttaa tttgcatgta aatgggcagt gtctaaaaaa tagttattgt ttttgctcaa
    15601 atttttgttt ttgaaaatag catatattta tttggctcat atttgcgttt taaaagcgta
    15661 tataagtttt agatataaaa ctatatgaat cacccctaaa tctttaaaat gccctcttaa
    15721 aattcaaaat aagggcataa aaaataaaag cccccccaga taaagtgagg tagctttttc
    15781 tttcgacgcc gtatcgtcga tgtaattcaa aaaagttatg ggctataaat ctacatcact
    15841 ttttcaagaa tgtagtagca atattcaacg caaattaatt tttataactg ctcggaatat
    15901 ctcaagccgt ttctttaatt ttgaaataaa aaaaatcgac gaaggtcgat tacgtttttg
    15961 cacatgtcga tttatccgac gtataagtgc gcccttacgg gatttaacta gattataacg
    16021 acgaatttta gacctgtaaa gcaataacaa ttaggtctac caggtagata aagtgtacaa
    16081 agtagaaccg aaaaagttat ttattttgaa gatttttcgt agatataatt tgctaataaa
    16141 cttcctaaaa ctgaataaag aaaaatagtt aaactcatgt aatcactcca taattctgaa
    16201 gtgtctccat gtctacgcat agacacgcat ttatgccgag aaaatttatt gtgcgttgag
    16261 aagaaccctt aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc
    16321 attcgacaag ttttgggatt gttaagggtt ccgaggctca acgtcaataa agcaattgga
    16381 ataaagcacc tatgattatt taaaaatata agttataata cattcaaaaa tatttttgaa
    16441 tgaggtgtat tatgattcaa acggttgttg ctgctgctgt tctttatatt gctacagcag
    16501 ttgatttatt agtaatttta ttaatatttt ttgctagagc aaagactaga aaagaatata
    16561 gaaatattta tgttggtcaa tatttagggt ctattatttt aatattagtt agtttgtttt
    16621 tagcttttgt attaaattat gttccagaaa agtggatatt aggtttattg ggtttaatac
    16681 caatttatct tggaattaaa gtggctattt atgatgattg tgaaggagaa aagagagcta
    16741 aaaaagaatt gaatgaaaaa ggattgtcta aattagttgg tacggttgca attgttacga
    16801 tagcaagttg tggcgccgat aatattggtt tatttgttcc gtattttgtg acattaagtg
    16861 ttactaattt attacttact ctgtttgtct ttttaatttt aattttcttc ttggtgttta
    16921 ctgcacaaaa attagctaat atcccaggaa ttggagaaat tgttgagaaa tttagtcgtt
    16981 ggattatggc tatcatttat atagctttag gtttatttat tattattgaa aatgacacta
    17041 ttcaaacaat tttaggattt atattttaat ttagggtgtg attttatatg agttatgaaa
    17101 atacttgtga tgtgatctgt gtacatgagg ataaagttaa caatgcttta agttttttag
    17161 aagatgataa atctaagaaa ttacttaaca ttttagaaaa aatttgtgat gagaagaaat
    17221 tgaaaatcat attatctttg attaaagaag atgagttgtg tgtttgtgat atttctttga
    17281 tattgaaaat gagtgttgct tcaacttcac atcatttaag gcttttatat aaaaatgagg
    17341 tacttgattt ttataaagat ggaaagatgg catattattt tattaaagac gatgaaataa
    17401 gagagttttt ctctaaaaat caggagggtt tttgaaacga gtgaaacgag tttcttcttg
    17461 tcttgatact ataaaaaaca aagttatata acataagacg acttatcgga agttatctat
    17521 catcgtatat tcggagatga tataatatac aggtcgccta tctctcaggc gtcaattcag
    17581 acgcagagag gaggtgcatt actttgctaa tcattttcgt tcacatcata gcaccagtca
    17641 tcagtggctg tgctgttgcg tattatactt attggcttag taaacgcaac aaataattaa
    17701 taggcgactt tataagccag catcgaaaaa atccccacac tattgcagta gtgtggggat
    17761 tggtgcatta attgttaatc attttcgtta tctagattat aacactggtt agtagaggaa
    17821 tgcaaaaaga taatatttta agtagtcttt ttggatatta tcatatgata tatttatgta
    17881 aattgatttt ttattaaagg agcatatatg agtaatacta aaattaaata tcaaattttt
    17941 atttcatcaa cttatttaga tttaatagaa gagcgtcaag cagtagtaga agcagtttta
    18001 aacagtaata atattccagc aggtatggaa ctttttaact caagtagtaa aagccaatgg
    18061 gaaataataa cacaatggat caatgaatca gatgcagtga tattattgtt aggttctagt
    18121 tatggaacaa ttgatagtga agaaaatatt agctatacag aaatggagta caattttgct
    18181 aaatctttag gtaaacctat atatgttttt gagatgaata aagcatctac cgaatccgcg
    18241 gaaaagtcta aaaaattaga tgagtttaag acaaaagtta aagaaaatag actaattagt
    18301 ccaaatatta atgatatttc ggaattaaaa agtaaagtat ctcagacttt aatgcaaagt
    18361 gtacctagtg aaattaaaga aaatagtgga tggataagag tacaggattg tggtaaaaat
    18421 gtaaaaaatt taaaaaaatt ggatgctata caaagagatt tagatacata tgattttttg
    18481 aaagaagaac tttataaaat attcatgtat gtaaaaactt tttatttcca gcacacacca
    18541 tttgatgata gttatattga agatatagaa aactacctgc taaattatga aaataatcca
    18601 cataaatcat tcatgaaaat aaaagtttat gattataaaa actttttaaa acatttaaaa
    18661 aacatattga ttttaattaa acaaggaaaa aagccattag ctcaagccgg tcattttaaa
    18721 ttaagctttt acgaagagga tttaaaattg ttacaaaaaa attataagac tacgctagtc
    18781 gatattaaag gattgaataa acatttttat aaggaatgtg ataggtgctt aaaagcatat
    18841 aatattttta ttgagggtat aaataaacat ttatatgaat gatataagta caccctaatc
    18901 atacatatat aattgttgtc actttactcg atatatgaga atgactttac ctaataaatg
    18961 agaaaagcaa cgcactatat taaaatgcgt tgctttttct attatcgaat acctataact
    19021 aaactatctc tagctgtttc tacaacttct gtacttattt tatctaaacc atttatatcc
    19081 ataattctgt ctatctgcgc aaataaacga tgaatcagcc taaaattccc ttttgtaatt
    19141 ttaataatcg tcgttattgc ctcataatca gtaaagtctt cgagttttaa atcaaatcct
    19201 aagtcttgcc acttatattc taatatatga tgcgtctcat ctttacttag attatcaaat
    19261 tcatgcgcaa aacctatacg cgaatatagt tgaggataac gagatagttt tttctctata
    19321 cccggcatac caataaatat cattgctaaa ttatgttcat cataaatagc tcttaattgc
    19381 tctaaatgtt gcactttaag gcgatcaatc tcatctacta taattaaatc aatatattta
    19441 aacatatcac tataatgttt actatgttca tgtccatact tatttacaac atgtaatttt
    19501 tgacccaaat caatgattgc agtaatacta tataaatcat tccttaattt agtttgtttt
    19561 tctgctggtg cattataaaa tattttatcc accgatagta tgtcatcggt cgttttacta
    19621 gctaaatctt cccaacctct atggttaact tgtttttcaa tagtatccca atttgtgtaa
    19681 tacctagacg ataaagtttt tccgacacca ggttgaccat aacatatacc aatatactga
    19741 tatttaatac aagcatcaca aaattcagca aagcgtttat actctttcgt ttcaataaaa
    19801 ttttgatttt tagtcattac gatacctctt taattttttg acgtttttag tcgtttcttg
    19861 aggtgaataa ccacaatttt tttctttctt aattaattcc gtggtacttg gactagcaat
    19921 attttgtttt aagtgttttc ttctctgact acgagcgtgc tgtaagtctt ttatatctat
    19981 ggagtaatca gctatttctg gacatatagc agtacaaaga aattcatctc tataaaacac
    20041 acgtatttca gccatatcat ttgggttata acgaatcagt acatattcac ctacataagc
    20101 tgctagatta gtattactgt atcgaaaacc ttgaaaatga atgccatctg aatgaacttt
    20161 tctagattta ggtatttcca acaataataa atcaagttgt tctaagctac ttggcatatt
    20221 agggaaaaag tgattactat tccaacgact gataggcgtg gtatggatag tactatgttc
    20281 tttttgatta taatcttcaa ttaaaaagta acgtaatttt tcttcaaaat tgtgaaaatt
    20341 tattagatta ctaggagtat cattattgtt tatatatcca ggcagttgtt ctaagaaagt
    20401 ttgattaact gtctgaaaga atcgttctat ttttccacga ccacgaggaa caccaacttt
    20461 cgaaaacatc aagttaattt tcaaatcaat agcgacttgt tccatatgat gtgaagtaaa
    20521 gtcacttcca tgatctgtgt agaatttttc gggtatacca cacactggcc aattggtatc
    20581 atttttattc catattgctt ggtgtagtgt taatgctgtg ttttgagcat tgggggcatc
    20641 aaaacttaag aaatagcctg caattgcacg actatagtca tccataataa tagttagcca
    20701 tggtctattg atattacctt tttggtctaa
//
