LOCUS       NZ_CP118983            28553 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus equorum strain DSM 20674 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP118983
VERSION     NZ_CP118983.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN33336506
            Assembly: GCF_029024965.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus equorum
  ORGANISM  Staphylococcus equorum
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28553)
  AUTHORS   Romano',A., Ivanovic,I., Segessemann,T., Vazquez Rojo,L., Dreier,M.,
            Sesso,L., Vaccani,M., Schuler,M., Frei,D., Frey,J.E., Ahrens,C.H.,
            Steiner,A. and Graber,H.U.
  TITLE     Elucidation of the Bovine Intramammary Bacteriome and Resistome from
            healthy cows of Swiss dairy farms in the Canton Tessin
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28553)
  AUTHORS   Romano',A., Ivanovic,I., Segessemann,T., Vazquez Rojo,L., Dreier,M.,
            Sesso,L., Vaccani,M., Schuler,M., Frei,D., Frey,J.E., Ahrens,C.H.,
            Steiner,A. and Graber,H.U.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2023) Food Microbial Systems, Agroscope,
            Schwarzenburgstrasse 161, Liebefeld 3097, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-MAY-2021
            Assembly Method                   :: Flye v. v2.8.1-b1676
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 5351x
            Sequencing Technology :: Oxford Nanopore + Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029024965.1-RS_2024_03_30
            Annotation Date                   :: 03/30/2024 07:42:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,664
            CDSs (total)                      :: 2,578
            Genes (coding)                    :: 2,548
            CDSs (with protein)               :: 2,548
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 16 of 30
            Pseudo Genes (incomplete)         :: 11 of 30
            Pseudo Genes (internal stop)      :: 10 of 30
            Pseudo Genes (multiple problems)  :: 6 of 30
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118983.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28553
                     /organism="Staphylococcus equorum"
                     /mol_type="genomic DNA"
                     /strain="DSM 20674"
                     /isolation_source="Skin of horse"
                     /host="Horse"
                     /culture_collection="DSM:20674"
                     /type_material="type strain of Staphylococcus equorum"
                     /db_xref="taxon:246432"
                     /plasmid="unnamed1"
                     /collection_date="1984"
     gene            1..591
                     /locus_tag="PYW44_RS13120"
     CDS             1..591
                     /locus_tag="PYW44_RS13120"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002468647.1"
                     /GO_function="GO:0019172 - glyoxalase III activity
                     [Evidence IEA]; GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family protein"
                     /protein_id="WP_107517807.1"
                     /translation="MKNALFLLLDEFADWEGSYLSSTLNQSESWSVKTISVEEKVVSLG
                     GFSVLVDYVIGSEPKDYDLLIMIGGNSWDNSSDDLLRFVQETFNKGIPVGAICGAVDYL
                     AKNGFLNNYKHTGNSICLWSDYDCYTSANKFIEKQAVKDGKTVTANGTAPLEFTELVLK
                     LIEFDAPENIEKTMFINRHGFYNYCEKYGNPFL"
                     /name="type 1 glutamine amidotransferase family protein"
     gene            1360..1461
                     /locus_tag="PYW44_RS13125"
     CDS             1360..1461
                     /locus_tag="PYW44_RS13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_002495781.1"
                     /translation="MLDNFVHITTTAASGCIVALFAHWLRNRNDKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            1679..1876
                     /locus_tag="PYW44_RS13130"
     CDS             1679..1876
                     /locus_tag="PYW44_RS13130"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071561892.1"
                     /translation="MLNYSDQQYAIIKSVLGENAYNRLIEDIEGVVKDKTNSISIKIPD
                     GGDFLFINTDSIAFINIDKQ"
                     /name="hypothetical protein"
     gene            1935..2810
                     /locus_tag="PYW44_RS13135"
     CDS             1935..2810
                     /locus_tag="PYW44_RS13135"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_107377005.1"
                     /translation="MKNNFSKHIILDKLNFNRMHKNIEDINSIFSKKISEAIKDINSKY
                     SKKISESIEVLAKSIPNLDEFKDALDSFIDNTTTVNSIFINYDYPPIDYVDINEVINYV
                     EMNSNHQEVTKENINLIMTRYFDEIHFNHLKSQVTTYKLPQEDITILKEILDGYKHEYY
                     YLIIPALLARLEGMIFNSVNYKGRTNYRLFNIVIEETINKYKSKHDYYVDADYVKIKEY
                     YKFKLKRNFEFGEKRMNEINRHSIMHGYDNQYGTKQNAVILLLHFEYLYHCLAELNEND
                     KQDIRNKMLK"
                     /name="hypothetical protein"
     gene            2954..3991
                     /locus_tag="PYW44_RS13140"
     CDS             2954..3991
                     /locus_tag="PYW44_RS13140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019236158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="WP_107377004.1"
                     /translation="MKAAVWYGQKDVRVEDRKSKELQDNEVKVKVSWAGICGTDLHEYL
                     EGPIFISTDKPDPFLGQKAPVTLGHEFAGVVDDIGSKVTKFNKGDRVVINPTVSNREKE
                     ENIDLYDGYSFIGLGSDGGFAEFTNAPEENVYKLPDNVSDKEGALVEPTAVAVQAIKEG
                     EVLFGDTVAIFGAGPIGLLTTIAAKAAGASKIFVFDLSEERLNKAKSVGATHTINSGES
                     NPSDIISKYTDNGVDVAFEVAGVAPTLKSAIDVTKARGTVVIVSIFGHPIEWNPMQLTN
                     TGVKLTSTIAYTPTTFQQTIDLINEGNLKVKDVVTDEIELDDIVESGFKQLVNDKSQAK
                     ILVKL"
                     /name="2,3-butanediol dehydrogenase"
     gene            complement(4115..4489)
                     /locus_tag="PYW44_RS13145"
     CDS             complement(4115..4489)
                     /locus_tag="PYW44_RS13145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002508680.1"
                     /translation="MINEMEELNQIKLDLKKLRNEFPSMYEKLEYIASLTRQLSIHYKY
                     LGALMFSDNRENIQNERPILIRESVLKLYEQEVAKVKKDSDFVFFKDMMLKFQNVDYSQ
                     IFLIILGAEPGFVFNNTIIK"
                     /name="hypothetical protein"
     gene            complement(4497..5021)
                     /locus_tag="PYW44_RS13150"
     CDS             complement(4497..5021)
                     /locus_tag="PYW44_RS13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011304038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_002508681.1"
                     /translation="MENYKFPSDSKIVSTDQVLINDLNNYNTLFGGVLMKKIDNNATLS
                     ARRHARVKECVTASTDSVEFLYPITQSDSVCIESYVVYTGEKSMEIFCKVISEDMITAE
                     RKIAAVAFLTFVALDEKKKPIKIPKISPQSKEEKLLFMDGEARAKMRKIKRSQTKNIID
                     SLDINKPWELE"
                     /name="acyl-CoA thioesterase"
     gene            complement(5132..>5455)
                     /locus_tag="PYW44_RS13155"
                     /pseudo=""
     CDS             complement(5132..>5455)
                     /locus_tag="PYW44_RS13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467786.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing protein"
                     /name="LysR substrate-binding domain-containing protein"
     gene            complement(5519..6070)
                     /locus_tag="PYW44_RS13160"
     CDS             complement(5519..6070)
                     /locus_tag="PYW44_RS13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508682.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002512562.1"
                     /translation="MAKIGYARVSTQDQSLDGQIDTLEEYGCERIFREKASGRKTKRTE
                     LDKCLDYLREGDILVIYKLDRLGRTTKQLIELSQWFDENSIDLHIIDMNVSTKDAMGKM
                     FFTMMSAFAELEANLLSERTKKGLEAARARGRKGGRPSLPDHKKREIKFLYDEQKLTGE
                     EIAKQTGVSRSTVYRIIKNN"
                     /name="recombinase family protein"
     gene            complement(6324..7139)
                     /locus_tag="PYW44_RS13165"
     CDS             complement(6324..7139)
                     /locus_tag="PYW44_RS13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164963.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWNTIEKQVNHRGWEDLASKTTDDILSVNKIFYTAPAEKQTRLSNDLYSISASIDL
                     GQKLHIVNKYGHDHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(7132..8574)
                     /locus_tag="PYW44_RS13170"
     CDS             complement(7132..8574)
                     /locus_tag="PYW44_RS13170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790705.1"
                     /translation="MKNKEKYLTNFSEAKRKEATQKYNIIKPFILGKQSLSSISKSKGI
                     ALSTLYRWNKLYKEQGLTGLIHNTRVDKGEHKLKQNIIDEIKRLALKNKRNSIATIHRK
                     IANYCIENNFYKPSYKQVYSIIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIYILDQKGNINRPWLTIIMDDYSRAIAGYFISFDAPNAQNTALTLHQAIWN
                     KNNTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTSSDLIDFQNFEEKLRYFLIEDYNQKEHSAIQSTPINRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKIHSDGIHFQGFRYSNTNLTAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAISPDLADYSIDIKEIQHARSQRRKHLKQNIASPSTTDLIKEEK
                     SYGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(8546..9139)
                     /locus_tag="PYW44_RS13175"
     CDS             complement(8546..9139)
                     /locus_tag="PYW44_RS13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690628.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNAYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEEKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(9403..9783)
                     /gene="blaI"
                     /locus_tag="PYW44_RS13180"
     ARG             complement(9407..9783)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9773..11530)
                     /gene="blaR1"
                     /locus_tag="PYW44_RS13185"
     ARG             complement(9777..11530)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.83"
                     /coverage="100.0"
     gene            11637..12482
                     /locus_tag="PYW44_RS13190"
     CDS             11637..12482
                     /locus_tag="PYW44_RS13190"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
                     /protein_id="WP_000733283.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
     gene            complement(12848..13060)
                     /locus_tag="PYW44_RS13195"
     CDS             complement(12848..13060)
                     /locus_tag="PYW44_RS13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069820938.1"
                     /translation="MKVKDQQPYILDNEQGSREEVEVREQRIKELEEDDEQEDKNQNNK
                     IIIFTTILIFILTIILSVIIQTNKK"
                     /name="hypothetical protein"
     gene            complement(13139..13438)
                     /locus_tag="PYW44_RS13200"
     CDS             complement(13139..13438)
                     /locus_tag="PYW44_RS13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002508712.1"
                     /translation="MVNSDKKEIEISKTNETRSNEISKMIEEGGLGADQYYTIDKQQPN
                     QKILIENIDQFKDEISQKDNDDLIDLLILNAQENINSKGNHALIIIKKELLSRM"
                     /name="hypothetical protein"
     gene            complement(13742..15202)
                     /locus_tag="PYW44_RS13205"
     CDS             complement(13742..15202)
                     /locus_tag="PYW44_RS13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019375671.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="WP_069828349.1"
                     /translation="MNNNKHQKYEYLADDPNFKTLPIILSLIIGAFFAILNETLLNIAL
                     TSLMKEFDITLPTVQWMTTGFMLIMGIVAPISALLLQWFTTRQLFLSTMTIFTLGTVIC
                     AAAPAFPILLIGRFIQAIGTGMLLPIIFNVFLLIYPPFKRGKIMGIVGFVIMFAPTIGP
                     TLSGVIVEYLGWRSLFIMVIPFSIFSIAFASKFLINVSEVTKPKIDYLSLVFSTIGFGA
                     VIYGFSSAGKSESGFLSINVLIPIIVGIIGIVLFSIRQLNLKEPLIDLRVFKYPMYTHA
                     ILMFLIIIMTMFASEIILPIYMQGPLALTAATAGLILLPGSLLNGAMSPFMGYLFDKFG
                     PRVLMIPASIVLSGAMYVMSRLNVDTPLWIVILSYILLMLSVSAIMMPAETNGLNQLPK
                     HLYPHGTAVMTTLQPVAGAIGVAVFVSIMNARQLQFLQNSGKPQDPDTINQAMVAGVEL
                     VYFISFSISIIAVILSFIVYRATPKKTD"
                     /name="MDR family MFS transporter"
     gene            complement(15524..16423)
                     /locus_tag="PYW44_RS13210"
     CDS             complement(15524..16423)
                     /locus_tag="PYW44_RS13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(16765..18231)
                     /gene="msr(A)"
                     /locus_tag="PYW44_RS13215"
     ARG             complement(16769..18231)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.18"
                     /coverage="100.0"
     gene            18650..19231
                     /locus_tag="PYW44_RS13220"
     CDS             18650..19231
                     /locus_tag="PYW44_RS13220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_107517820.1"
                     /translation="MPKIINHKEKKKQIIQYAFDSIVENGAKGSTVRQIAKLAKMTPGQ
                     IRYYFPNHSELLNAVMSAIELKVRRKIEVIFTSEDLNAIDKAKVSLLTVLPLDQERLAD
                     MEVWMAFRYDIHEYGQSTLDDGLDQLCHSVLTLLSNDHLLKDNLNIHLHSMKLHALIDG
                     LALHKLLNPNQTSNEDIQSIVDEEITRLTQ"
                     /name="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
     gene            19245..19793
                     /locus_tag="PYW44_RS13225"
     CDS             19245..19793
                     /locus_tag="PYW44_RS13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069819292.1"
                     /translation="MNFIVWLIIFCEVAFWVVILLGLVTRYILKQKTLGLLFLALTPVI
                     DLIILITTSIDLMNGATAEIPHAIAAVYISVSLVFGKSMINWADDRFRYYVMKQGSKPY
                     KAVGLAYAKNYAKSWLKHLLSYIIGTGILHLIVFLINDKSRTEAIDNVIHVWTIVIIID
                     LIICISYFLWPPKKKVNHN"
                     /name="hypothetical protein"
     gene            complement(19947..21554)
                     /locus_tag="PYW44_RS13230"
     CDS             complement(19947..21554)
                     /locus_tag="PYW44_RS13230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017795875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="WP_069819293.1"
                     /translation="MHEKFSGWNTLFLHYLKLDWKKMIIWILSIGLFSAGFVPAFKEIA
                     QGKGLIGMFETLQNPAMISMVGPTPIETATDYTLGAMYAHEMLLFCGLFAMIVSILHII
                     GHTRKEEELGLTELVRSFQIGRQANSLATIIEIVLINGLIAMFISAVMVSFNAETISLQ
                     GALLFGITIGMAGVMGASIALVVSQIMPTSSSAIGLSLGIVGLLYIIRAGTDVSNIELS
                     IFNPLGWTYLTYPFTDNNWLPIAIAFIFSIIVVIIAFMLEGARDMGDSYIPEKKGKRNA
                     KKSLLSIRGLLCKINQSIIISWLVAFMVMGIAYGSIYGDMQTFLESNEMMKQMFSTSNV
                     SIETSFTSTIMVVMVSLVAILPIVIVNKLFSEENKLHLSQIYPTKVTRSRIYWTNIGLA
                     FFSSVLGVLVASLSLGVTAINVMEGHGEMQLIDFLAAGYNFLPAILFFTSLATLAFGWA
                     PKLGKIAYAYLGYTFALNYFGGTLDLPEWLSKTAILNWLPQMPKENFDIFSFVILSMIS
                     IVFIILGYIGYKKRDLIG"
                     /name="tetronasin resistance protein"
     gene            complement(21580..22461)
                     /locus_tag="PYW44_RS13235"
     CDS             complement(21580..22461)
                     /locus_tag="PYW44_RS13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343783.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_056935283.1"
                     /translation="MREVVKITGLQKNFGDFKALNDVSFTVNKGEVLGFIGPNGAGKST
                     TLRTLLGVIKRDAGEVEIFGKDVWKESLKIHKRISYVPGDIALWGNLTGGEIIDLFMKL
                     HGSGDTEKRDELIKRFELDPKKKSKGYSKGNRQKVGLIAALSVDSDLYIFDEPTSGLDP
                     LMEVTFQEEVEKIKATGKSILLSSHILSEVERLADRVAIIRQGEIVETGTLDELRHLTR
                     STLMIETEEDVAKLSEIQGVFDFKQSNNQATFSADNKHLNSILSEAVKLGVKKLESTPP
                     TLEDLFIRHYEG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(22513..23112)
                     /locus_tag="PYW44_RS13240"
     CDS             complement(22513..23112)
                     /locus_tag="PYW44_RS13240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528983.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_236593618.1"
                     /translation="MKTNKQKMIINSSIKEFVKNGFDKASTNEIVKKANISKGSLFNYF
                     NSKKDLYIYLINYSTQILENMYREIDLSEKDLFNRIENIGLQKLYVQQKHPEIFDFLKH
                     SIQEESLEVKAIIEKKVDHIYENGRQKIFANIDYSKFRDDIDIEKAIEILNWTMSGFGE
                     KGLQQIKSFENISDFGNQYLKEWHDYAQILKNSFYK"
                     /name="TetR/AcrR family transcriptional regulator"
     gene            complement(23316..23990)
                     /locus_tag="PYW44_RS13245"
     CDS             complement(23316..23990)
                     /locus_tag="PYW44_RS13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_115076074.1"
                     /translation="MKSVKMLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINVESKSDTQIVEILKNQIDTLNDQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEEERHLNYSFDTSTNDR
                     QNVDAQEATYTTDSVNINQHQEEEKEAEIQHKDIDESKSDESTRYEETQPKKGFWSRLF
                     GG"
                     /name="DUF536 domain-containing protein"
     gene            24409..25380
                     /locus_tag="PYW44_RS13250"
     CDS             24409..25380
                     /locus_tag="PYW44_RS13250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_115076075.1"
                     /translation="MSRKNIKNQASQNFYMLHKVLFINEKYKKLSDSAKVTYAILNDRV
                     SLSIKNNWIDQNGDIYFIFTNENLQEVLDKSKNTITKIKKELQEVGLLEQVKTGFNRPN
                     KLYLHEIETNINIEKEIQNSTSNNDESSDSKESQIMGVQNPKQWEPRIPNNGSPESQNL
                     DSNDTDLSNTDYIETENNDTNDLNDTYNNPINNNHSDHTNHQQTEFNNDALKFQVLEEL
                     PQQLQDYLSKFEIREIRIIKSVLLKGKKSFNNAHDTYYRLEDVEFEIVSVLKRFKAMLL
                     QKNETVEAMQGYLMQSIKAEFEETHALYMRRQNMKQHNIFNQ"
                     /name="replication initiator protein A"
     gene            25555..25983
                     /locus_tag="PYW44_RS13255"
     CDS             25555..25983
                     /locus_tag="PYW44_RS13255"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_236593617.1"
                     /translation="MTQYQTWGPQSYEETQQFINVVLDKESNWIYNVLVDPDTDKVIGA
                     IQLAIDEVNQSAEINFIVHPNYWGDGVATDIAKTIIKYAFKVLKLNRIGAAIDSNNIAS
                     GIVLEKLGMKREGMLRKDKLVQDEYRDTLIYGLLRSEY"
                     /name="GNAT family protein"
     gene            26868..27416
                     /locus_tag="PYW44_RS13260"
     CDS             26868..27416
                     /locus_tag="PYW44_RS13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_107517809.1"
                     /translation="MNSKFKVFLYDLFISFLVTLIINFSVYFFSLKSISFDFLIKYKFY
                     FYWFVLFLFVLVIRFFIKKYIDRLQDDIPRIVMASYNKWFVKTDYLGFTWTVLFNFLSE
                     NWKNLDLQKCKFEDLEEVEICDVKGPYCPDDKREMKVTRTYFGRYKYKCPKCKYKKKLL
                     KNHITLVNDTIDEFRSKFR"
                     /name="hypothetical protein"
     gene            28159..28365
                     /locus_tag="PYW44_RS13265"
     CDS             28159..28365
                     /locus_tag="PYW44_RS13265"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_069813475.1"
                     /translation="MPSLFFFVAQVVAPIYSVVAHHVVPIYGVVAHIVQHSKNKKIVLF
                     ASINEWITYMFIWNFFFNNFNKV"
                     /name="hypothetical protein"
     gene            <28426..28539
                     /locus_tag="PYW44_RS13270"
                     /pseudo=""
     CDS             <28426..28539
                     /locus_tag="PYW44_RS13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832602.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4260 family protein"
                     /name="DUF4260 family protein"
     ARG             complement(15528..16423)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             11638..12479
                     /name="blaPC1"
                     /gene="blaPC1"
                     /gene_name="BlaZ family penicillin-hydrolyzing class A
                     beta-lactamase PC1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(16766..18231)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.77"
                     /coverage="100.0"
     ARG             complement(15525..16423)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             11638..12482
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.09"
                     /coverage="100.0"
     Typing          complement(23356..23990)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.138"
                     /coverage="85.0"
                     /evalue="0.0"
ORIGIN
        1 atgaaaaatg ctttatttct tttgttagat gagtttgcag attgggaagg ttcttattta
       61 tcttcgactt taaaccagag cgaatcttgg tcagttaaaa ctatttcagt tgaagaaaaa
      121 gttgtttctt taggcggttt ttcagttttg gttgattacg ttattggttc tgaacctaaa
      181 gattatgatc ttttgataat gattggtggt aattcttggg ataacagtag tgatgacctt
      241 ttaagatttg tccaagaaac ttttaataaa gggattccag taggcgctat atgtggtgct
      301 gttgattacc tagcaaaaaa tggatttttg aataattata aacacactgg aaattctatt
      361 tgtttatgga gtgattatga ttgttataca tcggcgaata aatttataga aaagcaagca
      421 gtgaaagatg ggaaaacagt tactgcaaat ggtacagctc cacttgaatt tactgaatta
      481 gttttaaaac taattgaatt tgacgctcct gaaaatattg aaaaaacgat gtttataaac
      541 aggcatggtt tttataatta ttgtgagaaa tatgggaatc catttttata aagaaattaa
      601 gaattttagc actaagtaat tatagcaacc atcattttgg ttgcttatat attattgttt
      661 taaactccct ttaatatttt tgattagtgt catatttgca tacacttatt ttgatttcag
      721 tgacataaat aacttaataa aatagaactt aaaggtacaa actaacttat gtttatgaac
      781 cattaaagtg taggggaatc ttttgggatt cctagacaac aggataaggg tgaacaatgc
      841 catttacatg gcacctagca tagctagggt tttgaatact taattttaag ttccataaat
      901 actactatga caacacttat agtaaattaa ggacaaaaat aaatcgaaaa agtaaagtgt
      961 cattaactgg cattatgaaa ctgttcacga ttttctataa aagctgttgt aaaggtattt
     1021 ataggggatg ggaatcttta gaatcccgga ggaatcccaa aagattcctt tttatagcaa
     1081 ttttttgtat cttttcaatc ttgatatttt ttattaacgt taattttaaa taacttaatt
     1141 cgaaattttc aaatctaaaa acgagatttg taattaaata ttaaattata attatgattt
     1201 tcaaactttt tatattagca atttgtatta ttagtttgga gttttaatta acatagttca
     1261 acttatcgga agtatatatg cttacatgtt tacagatgat ataattatag agtcgcctat
     1321 ctctcaggcg tcaagttgac gtagagagga ggtgtaatta tgcttgataa ctttgttcac
     1381 atcacgacca cggcagcgag tggttgtatc gtagcgttat ttgcgcattg gctacgcaat
     1441 cgcaacgata agaaaaaata ggcgaccttt agccaacacc taaaaaatcc cctcactact
     1501 tccgatagtg aggggattgg tgtattatgc ttaataactt tgttaagtgc attataacat
     1561 cataattggt aggaatgcaa agtgattaaa ttagcagaag agtatactat attaaaaaaa
     1621 tccaaaattg gaggtaggta agctgtgagt acatatgaag aagaaagaat aacaataggt
     1681 gttaaattat agtgaccagc aatatgcgat tataaaaagt gtattaggtg aaaatgctta
     1741 taataggctc attgaagata tagaaggagt agtcaaagat aaaacaaata gcatttctat
     1801 aaaaattccg gatggcggcg atttcttatt tataaatact gattctatag cttttataaa
     1861 tattgataaa caataattta aaataaaaaa gttaacgata acggtcatta tgtaaattaa
     1921 gaagggaaat taaaatgaag aataatttta gtaaacatat catactagat aaattaaatt
     1981 ttaatagaat gcataaaaat atagaagata taaattctat atttagcaag aaaatatccg
     2041 aagcaataaa agatataaat tctaaataca gtaagaaaat atctgaatca atagaagttt
     2101 tagctaaaag tatacctaac ttagatgaat ttaaagatgc tttagatagt tttattgata
     2161 atacaactac agtaaattca atttttatta actatgatta tccgccaata gattatgtag
     2221 atataaatga agttattaat tatgttgaaa tgaattcaaa tcatcaggag gtaactaaag
     2281 aaaatattaa tttgataatg acaaggtatt ttgatgaaat tcattttaat catttaaaaa
     2341 gccaagtaac cacttacaaa ctacctcaag aagatattac tatattaaaa gagattttag
     2401 atggatataa gcatgaatat tattatctta taatacctgc attattagca agattagaag
     2461 gtatgatatt caattcagtg aattataaag gaagaactaa ttatcgactc tttaatattg
     2521 taattgagga aacgataaac aagtacaaat ctaagcatga ttattatgtt gatgctgatt
     2581 acgtcaaaat caaagaatat tataaattta aattaaaacg aaattttgaa tttggtgaaa
     2641 aaaggatgaa tgaaattaat agacattcta ttatgcatgg ttatgataat cagtatggaa
     2701 caaaacaaaa tgcagtaata ttattgctac atttcgagta tctttatcat tgtttagcag
     2761 aattaaatga aaatgataaa caagatattc gtaataaaat gttgaaatag taaactaatt
     2821 caatatttta catgattagg gtacactcta atcatataat aatttagaaa cactatatta
     2881 aaaggttagt ttacttgaaa gtaattttta aaaggcatac tattaaatta actaaaacaa
     2941 ggaggtttta tcaatgaaag cagcagtttg gtatggtcaa aaggatgtac gagttgaaga
     3001 tcgaaaatct aaagagttac aagataatga ggttaaagtt aaagtgtctt gggctggcat
     3061 ttgtggtaca gatctacatg aatacttaga aggccctata tttatttcaa cagacaaacc
     3121 agacccgttc cttggccaaa aagcgcccgt tacattaggc cacgaatttg caggcgtagt
     3181 agatgatatt ggttctaagg ttacaaaatt taacaaaggc gatcgtgttg ttattaatcc
     3241 tacagtttca aatcgtgaaa aagaagaaaa tattgacctt tatgatggtt attcatttat
     3301 aggcttaggt tctgatggtg gatttgcaga atttacaaac gccccagaag agaatgttta
     3361 taaattacca gataatgttt ctgataaaga aggcgccctt gtagaaccga cggctgttgc
     3421 agttcaagca attaaagaag gcgaagttct atttggcgat actgttgcta tttttggagc
     3481 agggccaatc ggtttattaa caactatagc agccaaagca gctggtgcta gcaaaatatt
     3541 tgttttcgat ttatcggaag agcgacttaa taaagctaaa tcagtaggtg ctactcatac
     3601 gataaattct ggtgaatcaa acccaagtga tattattagt aaatacactg ataatggcgt
     3661 tgatgtagca tttgaggtag ctggtgtagc gccaacactt aaatctgcta tagacgttac
     3721 taaagcaaga ggtactgtcg ttatagtgtc tatatttggt catcctattg aatggaatcc
     3781 aatgcaatta acaaatacag gtgtaaagct cacttcgaca attgcttata cacctactac
     3841 atttcaacaa acaatagatt taattaacga aggtaattta aaagttaaag atgtcgttac
     3901 tgatgagata gagttagatg atattgtgga gtcaggattt aaacaacttg taaacgataa
     3961 atcacaagca aaaattctcg ttaagttata aaagctaata aaagagccaa tctaaatcag
     4021 agtggctctt ttattagcta aaatatagtt ttatttagtc aagtgatttt taaattttta
     4081 taatttgtta atctaagcat tcttaatgaa cttattattt aataattgta ttattaaata
     4141 caaaaccagg ttcagcacct aaaatgataa gaaatatttg tgagtagtcc acattttgga
     4201 attttaacat catatcttta aaaaacacaa aatcactatc ttttttaact tttgctactt
     4261 cttgttcata taattttaaa acagattctc ttattaaaat tggtctctca ttttgaatat
     4321 tttcacggtt atctgaaaac ataagtgctc ctaaatattt ataatggata cttaattgtc
     4381 ttgtcaaact agctatatat tctaactttt catacatact aggaaattcg tttcttagtt
     4441 ttttcaaatc taacttaatt tggtttaatt cttccatttc attaatcatt ttatcactac
     4501 tccaattccc atggcttatt gatatcaaga gagtcaatta tatttttagt ttgtgatctt
     4561 ttaatttttc gcattttagc tcttgcttcg ccatccataa ataataattt ttcttctttg
     4621 gactgaggag agattttggg tattttaatt ggttttttct tttcatccaa agctacaaaa
     4681 gtaagaaaag ctacagcagc aatttttctt tctgcagtaa tcatatcttc tgaaatgact
     4741 ttacaaaata tttccataga tttttctcct gtataaacta cataagattc tatacaaact
     4801 gaatcagatt gggtgattgg atataaaaat tctactgaat ctgtagaagc tgtaacacat
     4861 tctttaactc ttgcatgtct tctagctgat agtgtggcgt tattatcaat ttttttcatt
     4921 aacacccccc caaatagtgt attataattg tttaaatcat taattaatac ttggtccgta
     4981 ctgacaattt tactatcact aggaaattta taattttcca taaaaaactc ccgtttctat
     5041 aatgttttac gttctaatta tagagcgaga gtgtataaat ataaaatatc ctttttttat
     5101 atagctataa atttctcaaa tgcttttata tttaatagtt aattaagaat ttttcttgga
     5161 gaaatttaat ccaatttttt gttaaagaat caactataat atcttttctc caaataatag
     5221 taagttccca tttcatggaa ggtttattaa tatcgatgac ttgtaaatta ttatctaata
     5281 agtctagtat tccttcgggt aatatacata tccctagatt atttaataat atttcttctg
     5341 tgaagctcca ttgagtggtt ttaaaaatca tattaggatt aaagccataa tttctacatg
     5401 tatttttgat tttatggttt aaacagaaat cagaattaaa taaaataaat tcttgttctt
     5461 ctaaaaaaga gaatttatta aagtttttat tatttcttca cgttaccagt tgtttaaact
     5521 aattattttt tattattctg tataccgttg aacgacttac accagtttgc ttagcaattt
     5581 cttctcctgt aagtttttgt tcatcgtata gaaacttaat ttctcttttc ttatggtcag
     5641 gtaatgaagg cctcccgcct tttcgccctc ttgctcgtgc tgcttctaat ccttttttcg
     5701 tacgttcact taataagtta gcttcaagtt cagcaaatgc actcatcatg gtaaagaaca
     5761 ttttacccat tgcatctttg gtcgatacat tcatatcaat aatatgtaaa tcaatgctgt
     5821 tttcatcgaa ccattgagat aactcaatta attgtttcgt tgtacgtcca agacgatcta
     5881 gtttatagat aactagaata tctccttctc gtaaataatc caaacactta tcaagttccg
     5941 ttcttttcgt tttgcgacca ctcgctttct ctctgaagat acgttcacaa ccatattcct
     6001 caagtgtatc aatctgtcca tcaagacttt gatcttgtgt tgatacacgt gcataaccaa
     6061 ttttagccat ttaaatacca cctcttttaa tcgttttatg ggtacttatt aacgaaatct
     6121 aattctcgat gcaaataagc gcgtctctca tcgtctgaaa actcataatt ttcgagaatt
     6181 atgatacatt gattataaca caagtttata gacttaaata tccaagaaaa acctcttatg
     6241 ttactttact tgatatatga gaatgatttt acctagtaaa tgagaaaagc aatgtcctat
     6301 attaaagtac attgcttttt ctattaacga atacctatga ctaaactatc tctagctgtt
     6361 tctacaactt ctgtactgat tttatctaag ccatttatat ccataattct atctatctgc
     6421 gcaaataaac gatgaatcag cctaaaattc ccttttgtaa ttttaataat cgtcgttatt
     6481 gcctcataat cagtaaaatc ttcgagtttt agatcaaatc ctaaatcttg ccacttatat
     6541 tctaatatat gatgcgtctc gtctttactt agattatcaa attcatgtgc aaaacctata
     6601 cgcgaatata gttgaggata acgagatagt tttttctcta tacctggcat accaataaat
     6661 atcattgcta aattatgttc atcataaata gctcttaatt gctctaaatg ttgcacttta
     6721 aggcgatcaa tctcatctac tataattaaa tcaatatatt taaacatatc actataatgt
     6781 ttactatgat catgaccata cttatttacg atgtgtaatt tttgacccaa atcaatactt
     6841 gcactaatac tatatagatc attacttaat cttgtttgtt tttcagccgg tgcagtataa
     6901 aatatcttat tcaccgataa tatatcatca gtcgttttac tagctagatc ttcccaccct
     6961 ctatgattaa cttgcttttc aatagtattc caatttgtgt aatacctaga agataaagtt
     7021 tttccgacac caggttgacc atagcagatc ccaatatatt gatatttgat acaagcatcg
     7081 caaaattcag caaatcgttt atactctttc gtttcaatga aattctgatt tttagtcatt
     7141 acgatacctc tttaattttt tgacgttttt ggtcgtttct tgaggtgagt aaccataact
     7201 tttttcttcc ttaattaaat cagtggtgct tggactagca atgttttgtt ttaagtgttt
     7261 tcttctctga ctacgtgcgt gttgtatctc ttttatatca attgaataat cagctaaatc
     7321 aggggatatt gctgtacaaa gaaattcatc tctataaaaa acgcgtattt cagccatatc
     7381 attgggattg taacgaatta atacatactc acctacataa gcagttaggt ttgtattact
     7441 gtatctaaag ccttgaaaat gaataccatc tgaatgaatt tttctagatt taggtatttc
     7501 taataataat aaatcaagtt gttctaaact gcttggcata ttaggaaaaa aatgattact
     7561 gttccaccga ttgataggag tgctctggat agcactgtgc tctttttgat tataatcttc
     7621 aattaaaaag tatcgtaatt tttcttcgaa attttgaaaa tctattaaat cgctagaagt
     7681 atcattattg tttatatatc caggaagttg ttctaagaaa gtttggttaa ctgtctgaaa
     7741 aaaccgttct attttcccgc gaccacgagg gacaccaact tttgaaaaca tcaagttaat
     7801 tttcaaatca atagcgactt gttccatgtg gtgcgaggta aagtcactcc cgtgatctgt
     7861 gtagaatttt tcgggtatac cacatactgg ccaattggta ttattcttat tccatattgc
     7921 ttggtgtagt gttaatgctg tgttttgagc attaggagca tcaaaactta taaagtagcc
     7981 tgcaattgca cgactatagt catccataat aatggttagc catggtctat tgatattacc
     8041 tttttgatct aatatataaa tatctagcaa agtatggtcg gcttgccata tttcattggg
     8101 tcttgaggat tctcttattt gtattaaatc gtacttattt tgatagtatt tttcaccttg
     8161 gtgagagaaa tcaataacag acttaggcat tgctttaata atactataaa cttgtttata
     8221 acttggttta taaaaattat tctctataca ataattagcg attttcctat gaatcgtagc
     8281 aatactattt cttttattct tgagtgcaag gcgtttaatc tcgtctatta tgttttgttt
     8341 taatttatgc tcacctttat caactcttgt attatgaatt agaccagtaa gaccttgttc
     8401 cttatataat ttattccacc tataaagtgt acttaacgca atacctttgc ttttagaaat
     8461 gcttgataaa gattgcttgc ccaagataaa aggttttata atattgtact tttgagtagc
     8521 ttctttacgt ttggcttcag aaaaattagt tagatacttc tccttgtttt tcatcttcct
     8581 tttcctccaa tttattgagg taacgataaa tcgttgtacg tgaaacttgc cactgctctg
     8641 caattgtctt aattggcgtg ccattatcat aaagtgtctt aagtaagttt aaatcttttt
     8701 gatttaattt ttcgggtcta cctccatagc gtcctctagc acgtgctgca attcggccag
     8761 ctgaagaacg ttctaaaatt aaatttcgtt caaattctgc aaacgctgcg aataaatgaa
     8821 ataataattg tcctgtagaa cttgatttat ccatcgttat attttcttct aaactatgga
     8881 aacttacacc tcgttcgtta agctcattaa ctaatgtgat taaatcctcc atattacgtc
     8941 ctagtctgtc gagtctccaa acaacaatcg tatctcctga tctcgcaaat tcaattgctt
     9001 tatctaatcc aggtctttta ctttttgaac cactaatatg gtcgctaaat atcttttcac
     9061 aaccatatgc gtttaatcgg tcctcctgta aattcagatt ttgtaatcca gttgaaactc
     9121 ttgcataacc tattttcaaa atacaaacct cctatataca tatacagtgt accataactt
     9181 aatttcaagg tcttttgtga acatagattt tttgttgggt ttttgaacac gaaaatatat
     9241 gtattactca cttatttcgg cataaaaaga gagtgtacag aaaatggtta ttttctgtac
     9301 actctcatct ttaataatat attttaaatg ttattaacaa aactaattta ataagagtca
     9361 agcatagttt acatatgtat tatgtttgaa acatatctct aattactttt tactaatatc
     9421 atttaaaatg tctcgcaatt cttcaatttc tttgttattt aattcttcat ttttcgcaaa
     9481 attcagcact aaacttttca tgtcccctcc atacagttta ttaagaaagg ttttagcagt
     9541 tttcatttta atatcgtctt ctttaatatt tgatgagtaa aaataaatat tctctgattt
     9601 gtatcgtttt ataatctctt ttttatatag tcttgtgatt aatgttctaa tcgttttatc
     9661 gctaacttct ttatattttt gaatttcaac tacaatttca ttagctgata ctgatttttt
     9721 accccatatt atattcataa catcccattc agccatagat atttcaactt gcttattggc
     9781 catttaaaac acccatttct tttaatattt tttcactgat taattcagca tttttcccag
     9841 atggctttcc atctgataaa tgtgtagcaa aataatactt atcatgattt gtaattacgt
     9901 aacctacaaa ccacccatta ttatacttcc cgtttactat acctgtacct gttttcccat
     9961 acagttcata cttttcattt ttcttaatca ataatgaaga agataattga ttctttgctt
    10021 ttttactaaa atggttattt tgttccatca tatttttaaa aactattact tgttcaagat
    10081 tagatatttt caaactatct tccatccaat agcttttata acttcccaaa tttttattac
    10141 cataatttaa ttgcttgagt tgagtcgcag tatagttctt tggtatttga tcgctaatac
    10201 gttcgaagta ccaattaact gaattttgca ttgctgtatt taaatcttgt tccttattcc
    10261 aagcatcaaa agggtaatgc ttatgattcc atgacatacg tgaattttca tcatttataa
    10321 tatgtcggtc aagtccaaac atagctaaat aaattttata agttgaatta ggagaatacc
    10381 tttttctact ttctttttcg ttataaatat agtatttgtc tttcttcatg ctgtacatga
    10441 cgaaagatcc actatttgaa ccaaaaattt tacttttatc taaaatttgg taatcgttgt
    10501 gtaagggctt tttataatta taatcagtta tggattgccc catcaaaaac tggctttgaa
    10561 ttaccatgag caaaaaagta aaaatacaaa taaaaattag aattaatttg gactgttttt
    10621 tcagattggc ttcttttata ttaattaatc ttcttttgag taatgacttt ttaccattaa
    10681 atgaatggct taatatattt ttattaaaaa atggaacatt taatacggag tccataatag
    10741 attccgcata agttttaaat tcatttttgt taatattatt aaggacaaat ctatcggctt
    10801 ctacttcatt gtcatgaatt atctttcttt ttacaatatg tactaatgga ttgtaactca
    10861 taataataga gaagatatta aagataatta aatgtaaagt atctctattt ttagcatgag
    10921 catattcatg caatattata tattttagtc ttttgtcaat tacactttta aaatatgaac
    10981 taggaatcaa aataatatat ttcccatacc aaaaagttat tggagattga atagtctctg
    11041 cttttcgaat cacaatattt tttttatatt gatggttgaa aagtatcgta tctattttat
    11101 ttttttcatt ttcgtttaga taaagtgact gtttctttaa atatttaaga tataataagg
    11161 ctttcaaaaa tttaaaactt aaaataataa ctaaaactat ccaaataact gtgcagatat
    11221 tatcaattga atcccaatta aacttatgga tatctgttgc gaactcttga ataggtttgg
    11281 tggtatttat gttatggttc aagtcgtgtg acttactttc aactgtgggc gcttgattat
    11341 tcacattatt aaatttaaaa agagagaatt taataggaat gaaaggaatt aatcctgcaa
    11401 gaagagttag ataccaaact ttataattta acatataatt aaaatagcgt tttaatatgt
    11461 acctaaaaaa taataacaat agaaatataa aacaaaagct tactatgctc attattaata
    11521 acttagccat ttcaacacct tctttcaaat atttataata aactattgac accgatatta
    11581 caattgtaat attattgatt tataaaaatt acaactgtaa tatcggaggg tttattttga
    11641 aaaagttaat atttttaatt gtaattgctt tagttttaag tgcatgtaat tcaaacagtt
    11701 cacatgccaa agagttaaat gatttagaaa aaaaatataa tgctcatatt ggtgtttatg
    11761 ctttagatac taaaagtggt aaggaagtaa aatttaattc agataagaga tttgcctatg
    11821 cttcaacttc aaaagcgata aatagtgcta ttttgttaga acaagtacct tataataagt
    11881 taaataaaaa agtacatatt aacaaagatg atatagttgc ttattctcct attttagaaa
    11941 aatatgtagg aaaagatatc actttaaaag cacttattga ggcttcaatg acatatagtg
    12001 ataatacagc aaacaataaa attataaaag aaatcggtgg aatcaaaaaa gttaaacaac
    12061 gtctaaaaga actaggagat aaagtaacaa atccagttag atatgagata gaattaaatt
    12121 actattcacc aaagagcaaa aaagatactt caacacctgc tgctttcggt aagactttaa
    12181 ataaacttat cgcaaatgga aaattaagca aagaaaacaa aaaattctta cttgatttaa
    12241 tgttaaataa taaaagcgga gatactttaa ttaaagacgg tgttccaaaa gactataagg
    12301 ttgctgataa aagtggtcaa gcaataacat atgcttctag aaatgatgtt gcttttgttt
    12361 atcctaaggg ccaatctgaa cctattgttt tagtcatttt tacgaataaa gacaataaaa
    12421 gtgataagcc aaatgataag ttgataagtg aaaccgccaa gagtgtaatg aaggaatttt
    12481 aatattctaa atgcataata aatactgata acatcttata ttttgtatta tattttgtat
    12541 tatcgttgac atgtataatt ttgatatcaa aaactgattt tccctctatt attttcgaga
    12601 tttattttct taattctctt taacaaacta gaaatattgt atatacaaaa aattataaat
    12661 aatagatgaa tagtttaatt ataggtgttc atcaatcgaa aaagcaacgt atcttattta
    12721 aagtgcgttg cttttttctc atttataagg ttaaataatt ctcatatatc aagcaaagtg
    12781 acactcttaa tattaagtta agaggttttg tgtcaaaaac gaacgttttt aactttaaag
    12841 attttatcta ttttttattc gtctgtataa taacagataa aattatggtt aaaataaata
    12901 tcagtatagt tgtaaaaata ataattttat tattttgatt tttatcttct tgctcatcat
    12961 cttcttctaa ttctttaatt ctttgctcgc gtacttcaac ttcttctctt gagccttgct
    13021 cattatctaa gatatagggt tgttggtctt ttactttcat aaattttttc tccttattat
    13081 tagaacaaca aagacaccta aagatttagg tgtctcagtt tttttaattt catttttatt
    13141 acattcggct aagcagttct ttttttataa taatcaaagc atggttacct tttgagttga
    13201 tgttttcctg agcatttagt attaatagat caattaaatc gtcattatct ttttgactta
    13261 tttcgtcttt gaattgatca atattttcta ttaaaatttt ttgattgggt tgctgtttgt
    13321 ctatagtgta atactggtca gcgcccaaac caccctcttc aatcattttc gatatttcat
    13381 tagatcgtgt ttcatttgtt ttgcttattt ctatttcttt tttatcagag ttaaccatga
    13441 ctatccccct tatatgccca ttacacacag tgtaataata catatttaaa ataacaataa
    13501 ctctgctcac taataattta ttgagggttt aataaatgac attcttggta tcgtttacat
    13561 agatgattat tattagaatt catatcaaag aggcaccttg gtcaaccaag gtgcctctta
    13621 atcgtttcaa aaacaaattc catcttaata aggatcgttt ttaatttcat tttttcttgt
    13681 tgaatttcta tgtcttattg ttaagtcata cttttaaaat gtataattat ttgttaaata
    13741 attaatctgt ttttttcggc gtcgctcggt aaacaataaa cgataagata acggcaataa
    13801 tggatataga aaagctaata aaataaacga gttcaactcc tgcaaccatt gcctgattta
    13861 ttgtgtcagg atcttgtggt ttccctgaat tttgtaaaaa ttgaagctgt cttgcattca
    13921 taatactaac aaatactgca acaccaattg ctccagcaac tggttgtaaa gttgtcatca
    13981 ctgcagtccc atgtggatat aaatgttttg gaagttgatt taacccattg gtttcagcag
    14041 gcatcataat tgctgaaaca gatagcatca acaagatata actaagaata acgatccaca
    14101 aaggcgtatc cacattcaat ctactcatca catacattgc cccacttagc acaattgatg
    14161 caggaatcat caaaacacgc gggccaaatt tatcaaatag atatcccata aacggcgaca
    14221 ttgccccatt aagtaaactg cccggcagta aaattaaccc cgcagtagct gcagttaaag
    14281 ccaatggtcc ttgcatatag ataggtaaaa ttatttctga agcaaacatc gtcatgatga
    14341 ttattaaaaa cattaaaata gcgtgtgtat acataggata tttaaatact cttaaatcta
    14401 ttagaggttc ttttaaattt aattgtctta ttgaaaataa gacaattcca atgattccaa
    14461 caattattgg aattaataca ttgatactta aaaaccctga ttcacttttt ccagcgctac
    14521 taaagccata tataacagcc ccaaaaccta tagttgaaaa aactaatgat aaataatcga
    14581 ttttaggttt agtaacttct gatacattaa ttaaaaactt agacgcaaat gcaattgaga
    14641 atattgaaaa tgggattacc ataataaata aagaacgcca acctagatat tcaacaatca
    14701 ctccagatag cgttgggcca atagttggcg caaacatgat aacaaaccca acgattccca
    14761 tgatttttcc acgtttaaag ggggggtaaa tcagcaaaaa tacattgaat ataataggca
    14821 aaagcatccc ggtcccgatt gcttgaatga accgtccaat aagaagtata ggaaaggctg
    14881 gtgccgccgc acaaattact gttccaagag taaaaatggt catagtactt aaaaataact
    14941 gtcttgtagt aaaccactgc aacaacaacg cagaaatcgg tgctacgatt cccataatca
    15001 acataaaccc tgtcgtcatc cattgtacag ttggtaaagt gatatcgaat tctttcatca
    15061 aagatgtaag ggcaatattt aataatgttt catttaatat agcaaaaaaa gctccaataa
    15121 ttagcgacaa tataatgggt aatgttttaa aatttggatc atccgctaga tactcatatt
    15181 tttggtgctt attattgttc attttaaggc cctctctatc ataaatattt aaattaacta
    15241 aaaattttaa tcatctgttt aatacttatg aaatgtattt acggtaggta ttaaaattga
    15301 tgaaatttat ataagtgctt tcaatgaaaa tgaccgttta tttatcctcc tgatttaagg
    15361 agttagaaat ttcgaaaacg attctttcca tttgttgcat ttgttccatg tcgagatatt
    15421 caatacatta tagaaaacca aagaccatca ctaattaaac gccgttttaa aatttcatca
    15481 ggattgcctt cgtctttaaa aggggcctct tttaatataa gttctactct ttcataccta
    15541 actctttcaa tgccatcgtt tcatacgccg attctcctga ttccatagca aactcagcga
    15601 taaacattgg gaatactgca ttgagttcta ttatatgctc tttcattcgt ggccatattt
    15661 cacctccagc tttaccgtat gctgttataa gttgctctaa tccttcgtcg tcgaatacac
    15721 gatggtgtcc tataaagtcc attgatgggt cggagtgggt tgcttcagtc cagtctatga
    15781 gacctgtgac gtttgcttgg ttatctacca ttatatgtcc tggatgtaag tccccatgta
    15841 tcatggtcgc atgtcgaggc catagttcgt cgttttctaa ccattgtttc catctgttcc
    15901 ataattcatc tgatacgcca taagtttctt taactttatt cattcttctt tgaaagtcat
    15961 tttttatttc ttgtatggtt ttgatattta tatgctgaac gttaatgttt tcttctggta
    16021 tgttgtgtaa atctacgagt gtttcagcta atgtgttaat aaagttttct ggtaatggtt
    16081 tgtgttcaat ttcccataca taattttgta tttctggatc tattgtggct gcgggtttac
    16141 ctgtaagttt tgggtaagca ataaggtctt ttgcatgtac tttccacttc ggtatttcaa
    16201 atgaaacatt cttctgtaag aagtctaccg tttgtttttc gggttttgtt cgtttataaa
    16261 cgtcaggtct tcttggtagt ctcaaaaccc attctactcc atgtttatct tttccaaatg
    16321 caacttggaa atcaagtccc gattcattca atgagattgt ttgaggttgg atgtgtaatt
    16381 gatatttttc tgcacattta ataatttcat tatgtcgagt cattttattg gctccttatt
    16441 tctattatat ttttcttgtg aacgtatttt ttatattgat ataaatgaac ctaatcttca
    16501 agacttcggg atatagtgta tgaaagtaat ttatgttcta atattataaa taataatact
    16561 tcttaattga tagtgctggg aatggttgtt tattaatgat tgcagttcct gagcgttatg
    16621 aacacgttgt ttttataccg aagacattaa aattatacac ttttaaatca caaaaaattt
    16681 ataaatcatc ggttatgtta ctattgttat ttactttatt ataatacttt aaagaaatat
    16741 ttaatataaa ttagtgtata gtttttaagt tatatcatga atagattgtc ctgttaattc
    16801 ccatttttta tctgatacat gtttaacaaa ccttgtatca tgtgatgtaa acaaaatgat
    16861 tccaggatat ttattcataa acatttctaa tgcttctaat gttttaatat ctaaaaaatt
    16921 agttggttca tccaaaatta acatattcgc tttcgttgaa aataatactg ctaacgataa
    16981 tttcgttctt tccccaccac tcaaaacatt acaagaacgc tcaagtgctt catttaaacc
    17041 caagttattt aaaatagctc tactgaatga ttctgatgaa tccgtttcat ccattaaata
    17101 ttgcaataat gaaacgtcac gcatgtcttc ataagcaagt tgacgatagt atgccatttg
    17161 cactttagga gaacaatcaa ttccctctat ttggtggtaa atagcttcaa gtaaagttgt
    17221 cttacctaca ccatttgcac ctacgagtgc tatatttttg ccatatggta tttggaaacg
    17281 tacttgtgtt agcagttttt gacttccttt aaccaatgtt agattttgtg caatgattgg
    17341 ataattatta tggatatcat aaattttatt ttgtggaaaa ttgaattcat gataactttg
    17401 tggtttttca acttcttcca aatgttccat tcttttttca atatgcttag cttgtttttg
    17461 agcagccttc tcaaccgtgc ctttttgttt tgatgcactt aaacgatctg gtgctatact
    17521 tttatttttt tgttttgatg atgcttgtgc catttgttgc gcttgatttc gtttagcttt
    17581 actggcttgg gacaatcttt gtttttcact tatatactgt tcatattgac gttgttgttc
    17641 taactgttct tgttcatatt gattttgata ctgtgtgtaa ttacctttaa acactcttat
    17701 tgtgccatct tcttgtatat cccaaattgt gtcagcaatt tggtctataa gtgctctatc
    17761 atgacttact ataattaaag taccatagta atattttaaa atattattca gataatcttt
    17821 accaatttta tccaagtgat ttgtaggttc atctaaaagt aatatcggac tataatttga
    17881 tatgacatta gctaatttat attttgcttt ttcaccacca ctcatactgt cgattgtatg
    17941 cataggtata tggagttcac tcattaaact accgtctaac gtgttaaaat cattttccac
    18001 atccatgtta agctgttcaa aatattgaat ttcgccatcc gtttcaactg ttccagattc
    18061 tggttttgtt ttttgagcaa tcatatttag taatgtggtt ttgccagtac cattaccccc
    18121 aataagtgct attttttcaa attggtaagc ataaagatga ccgatgttaa gtgatcgtaa
    18181 atctgtcaat ttatgattga tttggttaaa tttaattgta tattgttcca tatttataca
    18241 ctccttgtat atttaaagga cgtgtacgca aaaaatgaga caggctactc ccgtctcatt
    18301 cacattacac tttcaaacac ttaaagaatt attacgatgt tttagtattt gaaagcgttt
    18361 attattccta tcgaaggata aaaaatgaca taagtcatcc tatgagtgtg tattgcggac
    18421 aagccttttt gaattaattt aattttgtat tcaaaaaggt ttatttgagt ctcatagaag
    18481 ctgtcatttt aatcctcctt catcgataaa atagtaatgt taatataaca ttttattggt
    18541 ttttttacaa gaatctttaa atgtttaaca aaggtaggct ctaaaaatac aaattgagcc
    18601 cactattttt atttaacaca gtcgtattaa aaaatgttaa actttaaata tgccaaaaat
    18661 aattaatcac aaagaaaaga aaaaacaaat aattcaatat gcttttgatt caattgtaga
    18721 aaatggtgcc aaaggatcta ctgtaagaca aattgcgaaa ctagctaaga tgacgcctgg
    18781 acaaattaga tactattttc cgaatcattc agagttacta aatgctgtta tgtctgcaat
    18841 agaactaaaa gtaagaagga aaattgaagt aatatttaca tccgaagacc ttaatgcaat
    18901 tgacaaagca aaagtaagct tgctaacagt attaccatta gatcaagaaa gattagctga
    18961 tatggaagtt tggatggcgt ttcgctatga catacatgag tatggtcaaa gtacgcttga
    19021 cgatgggtta gaccaattat gtcatagtgt tttaacttta ttaagcaatg atcatttatt
    19081 gaaagataat ttaaacatcc accttcattc tatgaaatta cacgcattaa ttgatggttt
    19141 agctcttcat aaattactta atccaaatca aacttcaaat gaagatattc aatcaattgt
    19201 agatgaagaa ataactaggc taacgcaata aaggagggta acccatgaac tttatagtat
    19261 ggctcattat tttttgtgaa gtagcctttt gggttgttat attactcggg ttggtaacaa
    19321 gatatatctt aaaacaaaaa acactaggtc tactattcct agcacttaca ccagttatag
    19381 atttaataat acttataaca acaagtatag acctcatgaa tggagcaaca gctgaaatcc
    19441 ctcatgctat agctgcggtc tatatttcag tatctcttgt ctttgggaaa agcatgataa
    19501 attgggcaga tgatagattt agatattatg tgatgaaaca aggatctaaa ccttataaag
    19561 ctgtagggtt agcttacgct aaaaactatg ctaaaagttg gttgaaacat ttactttctt
    19621 acattatagg aacaggtatt ttgcatttga ttgttttttt aattaatgat aaaagtcgta
    19681 cagaagctat agataatgtt attcatgttt ggacaattgt cattattatt gacttaatca
    19741 tttgtatttc atatttttta tggccaccca aaaagaaagt aaatcataat taacaattaa
    19801 tttgaattta tcttattatt ctaattaata tcatttatct ctttgcattt ataagaaata
    19861 ggttatataa agaggctaat cattttatat agtgattagc ctcttattta cataatcaaa
    19921 tttcatctta ataacgaacc ttaatttcac ccaattaaat ctcgtttttt atatccaata
    19981 tagcctaaaa ttataaatac aatgctaatc atagatagaa tgacaaaact gaagatatca
    20041 aaattttctt ttggcatttg tgggagccaa ttcaatatag ctgtttttga aagccattca
    20101 ggtaagtcta aagtacctcc aaaataattg agtgcaaaag tatatccaag ataagcataa
    20161 gctatttttc caagtttggg tgcccacccg aatgcaagag tagcaagact agtgaaaaat
    20221 aatatagcag gtaaaaaatt atatccagct gcaaggaaat caataagctg catttcccca
    20281 tgaccttcca tcacgtttat tgctgtcaca cctaggctaa gtgaagccac taaaacacct
    20341 aatacgctac taaaaaatgc taaaccaata ttagtccaat atattctact acgcgtcact
    20401 ttagtagggt atatttggct aagatgaagt ttattttctt ctgaaaataa tttgttaaca
    20461 attacaatcg gcaatatagc aactaaacta accataacca ccataatcgt gctcgtaaat
    20521 gatgtttcaa tagaaacatt tgaagtagaa aacatttgtt tcatcatttc gttactttct
    20581 aagaaagtct gcatgtctcc ataaattgat ccataagcaa tgcccataac cataaatgca
    20641 actaaccaac tgatgataat actttgatta attttgcata ataaaccacg gatagataat
    20701 aatgactttt tggcattcct ctttcctttt ttttcaggaa tatagctatc tcccatatcg
    20761 cgtgcgcctt caagcataaa tgcaataata actactatga tactaaatat aaaagcaatg
    20821 gcaatcggaa gccaattatt atctgtaaaa gggtaagtga gatatgtcca accaagagga
    20881 ttaaaaatag acaactcaat gttggataca tctgtgccag cacggataat atatagcaaa
    20941 cctacaatac caagagacaa tccaatggca gatgatgagg ttggcatgat ttgagagaca
    21001 acgagagcaa tgcttgcacc cattactcct gccattccaa ttgttattcc aaaaagcagg
    21061 gcaccttgaa gagaaatcgt ttctgcatta aaactcacca ttactgcaga aataaacatc
    21121 gctattaagc cattaattaa cactatttct attattgtag caagtgaatt tgcttgtcga
    21181 cctatttgaa acgagcgtac taattctgta agccccaatt cttcttcctt acgtgtatgt
    21241 ccaattatat gcaatataga gactatcatc gcaaaaagtc cacaaaataa taacatttca
    21301 tgtgcataca tggcgcctaa agtataatct gttgctgtct caattggtgt gggacctacc
    21361 atagaaatca ttgcagggtt ttgtaatgtt tcaaacatac caattaaccc tttcccttgt
    21421 gctatctctt taaaagctgg aacaaatcct gctgaaaaca aaccaatact taaaatccat
    21481 ataatcattt ttttccaatc aagctttaga taatgcaaaa acagtgtgtt ccaaccagaa
    21541 aatttttcat gcatatgaac tcaacctcct ttccattatt tagccttcat aatgacgtat
    21601 aaataaatct tcaagtgtag gtggtgtaga ttcaagtttt ttaacaccca atttaactgc
    21661 ttcgcttaga atagaattaa ggtgtttatt atcagcagaa aatgtcgctt gattattgct
    21721 ttgtttaaaa tcaaatacgc cttgtatttc tgataattta gctacatctt cttctgtttc
    21781 gatcatcagc gttgaacgag ttaaatgacg taattcatcg agtgttccag tttctacgat
    21841 ttctccttgt ctaataatag caactctatc tgctagacgt tccacctcac ttaaaatatg
    21901 tgaggatagc aaaatagatt ttccagttgc tttaattttt tcaacttctt cttgaaatgt
    21961 tacttccatt aatggatcaa ggccagaggt cggttcatca aagatgtata agtcggaatc
    22021 aactgataat gctgcaatca aaccaacttt ttgacggtta ccttttgaat atcctttaga
    22081 ctttttctta ggatctagtt caaaacgttt aattaactca tctcgttttt ctgtgtctcc
    22141 actaccatgt aatttcatga ataaatcgat aatttctcca cccgtcaaat taccccataa
    22201 tgcaatatcc cctggaacat aagatattct tttatgaatt ttaagacttt ctttccatac
    22261 atcttttccg aatatttcta cctcacctgc atctcgttta ataactccta atagtgtacg
    22321 caaagtagta gattttcctg caccattagg accaataaat cctaaaactt cacctttatt
    22381 aactgtaaaa gacacatcat ttaaagcctt gaaatcacca aagttctttt gtaatcctgt
    22441 aattttcaca acttccctca taatagtgaa gccccctttt gtagtactcg tttctttttt
    22501 taatacttcc ttttacttat aaaaactatt ctttaatatt tgagcgtaat catgccactc
    22561 tttgagatac tgattaccaa aatcggaaat attttcaaaa gattttattt gttgaagtcc
    22621 cttttctcca aaaccggaca ttgtccaatt aagaatttca attgcttttt cgatatcaat
    22681 atcatcacga aatttagaat agtcgatgtt agcaaatatt ttttgtcgtc cattttcata
    22741 tatatggtca acttttttct caataatagc ttttacttct aatgattctt cttgaataga
    22801 atgttttaga aaatcaaata tttcaggatg cttttgttga acatataatt tttgtaaacc
    22861 aatattctca atcctattaa ataaatcctt ctcacttaaa tcaatttctc tatacatatt
    22921 ctctaaaatt tgtgtactat aattaattaa ataaatatag aggtcttttt tactattaaa
    22981 ataattaaat aatgatccct tggaaatatt cgctttttta acaatttcat ttgtagatgc
    23041 cttgtcaaaa ccatttttca caaattcttt gattgatgag ttaataatca ttttttgttt
    23101 gttcgttttc aagttattaa atatagtgtt aataaaaatg cctccttttc attcaaaatg
    23161 actacttcgg tcatttggag tttacatcat atgaccaaag tagtcaattt tttacataat
    23221 cgatgattat cagaagttcc gatgatataa ataagcgcta caagttattc gacttgtagc
    23281 gcttatttaa tgaatatggt cttttaaaac tattattagc caccaaacaa acgactccag
    23341 aagccttttt taggttgtgt ttcttcatat cgcgtacttt catcgctttt actttcatct
    23401 atatccttat gttgaatctc tgcttctttt tcttcttcct ggtgttgatt aatatttaca
    23461 gaatcagtag tatatgttgc ttcttgtgca tcaacgtttt gtctatcgtt agtagatgta
    23521 tcaaaggaat aattaaggtg tctctcttcc tctaattgat tctctaactt ttgaattttt
    23581 ttattactct ctaatgccag aacttgctga ttctcaagca attttgatct ttcctgcaac
    23641 tcttttctgt agaattcaat tgttgtttca tgacgacttt cttgtttttc aatttgatca
    23701 ttcaaagtat caatctgatt tttaaggatt tctactattt gagtatcact tttggattca
    23761 acattaatat tatctgactc ttttttttgt ttgtcttcag tagcactttc aaaaccatat
    23821 ttctttttat tttcatttac tctttgaatg attttttcta tatcggtatc ttctttaata
    23881 aacgaagtgt tttcctgttt tattgtctct atattcaatc gtttaatgtt attaaaaatc
    23941 gtttgcttac taacccctaa ttcttcactc aacattttca cgcttttcat atcatcaacc
    24001 ctttataaaa tgtttatcaa ccctttataa catattataa gcttatcacg cttaataata
    24061 aagtgattga taagtcgaaa atataaaacc gtcaaccctt ttatcaagta tttgtaaagg
    24121 gttgacggta gttgtcaagg gtttgcaaac cctttatcaa cccttgacaa cactacattt
    24181 tcccttttat aagcttattc aaagtgctat aataacctta atacaacaaa aaccccaact
    24241 actggtaata gtcggggttt ggtaataaaa cgttgcagca cgtttataaa tattttgata
    24301 tctgtattat atacaactat atcatcaaag tgcaagcaaa aaatttatgt gttcttgtaa
    24361 tgttttatta cctctatcca aaatttgaat aggaaagggg tttttattat gtctagaaaa
    24421 aacataaaaa atcaggccag tcaaaatttc tatatgctac ataaagtatt atttatcaat
    24481 gaaaaatata aaaagttaag tgatagtgca aaagttacct atgcaattct taatgataga
    24541 gtaagtttat ctattaaaaa taattggata gatcaaaatg gagatatata ttttattttc
    24601 acaaatgaaa atcttcaaga agtgttagat aaaagtaaaa atacaataac caaaattaaa
    24661 aaagaattac aagaagtggg tttattagaa caagttaaaa ctggatttaa tcgaccaaac
    24721 aaactatacc ttcatgaaat tgaaacaaat ataaatattg aaaaagaaat acaaaatagc
    24781 acttcaaaca atgacgaatc aagtgatagc aaggaatccc aaataatggg agtccagaat
    24841 cccaaacaat gggagcccag aatcccaaac aatgggagcc cagaatccca aaacttagac
    24901 tctaatgata ctgacttaag taatactgat tatatagaga ctgagaataa tgatacgaat
    24961 gacttgaatg atacatacaa caatccaata aacaataatc attcggatca tacaaatcat
    25021 caacaaaccg aatttaataa tgatgcgctt aagttccaag tcctcgaaga attgcctcaa
    25081 caacttcaag actatttaag taaatttgaa attagagaaa ttcggattat taaaagtgta
    25141 ttactcaaag gtaaaaaatc atttaataat gcacatgata cgtattaccg tttagaagat
    25201 gttgagtttg aaattgtaag tgtgttgaaa cgttttaaag cgatgctgct acaaaagaat
    25261 gaaaccgttg aagcgatgca agggtattta atgcaatcta ttaaagctga attcgaagaa
    25321 acacatgcac tttatatgcg acgtcaaaac atgaaacaac ataatatctt taatcagtag
    25381 atgtggcgtg ctttcacatt taaattaaga gaacaccctt tatattatat gtagctagta
    25441 aataaagggt tacataggag caaactattt taggagggcg cgtatggcgt tctattctag
    25501 agacttaaag cacacagata tagatattta aatgaattat atgctttacc agaagtgact
    25561 cagtatcaaa cttggggtcc tcaaagttat gaagagactc agcagttcat taatgtggtg
    25621 ttagataaag aatccaattg gatttacaat gtcctcgttg atcctgatac agataaagtc
    25681 ataggggcga tacaattagc catagatgaa gtgaaccaaa gtgctgaaat taactttatt
    25741 gtccatccaa attattgggg cgacggcgtt gcgacggata tcgcgaaaac aatcatcaaa
    25801 tatgccttta aagtactgaa actcaataga ataggggcag ccattgattc aaacaatata
    25861 gcttccggaa ttgtgttgga aaagttaggt atgaaacgag agggcatgtt gagaaaagat
    25921 aaattagtgc aagatgaata tagagacaca ttgatctatg gtcttttgag aagtgaatac
    25981 taagcgttaa tgtttataca agtgaggaag aaagagaagc acatttagtt attgaaattt
    26041 gaaattttta aaaagcaaaa tcattactta aaaaaggtta ggagtttgat ttatgagtac
    26101 aaaatacaag agaactaagt cagcttttat tgagattatt tcagacattg tatttcagat
    26161 atttgtattt attcctaata ttttcaagtt aataattcga ttttttaaaa gcgttttttg
    26221 ataaacccta gcttaaaaag caacgttttt tgatgtcttt ttgcccctgc gggaactata
    26281 gcgttcaacc ggcatggttg cccaattttc atgttaattt ttagatttgc atgtaactgg
    26341 gcaatgtcta aaaaatttgc cactggttta gaccaaaaaa tgtttgtgaa attaaaacat
    26401 atttattttg ctcatatttg cgttttaaga gcttatgtat gcttttaggt ataaaagcat
    26461 aggggttata cctagatctt taaaataacc ccttaaaatt cgaaataaag gcatttaata
    26521 atttaataag tcttgtgatg aagtttggtg aaaaggagtg gttttatgac tgctatgtgg
    26581 ttgtcaatta taggtatgtg gttttgtatt ggtatggctt tttttgctat taaggtcagt
    26641 aaaaataaaa agtagaaccc gcatttatgt tgagaagagc ccttaactaa acttgcagac
    26701 gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg gattgttaag
    26761 ggttccgagg ctcaacgtca ataaagcaat tggaataaag ttttttctta agagaaaact
    26821 aaaaaggttg tatagattgt agtaaaataa gagttaagga ggtttttatg aattcgaagt
    26881 ttaaggtttt tttatatgat ttatttattt catttttagt tacgttaatc attaattttt
    26941 cagtatattt ttttagtttg aaatctataa gttttgattt tttaatcaaa tataaatttt
    27001 acttttattg gtttgtatta tttttgtttg ttttagtaat acgttttttt ataaaaaaat
    27061 acatagatag attgcaggat gatataccta gaatagttat ggcttcatat aataaatggt
    27121 ttgtaaaaac tgattatttg ggctttactt ggactgttct ttttaatttt ctttccgaaa
    27181 attggaagaa tcttgattta caaaaatgta aatttgaaga tttggaagaa gttgaaatat
    27241 gtgatgttaa gggaccgtat tgtcctgatg ataagagaga gatgaaagtt actagaactt
    27301 attttgggcg ttataaatac aaatgtccaa agtgtaaata taaaaaaaaa ttacttaaaa
    27361 atcatattac tttagtaaat gatactattg atgaatttcg ttctaaattt agatgatttt
    27421 ttgttttttc ttgtcttgat actatataga aataactcaa agatattaaa gtgaagacct
    27481 aatcttattt agattgggtc tattttttgt ttaagttttg ggattagatt ttacaaattt
    27541 gggaaacgtt gggggctact acgaccaact taacaacaca aaatacactg ttgattccca
    27601 aaaataagga aaattattta cggaaattaa ctgtacatat tataaagatg attttaaacg
    27661 ccttaagtta cttttatcaa aaaagatacc tcgcttaata ataatatcta cactgataat
    27721 tttattgaat attgtattat taacacttaa ttttactttt aaaaatttta atagacctca
    27781 aataattgct ttcactttat tggtttttca ctttattgga ttagtaatat gtatcgatat
    27841 agtagctaaa atatctgtga atattttaga ggataatgct aaaaagtaat tgaaaatagt
    27901 caaatctata aaacgaaaat taaaaagact ttgtcttttt aattagtaaa actattatct
    27961 tttattgatt atttagtcca aaaaagacta tataatcaat agaaatttat gatgcaaaat
    28021 taattcgaaa gtaagtatga gggatattat gttgcacagg ctgttgcaca cgagtaaaga
    28081 gcataaggga tatatgccac cactttttgt ggtgggtctg gcgaagccag acatatcaag
    28141 ggtttaaaga ttaacccagt gccatcactt tttttctttg ttgcacaggt tgttgcacca
    28201 atatatagtg ttgttgcaca tcatgttgta cctatatatg gtgttgttgc acacattgtg
    28261 caacatagta aaaacaagaa aatagtatta tttgcatcaa tcaacgagtg gattacatat
    28321 atgtttattt ggaatttttt ctttaataat ttcaataaag tataaaggaa aacataagaa
    28381 tttattatcc caagtggagt aattttaaaa tatctttaag cttttttatt agaaattgga
    28441 ttgatttggt tagctcatat tagtatgaat cgaactgtcg aaaagggtct tgaatatgca
    28501 attggattta ataaaacaac aattcaaaag tttaaataaa aaggagtttt att
//
