LOCUS       NZ_CP118570            27936 bp    DNA     linear   CON 15-APR-2024
DEFINITION  Enterobacter hormaechei strain 2020CK-00199 plasmid unnamed3.
ACCESSION   NZ_CP118570
VERSION     NZ_CP118570.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15907134
            Assembly: GCF_028898905.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter hormaechei
  ORGANISM  Enterobacter hormaechei
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
REFERENCE   1  (bases 1 to 27936)
  AUTHORS   Young,E.L., Hergert,J., Casey,R. and Oakeson,K.F.
  TITLE     2020CK-00199
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27936)
  AUTHORS   Young,E.L., Hergert,J., Casey,R. and Oakeson,K.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2022) Utah Public Health Laboratory, Utah Public
            Health Laboratory Infectious Disease submission group, 4431 S 2700
            W, Salt Lake City, UT 84129, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20.0x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028898905.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 22:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,064
            CDSs (total)                      :: 4,948
            Genes (coding)                    :: 4,841
            CDSs (with protein)               :: 4,841
            Genes (RNA)                       :: 116
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 44 of 107
            Pseudo Genes (incomplete)         :: 75 of 107
            Pseudo Genes (internal stop)      :: 11 of 107
            Pseudo Genes (multiple problems)  :: 22 of 107
            Pseudo Genes (short protein)      :: 1 of 107
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118570.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27936
                     /organism="Enterobacter hormaechei"
                     /mol_type="genomic DNA"
                     /strain="2020CK-00199"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:158836"
                     /plasmid="unnamed3"
                     /geo_loc_name="USA"
                     /collection_date="2020-05-06"
     gene            <1..658
                     /locus_tag="PXV21_RS25105"
                     /old_locus_tag="PXV21_25105"
     CDS             <1..658
                     /locus_tag="PXV21_RS25105"
                     /old_locus_tag="PXV21_25105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /protein_id="WP_274901061.1"
                     /translation="AASSLTLQQCQNFSVVLERTVRELNGESCLSLEEAPPTKQQIVCS
                     RSFGVKITEYESLRQAICQHAERASEKLRKEHQYCRHISVFIKTSPFAIKEPYYGNVAT
                     EKLLTPTQDTRDIIAAATTALERIWRDGHRYAKAGVMLNDFTGSGVSQLQLFDERPPRP
                     HSAELMRVLDGINNSGLCKVWFAGRGIAPSWQMKRDMLSPAYTTRWRDIPVARIG"
                     /name="DUF4113 domain-containing protein"
     gene            1070..1945
                     /locus_tag="PXV21_RS25110"
                     /old_locus_tag="PXV21_25110"
     CDS             1070..1945
                     /locus_tag="PXV21_RS25110"
                     /old_locus_tag="PXV21_25110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098982.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_004098982.1"
                     /translation="MNENVYIGEVIGPDCESVNNKLTVTSKATVQPVALMRLNVFVPSS
                     RPAKGTRTSIDATSVLKDLEFSRREGYDDIRITGERLSMAIDFKVWVGIIEAFSKYGLK
                     TNSIKLTFHEFAGMCRFESKRFDSRLRKSISEALTRIRGKTITFTRSDSEGLQKVSVTG
                     LLKTGELDFANDQVELEADQRLWELYQTDYTVLLRHKPINALTRKEAAQALYTFIESLP
                     TNPVPISFKRIRDRLSLLSPVKEQNRIIKLALKQLQDIGYLDHSITKKGKETFILIHRR
                     SANLKPGTAV"
                     /name="RepB family plasmid replication initiator protein"
     gene            2570..3196
                     /locus_tag="PXV21_RS25115"
                     /old_locus_tag="PXV21_25115"
     CDS             2570..3196
                     /locus_tag="PXV21_RS25115"
                     /old_locus_tag="PXV21_25115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_004098977.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVLT
                     WYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANQAADVLKDYPE
                     MCLASSRVCDRKAHRDAWAESMTIFETQNDKAQQEIESLVKEVIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            3193..3495
                     /locus_tag="PXV21_RS25120"
                     /old_locus_tag="PXV21_25120"
     CDS             3193..3495
                     /locus_tag="PXV21_RS25120"
                     /old_locus_tag="PXV21_25120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197636.1"
                     /translation="MRNRANTPSRDEAAFINGGTAGIDNTKVTSERPLAVSKAKPVSIS
                     FFEENLKDIDDLITGEMISGKSRVNRSDVVRAAVEALKSLSKTEISRLIAEAKQR"
                     /name="hypothetical protein"
     gene            complement(3919..4710)
                     /locus_tag="PXV21_RS25125"
                     /old_locus_tag="PXV21_25125"
     CDS             complement(3919..4710)
                     /locus_tag="PXV21_RS25125"
                     /old_locus_tag="PXV21_25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098975.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_032667567.1"
                     /translation="MSGLLSYSHPQQPAQMPVAIDYPAALALRQMALVQDELPKYLLAP
                     EVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPFVQLATLKQRTEK
                     AARTAGRAPAGSQAHRLVPLSDHHYVSQLQMMVATLKIPLERRNKRTGRMEKARIWEIT
                     DRTVRTWLSEAVESAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSIS
                     STEVYTKVFALDVAARHRVQFAMPEAEAVALIKKLTPDQST"
                     /name="site-specific integrase"
     gene            complement(4707..5450)
                     /locus_tag="PXV21_RS25130"
                     /old_locus_tag="PXV21_25130"
     CDS             complement(4707..5450)
                     /locus_tag="PXV21_RS25130"
                     /old_locus_tag="PXV21_25130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004098973.1"
                     /translation="MTDIQAATESIVAATSHPVSVQLINQGAGIWGNVATGLITGLLTG
                     GITLTGIWLTHYFTLKRERQASEDKMKKELHYIATELVFMLERYAEGCFRVVTDDGQDD
                     DAPQPERKAVTNYPELNLIDVSGDWRTLEPRLMYRIRELPVLQDEAHRAIAYAAEYSDP
                     PWHKDYFRERQYQFTRLGINAVILAVRLRKATGMPETRLTGHDEWSAVSVFRKVWRRER
                     ALRAAEATRNREWNQVVIPDGMSNQ"
                     /name="hypothetical protein"
     gene            complement(5501..5851)
                     /locus_tag="PXV21_RS25135"
                     /old_locus_tag="PXV21_25135"
     CDS             complement(5501..5851)
                     /locus_tag="PXV21_RS25135"
                     /old_locus_tag="PXV21_25135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000493378.1"
                     /translation="MFTAFNERNDFSYAFEKIRNAISAPGENNLYAATELGLGILLRKY
                     EQFRQELDAAGELGNWEYDLDTYNHCIAVLQRYFTGNPSGLTERDARIYSHYLQTEHKR
                     FVKLAEELAAGR"
                     /name="hypothetical protein"
     gene            complement(6476..8284)
                     /locus_tag="PXV21_RS25140"
                     /old_locus_tag="PXV21_25140"
     CDS             complement(6476..8284)
                     /locus_tag="PXV21_RS25140"
                     /old_locus_tag="PXV21_25140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572050.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_032413492.1"
                     /translation="MTSAFVNEEAVLRIGEVREVSGRTLSVLVDKNKNLSDLFYHGKVL
                     KNVSVGSFIEVKKGFMSLIAKVETEKIVEEKSPVGSGSDSLRFRRYLTASLAGYIDRNG
                     RFTGGTRELPLIGNEVFLMSEEQLHLIHSIAPAGESGLNFSRTDLEDIDITLPISGLLN
                     SHIAIFGNTGSGKSNTLAALYQHGYEALKNLLGEGFRSRSRFLLFDFNGEYGGRSCITR
                     DKVVYNLSTHDEEGDRIPMPAEILLEHEILSVLTDATDKTQKPFLKRVLEFKKRVESKL
                     NPQSYFREILKRRVTETLFGCEKKKSDDLIDLFRPVLKDEDLIADIEFFYNNGGVWRTK
                     TGVYFSNEENTHQCNMYQRAQNYEFPEDIMEELLDYMYVQLIIEYLSSRSNPEHLSPVI
                     NRMSGLKKDIRKIFNTASGGTIWAETNFVVLNLNMVNLTMKKTLPLLMAKWAYSAKKMD
                     KVPSTLHLIIDEAHNILSNTSFRESESWKDYRLETFEEIIKEGRKFGVFVTISSQRPND
                     ISPTIISQAHNYFIHRLINQNDLYAIEKSVSYIDRMTEESIPTLATGTCIFSGVICPMP
                     LKLRINELSFRKKPHSHTLNFEDLML"
                     /name="ATP-binding protein"
     gene            complement(8281..9327)
                     /locus_tag="PXV21_RS25145"
                     /old_locus_tag="PXV21_25145"
     CDS             complement(8281..9327)
                     /locus_tag="PXV21_RS25145"
                     /old_locus_tag="PXV21_25145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="WP_058684107.1"
                     /translation="MATYRAYYGQDRDREYFERIFQSANINFIIGSGASLPAISVLGDI
                     ESELEALVRAGNDDEYFSKSESFLDNVWKANNVLLKRSRPAEVILPTLIDDVVSTQNNY
                     AKLMRALEMLLTRRRTGLLPRRINLFTTNYDLFIEDAAVKNNNVILNDGFRQRADIYNR
                     TVFDAKCFYQTIHATGNLYNYSVELPTVNLIKLHGSLSWHSYDKEIYYSIKDMKPVAFN
                     TPKEKQDWVMSHQLVLPRKDKFRETLLENVYYDLLRTYSNELDKEGSLLIVFGFSFADE
                     HIESLTKKALRNATLKIVIFAYNEAAKDLFLGKFRDYSNVDVVFTPGAPLDFKKMNEII
                     TSFLGGMK"
                     /name="SIR2 family protein"
     gene            9511..10203
                     /locus_tag="PXV21_RS25150"
                     /old_locus_tag="PXV21_25150"
                     /pseudo=""
     CDS             9511..10203
                     /locus_tag="PXV21_RS25150"
                     /old_locus_tag="PXV21_25150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            <10219..10362
                     /locus_tag="PXV21_RS25155"
                     /old_locus_tag="PXV21_25155"
                     /pseudo=""
     CDS             <10219..10362
                     /locus_tag="PXV21_RS25155"
                     /old_locus_tag="PXV21_25155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /name="IS110 family transposase"
     gene            10644..11825
                     /locus_tag="PXV21_RS25160"
                     /old_locus_tag="PXV21_25160"
     CDS             10644..11825
                     /locus_tag="PXV21_RS25160"
                     /old_locus_tag="PXV21_25160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4268 domain-containing protein"
                     /protein_id="WP_013023770.1"
                     /translation="MYKIDRQNNSLKSLMEVSFSSLGFRERDHLQEWLANNPQALTKKD
                     DKEDELLIIQKEFAGFDETNERLDLLAIDKKGNLVIIENKLDDSGRDVVWQALKYAGYC
                     ANLRQESVVEIFQLYLTQHEPSEIRPAAEVIAEFMGWESLKEGVLNRKGTQRVIMVAAN
                     FRKEVTNTALWLMQFGIRVQCFKATPYLFAEDVFVDIRQVIPTPEAESYMIGMAQKEAE
                     EQSTSSSSELQQRHYLRREFWSLALEKFRTSTCSLFNNRAPTTDHWLAAGSGVSGVPFE
                     VIFSQKDARIQLNISRSDAVENTWLFERLSERKTHIESQFGGMLNWRLLPERKSCQVVC
                     AKAFDGGNKELWPDIISWMIDGMTRLEKAIRPSLQELAVELKKSGLITEGGDE"
                     /name="DUF4268 domain-containing protein"
     gene            12321..12698
                     /locus_tag="PXV21_RS25165"
                     /old_locus_tag="PXV21_25165"
     CDS             12321..12698
                     /locus_tag="PXV21_RS25165"
                     /old_locus_tag="PXV21_25165"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_032667578.1"
                     /translation="MQKNVTPGRRKGCPNYSPEFKQQLVAASCEPGISISKLVLENGIN
                     ANLLFKWRQQWRDGKLLLPSSESPQLLPVTLDATAVQPKSLAEDPGLSISCEVTFRHGT
                     LRLNGTVSEKFLALLIQELKR"
                     /name="transposase"
     gene            12695..13042
                     /gene="tnpB"
                     /locus_tag="PXV21_RS25170"
                     /old_locus_tag="PXV21_25170"
     CDS             12695..13042
                     /gene="tnpB"
                     /locus_tag="PXV21_RS25170"
                     /old_locus_tag="PXV21_25170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_032667561.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFI
                     FRGRSGSQVKLLWATGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLMEGIDWRQ
                     PKRLLTSLTML"
                     /name="tnpB"
     gene            13093..14631
                     /locus_tag="PXV21_RS25175"
                     /old_locus_tag="PXV21_25175"
     CDS             13093..14631
                     /locus_tag="PXV21_RS25175"
                     /old_locus_tag="PXV21_25175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="WP_032667560.1"
                     /translation="MNDASSDDILLLKQRLTEQEALNRALLEKLADREREIDHLQAQLD
                     KLRRMNFGSRSEKVSRRIAQMEADLNRLQQESDALTGLVDDPAVQRPLRQTRTRKPFPE
                     SLPRDEKRLLPAEPCCPECGGSLNYLGEDAAEQLELMRSAFRVIRTVREKHACRRCDRI
                     VQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELSRSLLSGWVDA
                     CCRLLSPLEEALRNYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWTYVRDDRNAGSALT
                     PAVWFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRITEAACWAHARRKLHD
                     VHVRTPSALTEEALKRIGELYAIEAEIRGMPAEQRLGERQQKAKPRLKSLESWLREKVK
                     TLSRHSELTKAFAYALNQWPALAYYAGDGWAEADNNIAENALRLVSLGRKNWLFFGSDH
                     GGERGALLYSLIGTCKLNSVEPESYLRYVLDVISDWPVNRVSELLPWRVALPTE"
                     /name="IS66 family transposase"
     gene            14742..15956
                     /locus_tag="PXV21_RS25180"
                     /old_locus_tag="PXV21_25180"
     CDS             14742..15956
                     /locus_tag="PXV21_RS25180"
                     /old_locus_tag="PXV21_25180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /protein_id="WP_005012528.1"
                     /translation="MLMSVFHNWLLEIACENYFVYIKRLSANDTGATGGHQVGLYIPSG
                     IVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRWGR
                     GSPLQNPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISG
                     PAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQLLDRR
                     RVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEH
                     GLRHFATQAITEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQILNEADK
                     IHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTGL
                     YADIP"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(15990..17423)
                     /locus_tag="PXV21_RS25185"
                     /old_locus_tag="PXV21_25185"
     CDS             complement(15990..17423)
                     /locus_tag="PXV21_RS25185"
                     /old_locus_tag="PXV21_25185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_032667557.1"
                     /translation="MSEFELLAQDLLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAEL
                     LRKVGKNEWSRETLNRWINGKCSPKALTLAEEELLRKMLPEAPAHHPDYAFRFIDLFAG
                     IGGIRKGFETIGGQCVFTSEWNKEAVRTYKANWFNDPQEHTFNLDIREVTLSDKPEVPE
                     NDAYAYINEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARII
                     RAKKPAIFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFL
                     PQHRERIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEY
                     LYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFA
                     NEENQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKL
                     LEPYILKAVYADSCKVERI"
                     /name="DNA cytosine methyltransferase"
     gene            17572..18269
                     /locus_tag="PXV21_RS25190"
                     /old_locus_tag="PXV21_25190"
     CDS             join(17572..17821,17821..18269)
                     /locus_tag="PXV21_RS25190"
                     /old_locus_tag="PXV21_25190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558267.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_108082295.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGAGCRATARIMGVGLNTILRHFKKLRPHSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLGLLSAFEVVVW
                     MTDGWPLYESRLKGELHVISKRYTQRIERHNLNLRQHLARLGRKSLSLSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            18423..19259
                     /locus_tag="PXV21_RS25195"
                     /old_locus_tag="PXV21_25195"
     CDS             18423..19259
                     /locus_tag="PXV21_RS25195"
                     /old_locus_tag="PXV21_25195"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_123615964.1"
                     /translation="MSRLNPKSTTLRTLFLRSGNQCAFPGCDVELINSYGQYVGNVCHI
                     EAAEVGGERYNKSQTDEDRRAYSNLILLCANHHKVTDDVDMYPVQVLHSMKTTHERTVY
                     GRNIAENKVTAFVNSTHGETVNLPQNLYKVRNSILEIFREEAFSGLVDHARNYFSHFVG
                     VPKATRTLYAQILLISESADHCTIIDIRKVPQFLGVAMEFLHVHYTILENAGLLSEQII
                     DDDVHPVRLYRVFTTFDRNDMQAWLLQSIRNYYLQSQRQTDFVELVTDLNFNLMDS"
                     /name="hypothetical protein"
     gene            19458..20426
                     /locus_tag="PXV21_RS25200"
                     /old_locus_tag="PXV21_25200"
     CDS             19458..20426
                     /locus_tag="PXV21_RS25200"
                     /old_locus_tag="PXV21_25200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /protein_id="WP_016809156.1"
                     /translation="MKDQITHLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLDD
                     EAIQAWYESAAPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLR
                     CPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     LHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5-like element IS903B family transposase"
     gene            21139..21525
                     /gene="stbA"
                     /locus_tag="PXV21_RS25205"
                     /old_locus_tag="PXV21_25205"
     CDS             21139..21525
                     /gene="stbA"
                     /locus_tag="PXV21_RS25205"
                     /old_locus_tag="PXV21_25205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001039463.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRQNRKNVLHNTHDKSSAKGAAESVLHNTQPSEPEAQESEKAESP
                     GIIDKEFFNKIGENFDPKKFNKKF"
                     /name="stbA"
     gene            21534..21725
                     /locus_tag="PXV21_RS25210"
                     /old_locus_tag="PXV21_25210"
     CDS             21534..21725
                     /locus_tag="PXV21_RS25210"
                     /old_locus_tag="PXV21_25210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000861580.1"
                     /translation="MKVAVINYSGSVRKTLISSYLLAPRLTGAKFYAVETINQSASDLG
                     IENVTSFKGDDFSRLIEG"
                     /name="hypothetical protein"
     gene            complement(21736..22204)
                     /locus_tag="PXV21_RS25215"
                     /old_locus_tag="PXV21_25215"
                     /pseudo=""
     CDS             complement(21736..22204)
                     /locus_tag="PXV21_RS25215"
                     /old_locus_tag="PXV21_25215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            22738..23493
                     /gene="repE"
                     /locus_tag="PXV21_RS25220"
                     /old_locus_tag="PXV21_25220"
     CDS             22738..23493
                     /gene="repE"
                     /locus_tag="PXV21_RS25220"
                     /old_locus_tag="PXV21_25220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="WP_000807690.1"
                     /translation="MAEIAVINHKKRKNSPRIVQSNELTEAAYSLSRDQKRMLYLFVDQ
                     IRKSDGSLQEHDGICEIHVAKYAETFGLTSAEASKDIRQALKGFAGKEVVFYRPEEDAG
                     DEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAM
                     RLYESLCQYRKPDGSGVVSLKIDWIMERYQLPQSYQRMPDFRRRFLQASVDEINSRTPM
                     RLSYIEKKKGRQTTHIVFSFRDITSMTIE"
                     /name="repE"
     gene            23762..>24222
                     /locus_tag="PXV21_RS25225"
                     /old_locus_tag="PXV21_25225"
                     /pseudo=""
     CDS             23762..>24222
                     /locus_tag="PXV21_RS25225"
                     /old_locus_tag="PXV21_25225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(25024..25350)
                     /locus_tag="PXV21_RS25230"
                     /old_locus_tag="PXV21_25230"
     CDS             complement(25024..25350)
                     /locus_tag="PXV21_RS25230"
                     /old_locus_tag="PXV21_25230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201125.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C2H2-type zinc finger protein"
                     /protein_id="WP_004201125.1"
                     /translation="MEELFTCPICKLSFGHKARLRKHIKKHTKSLEKNLAKANSTKKAE
                     HEKMLIQERIARTGSAFKNESERNKYFERRRAENPIFDIDTPIRKASFIVNAGAFGLGK
                     SRKN"
                     /name="C2H2-type zinc finger protein"
     gene            25532..25813
                     /locus_tag="PXV21_RS25235"
                     /old_locus_tag="PXV21_25235"
     CDS             25532..25813
                     /locus_tag="PXV21_RS25235"
                     /old_locus_tag="PXV21_25235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001568067.1"
                     /translation="MRVAESIILDALTRGGCIKTFYRISSRQAAESATRIPEGYILESP
                     GEREDIVLSRADFHALEKLLEQKETWEQVVGVTCFGGATWQLRPTVQS"
                     /name="hypothetical protein"
     gene            25867..26478
                     /locus_tag="PXV21_RS25240"
                     /old_locus_tag="PXV21_25240"
     CDS             25867..26478
                     /locus_tag="PXV21_RS25240"
                     /old_locus_tag="PXV21_25240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008455304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2913 family protein"
                     /protein_id="WP_000176305.1"
                     /translation="MTLTEKTGHLAWCALVALALARQEQGELSPAQENLFLTRWLAAAL
                     KQRRFSRDVAQDIGWLLNQGRLLGVRAKLADKLGYVWRSCSGELTEQNDMFRLTYALET
                     AKDMGWNYRVMSDREWAGRYALVLNPGVNGVYLLRTNLDAAFDDNGQQTNPLTVRLTGN
                     VTGIMKLLNRCGWQAEPESDASLPHQFSLMARQGVPGKGD"
                     /name="DUF2913 family protein"
     gene            complement(26475..>26606)
                     /locus_tag="PXV21_RS25245"
                     /old_locus_tag="PXV21_25245"
                     /pseudo=""
     CDS             complement(26475..>26606)
                     /locus_tag="PXV21_RS25245"
                     /old_locus_tag="PXV21_25245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /name="ISNCY family transposase"
     gene            complement(26663..27655)
                     /locus_tag="PXV21_RS25250"
                     /old_locus_tag="PXV21_25250"
     CDS             complement(26663..27655)
                     /locus_tag="PXV21_RS25250"
                     /old_locus_tag="PXV21_25250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001145103.1"
                     /translation="MPVQDVIPPYEQMYLLNQQLICNADQFKHAVITVGGQAVQYWISY
                     YHAQYGDRLPDERLTTSVDCDYSARKDDIAAIAKTLNVKTWENKDGQPPSLAQFMLIDQ
                     DTHDIKRDDGRLFAVPDAPDEPNVVDIIDRPGGFDRSDFQGKKLYLYTAPFYVEATGPG
                     MPEMNEKVRVLNPVACMRSRFSNLIALRRDAEIEIARINALKIPCYFFLIEQFDEQPFK
                     VARGIFMDLWRLANDESCLRHQAFWHSWQGPLLEGQQSNNITLIDVLEGVHVYLEGHLD
                     DFEIPEAFVTKEVPLKLAQLRERWERYVVLNAEWAARGRRGFERNPRDD"
                     /name="hypothetical protein"
     gene            complement(27704..27859)
                     /locus_tag="PXV21_RS25255"
                     /old_locus_tag="PXV21_25255"
     CDS             complement(27704..27859)
                     /locus_tag="PXV21_RS25255"
                     /old_locus_tag="PXV21_25255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000075580.1"
                     /translation="MSPVQAKQKQHERYEAVAVQVLRGRAGYKPAVKSRFSKSASSKFA
                     HTIAFA"
                     /name="hypothetical protein"
     Typing          complement(20656..20913)
                     /name="MOBF"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.439"
                     /coverage="96.0"
                     /evalue="1.58e-50"
     Typing          1071..1945
                     /name="rep_cluster_1418"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22599..22984
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.45"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 cgctgcctca tcgctaactt tgcaacagtg ccaaaatttt tctgtggtcc ttgagcgaac
       61 ggtacgggaa ctgaacgggg aaagctgcct ttcgcttgag gaagcccctc cgacgaaaca
      121 gcaaattgtc tgcagccgca gttttggcgt gaagatcacg gagtacgagt cactccgtca
      181 ggctatctgt cagcacgcag agcgggcctc tgaaaaactg cgtaaagagc accagtattg
      241 ccggcatatt tccgttttca tcaaaacgtc tccgttcgcc attaaagagc cttactacgg
      301 caacgtggct acggaaaaac tgcttacacc cactcaggac accagggaca tcattgcagc
      361 cgccacaacg gctctggagc gtatctggag ggatgggcac cggtatgcca aagccggagt
      421 tatgctgaat gacttcaccg gctccggcgt ttcgcagctg cagctgtttg acgaacgccc
      481 gccacgccct cacagtgctg agctgatgag ggttctggac gggatcaaca actcagggct
      541 gtgtaaagta tggtttgccg gtagaggaat tgcgccatcc tggcaaatga aacgcgatat
      601 gctctcccct gcgtacacca ctcgctggag agatatcccc gttgcgagga tcggttaaat
      661 tttgcctttc agagagagcc agcagtgctc gccgcagccg aacgacaggg cgaagcccgc
      721 gagtgagcga ggaagcacca ggggagctga agccttttaa agcaccttac gcacttaagt
      781 tctatagatt ccataatgag ttatccacat atcctttgag tagatccaat aacttaccct
      841 tagttatcca aatagatcca aactgatccc tttagcggca aaacctttgt ttacgggctt
      901 cgtagcgatt tcaggtgtgt cgtagtggga aaaaggtgtt ctgaagcggg aaaaaggtgt
      961 gtcaaaacgg ggtaagggtg ggtagaatcg ggaagaaagg tgtgtcaaaa cgggaaatag
     1021 ttaatattta ggcacatatc gatcatatgc tatgaatgga tataactata tgaatgagaa
     1081 tgtttatatc ggcgaggtta taggtccaga ttgtgaaagt gttaacaata aactcaccgt
     1141 cacaagtaag gccacagttc agcctgtagc cctgatgaga ttaaatgttt ttgttccttc
     1201 aagcaggcct gcaaagggca ccagaacatc aatcgatgcg acctctgttc tcaaggatct
     1261 ggaattctca aggcgggagg ggtacgacga tattcgtata accggtgaac ggttgagtat
     1321 ggccatcgac ttcaaggtat gggtcggtat catagaagct ttcagtaagt acggtttaaa
     1381 aaccaacagc attaagctta cttttcatga gtttgctgga atgtgccgct ttgagtctaa
     1441 gagattcgat tcccgtctta gaaaaagtat ttcagaagct ttgaccagga tacgtggcaa
     1501 gaccattacc tttacccgta gcgactcaga gggccttcaa aaagtttccg taacaggttt
     1561 gcttaagaca ggtgaactgg attttgcaaa cgaccaggtg gaacttgaag ctgatcagcg
     1621 actatgggaa ctctaccaaa ctgattacac tgttctgcta cgacataaac cgataaacgc
     1681 tttaacccga aaggaagcag ctcaggccct gtatactttc atcgaaagcc tgcctacgaa
     1741 cccagtcccc atatctttca aacgaatacg agacaggctc tcattgctct ctccggtaaa
     1801 ggaacagaac cgtatcatta aactggccct caagcagttg caggatattg ggtaccttga
     1861 ccacagcatc accaaaaaag gtaaagagac tttcattctg atccaccgtc gctcagcaaa
     1921 tctgaaacca ggaacagctg tataaggtgt gtcaaaacgg gaaagcaacg cgattaaggt
     1981 gtgttgaaac gggaggtctc ttcttaaaca tcttgatagg tgtgttgtag ggggaagcct
     2041 cgccttaaac gtcttaatag gtgtgttgta gcgggatgag aacctgttaa atgtgtgttt
     2101 ttatctgtat atacttacgc accttcccac ttcaacacac ctttttggat agaagtgaga
     2161 agctatcccg cttctcacca ccttttacca aatttgtctc accgactccc cacttcgaca
     2221 caccgaagat tcaaaggctt cccactacgc cccacttttt gcttcacgcg gtcataactg
     2281 gttgatacta ccctccctaa aggtagcctg gagttgaaag ccgcattatg tggttctatg
     2341 gggatttcgg ataaaggcac cactttgcca tcttgttatc ctgttatctt gttatcttgt
     2401 tatattgtta tcctaacatc ttactaattt gttaagattc aaagataatt caattataaa
     2461 tcatgtagtt aacaacttaa caagatatta acttaataaa ggcattgcaa tattgtcgcc
     2521 tgtttggcaa tattaagttg ttaacttaac aacttaatat gaggctatga tgataatagt
     2581 attgggtagt caaaagggtg gggttggtaa aagtacactg gcggtatcta tagctgcgta
     2641 tctgatgtca ctgggcaata gagtgatcat tgtcgacgca gatgaccaga aatctgtatt
     2701 gacctggtac aacaatcgtc ctgaagatct tccccatatt ccggttactg gcgcaacagg
     2761 caacatcaaa gccatgctaa aggaacacga gaaatcttat gactttgtca tcgcagactg
     2821 tgctggccgc gacagtgcag aaatgcgtag tgggttgatg gccgctgacg tattcatttc
     2881 tccgttgcgg ccttctcaga tggacctgga tgtagtgcct catacatgct ctgtttttac
     2941 agcagcaaaa gattttaatg aggacgtccg gggatatctc gttttaaaca tgacgcccac
     3001 gaacatgttt gtcaatgaag caaatcaggc agctgacgta ctcaaggatt atcctgaaat
     3061 gtgtctggct agctcccgag tttgtgatcg aaaagcgcat cgagatgcct gggcagaatc
     3121 aatgacaatt tttgaaacgc aaaatgacaa agcacaacaa gaaatcgaat cgttagttaa
     3181 agaggttatt ctgtgagaaa tagagcaaat actccatctc gtgatgaggc agcgtttatt
     3241 aacggtggta ctgctggtat tgataatacc aaagtgactt cagagagacc attggctgta
     3301 agtaaagcaa aaccagtgag catttccttt tttgaagaaa acttaaaaga cattgatgat
     3361 cttataacgg gtgaaatgat ttcaggtaaa agcagagtga atcgttctga cgtagtcagg
     3421 gcagcggtag aggcactaaa aagtttatca aaaacagaga tatccagatt aatcgcagaa
     3481 gcgaaacaac gataacatct tgttatcttg ttatcttgtt atcttgttat cttgttatct
     3541 tgttcagggt ggtaacacct tttatatcga ggcaacaact tcgcgatagt gaaaatttgc
     3601 ggatggcctc agtcctatac ataaggggat atacatgaat tcaaatacta caatcgcctt
     3661 acatttttcg cttgcattac tatttacgtt gctatcagtg gctggtagca accatgattt
     3721 agcaggagtt gtatctcaat tattccttat tttcatggct gcattttttt tctttagggc
     3781 aatgagggcc tttctgaaca tcattaatgt gattgatagc tgtaaaaggt gaggcaggat
     3841 aagcccccat taagcttgga ctgtttccca cacaagaact actttaggtt gaaacctggg
     3901 gtattaccca tagttgacct atgtagattg gtctggggtt aactttttta tcaacgcaac
     3961 agcttcagct tccggcatgg cgaactgcac acgatggcgc gccgcgacat cgagcgcaaa
     4021 caccttcgta tagacctccg tcgagctaat cgatttgtgg cccatcaggc tctgcaaaac
     4081 cttcagtggt atgccggcat acagcatgtg catcgcgtag gagtgacgga acgtatgggg
     4141 ggtcaccggt actgagaacg tcaccccgtc ggccgctgcg gactccaccg cttcgctaag
     4201 ccaggtgcgg acggtacggt ctgtgatctc ccagatgcgc gccttctcca ttctgccggt
     4261 gcgcttgttt cgtctttcca gcggaatttt cagggtggcc accatcatct gcagctggct
     4321 gacgtagtgg tgatcggaaa gcggaaccag acgatgagcc tggctaccgg cgggagctcg
     4381 gccggctgtc ctggccgctt tttcggtgcg ctgcttaagc gtggccagct gcacgaacgg
     4441 atacggtggc gccagcgaaa aatccccccg ggtcagcgcc agcgcctcgt tgatacgtgc
     4501 gccggtgttc cagagggttg ccagcagcat cttgcggtgc aaatcgggca cataatggag
     4561 cagggcgctg acttccggtg ccagcaggta tttcggtagt tcatcttgaa cgagcgccat
     4621 ctggcgcagg gccagcgcgg cgggatagtc aatggccacc ggcatttgcg ccggctgctg
     4681 cgggtgagaa tatgataaga ggccgctcat tggtttgaca ttccatcagg tatcactact
     4741 tgattccact ccctgttgcg ggtagcttca gcagcgcgca gggctctttc gcgtctccag
     4801 actttacgaa acacggaaac tgcagaccat tcatcatgac ctgtaagacg tgtttcgggc
     4861 atcccggttg ccttgcgcag acggacggca agaatgacag cgttgatgcc caagcgcgtg
     4921 aactgatact gccgttccct gaaatagtcc ttatgccaag gagggtcgga gtattcggcg
     4981 gcatatgcaa ttgccctgtg ggcctcatcc tggagcaccg gcagttcacg gatgcgatac
     5041 ataagacgtg gctctaaagt ccgccagtca ccggagacat cgatcagatt cagttcaggg
     5101 taattcgtga cagcttttct ctcaggctgg ggggcatcat catcctggcc gtcatccgtc
     5161 acaacccgga aacaaccctc agcataccgt tcaagcatga ataccaactc ggtggcaatg
     5221 taatgcagtt cctttttcat tttatcttct gacgcctgtc tctcacgctt aagcgtgaaa
     5281 taatgtgtca gccagatgcc agtgagtgtt atacccccag taagcaggcc agtgataagc
     5341 ccggttgcca cgtttcccca gatccccgcc ccttgattaa tcagctgtac ggaaaccgga
     5401 tgggatgtcg cagcaactat actctcagtt gcggcctgta tatcagtcat tgatcattta
     5461 cccctttata ttcctgagaa atcccgccct ctgtccgtag tcagcggccg gcagccagct
     5521 cttcagccag tttcacaaac cttttgtgct cagtctgcag gtaatggctg taaatccggg
     5581 catcacgttc tgtcagtccg gatggattgc cggtgaagta acgttgcagc accgcaatac
     5641 agtgattgta ggtatcgaga tcatattccc agtttcccag ctcaccggcc gcatccagtt
     5701 cctggcgaaa ctgctcgtat ttacggagca gaatgccaag acctaattct gttgcagcat
     5761 aaagattatt ttctcctggc gcggaaatcg cattacggat tttttcaaaa gcataactga
     5821 aatcatttct ctcattgaat gcagtaaaca tgtcctttcc tcagttgaat agttagccgt
     5881 gcaattttac cacacctcaa tcatcgtcag atgagtgcca ctctgtcgcg acagtgactt
     5941 tcacgagagt gattttcaca tactaaaata ataatcagcc atataaccac gtaattaaat
     6001 taccggatgg ccattccggc cagatccgac ttttatgtta ttccgcagtt tccggaagtg
     6061 taccacggtc aggaagtaag cgaagcactg ttttctgctg ctgcgcgccg ggtcacgggg
     6121 caggggaggg acacaacatc tagcgtcatc gtcagccaga aacaccgcta catcttgtgt
     6181 ttccgggccg ctgcgcgccg gagccgttcc ggcagatccg gaacttggag ttttcggatc
     6241 tcaggaaaag aaaggagtga gggataaaaa ctgacattat taaaaatata aaagcaatgc
     6301 ttaaaaagca taaaagcact ttttgtaatt actgctagta ctacaagaag aatctttagt
     6361 ttgaggcggc gtttatgaag gtgaccgagc cggacgcgat tccagcatta gctgatctgc
     6421 tcacactgaa cggggagaca ggctgccgtt ctgctcagag aagcggcagc cgtggctaaa
     6481 gcattaggtc ttcaaaattc agcgtatggc tgtgcggctt tttgcggaaa gacagctcgt
     6541 ttatacgaag cttaagtggc atagggcaga tcacgccact gaatatgcag gtgccggttg
     6601 caagcgttgg aatagattct tcagtcatgc ggtctatgta ggaaacggat ttttcaatag
     6661 catacagatc gttctgattt atcaaccggt gaatgaaata gttatgtgcc tgagaaatga
     6721 tagtcgggga gatatcattt ggtcgctgac tggatatcgt cacaaagacg ccaaattttc
     6781 tgccctcctt aattatctct tcaaacgttt cgagccgata atccttccag ctttctgatt
     6841 ccctgaacga ggtgttcgaa aggatattgt gtgcttcgtc tatgatgaga tggagagtgg
     6901 acggtacctt atccattttt tttgctgaat aggcccattt ggccattaaa agtggtagcg
     6961 tttttttcat ggtcagattg accatattaa ggttcaggac aacaaagttc gtttctgccc
     7021 agatggttcc gccggatgca gtattgaaaa ttttacgaat atcttttttc agtccgctca
     7081 ttcggttgat gacaggagaa agatgttcag gatttgagcg acttgaaaga tattcaataa
     7141 ttagctgaac atacatatag tccagcaact cttccattat atcttcggga aattcataat
     7201 tctgagccct ctggtacata ttgcactgat gagtattttc ttcattagaa aagtaaacac
     7261 ctgtcttagt tcgccatacg ccgccgttgt tataaaaaaa ttcaatatct gctatcaggt
     7321 cttcgtcctt aagtacggga cggaataaat caatcaggtc gtcacttttt ttcttttcgc
     7381 aaccaaacag agtttcggtg acccgccgtt tcagaatttc acgaaaatat gactgagggt
     7441 tcagcttcga ctccactcgc tttttgaatt caagtactcg cttcaggaaa ggtttctgcg
     7501 ttttgtcggt ggcatccgtc aggacagaga gaatctcatg ctcaagcagt atctcagcag
     7561 gcatcggaat gcgatcaccc tcttcatcat gcgtgctaag attgtaaaca accttgtcgc
     7621 gcgtaatgca acttctccca ccatattcac cattgaaatc aaataaaaga aaccgtgacc
     7681 gacttctgaa tccttcgcct agtaggtttt tcagggcctc atagccatgc tggtaaagcg
     7741 cggccagagt attggacttg ccgctgccag tattaccgaa gatggcgatg tgtgagttga
     7801 gaaggccgct tatcgggaga gtgatatcaa tatcttcgag atcggtgcgc gaaaaattca
     7861 gcccagactc gcccgctggc gcgatcgagt ggataagatg aagttgttcc tcagacatca
     7921 gaaaaacttc attgccgata aggggtaact cgcgtgttcc gccagtaaag cgcccgttcc
     7981 ggtcaatgta gcctgccagt gaggctgtaa gatagcgtcg gaagcgaagc gaatcgcttc
     8041 cgctaccaac aggtgatttt tcctcgacaa tcttctcggt ttctaccttt gcaatcagac
     8101 tcatgaagcc ttttttgact tcgatgaaac tacctactga aacatttttg agcaccttac
     8161 cgtgatagaa aaggtcactc agatttttat ttttatcgac aagcacgctg agtgttctgc
     8221 ccgatacttc acgaacctca ccgatcctta atactgcttc ttcgttaaca aaagcggagg
     8281 tcatttcata cctccaagaa agctggttat aatttcattc atctttttga agtccaacgg
     8341 agctccagga gtaaaaacca catcaacgtt ggaataatct cggaatttac caagaaatag
     8401 gtctttagcc gcctcgttgt aagcgaatat aacaattttg agcgtggcgt ttcgtagcgc
     8461 ttttttggta aggctttcaa tatgctcatc cgcaaaagaa aatccgaaaa ctataagcaa
     8521 agagccttct ttatccagct catttgaata agtccgtagt agatcgtaat acacgttttc
     8581 aagtaaggtt tcacgaaatt tatcctttcg cggcagaacc agttgatgtg acataaccca
     8641 gtcctgcttc tcctttggtg tattgaacgc aactggcttc atatccttaa tggaataata
     8701 gatttcctta tcatagctat gccaggaaag ggaaccatgc agcttgatga gattcaccgt
     8761 aggtagttcc acgctgtaat tataaaggtt tccggttgcg tgtatggtct gataaaaaca
     8821 tttggcatcg aatactgtcc ggttgtaaat atcagcgcgc tgacggaatc catcattcag
     8881 aatgacgttg ttatttttaa ccgccgcatc ctcaatgaac aaatcatagt tagtcgtaaa
     8941 aaggttgatg cgccgcggta gcaatccagt ccgccgcctc gttagaagca tttctaatgc
     9001 ccgcatgagc ttcgcgtagt tgttttgtgt cgatacgaca tcatctatta aagtaggaag
     9061 gattacctct gcgggcctgc ttcgcttcag gaggacgttg tttgccttcc atacattgtc
     9121 cagaaaagac tcagatttac tgaagtattc atcatcattt ccggcgcgga ccagagcctc
     9181 aagctcgctt tcaatatcac ctaacacgct gattgcaggc agtgatgctc ctgagccaat
     9241 gatgaaattg atgtttgctg actgaaatat gcgttcaaag tattcacgat ctctgtcctg
     9301 cccgtagtaa gcccgataag tcgccacgct gtgcctttcc ttaaatatcg tagataagat
     9361 ttatcttaca tgtttcaaca agtgatgcat cctgtttaaa tttcattctc tgactcatat
     9421 acgaacgtag ctaaacgaat caggtaggca gtttcggtga tgctgccaac ttactgatta
     9481 agcgtatgat ggtgtttttg aggtgctcca gtggcttctg tttttatcag ctgtccctcc
     9541 tgttcagcta ctgacgaggt ggtgcgaacg gcaaaagcac tgccgaacat cagcgctatc
     9601 tctgctctca ctgccgtaaa acatggcagc tacagtttac ttacaccgcc tctcaacccg
     9661 gtacgcacca gaaaatcatt gatatggcca tgaatggcgt cggatgtcgc gccagtgcac
     9721 gcattatggg cgttggcttc aacacgattt tacggcactt aaaaaactca ggccgtagtc
     9781 ggtattctcg cgcatacagc cgggcagtga cgtcatcgtc tgcgcggaaa tggacgaaca
     9841 gtggggctac gtcggggcta aatcgcggca gcgctggctg ttttacgcgt atgacaggct
     9901 ccggaagacg gttgttgcgc acgtatttgg tgaacgcact atagcgacgc tggagcgtct
     9961 tatgagcctg ctgtcaccct ttgggtgata tggatgacgg atggctggcc actgtatgaa
    10021 tcccgcctga agggaaaact gcacgttatc agcaagcgat atacgcagcg aaatgagcgg
    10081 cataacctga atctgaggca gcatctggca aggctgggac ggaagtcgct gtcgttctca
    10141 aaatcggtgg agttgcatga caaagtcatc gggcattatc tgaacataaa acactatcaa
    10201 taatttggag tcattaccta cgatgagatg tgcctgcggg gtaaacctaa aatggtggcc
    10261 attggcgcgc tgatgcggaa actggtgcac tggtgttatg gcgtcctgaa gaccggaacc
    10321 gtttttaatg acgaaggtct gaaacaagta ctgtcaacct gactatacct ggctggcatt
    10381 aaactcaatg taacgctcac agcagtaagt gagcgcagtc cgctatgagc gatctacgga
    10441 cattgctagc agcattaggt gtgagtcaac agggagcttg tcagctcacg ctaccggagg
    10501 atatgataaa tggggaattg agaaatttaa atttcaatat aaacaaacaa ttatcttctt
    10561 agcgtacgtt tccgttccat taccctcaaa cccaaataag ataattctgc cagaagcaaa
    10621 acaatcagga tgtgagatag aaaatgtata agattgatcg gcaaaacaat agcctcaagt
    10681 cgctcatgga agtctctttt agcagtcttg gttttcgcga acgcgatcat ttgcaagagt
    10741 ggctggcaaa caatcctcaa gcgttgacta agaaagatga taaagaggac gaacttttaa
    10801 ttattcagaa agagtttgct ggttttgatg agactaacga acgtctcgat ctgctggcta
    10861 tcgacaaaaa aggcaacttg gtcattatcg agaataaact tgatgattca gggcgtgacg
    10921 tggtctggca ggcgctgaag tatgcgggtt actgcgccaa ccttcgtcag gaaagcgttg
    10981 tcgaaatttt tcagctttat cttacacaac atgaaccctc ggaaatccgc cctgcggcag
    11041 aagttattgc agaatttatg ggctgggaaa gtttgaaaga aggtgtgctc aatcgaaaag
    11101 ggacacagcg cgttatcatg gtagcggcga atttccgcaa agaagttacc aatactgcac
    11161 tatggctaat gcagtttggc atccgagtgc aatgcttcaa agcgacgccg tacctctttg
    11221 ccgaggatgt ttttgtcgat atacggcagg tcattccgac tcctgaagcg gaatcctaca
    11281 tgattggaat ggcgcagaaa gaggcagaag agcagtccac ctcaagcagt agcgaactgc
    11341 aacaacgaca ttatttacgc cgtgagttct ggtcgttagc actggaaaaa ttccgtacca
    11401 gcacatgttc attatttaac aaccgagcac ctacgacaga ccattggctg gcagcgggtt
    11461 cgggggttag tggcgtgcct tttgaagtga tcttctcgca aaaagatgct cgcattcagc
    11521 tcaatatttc acgttcagat gcggtagaaa atacatggct gtttgagcgt ctgtcagagc
    11581 gcaaaacgca tattgagtcg cagtttggtg ggatgctcaa ttggcgacta ctgcctgaga
    11641 gaaaaagctg ccaggttgtt tgtgcaaaag catttgacgg cggaaacaaa gaactttggc
    11701 ctgacatcat tagctggatg attgatggta tgacccgtct ggaaaaagca attcgcccga
    11761 gcttacagga gctggcggtt gagctgaaaa agtcaggtct gatcaccgaa ggtggggacg
    11821 agtagtatta agtagagtga ccctgacccg tgatccacgc aaactgtaat taacaacttc
    11881 cgctcctggc acaaagcaga cgttaaagtc tacacttcct gatgccgcgt cagcggcatg
    11941 gaggcgccag atgaggttac atgtgtctgt ggagtcaaat ggcgccgaaa gcccggcgta
    12001 gccggttgcc gggctataaa ttctgccacc ctaccccctg ccctgattag ccttaacccg
    12061 ctaacagcaa tgaagaagtc aaagtaatcc cttttaaccc cggtgagcgg gctttacggc
    12121 gtttacgacg taaagggcgt gatttccggg gccttagcgg cggcagcttg ctgctgacgc
    12181 ttagggggat gttcatcaac tatctaagcg acaccaggga acttaacggt aagcgtacag
    12241 cgagagccgt ctggtcataa cctgatgtat tcgacaaagt ggtgtccacc aaataagtag
    12301 tgggaaccaa agtgtcagat atgcagaaaa atgtgactcc cggcaggcgt aagggctgcc
    12361 ctaattattc tcctgagttt aagcagcagc tcgttgctgc ctcctgcgaa cccggaatat
    12421 ccatctcaaa actggtgctt gaaaacggca tcaacgctaa tttgttattt aaatggcgcc
    12481 agcagtggcg cgacggaaag ctactgttac cttcctcaga gagtcctcag ctacttcctg
    12541 tgactctcga tgccactgcc gtacagccaa aatcgctcgc ggaagacccg gggctcagta
    12601 tcagctgtga ggtaacgttc cggcacggga cgcttcgcct caacggtact gtcagcgaaa
    12661 agttcctggc tctgctgata caggaactga agcgatgatc ccgttacctt caggcacaaa
    12721 aatctggctg gtagccggga tcaccgacat gcgcaacggc ttcaatggtc tggccgcaaa
    12781 ggtgcagaca gcgctgaaag atgacccgat gtccggccac gtcttcatct tccggggacg
    12841 cagcggcagt caggtcaaac tgctgtgggc caccggcgac gggctgtgcc tgctgacaaa
    12901 gcggctggaa cgtggtcgct tcgcctggcc ctcagcccgc gatggcaaag tgttcctgac
    12961 cccggcgcag ctggcgatgc tgatggaagg tatcgactgg cgacagccaa agcggttact
    13021 gacctccctg accatgctgt agctctcttt aatcctggtt gtcgcagaat aagcctggta
    13081 aaatacgggc ttatgaacga cgcctcttct gacgacatcc ttctgctgaa acagcgcctg
    13141 accgaacagg aagcgctgaa ccgtgctctg ctggaaaaac tggccgatcg tgaacgcgaa
    13201 atagaccatc tgcaggcgca gctggataag ctgcgccgga tgaacttcgg cagccgttcc
    13261 gaaaaggtat cccgccgtat cgcgcagatg gaagctgatc tgaaccggct tcagcaggaa
    13321 agcgatgccc ttaccggtct ggttgatgac cccgcggtgc agcgcccgct gcgtcagacc
    13381 cgcacccgta aaccgttccc cgaatcgctt ccccgtgatg aaaagcggtt gttacccgca
    13441 gagccctgct gtccggagtg tggtggttcg ctgaattacc tgggtgagga tgccgccgaa
    13501 cagctggagc tgatgcgcag cgccttccgg gttatccgta cggtgcgcga aaagcatgcc
    13561 tgtcgtcggt gcgaccgcat cgtgcaggcc ccggcgcctt cgcgccccat cgagcggggc
    13621 atagctggac cggggctgct ggcccgcgtg ctgacctcaa agtatgcaga gcacacaccg
    13681 ctgtatcgcc agtctgaaat atacggccgc cagggcgtgg agctgagtcg ctcactcctg
    13741 tcgggctggg tggatgcgtg ttgccggctg ctgtcgccgc tggaagaggc gcttcgaaac
    13801 tatgtgctga ctgacggcaa gcttcatgcc gatgacacgc cggtgccggt gctgctaccg
    13861 ggtaataaga aaacgaagac ggggcgctta tggacgtacg ttcgtgacga ccgtaacgcc
    13921 ggatccgcgc tgacgccggc ggtgtggttc gcttacagcc cggacagaaa aggcatccac
    13981 ccgcagaccc atcttgccgg cttcagcggt gtgctgcagg cagatgcata tgccgggttc
    14041 aacgagctgt accgcgatgg gcggataacg gaagctgcct gctgggctca cgcccgccgt
    14101 aagctccacg atgtgcacgt tcgcacccca tcagcgctga cggaggaagc cctgaaacgg
    14161 atcggcgagt tgtatgccat cgaggcggaa ataaggggaa tgccggcaga acagcgactc
    14221 ggcgaacgtc agcagaaagc taaaccgcga ctgaaatccc tggaaagctg gctgcgagaa
    14281 aaggtgaaaa ccctgtcgcg acactcagag ctgacaaaag cgttcgcgta cgccctgaac
    14341 cagtggccgg cactggcgta ctatgcaggc gatggctggg ctgaagcaga taataacatc
    14401 gcagaaaatg ccctgcggct ggtcagtctg gggagaaaaa actggctgtt cttcggttct
    14461 gaccacggtg gtgagcgggg agcactgctg tacagcctga tcgggacatg caaactgaac
    14521 agcgtggagc cagaaagcta cctccgctat gttcttgacg ttatttctga ctggccggtc
    14581 aatcgggtga gtgaactgct cccctggcgc gtagcactgc cgactgaata acacatcccc
    14641 gtcaatacgg ctctcgctgt acgcttaccc tgtaacagcc tttctggctg tttgtatata
    14701 attatgaaaa aatggtgagt agagtttcag ggtaacaggg gatgcttatg tcggttttcc
    14761 acaactggct acttgagatc gcatgtgaga attacttcgt ctacatcaaa cgcctttccg
    14821 ccaacgatac cggcgcaaca ggtggtcacc aggtagggct ttatatccct tcaggtatcg
    14881 ttgaaaaact gtttccgtct atcaaccata cccgtgaact gaacccttcg gtttttctca
    14941 ccgcacatgt gtcatcgcat gattgccctg acagcgaagc ccgggcaatt tattataaca
    15001 gccgtcattt tggtaaaacc cggaatgaaa aaaggattac ccgctggggt agaggcagcc
    15061 cacttcagaa tcctgaaaat acaggggctc tgacgctact ggctttcaag cttgatgagc
    15121 aaggggggga ctgtaaggaa gtaaatattt gggtatgcgc cagcactgat gaagaggacg
    15181 tcattgagac cgctattggt gaagttatac ccggagcgct tatatccggc cccgcaggac
    15241 agattctagg cggactatct ctacagcaag cgccagtaaa tcataaatat attctacctg
    15301 aagactggca cctgcgcttt ccgtcgggaa gtgaaattat tcagtatgca gccagccatt
    15361 atgtgaaaaa ttcccttgat cccgatgagc aacttcttga ccgccggcgc gtggagtacg
    15421 acatatttct attggttgag gaactgcatg ttctggatat catccggaaa ggatttggct
    15481 ctgtggatga atttattgcg ctggccaatt ctgtcagcaa tcgccgtaaa tccagagccg
    15541 ggaagtcgct ggaactgcac ctggagcatc tattcattga gcacggcctg cgacactttg
    15601 cgacgcaggc catcacagaa ggtaataaaa aacccgattt ccttttccct tccgcagggg
    15661 cttaccacga tactgagttt cccgtagaaa atctgcgcat gctggcagtc aagactacct
    15721 gtaaggatcg ctggcgtcag atactgaatg aggccgataa aattcatcag gtgcatctgt
    15781 ttacactcca ggagggagtt tctctggctc aatatcggga gatgcgggag tcgggtgtca
    15841 gattggtcgt gccatcatct ctgcacaaaa aatacccgga ggcggtgaga gctgagctaa
    15901 tgacgctagg tgcgtttatt gctgagctga cagggcttta cgcagatatt ccatagatta
    15961 tctcccggca taaataccgg gaggagcgat cagattcgtt caaccttgca cgaatcggca
    16021 taaaccgctt tcaggatata aggttcaagc agtttggcta cggcttcaaa cacgggcacc
    16081 actacggagt taccgaactg cctgtacgac tgagtgtctg acacaggaat gcgaaaaggc
    16141 ctgccatcta ctttttcaaa acccataagg cgcgcgcact ctcgtggagt cagcctgcgg
    16201 ggccgatgcg cctgattttc ttcgttcgcg aagtctgttt cacctgtggc catatcccag
    16261 ccacggtcta tcagaatttc agacccgtct ttgtgatagc gagcagaaag cgtacgggca
    16321 atgctttctt tattttcagg attaacgagg ccaaaaccga atccgttacc cttagctgcg
    16381 tgctttttgg cgtagttata gagatactcc cagagtttcg gcgtcagtat atatttgctg
    16441 tcaaccacgg gttccagcag ttcgccaaat gacggacgct gttccggata aaaacgacta
    16501 atatcgcgca gggtaaagcc ctggtgaatg ttcagatcac gacggaaacc gaccaaaacg
    16561 atacgttctc ggtgctgagg taaaaagtgc tttccgtcga taactttagg atcgtttttg
    16621 cccatctcag ctgcatccgc aacttcatag cctagttcgt cgagggtatc catgatgact
    16681 ttaaaggttt tacccttgtc atggctcttc aggtttttaa cgttttcaag aacaaagatg
    16741 gcaggttttt ttgcgcggat aatacgcgcc acatcgaaga aaagcgttcc ctgagcctca
    16801 cattcgaaac catgcgcgcg cccgagcgag tttttcttgc ttacgcccgc aaggctgaac
    16861 ggttgacagg ggaaacctgc tagaagtaca tcatgatccg gcacatgctc attaatgtaa
    16921 gcataggcat cgttttcagg tacttcaggt ttatcactga gcgtgacttc ccgaatatcg
    16981 agattgaaag tgtgttcctg aggatcgtta aaccagttag ctttatatgt gcgcacagcc
    17041 tctttattcc attcactggt aaaaacgcac tggccaccga tggtttcgaa gcccttccgt
    17101 atacctccaa tcccagcaaa caggtcaata aaccggaagg catagtcagg gtgatgtgca
    17161 ggcgcttccg gaagcatttt tcgtagaagt tcctcttcgg ctaacgtcag cgccttaggt
    17221 gagcacttac cattaatcca gcgattaaga gtctcgcgac tccactcatt tttaccaact
    17281 tttctaagca gttcagccac gtacttctgg tcatagattt ccagcacctg cccgagcagc
    17341 tttttatcat tttcctgtcg cagttgttct tccgcttctg ctttctcaag cagatcctgc
    17401 gccagtaatt caaattcaga catattgcct ccattgggtc ttatgggtga aactgtatca
    17461 ctcatttgac ccagattgaa tgtttttatc tggatattta aacaggttta ttgttaggtg
    17521 atgctgccaa cttactgatt tagtgtatga tggtgttttt gaggtgctcc agtggcttct
    17581 gtttctatca gctgtccctc ctgttcagct actgacgggg tggtgcgtaa cggcaaaagc
    17641 actgccggac atcagcgcta tctctgctct cactgccgta aaacatggca actgcagttc
    17701 acttacaccg cttctcaacc cggtacgcac cagaaaatca ttgatatggc catgaatggt
    17761 gctggatgcc gggcaaccgc ccgcattatg ggcgttggcc tcaacacgat tttacgtcac
    17821 ttaaaaaact caggccgcat tcggtaacct cgcgcataca gccgggcagt gatgtgattg
    17881 tctgcgctga aatggacgaa cagtggggct acgtcggtgc taaatcgcgc cagcgctggc
    17941 tgttttacgc gtatgacagg atacggagga cggttgtggc gcacgtattc ggtgaacgca
    18001 ctctggccac gctggagcgt cttctgggcc tgctgtcggc ctttgaggtc gtggtatgga
    18061 tgacggatgg ctggccgctt tatgaatcac gcctgaaggg agaactgcac gttatcagca
    18121 agcgatatac gcagcgcatt gagcggcata acctgaatct gaggcagcat ctggcaaggc
    18181 tgggcaggaa gtcactgtcg ctatcaaaat cggtggagct gcatgacaag gtcatcgggc
    18241 attatctgaa cataaaacac tatcagtaag ttggagtcat tacctgactc tagatagtga
    18301 ctaaactcac aattgttaat actcacagaa cgggtatcaa atggagctag aatcttaagg
    18361 gcgaatggag caaactgaga taaatattta gataaggtct ttagataatt aaggaaacgc
    18421 taatgagccg tcttaaccct aaatcaacaa ctttaagaac cctttttctc cgttcgggaa
    18481 atcaatgtgc ctttccagga tgtgatgtgg aattaattaa ttcttacggc cagtatgtcg
    18541 gaaatgtctg ccatattgaa gcagctgaag tcggaggaga gcgttataat aagtcacaaa
    18601 cagatgaaga tcgtcgagct tatagtaacc taattcttct ttgtgcaaat catcacaaag
    18661 taactgatga tgtagatatg taccctgtac aagttttgca ttcaatgaaa acgacgcacg
    18721 agcgtacggt ttatggaaga aatatcgcag agaacaaagt tacagctttc gtcaattcaa
    18781 cacatggtga aacggtaaat ttacctcaaa atctatacaa agttcgaaac tcaatcttag
    18841 aaattttccg agaagaggca ttttctggat tagttgatca tgcgagaaat tatttttctc
    18901 attttgtcgg agttcctaaa gcaactcgta cactttacgc tcaaatcctt ttgatttcag
    18961 aaagcgctga ccactgtacg attattgata ttcgaaaagt accgcaattc cttggtgtgg
    19021 caatggaatt tttacatgta cattacacaa tacttgaaaa tgcagggttg cttagtgagc
    19081 aaattataga tgacgatgtc catccagtcc gcctctatcg cgtattcact acttttgatc
    19141 gaaatgacat gcaggcttgg ttgttacaaa gtataagaaa ttattatctg caaagccaac
    19201 gacaaaccga ttttgtggaa ctggtaactg atcttaactt taaccttatg gattcataat
    19261 tacttatttt tatagaagaa tattccgttt tgcgagaatg gagcctttgc ttatagtttc
    19321 cagctggtta atgcgaagaa gtcaaattgc aggcactggg tgagtaagag cctgaaaggg
    19381 tcctcagtgt cgtttgaatc ctcttaataa tctaatgcgc tgaccggctt tgttgaataa
    19441 atcgaacttt tgctgagttg aaggatcaga tcacgcatct tcccgacaac gcagaccgtt
    19501 ccgtggcaaa gcaaaagttc aaaatcacca actggcccac ctacaataaa gccctcatca
    19561 accgtggctc cataactttc tggctggatg atgaagctat tcaggcctgg tatgagtcgg
    19621 cagcgccttc ttcacgaggc agacctcagc gctattctga ccttgccatc acgactgtgc
    19681 tggtcattaa acgcgtattc aggctgaccc tgcgcgctgc gcagggcttt attgattcca
    19741 ttttttctct gatgaacgtt ccgctacgct gcccggatta cagctgtgtc agcaggcggg
    19801 caaagtcggt taatgtcagt ttcaaaacgc ccacccgggg tgaaatcgca cacctggtaa
    19861 ttgattccac cgggctgaag gtcttcggtg aaggcgagtg gaaagtcaaa aagcatggcc
    19921 aggaacgccg ccgtatctgg cgtaagctgc atctcgccgt tgacagtaaa acacatgaaa
    19981 tcatctgcgc tgacctgtcg ctgaacaacg ttacggactc agaggccttc cccgggttaa
    20041 tccggcaaac ccaccggaaa atcaggtcag ccgccgccga tggcgcttac gatacccggc
    20101 tatgtcacga tgaactgcgg cgtaagaaaa tcagcgcgct tatccctccc cgaaaaggtg
    20161 cgggttactg gcccggtgaa tatgcagacc gtaaccgtgc agtggctaat cagcgaatga
    20221 ccgggagtaa tgcgcggtgg aaatggacaa cagattacaa ccgtcgctcg atagcggaaa
    20281 cggcgatgta ccgggtaaaa cagctgttcg ggggttcact gacgctgcgt gactacgatg
    20341 gtcaggttgc ggaggctatg gccctggtac gagcgctgaa caaaatgacg aaagcaggta
    20401 tgcctgaaag cgtgcgtatt gcctgaaagc gtgcgtattg cctgaaaaca caacccgcta
    20461 cgggggagac ttacccgaaa tctgatttat tcaacaaagc ccagcgccgc aaatactctg
    20521 accgattacc acctgaaacc aggtctatat aggccaaaag ttcatctgat acttttgcgg
    20581 ttattgttgg cattcagtcc tcactttgtg cattttttaa acgaaaaaag ggtgtctaat
    20641 acggtgaaat catagtatta ccaaagtaat aaataaaaaa tgttttaaat cagtaagtta
    20701 gattagattt gtaatacctg ggtaataccg cagcatggtt aaatttggtt ttttttcttt
    20761 taaatcagtg agatagcgtg atttatcacg ctgcgttagg tgtatagcag gttaagggat
    20821 aaaaaatcat ctttttttgg tagggcgatc tccgtaggtt aagggtcatt tggctaaaaa
    20881 gcgtcctatt ctttgatggt catgcttgca tgaccatctg agcaaccaaa aactacagat
    20941 aaactacaga taaactacaa aaaacgtttt gccttagtgt tggaagacta caaatagact
    21001 acaataaaac tacaaaaaaa ctacaaaaaa cgtgacagac tacaaataga ctacaagaaa
    21061 actacagata aactacaaaa ctcgattgac cccttcttac gagtgttgta gagtcatttt
    21121 catacaacgg agggggttat gaataaacca gcagatctga aaccccgcaa cttatcggct
    21181 gctgtcagat tgcgcctaaa tgaaatcgag aactggctgg acagagggct aacgcggcat
    21241 gaaattgctg aaatcctcga cagcgaatac agcttttcgg taacagccaa agggcttgag
    21301 atggcactgt atagaacgcg gcaaaaccga aaaaatgtat tgcacaatac acatgataag
    21361 agtagcgcga agggtgcagc ggaaagtgta ttgcacaata cacaaccgtc tgagcctgaa
    21421 gcgcaggaaa gtgaaaaagc agagagtccc ggcattattg ataaagaatt cttcaataaa
    21481 atcggtgaga atttcgaccc taagaagttc aacaaaaaat tctgaggtga tttatgaaag
    21541 tagcggtaat taattacagt ggcagtgttc gtaaaacctt aatttcatct tacctgttag
    21601 ccccgcggct gactggtgca aagttctatg cggtagagac tatcaaccag tctgcttccg
    21661 atctgggtat tgaaaatgtg accagtttta aaggtgacga cttctcacgt ttgattgagg
    21721 ggtaatgact ccaacttact ggtagtgttt tatgttcaga taatgtccaa tgactttgtc
    21781 atgcagttct cccttcaggc gtgattcata aagcggccag tcatccgtca tccataccac
    21841 gacctcaaag gccgacagca ggcccggaag acgctccagc gtggccagag tgcgttcacc
    21901 gaagacgtgc gccacaaccg tcctccgtat cctgtcatac gcgtaaaaca accagcgctg
    21961 gcgtgattta gcgccgacgt aaccccactg ttcgtctatt tccgcgcaaa caatgacgtc
    22021 actgcccggt tgtatgcgtg agtttaccga ctgcggcctg agaggcggtg taagtgaact
    22081 gtagctgcca tgttttacgg cagtgagagc agagatagcg ctgatgtccg gcagtacttt
    22141 taccgttacg caccacgcct tcagtagctg agcaggaggg acaagtgatg gagatggaag
    22201 ccactggagc acctcaaaac caccatcata cactaaatca gcaagttggt agcattaccc
    22261 agaactggac agaatagtct gtatgtctaa cttctggcca cagatataat cgagccagca
    22321 gtgctcgccg cagccgagcg acagggcgaa gccccgagtg agcgaggaag caccatggaa
    22381 cagtactcat aaattctgca tacgctcaat gcctgcaaaa tcacctccca taggggttat
    22441 ccacttatcc acggggatat ttttataaga tctttttaaa tagttgttag atttttattt
    22501 ttagaatgcc cacaggcctt tatccatgcg ggttccagag agggatctgt gacaaaacgc
    22561 cctttcagtg tgacaaatca ccctcaaata gccgccattt ctgtgacaag ttgcccttaa
    22621 ccctgtgaca aattgccctc aggaagcgtt gcttttcaca aagttatcca tccctgttga
    22681 ctctgtttta tgaagtgtga caatcttaaa gtctgtcaca cttcgcatgg acctgtcatg
    22741 gcggaaatag cggttataaa ccataaaaaa cgtaaaaata gcccgcggat tgtccagtct
    22801 aacgagctga ctgaggcggc atatagtctc tccagggatc aaaagcgtat gctgtatctg
    22861 ttcgttgacc agatcagaaa atccgacggc tccctgcagg aacatgacgg catctgcgaa
    22921 attcacgttg ctaaatacgc tgaaacattc gggctgacct ccgctgaagc cagtaaggat
    22981 atacgacagg ctttaaaagg ttttgcgggt aaggaagtgg ttttctatcg ccctgaagag
    23041 gatgccggcg atgaaaaagg gtatgaatcc tttccctggt ttattaaacg tgcgcacagc
    23101 ccatccagag ggctttacag cgtacatatc aacccatatc tgattccctt cttcatcggg
    23161 ttacagaacc ggtttacgca gttccggctc agtgaaacaa aagagattac caatccgtac
    23221 gccatgcgtt tatacgaatc tctgtgccag taccgtaaac ctgatggctc aggtgtcgtg
    23281 tccctgaaaa tcgactggat catggaacgc taccagctac ctcaaagtta ccagcgtatg
    23341 ccggactttc gccgccgttt cctgcaggca agtgttgacg agatcaacag ccggacacca
    23401 atgcgccttt cttacatcga gaaaaagaaa ggccgccaga cgacgcatat cgtattttcc
    23461 ttccgtgata taacctccat gacgattgaa tagttgaggg ctatctgtca cagatttaag
    23521 ggtggttcgt cacatttgat ctggaaagtt gagggtgatt tgtcacagtt ttgctgttcc
    23581 ctccctggca tcctgcgctt actcatagtt tttttggctg taaccggtag tggagccaga
    23641 attgagggca atttgtcacc ctatcctgag ggtagtttgt cacactagat tttctccctc
    23701 ttcccgggta atggtgccaa cttactgatt tagtgtatga tggtgttttt gaggtgctcc
    23761 cgtggcttcc atctccatca cttgtccctc ctgctcagct actgaaggcg tggtgcgtaa
    23821 cggtaaaagt actgccggac atcagcgcta tctctgctct cactgccgta aaacatggca
    23881 gctacagttc acttacaccg cctctcagcc cggtacacac cagaaaatta ttgatatggc
    23941 catgaatggc gtcggatgtc gcgccagtgc acgcattatg ggcgttggcc tcaacacgat
    24001 tttacgacac ttaaaaaact caggccgcag tcggtaaact cacgcataca accgggcagt
    24061 gatgtgattg tctgctctga aatggatgaa cagtgtggtt acgtcggcgc taaatcacgc
    24121 cagcgctggt tgttttacgc gtatgacagg atacggagga cggttgttgc acacgtcttc
    24181 ggtgaacgta ctatggccac gctggagcat cttctgagcc tgccgtcgga ctttcagggc
    24241 gcgtggttcc ttttaaacac cagctctgta tctcttttaa agatccttca ataaatcctg
    24301 taaacacata acctgttcat cgcctgccct gtggacaggc tcgggagaat gcccgccctt
    24361 gcagcgacct gacggtcgcg ccggttcggc aacacctgag agagctccca tcgcttcgcg
    24421 acgggccccg accggagaac cacattagtt acagcattca aaaggaagtt aatcataaaa
    24481 ccggcgccgg tttgccggcc aggtgcccct ccccaccact gaaaagcgcc gccgcccccg
    24541 gccgaaggcc gggagtagtg tcgcttttaa tgatgggtgt tgtaactatt cttcttcatc
    24601 gctgtgggtg gagctgcggt cagttgtctg gtacacgctc gtaagcggcc ctgcggcccg
    24661 ctaacgcgga gatacgcccc gactgcggct aacgccttgt cgggaccact ccgaccgcgt
    24721 acagcagctt ctgtatcgtt tttagcgggt ttgttctggg cttagcagtg tgggggatta
    24781 ttacggctga agccgtaatg cttttttcgt cctcgcttcg ctgcgggggt ctcaggcgca
    24841 tggcgcctcc catgcgctga cgcgcatcaa aaacccgtcc cctgcgccac ttgtgtctga
    24901 cgcacgcgag agtccgctgc ggcaaaaaaa caagaagaga gctagacgaa ggtcgctcag
    24961 ctccccgtaa ttttttatat actcaccacg gggacattag atctgctttt gccaaaaaaa
    25021 cggctagttt tttctggatt tacccaaacc aaaggcaccg gcattcacta taaacgaggc
    25081 ctttctgatc ggcgtatcga tatcaaatat ggggttttca gcacgccttc tttcaaagta
    25141 cttatttctc tccgattcat ttttaaaagc gctacctgtc cttgcaatcc tctcctgaat
    25201 aagcatcttt tcatgctcag cctttttggt tgagttggcc ttagcgagat tcttttcaag
    25261 ggatttcgta tgctttttta tatgctttct caacctagct ttatggccaa atgagagttt
    25321 acatatcgga caagtgaata attcttccat aagcttcatg agtgtaaggg gaaggttata
    25381 tttaccatag cattccttgt ccgaactgcc atgcgatggt ccaccggggc aatgaggcaa
    25441 agccgttgtc tgtggaagca ctacgcggca tgatgagcgt cgccagttgc acaccggcaa
    25501 agacgtgaaa cacttttaac cggagccagt catgcgcgtt gccgaaagca tcatcctcga
    25561 tgccctcact cgcggaggat gcatcaaaac cttttaccgc atatcctcac ggcaggctgc
    25621 tgaatcggcc acgcggatac ctgaggggta tattctggag tcgcccggcg agcgggaaga
    25681 tattgtgctc tcgcgcgcgg actttcatgc gctggagaag ctgctggagc agaaggaaac
    25741 ctgggagcag gtggtcggtg tgacctgttt tggtggggca acatggcagc tgagaccgac
    25801 tgtacagagc tgaacaactg agatttaaga ccagggaatc agtaagactg aagggaggta
    25861 tctgttatga cgctgacaga aaaaacaggc catctggcat ggtgtgcact ggtcgcgctg
    25921 gcactggcca gacaggagca gggagaactc tctcccgcac aggaaaatct ctttctcacc
    25981 cgctggctcg cggcagcact gaagcaacgg cgattctcgc gcgatgtggc acaggatatc
    26041 gggtggttac tgaatcaggg gcgtttgctg ggtgtgagag ctaagctggc cgacaaactg
    26101 ggctatgtct ggcgctcctg cagcggcgag ttgactgaac agaacgacat gttccgcctg
    26161 acgtatgcgc tggaaacagc gaaagacatg ggctggaatt accgcgtaat gagcgacaga
    26221 gaatgggccg gacgatatgc tttggtactc aatcctggag taaacggtgt ttatctctta
    26281 cggacaaacc ttgatgccgc ttttgacgac aatggccaac agacaaatcc gctgacagta
    26341 cgtctgacag ggaacgtaac tgggataatg aaactgttaa atcgctgtgg ctggcaggct
    26401 gagcctgagt ctgatgcctc cctgccccac cagttttcac tgatggcccg gcagggagtg
    26461 ccaggaaagg gggattagtg gcggatttgt gccaggttat cttcagtcag accggtcatt
    26521 ttcatgacag tattgcggtc aatgccgttc tgcagcatgg tacgggcaat tttcagagtg
    26581 gcctgacgct caccttctga acggcctatt agcgtgtgct ccggtggttt gcacatgcgc
    26641 aaatttttca gcccaaaggg ggctaatcat cacggggatt acgttcaaat cccctgcgcc
    26701 ctcttgctgc ccattcagca ttgagtacca cgtaacgctc ccagcgttca cgcagctgtg
    26761 cgagctttag cggtacttct ttggtgacaa aggcttccgg tatttcaaag tcatcaagat
    26821 gcccttccag gtatacatgt acgccttcca acacatcaat cagagtgatg ttgttacttt
    26881 gttgcccttc aagaagcggc ccctgccagc tatgccagaa ggcctgatgg cgcagacagc
    26941 tttcgtcatt cgcgagcctc cataaatcca taaagattcc tcgtgcaact ttgaacggct
    27001 gttcatcaaa ctgttcgatg agaaagaaat aacacgggat cttgagcgcg ttaatacgcg
    27061 caatttcaat ttcagcatca cggcgcaagg caatcagatt gctaaagcgc gagcgcatac
    27121 aggcgacagg gttcaatacc cttacctttt cattcatttc aggcatgccg gggccggttg
    27181 cttctacata aaacggggcg gtatacaggt aaagcttttt cccctgaaaa tcagaacggt
    27241 caaagcctcc ggggcggtcg ataatatcca ccacatttgg ctcgtcaggc gcatccggta
    27301 cggcaaataa gcgtccatca tcccgtttga tatcgtgtgt atcctgatcg ataagcataa
    27361 actgcgcaag ggatgggggc tgaccgtctt tgttctccca cgtcttaacg ttgagcgttt
    27421 ttgctatagc cgcaatatca tctttccggg cgctgtagtc gcagtcaaca gatgtggtga
    27481 ggcgctcatc aggcaatctg tcgccgtatt gtgcatgata ataggatatc cagtattgca
    27541 cagcctgacc gccaactgtg ataacggcat gtttgaactg atcagcgttg cagatcagct
    27601 gctgatttag caggtacatc tgctcatagg ggggaataac gtcttgaaca ggcataaaaa
    27661 aaccatcagc gaatgatggt ttattgtgcc tcaaagttca ggatcaggca aaagcgatag
    27721 tatgagcgaa tttgctacta gctgacttac tgaagcggct tttcacggca ggtttgtaac
    27781 cggcacgacc acgcaaaacc tgcaccgcta cggcttcgta gcgttcatgc tgcttttgtt
    27841 tagcttgtac gggagacata attttgtacc tgacggtagt tataaacaaa taagttgcag
    27901 taactatacg tcacgaatct acgtcacgca atagag
//
