LOCUS       NZ_CP117205            27080 bp    DNA     circular CON 23-MAR-2024
DEFINITION  Staphylococcus aureus strain 2022QW-00133 plasmid p2022QW-00133_1,
            complete sequence.
ACCESSION   NZ_CP117205
VERSION     NZ_CP117205.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN32885235
            Assembly: GCF_028596045.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27080)
  AUTHORS   Johnson,J.D., Blankenship,H. and Soehnlen,M.
  TITLE     Long read genome assemblers struggle with small plasmids
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27080)
  AUTHORS   Johnson,J.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2023) Bureau of Laboratories, Michigan Department
            of Health and Human Services, 3350 N Martin Luther King Blvd.,
            Lansing, MI 48906, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2022
            Assembly Method                   :: Trycycler v. v0.5.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 153x
            Sequencing Technology             :: Oxford Nanopore, Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028596045.1-RS_2024_03_23
            Annotation Date                   :: 03/23/2024 03:27:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,782
            Genes (coding)                    :: 2,700
            CDSs (with protein)               :: 2,700
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 43 of 82
            Pseudo Genes (incomplete)         :: 37 of 82
            Pseudo Genes (internal stop)      :: 20 of 82
            Pseudo Genes (multiple problems)  :: 17 of 82
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP117205.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27080
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="2022QW-00133"
                     /isolation_source="nose"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="p2022QW-00133_1"
                     /geo_loc_name="USA"
                     /collection_date="2022"
     gene            1..984
                     /locus_tag="PQQ74_RS14165"
                     /old_locus_tag="PQQ74_14170"
     CDS             1..984
                     /locus_tag="PQQ74_RS14165"
                     /old_locus_tag="PQQ74_14170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1004..1293
                     /locus_tag="PQQ74_RS14170"
                     /old_locus_tag="PQQ74_14175"
                     /pseudo=""
     CDS             <1004..1293
                     /locus_tag="PQQ74_RS14170"
                     /old_locus_tag="PQQ74_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            1840..1989
                     /locus_tag="PQQ74_RS14175"
                     /old_locus_tag="PQQ74_14180"
     CDS             1840..1989
                     /locus_tag="PQQ74_RS14175"
                     /old_locus_tag="PQQ74_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(2157..2849)
                     /locus_tag="PQQ74_RS14180"
                     /old_locus_tag="PQQ74_14185"
     CDS             complement(2157..2849)
                     /locus_tag="PQQ74_RS14180"
                     /old_locus_tag="PQQ74_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2959..3153
                     /locus_tag="PQQ74_RS14185"
                     /old_locus_tag="PQQ74_14190"
     CDS             2959..3153
                     /locus_tag="PQQ74_RS14185"
                     /old_locus_tag="PQQ74_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4269..4886
                     /gene="cadD"
                     /locus_tag="PQQ74_RS14190"
                     /old_locus_tag="PQQ74_14195"
     ARG             4270..4883
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4905..5252
                     /locus_tag="PQQ74_RS14195"
                     /old_locus_tag="PQQ74_14200"
     CDS             4905..5252
                     /locus_tag="PQQ74_RS14195"
                     /old_locus_tag="PQQ74_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5409..5501
                     /locus_tag="PQQ74_RS14200"
                     /old_locus_tag="PQQ74_14205"
     CDS             5409..5501
                     /locus_tag="PQQ74_RS14200"
                     /old_locus_tag="PQQ74_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5673..6644)
                     /locus_tag="PQQ74_RS14205"
                     /old_locus_tag="PQQ74_14210"
     CDS             complement(5673..6644)
                     /locus_tag="PQQ74_RS14205"
                     /old_locus_tag="PQQ74_14210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6768..7187
                     /locus_tag="PQQ74_RS14210"
                     /old_locus_tag="PQQ74_14215"
     CDS             6768..7187
                     /locus_tag="PQQ74_RS14210"
                     /old_locus_tag="PQQ74_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7725..8570)
                     /gene="blaZ"
                     /locus_tag="PQQ74_RS14215"
                     /old_locus_tag="PQQ74_14220"
     ARG             complement(7729..8570)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8677..10434
                     /gene="blaR1"
                     /locus_tag="PQQ74_RS14220"
                     /old_locus_tag="PQQ74_14225"
     ARG             8678..10431
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10424..10804
                     /gene="blaI"
                     /locus_tag="PQQ74_RS14225"
                     /old_locus_tag="PQQ74_14230"
     ARG             10425..10801
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11068..11646
                     /locus_tag="PQQ74_RS14230"
                     /old_locus_tag="PQQ74_14235"
     CDS             11068..11646
                     /locus_tag="PQQ74_RS14230"
                     /old_locus_tag="PQQ74_14235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(11869..12054)
                     /locus_tag="PQQ74_RS14235"
                     /old_locus_tag="PQQ74_14240"
     CDS             complement(11869..12054)
                     /locus_tag="PQQ74_RS14235"
                     /old_locus_tag="PQQ74_14240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            12316..12990
                     /locus_tag="PQQ74_RS14240"
                     /old_locus_tag="PQQ74_14245"
     CDS             12316..12990
                     /locus_tag="PQQ74_RS14240"
                     /old_locus_tag="PQQ74_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13159..13730)
                     /locus_tag="PQQ74_RS14245"
                     /old_locus_tag="PQQ74_14250"
                     /pseudo=""
     CDS             complement(13159..13730)
                     /locus_tag="PQQ74_RS14245"
                     /old_locus_tag="PQQ74_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(14006..14800)
                     /gene="aph(3')-IIIa"
                     /locus_tag="PQQ74_RS14250"
                     /old_locus_tag="PQQ74_14255"
     ARG             complement(14010..14800)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14893..15423)
                     /gene="sat4"
                     /locus_tag="PQQ74_RS14255"
                     /old_locus_tag="PQQ74_14260"
     ARG             complement(14897..15423)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15420..>16055)
                     /locus_tag="PQQ74_RS14260"
                     /old_locus_tag="PQQ74_14265"
                     /pseudo=""
     CDS             complement(15420..>16055)
                     /locus_tag="PQQ74_RS14260"
                     /old_locus_tag="PQQ74_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16196..16870)
                     /locus_tag="PQQ74_RS14265"
                     /old_locus_tag="PQQ74_14270"
     CDS             complement(16196..16870)
                     /locus_tag="PQQ74_RS14265"
                     /old_locus_tag="PQQ74_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16927..17103)
                     /locus_tag="PQQ74_RS14270"
                     /old_locus_tag="PQQ74_14275"
                     /pseudo=""
     CDS             complement(<16927..17103)
                     /locus_tag="PQQ74_RS14270"
                     /old_locus_tag="PQQ74_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17117..17854)
                     /locus_tag="PQQ74_RS14275"
                     /old_locus_tag="PQQ74_14280"
     CDS             complement(17117..17854)
                     /locus_tag="PQQ74_RS14275"
                     /old_locus_tag="PQQ74_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17847..18776)
                     /locus_tag="PQQ74_RS14280"
                     /old_locus_tag="PQQ74_14285"
     CDS             complement(17847..18776)
                     /locus_tag="PQQ74_RS14280"
                     /old_locus_tag="PQQ74_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18892..19773)
                     /locus_tag="PQQ74_RS14285"
                     /old_locus_tag="PQQ74_14290"
                     /pseudo=""
     CDS             complement(18892..19773)
                     /locus_tag="PQQ74_RS14285"
                     /old_locus_tag="PQQ74_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19770..>20147)
                     /locus_tag="PQQ74_RS14290"
                     /old_locus_tag="PQQ74_14295"
                     /pseudo=""
     CDS             complement(19770..>20147)
                     /locus_tag="PQQ74_RS14290"
                     /old_locus_tag="PQQ74_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20205..20879)
                     /locus_tag="PQQ74_RS14295"
                     /old_locus_tag="PQQ74_14300"
     CDS             complement(20205..20879)
                     /locus_tag="PQQ74_RS14295"
                     /old_locus_tag="PQQ74_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21353..22819
                     /gene="msr(A)"
                     /locus_tag="PQQ74_RS14300"
                     /old_locus_tag="PQQ74_14305"
     ARG             21354..22816
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22918..23817
                     /locus_tag="PQQ74_RS14305"
                     /old_locus_tag="PQQ74_14310"
     CDS             22918..23817
                     /locus_tag="PQQ74_RS14305"
                     /old_locus_tag="PQQ74_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_050957275.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGYLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24303..24911
                     /locus_tag="PQQ74_RS14310"
                     /old_locus_tag="PQQ74_14315"
     CDS             24303..24911
                     /locus_tag="PQQ74_RS14310"
                     /old_locus_tag="PQQ74_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25157..25495
                     /locus_tag="PQQ74_RS14315"
                     /old_locus_tag="PQQ74_14320"
     CDS             25157..25495
                     /locus_tag="PQQ74_RS14315"
                     /old_locus_tag="PQQ74_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25500..25685
                     /locus_tag="PQQ74_RS14320"
                     /old_locus_tag="PQQ74_14325"
     CDS             25500..25685
                     /locus_tag="PQQ74_RS14320"
                     /old_locus_tag="PQQ74_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25912..26655)
                     /locus_tag="PQQ74_RS14325"
                     /old_locus_tag="PQQ74_14330"
     CDS             complement(25912..26655)
                     /locus_tag="PQQ74_RS14325"
                     /old_locus_tag="PQQ74_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22919..23814
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             21354..22819
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22919..23817
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.33"
                     /coverage="100.0"
     ARG             complement(14894..15411)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15718..16019)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7726..8570)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1350..1497
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..984
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1116..1285
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25913..26655)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa agggttagaa aacgatggtc tactcattca aaaacgacgt
      301 ggtttaaata aaccaaatat tctatattta atgaaaccta ttgtcacaga acgtgatatt
      361 tacaaaatag aaaaagaaga aaacgatgtt gaaccttacg gcgagaagga agttcgaaaa
      421 tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acgtccagaa
      481 gttcgaaaat cgaacactaa tgatactgac tttaatgaca ttgactttaa tgatactgag
      541 aataatgata tgaatgactt gaatgatata aagtacaaaa atgaaattag taatcattca
      601 aatcattcaa atcaatttac acataatttt gatgataaag aaatgctatt gcaagaattc
      661 ccagaacaac taactaatta tttattaaaa tatgattata gagatttaga aatcataaag
      721 gctgttattc ttaaagcaaa aaaatcattt aattcaaggc atgaagatat gcattacatg
      781 ttagaggaca ttgaggatga aatattaact tctttaaaaa gacttaaaaa agctatacat
      841 gataggggag ttaaaggcca aaaggaaaca atcaagtcaa tgcaagctta tttaatgcaa
      901 acaattctaa ctgaacttga agaaacacat gccctttata tgcgccgtaa aaacatgaaa
      961 caatataata tctttaatca ataattcaaa tgattttata acactcgaag agacatcaaa
     1021 atattccgtt aaatcatctg actttttaac tgatgacgac gaaaaaaatc aagaaattgt
     1081 aagtgattta gaaaaaggtt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa
     1141 acaaaagcat aaaattttaa acttagacga tgccgaagat ggtaatttga ttaatacaag
     1201 tgatgaagat aaaacgacag acgaagaaaa aaagcacatt caattaccgc aatttggaat
     1261 ttcgaaaagc aaaattatta tttaagacat tagtgataac tgatgtcttt ttttattgtt
     1321 tttctgtaaa aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag
     1381 tgtgacacta cagctttgta tgatatcact ttaaaataac ttaaaaccct tggaatgtct
     1441 ggccttgcca gatctatcat ttttgaatga tagcaaattt cccttatgct cttacggaga
     1501 ttttagagtt aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga
     1561 aaaacatggg gaagttttaa agtattttat gctaattttt aaatttgcat gtaaatgggc
     1621 agtatctaaa aaattagtca ctgattttgc tgaaattttt gtttgtgaaa ttagcatata
     1681 tttatttggc tcatatttgc gttttaagag actgtataga tttttaagta caaaacctat
     1741 atgatttgcc tctaagtctt caaaatgcct cttaaaatcc aaaataaaag tgtttaatat
     1801 tgtaataagg attgctattt ttataaaagg agagatatca tgaagattaa aactttcgct
     1861 acttttactc atcgtcaatt agataaacaa gttaataggt ttttaaagaa tgatattcat
     1921 gtattagaaa ttcaaacaca cagtaattgg ttatatattt cagctattgt tttttatgag
     1981 gataaataag gaacatcgta tttatgccga aaaaatttat tgatgttgag aagaaccctt
     2041 aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag
     2101 ttttgggatt gttaagggtt ccgaggctca acgtcaataa aacaattgga ataaaatcaa
     2161 cctacagagc atccagctgc aaatgcagtt ccgcaaactg cttcacatac accgccggct
     2221 attggattta cgattgccca tactccacag tagtgagcac atgcataaag tccagccata
     2281 ctacaagcga atgctttgcc gttccatttg aatcctgcat atgttaccgg tctgttttta
     2341 tcaacttttt cagccttata ttcaacgtaa tttttgttaa taagtatttt tccctctttg
     2401 ttttcagtca tacttctttt ttcggcaatg aattttgtga tttttttgtt gtagttatca
     2461 tatattgttt cagaaactac aatttctttt gttttttcat ttttataagc gttattagct
     2521 atgtagccat atgcattttt atcatttgct tctgtagcta gatattttaa tttagaattt
     2581 ttgtcttcta gctttatttt tttaaatcct tcttttttca tttgcttttc gaatttttgc
     2641 atatcttcat ttttattttg caattgttct agaaaactta tttctttctt ggtcatttgt
     2701 gatacttcga tgtttttgct tttcaatttt tctttttgat tttctagtaa agaacttttt
     2761 tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa ataccagtag gaacaaggaa
     2821 attattgaaa ataattttat aattttcatt tgatacctcc aagataataa gatattttaa
     2881 ttgtataagt aagcgcttta taaaatcaat atttatttta atatatttat aaacatattt
     2941 ttgaaaggag tctattttat gaatgaaaat ttagaaaaat atataaaaag tttgccactt
     3001 ttaggtttgt taattagtat tttgttaatt gttttattct tttttatttt agatgttgat
     3061 gaagatttat tcgtggtttt tttatactgt ttattgcctt tgatagttaa tttgtctatt
     3121 tatggttttt atgtttttgt taaaagaaag taagattatg aataattttg tttttaattt
     3181 gtatgctttg agggggttgg aaaacggtag gtgtatagat tagatttctt gtttttttga
     3241 aacgagtgtg aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt
     3301 tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg
     3361 ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat
     3421 atttatttgg ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata
     3481 tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat
     3541 aaaagctacc ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct
     3601 ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt
     3661 tttcaagaat gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc
     3721 tcaagccgtt tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca
     3781 catgtcgatt tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac
     3841 gaattttaga cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaag
     3901 tagaaccgaa aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact
     3961 tcctaaaact gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt
     4021 gtctccatgt ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag
     4081 aacccttaac taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt
     4141 cgacaagttt tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata
     4201 aagcacctat gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga
     4261 ggtgtattat gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg
     4321 atttattagt aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag
     4381 atatttatgt tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4441 cttttgtatt aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa
     4501 tttatcttgg aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa
     4561 aagaattgaa tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag
     4621 caagttgtgg cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta
     4681 ctaatttatt acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg
     4741 cacaaaaatt agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga
     4801 ttatggctat tatttatata gctttaggtt tatttattat tattgaaaat gacactattc
     4861 aaacaatttt aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata
     4921 cttgtgatgt gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag
     4981 atgataaatc taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga
     5041 aaatcatatt atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat
     5101 tgaaaatgag tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac
     5161 ttgattttta taaagatgga aagatggcat attattttat taaagacgat gaaataagag
     5221 agtttttctc taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat
     5281 aaaaaacaaa gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca
     5341 cagatggtat aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt
     5401 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     5461 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     5521 gccagcatcg aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt
     5581 taatcatttt cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa
     5641 ttaatagtaa atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa
     5701 tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg
     5761 tatagaagtg aatttcctat attccattca tttgctaact tactccatat atcttcacgg
     5821 atattatgat caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac
     5881 ggtaatatat tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct
     5941 tgataattta gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa
     6001 taatcaaaaa tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt
     6061 gcacctaatt tttttgcgat ttctatttgc ttttcttttc ttacgatagc agtgatattt
     6121 tcatatccaa ttttatgtaa aatttgtata gcaacactgc ccacaccacc tgtagcccca
     6181 gacactaaaa tttcaggttg tgatttgata ttcattccat atttttctag ttcaaaaatt
     6241 gataatgctg ccgtaaaacc ggctgtgcca tataccatag actctttaat agacatttct
     6301 tggggaatag gaacaatcca ctctccaggc acttgtgcat attctgaaaa tccacctgta
     6361 tgtgtcacgc caacatcata accagtaact aatacattat cgccttcttt aaacttatca
     6421 ttcgaacttg attcaacaat acctgcaaaa tctataccag gaatcatagg ataatctcta
     6481 attacaccgc ctttatattg taaagctagc atatccttat aatttattga agagtatacc
     6541 acttttacta atacatcacc cttcgataaa tgagattcat caactttttc tactttataa
     6601 ctaacatttg atgcactttt tctcactact accgcattga acatttatta gccttctttc
     6661 acaattgttt tgtagaagta tgtttttgtt gcaaaactat tttcctacaa aacttatcat
     6721 gatatgataa gcgagtcaat actaatgatt taagagaggt tttagttgtg gaattagata
     6781 attgtataaa ttatttgttg agtacttctc agaatagagt ttttaaacat tttaaaagtt
     6841 tattaagtcc ctataatatt actccagcag aatatggtgt tttgaattgc ttgattaata
     6901 gtaatttgaa tacacctaaa gcgattggta atactttaaa tttagaacct tcaacaatat
     6961 ctggaatatt agataagatg tctaaaaagg atctaataac acgtcaaact gataatgaaa
     7021 atagaagaac tgtgctaata aacagtacaa ataaagcaaa agacttatgg ccaacattag
     7081 aaaagaaagc ctatcaactt aataatcatt acttcgctaa tttaactaat gaagaaactg
     7141 tagtgtttaa aaagatatta ctaaagataa ataaaactac gttttaattt ttacgttata
     7201 aaaaagttga agtgcgaatt ataatcgagt aaatataaat gatagcttag cttaattata
     7261 tattaaagcc aactatactt ttattcccga aaaacctact atccaaattt ctaagatact
     7321 ttagcctcta taataaacat attgtaatat aatttatgta ttatttaggt ttaccctaat
     7381 cgaacaataa aaaatacttg taaaatgcta ttgtcacttt gcttgatata tgagaattat
     7441 ttaaccttat aaatgagaaa aaagcaacgc actttaaata agatacgttg ctttttcgat
     7501 tgatgaacac ctataattaa actattcatc tattatttat gattttttgt atatacaata
     7561 tttctagttt gttaaagaga attaagaaaa taaatctcga aaataataaa gggaaaatca
     7621 gtttttgata tcaaaattat acatgtcaac gataatacaa aatataatac aaactataat
     7681 acaaactata agatgttatc agtatttatt atgcatttag aatattaaaa ttccttcatt
     7741 acactcttgg cggtttcact tatcaactta tcatttggct tatcactttt attgtcttta
     7801 ttcgtaaaaa tgactaaaac aataggttca gattggccct taggataaac aaaagcaaca
     7861 tcatttctag aagcatatgt tattgcttga ccacttttat cagcaacctt atagtctttt
     7921 ggaacaccat ctttaattaa agtgtctccg tttttattat taaacattaa atcaagtaag
     7981 aaatttttat tttttttgct taattttcca tttgcgataa gtttatttaa agtcttgccg
     8041 aaagcagcag gcgttgaagt atcttttttg ctctttggtg aatagtaatt taattctatc
     8101 tcatatctaa ctggatttgt tactttatct cctagttctt ttagacgttg tttaactttt
     8161 ttgattccac cgatttcttt tataatttta ttgtttgctg tattatcact atatgtcatt
     8221 gaagcctcaa taagttcttt taaagtgata tcttttccta catatttttc taaaatagga
     8281 gaataagcaa ctatatcatc tttgttaata tgtacttttt tatttaactt attataaggt
     8341 acttgttcta acaaaatagc actatttatc gcttttgaag tcgaagcata ggcaaatctc
     8401 ttatctgaat taaattttac ttccttacca cttttagtat ttaaagcata aacaccaata
     8461 tgagcattat attttttttc taaatcattt aactctttgg catgtgaact gtttgaatta
     8521 catgcactta aaactaaagc aattacaatt aaaaatatta actttttcaa aataaaccct
     8581 ccgatattac agttgtaatt tttataaatc aataatatta caattgtaat attgatgtca
     8641 attgtttatt ataaatattt gaaagaaggt gtcaaaatgg ctaaattact aataatgagc
     8701 gtagtaagct tttgttttat atttctattg ttagtatttt ttaggtacat attaaaacgc
     8761 tattttaatt atagtttaaa ttataaagtt tggtatctaa ctatgcttgc tggattaatt
     8821 ccttttatcc caattaaatt ctcttttata aaatttaata atgtgaataa tcaagcgccc
     8881 acagttgaaa gtaagtcaca cgatttgaac cataacataa ataccaccaa acctattcaa
     8941 gagttcacaa cagatatcca taagtttaat tgggattcaa ttgataatat ctgcacagtt
     9001 atttggatag ttttagttat tattttaagt tttaaatttt tgaaagcctt attatatctt
     9061 aaatatttaa agaaacagtc actttatcta aacgaaaatg aaaaaaataa aatagatacg
     9121 atacttttca accatcaata taaaaaaaat attgtgattc gaaaagcaga ggctattcaa
     9181 tctccaataa ctttttggta tgggaaatat attattttga ttcctagttc atattttaaa
     9241 agtgtaattg ataaaagact aaaatatata atactgcatg aatatgctca tgctaaaaat
     9301 agagatactt tacatttaat tatctttaat atcttctcta ttattatgag ttacaatcca
     9361 ttagtacata ttgtaaaaag aaagataatt catgacaatg aagtagaagc cgatagattt
     9421 gtccttaata atattaacaa aaatgaattt aaaacttatg cggaatctat tatggactcc
     9481 gtattaaaaa ccccattttc caacaaaaat atattaagcc attcatttaa tggtaaaaaa
     9541 tcattactca aaagtagatt aattaatata aaagaagccg atctgaaaaa gcagtcaaaa
     9601 ttaattctaa tttttatttg tatttttact ttttttatca tgataattca aagccagttt
     9661 ttaatggggc aatccttaac tgattataat tataaaaagc ccttacaaag cgattaccaa
     9721 attttagatg aaagtaaaaa ttttggttca aatagtggat ctttcgttat gtacagcatg
     9781 aagaaagaca aatactatat ttataatgaa aaagaaagta gaaaaagata ttctcctgat
     9841 tcaacttaca aaatttattt agcactgttt ggacttgacc gtcatattat aagtgataaa
     9901 aattcacgta tgtcatggaa tcataaacat tatcttttcg agtcttggaa taaggaacaa
     9961 gatttaaata cagcaatgca aaattcagtt aattggtact tcgaacgtat tagtaatcaa
    10021 ataccaaaga actatactgc ggctcaactc aagcaattaa attatggtaa tgaaaatttg
    10081 ggaagttata aaagctattg gatggaagat agtttgaaaa tatctaatct tgaacaagta
    10141 atagttttta aaaatatgat ggaacaaaat aaccatttta gtaaaaaagc aaagaatcaa
    10201 ttatcttctt cattattgat taagaaaaat gaaaagtatg aactgtatgg gaaaacaggt
    10261 acaggtatag taaacgggaa gtataataat gggtggtttg taggttacgt aattacaaat
    10321 catgataagt attattttgc tacacattta tcagatggaa acccgtctgg gaaaaatgct
    10381 gaattaataa gtgaaaaaat attaaaagga atgggtgttt taaatgacca ataagcaagt
    10441 tgaaatatct atggctgaat gggatgttat gaatataata tgggataaaa aatcagtatc
    10501 agctaatgaa attgtagttg aaattcaaaa atataaagaa gttagtgata aaacgattag
    10561 aacattaatc acaagactat ataaaaaaga gattataaaa cgatacaaat cagaaaatat
    10621 ttatttttac tcatcaaata ttaaagaaga cgatattaaa atgaaaactg ctaaaacctt
    10681 tcttaataaa ctgtatggag gggatatgaa aagtttagtg ctgaattttg cgaaaaatga
    10741 agaattaaat aacaaagaaa ttgaagaatt gcgagacatt ttaaatgata ttagtaaaaa
    10801 gtaattagag gtatgtttca aacataatac atatgtaaac catacttgac tcttattaaa
    10861 ttagttttgt taatgacatt taaaatatat tattaaagat gagagtgtcc agaaaataac
    10921 cattttctgt acactcttgt tttttgtcta aataagtaag tattacatag aattatgtgt
    10981 tcaaaaaccc aacaaaaaat ctatgttcac aaaagacctc gtaatcaagt tatggtacac
    11041 taaaggtgta tataggaggt ctgtattttg aaaataggtt atgcaagagt ttcaactgga
    11101 ttacaaaatt tgaatttaca ggaggatcga ttaaatacat atggttgtga aaagatattt
    11161 aatgaccata tgagtggttc aaaaagtaag cgacctggtt tagataaagc aattgaattt
    11221 gcgaggtcag gagatacgat tgttgtttgg agattagata gactaggacg gaacatggag
    11281 gatttaatca cgttagttaa tgaacttaac gaacgaggtg tgagttttca tagtttagaa
    11341 gaaaatataa cgatggataa atcaagttct acaggacaat tattatttca tttattcgca
    11401 gcatttgcag agtttgaacg taatttaatt ttagagcgat catcagccgg tcgaattgca
    11461 gcacgtgcta gaggccgata tggaggtaga cctgaaaaat taaataaaca agatttaaac
    11521 ttacttaaga cactttatga taatggtacg ccaattaaaa caattgcaga gcagtggcaa
    11581 gtttcacgta caactattta tcgttatctc aataaattag aggcaaaaga gaataaaaac
    11641 aagtagagca actaatctag cttactataa tgaatctact aaataatttt atatatcatt
    11701 aacatacaaa gactttgatt caatgtcact cgatgtaaaa gagacgttct gacagcgtct
    11761 aaaatctcat aatattttcc tgttatgaga ttttaataat aacacaagaa aaaagcgtac
    11821 aaattcgtac gcttttttaa tataatacct gtttcactaa tgaacgtttt aagtatcttc
    11881 atcattaact gaaactacag taataatact cgtcaacaat attagtatag ttaaaataga
    11941 aagacttagg actggcataa ccgaactaaa attatatttg aaatataaaa gtgctaatga
    12001 agagagaaat gtaaaaataa taaataccaa agaccatttt tctaatttat tcattggctt
    12061 cacctctttg aacttttata taatcatagg agatattttt actacgattt ataaaaaata
    12121 agaagataat cattattaaa gaaacgatta atataatgtt gaatcctata gtatcaccta
    12181 attcgtttac acctttgcct aatatcggag atacaaagct ttgtattaat aatgaaagag
    12241 atgcccatat agtaaatgag gttctgttgc aaagttgaat ttatagtata attttaacaa
    12301 aaaggagtct tctgtatgaa ctatttcaga tataaacaat ttaacaagga tgttatcact
    12361 gtagctgttg gctactatct aagatatgca ttgagttatc gtgatatatc tgaaatatta
    12421 agggaacgtg gtgtaaacgt tcatcattca acggtctacc gttgggttca agaatatgcc
    12481 ccaattttat atcaaatttg gaagaaaaag cataaaaaag cttattacaa atggcgtatt
    12541 gatgagacgt acatcaaaat aaaaggaaaa tggagctatt tatatcgtgc cattgatgca
    12601 gagggacata cattagatat ttggttgcgt aagcaacgag ataatcattc agcatatgcg
    12661 tttatcaaac gtctcattaa acaatttggt aaacctcaaa aggtaattac agatcaggca
    12721 ccttcaacga aggtagcaat ggttaaagta attaaagctt ttaaacttaa acctgactgc
    12781 cattgtacat cgaaatatct gaataacctc attgagcaag atcaccgtca tattaaagta
    12841 agaaagacaa ggtatcaaag tatcaataca gcaaagaata ctttaaaagg tattgagtgt
    12901 atttacgctc tatataaaaa gaaccgcagg tctcttcaga tctacggatt ttcgccatgc
    12961 cacgaaatta gcatcatgct agcaagttaa gcgaacactg acatgataaa ttagtggtta
    13021 gctatatttt tttactttgc aacagaacca gcatttgttt taatatttgt tccaaagagc
    13081 catcatggct ttgacagagc tcttcttcta tgcaaatgct tttaatccga tccacacgaa
    13141 aattcctata ttcatttctt agcctgcaaa accgattaag taccagttct gttcataaaa
    13201 ccccagtgat ataggctcta tcattctgct ttccggttct tgccctcctg atgcaggata
    13261 ttgaattgat attacccttt tattgcagat tgcagtctga attgctgcaa taacgttatc
    13321 cgccaatgta tttttctgtc cagatgtgct gtacacgtta atactgttct ccaactcctg
    13381 tgcatagttt ttttcaccat gcttcaaaat agatttgatt ttatacatag ctgaatcaaa
    13441 atcctttata aatgattcat ctccatggca atttaaaaat ttccctgctg taatcaatgc
    13501 acccacttcc gccgctgtaa acattaccgg cagaagtagg aagccctcta caagaaaata
    13561 tccttttccg gcctcagatc caattggtat tccggcttct tcaagtgtcc ggatatctct
    13621 gtaaactgtc cttaagctta tattaaatcg ctgtgcaatt tctttggcag gaattatttt
    13681 tttgattgca gctgaataag aatagaggtt actctgttaa tcctgttcaa attttattcc
    13741 tcctctgtga cttccataaa aagtatatcc tatgcgttct taagctagct gctgttagtg
    13801 cttctcattg caccctggtt ataaaagcca tactcacaaa cctcttcacc aaaactcttt
    13861 acatctctaa tatagaactc tatctagcga acttttagaa aagatataaa acatcagagt
    13921 atggacagtt gcggatgtac ttcagaaaag attagatgtc taaaaagctt gtagttaaag
    13981 ctttttagac atctaaatct aggtactaaa acaattcatc cagtaaaata taatatttta
    14041 ttttctccca atcaggcttg atccccagta agtcaaaaaa tagctcgaca tactgttctt
    14101 ccccgatatc ctccctgatc gaccggacgc agaaggcaat gtcataccac ttgtccgccc
    14161 tgccgcttct cccaagatca ataaagccac ttactttgcc atctttcaca aagatgttgc
    14221 tgtctcccag gtcgccgtgg gaaaagacaa gttcctcttc gggcttttcc gtctttaaaa
    14281 aatcatacag ctcgcgcgga tctttaaatg gagtgtcttc ttcccagttt tcgcaatcca
    14341 catcggccag atcgttattc agtaagtaat ccaattcggc taagcggctg tctaagctat
    14401 tcgtataggg acaatccgat atgtcgatgg agtgaaagag cctgatgcac tccgcataca
    14461 gctcgataat cttttcaggg ctttgttcat cttcatactc ttccgagcaa aggacgccat
    14521 cggcctcact catgagcaga ttgctccagc catcatgccg ttcaaagtgc aggacctttg
    14581 gaacaggcag ctttccttcc agccatagca tcatgtcctt ttcccgttcc acatcatagg
    14641 tggtcccttt ataccggctg tccgtcattt ttaaatatag gttttcattt tctcccacca
    14701 gcttatatac cttagcagga gacattcctt ccgtatcttt tacgcagcgg tatttttcga
    14761 tcagtttttt caattccggt gatattctca ttttagccat ttattatttc cttcctcttt
    14821 tctacagtat ttaaagatac cccaagaagc taattataac aagacgaact ccaattcact
    14881 gttccttgca ttctaaaacc ttaaatacca gaaaacagct ttttcaaagt tggcgtataa
    14941 catagtatcg acggagccga ttttgaaacc acaattatga tagaatttac aagctataag
    15001 gttattgtcc tgggtttcaa gcattagtcc atgcaagttt ttatgctttg cccattctat
    15061 agatatattg ataagcgcgc tgcctatgcc ttgccccctg aaatccttac atacggcgat
    15121 atcttctata taagcgtacc ggttccaatt ttttcgcagt ttaacttttc cgacgcattt
    15181 atcgtcttgg tagtaaagat atattatctt atcagtattg tcaatatatt caaggcaatc
    15241 tgcctcctca tcctcttcat cctcttcgtc ttggtagctt tttaaatatg gcgcttcata
    15301 gagtaattct gtaaaggtcc aattctcgtt ttcatacctc ggtataatct tacctatcac
    15361 ctcaaatggt tcgctgggtt tatcgatatc tttcaggtgc cctgctttca tttctgtaat
    15421 cactgttccc gcctctcttc tatatcagcg gcatatgtgc tatccaggca gccggtttta
    15481 ccagtgtatt ttttatacat gtccctggta tattttgtta tattcctatc atactccgga
    15541 taggcataat gaagccttta cgccacctca ccggataccg ccctgaacaa ttgatggcat
    15601 agaaataatg cttcccatat gttttcatag gaatccatcc ggtaggtgga caaaagtttc
    15661 tcccacaaat cctcggatat atacctttca ataaacttat agttcttgcc tacacttcat
    15721 ttaaagcctg tttcgatgcc gaccttccat gatatcattc tcagcagctc atggcgaaca
    15781 atctgattaa aatgatcaat agcaaataaa atttccttac ggcacaatcc tttaataaca
    15841 taaggtgtta cattccaaaa ttcattgcag caatcatcat actcccttgc gcttggcttt
    15901 cttacatgat aatctatatc agtcggaact atgtcccttt taattctaca atctttatca
    15961 attagaacct ttattaattt atcgcccttt aggtaattat ctaactcttc caagggcaat
    16021 aaggtaagat caattttatt gtaatcatca aatagctata atagatttag aggtaaagaa
    16081 attaaataca ttgaagagca gaaagatttt acaaaagagt attttaataa aaatgatggt
    16141 tctgttgcaa agtaaaaaat atagctaatc actaatatat catgtcagtg ttcgtttaac
    16201 ttgctagcat gatgctaatt tcgtggcatg gcgaaaatcc gtagatctga agagacctgc
    16261 ggttcttttt atatagagcg taaatacact caataccttt taaagtattc tttgctgtat
    16321 tgatactttg ataccttgtc tttcttactt taatatgacg gtgatcttgc tcaatgaggt
    16381 tattcagata tttcgatgta caatggcagt caggtttaag tttaaaagct ttaattactt
    16441 taaccattgc taccttcgtt gaaggtgcct gatctgtaat taccttttga ggtttaccaa
    16501 attgtttaat gagacgtttg ataaacgcat atgctgaatg attatctcgt tgcttacgca
    16561 accaaatatc taatgtatgt ccctctgtat caatggcacg atataaatag ctccattttc
    16621 cttttatttt gatatacgtc tcatcaatac gccatttgta ataagctttt ttatgctttt
    16681 tcttccaaat ttgatataaa attggggcat attcttgaac ccaacggtag atcgttgaat
    16741 gatgaacgtt tacaccacgt tctcttaata tttcagatat atcacgatag ctcaatgcat
    16801 atcttagata gtagccaacg gctacagtga taacatcctt gttaaattgt ttatatctga
    16861 aatagttcat acagaagact cctttttgtt aaaattatat tataaattca actttgcaac
    16921 agaacctcct aactgtatta ccaccttaaa agtagttgca gacgcacttc ctaaatcgtc
    16981 agcagtgttt aaccacatat catcaacaat aatcatatga cctgttgatg atactggagc
    17041 aaattctgtc aacccttcaa ctacacctaa aataaatgct ttaatctgct ctataaaacc
    17101 catttttctc ctccttttaa cttatatcag tttttttaaa gtatgagaat aatataatta
    17161 cactgaatat agatgtaaca attatgataa ttaaagataa tagaaatgga taagtattag
    17221 gtaatgttcc tctagatatg tctccaactg cagcccaagg aaataatcct ctatgttcag
    17281 aattagcagt cattaaattt atcaaagtaa ttattatggt taaaacaatt gtgggaacat
    17341 aatttttaaa atatatcgac aaaataatta ttggtggaga taatatccat aataacactc
    17401 cgccaataac aaatgtaaag aatgaatcaa ttattaaact ctggcttaac ccttgaaaat
    17461 gcaatagcat acctagcatt aaagttagca accatgcaat aacagatagt gtttgaatcc
    17521 acaagaataa taatattatt ttacttacta aaaaactttc tctagatata ggtataatta
    17581 ataagttttt taaagtatct tctatatatt ctcttccaaa caaataggct attataaccc
    17641 catatagagg aggtccaata attagcatat gatataaact gacttcttca aataactgtt
    17701 taaatacaat attaggagtc ggtactttcg tccgcatact aataaaagaa gctacaacca
    17761 ccataaaagg tgctacgcat gtacctaaaa tacttattag aaacatatat gatcttttta
    17821 acttaataaa ttctgtacgg agtagattat ccaattgtgc cacctcctac taagtcttcg
    17881 aaataagttt ctagattatc ttctatcact ctcatctgga aaacatcaat attgtttaat
    17941 actaataatc tattaatttc ttgttgtcta tcaatatgtg aataaatttt aaattcgcca
    18001 ttttctttaa ttttatagtc ataaattccg aagttagttt ccaacaaaca tgcaactttt
    18061 tcttcatctg atactgatat acttataaat tgtctgttct ttttttttaa atcttcatac
    18121 ataatttctt ctaacaaaac tccgttatga ataataccca ccttgtctac taactgctct
    18181 atttctgaca atatatgact tgaaattaaa atggttatat ttctagattg agccagatcc
    18241 ttaatcaact ttctaatttc ttttatgcca ataggatcta atccattcgt cggctcatca
    18301 agtatcaata attcgggatt gtgcaataaa gctctcgcaa tccctaaacg ttgcttcata
    18361 cctaaagaat aatttttaaa caattttact ttttcagaag ctagtcctac tatttctaac
    18421 acttcttcaa ttgcattttc tttttgtata cctaatattt tagcatttat agttaagttc
    18481 tctttagctg tcaaattact ataaaaacct ggcgtttcaa ccatagcacc aatatttttt
    18541 aaaatttcag ttttattact ttcgaactct ttttcaaata ttttaatatt acctttcgta
    18601 ggtttaatta agcctaaaag cattcttata gtagttgttt tgcctgcacc atttcttcct
    18661 aaaaaaccat aaatttgtcc actttcaaca gttatactca aattattaac tgctatctga
    18721 cttccatatt gctttgttaa gttatttatt tcaattatat tattcaaatt tttcacctct
    18781 ggcacctttc ttagtttgtt gttaccttta tcttacgcgc gattagaaaa ggctgccttt
    18841 atctattctt acaaaaacag ccgctaatct tacaaaaatg aaagattgga gttatttaaa
    18901 ttgaatggtg aatattgaac catcgtttaa tgtagatgta gcacttactt tatggcctaa
    18961 gcgctttgag attgtgctga caatatataa accaataccg cttgatttct cacttattct
    19021 accgttatag cccgagaaac ctttatcaaa gattttcggt aaatcactcg cattaatgcc
    19081 gataccgtta tctcggattg ataatttctt tgtattttcg tcaaacgtaa tccacacatc
    19141 tttgccacgt gcatatttta atgcattgtt taatatttgc tcaatcataa ttgatgccca
    19201 tttggcatct gttaatataa ccgcttcact tttctcataa tgcaactttg tttgatgatg
    19261 aataaactgt atcgcataac gtttaatcag tggtcgaatt aattcatcta cactcacttc
    19321 cataaagacc atgtatgtct tttggttcat gagtttcaaa tagttcagtg caagattcgt
    19381 gtaattatca atttgtaaga cttcattacg cacgttagaa atcacgtgtt catcaggatc
    19441 ttcaagcagt aactttgatg ctgtaatcgg tgtcttgatt tgatgcaccc acattaaaaa
    19501 atatgactct aactcacttt ggtagttaat aaagtcatta cgaagtttat ggttttcgat
    19561 tcttaaatct tcgttctgtt cctgtagtgt ttattctttt ttaaagttca tgtaatggat
    19621 accccagtaa atcattgaaa caaacaatac aatacctaga ccaatcatat atgcttgcat
    19681 cggcacatta tacatgaata atataaagta gaataaagca caagtaagga tgacaatata
    19741 aatttcacgt tggattgatt tcaagaaatt catacgtcac ctacacgata tccgacattt
    19801 ttcttcgttt cgataaaatc tgtaagtcct agtttttgta gctttttgcg taaacgtgta
    19861 atgttgacag caagcgtatt gtcatcaatg aagtgttctg attcccagca tttttcgatt
    19921 aacgcattac gactgacgaa tttgcccttg ttctggaata agctatgcat gatttgcaat
    19981 tcagtgtgtg tcaggtctat ggtttcttca ttaaatttaa gctttgctgc atcaagtagt
    20041 aactcgcaat catctactgt taaattatta acttgagtgg tgaaatcata cgtgcggcgt
    20101 aatagtgctt gaatcttagt aattgtaaca gtcatattaa atggctggtt ctgttgcaaa
    20161 gtaaaaaata tagctaatca ctaatatatc atgtcagtgt tcgtttaact tgctagcatg
    20221 atgctaattt cgtggcatgg ggaaaatccg tagatctgaa gagacctacg gttcttttta
    20281 tatagagcgt aaatacattc aatacctttt aaagtattct ttgccgtatt gatactttga
    20341 tatcttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt attcagatat
    20401 ttcgatgtac aatgacagtc aggtttaagt ttaaaagctt taattatttt agccattgct
    20461 gccttcgttg aaggtgcctg atctgtaact accttttgag gcttaccaaa ttgtttaatg
    20521 agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct
    20581 aatgtatgtc cctctgtatc aatggcacga tataaatagc tccattttcc ttttattttg
    20641 atatacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt cttccaaatt
    20701 tgatataaaa ttggggcata ttcttgaacc caacggtaga tcgttgaatg atgaacgttt
    20761 acaccacgtt ctcttaatat ttcagatata tcacgatagc tcaatgcata tcttagatag
    20821 tagccaacgg ctacagtgat aacatccttg ttaaattgtt tatatctgaa atagttcata
    20881 cagaagactc ctttttgtta aaattatatt ataaattcaa ctttgcaaca gaaccgtatt
    20941 ttatgagtac actctaaatt aaggagatgt ataatcaatc taaaattgta tttttatact
    21001 tttgttatat aatctttcta cttagagata tattgtaaaa aaaccaacaa aatgttatat
    21061 taacattact attttatcga tgaaggagga ttaaaatgac agcttctatg agactcaaat
    21121 aaaccttttt gaatacaaaa ctaaattaat tcaaaaaggc ttgtccgcaa tacacactca
    21181 taggatgact tatgtcattt tttatccttc gataggaata ataaacgctt tcaaatacta
    21241 aaacatcata ataaattttt aagtgtttga aagtgtaatg tgaatgagac gggagtagcc
    21301 tgtctcattt ttttgcgtac acgtccttta aatatacaag gagtgtataa atatggaaca
    21361 atatacaatt aaatttaacc aaatcaatca taaattgaca gatttacgat cacttaacat
    21421 cggtcatctt tacgcttacc aatttgaaaa aatagcactt attgggggta atggtactgg
    21481 caaaaccaca ttactaaata tgattgctca aaaaacaaaa ccagaatctg gaacagttga
    21541 aacggttggc gaaattcaat attttgaaca gcttaacatg gatgtggaaa atgattttaa
    21601 cacgttagac ggtagtttaa tgagtgaact ccatatacct atgcatacaa ccgacagtat
    21661 gagtggtggt gaaaaagcaa aatataaatt agctaatgtc atatcaaatt atagtccgat
    21721 attactttta gatgaaccta caaatcactt ggataaaatt ggtaaagatt atctgaaaaa
    21781 tattttaaaa tattactatg gtactttaat tatagtaagt catgatagag cacttataga
    21841 ccaaattgct gacacaattt gggatataca agaagatggc acaataagag tgtttaaagg
    21901 taattacaca cagtatcaaa atcaatatga acaagaacag ttagaacaac aacgtcaata
    21961 tgaacagtat ataagtgaaa aacaaagatt gtcccaagcc agtaaagcta aacgaaatca
    22021 agcgcaacaa atggcacaag catcatcaaa acaaaaaaac aaaagtatag caccagatcg
    22081 tttaagtgca tcaaaacaaa aaggcacggt tgagaaggct gctcaaaaac aagctaagca
    22141 tattgaaaaa agaatggaac atttggaaga agttgaaaaa ccacaaagtt atcatgaatt
    22201 caatttccca caaaataaaa tttatgatat ccataataat tatccaatca ttgcacaaaa
    22261 tctaacattg gttaaaggaa gtcaaaaact gctaacacaa gtacgattcc aaataccata
    22321 tggcaaaaat atagcgctcg taggtgcaaa tggtgtaggt aagacaactt tacttgaagc
    22381 tatttaccac caaatagagg gaattgattg ttctcctaaa gtgcaaatgg catactatcg
    22441 tcaacttgct tatgaagaca tgcgtgacgt ttcattattg caatatttaa tggatgaaac
    22501 ggattcatca gaatcattca gtagagctat tttaaataac ttgggtttaa atgaagcact
    22561 tgatcgttct tgtaatgttt tgagtggtgg ggaaagaacg aaattatcgt tagcagtatt
    22621 attttcaacg aaagcgaata tgttaatttt ggatgaacca actaattttt tagatattaa
    22681 aacattagaa gcattagaaa tgtttatgaa taaatatcct ggaatcattt tgtttacatc
    22741 acatgataca aggtttgtta aacatgtatc agataaaaaa tgggaattaa caggacaatc
    22801 tcttcatgat ataacttaaa aactatacac taatttatat tgaatattag gttcatttat
    22861 atcaatataa aaaatacgtt cacaagaaaa atataataga aataaggatc caataaaatg
    22921 actcgacata atgaaattat taaatgtgca gaaaaatatc aattacacat ccaacctcaa
    22981 acaatctcat tgaatgaatc gggacttgat tttcaagttg catttggaaa agataaacat
    23041 ggagtagaat gggttttgag actaccaaga agacctgacg tttataaacg aacaaaaccc
    23101 gaaaaacaaa cggtagactt cttacagaag aatgtttcat ttgaaatacc gaagtggaaa
    23161 gtacatgcaa aagaccttat tgcttaccca aaacttacag gtaaacccgc agccacaata
    23221 gatccagaaa tacaaaatta tgtatgggaa attgaacaca aaccattacc agaaaacttt
    23281 attaacacat tagctgaaac actcgtagat ttacacaaca taccagaaga aaacattaac
    23341 gttcagcata taaatatcaa aaccatacaa gaaataaaaa atgactttca aagaagaatg
    23401 aataaagtta aagaaactta tggcgtatca gatgaattat ggaacagatg gaaacaatgg
    23461 ttagaaaacg acgaactatg gcctcgacat gcgaccatga tacatgggta cttacatcca
    23521 ggacatataa tggtagataa ccaagcaaac gtcacaggtc tcatagactg gactgaagca
    23581 acccactccg acccatcaat ggactttata ggacaccatc gtgtattcga cgacgaagga
    23641 ttagagcaac ttataacagc atacggtaaa gctggaggtg aaatatggcc acgaatgaaa
    23701 gagcatataa tagaactcaa tgcagtattc ccaatgttta tcgctgagtt tgctatggaa
    23761 tcaggagaat cggcgtatga aacgatggca ttgaaagagt taggtatgaa agagtagaac
    23821 ttatattaaa agaggcccat tttaaagacg aaggcaatcc tgatgaaatt ttaaaactgc
    23881 gtttaattag tgatggtctt tggttttcta taatgtatta aatatctgga catggaacaa
    23941 atgcaacaaa tggaaagaat cgttttcgaa atttctaact ccttaaatca ggaggataaa
    24001 taaacggtca ttttcattga aagcacttat ataaatttca tcaattttaa tacctaccgt
    24061 aaatacattt cataagtatt aaacagatga ttaaaatttt tagttaattt aaatatttat
    24121 gatagagatg accttcaaat gaacggttct gttacaaaga aaaaatctat atttattttt
    24181 agtaagtttt aattatagat atgtacactt tgagtacacc ctaaccatac aaaaagaatt
    24241 gttgaaatta taacaattaa aacgtatgat tagggtgtat atttattatg gagtgaagat
    24301 gaatgattat aggttatgcg agagtatcat cgatagatca aaatttagaa agacaattgg
    24361 ataatttaaa gacgtttggt gtggagaaaa tctttacaga gaaacagtcg ggaaagtcag
    24421 tggaaaatag acctgtattt caagaagcac tcaattttgt cagaatggga gatcgattcg
    24481 ttgtggaatc tattgatcgt ttaggacgta actatgatga aattattgaa actgtgaatt
    24541 atttaaaaga aaaagacgtt cagttaatga ttaccagctt acctatgatg aatgaagtaa
    24601 ttggcaatcc attactggat aagtttatga aagatttaat cattcaaata ttagcaatgg
    24661 tttcagaaca agagagaaat gaaagtaaac gtcgacaagc gcaagggatt caagttgcga
    24721 aggaaaaagg cgtatataaa gggcgccctt tactttattc accaaatgct aaagacccac
    24781 agaaacgtgt tatttatcat cgcgtggtgg aaatgttaga agaaggcaaa gcgattagta
    24841 agattgcgaa agaagttaat atcacaagac aaacagttta tagaattaaa catgataagg
    24901 gattatcttg ataaattgat tgtcaatgca aatgagcgtc tctcacagtg tctcaaattc
    24961 cataacatat tattgaattg agattttaat aattatacaa gaaaaaagag tacgagttcg
    25021 cagctttcta tatagtaatt gttttactaa taaggtgttt taaaatatat tataatgtaa
    25081 aaagtatttg acatttgtat caaaaatatt tacactcata aatgtcaaat actttttaca
    25141 tttatgaggt gttataatga atttaattcc ttttattatt attttaattt tttcttgttt
    25201 atggacggct ataactaaca aatatttacc ttcagaaaca ttagataaaa aaggacaaca
    25261 agatcgatac gatgaaagac aacgtaaaat gtttattgaa atactggcta aaagttttat
    25321 ttggattgta tattgtatgt tatttacact agtgcttaaa tttacaggtt tgtcaccaag
    25381 tattgaagga tcttggtttt ctcaatatcc agaaattttc tttataattg tagcactatt
    25441 tcttatgctg tttaattact atactacaaa taaaaaatat acatctaaag gttaaattaa
    25501 tgaaaaatag aattagagaa tatagaaaac aaaaaggaat ttctcaagaa actttaagta
    25561 aagaattaaa agtgtctagg caaactatta atgcaataga aaacaataaa tatgatccta
    25621 cattgacatt agcatttaag ttggcaagat tgtttgatac aactgtggat gaattatttt
    25681 cttaaccatt catttatcac aaaaagagag tgcgaattcg cactctcttt ttgtgtagta
    25741 gtactattaa attttgtctc aataacgaac gtttataacg caatcatgat gagagtatta
    25801 atacagttaa ttatttgaaa tactttagtt tacataatcg atgattacca gaagttctca
    25861 ctatataaaa gacactaaaa ttttataact tttagtgcct aatcaattat tttagctacc
    25921 aaacaaacga ctccaaaacc cctttttagg ttccgtttct tcactctttt cttctatatc
    25981 actatcattg tcatttagat tagctggaac gtcttctttt tttgcttctt caccttgtgt
    26041 actttcgtcg ctttgacttc cagatatatc cttatattga atctctgttt ctttagtttc
    26101 ttcctgatct ctgttaatat ttacaggatt agtagtatat gttttttctt gtgcatcaac
    26161 gttttgtcta gtgttagtag atgtatcaaa gggataatta aggtgttttt ctttttctaa
    26221 ttgattttct aatttttgaa tctttttatt actctctaat gccagaactt gctgattttc
    26281 aagcaatttt gatctttctt gcaactcttt tctgtaaaat tcaattgttg tttcatgacg
    26341 actttcttgt ttttcaattt gattatttaa agtatcaatc tgatttttaa ggatttctac
    26401 tatttgagca tcgcttttcg attcaaaatt aatattatcc gacccttttt tttgtttgtc
    26461 ttcagtagta ctttcaaaac catatttctt tttattttca tttactcttt gaatgatttt
    26521 ttctatatcg gtatcttctt taataaacga agtgttttcc tgttttattg tctctatatt
    26581 caatcgctta atattattaa aaatcgtttg cttactaacc cctaattctt cactcaactt
    26641 tttcacactt ttcatatcat caacccttta taaaatgttt ataaaccctt gataaaatat
    26701 tataagctta taatgcttaa taataaagtg attaataaat aaaaataaac atccatcaac
    26761 ctttttatca agggtttatg aaaggtttat gatatttatc aagggtttat aaacccttga
    26821 taaagctata ttttcccttt tataagttta tttaaagtgc tataataaac ttaatataac
    26881 aaaaacccca actactggta atagtcgggg tttggtaata aaacgtttag aaactgttta
    26941 tttatataat tttcgatact tgtattatat aatgaataat atcttagtgc aagcacctaa
    27001 atcattaaat aaatgtaaag ctaaataaaa acgttttatt acctcttacc aaactaaaat
    27061 atggaaagag gttttttgtc
//
