LOCUS       NZ_CP116530            24566 bp    DNA     circular CON 01-MAR-2024
DEFINITION  Enterococcus faecium strain K188-5 plasmid pK188-5-B, complete
            sequence.
ACCESSION   NZ_CP116530
VERSION     NZ_CP116530.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23424531
            Assembly: GCF_028335485.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24566)
  AUTHORS   Biggel,M.
  TITLE     Oxazolidinone resistance genes in florfenicol resistant enterococci
            from beef cattle and veal calves at slaughter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24566)
  AUTHORS   Biggel,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JAN-2023) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x, 50x
            Sequencing Technology :: Illumina MiniSeq, Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/01/2024 01:52:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,802
            CDSs (total)                      :: 2,712
            Genes (coding)                    :: 2,623
            CDSs (with protein)               :: 2,623
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 35 of 89
            Pseudo Genes (incomplete)         :: 47 of 89
            Pseudo Genes (internal stop)      :: 24 of 89
            Pseudo Genes (multiple problems)  :: 14 of 89
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116530.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="K188-5"
                     /isolation_source="fecal sample"
                     /host="Bos taurus"
                     /db_xref="taxon:1352"
                     /plasmid="pK188-5-B"
                     /collection_date="2021"
                     /collected_by="ILS, University of Zurich"
     gene            join(24246..24566,1..252)
                     /locus_tag="PML77_RS13730"
                     /old_locus_tag="PML77_13730"
     CDS             join(24246..24566,1..252)
                     /locus_tag="PML77_RS13730"
                     /old_locus_tag="PML77_13730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(685..1644)
                     /locus_tag="PML77_RS13735"
                     /old_locus_tag="PML77_13735"
     CDS             complement(685..1644)
                     /locus_tag="PML77_RS13735"
                     /old_locus_tag="PML77_13735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="WP_000222577.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINFL
                     KEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPISCS
                     VRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEFGHI
                     EGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFKSITF
                     DCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQVDQAF
                     ISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
                     /name="IS30-like element IS1252 family transposase"
     gene            complement(1772..2452)
                     /locus_tag="PML77_RS13740"
                     /old_locus_tag="PML77_13740"
     CDS             complement(1772..2452)
                     /locus_tag="PML77_RS13740"
                     /old_locus_tag="PML77_13740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(2506..4134)
                     /gene="poxtA"
                     /locus_tag="PML77_RS13745"
                     /old_locus_tag="PML77_13745"
     ARG             complement(2510..4134)
                     /name="poxtA"
                     /gene="poxtA"
                     /gene_name="ABC-F type ribosomal protection protein PoxtA"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/OXAZOLIDINONE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(4891..5571)
                     /locus_tag="PML77_RS13750"
                     /old_locus_tag="PML77_13750"
     CDS             complement(4891..5571)
                     /locus_tag="PML77_RS13750"
                     /old_locus_tag="PML77_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            5650..6882
                     /locus_tag="PML77_RS13755"
                     /old_locus_tag="PML77_13755"
     CDS             5650..6882
                     /locus_tag="PML77_RS13755"
                     /old_locus_tag="PML77_13755"
                     /inference="COORDINATES: protein motif:HMM:NF037897.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_214308138.1"
                     /translation="MGFNSLPLNDNHIIKENTTTEKRSKIDNLYHGSKEDFTEFKIPRF
                     HKNGGTLGFGTYLTDSLQRAKSYADNDGYLYTIELNDELQNSTPLNASKVTLTTNQVAK
                     IIEKIAQKQIDEEEYPYILSDWEEPTSETAMDAGNKKIAYNIAEKIIDDTDDLSIINGI
                     NNQLGGNDSGAETLIPVLNEMGIHYAELDVEYYDNSKEYVVFNPKDIKIVNQKLTKPEQ
                     SKKFVSDVDIKSLEEKAIKTIAKSELIVKANNPVEAMQKLYNNDLKSAIKASFILYDLP
                     EDKIDSSKKNVTWEDLVNIEKSYNVFSYYQNNLYGSELVEPDLNNPYQENTKILDNKAT
                     QKQPALSDQYKALHDKLKEPGANKQQIQEQLNKVKIEISQKTQQQLKDFAKANPDLKQP
                     RVKKEQQALQR"
                     /name="hypothetical protein"
     gene            complement(7212..8621)
                     /gene="fexB"
                     /locus_tag="PML77_RS13760"
                     /old_locus_tag="PML77_13760"
     ARG             complement(7216..8621)
                     /name="fexB"
                     /gene="fexB"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FexB"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9025..>9378)
                     /locus_tag="PML77_RS13765"
                     /old_locus_tag="PML77_13765"
                     /pseudo=""
     CDS             complement(9025..>9378)
                     /locus_tag="PML77_RS13765"
                     /old_locus_tag="PML77_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169163.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(9732..9989)
                     /locus_tag="PML77_RS13770"
                     /old_locus_tag="PML77_13770"
     CDS             complement(9732..9989)
                     /locus_tag="PML77_RS13770"
                     /old_locus_tag="PML77_13770"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_013330744.1"
                     /translation="MTKYSESFKEMIVDLANNGTKAKDLSSEYGISEAAIYKWKKLYTK
                     DSKTGVNEKQMQTLRKEIKQLKLENEILRKAAAIFAQDPL"
                     /name="transposase"
     gene            complement(10126..10656)
                     /locus_tag="PML77_RS13775"
                     /old_locus_tag="PML77_13775"
     CDS             complement(10126..10656)
                     /locus_tag="PML77_RS13775"
                     /old_locus_tag="PML77_13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002510381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_125276271.1"
                     /translation="MDTVRDFILYLKLCNRTVTRYILKQKTLGLFFLALTPVIDLILLI
                     TTGIDLMNGATAATPHAIAAVYISVSLVFGKSMINWADDRFGYYVMKQGPKPYKPVGLA
                     YSKNYAKSWLKHLLSYIIGTGILHLIIFLINDKSRTEAMDNVIHVWTIVIIIDLIICIS
                     YFVWPPKNTESKL"
                     /name="hypothetical protein"
     gene            complement(10660..11340)
                     /locus_tag="PML77_RS13780"
                     /old_locus_tag="PML77_13780"
     CDS             complement(10660..11340)
                     /locus_tag="PML77_RS13780"
                     /old_locus_tag="PML77_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            11402..11803
                     /locus_tag="PML77_RS13785"
                     /old_locus_tag="PML77_13785"
     CDS             11402..11803
                     /locus_tag="PML77_RS13785"
                     /old_locus_tag="PML77_13785"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_231411522.1"
                     /translation="MQQNHISYLFQNYALLENQTVQYNFELAKKFNSNISNDHIYNLLT
                     DFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEPTGNLDKENSTFIMNFLK
                     NLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
                     /name="ATP-binding cassette domain-containing protein"
     gene            11917..12054
                     /locus_tag="PML77_RS13790"
                     /old_locus_tag="PML77_13790"
     CDS             11917..12054
                     /locus_tag="PML77_RS13790"
                     /old_locus_tag="PML77_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303562.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESYC
                     "
                     /name="hypothetical protein"
     gene            12496..12876
                     /gene="mobC"
                     /locus_tag="PML77_RS13795"
                     /old_locus_tag="PML77_13795"
     CDS             12496..12876
                     /gene="mobC"
                     /locus_tag="PML77_RS13795"
                     /old_locus_tag="PML77_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_002317440.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEALQ
                     MSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASGDA
                     QRLSENLKIMQKELQKIWQQLR"
                     /name="mobC"
     gene            12858..13772
                     /locus_tag="PML77_RS13800"
                     /old_locus_tag="PML77_13800"
     CDS             12858..13772
                     /locus_tag="PML77_RS13800"
                     /old_locus_tag="PML77_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_002340563.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQTAIYTHTDKDHIHNHI
                     VINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKLKEK
                     NEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKKKVRS
                     NRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTPEQPEI
                     RPARRNHEQHVERGTDHQQELSL"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            13732..14010
                     /locus_tag="PML77_RS14055"
     CDS             13732..14010
                     /locus_tag="PML77_RS14055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002348700.1"
                     /translation="MKEEQTTNKNYRSKTLKDIENEIKKQRAFLVPYTQERIQTTIDLQ
                     VKKLHQELLDQRNKEQKKVLIQRSLDFLAPLCCLVLTLFAFWLVWGG"
                     /name="hypothetical protein"
     gene            14012..14701
                     /locus_tag="PML77_RS13805"
                     /old_locus_tag="PML77_13805"
     CDS             14012..14701
                     /locus_tag="PML77_RS13805"
                     /old_locus_tag="PML77_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002298772.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIEEA
                     CSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKSVKEW
                     LDQQQQN"
                     /name="hypothetical protein"
     gene            complement(14822..14908)
                     /locus_tag="PML77_RS13810"
                     /old_locus_tag="PML77_13810"
     CDS             complement(14822..14908)
                     /locus_tag="PML77_RS13810"
                     /old_locus_tag="PML77_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018113589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_110300541.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            15553..16290
                     /locus_tag="PML77_RS13815"
                     /old_locus_tag="PML77_13815"
     CDS             15553..16290
                     /locus_tag="PML77_RS13815"
                     /old_locus_tag="PML77_13815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_002305239.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEIF
                     TFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDKVN
                     ETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKGHWF
                     VKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAYKGNK
                     IGSLQIYFEENIPSITLDNWLEK"
                     /name="replication initiation protein"
     gene            16318..16857
                     /locus_tag="PML77_RS13820"
                     /old_locus_tag="PML77_13820"
     CDS             16318..16857
                     /locus_tag="PML77_RS13820"
                     /old_locus_tag="PML77_13820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002289340.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKVV
                     LRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLREQL
                     SLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEETESI
                     EKHTKKKKQKWWQLWK"
                     /name="DUF536 domain-containing protein"
     gene            16873..17043
                     /locus_tag="PML77_RS13825"
                     /old_locus_tag="PML77_13825"
     CDS             16873..17043
                     /locus_tag="PML77_RS13825"
                     /old_locus_tag="PML77_13825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002292472.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNSP
                     NEELFVKETDK"
                     /name="hypothetical protein"
     gene            complement(17355..17816)
                     /locus_tag="PML77_RS13830"
                     /old_locus_tag="PML77_13830"
     CDS             complement(17355..17816)
                     /locus_tag="PML77_RS13830"
                     /old_locus_tag="PML77_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002305240.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFSFT
                     HGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
                     /name="helix-turn-helix domain-containing protein"
     gene            17949..18323
                     /locus_tag="PML77_RS13835"
                     /old_locus_tag="PML77_13835"
     CDS             17949..18323
                     /locus_tag="PML77_RS13835"
                     /old_locus_tag="PML77_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_002305242.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
                     /name="lactococcin 972 family bacteriocin"
     gene            18377..20503
                     /locus_tag="PML77_RS13840"
                     /old_locus_tag="PML77_13840"
     CDS             18377..20503
                     /locus_tag="PML77_RS13840"
                     /old_locus_tag="PML77_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002323538.1"
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKYG
                     TPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFDTI
                     KDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTLSIY
                     HLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYWERTT
                     NLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENNKEFFI
                     GQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYILVPKKY
                     KEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSFNTLYGKA
                     KDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQINPYIKEFNL
                     ENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVSFTINSKKIA
                     LKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIFLINLITSIII
                     YKKNSFKYFKENIL"
                     /name="hypothetical protein"
     gene            20500..20760
                     /locus_tag="PML77_RS13845"
                     /old_locus_tag="PML77_13845"
     CDS             20500..20760
                     /locus_tag="PML77_RS13845"
                     /old_locus_tag="PML77_13845"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_272019278.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTLL
                     NNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISGSVAKF"
                     /name="ATP-binding cassette domain-containing protein"
     gene            complement(20794..21474)
                     /locus_tag="PML77_RS13850"
                     /old_locus_tag="PML77_13850"
     CDS             complement(20794..21474)
                     /locus_tag="PML77_RS13850"
                     /old_locus_tag="PML77_13850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<21550..22005)
                     /locus_tag="PML77_RS13855"
                     /old_locus_tag="PML77_13855"
                     /pseudo=""
     CDS             complement(<21550..22005)
                     /locus_tag="PML77_RS13855"
                     /old_locus_tag="PML77_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /name="conjugal transfer protein"
     gene            complement(22002..>22715)
                     /locus_tag="PML77_RS13860"
                     /old_locus_tag="PML77_13860"
                     /pseudo=""
     CDS             complement(22002..>22715)
                     /locus_tag="PML77_RS13860"
                     /old_locus_tag="PML77_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /name="C40 family peptidase"
     gene            22747..23427
                     /locus_tag="PML77_RS13865"
                     /old_locus_tag="PML77_13865"
     CDS             22747..23427
                     /locus_tag="PML77_RS13865"
                     /old_locus_tag="PML77_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            23625..24230
                     /locus_tag="PML77_RS13870"
                     /old_locus_tag="PML77_13870"
     CDS             23625..24230
                     /locus_tag="PML77_RS13870"
                     /old_locus_tag="PML77_13870"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     BGC             12949..23323
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          15554..16290
                     /name="rep_cluster_1742"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12859..13769
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.342"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 acacggacgt tgttgagtgt agcagaaatg gaacgtgata tgattgtgga acgtacccaa
       61 gaaggaaaaa tgtttgcaag aaagaataat cctaatttca gagaaggacg tccgaaagca
      121 acaatcacac cgaagaagag gcacgcatat gaactgctta cttcaggtaa atcgtataag
      181 gaagttgaag ctataaccgg tttcagtcgc agtacgcttt ttagaataaa gaagaaaatt
      241 gaagaaagtt aaaaaagaag tctcagcgaa ccagacaggt aaatacttaa tgcgttctag
      301 atatgagtct attagcatgt tgtgaaatat aatatttttt tatttacttg atttctgctc
      361 aaaaaatgtg tatggtaact gtaaaaggta aagtaattaa aggtatgcta gccacgctta
      421 ctatattagg ataccatcat atatttataa tgaacgattt gttcgtctac caaacaacac
      481 atatcgttca gcgtaagtca cgtttaggaa cgtggctttt ttagtgttat tatcgataaa
      541 taatctattg actctattga ttttatctcc atatccctac ggtgttgatt gtctttagat
      601 ctttcattta agaaccaaat aactatcata aaaatcagca ctgctgctaa ggttctgttg
      661 caaagtttta aataatttga tttgtcaaat taagctagac aaaatatctt cattcatgta
      721 actcataaat acttccaggg gtgtttgata atccaaggac tttcgtggaa tattgtttct
      781 cttattcgcc actgaagaga taaaagcttg gtcgacttga ttaaaatcca tgttttttgg
      841 cagaccatct tttcgcagca agccattgga attttcattc agtgctcgtt gcgaaggagt
      901 ccctggatca gcgaaataaa tagcgatgtc atgttggtta cttaaagcct tccaattaga
      961 gaattctttc ccacaatcaa aggtaatgga tttaaataaa tgtctgggaa tcgatccaaa
     1021 ccagtggttc agagtattct caatatcgat cgccttgcgc ccctcgggct tcaaggtgat
     1081 gatgattttc gatagacgtt ctaccaaagt tatgacagca ctcttatgat gaatgcctac
     1141 aatggtatcg ccttcgatat ggccgaactc ttctttaaat gtcgggtaat cagtttctct
     1201 ttcaacgata ttccgtttaa aagcctgttt tcctcggcgt tcttgatgtc catttggttt
     1261 ccgcttaccc ttcatgggca aagtcgattc atcgaacacc ttttccttga actggcgata
     1321 aagggttctt acggaacagc tgattggttt ctctttacgc ccaatgataa cgtctggcgt
     1381 ccagccttgg gcaatttttt ctttaatgta ggactgttgt ttctttggca agacgatgtt
     1441 tcgtctgcca caccgtttct tattttcttt atactgttgg tagtattcga gggccgtatg
     1501 gccttctttc aagaaattaa tgacgttata aatcggtgtt cgagatcgtt tcaggtactc
     1561 agcaattttc acaattttga tgttttggtg gtagtaagac tctatcatca ccagttcatc
     1621 cgtggtaaga tgggtgtagg tcattcgtga tcactcctat gttttcttta gtcggaatta
     1681 cattttgagt gtagcacgaa tggcttattt atttgtctag cttaatttta caatcggcgt
     1741 aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat aataccttga
     1801 tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc ttatataatc
     1861 ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt cgatagaatt
     1921 tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg tatttaatgg
     1981 tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag gcacttgtaa
     2041 tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct
     2101 taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata tccaaggtta
     2161 aaccatctgc atcgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg
     2221 tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga
     2281 gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac
     2341 gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca
     2401 cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaatgattc atcgtcattc
     2461 ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac
     2521 agaaccgttg atttcataat aatactcaag cagctcacgg gaatagggtt caattcgacc
     2581 gctgggcaaa ataagcatac ggctaattcc gatttgttcc acaaaggatg ggttatggct
     2641 aacggcaata atggttccct caaacaaatt gaagttgccg ccaatgattt tctgcgtttc
     2701 tgggtcaagg tggttggtcg gctcgtccag tatcaaaaga ttggctttct gtaataggat
     2761 tttgcaaagg gcaacccttg ctttttctcc aggggacagc acagatactt tcttgtttac
     2821 atcgtcatca taaaacagga agttgctcag tacggctctg atttgccacg gtgtatatcc
     2881 ttcagactcc acattgtcaa tgaccgtttt gttttcatca agctgttcga gttcctgtgc
     2941 ataatatgca atatcagttt tctggttaaa gcgaatgcat ccttcatctg gactgagaat
     3001 acccatcatc aatttcaata aggtggattt accgacaccg ttttcaccca ccacaagaaa
     3061 tcgttctctt ccgttaatct gaaaggaaag gttctgataa agggtgggat accccgaata
     3121 gtggaaggtg atattttcca cctctaaggg aacttgtgcc ccttcacgct tggggcgaat
     3181 atccatcttc acacgcttgt acagtcgatt tctcttttgc agctctccac gctttttatc
     3241 aagccgcaag gctcgctctt gacccattcg tttgaggtga tgattggtct gactggcttg
     3301 ttttgctttt tgtacaaaat cggaaagctc ctttatttct ttttcctgct gtacaatcgc
     3361 catttcacga atccgctgtt cctctgcata ctttttcttg tagatgtagt agtctccatc
     3421 ataaacagat attttatggg tagctttgtt gatgtacata attttgttga taatccgatt
     3481 tagaaaatca atatcatggc tgataatcag taccgaaccc ctataattct ttaagtattt
     3541 tataacaaaa tcctttgtgc tgacatctaa atggttggta ggctcatcca acaatagaat
     3601 ttccggtttt gaatatagta gtctggcaaa tgccattttg gatttttgtc cgcctgaaag
     3661 ctctctcatc ggacgatgat ataattctgc atcaatgctc attttatctg caaactccaa
     3721 cagaattgtt tctgcctcat agaagtcgaa atactccaag cgttcttgca atgttcccat
     3781 tcgggcaagc agtgcttcct gctctgcatt gactgcggtt tcaagctttt tatagatttc
     3841 ttccaattcc tgctcatact ttttaatcgg acgtccctca aaaaggaaat cccaaacggt
     3901 aatatcctca tcttccaaga caatttcctg tgggagataa ccaatacggg catttccact
     3961 ggtcagtgaa ccattatcaa gttcaagttc tcccaacagc aggcggaaca aggtggtctt
     4021 tccggctccg ttcacgccga caataccgac cttatccaaa tctccgattt gaaactcagc
     4081 atcctcataa atttcttcca acccaaaggc taaattcata tttttacctt tcatcttgta
     4141 tcattcctcc atcgtcatac atactgcaag ccatcatttt atggcttaca gttttccttg
     4201 cttgattatc tcctgtgcgg ggatatattt tcttctctga tatcatcatt taaaaaataa
     4261 aagcagaggt agcaatacgt cccatagacg tagccctctg ctttttcaga cactatgcca
     4321 ataacataga tgaaatatag acagcaaaag gccgtagaca aaacattgtc tacggccaca
     4381 tatccaatca ttgagtttgc ttattgaaag gcaacacaaa taaggctctt aaatcacaaa
     4441 tttctgattt aaatagccct gcctctcaaa taaacatttt atctgattgg gctccacaca
     4501 atgctctgtc ttatattgtt gtgtagagcc aaaatcaatg caaaacttcc cgaataacac
     4561 tgtgctcacc ctctcttatt ttatatttta attatagaga gcttgagtgc atatgtcaat
     4621 agctcatcta agctgctcac tttacagttt gtttatagac caagtattgt acaactgtaa
     4681 actgaatatg taacgcaaaa gaggaaacag aggggtaaaa tcctctgttt ttcttttgcc
     4741 cttttttaat atgcaggcaa gccataacca tagacaacgc tactgccgat aggatagcta
     4801 tactcgttta ataggatagt aagaaatgct cattttggtt ctgttgcaaa gttttaaata
     4861 aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat
     4921 ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc
     4981 tcggatggct tccatgcctt taatcgtggg tgaggcagtg cgtaaacttc gatagaattt
     5041 attgcgtctc tttactggac gatggtcttg ttcaatcaaa ttattcaggt atttaatggt
     5101 acgatgttct gtcccttgat aaaagccgta ttcttttagt ttcttaaagg cacttgtaat
     5161 agagggggct ttatctgtga ctacaacctt cggttcatca aactgcttca ctaaccgctt
     5221 aagaaaagca taggctgctt gtgtgtcccg ttttttacgt aaccaaatat ccaaggttaa
     5281 accatctgca tcgatggctc gatacaaata atgccatttt cctttaattt tgatgtacgt
     5341 ttcatccatt ttccatgaat aaaaggattt tttatttttc tttttccaaa tttgatagag
     5401 tagtttgcca tattcttgca cccaacgata aatcgtcgta tgagaaacgt taatgccacg
     5461 atcatataag atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac
     5521 ggctacaata atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc
     5581 tcctgctatc tttttctatt attctacctt atttgatagt agatttaaaa ctttgcaaca
     5641 gaacctgata tgggattcaa tagcttacct ttaaatgata atcacatcat taaagaaaat
     5701 actacaactg aaaagcgaag taaaatagac aatttatatc atgggtcaaa agaggatttt
     5761 actgaattta aaataccaag atttcataaa aatggtggaa cattaggctt tggaacttat
     5821 ctaactgata gcttgcaaag agctaaatct tatgcagata atgacggcta tttgtatact
     5881 attgaattga atgatgaact acaaaatagt acacctttga acgccagcaa agttacatta
     5941 acaactaatc aagtcgctaa aataattgaa aagatagcac agaaacagat tgatgaagaa
     6001 gaatacccct acatcttgtc cgattgggaa gaaccaacta gtgaaacagc aatggacgca
     6061 ggcaacaaaa aaattgctta taatatagct gaaaagatta ttgatgatac tgatgattta
     6121 agcattatca atggcataaa caatcaatta ggcggtaacg atagtggagc agaaacacta
     6181 attcctgttt taaatgaaat gggtattcac tatgcagaat tagatgttga atactatgat
     6241 aattccaaag aatacgttgt atttaatcca aaggatatta aaatcgttaa tcagaaacta
     6301 acaaaaccag aacaaagtaa aaagtttgtt agtgatgttg atataaaatc cttggaagaa
     6361 aaagctataa aaacaatcgc aaaatctgaa ctaattgtta aagcaaacaa cccagttgaa
     6421 gctatgcaaa agctttataa caatgattta aaaagcgcta taaaagccag ctttatatta
     6481 tatgatttac cagaagataa aatcgacagc agtaaaaaga atgttacatg ggaagattta
     6541 gtcaacatag aaaaatcata taatgtgttt agttattatc aaaacaactt atacggtagt
     6601 gaacttgtag aacctgattt gaacaatcca tatcaggaaa acactaagat tcttgataat
     6661 aaagccacac aaaaacaacc agccttatca gatcaataca aagcattgca tgataagtta
     6721 aaagagccag gtgcaaataa acaacaaata caggaacaac taaacaaagt taaaatcgaa
     6781 attagtcaaa agacccagca acaattaaaa gactttgcaa aagctaaccc agatttgaag
     6841 caaccaagag taaaaaaaga acagcaagct ttgcaacgat aatcataaaa agcgcctatt
     6901 tataggcgct tttttgtatt ttgacgtttg agaggcgcat tctaagaccg ttgtgacttt
     6961 acttgctaaa ttagaatgat tttacttaat aaatgagaaa atgaaacgta tggaatgcta
     7021 tacaatatta tgaattgaaa aaagtgatag ttagatagtg tacagaaact ggttattttc
     7081 ttggctaaaa tgcaaaacag ggcttgttaa taagccctgt tttttaaaat tatttagttg
     7141 ttcttgctat taacaattta gtttctgaat aatatttaaa aacagatgta tatctgtgta
     7201 ataaaaaggt tttattgctt taaatcccta ctacttatat ttaaagtaac aattaaagca
     7261 actaacacga tgcacgtaat ggttaaaaat atatcagaat agtgcggggc agttaaagta
     7321 taaaaaggat taaaagatgc tttaacccca tgtctcattg acaataaagc ccctattagt
     7381 gaggcacctg ttcctgcccc aagatacatt gcaccttgaa acaaccccgt acctacacca
     7441 acttgttctt taggtaaagc aagtactgca acattattca ctggagagtt aataaatgca
     7501 aaagcgatac ctatccctaa actcccgata gataataata caggtgatgc gcctgctacg
     7561 aagctcatat ataaagaaga taagcccata ataattagtc caactaataa tagtatttta
     7621 ggatgcactt tgtcagataa tcttcccact attggtgaaa ggattgcaac agcgacacca
     7681 ccagaaagta atattaagcc tgcctgtcca gtacttaacc cattaacctc aacaactaat
     7741 aatggaataa aaacaagcat agagacataa gcaaacattg aaagaaatac aatgaaaatt
     7801 gagcttacat ataaacggtt cttcaatata actggaggga taaaaggatt tttaacatta
     7861 atcacgcgat atattaacac tattaaagct atcatagata tagaaaaact tgtggttgtt
     7921 tgtatagaaa tcaaaccata catttctgaa agcgtaatac caagtaaaaa accacctacg
     7981 gttaatccta ataatagtcc acctaaaaca tcaaaatttt gatgactgtt attatctggt
     8041 gattctattt taggcattga tatttgaaca cctagaacta taattaaacc cagaacaaaa
     8101 gtgacccaaa ataatgattg ccaacctaat aattgtccta caacgccgcc aaatattggg
     8161 cctcctgcag tgccaacgcc aatacaacca gcaataatac ctaaaattct tcctctctgt
     8221 ccaggcggat aaattttaga tattataaca atagatagca caggtatggc tgccatgcca
     8281 gctccttgaa acattctacc caatactaaa ataattaaat tgggcgcgaa tatacatatt
     8341 aaacttccta tagttaatat tagaaatccg ttagtaaaga gttttttaat atttaaaaaa
     8401 tcagataaac gtccataaaa gggaattgct atagatagaa ctaaggcaac accacttacg
     8461 acccaactaa cttgcgcctc agacccacct aattcttttc caatcacacc gagaacagga
     8521 ttaaccatat ctgcagtaac tgaacccact aaaacagaca agcctaagat actaattaac
     8581 aacacatttg atgctatatt tttttcattt tgatgattca ttttacagcc tcctaaaatt
     8641 taaatgctca ttttagaagg ctaaatcgac tgctttaacc atcaatttca cctctcaatt
     8701 atccaaataa aaaacctaat cttaagatca gacttttgtt acataaatca atattttact
     8761 tttttacgta aggattatag taaaaagtct ggattttggt attctgttta aaaaagtaca
     8821 tacttgtccc tcaactttga gatagtctga aactttaatt gttttataaa gggtaaacac
     8881 catttccatc atttttatcc tcctcttata ttaatctata ccaaaataac acaaaagagt
     8941 aaatttgtca gttttatctc tattttgagc aaaatagagt agtaaatttt aaaattatga
     9001 gtttatttga ttatttttaa tactctatat agtttgtcta gtaacatcta cttccgtaac
     9061 tatattgcta attgaaaaac atttgtctaa catttctata actcagtaat aaactaaacg
     9121 tttttgagaa tcttttgcat ttggtgaata aagtacaggt cgtcctttgt atactccttt
     9181 ttctttcgct actttaatcc cttgcgtttg ccgacgttta ctctcatttc tttcttgttc
     9241 tgaaatcatc taagacaaca gttagccaag gtctttcaag tttgtttttt tcgtttaaaa
     9301 cctctatatc taacatagta tgatctgctt gccaaatttc attaggatgg ttgcattctt
     9361 taagatagat agcatcatac ttttcagcat atttttaaag acacctttaa ctttggaatt
     9421 agtatagtgt ttgaattttt taatggtaac agaagtaatg ccaagtaacc gcatgatttt
     9481 ttgaacatac ttaacagaaa cattatagcc tttttgtgtc aaaaaagcgt ggattttagg
     9541 cgcaccatag atgccattat attgatggta taaggctttg attaaaactt taaaacgaag
     9601 gagtctctca tttctaacag aatatttctc tttaatacag taataatata agcttcttgg
     9661 aacatttaat atgcggcata gatggctggc attaaagatt tttgaatagc gtttaatcca
     9721 acggacttta gttaaagtgg atcttgagcg aatatggcgg ctgcctttct tagtatttca
     9781 ttttcgagtt taagttgttt tatttctttt ctaagggttt gcatttgttt ttcattaaca
     9841 ccggttttag agtctttcgt gtataatttt ttccatttat aaatggctgc ttctgaaatg
     9901 ccatactcgc tacttaaatc cttcgctttt gtcccattat tagctaaatc aacaatcatt
     9961 tctttaaaag attcactgta ctttgtcatt ttagacacct tccttagtct cattatattt
    10021 gattcaagac tctacgaaaa ggcgtcctaa ttttcatact agcaccaact cccactaatt
    10081 gaggtcagtt caaaacgtca gtattttctt tttttaaaat tgtaatcata atttactttc
    10141 cgtatttttt ggtggccaca caaaatatga aatacaaatg attaagtcaa taataatgac
    10201 aattgtccaa acatgaataa cattatccat agcttctgta cgacttttat cattaattaa
    10261 aaaaataatc aaatgcaaaa tacctgttcc tataatgtaa gaaagtaaat gtttcaacca
    10321 acttttagca tagtttttag agtaagctaa tcctacaggt ttgtaaggtt tgggtccttg
    10381 tttcatcaca taatatccaa atctatcatc tgcccaattt atcatgcttt tcccaaagac
    10441 aagagatact gaaatataga ccgcagctat agcatgaggg gttgcagctg ttgctccatt
    10501 catgaggtct atacctgttg ttataagtaa tattaaatct ataactggtg taagtgctag
    10561 gaaaaataga cctagtgttt tttgttttaa gatatatctt gttacggttc tgttgcaaag
    10621 ttttaaataa agaataaaat cccttacggt atctataatt taagctggga ttcccaataa
    10681 taccttgatt tcagtacaga ccgaaaaccc gaagagagtg ccttcttttc gggttttctt
    10741 atataatcct cggatggctt ccatgccttt aatcgtgggt gaggcagtgc gtaaacttcg
    10801 atagaattta ttgcgtctct ttactggacg atggtcttgt tcaatcaaat tattcaggta
    10861 tttaatggta cgatgttctg tcccttgata aaagccgtat tcttttagtt tcttaaaggc
    10921 acttgtaata gagggggctt tatctgtgac tacaaccttc ggttcatcaa actgcttcac
    10981 taaccgctta agaaaagcat aggctgcttg tgtgtcccgt tttttacgta accaaatatc
    11041 caaggttaaa ccatctgcat cgatggctcg atacaaataa tgccattttc ctttaatttt
    11101 gatgtacgtt tcatccattt tccatgaata aaaggatttt ttatttttct ttttccaaat
    11161 ttgatagagt agtttgccat attcttgcac ccaacgataa atcgtcgtat gagaaacgtt
    11221 aatgccacga tcatataaga tttcttgaac ttcacgatag ctaaggttat aacgaagata
    11281 gtagcccacg gctacaataa tcacatcctg ctgaaattgc tttcctttaa aatgattcat
    11341 cgtcattcct cctgctatct ttttctatta ttctacctta tttgatagta gatttaaaac
    11401 tttgcaacag aaccatatta gctatttatt tcaaaactat gctcttcttg aaaatcaaac
    11461 agtacaatac aatttcgaat tagcaaaaaa gtttaacagt aatatttcca atgatcatat
    11521 ttataattta ttaacagatt tttctttgcc aaaagatatc ttaaaagaaa aaatctttct
    11581 cttaagcggt ggagaacaac aaagaatagc attaattaga aatatgttaa aaccatttga
    11641 tatattattt gcagatgaac ctacaggaaa tttagataaa gaaaactcaa cttttataat
    11701 gaactttctg aaaaatttaa cagaaaaaga aaaaaaagcc gttgtactag taacacatga
    11761 cttaaatgtt ctaaactatg gaactaatat tatagaatta taatttttac ccgtgatgct
    11821 agctgattta aaactagcac cacgggtatt tattttatat tccatctctc ctatcccaaa
    11881 atttaaataa tcacttaata aaaaggaggc acccaagtga ttttattgaa aaaagagtat
    11941 gaaaaatttt atgatagact tatttattct ttgcaattgc caaaaaaatt aaaccgtcaa
    12001 ttacaaaaga cttatgaaac taaatcaact gaagaatggg agagttattg ctagattttt
    12061 ggtagaagta acaaaaagtg gacatattat cataatgact cgccgaaagt ctgataaaaa
    12121 attggctaaa aatattgctg aatgtttaat aaaactatca gttttagcta aatagttagt
    12181 agtttacaca aaaaagcatt tatgtttttt gttgcaaagt aacaatttca tcttcggtga
    12241 aataagcgaa actttacaaa aagtggctag catttgctag ctttttttgt attgtggagc
    12301 gtggcttttg agggggattc aagggggagc ttgcgcccct ttgacaagcg gttatttgca
    12361 ctaaatacgt aggtatttgg ctagcaaata tagagcttgc caaacccttt tagtgagctt
    12421 tactcattgt acctttttag gtacaatggt attgcgaacg atacgtccgt aggacgtact
    12481 gaaagggtgg gacttatgag cgaacaaaat caaaatttgg ctagcaattc ttctaaaaaa
    12541 tatacctatc gatccgagcc aaaacaaatc agttttcgag tgagcgaatc cgaatttgca
    12601 aagctgaagc aatcggctga agctttgcaa atgagtgtgc cggctttcgt gaaagccaag
    12661 gcacaaaacg cgcgtctggt gacaccgaaa gtggcgccag acattgccca ggcaatcgcg
    12721 cgcgatttag ccaaagctgg agggaatatc aatcaaattg ctaagtggtg caatacacac
    12781 caacatgacg ttgcttctgg tgacgctcaa cgtttatccg aaaacctaaa aatcatgcaa
    12841 aaggagctac aaaagatatg gcaacaatta aggtaagccg aaccacttct tgtagtcgtg
    12901 caattaatta cgcagaacca cgagcaacca ttaaaacagg aataaactgt gacgtcgatt
    12961 atgccaaaag tgaaatgaaa caaattcgca tgctgtatgg aaaagacgac cgtgtacagg
    13021 cacacttatt gattcaatct tttcgaccag gagaaattac cgctgaaaaa gctaatcaac
    13081 taggggcaga gtatgcaaaa aaaatagccc ccgatcacca aacagctatt tacacacata
    13141 cagacaaaga ccatattcat aatcacattg tcattaactc cgttaatctg gagactggaa
    13201 aaaaatttca agctcatggt caagcatttc taaacaaatg ttatgaccta aatgacgaga
    13261 tttgtcttgc acataactta ccaatcactg agcgaggaaa gaaaccagaa aaacgaacca
    13321 tgtctgaaat aaaattaaaa gaaaaaaatg aacctgtttg gaaagacgaa attcggattg
    13381 cgatcgatca aacaatgaaa aacaaaaaaa ccagaaccta tgaccaattt tgtaattccc
    13441 tcaaaacatt ggggattcat tgcttcaatc gcgggaaaaa tttcacttac gaattgatcc
    13501 acaaaaagaa aaaagtacga tccaacagac taggaaagga ctacgaaaag gagacgattt
    13561 tacatgagct ggacagacga gaacgaacct ataaccaaca gcgaaccaac gagctacgaa
    13621 gagctcgagc tagcattcgc gaaactgcag aagaagtacg aagagaacaa cgaactctta
    13681 cgcctgaaca accggaaatt agaccggctc gaagaaacca tgaacaacac gttgaaagag
    13741 gaacagacca ccaacaagaa ttatcgctct aaaacgttaa aagacataga aaacgaaata
    13801 aagaaacaac gtgcttttct cgttccttat acgcaagaaa ggatacaaac tacgattgat
    13861 ttacaagtta aaaaactcca tcaagagcta ttagaccagc gaaataagga acagaaaaag
    13921 gtgcttattc aacgatcatt ggattttctt gcccccttat gttgcttagt cctgacactg
    13981 ttcgcatttt ggttagtatg gggaggctaa aatggcattt tatttaccct atctactcat
    14041 ttttgttagt atttcaggaa gtatttggct catctataaa atttttcaaa caagatattc
    14101 attaaaaggc tctaaaattc gatttaagcg atttttcttt cttggctgta tattttcctt
    14161 gataatcgtt tcaagcggct tattcggcgt tttagaggga aataagcgcg tttctagaag
    14221 tattttatta ggaaatgtca ctcaaaagta tgaatcagcg cgtgataaaa agaaaaaaga
    14281 gcaagcatta gcacaaaaaa tggaagagtt taccacttgt tatgaggaaa tgaacgatat
    14341 ttttgtgaat caagaaaaac gtttgacgga taaaaacatg gaaaaactca ctcgtcttta
    14401 tcaaaacttg ccagaaaaac agcaaaaaga ggttcaagac aactatgagc gaaccaaaaa
    14461 agacgtgcaa tatgtaaaag atacaaagat agaagaagcc tgtagtgatc tatttggaga
    14521 cacaaaccct tggtttgcca gtgaagaaga aaaaaaagaa aaacaacaat ctgtcacata
    14581 tgaacgctat gaaatcttac ttcaacaagc aactaacatg caaaatccga caaaaaaaga
    14641 aaccgcctta aactatctaa aaagtgtcaa ggaatggtta gatcagcaac aacaaaattg
    14701 aatttgattt aaaatcatgt taaactgaat gtgcaaatga tcaaacatta gatacacgaa
    14761 agccccagag aggtcggatt ctctggggct ttttttcagg ttgatgtcgc ctttattgat
    14821 tttacttctt gtttcggtta ttcaaccaat aactgaataa agagacacaa actcctacaa
    14881 gaagggggca aatgaacagt tcaaacatta gatacacctc cttccagtcg caagactgtc
    14941 ggataggcga caagttatta tatcttaaaa aattaaattt gtgtggtgtt tttaagtatc
    15001 acttgtttta gggttgttag ggcttgccct gaccgcctgt aaggcgcttc tcgactagat
    15061 taagggaaat taatcaagaa ttgtcttaga acggcttaga caagctttca gagtctcaca
    15121 cctcctcttt gaacaacggt tttagcaaag gagccggagg cgactgcgca gtataatatg
    15181 agagcatagc gatcacacct ttttagcgac cgtagggagc aagttttcca gtttagaaaa
    15241 attcgcgaac ctttttggag gaaaaagtag gagtttttta ggcgggaaat tcaatgtgct
    15301 cttaagatat actgttagat atactgttag atatactgtt aataataact gttagggatt
    15361 agcaacctta tgggagagta agtattgaca taggtagtgg gggataaatt gtcacactat
    15421 gggggataaa ttgtcacact atgggggata aattgtcaca ctatggggga taaattgtca
    15481 cactatgggg gataaattgt gttttacatc ctcttatgtc tatgataaca taatttattg
    15541 aggtgatttt tattgagtaa cgatatagtt cgatataata atggattaaa ttctgtccct
    15601 ttaagaaaat ttacccctat agatatggat ttattttggg gaatatgttc taaaatgaaa
    15661 agaaaaggta caaaagaaga aatttttaca tttaaacaaa taaaagaatt aattgattac
    15721 aatataaatg cacgtggcga ccgttttgct aatgatttaa taaaaatgtc aaaaaaaatc
    15781 attactttgt cttttattta tgaagacgaa aaaacatatg aacaattaaa tctgtttcaa
    15841 aaatttaaaa tcgataaagt gaatgaaaca ttattaataa aggtttctga agaatttgaa
    15901 tatatactta attcaatcgg aactaatttt actcgtttcg aattagaaaa tatgacaaac
    15961 ttaaagagta gctacgttaa agagttatat cgccaactta tggctcataa agacagaaga
    16021 tctaaaaaag gtcactggtt tgtaaaaata gaagatttta gagctctatt agcaatacca
    16081 gaaagttatc gcatgagaga tattgataaa caaatttttg cccaagcgaa aaaagaattt
    16141 ttaaacgtta attcaactca ccctgctatt tttaaaactt ttgaaatcaa aaaaattaaa
    16201 gcctacaaag gaaataagat aggatctctg caaatttatt ttgaagaaaa tataccttca
    16261 attaccttag ataattggtt agagaaataa tacctaacaa tttaggaggc aattatcatg
    16321 caacccaaag aaacctttac aataaaggaa ttatctgaat tatttgaaat aagtaggcaa
    16381 gcaatctcta aacatgttga taaattagac ccgtccttat tagctaaaaa tgagcgtggt
    16441 tataaggttg tattacgttc tggagtattg caacttgcta gcaacttagg taaccaaagg
    16501 ttactatata ggttgcatga gtatgaacaa gaaaacgata aaaacgttta tatatcaagc
    16561 aaaaacgtga ttgtaaacga gttgctagat aagttgcgtg aagaaaatga atttttacga
    16621 gaacaacttt ccctcaaaga gcaaaataat tctaatatgc aaaaattact cgaccagcaa
    16681 caacagctca ccctacaggc aaatcaacag atcgaaaaac tgcaagaaca gttacaatta
    16741 gcttatacgg aagaaactcc agaagatgaa tcaactacta ttctttctga agaaacagaa
    16801 tcgatagaaa aacacacaaa aaagaagaag caaaaatggt ggcaactttg gaaataactg
    16861 gagggaacat tcatgacaag aaaaaatctt ctattcggtt ctattttact aggaattcta
    16921 ggcttcagtc cgatgttatt gtcagtaatc aataaaggga ataaacatgg tgaattgaaa
    16981 ttgaatccaa attattacaa cagtcctaac gaagaattgt ttgtaaaaga gacggataaa
    17041 taataaaaaa gactgctctt ccgagcagcc agttaaaaaa taatgagtgt ttattcttga
    17101 aaaagcacgc gcttatgaag cgctaccaaa aatttaccat attttacaaa aaataacaag
    17161 tcttaaaaaa atgacagata aaaatgcaca aagaattaga tatagataac cgcgaaaaat
    17221 caagctttag aaagttgctt ttagctagac caattaaaaa tcacaaagtg agcgtctcta
    17281 tccattggta gaggggctac ttggcatagt cgacattatg tcaactatgc aattaaataa
    17341 ctaactactt catattagct taataaaata atcaaaataa ctagggggaa aaacattgta
    17401 taaaaaaatt tttcattttt taaataagaa tagtaaatat aaaaataatt taagatatct
    17461 attactatta atccagatag agcaaaccaa gtaaatattc catgtgtaaa gctaaaaaaa
    17521 ttcatttgaa tcaattcaaa taaacctaat atagtaacaa atatattaaa aataatagct
    17581 gtcaatacca gtaaattatt ttttttattt tttgaattat cttcatttaa aatagaattt
    17641 atgttagtac tataaaattc acaaattttt tttagtgtct ctatatctgg tgttgttttg
    17701 ttattttccc actttgaaat agtttgacgt gtaacgttaa attttcttgc cacatattct
    17761 tgagtatacc cttttttcac tcttaattct cttagcttag atcctaaatc ctccattttt
    17821 tctcctatgt aaacgattat ttacataaaa ttttatcata aaaatactaa cgcgccaaaa
    17881 aagttcttta ttttataaaa cacactaaaa taaaataatt ctagtaaaaa agataggaga
    17941 aataagttat gaaaaaattt ttatgtcttt ctgctttaat gggtgtctta ttaactagtg
    18001 gaggaatagc tagtgccaca gaagctttaa atctagatgt acccgaagac cataccgcca
    18061 tttacggagg aggaatggaa gctacagaag aaggattttc ttctagtaaa ttgagatatg
    18121 ctgctggcgg cggggatttc aactgtgggg ttaatggatt taaagtttat gcaaattact
    18181 accatgctag agctaaacat agtgcaacag ctaaaaatgg acgaggcggt caagtacgat
    18241 cagttcagaa agctggagta agagcttatg caacatgcaa tgccacactt actggaaata
    18301 ctggttggtg gaatgtttat taaaaaagag agtttaaact ctctttttta tttacatttg
    18361 aaaggaaatt caaaatatgt taaaaaaaat aaacgctgtt ttatcacttt ttgtctgcat
    18421 tacaatacta tttttttcta ctaatgttat aaatggtata aagacttctg aagcgctata
    18481 taaaaatacc gctgaaattc atatgcaata taaagatgat atggacttta acagttatat
    18541 aaacgctttg tatgaaatat ctacacaaga aaatattaat atttctcaat atagttttac
    18601 tgctgttaac caactaacta ttcttgctac aaaccctaac gctaacaaac actggaaatt
    18661 ttctaaaaaa aatatattag caagaaacga ttctaaagtc cattatacta ataacaaaaa
    18721 ttctaagtac caattaaaac ttccaaataa ttttttaaat ataaatattt atcctttttc
    18781 tcatgtggaa aatattggat taagtgaaat attatatgta caaggaaact caaacaaatt
    18841 aattcctgta ctgaaaaaat atggaacacc tactatttcc aatatcaatc aatcagatac
    18901 ttttcaaatt aatactaata ttgttcttgt tatctgctat cttagtatat ttattgtaat
    18961 tactacaatt atatttgctt tttcaaaaat gaaagaaatc actctaaaaa aaatgttagg
    19021 ctataactct tttgatacta taaaagattc tattaaagag ttaaacctct tattttgttc
    19081 tttgattata actttcattt tatctatttt tttgagcata tattacagta acgaaaattt
    19141 tttcctatca tttcttctat gtagtatttt tcattttata attagttttt tatttatcat
    19201 agttactcta agtatctatc atttatctag tataaaaaat tatctaaaaa attcacgacc
    19261 acttaagtta aatctttgta tattaaatat ctgtctattc ttaagcatga tccttctgtt
    19321 aatagcttct acaaaagtaa taaataccca taatgaagcc gaaaataatt ctcttaaata
    19381 ttgggaaaga actactaatt tatacaaaac aaatattact aatcaattaa atagaaacaa
    19441 caccgtagaa gaaaataact acttgaaaaa agctagtaaa tttgtttata aaatacagaa
    19501 gaattataaa acttttatta tcgcgccata caattacgca actatccaag agaataataa
    19561 agaatttttt attggacaaa aagtttatcc aaattttgaa gactacgtta gtcaacctgc
    19621 tggtgcagga atatgtgttg atttaaacta tctaaaatat tacaatccta tttcttttga
    19681 agaatctact gacttaaatt taataaactc tgatccacta actacttaca ttctagtacc
    19741 taaaaaatat aaagaatatg caaaaatgat tgaaaaaaat tatttagaag acatacagtt
    19801 tagacttgag gactctcctc ctcaagctcc ttataaaaat cctaatttga aaaatttaaa
    19861 aataaaacta atatttgtta ataataacca aaagtatttt agttttaata ccttatatgg
    19921 aaaggcaaaa gataactata caataactga tcccatagtt agagttatta atccagaaat
    19981 aacagaatca ttattttggg gaaatatatt gactagtgat ggtggattat tttttgatca
    20041 gaaacatact tcaaaccaaa acttttttaa tcaaattaat ccgtatataa aagaatttaa
    20101 cctagaaaat atcataaatt tttcttattc tgtttttcaa gaaactggtg aattattatc
    20161 tcaaaaaaaa gtaaataaat taaatgcata tctacaatat cttttaatat taggattatt
    20221 tataataatt aattttcaaa tgatttttgt tagttttact ataaattcaa aaaaaatagc
    20281 tttaaaaaaa atatttggat attcaccaat aagtcaagtt ttagatttat gtttactccc
    20341 ttttacaata gagttatttg ctactatgtg ttttcaattg atattttcaa aaaacactta
    20401 cttgtatttt ataattttta tgatcttttt aataaatcta attacttcta ttattattta
    20461 taaaaaaaat agttttaaat attttaagga gaatatttta tgatattatc agttgagaat
    20521 ttcaccctgt caattaataa aaaaaagatc aaacaaaatt ggaacttttc aatatcagaa
    20581 aaagatttta ttatagtaac aggaaaaagt ggtagtggaa aaactactct gttaaataat
    20641 ttaagcctaa tagataaaca atataccggt aacttattct attttgaaaa gaaagtttct
    20701 aaacatgata tacaacgtct acgaagaaat catattagcg gttctgttgc aaagttttaa
    20761 ataaagaata aaatccctta cggtatctat aatttaagct gggattccca ataatacctt
    20821 gatttcagta cagaccgaaa acccgaagag agtgccttct tttcgggttt tcttatataa
    20881 tcctcggatg gcttccatgc ctttaatcgt gggtgaggca gtgcgtaaac ttcgatagaa
    20941 tttattgcgt ctctttactg gacgatggtc ttgttcaatc aaattattca ggtatttaat
    21001 ggtacgatgt tctgtccctt gataaaagcc gtattctttt agtttcttaa aggcacttgt
    21061 aatagagggg gctttatctg tgactacaac cttcggttca tcaaactgct tcactaaccg
    21121 cttaagaaaa gcataggctg cttgtgtgtc ccgtttttta cgtaaccaaa tatccaaggt
    21181 taaaccatct gcatcgatgg ctcgatacaa ataatgccat tttcctttaa ttttgatgta
    21241 cgtttcatcc attttccatg aataaaagga ttttttattt ttctttttcc aaatttgata
    21301 gagtagtttg ccatattctt gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc
    21361 acgatcatat aagatttctt gaacttcacg atagctaagg ttataacgaa gatagtagcc
    21421 cacggctaca ataatcacat cctgctgaaa ttgctttcct ttaaaatgat tcatcgtcat
    21481 tcctcctgct atctttttct attattctac cttatttgat agtagattta aaactttgca
    21541 acagaaccca ttaaactcat tgtcgccagt tggctctacc gtccatatct gaaatcctct
    21601 tacagaagac gatacaggaa tatctttgcg tactgtatca acattgagag cttgaagttc
    21661 atctgtcaga tagcctttta gactttccat tcgattatca atggacttat cggattgctc
    21721 ccatgaatag tagactttcg caaagttctc tacaaaattt tctacatgat gagtatcaac
    21781 gtattccttt tctatgatag ttgtttcgtg aatagtatga gtatctatag ctgtaaagtg
    21841 cttgaatatc gcaaagctga aactaagccc taaaagtacc cacaaggcaa tcacaacctt
    21901 tttatgagga ttgaccttat agacacgagg tttcttttcc tttggtatct gtttttcttt
    21961 attctgattt tttctaaatt tcatcattaa atcttccttt ctcattgttt gattcgtcct
    22021 gctcccacta aatgctgttg ccagtagggg cttgttaagt cggcataacc gattgggtcg
    22081 cctgcatgaa acatacggtt attgccaagg tatatcccaa catgagtaat ataagagcca
    22141 gcgttatagg tagaatgaaa gaaaaccaaa tcgccagctt gtgcttccga tagtgggata
    22201 tgctgggtca catcatattg ctgttgtgcg gttcgtggta agttaattcc agcttttcca
    22261 tacgtccatt gtgtcagtcc gctacaatca aaagaagtag tcggggaagc tccaccgtaa
    22321 acgtatcgcc agccctcata tttcagtgct tcgtccatga tggcttgtac cgtatcatca
    22381 tcaaactctg ttgtgacaag atactgcgtt accagttgca cataaaacat attgccatag
    22441 ttgtatcgcc agcccccatt gataggtatg gctatgggat tggggtaaga cactttttcg
    22501 ccacctgaat actcttttga gaaactttga gccagttcaa aggtatattt atttccacga
    22561 ttagccacat accctaagaa accaccacca taattgtagg actggataac cgattctaaa
    22621 tctacactga gcctttcgct actggctaat aattcactga aatacttcac acggttctgt
    22681 tgcaaagttt taaatctact atcaaataag gtagaataat agaaaaagat agcaggagga
    22741 atgacgatga atcattttaa aggaaagcaa tttcagcagg atgtgattat tgtagccgtg
    22801 ggctactatc ttcgttataa ccttagctat cgtgaagttc aagaaatctt atatgatcgt
    22861 ggcattaacg tttctcatac gacgatttat cgttgggtgc aagaatatgg caaactactc
    22921 tatcaaattt ggaaaaagaa aaataaaaaa tccttttatt catggaaaat ggatgaaacg
    22981 tacatcaaaa ttaaaggaaa atggcattat ttgtatcgag ccatcgatgc agatggttta
    23041 accttggata tttggttacg taaaaaacgg gacacacaag cagcctatgc ttttcttaag
    23101 cggttagtga agcagtttga tgaaccgaag gttgtagtca cagataaagc cccctctatt
    23161 acaagtgcct ttaagaaact aaaagaatac ggcttttatc aagggacaga acatcgtacc
    23221 attaaatacc tgaataattt gattgaacaa gaccatcgtc cagtaaagag acgcaataaa
    23281 ttctatcgaa gtttacgcac tgcctctacc acgattaaag gcatggaagc cattcgagga
    23341 ttatataaga aaacccgaaa agaaggcact ctcttcgggt tttcggtctg tactgaaatc
    23401 aaggtattat tgggaatccc agcttaaatc atagataccg taagggattt tattctttat
    23461 ttaaaacttt gcaacagaac caactagact gtgcaaaata gagacacttg aaaaatctat
    23521 cgggggtcag aaacttaata gtttttgaca cataaacaaa atcgcgatat aatggggttg
    23581 agagtgtttc ataaacttat gtcataaagt taaggagatt tcgcatgatt ttagagaata
    23641 aattgggatt aaccaatcaa gttgagttgg ctaaggttga agaaaaactc agtaaacaaa
    23701 aagcgaaaga attgtacgat tgtggaaaaa taaatgaaat cgaagttggt acatttaaag
    23761 gtttatctga aattcatgaa tttctatttt cggatattta cgattttgcc ggaaaaatcc
    23821 gatcggtcaa tattgcaaaa ggaaattttc gatttgcacc agttatgtat ttagaacatt
    23881 cgttacagca tattgatcag atgccacaaa cttcttttga agagattatc aagaaatatg
    23941 tggagatgaa tatcgctcac ccatttcgag aaggaaatgg ccgaagtact agaatttggc
    24001 tggatctcat tttaaaggaa gaattgcaaa aagttgtaga ttggaactta atcgataaag
    24061 cagactatct ttctgcaatg gagcgaagtc ccataaacga tttggaaata cgctatctaa
    24121 tttccaatgc tctgactgat aaaattgacg atcgcgagtt atatatgaaa ggaatcgatg
    24181 tcagctattt ctatgaaggg tattctgagt atacgataga tgatttgtaa aagtaggtgg
    24241 accaaatgac gaaatatgga tatgcacgtg tctcaaccgc ttctcaaagt acaaaagaac
    24301 aaattcaaca gttgcttgag aacggcgtag agaagaagaa tattttttca gaaaaattta
    24361 cgggtacaaa acgggatcgg ccaaaattca atcagctgtt ggctggtctg aagcctggag
    24421 atgaaatagt tgttacgaag cttgatcgat ttgctcgtaa cacgagagaa gcattagaga
    24481 tcattgaacc tttactcgat gataacgtaa cgatcaaggt tttgaatcta ggaacgattg
    24541 aaaatacgtc catggggcga atggtg
//
